LOCUS       NZ_FWXV01000003        11806 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000003
VERSION     NZ_FWXV01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 403291
            Orig. end                         :: 415097
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11806
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11806
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11806
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6806](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6806)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(520..1110)
                     /gene="nthA"
                     /locus_tag="B9C43_RS20865"
                     /old_locus_tag="SAMN05661093_04253"
     CDS             complement(520..1110)
                     /EC_number="4.2.1.84"
                     /GO_function="GO:0018822 - nitrile hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046914 - transition metal ion binding
                     [Evidence IEA]"
                     /GO_process="GO:0050898 - nitrile metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nthA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018333883.1"
                     /locus_tag="B9C43_RS20865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04253"
                     /product="nitrile hydratase subunit alpha"
                     /protein_id="WP_033392305.1"
                     /transl_table=11
                     /translation="MSGDHSDAPIAARVRRMESLLEERGLVIPGALDETLAAFLNRASP
                     ANGARIVARAWVDPEFRDRLLADAPAAIAELDFSMSGGLHVQDLQAVANTEREHNVVVC
                     TLCSCYPLALLGPSPTWYKSESYRSRVVRNPREVLREFGFELRPEVEIKVWDANAETRY
                     IVIPARPAGTENLTEQQLAELVTRNGLIGTAPV"
     misc_feature    complement(769..771)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1107..1370)
                     /locus_tag="B9C43_RS20870"
                     /old_locus_tag="SAMN05661093_04254"
     CDS             complement(1107..1370)
                     /EC_number="4.2.1.84"
                     /GO_function="GO:0018822 - nitrile hydratase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014289.5"
                     /locus_tag="B9C43_RS20870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04254"
                     /product="SH3-like domain-containing protein"
                     /protein_id="WP_084428577.1"
                     /transl_table=11
                     /translation="MTFTTGDRVRAKSVDPPHHTRLPSYIRGAVGTIVGNQGAHPVPDD
                     VVRGFSAPAETVYAVRFTAGELFGTGDHTVTVSLWQRYMERL"
     gene            complement(1351..1644)
                     /locus_tag="B9C43_RS20875"
                     /old_locus_tag="SAMN05661093_04255"
     CDS             complement(1351..1644)
                     /EC_number="4.2.1.84"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045268.2"
                     /locus_tag="B9C43_RS20875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04255"
                     /product="SH3-like domain-containing protein"
                     /protein_id="WP_084428578.1"
                     /transl_table=11
                     /translation="MSRINDVGGVQGFGMIEADQDEPPFHADWEAHVFALNGALIRHGI
                     YQLDEFRDAIERLSPSQYLAASYYERWFLAIRTLLIEKGVFTEEELDDVHDR"
     misc_feature    complement(1631..1644)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.91"
                     /tool="antismash"
     gene            1712..1897
                     /locus_tag="B9C43_RS20880"
                     /old_locus_tag="SAMN05661093_04256"
     CDS             1712..1897
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS20880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_04256"
                     /product="hypothetical protein"
                     /protein_id="WP_033392304.1"
                     /transl_table=11
                     /translation="MQTRSRLKEALTLTAVLCFIYTVAIFFTALGGKVDYVYAWITGPV
                     AMVIGLALIFRCRPGG"
     misc_feature    complement(1911..1923)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            1925..2677
                     /locus_tag="B9C43_RS20885"
                     /old_locus_tag="SAMN05661093_04257"
     CDS             1925..2677
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985615.1"
                     /locus_tag="B9C43_RS20885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04257"
                     /product="potassium channel family protein"
                     /protein_id="WP_084428579.1"
                     /transl_table=11
                     /translation="MTEQRLSNWERRTEWPLSALAVAFLVAYAWQVLHVSAPAGVHLGL
                     EITLWVIWLVFAADYVTRLILAERKLRFIWRHLFDLVAVALPMVRQLRVLRIVTVLRVL
                     NRRASTAFRGRVAIYVAMVTVLVSFAAALAVLDAERANPDAGIDSFPKALWWTLTTIST
                     VGYGDVYPTTWEGRLVAAALMIGGIALLGVITGMIASWLLERIQQSEATVQQETDELHV
                     ELVTLREEVRRLREELANQGSSPPRAMS"
     gene            complement(2644..3801)
                     /locus_tag="B9C43_RS20890"
                     /old_locus_tag="SAMN05661093_04258"
     CDS             complement(2644..3801)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692788.1"
                     /locus_tag="B9C43_RS20890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04258"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_084428580.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.8e-35, bitscore:
                     116.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.8e-25, bitscore:
                     83.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.9e-46, bitscore:
                     153.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLSDDEQFIVRTVRQFVDKDVKPVVRELEHADTYPEALIERMK
                     ELGIFGLAVPEEYGGTPVSTPCYVLITEELARGWMSLAGAMGGHTVVCKLLLKFGTPEQ
                     KQHYLPRMATGEVRATMALTEPGGGSDLQAMRTVARKSADGYVVNGSKTWITNSRRSRL
                     IALLCKTDPDARPAHQGISILLAEHGPGLTVSRDLPKLGYKGVESCELSFEDYRAPLAA
                     VLGGVEGHGFAQMMSGLETGRLQVAARALGVGRAALEDSLAYAQSRESFGKPIWQHQSI
                     GNYLADMATSLSAARQLTLHAAREADAGRRVDMEAGMAKLFASETAMQIALTAVRIHGG
                     YGYSTEFDVERYFRDAPLMIVGEGTNEIQRNVIVRQLIARGGLEP"
     gene            complement(3798..4964)
                     /locus_tag="B9C43_RS20895"
                     /old_locus_tag="SAMN05661093_04259"
     CDS             complement(3798..4964)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943542.1"
                     /locus_tag="B9C43_RS20895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04259"
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="WP_084428581.1"
                     /transl_table=11
                     /translation="MTDLPLAGVTVVSLEQAVAAPFATRQLADLGARVIKVERPGGGDF
                     ARRYDTTVHGQSSYFVWLNRSKESLTLDLKSGRGREILHRLLAGADVFVQNLAPGAAAR
                     LGLDKDSLTYEKLITCTISGYGEPWADRKAYDLLVQCQTGLVSLTGTPEGAARVGVSVA
                     DIAAGMYAYSGILTALYTRAMTGKARSVDVTLFDALAEWMGQPAYYTRYSGTQPPRVGT
                     QHATISPYGAYTAADGKDVLFSIQNEREWISLCEQFLDRPELVDDPRYATGSARVEHRD
                     EVNAIVAQRFNEIDSTEVMALLDKAGIANAGVNSVQEFLDHPVLAGRWQDVGIPGGSMT
                     ALPPPAKLDGIAARMDPVPDVGEHTDQILGTLGYSASDIQQLRAEEIV"
     gene            complement(5001..6806)
                     /locus_tag="B9C43_RS20900"
                     /old_locus_tag="SAMN05661093_04260"
     CDS             complement(5001..6806)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640481.1"
                     /locus_tag="B9C43_RS20900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04260"
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_084428582.1"
                     /sec_met_domain="TIGR03975 (E-value: 1e-188, bitscore:
                     624.3, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.5e-16, bitscore: 55.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTALVSMPFMHVDRPSIQLGLLRAIGEANGFPVRTVHANLDFAA
                     RVGTEYYQALADMRGRMIGDWLFSVEAFGADAPDQDALLADEFAAELSYLADDGRVRDR
                     LTRTRDDDVPAFLDDLVGGFPWHEVQVVGFSCTFQQNTASFALARRLKERFPGIVTVFG
                     GANFDGEMGLELVRSVDCVDYAVIGEGDTAFPRLLKALADGTDPLAVPGVASRHGATPA
                     EPPLEVLDETPVPVYDEYFQRAEKAGLLPEVVWLPFESARGCWWGAKHHCTFCGLNGTT
                     MKFRAKSPERVLAELATQARRYGVFRFEAVDNIMDPRYLKEVFPAVVDSGSDYEFFYEV
                     KANLTRAQLKLLAAGGVTHLQPGLESLSSHVLRLMDKGVRAAQNVNLLRWARYYGIDVG
                     WNILWGFPGETADDYAKQAAVVPNLVHLQPPVGAARVWLERFSPMYTRFTMRHRAPERS
                     YQYVYPKTVDLDKVAYFFEYEMDDALPAETYADLASEVAMWSDRWEAKQRPMLTYWSSP
                     GYLRIYDGRHEGREGTYTFRDTLARIYLACSDRPTTASAVRNKLGLDVPVRAIEDAFAQ
                     FEERGLMFLDESLAVSLALPATRYR"
     misc_feature    complement(6765..6779)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(6809..7081)
                     /locus_tag="B9C43_RS20905"
                     /old_locus_tag="SAMN05661093_04261"
     CDS             complement(6809..7081)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS20905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_04261"
                     /product="hypothetical protein"
                     /protein_id="WP_084428583.1"
                     /transl_table=11
                     /translation="MDDATSAQDFAALLPEIDKFARELPDKDRLLFDKMLTGAAETIMN
                     SFQSYATEFGEAFRGGKTQLTISYESGGYDDPLVCGKYCTRYVKP"
     gene            complement(7115..9811)
                     /locus_tag="B9C43_RS20910"
                     /old_locus_tag="SAMN05661093_04262"
     CDS             complement(7115..9811)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020647162.1"
                     /locus_tag="B9C43_RS20910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04262"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_084428584.1"
                     /transl_table=11
                     /translation="MEFRLFGEVQLRAGGKLADVGTPRQQAVLAALLVDAGKPVPIETL
                     IDRVWNETPPAEVRNVLYSHLSRIRRLLKDTARLERRPAGYVLDVPPGSVDMHRFWQLV
                     EQSKDLSDTDKAATLAEALALWRGPPLAGVQGEWVDQVRDRWSRRRLDAIVQWGDVELR
                     LGRPAQVIDVFRDLAAEYPLAEQFEHVLMRALHAAGRDAEALDRYTVIRQRLADELGTG
                     PGPELQALHSSLLRGELPKPRRANSAAPAQLPPDVYGFAGREEQLGQLGKLERARIVVV
                     SGTAGVGKTSLVVHWAHQVRADFPDGQLYLNLRGFDPTGTPVAPAEAVRGFLDAFYVPR
                     ERVPAGFEAQVGLYRSLLADRRVLIVLDNARDAEQVRPLLPGSSQCLVLVTSRDQLAGL
                     VAEGAHPLMLDLLDVAEARTLLVRRIGAERVAAESEAVDEIIRLCARLPLALAVVAARA
                     ATHPKFSLAALADELREGLDELSGADPATDPRAVFSWSYLQLNETSARLFRLLGLHPGP
                     DFGIRAAASMAGLPVAQVRPPLAELAGAHLVAEESPGRYEFHDLLRAYAAELAQGDSDR
                     HAARRRMLGYYVHNGNRADRLLDPFRENPPGFPELPGHVVVESISDKARALAWFNAEYR
                     VMLAVINQTHGFDEEVWSLAWTLRRYFTRRGLRHEQLSALLPALEAARRMGDPAKEAYA
                     QCFIGSSHVLFGRVDEGAELLGVALGLYRKAGDRLGEGLVLQCFCWMLERENRHAEALK
                     YAQHCLDVFRAAGHKPGEGRALNAVGFLHALLGAHVDALNYCQKAIDLQLKLGDSVGAA
                     QTWDSLGLAYSRLGDHERAIVCHQSSVDVNRELGNRHSEAIALTSLGDAYKNAGDIESA
                     HIAWQRAVEKFEQIGIPEADEVRAKLG"
     misc_feature    complement(8372..8374)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9865..9880)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.42"
                     /tool="antismash"
     gene            9914..10495
                     /locus_tag="B9C43_RS20915"
                     /old_locus_tag="SAMN05661093_04263"
     CDS             9914..10495
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="B9C43_RS20915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04263"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_033392308.1"
                     /transl_table=11
                     /translation="MVLTALVHGATRGQAWAWATLVQRYRPLVSAICRNLGITGVDADD
                     VAGTVWLRLVANMTTIRDPEALPGWIVTTTRRECLQMLRDRSRQVAQETEDMADVSCPG
                     PDNRLLVDERRDALREAIDGLSDRDQQLLSMLFADPPIPYAEISARLGMPIGAIGPTRQ
                     RCLARVRRSPGIAALLVNECHANRRRAEAV"
     misc_feature    complement(10750..10763)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.6"
                     /tool="antismash"
     misc_feature    11745..11760
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.84"
                     /tool="antismash"
ORIGIN
        1 ggccgcgatc gccgccaagg atgccgcgtc ggccactgcc gttcagcagg tgctgcgttc
       61 gacgaaggat gacgcgccga tgatcgacgt gttgtcggac cgccacgacg gtttgctgca
      121 gggagacgcc gaacttctcc gtggcgcggc acgccgattc gagtcgatgg gcgcaccact
      181 gcttgccgca cagaccttgt tggaagccgc ggagctggag cccgaccgcg acaccgttct
      241 ccgctgtctg aagaagctgc aacacgtcaa accatggttc gaccgtgccc gcaggctggc
      301 cagggctcag cggatcgaac gcggcgacgg cgtcctcacc aggcgggaag ccgaaatcgt
      361 ccggcttgtc ggcgctggac tgtccaatgc ggacatcgcg gcccggctct ttctcagcgc
      421 ccgcacggtc gagacccacc tgcgtaacag ctaccgcaag ctggacatca cctcacggct
      481 gcggctcgcc caatgggctc tgcaacacga cgacgagctc taaacgggcg ctgtcccgat
      541 cagaccgttg cgggtgacca attcggccag ctgttgttcg gtgaggttct cggtgcccgc
      601 cggccgggcg ggaatgacga tgtaccgggt ttccgcgttg gcgtcccaca ccttgatctc
      661 gacctcgggc cgcagttcga agccgaattc ccgcaacacc tcgcggggat ttcggaccac
      721 cctcgaccgg tagctctcgc tcttgtacca agtgggtgac gggcccagta aggcgagcgg
      781 gtagcaagag cacagcgtgc acacgaccac gttgtgctca cgctcggtat tggccaccgc
      841 ctgcaggtcc tgcacgtgca atccgccgct catcgagaag tcgagttcgg cgatcgcggc
      901 gggggcgtcg gcgagcagcc ggtcccggaa ttccggatcc acccacgccc tggccacgat
      961 ccgggcgcca ttggctggtg acgcacggtt gagaaaggcc gccagcgtct cgtcgagagc
     1021 acccggaatc accaggccgc gctcttcgag caggctttcc atccgccgga cccgtgccgc
     1081 gatcggcgcg tcggaatgat caccactcac agccgctcca tgtacctctg ccacaggctc
     1141 accgtcacgg tgtgatcgcc tgttccgaac aattcaccgg cggtgaaccg gactgcgtaa
     1201 accgtctccg ccggcgcgga aaacccccgt acgacgtcgt cgggaaccgg atgagcgccc
     1261 tgatttccca cgatcgtgcc gaccgcgccc cggatgtagg acggcaggcg ggtgtggtgc
     1321 ggcggatcga cgctcttggc ccggacccgg tcaccggtcg tgaacgtcat ccagctcctc
     1381 ctcggtgaac acacccttct cgatcaggag tgtgcgaatc gccaaaaacc accgctcgta
     1441 gtaggacgcc gccaggtact ggctgggtga caggcgttcg atcgcatcgc ggaactcgtc
     1501 gagctgatag atcccgtgcc ggatcagcgc accgttgagg gcgaagacgt gtgcctccca
     1561 gtccgcatga aagggcggct cgtcctggtc ggcttcgatc atgccgaacc cctgcacacc
     1621 gcccacatcg ttgatccggc tcatgatccg atgttaactc tgggaacaag acctcacgcc
     1681 taattcgcag tcactgggtt accctcagtt catgcagacc aggtcacggc tgaaagaggc
     1741 gttgacgctc accgccgtgc tctgcttcat ctacacggtc gcgatcttct tcaccgcgct
     1801 cggcggcaaa gtcgactacg tgtacgcctg gatcaccggg ccggtcgcga tggtcatcgg
     1861 gcttgccctg attttccgct gccggccagg cggctgaggc cccgatcgcg gttacagtgt
     1921 cgcggtgacc gagcagcgac tgtccaattg ggaacggcga accgagtggc cgctgagcgc
     1981 actcgccgtg gcgttccttg tcgcatatgc ctggcaggta ctgcatgtca gtgcgccggc
     2041 aggcgtgcat ctcggactgg agatcacgct ctgggtgatc tggttggtat tcgctgccga
     2101 ctacgtgacc cggttgatcc tcgccgagcg gaaactgcgg ttcatctggc gtcacctgtt
     2161 cgatttggtc gcggtggcgc tgccgatggt ccggcaattg cgggtactgc ggattgtcac
     2221 ggttttgcgg gtgctcaacc gcagggcgtc gacggctttt cgtggccggg tggcgattta
     2281 tgtcgccatg gtgaccgtac tggtcagttt cgccgcggcg ctcgccgtgc tggacgccga
     2341 acgggccaat ccggacgccg ggatcgactc gttcccgaaa gccttgtggt ggacgctgac
     2401 cacgatctcg acggtcgggt acggcgatgt ctatccgacc acgtgggaag gcaggctggt
     2461 cgcggccgcc ctgatgatcg gcggaatcgc gttgctcggt gtgatcaccg gaatgatcgc
     2521 gtcctggctg ctggaacgaa ttcagcaaag cgaggcgaca gtgcagcagg aaaccgacga
     2581 actgcacgtc gaactggtca cgctgcgcga ggaggtccgc cggttgcgcg aggagctggc
     2641 caatcagggc tccagtccac cgcgggcgat gagctgacgc acgatcacgt tgcgttggat
     2701 ctcgttggtg ccctcgccca cgatcatcag tggcgcgtcc cggaaatacc gctccacgtc
     2761 gaattcggtg gagtacccgt acccgccgtg aatgcggacc gcggtcaacg cgatctgcat
     2821 cgcggtctcc gacgcgaaca gcttcgccat tccggcttcc atgtccaccc ggcggcccgc
     2881 gtcggcctcc cgtgccgcgt gcagggtcag ttgacgcgcc gcggacaacg acgtggccat
     2941 gtcggccagg tagttgccga tggactggtg ctgccagatc ggtttgccga acgactcccg
     3001 gctttgcgcg tacgccagtg aatcctccag cgcggcccgg ccgaccccga gcgcccgcgc
     3061 ggccacctgc agcctgccgg tctccagccc ggacatcatc tgggcgaacc catggccttc
     3121 cacaccaccg agaacggcgg ccaacggcgc ccggtagtcc tcaaaggaca gttcacagct
     3181 ctcgacgccc ttgtagccga gcttcggcag atcgcgggac acggtcaggc caggaccgtg
     3241 ttcggccagc aggatcgaga tgccttggtg tgccggtcgc gcgtcgggat ctgtcttgca
     3301 cagcaaggcg atgagccttg agcggcggga gttcgtgatc cacgtcttcg atccgttgac
     3361 gacgtagccg tcagcggatt tgcgggccac cgtgcgcatg gcttgcagat ctgacccgcc
     3421 gccgggttcg gtcagcgcca tcgtcgcacg gacctcgccc gtggccatcc gcggcaaata
     3481 gtgctgtttc tgctcaggtg tcccgaattt gagcaggagc ttgcagacga ccgtgtgccc
     3541 gcccatcgcg cctgccaggc tcatccagcc acgcgccagc tcctcggtga tcagcacgta
     3601 gcacggcgtc gagaccggag tgccgccgta ctcctcgggg acggccaggc cgaagatgcc
     3661 cagttccttc atccgctcga tcaacgcctc ggggtaggtg tcggcgtgtt cgagctcgcg
     3721 gacgaccggt ttgacgtctt tgtcgacgaa ctgtctgaca gtccggacaa tgaactgttc
     3781 gtcgtcggac agcgtggtca tacgatctcc tcggcccgca actgctggat gtcgctcgcg
     3841 ctgtagccca gcgtgccaag gatctggtcg gtgtgctcgc cgacatccgg caccggatcc
     3901 attcgtgcgg cgatcccgtc gagcttcgcg ggcggcggca acgccgtcat cgacccgccg
     3961 gggatgccga catcctgcca gcgcccggcg agcaccgggt ggtcaaggaa ctcctgtacc
     4021 gaattgaccc cggcgttcgc gatgcccgct ttgtccagca gggccatgac ctcggtgctg
     4081 tcgatctcat tgaatcgttg cgcgacaatg gcgttgactt cgtcgcggtg ctcgacccgc
     4141 gccgacccgg tggcgtaccg cgggtcgtcg acaagctcgg gccggtcaag gaactgctcg
     4201 cacaacgaga tccattcgcg ctcgttctgg atggagaaca acacgtcctt gccgtcggcc
     4261 gcagtgtagg cgccgtacgg ggaaatagtg gcgtgttgcg taccgactcg aggtggttgt
     4321 gttccgctgt aacgggtgta gtacgcgggc tgccccatcc actcggccag agcgtcgaac
     4381 agcgtcacgt ccaccgaacg ggcttttcct gtcatggcac gggtgtagag cgcggtgagg
     4441 attcccgagt acgcgtacat cccggccgcg atgtccgcaa cggacactcc gacgcgtgcg
     4501 gctccctcag gcgttcccgt caatgacacg agcccggttt ggcactgcac aagaaggtcg
     4561 tacgctttgc gatccgccca tggttcgccg tacccggaaa tcgtgcacgt gatgagcttc
     4621 tcgtacgtca ggctgtcctt gtccaagccg agcctcgccg cggccccagg ggcgaggttc
     4681 tgtacgaaga cgtccgcgcc tgccagcagc cggtgcagga tttccctgcc gcgcccggat
     4741 ttcaggtcga gcgtgagcga ttccttcgac cggttcagcc atacgaagta gctggattgg
     4801 ccgtgcactg tggtgtcgta gcggcgggcg aaatcgccgc cgcccggacg ttccactttg
     4861 atcacccggg caccgagatc ggccagttgc cgggtggcga acggcgcggc cacagcctgc
     4921 tcaaggctga cgacggtgac accggcgagc ggaagatcag tcactccgct actttaactg
     4981 ccccccagtc atcgatacag tcatcgatac cgcgttgcag gcagggcgag tgaaacggcc
     5041 agcgactcgt cgaggaacat caggccgcgc tcctcgaact gggcgaacgc gtcctcgatc
     5101 gcccgcaccg gcacgtcgag accgagcttg ttcctgactg ccgacgcggt cgtcggccgg
     5161 tcactgcacg ccaggtagat gcgcgcgagt gtgtcgcgga atgtgtacgt tccctcgcgg
     5221 ccttcgtgcc tgccgtcgta gatccgcagg tatcccggcg acgaccagta ggtcagcatc
     5281 ggccgctgtt tcgcttccca gcgatcgctc cacatggcca cttcactggc caggtcggca
     5341 taggtctcgg cgggcagcgc gtcatccatt tcgtattcga agaagtacgc gaccttatcg
     5401 aggtcgactg tcttcgggta cacgtactgg tagctgcgtt ccggtgcccg gtgccgcatc
     5461 gtgaaccggg tgtacatcgg gctgaaccgc tccaaccaga cacgtgcggc accgacgggc
     5521 ggctgcaggt gaacgaggtt cgggacaacg gccgcttgct tggcgtagtc atcggcggtc
     5581 tcgccgggaa atccccacag gatgttccag ccgacatcga tcccgtaata ccgcgcccag
     5641 cgcaggaggt tgacgttctg cgcggccctg acgcccttgt ccatcaagcg gagaacgtgg
     5701 gagctcaacg attccaggcc tggctgcaag tgcgtgacac cacccgcggc gaggagcttg
     5761 agctgggcgc gggtcaggtt cgctttgacc tcgtagaaga actcgtagtc cgaaccgctg
     5821 tcgacgaccg ccgggaagac ttccttgaga tagcgcgggt ccatgatgtt gtcgacggct
     5881 tcgaaccgga acacgccgta tcgccgtgcc tgcgtggcca gttcggccag cacccgctcc
     5941 ggcgacttgg cgcggaactt catcgtcgtg ccgttgagac cgcagaacgt gcaatggtgt
     6001 ttggctcccc accagcagcc acgggccgac tcgaacggaa gccatacgac ctcgggcagc
     6061 agaccggctt tttcggctcg ctggaagtac tcgtcgtaca ccggcacggg tgtctcgtcg
     6121 agtacttcaa ggggcggctc cgcgggagtc gcgccgtgtc gacttgcgac acctggcact
     6181 gccaatggat cagtaccgtc ggccaatgcc ttgagcagcc ggggaaacgc ggtgtcgcct
     6241 tcgccgatca cggcgtagtc gacgcagtcg accgaccgca cgagctccag gcccatctca
     6301 ccgtcgaaat tggccccgcc gaagacggtg acaatgcccg gaaagcgctc cttcaaccgt
     6361 cgtgccaagg cgaacgacgc ggtgttctgc tggaacgtac agctgaaccc gacgacttgg
     6421 acttcgtgcc agggaaatcc cccgaccagg tcgtcgagga acgcaggcac atcatcatcg
     6481 cgagtccgcg tcagccggtc gcggacgcgc ccatcatccg ccaaatagga cagttcggcc
     6541 gcgaattcgt cggcgagcag ggcatcttga tcaggcgcgt ccgcgccgaa cgcctcgacc
     6601 gagaacaacc agtcgccgat catccggcca cgcatgtccg cgagcgcctg gtagtactcg
     6661 gtcccgacgc gtgcggcgaa atccaggttg gcgtgcaccg tacgcaccgg gaagccgttc
     6721 gcctcgccga tcgcccgcag cagtcccagt tggatggacg ggcgatcgac gtgcatgaac
     6781 ggcatcgaga cgagagccgt gtgcatgact acggcttgac gtatctcgtg cagtacttgc
     6841 cgcagacgag aggatcgtcg tacccgccgc tctcatagct gatggtcagc tgcgtcttcc
     6901 cgccgcggaa ggcctcaccg aactcggtgg cgtaggactg gaagctgttc atgatcgtct
     6961 cggccgcgcc ggtgagcatc ttgtcgaaca gcaaccggtc cttgtccggc agttctcgag
     7021 cgaacttgtc gatctccggc agcagggcgg cgaaatcctg tgcgctggtg gcgtcgtcca
     7081 tctctcccct tcgtggtggt tatcccagtg gtggtcatcc cagtttggct ctgacctcgt
     7141 cggcttccgg aattccgatc tgctcgaact tctcgaccgc gcgttgccag gcgatgtggg
     7201 ccgactcgat gtcgcccgcg ttcttgtacg cgtctcccag cgaggtgagg gcgatggcct
     7261 cggagtgccg gttgcccagc tcacggttga cgtcgaccga cgactggtgg cagacgatcg
     7321 cgcgctcgtg atcgccgagc ctgctgtagg caagcccgag gctgtcccac gtctgtgccg
     7381 cgcccacgct gtcgccgagt ttcagttgca ggtcaatggc tttctggcag tagttgagcg
     7441 cgtcgacgtg cgcgccgagc agggcgtgca ggaatccgac ggcgttgagt gcccggcctt
     7501 ctcccggctt gtgacccgcc gcccggaaca cgtcgaggca gtgctgggcg tacttgagcg
     7561 cttcggcgtg ccggttctcg cgttccagca tccagcagaa gcattgcagc acaaggcctt
     7621 caccgagccg atcgcccgct ttgcggtaga ggccgagcgc gacacccagc agttcggcgc
     7681 cttcgtccac ccgtccgaaa aggacgtggg acgagccgat gaagcactgc gcgtacgcct
     7741 ctttggccgg atcgcccatc ctccgtgccg cttcaagcgc gggcaggagc gcgctgagtt
     7801 gctcgtgccg cagtccccgg cgggtgaagt accggcgcaa cgtccatgcc agcgaccaga
     7861 cttcctcgtc gaagccgtgt gtctggttga tgacggccaa catcacgcgg tattcggcgt
     7921 tgaaccacgc caatgcccgc gccttgtccg atatggactc cacgacgaca tggccgggaa
     7981 gctcagggaa gccgggcggg ttctcccgga acgggtcgag caggcggtcc gcccgatttc
     8041 cattgtggac gtaatagccg agcatgcgcc gccgggcggc atgccggtcg ctgtcccctt
     8101 gggcgagttc ggcggcgtag gccctcagca ggtcgtggaa ctcatagcgg ccagggcttt
     8161 cctcggcgac caggtgcgct ccggccagct cggccaacgg tgggcgaacc tgcgcgaccg
     8221 gcagcccggc catgctggcc gccgcacgaa tgccgaagtc aggcccggga tgcaggccca
     8281 acaaccggaa cagccgcgcg ctggtctcgt tcagctgaag gtaggaccac gagaacacgg
     8341 cgcggggatc ggtcgccgga tcggcgccgg ataactcgtc caagccttcg cgcagctcgt
     8401 cggccagcgc ggcgaggctg aacttgggat gcgtcgcagc ccgcgccgca accacagcca
     8461 acgccaacgg aagccgagcg cagagccgga tgatctcgtc caccgcttcg gactcggccg
     8521 cgacgcgttc cgcgccgatc ctccgcacca gcagagtgcg tgcctcggcg acgtcaagca
     8581 ggtcgagcat cagcggatgc gcgccctcgg ccaccagccc ggcaagctga tcccggctgg
     8641 tgaccagcac gagacactgc gacgaaccag gcagcagcgg gcgaacctgc tcggcgtcgc
     8701 gggcgttgtc cagcacgatc agcacgcgac ggtcggccag cagactgcgg tagagcccga
     8761 cctgggcctc gaaccccgcc ggaacccgtt cgcgcggcac gtagaaagca tcaaggaacc
     8821 cgcgcacggc ctcagcgggc gcgaccggcg tccccgttgg atcgaacccg cgcaggttca
     8881 ggtacagctg gccgtcgggg aagtccgcgc gcacctggtg cgcccagtgc acgaccaggg
     8941 acgtcttgcc gacgcccgcg gtccccgaga ccacgacgat ccgggcccgc tcgagcttgc
     9001 ccaactgtcc tagttgctct tcccggccag cgaacccgta gacgtcaggc ggaagttgcg
     9061 cgggcgcggc gctgttcgcc cgccgcggct tcggcaactc gcccctgagc agcgaactgt
     9121 gcagggcctg cagttccggt ccagggccgg tgcccagttc gtccgcgagc cgttgccgga
     9181 taacggtgta acgatcaagc gcctccgcgt cccggcccgc cgcgtgcaac gctcgcatga
     9241 ggacgtgctc gaactgctcg gccaacgggt actcggcagc cagatcgcgg aacacgtcga
     9301 tgacctgtgc gggccgcccc agccgcagct ccacgtcacc ccattggacg atcgcatcga
     9361 gtcttcgccg cgaccagcga tcccggacct gatcgaccca ttcgccctgg acgcccgcga
     9421 ggggcgggcc ccgccacagc gccaacgcct cagcgagcgt cgcggccttg tcggtgtcgc
     9481 tgaggtcctt gctctgctcg accagctgcc agaaccggtg catgtccact gagccgggtg
     9541 ggacgtcgag gacgtacccg gcgggccggc gctccagtct tgccgtgtcc ttgagcagcc
     9601 tccggatccg gctgaggtgc gagtagagga cgttgcggac ctcggccggt ggcgtctcgt
     9661 tccagacgcg gtcgatcagc gtctcgatcg ggaccggttt tccggcgtcc acgagcaggg
     9721 cggccagcac ggcttgctga cgtggcgttc ccacgtcggc gagcttgcct cccgccctca
     9781 gctgcacctc cccgaacagc cgaaactcca tggatctcga tgcttgtcgg tccgcaaggt
     9841 tgctgcaagg tccgcgagca gggcgtggcg aaatcgtgaa gccggtcggt tgctcaccga
     9901 gcgggggaag acgatggttc tgacggctct tgtgcacggc gcgacgcgcg gacaagcctg
     9961 ggcgtgggcg acgcttgtcc agcgatatcg gccgctggtg tcggcgatct gccgcaacct
    10021 cgggatcacg ggcgtggacg ccgacgacgt ggccgggaca gtgtggcttc gcctggtggc
    10081 gaacatgacg acgattcgtg acccggaggc cctgccgggc tggatcgtga cgacgacgcg
    10141 gcgggagtgc ttgcagatgc tgcgggaccg gagtcgccag gtggcccagg agaccgaaga
    10201 catggcggac gtgtcgtgcc cggggccgga caaccggttg ctggtggacg aacgacgcga
    10261 cgcgctgcgc gaggctattg acggactgtc cgatagggat cagcagctgc tgtcgatgtt
    10321 gttcgcggat ccgcctattc cgtacgccga gatcagtgcg cggctgggga tgcctattgg
    10381 agcgattggg ccgaccaggc agcggtgtct tgcacgggta cgccggagtc cgggtatcgc
    10441 cgcgctgctg gtcaacgaat gtcacgctaa taggaggcgg gccgaagcgg tttgatacag
    10501 ggtttcggtc cggctgaggt tcggctcagg gttccgggta cttgggtgcg gccggctggg
    10561 gcggcgctcg tcctgtttca tctgccccgg atgtccgaat cggggactag gccgtgtggc
    10621 ctatggttgg ggcgtgcgct ctcgtcggtt gatcgccggt cgttatcggc tggaagagca
    10681 gctcggctcc ggtggaatgg gtgtcgtgtg gcgggccacc gatgaagagc ttggccgcgt
    10741 tgtcgccgtc aaacgggcgc ttccggtcgc cggtgcacag gccaagctgc tcaaacggga
    10801 agccaaggcc gccgcgcggg tgaatcaccc gaatgtggtg acgttgtacg acgtcgtcac
    10861 ttctggcgat gaagtgtggc ttgtcatgga atacctgcct gccagcacct tggccggaca
    10921 gggtgtgttg cctgcgggcc gagtcgcgca gatcggtgtg cagctcgccg atgcgttgac
    10981 cgcgattcat gccgccggtg tgctgcatcg ggatgtcaag ccgagcaatg tgttgatgac
    11041 caatgacggg cggccgaagc tcactgattt cggggtctcc cgcagcgtcc acaatgacat
    11101 cacggtgagc aggaccggcg gtcttgatgg gacgcccgga tatctcgcac ccgaagtcgc
    11161 ccgcggcgag gacgctacct ccgcatcgga cgttttctcg ctcggtgcca cgttgttcgc
    11221 ggcggtcgaa ggtgtgtcgc cggtcggtaa agccgacaac ccacaggtat tggtgtggcg
    11281 tgctgctcgt ggggacatcg cggaatcgca cgggccgctc cggcaggtgt tgtccgcttt
    11341 gctcaagcct gatccgcgta aacggccgac tgccgcgcag gccaagcaga tgcttgaggc
    11401 cgtcgccaac ggcattcgcc agcggccgcc gatcctggca agggcggcga tcctgctcgt
    11461 tctcgtggcc acttggggtt tgctgagcta tccgagtgag tctgcctccg ccgcttctcc
    11521 cactgtcggg gatccgcaca ccgtcgatcc ttgttccttg ctcgacccgg gggaactgaa
    11581 gcggttcggc aataccgatc tcgatcccga ctacggcaac ttcaaccgct gtgacgtgct
    11641 catccggccc gaggaaggtc ctggtgaggt cgatgtccgg ctgaccttcg agctcgtgcc
    11701 caagaccggc gaggttccgc ctggccagat cgaacgggtc ggtcttgtcc aggtggtcag
    11761 gcatccgatc tacagcgact cgtcgtgcat gcgcagtttg gtcatg
//
