LOCUS       NZ_FWXV01000003        22187 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000003
VERSION     NZ_FWXV01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 193872
            Orig. end                         :: 216059
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22187
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22187
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22187
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12187](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12187)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    39..52
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    173..187
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    complement(454..472)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.15"
                     /tool="antismash"
     misc_feature    complement(1727..1741)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    1925..1934
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.31"
                     /tool="antismash"
     misc_feature    complement(2593..2611)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            complement(2683..3303)
                     /locus_tag="B9C43_RS19920"
                     /old_locus_tag="SAMN05661093_04057"
     CDS             complement(2683..3303)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS19920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_04057"
                     /product="hypothetical protein"
                     /protein_id="WP_084428451.1"
                     /transl_table=11
                     /translation="MSEPKLGLPHRAILLALMAEAREVSNTELKQRWNLTMTKPHRVAL
                     NKAGLMVSNENTTPYRHELTERGWKWCSDELSAEIPARAGSVGAALYAVLAGVNRYLDR
                     EGLALSDLFKSENQIPDLEDRIRRAYERLADRPKAWVRLKDLRPLLGNAPRDAVDDVLR
                     HMDGTADVTIIPDADQKNLTAEDRAAAVRIGNEDNHMLAIGRA"
     gene            complement(3307..4308)
                     /locus_tag="B9C43_RS19925"
                     /old_locus_tag="SAMN05661093_04058"
     CDS             complement(3307..4308)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS19925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_04058"
                     /product="hypothetical protein"
                     /protein_id="WP_084428452.1"
                     /transl_table=11
                     /translation="MTSTLTVTDIAGYLRDSGWQQRQERWRGASIWVYEEQYEVLVPAR
                     DGMGDSDLRVRQIVDTLAQVEDRPTGEIVLDIRMPWSDTQVITMFPHGLPSGFTTLRGG
                     LQALTGVEGALRAAAQSVRGDVPADVERLLGRVQLGPARAGSYILPVRVPVDDDDALGR
                     QVTRRLHTAVSLLSRAQPDPNDLREAEIPAELCESVSRLGNRPFEIGFRWARAIPSDLP
                     TVAYTFAEGAATVIRAAAEQLRRMGDPATVTLTGVIQGLRDDESRDDRWSIEVRGTGRR
                     AVWVRLPDRATYDAAIAAHRAGRQVRVRGEMKTLGRRAELLAGPDGFQLLED"
     gene            complement(4305..4829)
                     /locus_tag="B9C43_RS19930"
                     /old_locus_tag="SAMN05661093_04059"
     CDS             complement(4305..4829)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025638.5"
                     /locus_tag="B9C43_RS19930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04059"
                     /product="DUF4365 domain-containing protein"
                     /protein_id="WP_084428453.1"
                     /transl_table=11
                     /translation="MLDARNHQGKFGEDYVRALASAAGLLVYQHDLDQDGVDLGFRLPG
                     RSTGVASPCIEAQIKSWSRGEIKHGVSEWYFNGLNEAQFNRIAGDDFTVPRFLFLVRVP
                     PDNVDYVEFTTEGMLLRHLAYYCSLRLESPIEHPDKKRKRPVRIPVANVLTTRSLLNLV
                     RSVELIARSTA"
     misc_feature    complement(5116..5129)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.48"
                     /tool="antismash"
     gene            5155..6783
                     /locus_tag="B9C43_RS19935"
                     /old_locus_tag="SAMN05661093_04060"
     CDS             5155..6783
                     /GO_function="GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013673583.1"
                     /locus_tag="B9C43_RS19935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04060"
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="WP_084428454.1"
                     /transl_table=11
                     /translation="MSTDSVPKWRRIAARVITALAFLFVLFALVAPNELSKLSPWSILQ
                     IPLEGLVGVALVLVLPPKPRRIAAVVLGSLLGILLIWKLFDMGFYTTLARPFDPVFDWS
                     FLGPGFEFLAGAIGQGGAVAAAIGISILAVVLVVLMALSAMRLSRVVAGRPTAATRALA
                     VLGVVWVAAAAFGQPFASHSAAALAYDHARQVGSSLQDSNAYNAEASVDAFRDVPGSDL
                     LTGLRGKDVIITFVESYGQVAIQDPELSPAIDSVLDAGTTKLRAAGFESKSAFITSSTS
                     GGGSWLAHSTLQSGVLINNQKRYDTFVGSDRFTLSQAFKRAGWKTVGVVPQNMKPWPEG
                     KVYGYDSYYDSHTSGYKGKNFFYAQMPDQYTLSAFQRNERAKTDRKPVMAEIDLVSSHT
                     PFVPLPEMVDWNAVGDGSIFIPQAENGTKPEEVWNDAGKTRAAYAKSIQYSLNSLISYV
                     QTYGDDNLVVVFLGDHQPAPVITGDDATRDVPVTIVAKDPAVLERTASWGWHDGLNPGQ
                     EAPVWPMQDFRDRFLTSFGPHPPTR"
     gene            6822..7670
                     /locus_tag="B9C43_RS19940"
                     /old_locus_tag="SAMN05661093_04061"
     CDS             6822..7670
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672973.1"
                     /locus_tag="B9C43_RS19940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04061"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_084428455.1"
                     /transl_table=11
                     /translation="MKLGIGLPDHGIVAAARRAEALGFDSVGAADVLIGDGTPAMESVV
                     VQSAVAAVTERVWLDFGLLSIPTRPIAMLAAQIQTLQHLSGNRVRLGLGIGGFPWAPFW
                     HAVNAPTSGRGRLLDQALEVLPTLITGESALGVTLAPAAPVPPLLVGGGNIEPALRRTA
                     KYGDFWVTAALTPAEITEAKAKLAAYAAEYGRPAPRIHLGLHAVLDDEPAREQMVQQLS
                     AFYRKTPEQIAQVTISGSPKQAAERMAEYAEAGLDELGLGSDSGDYLRQLDLIAEARSL
                     L"
     gene            7692..8147
                     /gene="rnhA"
                     /locus_tag="B9C43_RS19945"
                     /old_locus_tag="SAMN05661093_04062"
     CDS             7692..8147
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rnhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020502417.1"
                     /locus_tag="B9C43_RS19945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04062"
                     /product="ribonuclease HI"
                     /protein_id="WP_235038734.1"
                     /transl_table=11
                     /translation="MGEQRVVEIYTDGACSGNPGPGGWGALLRYGQHERELYGGEASPT
                     TNNRMELMAPIKALETLTRPSVVHLYTDSSYVRNGITQWLPKWKSNGWQTSAKQPVKNA
                     DLWQRLEAAATPHEVEWHWVKGHAGHPDNERADQLAVRGCQEAKSVV"
     gene            complement(8136..8891)
                     /locus_tag="B9C43_RS19950"
                     /old_locus_tag="SAMN05661093_04063"
     CDS             complement(8136..8891)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-113). E-value: 1.8e-14. Score:
                     46.0. Matches aSDomain:
                     nrpspksdomains_B9C43_RS19950_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667697.1"
                     /locus_tag="B9C43_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04063"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_084428456.1"
                     /sec_met_domain="adh_short (E-value: 2.1e-33, bitscore:
                     111.7, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADLRDKTALVTGASRGLGRAIARRLAADGATVIVHYGSNAAKAS
                     ETVASISAAGGKAYAVQADLQSADGVDKLFAEISAPLDIVVNNAAVFSSTLFDTTVDEF
                     DRVFAVNVKAPFFIIQKALPLMPDGGRIINISSGVTWFAVPELVYSMTKGALNVLGRSL
                     ANTLGDRQITVNTVSPGTTHSDMNAWLRDNPEAQAGISGITALGRVGEPEDIADAVSLV
                     ASADARWITGEVIEVNGGFYLGPRTPLHH"
     aSDomain        complement(8553..8870)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS19950_PKS_KR.1"
                     /evalue="1.80E-14"
                     /label="B9C43_RS19950_PKS_KR.1"
                     /locus_tag="B9C43_RS19950"
                     /protein_end="113"
                     /protein_start="7"
                     /score="46.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGASRGLGRAIARRLAADGATVIVHYGSNAAKASETVASIS
                     AAGGKAYAVQADLQSADGVDKLFAEISAPLDIVVNNAAVFSSTLFDTTVDEFDRVFAVN
                     VK"
     CDS_motif       complement(8787..8864)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS19950_0001"
                     /evalue="8.20E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9C43_RS19950"
                     /protein_end="35"
                     /protein_start="9"
                     /score="21.7"
                     /tool="antismash"
                     /translation="LVTGASRGLGRAIARRLAADGATVIV"
     gene            8953..9564
                     /locus_tag="B9C43_RS19955"
                     /old_locus_tag="SAMN05661093_04064"
     CDS             8953..9564
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100698.1"
                     /locus_tag="B9C43_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04064"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_235038735.1"
                     /transl_table=11
                     /translation="MIKRHGKGEVMRRTAAETREHILKVAHELFYWHGIRAVGIDKVAA
                     EAGIAPTTLYRIFAAKDDLIAAYVDRSHDSSVAKFTEAADKAGPDPKDQLLAMFDSLIE
                     QMNPAEFRGCACMMTLAEFPDPELPAHQKAIASKTWVRGRISELTARIEGVEDPEKLAD
                     QLVLIWEGANASAQALGVSGPAKHTREFAETTIAAAIGNR"
     gene            9638..10012
                     /locus_tag="B9C43_RS19960"
                     /old_locus_tag="SAMN05661093_04065"
     CDS             9638..10012
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073438.1"
                     /locus_tag="B9C43_RS19960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04065"
                     /product="VOC family protein"
                     /protein_id="WP_033389914.1"
                     /transl_table=11
                     /translation="MDFKLELIAVPVSDVDRAKAFYEQVGFNADHDHTVSEDIRFVQLT
                     PPGSACSIAIGKGLTDVEPGSVKGLQVVVTDIEAAHKVLTERGIEVSEISDMPWGSFVF
                     FSDPDGNAWAVQQIQPRSHS"
     gene            complement(10001..12187)
                     /locus_tag="B9C43_RS19965"
                     /old_locus_tag="SAMN05661093_04066"
     CDS             complement(10001..12187)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165213.1"
                     /locus_tag="B9C43_RS19965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04066"
                     /product="terpene synthase family protein"
                     /protein_id="WP_084429079.1"
                     /sec_met_domain="T1TS (E-value: 6.1e-79, bitscore: 262.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAFTLPDFYMPYPARLNPHLESTRAHSMSWARDMGMLDAPKPDG
                     GVVWTEEVLAKMDYALMCAYTHPDCDGPTLDLITDWYVWVFFFDDHFLEHFKYSRDLSG
                     AREYLDQLERFMTREGETASEPSNPAEAGLKDLWARTVPAMSSDWRERFIRSTHNLMVE
                     SMWELNNINIGRIANPIEYIQMRRRVGGAPWSANLVEYAAAAEVSDRFARTRQFEVLTD
                     TFSDAVHLRNDLFSYQREVREEGENSNAVLVFEKFFGIETQHAAEMVNDLLTSRVQQFE
                     NTALIEVPAVFLAMQALPDEQAKFAGYVKGLQDWQAGGHEWHMRSSRYMNEGAVTETPA
                     VLGGPNGLGTAGITPGRLGLKVRAQQHSFTPFRPVGHLPLPELYMPFPTRVSQHYEAAR
                     DYLVDWGRDMGFYESGVWDERSLKMNDLAYCAARIHPDSDLEELKVSSAWLAWGTLADD
                     YFPAVYGTSRNLAAAKAAVDRLKLFMPLDMGSVPKPVDAIERGLADLWQRSASSMPGPA
                     RTQLRAAVATMLDSWLWELFNQAENRVPDPVDYVEMRRITFGSDLTIGLARIPHWNVIP
                     EEIYQTRVVRELETAAMDYACFTNDLFSYQKEIEFEGELHNIVLVIEQFLGVDRWQARD
                     ITADLMKARMQQFEHILANDFPVLFEEYGLDEEARTMLMDYAGKLKDWMSGVLAWHQEV
                     DRYKEAELRRRQNPSALLPTGPGTSAAWRTALRV"
     misc_feature    complement(12169..12182)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            complement(12299..12733)
                     /locus_tag="B9C43_RS19970"
                     /old_locus_tag="SAMN05661093_04067"
     CDS             complement(12299..12733)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024966.5"
                     /locus_tag="B9C43_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04067"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_084428457.1"
                     /transl_table=11
                     /translation="MDWIEIVDALYRFGRGQDMRDKELFASAFAQDATLDFQPAAAKWG
                     GVSPLMTGRDTIVDTIFAVLSDVDTTHVVTNPRVRIDGDTAQLTAIVEAQHLRSGDHSV
                     YALLKNHYEVGLVRDGSRWVARRIVIDNAWYQGTPTAFFG"
     gene            12820..13656
                     /locus_tag="B9C43_RS19975"
                     /old_locus_tag="SAMN05661093_04068"
     CDS             12820..13656
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="B9C43_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04068"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_084428458.1"
                     /transl_table=11
                     /translation="MERHEVEALLTLAEELHFGRTAQRLHVTTGRVSQTIRQLEHRVGV
                     PLFERTSRKVALTPVGKQLVNDIQPAYEQLRAGLARAIEAGKGLDGELRVGFVGAAAAE
                     MLINAEKVFGRRYPGCAVHLKEMHLGDAPERLRSGEIDIMLGCFPLAAIDLVTGPTLLT
                     ELWMLAAPASHPLARRSHVSTKDLAGQTFLEAPCGLSFDGTRPGPRAETFQEILTLVSA
                     GKGIFAVGEHAIRFHDRPDIAYVPISNAPKLEWGPVWRATNENARVRGFVEALTGA"
     gene            complement(13643..13987)
                     /locus_tag="B9C43_RS19980"
                     /old_locus_tag="SAMN05661093_04069"
     CDS             complement(13643..13987)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944290.1"
                     /locus_tag="B9C43_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04069"
                     /product="VOC family protein"
                     /protein_id="WP_033389918.1"
                     /transl_table=11
                     /translation="MTIRRVVPDVRSADIGASTKFYGLLGFEEVMNHGWVVGLASPSNP
                     TAQVLLTDADPSGLQPDMSVEVSDVDAVHAVLVDQGADIVYAIRDEPWGVRRFFVRDPD
                     GHIVNVLTHR"
     misc_feature    complement(13978..13998)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.4"
                     /tool="antismash"
     gene            complement(13998..14819)
                     /locus_tag="B9C43_RS19985"
                     /old_locus_tag="SAMN05661093_04070"
     CDS             complement(13998..14819)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153250.1"
                     /locus_tag="B9C43_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04070"
                     /product="SCO6745 family protein"
                     /protein_id="WP_084428459.1"
                     /transl_table=11
                     /translation="MRQMWHLLEPVHALVYYAPEVFDELARLGYEVDTRWPTYFPLRSA
                     PLGPASAELVSATFYSFNPDMVAEHISPAWGLASPADVVAARTRGMDRALRRLLGDMDL
                     TEAADLAKKVALAASTAGRPLAAANASLPWPEEPHLVLWHAATIIREHRGDGHIAALLT
                     AGLDPVEALVSFAAVGAAPVEVFASRGWTQRQWADAQRRLHERGWVDADGNATQEGKDG
                     REAVERLTDELAAAPWAVINPGRLAELVMPVTMAAAQSGLLPSKSTLGIRR"
     misc_feature    complement(14679..14681)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14905..15480
                     /locus_tag="B9C43_RS19990"
                     /old_locus_tag="SAMN05661093_04071"
     CDS             14905..15480
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019818824.1"
                     /locus_tag="B9C43_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04071"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_084428460.1"
                     /transl_table=11
                     /translation="MPYHHGDLRRAVLDAALEVIAVDGPSAISLRDLARRAGVSHAAPA
                     HHFKDKAGLLTAIAVEGNELLAESLEQAIAGQCTRLVDLGVRYVRFALDHPGHFAVMYR
                     PDLYHRDAPELIAARERTGKLLRGTVQAIAGDQDARVTQLAAWSAAHGFATLALAGNLD
                     KTIGDQDPTELFRTLADVMFVGRGTIEQ"
     gene            15477..16400
                     /locus_tag="B9C43_RS19995"
                     /old_locus_tag="SAMN05661093_04072"
     CDS             15477..16400
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018331931.1"
                     /locus_tag="B9C43_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04072"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_084428461.1"
                     /transl_table=11
                     /translation="MNDLEQHRIGLTGYCYRMLGASLEAEDAVQETFLRAWRKQDQRQG
                     QLKSWLYAIATNVCLDMLRSAQRRVIAMDIAEPSRAGTEFSDPLPETSWIQPVPDARVL
                     DPANVVAERETIRLAFVAALQYLPPKQRAVLILREVLAWKADEVAELLDTSVASVNSAL
                     QRARATLATRPAAKPLDEDQQQLIERYMQAFTRYDLDTLVTLLHEDATSSMPPFTWWMR
                     GRDELMAALRGAGSEAVCQISTFVPAGFANGAPVYGQYLEGKPFSLQVFEVSGGLITHT
                     TTYLQAGNLFPLFGLPLDEFSDATPS"
     gene            16427..17194
                     /locus_tag="B9C43_RS20000"
                     /old_locus_tag="SAMN05661093_04073"
     CDS             16427..17194
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-145). E-value:
                     1.6e-18. Score: 59.2. Matches aSDomain:
                     nrpspksdomains_B9C43_RS20000_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="B9C43_RS20000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04073"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_084428462.1"
                     /sec_met_domain="PF00561 (E-value: 1e-14, bitscore: 50.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9e-19, bitscore:
                     64.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGYVTVNGVRSWYDVRGAGEPLVLLHGGFSDSRDFDDNLLKLAS
                     KFKIYLLDRRGHGRTPDVEGPVSIEMLVGDVAAFIDEVVGEPAHLAGYSSGGFVALAVA
                     VKRPDLVRKLVLVSTAYDKDGWMFLPEPDAELPPQLVDRYAEVSPDGRDHMPVVVRKFA
                     EMEAGESLKPAEVTSPTLILLADDDMIHLRHTIDMYEAIPKAQLGIVPATSHLLFWERP
                     ELVTRLVEEFLTIQPAPMMPIRRPGGFLSQQQQ"
     aSDomain        16490..16861
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS20000_Abhydrolase_1.1"
                     /evalue="1.60E-18"
                     /label="B9C43_RS20000_Abhydrolase_1.1"
                     /locus_tag="B9C43_RS20000"
                     /protein_end="145"
                     /protein_start="21"
                     /score="59.2"
                     /tool="antismash"
                     /translation="PLVLLHGGFSDSRDFDDNLLKLASKFKIYLLDRRGHGRTPDVEGP
                     VSIEMLVGDVAAFIDEVVGEPAHLAGYSSGGFVALAVAVKRPDLVRKLVLVSTAYDKDG
                     WMFLPEPDAELPPQLVDRYA"
     CDS_motif       16685..16741
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS20000_0001"
                     /evalue="3.20E-07"
                     /label="NRPS-te1"
                     /locus_tag="B9C43_RS20000"
                     /protein_end="105"
                     /protein_start="86"
                     /score="22.8"
                     /tool="antismash"
                     /translation="PAHLAGYSSGGFVALAVAV"
     gene            complement(17100..17999)
                     /locus_tag="B9C43_RS20005"
                     /old_locus_tag="SAMN05661093_04074"
     CDS             complement(17100..17999)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417679.1"
                     /locus_tag="B9C43_RS20005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04074"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_200825618.1"
                     /transl_table=11
                     /translation="MDWLETRELAYFIAVAEELHFGRAAERLRIAQPPLSRAIRQLEQR
                     LGVELFERTSRKVMLTAAGEVLLHEARKALDAVAAAARRTQRVAEPKLVMVMKPGSDGG
                     MLQAILDTYATERDALPVQVQVCAIGEQAQILRDGRADVAVLHLPYDDTSGFDVEQLRV
                     EGAVAILPAGHRYADRDRLWMSDLEGEPMPRWPGMTGTGPEVRDAAQLMQLITLGQMIA
                     VLPESARIGLREDLVAVPVVDGPITTIALGWPERSSSRAVAAFVRAAIAVAEKEIRLDV
                     GSASSARAGLSGTPRPAG"
     gene            18070..18777
                     /locus_tag="B9C43_RS20010"
                     /old_locus_tag="SAMN05661093_04075"
     CDS             18070..18777
                     /NRPS_PKS="Domain: PKS_KR (6-174). E-value: 1.3e-06. Score:
                     20.3. Matches aSDomain:
                     nrpspksdomains_B9C43_RS20010_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227429.1"
                     /locus_tag="B9C43_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04075"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_084428463.1"
                     /transl_table=11
                     /translation="MTEQKIALVTGANKGIGYEIAAQLKALGMTVIIGARDEQRRAQAA
                     QALGVESVALDVTDAGTAEKAAAWIDERFGRLDVLVNNAGVVGGRAQAPTTVDPALVRE
                     VFETNFFGVLTVTNAMLPLLKRSAGARIVNMSSGVGSIGAATAIYGELPAGAAYPPSKT
                     ALNSLTAQYAKDLRGTGILINAADPGYCATDLNNHTGFRTAAQGAAIAVKLATLDDDGP
                     TGGFFNDDGPLPW"
     aSDomain        18088..18591
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS20010_PKS_KR.1"
                     /evalue="1.30E-06"
                     /label="B9C43_RS20010_PKS_KR.1"
                     /locus_tag="B9C43_RS20010"
                     /protein_end="174"
                     /protein_start="6"
                     /score="20.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVTGANKGIGYEIAAQLKALGMTVIIGARDEQRRAQAAQALGVE
                     SVALDVTDAGTAEKAAAWIDERFGRLDVLVNNAGVVGGRAQAPTTVDPALVREVFETNF
                     FGVLTVTNAMLPLLKRSAGARIVNMSSGVGSIGAATAIYGELPAGAAYPPSKTALNSLT
                     AQYAK"
     gene            18794..19408
                     /gene="lipB"
                     /locus_tag="B9C43_RS20015"
                     /old_locus_tag="SAMN05661093_04076"
     CDS             18794..19408
                     /EC_number="2.3.1.181"
                     /GO_function="GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lipB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642606.1"
                     /locus_tag="B9C43_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04076"
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="WP_235038736.1"
                     /transl_table=11
                     /translation="MKRIDLGEVPYLEAIEDMRTWVEQRQNNLIEDRLVLLTHPAVITY
                     GARTPPAELPKHGDIPVIPVDRGGQATYHGPGQLIGYLVIDLRQRGPGDIVRWLENGLI
                     TALDSLGFTLIRRDTPPGSQSLVGVWTPDHRKIASIGMRIRRGVTSHGFSLNITSDLAV
                     YQSFTACGLPGVPMTSLAGLTGDVPSENKVRDAVAAALGAI"
     misc_feature    complement(19742..19756)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(19952..19967)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.31"
                     /tool="antismash"
     misc_feature    complement(20978..20992)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 gcaaaccgcc gagcggccgg tcacctgcgg ggttgcgctt gacccagctg aacagctcca
       61 gctgaagctg gttgacgaag atctgttttt gctcgggtgc tgccagtgct tcgaggttga
      121 tcaccgacac gcgggcacgc ttgcccgccg cgggtgtgaa cagaactccc ggatcgatct
      181 tgtcgatctt gtcgtccagc agggggtcgt tcaccatctc ggcgcgcagg ctctgcgcca
      241 atggtgcggc aatgctggca gcacctgtca gattgctcac gccttcaggc agatcggtaa
      301 ggatgttgat caatccggtc atgctccggc cgccgcagcg tgcgtagtgc tcgatcgcct
      361 gcgtcagcac agctttgccc catttggctt tgtctgtatt gccgtcgacc cgcgctctcg
      421 gtgcgagcgc ggccgctgcc tcccgcactg cgaattcaaa ctcatccgca ttgtcgagca
      481 cgctggcgaa atccggcaac ggttcgaacg caagcggccg tccacctgga cgacctggcg
      541 tccacaccac cacatcggtg tcacgcaagt actcgtctgc cttgtctttg tcctcggcca
      601 caggcaactc gggccacgcg tcaccaagcc tggcgaggtc actgttcgga tcgagcacga
      661 tcgacgagac gccaagcagc gcacactcct cgacaagccg ccggatgagc acggtcttac
      721 cggaacccga tccggcgaag atcacgacgt gcttgcgcag cgactcaagc ggaacactca
      781 ccgacgactg gtcggcaagt agccggccaa ccggcactcg cgccgcacca tcagagtcgt
      841 ccgcgggctg agtcgatctg accggttcgg cgtcctcgat caacgcttcg acgtccaccg
      901 gaaggaccgc ggagaacaac tccgttctgc ttgcgggtcg ttgagcgatc agccagtcgg
      961 acaggcccgg tttcgcctcg ctcagcattt gtcgcagggc gtggaacgtt ctcaagtcgt
     1021 cctcggtgat cggcaccgac gcgccgccgg tcttctcgac attggacagc aaccgccggg
     1081 tctcctgtcc gcgggaccaa tcgatgtttc ggatcaggat caatgcccgg ccagggacgc
     1141 cgaggttgat accggccgcg tcgcaggcct tgtcaagcct ggggaatgct ccttgcgcac
     1201 gggggtgtgc gatggcccgg aacgaccagt gggcctgatc atcggtctcc ttgtccagga
     1261 tgaggcgcag ccgcgcgtgt aagggtggct tcgcgcccgg tgctggatcc accgaccagg
     1321 attgccctgg tccacgctcg gtaacccagg ccgtcagccc cgcgaagagc agcgccggca
     1381 tcacccggtt ctccagatct gggttcagcg gcgccagaat gtcagcgtcc tgcttcaact
     1441 tggcgaaccg ggtatcgaac agttcgtagt cgacatccgg cgttggtgca ggcagcgtga
     1501 cggactcttc gccgaaactt tcggcgaagc tcgtcagctc agtcaccttt ccgcgttgga
     1561 cacaggtctg ggcatgctgg gagatgctgg tcagcacctg ccgaggtgta taggccttga
     1621 catcgtcgaa agcagaaggg gccaccggcc acgttggatg tggaggggtg aaaccgatcc
     1681 gctcatacgc ttgccccagc cgcgcggtca ccaactccct gcccagttcg acgtctgtga
     1741 tcctggacaa ttcgggggcc agcgtgaatc gatcagggac cgacgcggtg gccgtcgtct
     1801 cgatgagagt ccatgactgt ggcagacatg caacgatcgt cagtgtccgc ctggtcacct
     1861 cacgtagatg catcagaccg tccgcgatct ccgcgatctg cctgtcaacc acccccgcga
     1921 cagccgattt ttgagccagc gtcaccaggg tgtcgatctg gtcgatagcg acgacgctgg
     1981 gcccggtgag gccaagcagc ttggacacgt cggacaccac ccggcgtgcc tcatgtggct
     2041 ttgcccgaaa gccccaacgg cgacggtctt cctctcgcat ttcacccgac gacgtcaggt
     2101 agtcataccc gacattcgct tcccgcacat cgacagacgc tgccaacgcc agagcacgcg
     2161 ccgcatcttg gcattccatc gcgacttgcc ggttgagccc tcgcaatgag ccaacgaatt
     2221 catcgagtcc gcccggtgtc aacggtgcat tgccgatgat cgcatcggtc agcgacggca
     2281 gaacacccgc agcagtacag agcctgcgta ggaaggtgga cagttggctc aacccgtctt
     2341 cgccgtcgcg acccagcccc tgcaacagcg cttccgaggc atttgcccaa aatccactgc
     2401 catcacccag attgctcagg aagaagtagc cgccttcgcg tgccatctgt tggcgtaccc
     2461 agccgagtat gtgtgtctta cccgcgccgg cgcggccgct cagcacgaca ccgatcgggc
     2521 taggcccgtt gcttcggctt gcatccctga cccggtccat caccatctgt tgggcagccc
     2581 tgtgcagacc tcgtacgtgg gcctgacctg aatgccaaac gtcctcttcg gtcagaggcg
     2641 cctcgaaccg cagttgtgcc aaagccttgt gctcgtccat ggtcacgctc gaccgatcgc
     2701 cagcatgtga ttgtcctcgt tgccgatccg cactgcggca gcccggtcct ccgcggttag
     2761 attcttctga tcagcatcag gaatgatcgt gacgtcagcg gttccatcca tgtgccgcaa
     2821 cacatcatcg accgcgtcgc gaggtgcgtt gccaagcaag ggacgaaggt ccttgagacg
     2881 cacccatgcc ttgggacggt cagccaaccg ctcgtacgcg cggcgaatac ggtcctccag
     2941 atcgggaatc tggttctctg acttgaacaa gtcactgagc gcgaggcctt cacgatctag
     3001 gtagcggttc acgccggcga gcaccgcgta gagagccgca cccactgatc ccgcgcgagc
     3061 cggaatctcc gcagaaagct cgtcagagca ccatttccaa ccgcgctcgg tcagctcgtg
     3121 gcgatagggc gtggtgttct cgttgctcac catgaggccc gctttgttga gcgcgacgcg
     3181 gtgcggcttg gtcatcgtca ggttccagcg ctgtttgagc tcggtattgg agacttcccg
     3241 cgcctccgcc atcaacgcga gcaagatcgc tcggtgcgga agccccagtt tcggttcgga
     3301 catgcgtcag tcctccagta gctggaatcc gtccggtccg gcgagcagtt ccgcccggcg
     3361 accgagtgtc ttcatctcgc cgcgtacgcg aacttggcgc ccagcgcgat gagcggcgat
     3421 cgcggcgtcg tacgtggcgc ggtcaggcag ccgaacccat acggctcgac gccctgtgcc
     3481 acgcacctcg atcgaccatc tgtcgtcgcg ggattcgtca tcccgcagcc cttggatcac
     3541 acccgtcaag gtcacggttg cggggtcgcc catccggcgc aactgctccg cggccgctcg
     3601 aatcacggtg gccgcgcctt cagcgaaggt gtacgcgacc gtcggcaagt ccgatgggat
     3661 ggctctggcc caacggaatc cgatctcgaa cggtctgttg cccaaccggc tgaccgactc
     3721 gcacaactcc gcggggatct cggcttccct caggtcattc ggatccggct gggccctgct
     3781 cagcagagaa accgcagtat gcagccgtcg ggtcacctga cgaccaaggg catcgtcgtc
     3841 gtcgacgggt actcgcaccg gcaggatgta gctaccggct cgcgcggggc ccagttgcac
     3901 gcggcccagt agacgttcga catccgcagg gacgtcccca cgaaccgact gtgccgccgc
     3961 acgcagcgcg ccctccacac ctgtgagggc ctggagacca cctcgcaacg tggtgaaccc
     4021 tgaaggcagg ccgtgtggaa acatcgtgat cacttgggtg tcagaccacg gcatccggat
     4081 gtcgagaacg atctcgcccg tcggtcggtc ttcgacctgg gccaatgtgt ccacgatctg
     4141 ccggacccgc aggtccgagt cccccatccc atcccgggcg gggacgagta cctcgtactg
     4201 ctcttcgtag acccagatgg acgcacctcg ccaccgctcc tggcgttgct gccagccgct
     4261 gtcccgcaag tagccggcta tgtcggtcac ggtgagcgtg ctcgtcacgc tgtactccgc
     4321 gctatcagtt cgactgaccg gacgaggttc agcaggctgc gcgtggtcaa gacgttcgcc
     4381 acgggtatcc ggacgggacg cttgcgcttt ttgtcgggat gttcgatcgg cgactccagc
     4441 cgaagcgagc agtaataggc aagatgcctc aggagcatgc cctccgtggt gaactcgacg
     4501 tagtccacgt tgtccggcgg aacacggacg agaaaaagga atctcggcac ggtgaaatcg
     4561 tcacccgcga tgcggttgaa ctgcgcttca ttgagaccgt tgaagtacca ttccgagacg
     4621 ccgtgcttga tttcaccgcg cgaccaggat ttgatctgcg cctcgataca cggcgaggcg
     4681 acaccggtgc ttcttccggg cagccggaat ccgagatcaa ctccatcttg atccagatca
     4741 tgctggtaca caagcaaacc ggccgctgac gcgagcgccc tgacgtagtc ctcaccgaac
     4801 ttgccctgat gattccgggc atctagcaca cgacctcccc ggctgtggca gcgagacgca
     4861 gcttacgcaa gttcacacat tcgtgtcagc acaatgaacc cgaacggacc accagctcag
     4921 atcaacattt cctatgacaa gatcgatatt cacctgcgat gacgaatcgt tgatcgcgga
     4981 tacctccgcg gcccggaacg cactcgacta acagcgagca ccgtcccgcg ggatcacgct
     5041 ccggggcgac cggtaacttg gcgtggcggt gaacctcgct ctggcgctgt ccgtactcct
     5101 agtggcggct gcctgcgaaa gttcgtttgg cagatgagca tcggagggca gttgatgagt
     5161 acggacagtg tgccgaagtg gcgtcggatc gcggcaaggg tgatcacggc gctggcgttc
     5221 ctgttcgtgc tgttcgcttt ggtcgcgccg aacgagctca gcaagctgag tccgtggtcg
     5281 atcttgcaga ttccgctcga ggggctggtc ggcgtcgcgc ttgtgctcgt gctgccgccg
     5341 aaaccgcggc ggatcgccgc cgtcgtgctc gggtcgctgc tgggcatcct gttgatctgg
     5401 aagctcttcg acatgggctt ctacacgacg ttggctcgcc cgttcgaccc cgtgttcgac
     5461 tggagtttcc tgggaccggg ctttgagttc cttgccggtg cgatcgggca gggcggggct
     5521 gttgccgccg cgatcggcat ctcgatcctg gccgttgtgc tcgttgtgct gatggcgttg
     5581 tcagcgatgc ggttgtcccg tgtggttgcg gggcggccga cggcagcgac gcgtgcattg
     5641 gctgtgttgg gcgttgtgtg ggttgcggct gccgcgtttg gacagccgtt tgccagccac
     5701 agtgcagcag cgttggcata cgaccatgcg cggcaggtcg gatcgagtct gcaggattcc
     5761 aacgcctaca acgcggaagc gtccgtcgac gcgttccggg atgtgccggg cagcgacttg
     5821 ctgaccgggc tgcgcggcaa ggacgtgatc atcacgttcg tcgagagcta cggccaggtc
     5881 gccatccagg atcccgaact gtcccctgcc atcgactccg tccttgacgc gggcaccacc
     5941 aagttgcggg ccgccgggtt cgagtccaag agtgcgttca tcacctcgtc gacctcgggc
     6001 ggcggcagct ggctcgcgca ctccacgctg cagtccggtg tgctgatcaa caaccagaag
     6061 cgttacgaca cctttgtcgg cagtgaccgg ttcacgctca gccaggcctt caagcgggcc
     6121 gggtggaaga ccgtcggagt cgtgccgcag aacatgaagc cgtggccgga aggcaaggtc
     6181 tacggctacg actcgtacta cgactcccac acctcgggct acaagggcaa gaacttcttc
     6241 tacgcccaga tgcccgacca gtacacgctt tcggcgttcc agcgcaacga gcgcgcgaag
     6301 accgaccgca agccggtgat ggccgagatc gacctggtct ccagccacac cccgttcgtc
     6361 ccgctgccgg agatggtcga ctggaacgcc gtcggcgacg ggtcgatctt cattccgcag
     6421 gccgaaaacg gcaccaagcc ggaagaggtg tggaacgacg cgggcaagac ccgggcggcg
     6481 tatgccaagt ccattcagta ctcgctgaac tcgttgatct cgtacgtgca gacatacggc
     6541 gacgacaacc ttgtagtcgt gttcctgggt gaccatcagc ccgcgccggt gatcacgggt
     6601 gatgacgcga ctcgcgacgt ccctgtgacg atcgtggcga aggacccggc ggtgcttgag
     6661 cggaccgcga gctggggctg gcacgacggc ctcaaccctg gccaggaggc tccggtctgg
     6721 ccgatgcagg acttccgcga ccggttcctg acctcgttcg gcccgcaccc gccgacccgg
     6781 tgagttgact tcaacctagg ttgaggttcc aacctggggt catgaaactc ggaatcggac
     6841 ttcccgacca cggaattgtc gccgccgcgc ggcgtgcgga ggcgttgggc ttcgactcgg
     6901 tcggagccgc ggacgtcctc atcggtgacg gcacacccgc gatggaaagc gtcgtcgtcc
     6961 agtccgcggt cgcggcggtg accgaacgcg tgtggctcga tttcggtctg ctgtccatcc
     7021 cgacgcgacc gatcgcgatg ctggcggcac agatccagac gttgcagcac ctgtctggca
     7081 accgcgtccg gctcggcctc gggatcggag ggttcccgtg ggcacctttc tggcacgcgg
     7141 tcaacgcccc cacgtccggc cgtggccggc tgctggatca ggctctcgag gtgttgccga
     7201 cactcatcac gggcgaaagc gcgctaggtg tcacgttggc gcccgccgcc ccggtgcctc
     7261 cgctgctcgt cggcggcggc aacatcgaac ccgcactccg gcgcaccgcg aagtacgggg
     7321 acttctgggt gacagccgca ctgacaccgg cggagatcac tgaagcaaag gcaaaactgg
     7381 cggcgtacgc ggccgagtac ggcaggccgg cacctcgcat ccacctaggc ctgcacgctg
     7441 tcctggacga cgaacccgcg cgcgagcaga tggtccagca gctcagcgcg ttctaccgca
     7501 agacaccgga acagatcgcc caagtcacga tcagcggcag cccgaaacag gcggccgagc
     7561 gcatggccga gtacgccgag gcagggctgg acgaactcgg tcttggcagc gacagcggtg
     7621 actacctgcg ccaactcgac ctgatcgcgg aggcccggtc gctgctctga accgcccggt
     7681 acggtgctca cgtgggtgaa cagcgggttg tggagatcta caccgacggc gcgtgcagcg
     7741 gaaatcccgg gccgggcggg tggggtgccc tgctgcgcta cggccagcac gaacgcgagc
     7801 tctacggcgg tgaagcgtcg cccacgacga acaaccggat ggagctgatg gctccgatca
     7861 aggccttgga gacgttgacc aggccttcgg tcgtgcacct ctacacggac agttcctacg
     7921 tgcgcaacgg gatcacgcag tggctgccga agtggaagtc caacgggtgg cagacctcag
     7981 ccaagcagcc ggtgaagaac gcggacctct ggcaacggct ggaggccgcg gccactccac
     8041 acgaggtgga gtggcactgg gtcaagggcc acgccgggca tcccgacaac gagcgcgccg
     8101 accagctggc cgtgcggggt tgccaggaag cgaaatcagt ggtgtagcgg cgtgcgtggg
     8161 ccgaggtaga acccgccgtt gacttcgatc acctctccgg tgatccaccg cgcatccgcc
     8221 gatgcgacaa gggaaacggc gtcggcgatg tcctccggct caccgaccct gcccaatgcg
     8281 gtgatgccgg agatgcctgc ttgcgcttcg ggattgtccc gcagccaggc gttcatgtcg
     8341 gagtgcgtgg ttcccggcga cacggtgttc acagtgattt gcctgtctcc caacgtgttc
     8401 gccaacgaac ggcccagcac gttcaacgct cccttggtca tcgagtacac cagctccgga
     8461 acagcgaacc aggtcacgcc ggacgagatg ttgatgatcc ggccgccgtc cggcatcagc
     8521 ggcaacgcct tctggatgat gaagaacggc gccttcacgt tcaccgcgaa gacccggtcg
     8581 aattcgtcca ctgtggtgtc gaacagcgtc gagctgaaca cggccgcgtt gttcaccacg
     8641 atgtccaagg gcgccgagat ctccgcgaag agcttgtcca caccgtcagc ggactgcagg
     8701 tcggcctgga cagcataagc cttcccaccc gccgctgaga tggatgcgac ggtctccgac
     8761 gccttcgccg cgttgctgcc gtagtgcacg atcacggtcg cgccgtccgc cgccagacgc
     8821 cgtgcgatcg cccgccccag acctcgtgaa gcacccgtga ccagcgcagt cttgtccctc
     8881 agatcagcca tgaccaactc cccagacgaa tgttagggga cgttccctaa cgttgctgcg
     8941 gtaaggtagc gcgtgatcaa gcgacacggc aagggggaag tgatgcggcg gaccgcggcc
     9001 gagaccaggg agcacatcct caaggtcgcg catgagctgt tctactggca cggcatccgg
     9061 gcggtcggca tcgacaaggt cgccgccgag gcgggcatcg cccccaccac cctgtaccgg
     9121 atcttcgccg ccaaggacga cctgatcgcc gcgtacgtcg accggtcgca cgacagctcc
     9181 gtcgccaagt tcaccgaggc ggcggacaag gccgggcccg acccgaaaga ccagctcctg
     9241 gcgatgttcg actcgttgat cgagcagatg aacccggccg agttccgcgg ctgcgcctgc
     9301 atgatgacgc tggccgagtt ccccgacccg gagctgcccg cgcaccagaa ggccatcgcg
     9361 tccaagacgt gggtacgcgg ccgtatcagc gagctcacgg cgcggatcga aggcgtcgag
     9421 gacccggaga aactggccga ccagctggtt ctcatctggg agggcgcgaa cgcgtcggcg
     9481 caggcactgg gcgtgagcgg cccggcgaaa cacacgcgcg agttcgctga aacgactatc
     9541 gccgccgcga tcggaaatag gtgacgattg cggccggaaa gtggccgcaa tggctcatag
     9601 gctggtgcca caccgaacga ccgaaggagt ggtccagatg gacttcaagc ttgagctgat
     9661 cgccgttccc gtgtccgatg tggaccgcgc taaggccttc tacgagcagg tcggcttcaa
     9721 cgccgaccac gaccacacgg tcagcgagga catccggttc gtgcagctca ccccgccggg
     9781 atcggcgtgc tcgatcgcga tcggcaaggg cctgaccgat gtcgagcccg gttcggtgaa
     9841 gggtctgcag gtcgtggtca ccgacatcga ggccgcgcac aaggtcctga ccgagcgcgg
     9901 catcgaggtc agcgagatct cggacatgcc gtggggatcg ttcgtgttct tcagcgaccc
     9961 cgacggcaat gcctgggctg tgcagcagat ccagccgcgc tcacactcgt agtgcggtgc
    10021 gccatgccgc ggacgtgcct ggacccgttg gcagcagtgc cgacgggttc tggcggcgcc
    10081 gcagctcggc ctccttgtac cggtcgactt cctggtgcca cgcaaggact ccggacatcc
    10141 agtccttcag cttgcccgcg tagtccatca gcatcgtgcg cgcttcctcg tccaagccgt
    10201 actcctcgaa cagcaccggg aagtcgttgg ccaggatgtg ctcgaactgt tgcatccttg
    10261 ctttcatcag gtcggccgtg atgtcacggg cctgccaccg gtccacgcca aggaactgct
    10321 cgatcaccag cacgatgttg tgcagttcgc cctcgaactc gatctccttc tggtacgaga
    10381 acaagtcgtt ggtgaagcag gcgtagtcca tcgcggccgt ctcgagctcg cgcaccaccc
    10441 gtgtctggta gatctcctcg ggaatcacgt tccagtgcgg gatcctggcc agcccgatgg
    10501 tcaggtccga gccgaacgtg atccgccgca tctccacgta gtcaacggga tccggcacac
    10561 ggttctccgc ctggttgaac agttcccaca accaactgtc caacatggtc gccacggctg
    10621 cccgcagctg ggtacgcgcg ggccccggca tcgaactggc gctgcgctgc cacaagtcgg
    10681 ccaagccacg ctcgatggcg tccacgggct tgggcactga gcccatgtcc aacggcatga
    10741 acagcttgag ccgatccaca gcggccttgg ccgcggccag attcctcgat gtgccgtaca
    10801 ccgcagggaa atagtcgtcg gcgagcgttc cccaggccag ccatgccgac gagaccttga
    10861 gctcctccag atccgagtcg gggtggattc tggccgcgca gtacgccagg tcgttcatct
    10921 tcaggctgcg ctcgtcccac acacctgatt cgtagaagcc catgtcccgg ccccagtcga
    10981 ccaggtagtc ccgagctgct tcatagtgct ggctcaccct ggtcggaaaa ggcatgtaca
    11041 gctccggcaa cggcaggtgc ccgaccggcc ggaacggcgt gaaggaatgc tgctgcgctc
    11101 gcaccttgag cccgagccgc cctggcgtga tgcccgccgt ccccaggccg ttgggtccac
    11161 ctaggacagc cggagtctcg gtgacagcgc cttcgttcat gtaccggctg gaccgcatgt
    11221 gccactcgtg tccgcccgcc tgccagtcct gcaagccctt gacgtacccg gcgaacttgg
    11281 cctgctcgtc cgggagtgct tgcatggcaa ggaaaaccgc gggaacctcg atcagcgcgg
    11341 tgttctcgaa ctgctgcacg cgggaggtca gcaggtcgtt gaccatctcg gcggcgtgct
    11401 gggtctcgat gccgaagaac ttctcgaaca ccaggacggc gttggagttc tccccttcct
    11461 cccgcacttc ccgttggtag gagaacaagt cgttgcgcag gtgcacggcg tcggagaacg
    11521 tgtcggtcag cacctcgaac tgccgggtgc gcgcgaaccg gtcggacacc tcggccgcgg
    11581 ccgcgtactc gaccaggttg gccgaccacg gcgccccacc gacccggcgg cgcatctgga
    11641 tgtactcgat cgggttggcg atccggccga tgttgatgtt gttgagctcc cacatcgact
    11701 cgaccatcag gttgtgggtg ctgcggatga agcgttcccg ccagtcgctc gacatcgcgg
    11761 gcacggtccg cgcccacaag tccttcaacc cggcctcagc agggttcgat ggttcggatg
    11821 ccgtctcccc ttccctggtc atgaagcgtt cgagctggtc gaggtactcg cgtgcgccgg
    11881 agaggtcacg cgagtacttg aaatgctcga ggaagtggtc gtcgaagaag aacacccaga
    11941 cgtaccagtc ggtaatcagg tcgagtgtcg ggccgtcaca gtcgggatgg gtgtacgcgc
    12001 acatcagcgc gtagtccatc ttggccagca cctcctcggt ccacaccacc ccgccgtccg
    12061 gcttcggcgc gtcgagcatc cccatgtccc gcgcccagga catgctgtgt gctctcgtgc
    12121 tctccaaatg agggttcaac ctggccggat acggcatgta gaaatcgggc aaggtgaatg
    12181 cctgcatgaa cgcgccctct cccatcgcga gtcgaccagc accgcatccg acactggcag
    12241 cagacggccg tatcgggata cggccagccg ggcggatgtg accgcacgaa tggctgaatc
    12301 acccgaagaa ggctgtgggt gttccctggt accaggcgtt gtcgatcacg atccgccgtg
    12361 ccacccagcg ggaaccgtcc ctgaccagtc cgacctcgta gtggttcttc agcagggcgt
    12421 aaacgctgtg gtcgccggac cgcaggtgct gtgcctcgac gatcgcggtc agctgggcgg
    12481 tgtcgccgtc gatccgcacg cgcgggttgg tcaccacatg cgtcgtgtcc acatcggaca
    12541 gaacggcgaa gatcgtgtcc acgatggtgt cccgcccggt catcagcggg ctcaccccgc
    12601 cccacttcgc cgccgcgggc tggaagtcca gcgtggcgtc ctgggcgaac gccgaggcga
    12661 acaactcctt gtcacgcatg tcctggccac gcccgaaccg gtacagcgcg tcaacgatct
    12721 cgatccagtc catgtcttca ccctcgccgc tctgacctgc aggaacaacg acggatcggg
    12781 aaacgttcgg ttagtcaggc tcaacgatgg gggcacgcga tggaacgcca cgaggtcgag
    12841 gctttgctga ccttggccga agaactgcat ttcggccgga ccgcgcaacg gttgcacgtg
    12901 accacgggcc gcgtcagcca gacgatcagg cagctcgagc accgcgttgg cgtgccgctt
    12961 ttcgaacgca ccagccgcaa ggtcgcactc acgcccgtcg gcaagcaact ggtcaacgac
    13021 atccagccgg cgtacgagca actgcgagcc ggtctggcca gagcgatcga ggcgggcaaa
    13081 ggccttgacg gcgaactgcg ggtcggcttc gtcggagccg cagcggccga gatgctgatc
    13141 aacgccgaga aggtgttcgg caggcgctac ccgggctgcg ccgtgcacct caaggaaatg
    13201 cacctgggcg acgcaccgga acgcctgcgg tccggcgaaa tcgacatcat gctcggctgt
    13261 tttcccctcg cggcaataga tctcgtgact ggcccgacac tgctgaccga actgtggatg
    13321 ctcgcggcgc ccgccagcca tccgctggca cggcggtcgc acgtgtccac gaaagacctg
    13381 gccggacaga cgttcctcga ggcgccgtgc ggactttcct tcgacggaac tcgccccggg
    13441 cccagggcgg agacgttcca ggagatcttg acattggtca gcgcgggcaa ggggatcttc
    13501 gcggtcggcg aacacgcgat ccgcttccac gaccggccgg acatcgctta cgtgccgatc
    13561 tccaacgcgc cgaagctcga atggggaccg gtctggcgtg cgacgaacga gaacgcgcga
    13621 gtccgcggct tcgtcgaagc gctcaccggt gcgtgagcac gttgacgata tgaccgtccg
    13681 gatcacgcac gaaaaatcgc cgtacgcccc acggctcatc acggatcgcg tacacgatgt
    13741 cggctccctg atccacgagc acagcgtgca cggcatctac atcggacact tcgacggaca
    13801 tgtccggttg caggccggac ggatccgcgt cggtcaacag gacctgggcg gtcgggttgc
    13861 tcggtgatgc gaggccgacc acccagccgt ggttcatcac ttcctcgaac cccaacaggc
    13921 cgtagaactt cgtactggcc ccgatgtcgg cactgcgaac atcggggacc acccgtcgaa
    13981 tcgtcatgcc ggcgagacta acgccggatc cccagcgtgc tcttggaagg aaggaggccc
    14041 gactgggccg ccgccatcgt caccggcatc accagctcgg ccagcctgcc tgggttgatc
    14101 accgcccatg gggccgcagc gagttcgtcg gtgagtcgct cgaccgcttc cctgccgtcc
    14161 tttccttcct gtgtggcgtt tccgtcggca tccacccagc cacgctcgtg cagcctgcgc
    14221 tgtgcatccg cccactgccg ctgggtccag ccccggctcg cgaagacctc gaccggtgcg
    14281 gcgccgacgg cggcgaagga caccaaggcc tcgaccgggt ccagcccagc ggtgagcagt
    14341 gcggcgatgt gcccgtcgcc gcggtgttcc ctgatgatcg tggccgcgtg ccacaacacg
    14401 aggtgcggtt cctccggcca cggaagggac gcgttcgccg cggccagtgg acgacctgcg
    14461 gtgctcgccg ccagcgcgac cttcttggcc aggtcggccg cctcagtcag gtccatgtca
    14521 ccgaggagac ggcgtagcgc ccgatccatc ccacgagtcc gtgccgcgac cacatcggcg
    14581 ggcgatgcga ggccccaggc aggggaaatg tgctcggcga ccatgtcggg gttgaagctg
    14641 tagaacgtgg ccgagaccag ttcggcactg gccgggccta agggcgcgga cctcagcggg
    14701 aaataggtcg gccagcgggt gtcgacctcg tacccgagtc tggccagctc gtcgaagacc
    14761 tcgggcgcgt agtagacgag cgcgtgcacg ggttcaagca agtgccacat ctgccgcatg
    14821 gaaacctcca ctatctattt gtggccaaga taggagcctg ggtcgcatct tgtcaatgac
    14881 aagattggga gtatcgtgcc ggtcatgccc tatcaccacg gcgacctgcg ccgggctgtg
    14941 ctcgacgccg cactcgaggt catcgcggtc gacggcccca gcgcgatcag tctgcgggac
    15001 ctcgcccgcc gcgcaggcgt gtcgcacgcc gcgcccgccc accacttcaa ggacaaggcc
    15061 gggctgctga cagcgatcgc cgtggagggt aacgagctgc tggccgaatc gctagaacag
    15121 gccattgccg ggcagtgcac ccggctggtc gacctcggcg tgcggtacgt gcggttcgcg
    15181 ctcgaccacc ctggccactt cgccgtcatg taccgcccgg acctctacca ccgcgacgcg
    15241 cccgagttga tcgccgcgcg tgagcgcacc ggaaagctgt tgcgcggaac cgtccaagcg
    15301 atcgccggag accaggatgc gcgggtgacc cagctcgcgg catggtcggc cgcgcacggt
    15361 ttcgccacgc tggcgttggc aggcaatctg gacaagacaa tcggcgacca ggaccccacg
    15421 gaactgttcc gcacgttggc cgacgtgatg ttcgtgggtc gtggcacgat cgagcaatga
    15481 acgatctcga gcaacaccgg atcggactga ccggctactg ctaccggatg ctcggcgcgt
    15541 cgctggaagc cgaagacgcg gtgcaggaga cgttcctgcg ggcatggcgc aagcaagacc
    15601 agcgccaagg ccagctgaag tcctggctgt acgcgatcgc gaccaacgtc tgccttgaca
    15661 tgctgcgcag tgcccagcgc cgggtgatcg cgatggacat cgccgaacct tcgcgcgcag
    15721 gcacggagtt cagcgatcca ctgccggaaa cctcttggat acagccagtt ccggacgccc
    15781 gtgtgctcga tccggccaat gtcgtggccg agcgggagac catccggctg gcgttcgtcg
    15841 ccgcactgca atacctgccg cccaagcaac gcgcggtgct gatcctgcgg gaagtgttgg
    15901 cgtggaaggc agacgaggtc gccgagctgc tcgacaccag cgtcgcttcg gtgaacagtg
    15961 cgctgcaacg agcgcgggcg acgctcgcga cgcggccggc cgcgaagccg ctcgacgagg
    16021 accagcaaca actgatcgag cggtacatgc aggccttcac gcgctacgac ctcgacacgc
    16081 tcgtgacgtt gctgcacgag gacgccacgt cgagcatgcc gccgttcacc tggtggatgc
    16141 gtggccgtga cgagctcatg gcagccctgc gtggcgccgg gtccgaggcg gtctgccaga
    16201 tctcgacgtt cgtgcccgcc gggttcgcca acggcgcgcc ggtgtacggc cagtacctcg
    16261 aaggcaagcc gttctcgttg caggtcttcg aggtctccgg cggactgatc acgcacacga
    16321 cgacatatct gcaggccgga aacctttttc cgctgttcgg cctgccgctc gatgagtttt
    16381 ccgacgccac gccgtcctag gtagtaaacc tggcgaaagg acactcgtgg ccggttacgt
    16441 gacagtcaac ggcgttcgct cctggtatga cgtgcgcggt gcaggagaac cgctcgtcct
    16501 gctgcacggc ggcttctccg actcacggga cttcgacgac aacctgctga agctggccag
    16561 caagttcaag atctacctgc tggaccggcg tggccatggg cgtacgccgg atgtcgaagg
    16621 cccggtcagc atcgagatgc tcgtcggtga cgtggccgcg ttcatcgacg aggtcgtcgg
    16681 cgagcccgcg cacctggccg gctacagctc cggcgggttc gtcgcgctcg cggtcgctgt
    16741 caagcggccg gacctggtgc gcaagctcgt gttggtgagc accgcgtacg acaaggacgg
    16801 ctggatgttc ctgcccgagc cggacgccga actcccgccg cagctggtcg accgctacgc
    16861 cgaggtctca cccgacggcc gggaccacat gcctgtggtg gtacggaagt tcgccgagat
    16921 ggaagcaggc gaatcgctca aaccagccga ggtgacaagc ccgaccctga tcctcctcgc
    16981 cgacgacgac atgatccacc tgcgccacac catcgacatg tacgaggcga tcccgaaggc
    17041 acagctgggg atcgtgcccg cgacgtcgca cctgttgttc tgggaacggc ctgaactggt
    17101 cacccggctg gtcgaggagt tcctgacaat ccagcccgcg ccgatgatgc cgatccgacg
    17161 tccaggcgga tttctttctc agcaacagca atagccgctc gaacgaacgc cgcgacggcc
    17221 cgagacgacg aacgctcggg ccatccgagc gcgatcgtcg taatcggacc gtccacaacg
    17281 ggcactgcga ccaagtcctc acgcaggcca atccgagccg attccggcag tacggcgatc
    17341 atctggccga gcgtgatcag ctgcatcagc tgtgcggcgt cgcgaacttc cgggccagtc
    17401 ccggtcatgc cgggccagcg cggcatcggt tcgccctcca gatcggacat ccacaggcgg
    17461 tcccggtcgg cgtaccggtg cccggcgggc aggatcgcga ccgcgccttc gacccgcagc
    17521 tgctcgacgt cgaagccgga cgtgtcgtcg tacggcaggt gcaggaccgc gacgtcggcc
    17581 cggccgtccc gcaggatctg cgcctgctcg ccgatcgcgc agacctgcac ttgcactggc
    17641 agcgcgtcgc gttcggtggc gtaagtgtcc aaaatggcct ggagcatgcc gccgtcactg
    17701 cccggtttca tgaccatcac cagcttcggc tcggcgaccc gctgggttcg ccgggccgct
    17761 gcggcgaccg cgtccagggc tttgcgggct tcgtgcagca ggacctcacc ggctgcggtg
    17821 agcatgacct tgcggctggt tcgttcgaac aactccacac ccaggcgttg ttcgagctgg
    17881 cggatcgcgc gtgacagcgg cggctgggcg atccggagcc gttcagcggc cctgccgaag
    17941 tgcaactcct cggcgaccgc gatgaagtag gccaactcgc gggtctccag ccaatccata
    18001 cctggagggt atcgctgcac accaagccgg tcatggcggt tccgtagtcg gaggtggtga
    18061 gctggaggca tgacagaaca gaagatcgcg ttggtgaccg gtgccaacaa aggcatcggt
    18121 tacgagatcg ccgcgcagct caaagcgctg ggcatgacgg tgatcattgg cgcgcgcgac
    18181 gagcagcgcc gcgctcaagc ggcgcaggcc ctgggcgtcg agtccgtggc actcgacgtg
    18241 accgacgccg ggaccgccga gaaagccgcc gcgtggatcg acgaacgctt cggcaggctg
    18301 gacgtgctgg tgaacaacgc cggggtcgtc ggcggacgtg cccaagcgcc gaccacagtc
    18361 gaccccgccc tggtccggga ggtgttcgag accaacttct tcggcgtcct cacggtcacg
    18421 aacgcgatgc tgccgttgct gaaacgctcg gccggtgccc ggatcgtgaa catgtccagc
    18481 ggtgtcggtt ccatcggcgc cgcgactgcg atctacggcg aattgccggc gggcgcggct
    18541 tatccgccgt cgaagaccgc gctgaactca ctcaccgccc agtacgccaa ggatctccgc
    18601 ggcacgggca tcctgatcaa cgcggccgac ccgggttact gcgcgacgga tctcaacaac
    18661 cacacgggtt tccggaccgc ggcccaaggc gcggcgatcg ccgtcaagct cgccaccctc
    18721 gacgacgacg gcccgaccgg cggcttcttc aacgacgacg gtccgctgcc ctggtaggac
    18781 tagcctgggg gacgtgaagc ggatcgatct gggggaagtg ccgtacctcg aagcgatcga
    18841 ggacatgcgc acctgggtgg aacagcggca gaacaacctg atcgaggacc gtctggtcct
    18901 gctgacacat cccgcggtga tcacctacgg cgcccgcaca ccacccgccg agctgccgaa
    18961 gcacggtgac atcccggtca tcccggtgga tcgcggcggg caggcgacgt accacgggcc
    19021 tgggcagctg atcggctacc tggtcatcga cttgcgtcag cgtggtcccg gcgacatcgt
    19081 gcggtggttg gaaaacggcc tgatcaccgc gcttgactcg ctggggttca cgctgatccg
    19141 ccgcgacacg ccacccggca gccagagcct ggtcggcgtg tggacgccgg atcaccggaa
    19201 gatcgcgtcg atcgggatgc gcatccgccg tggcgtgacc agccacgggt tctccctcaa
    19261 catcacgtcc gacctggcgg tctaccagtc gttcacggcg tgtggcctgc ccggcgtgcc
    19321 gatgacgtcc ttggccggac tgaccggtga cgtaccgtcc gaaaacaagg tccgggatgc
    19381 cgtcgccgca gccttgggcg ccatttgacc taatccgctc ctgtccgaac tgatgcccgt
    19441 tcgggcgggt gataccggcc tgaagcgcca tagtttggcc acgtgccgcc tgatcgtccg
    19501 gccctgacca cggagcctgc cgccgctccg gtgcagcaac cagcgaccgt ggcgcctcag
    19561 gcacagtcgc cggccgaggc attgctggcg ctgcaaggga tggcgggcaa cgcggccgtc
    19621 tcgcggatga tgtcgagccc ggttccggtc acgatcgcgc cgccgagttc acccgaattc
    19681 ctcagcctgg tcgcggacat cgaggcccgg cgagcggcga tcctggcgca cagcacggcc
    19741 caggccgacc agatccgggc cagcgcggac acgttgaagc agcgtttccg taccacggca
    19801 gacaccaagg cgatggccgt cgagcaggcg cacgcagccg ctcttggggt ggtccagcag
    19861 cacgcgtcca ctgcccaggc gaccatccag agcaacctcg acgccgagct ggcccgggtg
    19921 gatgccgccg cggaagccga gctgcaacgc cttgaccaga cgatcgagga caaacgcggc
    19981 acgctcgccc ggcacgccga ggacaaggcc accctggccg ccaccgcagg caccgaacag
    20041 gcccaacgag ccaccgacgg cacagctgag cggactgctc gcgcgaacga aatcgccaac
    20101 gccaagattg agcggtaccg gacgcacgag caggcaggcg acatccgtga cacggtggac
    20161 tcggccaagc gggacgtcat cgccgagctg aaccggaccg gcacggccgt ggccaccagt
    20221 gtccggacca agtcgaccga gctcggcggg cacttccggg aagaggccgc gcagacggca
    20281 cgggatttcg accagccacg caccgacgcc cgtgcccaga tcctggagaa ccgggaccgc
    20341 accaaggaca cgcttcgcga gatcgcggcc aacgcgaccg cccggatcac ctcggaagcc
    20401 aaccagctcg gcacgtcgct gcaggaggag tccacccggc gcgccgtgga gatccgcgct
    20461 caggcagcgt tgttcgactc gtcgatcgac gagtccgtgg cggccacgat cacccagctc
    20521 gccgagcccg ccgaggcact cgccaacgac ctggccggat tcgcacagga caaccaggat
    20581 gccgcgtgct atccgccgtt cgtcgacgag gcgcgcgccg aactgttggc cgcggcgagc
    20641 gaacgggaag cccagatcga cgacctggcc acgcagttcc tcggcagctt ggaccagacc
    20701 accggcgacg ccgagaccac cctcaacgac cacgctgaag cgctgatcag cggcgttcag
    20761 caggcgggcg acgacttcgg cggcccgatc aacgagatca tgcagaacac cgcccaggaa
    20821 atgcacgacg cggccgacga gggcgcgcgg agcatggccg tggtcaccga cgaggtcggc
    20881 cgcgagctgg accgcgtcgt cgaggacctg gattcccgtt gggacgaacg gctttccgac
    20941 cacacccgcg aactgcgcga agaggtcgac aacgcactgg ccgacgaaga ccgtgcggta
    21001 caggggttct ccgacgagat cgacgtcagc gtcgaccgga tcgtcgagga gagcggcttc
    21061 ttcgactcgc tgtggaactt ctgcgccggt ctggtcgagg ggatctggaa cggcctggtc
    21121 gggctgctca agggcatctg ggacgcgatc aagacaccgc tgttctggat cgcggtcgcg
    21181 gtcgtcgtgg tcatcatcgc catcgccgtg atcgtgttgg tgatcaaggg cgcggcggtg
    21241 ctcgcggcga tcggcgcggt gctggcgttc gtcgggaagg tactgctggt catcggtgtg
    21301 atcgtgggca gcatcgccgc gctgtactac ctgtacctgg cgatcacgcg accggacctg
    21361 acctggcggc aacgcggcga actggtcggc cgtgcgatct tcgaggccgc gctggcgttc
    21421 gccggaaccg ggatcctggc ccggctcaag gtgttcgcgc aggtcgcgaa gttccgtgcg
    21481 ctggtgacca gggtcggcag cctggcgctg gcgatcaggc tggtcaacaa ggtgcccgac
    21541 ctcgagaaga tcgccaggct gctggtcctg gccgaggccg cgaacgtgtt gcgggtgctg
    21601 gacaaggtct ccgacgccga actcgcgatc gtcctgctcg gcaaggtgcg cgacatcgac
    21661 gagctgcttg tcctgctgga caagtgttcc gacgcctcga cactggcccg gctgcccgaa
    21721 ctgatcgacg cgttcgacca acggctgctg ctcagggtcg ccgccgagat cgacttccgt
    21781 gacctgctgc ccttcttgga ccagcaggaa acggctgcgg cacgccagat cctcacccag
    21841 tacgccgacg caggcagctg ggacaggctg cgcaggttcc tgcgtggcat gggccaagcc
    21901 gccgagaccg agggctacgc cgcggcaggc gcgggcgaca tcatcgtgga caaccagacg
    21961 ctctcagccg ttcgcgcgat gctcgggggc gtggactacg gcaccctgca gccgatcgag
    22021 cagcgcatga tccagcaact gttcgcccag ctcggtcagc cactcgacgc gaccggaaca
    22081 ctcgtcccac cgaaccagcc ggcgatccag ggaatcatgg gccggttgcg ggcacccgtc
    22141 acagtcatgg gcgagaccgg cgtcaacgcc gtgcacaagc ctctggg
//
