LOCUS       NZ_FWXV01000003        20459 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000003
VERSION     NZ_FWXV01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 438550
            Orig. end                         :: 459009
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20459
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phenazine"
                     /region_number="6"
                     /rules="phzB"
                     /tool="antismash"
     cand_cluster    1..20459
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="phzB"
                     /kind="single"
                     /product="phenazine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20459
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10459](-)"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10459)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
     misc_feature    433..447
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            complement(542..3916)
                     /locus_tag="B9C43_RS21030"
                     /old_locus_tag="SAMN05661093_04287"
     CDS             complement(542..3916)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.5"
                     /locus_tag="B9C43_RS21030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04287"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_143446486.1"
                     /transl_table=11
                     /translation="MPLGIEASALGEQGRRTAPRVELLGPVRVVNADVEIGLGPARQRA
                     VFVVLAMRSGQTVSRAELVEAVWGRSAPASADGSVYTYMSGLRRTLGDLGRELIVSSGN
                     GYSLRVDSQQVDVTLFDELCEQANALAARGDHRGVTEKLGEALVLWRGEAFAGVPGPFA
                     EQERTRLEQARLRAVETFARARLELGDHVEVAADLEVLVRDHPLRESLRELLMIALARS
                     GRHAEALDVFADARATLLRELGAHPGPALCQVHADVLAGNEMFQAEPDTPRLDVRPCSA
                     ARDKDRPFVGRRAELEQVRERLAGVSQGAGGAIWIEGEPGIGKSALLGAALADVDINAV
                     QVGWAVADELAGRFPLQIMLECLGMGRKLPQGESVGSMIERICATGPLVLVLDDIQWAD
                     EDTVQTWRRLCEATNRLPLLLICAANTGHGRAELTELRRYIESGAERGTAIAMRPLSFV
                     ESEALLTELVGARPGRVLRRITSRADGNPLYMREVVNALLLDGAVEMIDGVAYIDESKA
                     EDAPRSLVAAVERSSKSLSDSTKEMLVWVAVLGPEATIGNIAAVSERPVWYLVRAVTDA
                     VNANVLVEEGPKLTFRHQLMRDTVYGGIAGPTRGVLHRQAAKVLAEAGAPPHRVSEQLV
                     AAGGYVEPWVAGWLAEHVAELAGRAPQVAAELLAQVIDTLDIGDPNREVLQAIEVRVLF
                     QLSRDPEAKARHALAICTDPVLAAEVRQLLAAIVYRQGRRVEAISILTEVPVDPALPEQ
                     WRLRHRALLAYLRRDMSNIDTAEIAAKDAYEEAITAGDSFYAAHALQTRWLVDSMRRDH
                     LAALRHVDEAIDLVRERKEYVGMQYDLLDNKIYTLQNLDRLDEADATLGVAADICPVNG
                     LPIGLHVTAAVHHYWRGRWDEALQALTTITGDGPTITYAGLIDAGPARLLLHGLFSLIA
                     GRRGDHIAATAHLDVAEHYLVTTKAELENFDFVLAARALVAVQVGDLRRGYEELAPILQ
                     PGYAGMMLRHQWLPPLVRVAIKLGDWEKVEQAVEVLELEAAREPVPARAFCALHRCTAL
                     LTRDPEPGLVAAEHYRRVGRPIELASTLGDVAELFAERGLFSDARAAFAEAAAIFAEVG
                     AQWDLDSTSARLAELGM"
     misc_feature    complement(1400..1402)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4173..5189
                     /locus_tag="B9C43_RS21035"
                     /old_locus_tag="SAMN05661093_04288"
     CDS             4173..5189
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019322.5"
                     /locus_tag="B9C43_RS21035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04288"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_084428604.1"
                     /transl_table=11
                     /translation="MSLTLSEAAGAVQTGHGQPPALGLWSTADRGRTLVVHVPHKQNER
                     IADISVNENSRSVLVEVVRIGVPGDNGARLVRSTRSVPLAAPLGNRRLTMTWDGAKVPL
                     LQAVPAGGEDTQESAAERAKKELVTLIDTLEPGSALPSERVLSERLEIARMTLRHAVDE
                     LTLAGKVSRRRGSGTYVAESKLLCRITPDGLDLDPTSPGAGFGHVHVVRDVVEADEQVA
                     ADLGIDRRDLVLHIGRLLLVDHRPFGLVSRHIPIARLAETPGAPSALRWFSERTSRVDT
                     RIQLSTATPAEARLLDLSQVQPMLAWHKIALDDKDTPLERTRVLARGDRVVLDLSGQ"
     gene            complement(5504..6277)
                     /locus_tag="B9C43_RS21040"
                     /old_locus_tag="SAMN05661093_04290"
     CDS             complement(5504..6277)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="B9C43_RS21040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04290"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_160096616.1"
                     /transl_table=11
                     /translation="MAQWHEFVDPADVTERQRLALLEQVFDPISIRNIDRTGIKSSWSC
                     LEVGAGAGSIARALASRAREVVATDLTIDLLAPLSELGVKVLRHDVLVDDAPGTFDFIH
                     CRYVMEHLPARQTAIERMVSWLKPGGTLLIEGGAPTPELSSRPVVARAMEAALTIYGQG
                     LGSEPRWVRTLPQPLIAAGLRDCGAELCAPPVQGGTAMANWVSATMRLTDERAIAAGLI
                     TPEELASAHAAYRDPSFVDYTWLGIAAWGQKGETS"
     gene            complement(6238..6768)
                     /locus_tag="B9C43_RS21045"
                     /old_locus_tag="SAMN05661093_04291"
     CDS             complement(6238..6768)
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018627.5"
                     /locus_tag="B9C43_RS21045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04291"
                     /product="5' nucleotidase, NT5C type"
                     /protein_id="WP_084428606.1"
                     /transl_table=11
                     /translation="MESRSLDIGLDKAETWDWYQRQWGLNHDEFFALCSRGVRDGILFT
                     EGAPLPGAMRAVKRLARAGHRLHYITARAFNGVAASDAWHRTAEWLRKWTFPVHSLTVS
                     VDKNCRPTDVFLDDSPRVCHDLIAAGHPRPVWWSHFPTQTHPATTVSSWEEFHTIVEGE
                     AWLSGTSSLTQRT"
     gene            complement(6784..7149)
                     /locus_tag="B9C43_RS21050"
                     /old_locus_tag="SAMN05661093_04292"
     CDS             complement(6784..7149)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025161.5"
                     /locus_tag="B9C43_RS21050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04292"
                     /product="DUF4180 domain-containing protein"
                     /protein_id="WP_084428607.1"
                     /transl_table=11
                     /translation="MTDQLEHIEDVPVFVLGADGPALATENDALDLIVAAGHHGADAKW
                     AVVPASRLCSDFFTLSTGFAGMMAQKFTSYGVGLVILGDVSGYASKPFQDWVRETNKGR
                     HVWFARDKQHLAELLRG"
     misc_feature    complement(7142..7157)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.17"
                     /tool="antismash"
     gene            complement(7163..8998)
                     /gene="asnB"
                     /locus_tag="B9C43_RS21055"
                     /old_locus_tag="SAMN05661093_04293"
     CDS             complement(7163..8998)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154867.1"
                     /locus_tag="B9C43_RS21055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04293"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_084428608.1"
                     /sec_met_domain="GATase_7 (E-value: 1.1e-45, bitscore:
                     150.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 3.1e-78, bitscore:
                     259.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGITGWVSYSADLTTRQSVVDDMTATMSCRGPDASGTWVRRHVA
                     LGHCRLAIIDLPGGRQPMTVETPRGAVTLVYSGETYNFTELRRALEGLGHKFRTASDTE
                     VVLHGYLEWGADLASRLNGMYAFAIWDERDQKLVMVRDRLGIKPFYYYPTPDGVLFGSE
                     PKAILANPAMPRIVDMDGLRELVAFTQAPRWALWKGMYEVEPGQILTVSRSGIAAHTYW
                     RLEPQPHNDSLEDTVGTVRELLTDIVERQLVADVPRCVLLSGGLDSSAITGLASSFVGS
                     ELRTFSVDFIGREETFRADEARDTPDTPFIRDVVSMVNPQHKFVTLSSALLGDPELRRK
                     VIAARDMPIGFGEMDTSLYLLFESIRAESTVALSGESADEVFGGYRWFHDPLVVGTDNF
                     PWLVYHSAMSGDRAALMCPHLRGHLDIPGYMAAQYSDAVAAVEHLDSESALERRMRTIS
                     HLHLTRFVRMMLDRKDRISMAVGLEVRVPFCDHRLVEYVYNTPWSMKSFDGREKSLLRH
                     ATSHVVPGSVQARLKASYPSTQDPRYNTELQAQAKEVLADRDHLAMSLIDWDWLTDVIA
                     MDPASMPSNVRRGIDRVLDLYHWIDMYDPIIDRPD"
     gene            complement(9000..9992)
                     /locus_tag="B9C43_RS21060"
                     /old_locus_tag="SAMN05661093_04294"
     CDS             complement(9000..9992)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669510.1"
                     /locus_tag="B9C43_RS21060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04294"
                     /product="methyltransferase"
                     /protein_id="WP_084428609.1"
                     /transl_table=11
                     /translation="MQVDLKAATEAVELITGGWRAQCLYTAVKLGIPDLIEDGKTTNAQ
                     LAEATGAVEEGIHRLMRLLVAVGVFEGDGVRGYRNTPVSSVLLDDPDSLRDMCLLYGEE
                     FYTAWGHAVECITTLTAGFEIAYGSPLYTYLSQNPEATTRFQLAMKAGNLFFDYVPEVV
                     DLSGKTFVDVGGGPGQLTAAILSAVPDARAMLLDREHVIPVARKNLAAFDRVELFGGDM
                     FVAVPEGGDVYFLCRVLAGWSDDSIVGVFENCRKAMNPGGRLIILERVVVDSDSTMLPA
                     LWDLHLLMTNGGRHRTVEKFTSLLERAGLEVERVADLPVETTAIIARPR"
     misc_feature    complement(9969..9978)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(10001..10459)
                     /locus_tag="B9C43_RS21065"
                     /old_locus_tag="SAMN05661093_04295"
     CDS             complement(10001..10459)
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phenazine: phzB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669511.1"
                     /locus_tag="B9C43_RS21065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04295"
                     /product="PhzA/PhzB family protein"
                     /protein_id="WP_200825626.1"
                     /sec_met_domain="phzB (E-value: 3.2e-56, bitscore: 186.5,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDSELRRIHRAVVEDYLSRQGENRLTRYLLFTPDGSAGLYTGDT
                     EQPIVSTGHEKLKAHGEWSLRMFPDWVWFNVEIFETQDPNRFWAECDGEGKILYPSYPP
                     GHYRNHFIHSFELRDGRIAVQREFMNPFNQLRALGIEVPVINRGGIPT"
     gene            10563..11399
                     /locus_tag="B9C43_RS21070"
                     /old_locus_tag="SAMN05661093_04296"
     CDS             10563..11399
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028009.1"
                     /locus_tag="B9C43_RS21070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04296"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_084428610.1"
                     /transl_table=11
                     /translation="MHNYVVADVFTDTMLEGNPVAVFLDAEDIPPDRMQRIAGELNLSE
                     TVFVMPPEDGGDVRLRIFTPVNELPFAGHPTMGTAFVLGELTDKDSILLETRMGIVPFE
                     FDRVGGKVHRARMRQPIPEWRPYEKADHLLEALGLKTSTLPVEIYRNGPRHVFVGLPDV
                     AALSALRPDLLMLADHLDMAANCFAGAGTEWRMRMFSPAYGVAEDAATGSAAGPLAIHL
                     GRHDLVPFGTRIEIQQGVEMGRTSKMYAQVTGTPDQIDMVEVSGQAVVIARGTMLL"
     misc_feature    10959..10961
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11456..12715
                     /locus_tag="B9C43_RS21075"
                     /old_locus_tag="SAMN05661093_04297"
     CDS             11456..12715
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020416749.1"
                     /locus_tag="B9C43_RS21075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04297"
                     /product="serine hydrolase"
                     /protein_id="WP_084429116.1"
                     /transl_table=11
                     /translation="MTNSEIDKNSATSGSGDYVAEGWGKVADAFRANFDTNPGEVGAAC
                     CVYVDGRPVVDLWAGIADREANRPWDQNTIALVASTTKGATAICAHMLVQRGLLDLDAP
                     VAKYWPEFAANGKEQIPVRWVLSHQAGLPIVDGPLTFEEACAWDPVIRALEAQKPLWKP
                     GTEHIYHAATFGYLVGEIVRRITGKTLGTFFAEEVAGPLGLSAWIGLPEEHEPRVARIE
                     YAAPFTLEEMTAGLIEMTGLDADTVTAWMTALWTPGSPAALAGTLGGAFDPTMDINALR
                     AYRAAEIPAGNMLTDARSLARMYAATVSDVDGVRLLDPATVRQATEVHTDKTPMHGLPP
                     GLDLPADRTFNMSLGFWRACPPMPLTGPGSFGHPGAGGSIGFADPDAGVGFGYITNLWS
                     YRVGEPRATNLAEAVRSCLG"
     gene            complement(12856..13443)
                     /gene="phzG"
                     /locus_tag="B9C43_RS21080"
                     /old_locus_tag="SAMN05661093_04298"
     CDS             complement(12856..13443)
                     /EC_number="1.10.3.16"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene="phzG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669513.1"
                     /locus_tag="B9C43_RS21080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04298"
                     /product="phenazine biosynthesis FMN-dependent oxidase
                     PhzG"
                     /protein_id="WP_200825627.1"
                     /transl_table=11
                     /translation="MNEFDQPPADPIALFGAWFDAAKQTVREPGVVALATANAEGVVSN
                     RIVQTIKVTDTGWVFTSHAGSQKGQDIAATGWASGVFYWRETSRQLIIAGPVTRLSDAD
                     CDELWFARHPSTHPMSVAAEQSAPLEDEEALRARAQQLADGGQTLARPSAWLGYELVPS
                     IVEFWQGSPDRLHRRLRYYRNGNGWTSRRLQP"
     misc_feature    complement(12865..12867)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13440..13763)
                     /locus_tag="B9C43_RS21085"
                     /old_locus_tag="SAMN05661093_04299"
     CDS             complement(13440..13763)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) thio_amide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669514.1"
                     /locus_tag="B9C43_RS21085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04299"
                     /product="hypothetical protein"
                     /protein_id="WP_033392265.1"
                     /sec_met_domain="thio_amide (E-value: 1.5e-18, bitscore:
                     62.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKATIAWWDLSRSTQTIDSLRDYLRSEGVKPWADVPGLRLKFWIA
                     DRAGNRWGAVMLWETAPGPDQPLPPHKAAELIGYPPTERIRFDVEACIEGVFAEPSLSL
                     ELL"
     misc_feature    complement(13560..13562)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13760..15598)
                     /locus_tag="B9C43_RS21090"
                     /old_locus_tag="SAMN05661093_04300"
     CDS             complement(13760..15598)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681620.1"
                     /locus_tag="B9C43_RS21090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04300"
                     /product="anthranilate synthase family protein"
                     /protein_id="WP_084428612.1"
                     /transl_table=11
                     /translation="MDLLDRVLAADPPPFALLHRPATIGHDRLDVLVGEMSTPDTLADV
                     PLDPDSEPGQEVLVVVPYRQIAERGFDCLDDGSPLIAMRVTEQAVLPVHEVLARIPVVP
                     IKLADGYFDVDDEIYADTVRTIIEDEIGEGTGANFVIKRSYIANITGYRAASALTFFRR
                     LCERESGAYWTFIVHTGTHTFIGATPERHVSLHDGVAVMNPISGTYRYPPTGPTLAGLM
                     EFLSDTKENDELHMVVDEELKMMARICAEGGRVVGPFLKEMARLAHTEYFISGRSTRDP
                     RQILWETMFAPTVTGSPLESACRVISRYEQGGRGYYSGVLALIGRNPGGSRAMDSAIMI
                     RTADIEHTGRVKISVGATLVRHSDPLSEVEETRAKAAGLLAAFDAGKRNQFSDDPDVRT
                     ALKQRTIGLADFWLDGTPIPLPDPGLHGLEVLVVDAEDTFTAMIAHQLRSLGLCVRVKR
                     FDEPYTWDNADLVVMGPGPGDPLDMAHPRIAHLHNAIAGLLTERRKFVAVCLSHQVLSR
                     QLGLNVHRCAVSNQGTQRQIDLFGAREVVGFYNAFAARSDEDKVGEVEICRDATTGEVH
                     ALRGPHFSSMQFHAESVLTLDGPRILATRIKEVLAL"
     gene            complement(15598..16221)
                     /locus_tag="B9C43_RS21095"
                     /old_locus_tag="SAMN05661093_04301"
     CDS             complement(15598..16221)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609610.1"
                     /locus_tag="B9C43_RS21095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04301"
                     /product="isochorismatase family protein"
                     /protein_id="WP_084428613.1"
                     /transl_table=11
                     /translation="MVGIPAIAPYPLPAIADLPPNTATWTTDPARAVLLIHDMQRYFLR
                     PFPESVAHQLIGNIAVLVDRCRELRVPVAYTAQPGGMTARQRGLLKDFWGPGMRVDPVD
                     REVVEPLAPDAEDWIFTKWRYSAFHRSNLLARMREEGRDQLIVCGVYAHVGVLMSAVDA
                     FTNDIQAFVVADAIADFTPEYHRMAITYAAERCAVVLTTKEVLP"
     gene            complement(16235..17224)
                     /locus_tag="B9C43_RS21100"
                     /old_locus_tag="SAMN05661093_04302"
     CDS             complement(16235..17224)
                     /codon_start=1
                     /gene_functions="regulatory (extras) StrR_like: StrR-like
                     pathway specfic regulators"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636716.1"
                     /locus_tag="B9C43_RS21100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04302"
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="WP_084428614.1"
                     /transl_table=11
                     /translation="MTNFAAVSLPREEFDCLDGNSGASPVVRVPTRALRVAGSPRIAGE
                     NLEHVRALADAPDELPPIIVHRQTMRVIDGVHRLRAAKLRNQHDIAVRFFDGDEADAFV
                     LAVRANVAHGLPLSLAERKAAAKSIVMSHPHWSDRLIASVTGLSAKTIGEVRRNGKVPQ
                     PESRIGQDGRVRPINSLEKRRLAMNLMRQNPNLSLRQVAKAAGISPETARAVRARLQRG
                     EDPTVRKPSNIKKVEERRQPQARAPQPLPLPDRVTIMRYLRTDPTLRFSETGRTLLRLL
                     DVHAMSNDRWALLVRNVPPHARGTIAQAALECARVWRTVAEQLERTAP"
     misc_feature    17618..17632
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.68"
                     /tool="antismash"
     gene            complement(17623..18219)
                     /locus_tag="B9C43_RS21105"
                     /old_locus_tag="SAMN05661093_04303"
     CDS             complement(17623..18219)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632740.1"
                     /locus_tag="B9C43_RS21105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04303"
                     /product="copper resistance CopC family protein"
                     /protein_id="WP_143446487.1"
                     /transl_table=11
                     /translation="MSAALLLSATALLVTAAPALAHTSLKSSNPAKNASVATPPTQIQL
                     TFSEPVQVEPGAISVAGPTGAQWTVGQVTVANEVVTAPVTPVGPAGQYTINYRVISADG
                     DPVSGKVPFTLTAAVAAPTTTTPTTTTAPPTTTSTAQQGQNGSAVTTATPAPAAQENED
                     SGGLPVWVWIVGAIVVVGAGVFAGLRFGKGGTEKS"
     misc_feature    complement(19295..19309)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(20354..20369)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
ORIGIN
        1 aacagcggga tcaggccgac gtgcaggtgc tgtcgaccga gcgggtgggc ccggaagcgt
       61 tggcacggtt gaggaattcg gcagccgacg gggggctgcc gactgtcctg atgaccggcg
      121 agcttggcga ggcgccactg ctgactctgg tcgagtgcca cgtcgtcgcg atactgccga
      181 agaactccgt caccggagac cagttggtcg actgcatcgt ggccgctgcc gcaggcaacg
      241 gcgtcatgcc ccgcgatgta ctcggcaccc tgctgcgccg gatcaaggtg ctgcagcagg
      301 aagtgctggc tcccaacggg ttgagcgcgt ccggcctcga acctcgtgag gtggacgtgc
      361 tgcggctgat cgcggaaggc tggggcactg aggagatcgc caaggaactg gcgtactccg
      421 agcggaccgt gaagaacgtc atcttcaaca tgacgagccg gctgcacctg cgcaacaggg
      481 cacacgcggt ggcttacgcc ctacgagcgg gtgtcatcta gatgcggcaa gggccgtggc
      541 gtcacatgcc gagctcggcc agtctggccg acgtggagtc caggtcccat tgggccccga
      601 cttccgcgaa gatcgccgcg gcctcggcaa aggcggcgcg ggcatcggag aagagcccgc
      661 gttcggcgaa cagttcggcg acgtcgccga gtgtcgacgc cagctcgatc ggcctgccca
      721 cccgccgata gtgctccgcc gcgaccagcc ccggctcggg atcgcgcgtg agcaacgcgg
      781 tacatcggtg cagcgcgcag aaagcccgcg cgggcacagg ttccctggcg gcctccagct
      841 cgagcacctc gacggcctgc tcgaccttct cccagtcgcc cagtttgatg gcgactcgaa
      901 ccagcggcgg cagccactgg tggcgcagca tcatcccggc gtaacccggt tgcaggatcg
      961 gcgcaagttc ctcgtacccc cgtcgcaagt ccccgacttg gacagcgacg agcgcgcgtg
     1021 cggccaggac gaaatcgaag ttctccaact ccgccttggt ggtcacgaga tagtgctcgg
     1081 ccacgtccag gtgggcggtt gccgcgatgt gatcgccacg gcgtccggcg atcaacgaga
     1141 acagcccgtg cagcaacaac ctcgccggtc ccgcgtcgat cagaccggcg tacgtgatcg
     1201 tcggcccgtc gccggtgatg gtggtgagcg cctgcagcgc ctcgtcccac cggccccgcc
     1261 agtaatggtg caccgcggcg gtcacgtgca gtccgatcgg cagtccgttc accgggcaga
     1321 tgtcggccgc cacacccagg gtggcgtcgg cttcgtccag ccggtcgagg ttctgcagcg
     1381 tgtagatctt gttgtccagt aagtcgtact gcattccgac gtactctttg cgttcccgca
     1441 caaggtcgat cgcctcgtcc acgtgccgca gcgccgcgag gtggtcgcgg cgcatcgagt
     1501 cgaccagcca cctggtctgc aaggcgtgcg ccgcgtagaa gctgtcaccc gccgtgatcg
     1561 cttcctcgta agcgtccttg gccgcgatct cggcggtgtc gatgttgctc atgtcgcgcc
     1621 gcaggtacgc cagcaaagcc cggtgccgca gccgccactg ctccggcaac gccggatcca
     1681 ccggtacctc ggtcaggatc gagatcgcct cgacccgtct gccctgccgg tacacgatcg
     1741 ccgcgagcag ctgccggacc tcagccgcca gcaccggatc ggtgcagatc gccagcgcgt
     1801 gccgcgcctt cgcttccggg tcacgggaga gctggaacag cacccgcacc tcgatcgcct
     1861 ggagcacttc gcggttcggg tcgccgatgt ccaaggtgtc gatcacttgc gcgagcagtt
     1921 ccgcggcgac ctgcggagcg cgcccggcga gctcggcgac gtgctcggcc agccacccgg
     1981 ccacccacgg ctcgacgtac ccgcccgcgg cgaccaactg ctcggacacg cggtgcggcg
     2041 gtgcgcccgc ttcggcgagc accttggcag cctgccggtg cagcacaccc cgggtgggcc
     2101 ccgcgatgcc gccgtagacg gtgtcacgca tgagctggtg gcggaaggtg agtttcgggc
     2161 cttcctcgac gaggacgttc gcgttcaccg cgtcggtcac cgcgcgcacg agataccaca
     2221 ccggccgctc ggaaaccgcg gcgatgttgc cgatcgtggc ctcggggccg agcacggcca
     2281 cccagacaag catctctttc gtgctgtcgg acaacgactt tgacgatcgt tcgaccgcgg
     2341 cgacgagcga gcgcggcgcg tcctccgctt tggactcgtc gatgtaggcg acgccgtcga
     2401 tcatttccac cgcgccgtcg agcagcagtg cgttcacgac ttcccgcatg tacaacgggt
     2461 ttccgtcggc gcgggaggtg atccggcgca gcacccggcc agggcgcgcg ccgaccagct
     2521 cggtcagcag cgcttcactc tccacaaagg agagcggccg catcgcgatc gcggtgcctc
     2581 gttccgcacc gctttcgatg tagcgccgca gctcggtcag ctccgcccgg ccgtgaccgg
     2641 tgttggccgc gcagatcaac agcagcggca agcggttcgt tgcctcgcat agccttcgcc
     2701 acgtctgcac ggtgtcttcg tcggcccatt ggatgtcgtc gagcacgagg acgagcggcc
     2761 cggtcgcgca aattcgttcg atcatcgaac caactgattc accctgcggc agcttgcggc
     2821 ccattcccag gcattccagc atgatctgca gcgggaaccg gccggccagc tcgtcggcca
     2881 cggcccagcc gacctgcacg gcgttgatgt cgacgtccgc cagcgcggca ccgagcagtg
     2941 cggacttgcc gatgcccggc tcgccctcga tccagatcgc tccgccggca ccctgggaca
     3001 caccggcgag tcgctcacgg acttgttcga gttccgcgcg cctgccgaca aacggccggt
     3061 ccttgtcccg cgccgcgctg cacggccgga catcgagccg tggcgtgtcc ggctcggcct
     3121 ggaacatctc gttgcccgcc aagacatcgg cgtgcacctg gcacaacgcc gggcctggat
     3181 gcgctcccag ctcccgcaac aaggtcgcgc gcgcgtcggc gaacacgtca agcgcctccg
     3241 cgtgcctgcc gctgcgggcc agtgcgatca tcagcagttc ccgcaacgac tcccgcagtg
     3301 gatggtcacg aaccaggact tccaggtccg cggcgacctc gacgtggtcg cccagttcca
     3361 gccgtgcccg ggcgaacgtc tcgaccgcgc gcagcctggc ctgttccaac ctggtgcgtt
     3421 cctgctcggc gaaaggtcct ggcacaccgg cgaacgcctc gccgcgccac aacaccagtg
     3481 cctcgccgag cttttcggtc acgccacggt ggtctccccg tgccgccaac gcgttcgcct
     3541 gctcgcagag ctcgtcgaac agcgtgacgt ccacctgctg ggagtccaca cgcaacgagt
     3601 aaccgtttcc tgaggacaca atgagttcac ggccgaggtc gccgagtgtc cgccgcaggc
     3661 cggacatgta ggtgtagacg ctgccgtcgg cgctggcagg cgcggagcgg ccccacaccg
     3721 cttcgaccag ctcagcccgg gacaccgtct gcccggaccg catcgccagg acaacgaaaa
     3781 ctgcccgttg ccgagcgggc ccgagcccga tctccacgtc ggcgttgacc accctgaccg
     3841 ggccaagcaa ctcgaccctt ggcgcggtac gccgaccttg ctcccccagt gcactcgctt
     3901 cgatcccgag aggcacaagg tcaaccctac cccaggttga tcgggccttt cttttcgcag
     3961 tttcaatggc acaactgaag cacctttaaa ccgttccgca ccaacaagat catttacagt
     4021 tgaccgcggc tttacccatt tctcttgtcc ataatggaca aattcgttgt ttcgcgcacg
     4081 gctgtagagt ctttcgggca agagtgatcc ttccgcgggc ctggtcaggt aatcctgtgc
     4141 tgagtagtcc tcaggtcccc caaggagttc ccgtgtcgct cactctctcc gaagcagcgg
     4201 gtgcggtgca gacaggccac ggccagccgc ccgcgctcgg cctgtggtcg accgccgacc
     4261 gtggccgcac actcgtcgtg cacgtcccgc acaagcagaa cgagcggatc gccgatatct
     4321 cagtcaatga gaactcacgc tcggtgctcg tcgaagtggt ccggatcggc gtgccaggag
     4381 acaacggcgc gagactggtc cgctcgaccc ggagcgtgcc gctcgccgcg ccccttggca
     4441 accgcaggct cacgatgacc tgggacggcg ccaaggtgcc gttgctgcag gcagtcccgg
     4501 cgggcggaga ggacacgcag gagtcggcgg ccgagcgcgc gaagaaagag ttggtcacgc
     4561 tgatcgacac ccttgaacca gggtcagcgc tgccatcgga gcgggtgctc tcggaaaggc
     4621 tggagatcgc ccggatgacg ctcaggcacg cggtcgacga gctgacgctg gccggaaagg
     4681 tgtcacgccg ccggggaagc gggacctacg tggcggagtc gaagctgctc tgccggatca
     4741 ccccggacgg cctcgacctc gacccgacgt cgccgggagc cggcttcggc cacgtgcacg
     4801 tggtccggga cgtggtggaa gcggacgagc aggtggcagc ggacctcgga atcgaccggc
     4861 gggatctggt actgcacatc ggcaggctgt tgctggtcga ccacaggcca ttcggactgg
     4921 tgtcgcgcca catcccgatc gcccggctgg cagaaacccc aggagcgccg agcgcgttgc
     4981 ggtggttctc ggagcgcacg tccagggtgg acacgcggat ccagctgtcg acggcgacgc
     5041 cggcggaggc gaggctgctg gacttgagcc aggtccagcc catgctcgcc tggcacaaga
     5101 tcgcgttgga cgacaaggac acgccgttgg agcggacgcg ggtgctggct cggggtgacc
     5161 gggttgtcct cgacctttcg gggcagtaag agctgggaac gtttccatgg acggtccact
     5221 gtgtacgtag tggctggggt ggcgggcaca gtggaccgga ccacggatga cggcttcacg
     5281 ccaggcgata ggcgaatatt tccggcaaat tgaacacgtg agctaacaat ttctcgcgtt
     5341 cacctgaaac ccggaacatt cgaaagccac aacgccacga catagcacac gtaggcgccg
     5401 gcgccgccga agaaagcagc cagaaaccct gccggaccaa atccatggcc gtgtggctct
     5461 ccagcacgcc tgccaatcgg accgtcatct cgggttcccc gtgctaggag gtttcacctt
     5521 tctggcccca tgccgcaatg ccgagccatg tgtagtccac aaaggatgga tcgcggtagg
     5581 cggcgtgcgc cgatgccagt tcttcggggg tgatcagtcc cgcggcgatg gctcgttcgt
     5641 ccgtcagtcg cattgtggcg cttacccaat tggccatcgc tgtaccgcct tggactggtg
     5701 gggcgcagag ttcggcgccg cagtcgcgca gaccggcggc tatcaacggc tgcggaagtg
     5761 tgcgcaccca acggggttct gagcccaggc cttggccgta gattgtcagc gcggcttcca
     5821 tggcgcgggc gaccactggg cggctggaga gttccggggt tggggcgccg ccttcgatca
     5881 gcagtgttcc gcctggtttg agccaggaca ccattcgctc tatcgctgtc tgcctggccg
     5941 gcaggtgttc catcacgtac cggcagtgga tgaagtcgaa tgtccccggt gcgtcgtcga
     6001 ccaggacgtc gtggcgcagg actttgactc ccagctccga caggggcgcc agcaagtcga
     6061 tcgtcagatc ggtggcgacc acctcacgcg cccgcgacgc cagcgctcgg gcgatcgagc
     6121 ccgctcccgc gccgacttcc aggcacgacc acgacgactt gattcctgtt ctgtctatgt
     6181 tccggatgct gatggggtcg aagacctgct caagcagggc cagccgctgc cgctccgtca
     6241 cgtccgctgg gtcaacgaac tcgtgccact gagccacgct tctccctcga cgatggtgtg
     6301 gaactcctcc caggaggaca ccgtagtggc gggatgggtc tgggtgggga aatgcgacca
     6361 ccacaccggg cgcgggtggc ccgcggcgat caggtcgtgg cagacgcgcg gggagtcgtc
     6421 gaggaagaca tccgttggac ggcagttctt gtccaccgac accgtcagcg agtgcaccgg
     6481 gaaggtccac ttccgcagcc attcggctgt ccgatgccac gcgtcggagg cggccacgcc
     6541 gttgaacgcg cgtgcggtga tgtagtgcag ccgatggccg gcacgtgcga gccgcttgac
     6601 ggcccgcatc gcaccgggca aaggcgcacc ctcggtgaag aggatgccgt cacgtacacc
     6661 gcggctgcag agggcgaaaa actcgtcgtg gttgaggccc cactgccgct ggtaccagtc
     6721 ccacgtctcg gctttgtcga ggcctatgtc gagtgagcgg gactccatgc gctcatggtc
     6781 gcctcagccg cgcaacagct ccgcaaggtg ctgcttgtcc cgggcgaacc agacgtgccg
     6841 tcccttgttg gtctcacgga cccagtcctg gaagggcttg ctggcgtagc cggagacgtc
     6901 gccgaggatc accaggccca cgccgtagct ggtgaacttc tgcgccatca tcccggcgaa
     6961 cccggtgctc aacgtgaaga aatccgaaca cagcctgctg gcaggaacaa ccgcccactt
     7021 ggcgtccgcg ccgtggtgcc cagcggcgac gatgaggtcc agcgcgtcgt tctcggtggc
     7081 cagggccggg ccgtcggcgc cgagaacgaa aacaggaaca tcctctatgt gttcgagttg
     7141 atcggtcacg ctttcgatcg tactaatcgg ggcgatcgat tatcgggtcg tacatgtcga
     7201 tccagtggta cagatccagg acccggtcga tgccccgccg gacgttgctc ggcatcgaag
     7261 ccgggtccat ggcgatcacg tcggtcagcc agtcccagtc gatcagggac atcgccaggt
     7321 ggtcgcggtc ggcgaggacc tccttggcct gcgcctggag ttcggtgttg taccggggat
     7381 cctgcgtcga cgggtaggaa gccttcaacc gcgcctgcac cgaaccgggc acgacgtgcg
     7441 acgtggcgtg ccgcagcagg ctcttttccc tgccgtcgaa ggacttcatc gaccacggtg
     7501 tgttgtagac gtactcgacc agccggtgat cgcagaacgg cacgcgcact tccaggccga
     7561 cggccatcga gatccggtcc ttgcggtcga gcatcatccg gacgaaccgg gtcaggtgca
     7621 ggtgtgagat ggtccgcatc cggcgttcca aggcagactc ggagtcgagg tgttccacgg
     7681 cggcaacggc atccgagtac tgcgcagcca tgtacccggg gatatccagg tgaccgcgca
     7741 gatgcgggca catcaaggct gcccggtccc cgctcatcgc actgtggtag accagccaag
     7801 ggaagttgtc cgtaccgacc acgagtggat cgtggaacca ccggtagccg ccgaagacct
     7861 cgtcggccga ctctccggac agggccacag tggactcggc cctgatcgac tcgaacagca
     7921 ggtacagcga ggtgtccatc tcgccgaacc cgatgggcat gtcacgggcc gcgatcactt
     7981 tgcggcgcag ctccgggtcg cccagcaggg ccgacgacag ggtcacgaac ttgtgctgcg
     8041 ggttgaccat cgacacgacg tcacggatga acggcgtgtc cggggtgtca cgggcctcgt
     8101 cggcacggaa ggtctcttca cggccgatga agtcgaccga gaaggtgcgc agctccgagc
     8161 ccacaaagga cgatgccaaa ccggtgatgg cactggaatc caagcctccg gacagcagga
     8221 cgcaccgcgg cacgtcggcc accaactgcc gttcgacaat gtcggtcagc agctcccgca
     8281 cagtgcctac tgtgtcctca agggaatcgt tgtgtggctg gggttcgagc cgccagtacg
     8341 tgtgcgccgc gatccccgag cgagacacag tcaggatctg gccgggctcg acctcgtaca
     8401 tccccttcca caacgcccaa cgcggtgcct gcgtgaatgc gaccagttcg cgcaggccgt
     8461 ccatgtcgac gatccgcggc atggccgggt tggccagaat cgccttgggc tccgatccga
     8521 acaggacacc gtcgggcgtc ggatagtagt agaaaggctt gatgcccagg cggtcccgga
     8581 ccatcaccag cttctggtca cgttcgtccc agatcgcgaa ggcgtacatc ccgttcagcc
     8641 gtgaggccag atcggcgccc cactcaagat agccgtgcag cacgacctcg gtgtcgctgg
     8701 cagtgcggaa cttgtgcccc aagccttcca gagcacgacg cagttcggtg aagttgtacg
     8761 tctcaccgct gtacaccagc gtcacggcac cgcgaggagt ttccacggtc atcggctgcc
     8821 ggccaccggg aaggtcgatg atcgccagcc ggcagtgccc gagagccaca tgccgacgca
     8881 cccacgttcc cgacgcatcg gggccacggc aggacatcgt ggcagtcatg tcgtccacaa
     8941 cggactggcg ggtggtgagg tcggcggagt acgagaccca gcccgtgatg ccgcacatgt
     9001 caacgcggcc tggcgatgat ggcggtggtc tccacgggca ggtccgcgac ccgctcgacc
     9061 tcaagaccgg cccgctccag caacgacgtg aacttctcga ccgtccggtg cctgccgccg
     9121 ttggtcatca gcaggtggag gtcccacaac gcgggcaaca tcgtggagtc cgagtccacg
     9181 acgacacgct ccaggatgat caagcgtcca cccgggttca tcgctttgcg gcagttctcg
     9241 aagactccca cgatcgagtc gtcgctccac ccggccagca cgcggcacag gaagtacacg
     9301 tccccgcctt cggggaccgc cacgaacatg tccccaccga acagctcgac ccggtcgaag
     9361 gccgccaaat tcttccgtgc caccgggatc acgtgctcac ggtcgagcaa catggctcgc
     9421 gcgtccggca ccgcggacag gatcgccgcg gtcagctggc cgggtccgcc accgacgtcc
     9481 acaaaggtct tcccggacag gtcgacgacc tcggggacat agtcgaagaa caggttgccc
     9541 gctttcatcg cgagctggaa acgcgttgtg gcttctgggt tctgactgag gtatgtgtac
     9601 agcggggaac cgtaggcgat ctcgaagccg gcggtcagtg tggtgatgca ctcgacggcg
     9661 tggccccagg cggtgtagaa ctcctcgccg tacaacaggc acatgtcacg cagcgagtcc
     9721 ggatcgtcca gcagcaccga actcaccggg gtgttgcggt atccccggac gccgtcgccc
     9781 tcgaacacac cgaccgcgac cagcaggcgc atcagccggt gaatgccttc ctccacagcg
     9841 cctgtcgctt cggccagctg ggcgttcgtg gtcttgccgt cctcgatcag gtcggggatg
     9901 ccgagtttga ccgccgtgta caggcactgc gcgcgccagc cgccggtgat cagttcgacg
     9961 gcctcggtgg ccgccttcaa gtcgacctgc acaacaactc ctaggtgggg atgccgccgc
    10021 gattgatcac cggtacctcg atgcccagcg ccctgagctg gttgaacggg ttcatgaact
    10081 cccgctggac ggcgatccgg ccgtcccgca gctcgaagga gtggatgaag tggttgcggt
    10141 agtgcccagg cgggtaggac gggtagagga tcttgccttc gccgtcgcac tcggcccaga
    10201 accggttcgg gtcctgggtt tcgaagatct cgacgttgaa ccagacccag tcggggaaca
    10261 tccgcagcga ccattcgccg tgtgccttga gcttctcgtg gccggtggac acgatcggct
    10321 gctcggtgtc ccctgtgtac agtccggcgc tgccgtccgg ggtgaagagc aggtagcggg
    10381 tcagccggtt ctcgccctgc ctgctcaggt agtcctcgac gaccgcgcga tggatccgcc
    10441 gcagctcact gtcattcatt tcggacctcc ggaatattgg taacgactgg cccgggaaat
    10501 tgtcaaaccg tgtccaacca cggagttgga cacagcgctg accgcgaagc tagcgtcgaa
    10561 gaatgcacaa ctatgtggtc gccgacgtat tcaccgacac gatgctcgaa ggcaacccgg
    10621 ttgccgtttt cctggacgcg gaggacattc cgccggaccg gatgcaacgc atcgcaggcg
    10681 agctcaacct ttccgagacg gtgttcgtca tgcccccgga agacggtggt gacgtgcggc
    10741 ttcggatctt cacgccggtc aacgagctgc ccttcgccgg ccacccgacg atgggcacgg
    10801 cgtttgtcct cggcgagctg accgacaagg acagcattct gcttgaaacc cggatgggca
    10861 ttgttccgtt tgaattcgac cgcgtcggcg gaaaggtgca ccgggcacga atgcggcagc
    10921 ccattccgga gtggcggccg tacgaaaaag ccgatcactt actcgaggca ctgggcttga
    10981 aaacatcgac tctgccggtc gagatatacc ggaacggacc gaggcacgtg ttcgtcggcc
    11041 tgcccgacgt cgcggcgctg tccgcgctgc ggcccgacct gctgatgctg gccgaccact
    11101 tggacatggc ggcgaactgc ttcgccggtg cggggaccga gtggcggatg cgcatgttct
    11161 cccctgcgta cggggtggcc gaggacgcgg cgaccggatc agcggccgga ccgctggcga
    11221 ttcacctcgg gcggcacgac ctggtgccgt tcgggaccag gatcgagatc cagcaaggcg
    11281 tcgagatggg ccggacctcg aagatgtacg cccaggtgac cggcacaccg gaccagatcg
    11341 acatggtcga ggtctccggt caggccgtgg tcatcgcacg cggaacaatg ctgctctgac
    11401 accgtgtcag cgccgtgact gcccggcgtc agggcggtcc gtgatcgtca tcgccatgac
    11461 gaattcagag atcgacaaga acagcgcgac gagcggatcc ggtgactatg tcgcggaagg
    11521 ctggggcaag gtcgccgacg cgttccgcgc gaacttcgac accaaccccg gcgaggtcgg
    11581 cgcggcgtgc tgcgtctacg tggacggacg gccggtcgtc gacctgtggg caggcattgc
    11641 cgatcgcgaa gcgaaccggc cgtgggatca gaacaccatc gccttggtcg cgtccacaac
    11701 gaaaggcgcc accgcgatct gcgcgcacat gttggtgcag cgtggtttgc tggatctgga
    11761 cgccccggtg gccaagtact ggccggagtt cgccgccaac ggcaaggaac agatcccggt
    11821 gcgctgggtg ctttcgcacc aagccggtct gccgatcgtc gacggtccgt tgacgttcga
    11881 agaggcgtgc gcctgggacc ccgtcatccg tgcactcgaa gcgcagaaac cgctgtggaa
    11941 gccaggaaca gagcacatct accacgccgc gacgttcgga tacctggtcg gcgagatcgt
    12001 gcgtcggatc accggcaaga cactcggcac gttcttcgcc gaggaggtcg ctggtccgct
    12061 cgggctgagc gcctggatcg ggttgcccga ggaacacgag ccacgggtgg cccggatcga
    12121 gtacgccgcg ccgttcaccc ttgaggagat gaccgccgga ctgatcgaga tgaccggcct
    12181 ggacgcggac acggttaccg cgtggatgac cgccctgtgg actccgggct cgcctgccgc
    12241 cctcgccggc acactgggcg gtgccttcga tcccacaatg gacatcaacg cgctgcgcgc
    12301 ataccgtgcg gccgagatcc cagctgggaa catgctcacg gacgcacgct cgttggcacg
    12361 gatgtacgcc gccacggtca gcgacgtcga cggagtgcgg ctgctcgatc cggcgacggt
    12421 caggcaggcg acggaggtcc acaccgacaa gacgccgatg catggactgc cgccggggct
    12481 ggatcttccg gcggaccgca cgttcaacat gtcgctgggg ttctggcggg cctgcccgcc
    12541 gatgccgttg accgggccgg ggtcgttcgg ccacccgggc gcgggcgggt cgatcggctt
    12601 cgcggacccc gatgccggcg tcgggttcgg ctacatcacg aacctctggt cctaccgagt
    12661 cggcgaaccg cgggcgacga acctggccga ggctgtccga tcctgcctcg gctgacggag
    12721 tgcctagcct gggacggcgg gccgggtcgg tgcccttgcg gcgggcgagc agccagtgcc
    12781 cgcgcccagg ctgccagccg atccggttcg cgacccactt ccgctgcccg tgcgagcacg
    12841 acaggtttca ccgaactagg gctgtaaccg gcggctcgtc catccgttgc cgttgcggta
    12901 gtagcgcagc cgcctgtgca gccggtccgg gctgccctgc cagaactcca caatggacgg
    12961 gaccagctcg tagcccagcc aggccgatgg ccgcgcaagc gtttgcccgc cgtcggccag
    13021 ttgctgggca cgagcgcgca aagcctcttc atcctcaagc ggcgcactct gctcggccgc
    13081 caccgacatc gggtgggtgc tgggatggcg ggcgaaccac agttcgtcgc agtccgcatc
    13141 ggacaggcgg gtcactggcc cggcgatgat cagctgcctg cttgtctcgc gccagtagaa
    13201 caccccggag gcccacccgg tcgcggcgat gtcctggcct ttctggctgc ccgcgtggct
    13261 ggtgaacacc cagccggtgt ccgtgacctt gatcgtctgc acgatccggt tggacaccac
    13321 gccctcggcg ttcgccgtgg ccagggcgac cacgccgggt tcacggacgg tctgtttggc
    13381 cgcgtcgaac caggcaccga acaacgcgat cgggtcagcg ggtggctggt cgaactcgtt
    13441 cacaacagct ccagtgaaag cgagggctcg gcgaaaacgc cttcgatgca ggcctcgacg
    13501 tcgaaccgga tccgctcggt cggcgggtag ccgatcaact cggccgcctt gtgcggcggt
    13561 aacggctggt cagggccggg tgcggtctcc cagagcatga ccgcgcccca cctgttgccc
    13621 gcccggtcgg cgatccagaa cttcagccgc agcccgggca cgtcggccca cggcttgacg
    13681 ccttcggagc gcaggtaatc ccgcaaggag tcaatggtct gggtggagcg gctgagatcc
    13741 caccacgcga tcgtggcctt cacagagcaa gcacctcctt gatccgggtg gcgaggatgc
    13801 gcggcccatc gagggtgagc acggactcgg cgtggaactg catcgacgag aagtgcgggc
    13861 cgcgcaaggc atgcacctca cccgtggtgg cgtctcggca aatctccacc tcgccgactt
    13921 tgtcctcgtc actgcgtgcg gcgaaggcgt tgtagaaccc gacgacctcc cgggcaccga
    13981 acaggtcgat ctggcgttgg gtgccctgat tggacaccgc acaccggtgg acgttcagcc
    14041 cgagctggcg gctgagcacc tgatggctca ggcagaccgc gacgaacttg cggcgttcgg
    14101 tcagcaaccc ggcgatcgcg ttgtgcaggt gggcgatccg cggatgcgcc atgtccaagg
    14161 ggtccccggg acccggcccc atcaccacga ggtccgcgtt gtcccatgtg tacggttcgt
    14221 cgaaccgctt gacccgcacg caaagaccga gcgaccgcag ctggtgcgcg atcatcgcgg
    14281 tgaaggtgtc ctcggcgtcg acaacgagca cttcgaggcc atgcagaccg ggatcgggca
    14341 gtgggatcgg cgtcccgtcg agccagaagt ccgccaggcc gattgtccgt tgcttcagtg
    14401 cggtccgcac gtcaggatcg tcgctgaact ggttgcgttt cccggcatcg aacgcggcca
    14461 gcagcccggc cgccttggcc cgtgtctcct ccacttcgga cagtgggtcc gagtgccgga
    14521 caagggtcgc gcccacgctg atcttgacgc ggccggtgtg ttcgatgtcc gccgtcctga
    14581 tcatgatcgc cgagtccatc gcccgtgagc cgccgggatt gcggccgatc aacgcgagga
    14641 caccgctgta gtagccgcgg ccgccctgct cgtacctgct gatcacgcgg cacgcgctct
    14701 ccagcgggct gccggtcacg gtcggcgcga acatcgtctc ccacaggatc tggcgtggat
    14761 cacgcgtcga ccggccggag atgaagtact cggtgtgcgc gagccgagcc atttccttca
    14821 ggaacgggcc gacgacccgg cctccctcag cacagatgcg ggccatcatc ttgagttcct
    14881 cgtcgacgac catgtgcagc tcgtcgtttt ccttggtgtc gctgaggaac tccatcagac
    14941 cggcgagcgt cggcccagtc ggcgggtatc ggtacgtgcc gctaatcggg ttcatcaccg
    15001 cgacaccgtc gtgcaggctg acgtgccgtt ccggcgtggc accgatgaaa gtgtgcgttc
    15061 cggtgtggac gatgaaggtc cagtacgctc cggactcgcg ttcgcagagc ctgcggaaga
    15121 aggtcagcgc gctggccgca cggtatccgg tgatgttggc aatgtacgac cgtttgatga
    15181 cgaagttggc gccggtgcct tcgccgatct cgtcctcgat gatcgtccgg accgtatcgg
    15241 cgtatatctc gtcgtcgacg tcgaaatacc cgtcagcgag tttgatcggc acaacgggaa
    15301 tccgcgcgag cacctcgtgc acagggagca cggcctgttc ggtcacccgc atcgcgatca
    15361 gtggcgaacc gtcgtccaag cagtcgaagc cacgctcagc gatctgccgg tacggcacga
    15421 ccacaaggac ttcctgacca ggttcggagt cggggtccag cgggacgtcg gcaagggtgt
    15481 ccggtgtgga catttcaccg accaggacgt ccagccggtc gtggccgatg gtggcgggcc
    15541 ggtgcagcag cgcgaaaggt ggcggatcgg ccgccagcac ccggtcgagc aggtccatta
    15601 cggcaggacc tccttggtgg tcaacacgac cgcacagcgc tcggcggcgt acgtgatcgc
    15661 catccggtgg tactcgggcg tgaagtcggc gatcgcgtcg gccacaacga aagcctggat
    15721 gtcattggtg aacgcgtcga ccgcgctcat cagcacgccg acatgcgcgt agaccccgca
    15781 gacgatcagc tggtcgcggc cctcttcgcg cattctggcc agcaggttcg accggtggaa
    15841 cgcgctgtag cgccacttgg tgaagatcca gtcttcggca tccggcgcca ggggctcgac
    15901 gacctcacgg tcaacggggt cgacccgcat acccgggccc cagaagtcct tgagcagccc
    15961 gcgttgccgg gcggtcatgc cgccgggctg tgccgtgtac gccaccggga cgcggagttc
    16021 acggcaccgg tcgacgagca ccgcgatgtt gccgatgagt tgatgggcaa cgctttccgg
    16081 gaacggccgg aggaagtagc gctgcatgtc gtggatcagc aacaccgcac gggcggggtc
    16141 agtggtccag gtcgcggtgt tcgggggcag gtcggcgatc gcgggcagcg ggtacggcgc
    16201 gatcgcggga atacccacca tttcgttgtc tccctcaggg cgctgtgcgt tccagttgtt
    16261 cggcgaccgt gcgccagacc cgtgcgcact ccagcgccgc ttgggcgatc gttcccctgg
    16321 cgtgcggcgg cacgttgcgg accagcaacg cccatctgtc attgctcatc gcgtgcacgt
    16381 caagcaaccg caacaaggtc cggccggttt cggagaaccg cagcgtcggg tcggtccgca
    16441 ggtaccgcat gatcgtgacg cggtcaggca gcggcaacgg ctgaggtgca cgtgcctgcg
    16501 gctggcgccg ctcctccacc ttcttgatgt tgctgggttt ccggactgtc gggtcctcgc
    16561 cgcgttgcaa cctggcccgg acggcccgtg cggtctccgg ggagatgccc gcggccttgg
    16621 cgacctgccg cagcgacagg ttcgggttct gccgcatcag gttcatcgcc agcctgcgct
    16681 tctccaggct gttgatcggg cggacccggc cgtcctggcc gatccggctc tccggctgcg
    16741 gcaccttgcc gttgcggcgg acctcgccga tcgtcttcgc cgacaacccg gtcacgctcg
    16801 cgatcagccg atccgaccaa tgtggatggc tcatcacgat gctcttggct gcggctttgc
    16861 gttcggccaa cgacaacggc aggccgtgag cgacgttcgc gcgcaccgcg agcacgaacg
    16921 cgtcggcctc gtcaccgtcg aagaaccgga cggcgatgtc gtgctgatta cggagtttgg
    16981 ccgcccgcaa gcgatgcaca ccgtcgatca cccgcatcgt ctgccggtgc acgatgatcg
    17041 gcggcaactc gtccggcgcg tcggcaaggg cccggacgtg ttccaggttc tcacccgcga
    17101 tcctcggcga tccggcaacg cgcagtgccc tggtcgggac ccgcaccacc gggctcgcgc
    17161 ccgagttacc gtcgaggcag tcgaattctt cccgcggaag gctgacagca gcgaagttgg
    17221 tcacctcgac ctccagtact cacagcgaac ctggtgaccc gcagatgaga accagattcg
    17281 cagtgtgccg cagcgcacac cagtgagtga gccatcaggc caaaatgagg gattgtgggc
    17341 ccctatatga gtttttcacc cccgagttca cgagcgagaa ttctacggtg gtgtaaattt
    17401 tgtgttcgtc ggtggtccgg gcggcgcgat ttggtgtgga gcctctgcgc cgcaaagcag
    17461 gaccaacacc gcgggcagga cctgacggcc ctgcccgctg acaagcttat ttgcggcgcc
    17521 cctccacaca aaatcgcgcc ttcgctcggg gatgggctgg ttttcgctgt agggttttgg
    17581 ctggtcaggt taggtttgga caggttgcgc gttccggctt tttcaggatt tttccgtgcc
    17641 gcccttgccg aatcggaggc ctgcgaatac gcccgcgccg accacgacaa tggcgccgac
    17701 aatccatacc caaaccggga gtccgccgct gtcttcgttt tcctgggcgg ctggggctgg
    17761 ggtagcggtt gtcaccgcgg agccgttctg gccttgttgt gccgtcgatg tcgtggtggg
    17821 tggcgcagtg gtggtggtcg gggtcgtcgt agtgggtgcg gcgaccgctg ccgtgagggt
    17881 gaatggcacc tttccgctca ctggatcgcc gtctgccgaa atgacccggt aattgatggt
    17941 gtactggccg gccggtccaa ctggcgtgac cggggcggtg accacctcgt tcgcgaccgt
    18001 cacctggccg accgtccact gcgcgccggt gggtccggcg accgagatgg cgcctggttc
    18061 gacctggacc ggctcgctga aggtcagctg gatctgggtc ggtggcgtgg cgacggacgc
    18121 gttcttcgcc gggttgctgc tcttcagcga cgtgtgcgcg agcgcgggag cggcggtgac
    18181 cagcagcgct gtcgcgctga gcagcagtgc ggcggacatg cgcctgaaca tgtggtggcc
    18241 cttcacggtg aggtagtcgg ctggcggtgg actttagttc ccggaaactc ccaaaactca
    18301 gtggaactac cgattagacc gatcgggcca gcctcgtagg ctccggaggt gctcgtcgtt
    18361 cgggtgctgg gaccggtcga agtcgccgtc ggggacacca gggtggatct tggcggctcg
    18421 ttgccgcgca ggctgctggc cgctctggtc gccgctggcg ggcaggtggt cgccgacgat
    18481 cggctggccg agctggtctg gggtgcgaag ccaccggcga aggccgccgc gacacttcag
    18541 gtttacgtct cccggctgcg ccgggccttg gggccggagg gccggggcct gttggagcgc
    18601 gacggattcg gctaccggtt cgatgcggct cgtgccacgg tcgatgcgtc gcggttcatc
    18661 gagttgatcg aggccggccg tgggttgtcg ccgggcgagg cgatgcacgg gttgaccgag
    18721 gctttggagc tgtggcgtgg ccggccgtat gccgatctcg ccgagtccga cgacgtcgat
    18781 gccgctcgca gccggttgac cgagttgcgt gaggtggcgt tggaggaacg cgccgccgcc
    18841 cggctggcca ccggtgatgc cacaggcgca gtgcctgacc tcgaggaact cgtgcgagcg
    18901 gcgcctttgc gggagcgacg ctgggcgttg ttggttctcg cgctgtaccg gtgtggacgg
    18961 cagggggacg cgttggccgc ggtacggcgg gctcgtgccg tgctcgctga ggaattgggt
    19021 gttgacctgg gtgttgagct gcaggatctg gaacggcagg tgctcgctca ggatccgtcg
    19081 ctgcggaagc ggccgagtgg gcggccgttg acgtcctttc ttgggcgtga caccgagctg
    19141 gacaccatcg ccagcttgtt cggggcacaa cggctggtca gcctggttgg tccggccggg
    19201 gtaggaaaga cccggcttgc ggtcgagtac gcggatgacc cgtggttcgc acggctggct
    19261 gatgtgcgtc accccggcga gttgcccagt gtggtggccg atgcgatcgg cctggtcgcg
    19321 gtgcgggacg acccggtctc ggcagtcatc cgggccatcg gtgaccgctc cggcctgctg
    19381 gttctggaca actgcgagca cgtcatcgag gctgtcgccg acttggtcgt cgcgttgctc
    19441 ccccattgtc ctgggttgcg cgtgctggcg acgagccgtg aaccgctcgg aatcgatggt
    19501 gaggtcaccg tcgcggtcca gccgctgccg ccgaagtccg ccgaggctct gctggtcgat
    19561 cgggtgcagg cggttcggcc gggctggcag cccaccattg acgaacgggc gcaggccagc
    19621 cggatcagcg cggcgctgga cgggctgccg ctggcgatcg agctcgccgc ggcgcgcgcg
    19681 agaatgttcg ggctcgggga aatcgccgaa cggctcaccg accggttcgc agtgctcggt
    19741 tcggtgccgc ggggatcgtt gacggcgcac gcgacactcg aggctgccat cgggtggagc
    19801 gtggacctgc tgtccgattc ggaccgcgcg ttgctgcttc gattgtggcc tttcgaaggc
    19861 gggttcacgt tggaagccgc ggacgccgtc cgccctgcgg cgcagaccga gacgacactg
    19921 gagcttctgt cctcattggt cactcggtcc gttgttgtcg cggataccag tgagatgccg
    19981 acgcgatacc tgatgctgga aagtgttcgt gcctactgcc agtcgatcga cccggatccc
    20041 gcgtcggccc agcacgcgca tgcccaatgg gtcacgggtt tgggtgagcg ttgggtggtc
    20101 gcggtacgca ccaggcgcgg cggccaattc atgtcggcgg tcagtcgcga gctgccgaac
    20161 atccgcgcgg ggttggcgta tctgcgtgaa cactccccgg acgtcgcgtt gcacactttc
    20221 ggtttgctcg ctttgttgtt cactcgccac gtccacaaga aggaagccat cacgttggcg
    20281 tgggagctgt tgcgggcagc tccggacgct cccgtgttcg accgggtgcg cgccatggtc
    20341 acccagacgg cgttggtcgc catcggcggc gaccgtgaca gcgcgataca gatcatcagc
    20401 gaggcgttcc ggctggccaa gaagatgccc gtcgatgatc cggtcgacgt cgccgagtt
//
