LOCUS       NZ_FWXV01000003        21041 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000003
VERSION     NZ_FWXV01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 67003
            Orig. end                         :: 88044
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21041
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11041](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11041
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(179..1294)
                     /locus_tag="B9C43_RS19325"
                     /old_locus_tag="SAMN05661093_03940"
     CDS             complement(179..1294)
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_3: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079056.1"
                     /locus_tag="B9C43_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03940"
                     /product="sulfotransferase"
                     /protein_id="WP_084428375.1"
                     /transl_table=11
                     /translation="MDIESLHASATKITGLTDFGDSGYLEGLSVLLDSYHREAGLTELG
                     LRVKRAGLRSALVARLLSEAAWQRLPDYASVPIERPIFVTGLPRTGTTALHRLLTEDPA
                     HQGLELWLTDVPQPRPPRETWDENPMYQRIQAGYEQHHVEHPEFMGLHYITADMAEECW
                     RLLRQSMMSISFECLAYVPTYSAWLAEQDWTEAYHRHRRNLQLIGMPDASKRWVLKNPS
                     HLFALDALLDAYPDALIIQTHRAPSTIIASMCSLAEQASGEWSTVFHGSVIGETQLELW
                     ARGLEKFNADRAKHNPAQFYDVQYDDFVADPLSVVTDIYTHFGMDISDDVLDAMKAVHT
                     SGDRRRSHRYDLADFGLTAEQAEARFRSVSP"
     misc_feature    complement(1157..1159)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1304..2080)
                     /locus_tag="B9C43_RS19330"
                     /old_locus_tag="SAMN05661093_03941"
     CDS             complement(1304..2080)
                     /NRPS_PKS="Domain: PKS_KR (6-176). E-value: 2.4e-10. Score:
                     32.6. Matches aSDomain:
                     nrpspksdomains_B9C43_RS19330_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418700.1"
                     /locus_tag="B9C43_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03941"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_033389434.1"
                     /sec_met_domain="adh_short_C2 (E-value: 1.7e-34, bitscore:
                     115.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQDKVVVVSGIGPGLGRSIALRCARQGADIVLAARTESRLTEV
                     AKEVTDLGRRAVTVTTDISSEDDAARLAETALESFGRVDTLVNNAFAMPPMTTFDRAPF
                     EGIRDGFETNVLGALRLVNLFRPALEASRGSIVMVSSMVIRHSQLTMGPYKMTKSALLA
                     MAQSLSTELGPKGVRVNTIAPGYIWADNVKFYFDYLAKQRGITPQEVYDEVAANIDLRK
                     LPEPDEVADTIVFLASSLASAVTGQCLDVNGGEYHH"
     aSDomain        complement(1553..2062)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS19330_PKS_KR.1"
                     /evalue="2.40E-10"
                     /label="B9C43_RS19330_PKS_KR.1"
                     /locus_tag="B9C43_RS19330"
                     /protein_end="176"
                     /protein_start="6"
                     /score="32.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVVSGIGPGLGRSIALRCARQGADIVLAARTESRLTEVAKEVTD
                     LGRRAVTVTTDISSEDDAARLAETALESFGRVDTLVNNAFAMPPMTTFDRAPFEGIRDG
                     FETNVLGALRLVNLFRPALEASRGSIVMVSSMVIRHSQLTMGPYKMTKSALLAMAQSLS
                     TELGPKG"
     CDS_motif       complement(1970..2056)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS19330_0001"
                     /evalue="5.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9C43_RS19330"
                     /protein_end="37"
                     /protein_start="8"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VVSGIGPGLGRSIALRCARQGADIVLAAR"
     gene            complement(2080..3243)
                     /locus_tag="B9C43_RS19335"
                     /old_locus_tag="SAMN05661093_03942"
     CDS             complement(2080..3243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659116.1"
                     /locus_tag="B9C43_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03942"
                     /product="hypothetical protein"
                     /protein_id="WP_084428376.1"
                     /transl_table=11
                     /translation="MLTESFAAAVAEAEKLITQAPHVQTDQDLTEGYDYLAGSIRASLQ
                     MAWAYDRDFPYFVQSTGPYTKMGLDNPDTLYFHAYIREDAEYVVTGKRGSTADLSFQVL
                     NGDYSPVDVPDSLTAFDDREFDIAEDGSFEIRFGPGKAGRNYFTLGDGSAMLIVREVYS
                     DWTGEERGMIKIRRTDTTGSAPPAPTKDLMAKRYTVAGKILIGRIKTFLAFPKWFYLKL
                     PVNTMTEPRLTPGGLATQFSSVGHYDLADEEAMIITVPASEAPYQGFQLGSMWYISLDY
                     INHQTSLTADQARIDPDGKIRYVVSERDPGLVNWIERTGHAKGYLQIRWQRLSRDLKPS
                     DGPAVEVVPVSELARKLPFHEDARITPAEYKDRIAARQAAVATRMVG"
     gene            complement(3276..3743)
                     /locus_tag="B9C43_RS19340"
                     /old_locus_tag="SAMN05661093_03943"
     CDS             complement(3276..3743)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079048.1"
                     /locus_tag="B9C43_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03943"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_033389432.1"
                     /transl_table=11
                     /translation="MDDLHVIEEIRRLKYRYLRGVDQKRWDLLEDALTEDAVADYGTKA
                     MGEPLVLTGRAAILDFMRQNLGGDKIITFHFAGQPEIDVDGDSATGTWAFEDTVIVKEH
                     RLVIKGAAYYEEQYVRSPEHGWRIKHIAYNRLYEAMVSWDDLPSLKFLAGV"
     misc_feature    3790..3799
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            3799..4713
                     /gene="cysD"
                     /locus_tag="B9C43_RS19345"
                     /old_locus_tag="SAMN05661093_03944"
     CDS             3799..4713
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637152.1"
                     /locus_tag="B9C43_RS19345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03944"
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_200825653.1"
                     /transl_table=11
                     /translation="MVATTYELSNLRALEAESAHVLREVAATFERPVLLFSGGKDSVVM
                     LHLAAKAFWPAPPPFPVMHVDTGHNFDEVIEFRDRTVESTGVRLVVSHVQDDIDAGRVV
                     EETGPRASRNRLQTTALLRAINENRFDAVFGGARRDEEKARAKERVFSFRDEFGQWDPR
                     NQRPELWNLYNGRHRRGEHIRVFPLSNWTELDIWQYIRDERIELPEIYYAHRRQVFQRD
                     GMLLAHTRFVTLLPGEEPFEASVRFRTVGDATCTGCVESTAATPEEVVAEVAATRVTER
                     GATRADDRISEAGMEDRKKEGYF"
     gene            4713..6545
                     /gene="cysC"
                     /locus_tag="B9C43_RS19350"
                     /old_locus_tag="SAMN05661093_03945"
     CDS             4713..6545
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637153.1"
                     /locus_tag="B9C43_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03945"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_033389430.1"
                     /transl_table=11
                     /translation="MNQLLRLATAGSVDDGKSTLIGRLLFDSKTIFEDQLAAIERSSRD
                     RGEDYPNLALLTDGLRAEREQGITIDVAYRYFATPKRKFIIADTPGHIQYTRNMVTGAS
                     TADLALILVDARKGILEQSRRHAFLASLLGIPHLVVCVNKMDLVGWSRERFEEIREEFR
                     QFSMKLTVPDLTFVPVSALHGDNIVHRSASMPWYEGTSLLHHLEEVHISSDRNLIDARF
                     PVQYVIRHKDFRGYAGTVAGGVFKPGDEVLVLPSGFTTTVQAIWGLGGQPVAEAFPPQS
                     VTLELADELDVGRGDLICRPNNRPHVGQDVDAIVCWLTERTDLTPDARYTVVNTTRSTK
                     AVVKSLDYRLDITTLHRDDTAESLSLNEIGRVKLRTQQPLLFDAYRRNRACGSFILVDE
                     TSNNTVAAGMITGPSQAVVWHSTAVQRTERGSVGCTVWLTGLSASGKSTVAVELERRLV
                     ASGRPAYLLDGDNLRHGLNADLGFGAADRAENVRRAGEVAKLFADAGVVAVVSLISPYQ
                     ADRDRVRAMHEQAGLPFVEVFVDTPVEVCEARDPKGMYAKARAGEITGFTGVDDPYEVP
                     VAPELVLRPEQGDPARMAALILASMDQVTLTRMD"
     misc_feature    complement(6660..6675)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    6792..6807
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            6876..8291
                     /locus_tag="B9C43_RS19355"
                     /old_locus_tag="SAMN05661093_03946"
     CDS             6876..8291
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020423482.1"
                     /locus_tag="B9C43_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03946"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_033389429.1"
                     /transl_table=11
                     /translation="MTDTVESNLGVENGQQQQSLATAAARNLATTTKSVPQMQSITSRW
                     LLRVLPWVQAQGGVYRVNRRLSYTVGDGRIAVSNTGSRVQVVGPDLVEMALLRTFEDED
                     ALNALAGRFEQQEYEPGAVIAEFGHEADYVYVVAHGKVNKIGTGEYGDQTVLGTMVDGD
                     YFGDQALIQDQSIWEFTAKAVTPTTILALPKQAFQELQDQSEALREHVNAYRNSPKKPA
                     NPYGEAEIELASGHDGEPDLPSTFVDYELSPREYELSVAQTVLRVHTRVADLYNQPMNQ
                     TEQQLRLTIEALRERQEHELINNRDFGLLCNADLKQRIPTRSGPPTPDDMDELLATVWK
                     DPMFILAHPRAIAAFGQECNKRGLYPQSIDLNGHQVPSWRGIPVLPCNKIPVSNTRTTQ
                     MIAMRVGEQNQGVIGLHQTGLPDEYQPGLSVRFMNINEKAIISYLVSAYYSAAVLVPDA
                     LGVLENVELGRTD"
     gene            8608..9996
                     /locus_tag="B9C43_RS19360"
                     /old_locus_tag="SAMN05661093_03947"
     CDS             8608..9996
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334401.1"
                     /locus_tag="B9C43_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03947"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_407657106.1"
                     /transl_table=11
                     /translation="MTQVENPQSQQMSLGTAAARNLATTTKSVPQMQGITPRWLLRVLP
                     WVQAEGGTYRVNRRLTYAIGDGLVSFTSSAGRVQVVPPELRELALLHDLDDDETLAALA
                     GRFEQQEFEPGDLIIQRGGHADRLVLMAHGKADKIGQGEYGADTVLDTIGEGEYFGEQA
                     LTGLRDEWSFSIKAKTPCITLSLSRQDFDRITEQSDKLRAHLEYFVSLRGKRSNAKGEA
                     EIELSSGHEGEALLPATFVDYELSPREYELSVTQTVLRIHTRVADLYNQPMNQTEQQLR
                     LTVEALRERQEYEMINNRQIGLLHNADLKQRIPTRTGPPTPDDMDELISRRRKTQFILA
                     HPKAIAAFGRECNSRGIYPNTKELDGKIVRTWRNIPLLPCDKIPVSETGRTSIIAMRTG
                     EKNQGVIGLHHAGLPDELEPGLNVRFMGVNEKAIMSYLVSAYYSVAVMVPDALGILESV
                     ELGR"
     gene            10001..11041
                     /locus_tag="B9C43_RS19365"
                     /old_locus_tag="SAMN05661093_03948"
     CDS             10001..11041
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944750.1"
                     /locus_tag="B9C43_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03948"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_084428377.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.9e-65, bitscore:
                     216.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLREVTTESRQPGEVLAWSRDMVDPATRAAVGTLPGSMRHIAGY
                     HYGWWDETGTPTETSGGKALRPTLTLLAAEAVGGVASAAVPAAVAIELVHNFSLLHDDV
                     IDGDVTRRHRPTAWSVFGRSAAILAGDSLLTLAFDVLAASGHPDSREGMRILSAAVQSL
                     VEGQSLDVAFEDRQDIELAECEVMARGKTGALISAACAIGALFGGARSAQVEHMRAFGA
                     ELGLAFQLVDDLLGIWGDPAVTGKPVYSDLHNRKKSLPVVAALRSKTTAAQELHELYHA
                     DRPLSGVDVERAAALIDAAGGQAWCQAQADDRLARAIHRLRSADPVAGAAAELAGLACL
                     VTHRDH"
     misc_feature    10193..10195
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11101..12027
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="B9C43_RS19370"
                     /old_locus_tag="SAMN05661093_03949"
     CDS             11101..12027
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010311801.1"
                     /locus_tag="B9C43_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03949"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_084428378.1"
                     /transl_table=11
                     /translation="MQVKVLLASPRSFCAGVERAIEIVEEVLRHRKPPVYVRKQIVHNK
                     HVVADLATRGAVFVDELDAVPDGATVVFSAHGVSPAVREEAERRRLDVIDATCPLVTKV
                     HTEARRFAGRGDTVVLVGHAGHEEVEGTLGEAPDRTVLVQTAEDVASLDIPDPSRVSYL
                     MQTTLAVDEAAEVVSALRARFPDLRGPASDDICYATTNRQNALHAIADEADLVLVVGST
                     NSSNSVRLVELAQRHGTPAYLIDDVSDIKARWLEGVRVIGITAGASAPPGLVDEVVAAL
                     NPISVENRETVTETIQFTLPPAARRSS"
     gene            12024..13742
                     /locus_tag="B9C43_RS19375"
                     /old_locus_tag="SAMN05661093_03950"
     CDS             12024..13742
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666920.1"
                     /locus_tag="B9C43_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03950"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_084428379.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3.5e-84,
                     bitscore: 278.1, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.2e-07, bitscore:
                     25.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGPADLAAKSTSELATVANDIRDFLIRKVSRTGGHLGPNLGAV
                     ELTIALHRVFHSPHDVLLFDTGHQAYVHKILTGRESDFDSLRQAGGLSGYPSRSESEHD
                     VIENSHASTALSYADGWAKAFALQQSTRRVVAVIGDGALTGGMAWEALNNIGSAPDRPV
                     VIVLNDNGRSYAPTIGGIASHLAVLRYEGDRNIFEDLGLAYIGPVDGHDITDLEHALRK
                     AVRLNRPVVVHCLTRKGKGYAPAEEDEADRLHAVGPVGAAKKRSWTSVFAEEITAIGAE
                     REDIVCITAAMAEPAGLAGFASRFPDRMFDVGIAEQHAVTSAAGLAMAGMHPVVAIYST
                     FLNRAVDQLLMDVALHRQPVTFVLDRAGITGPDGPSHHGMWDSSILPVVPGLRLASPRD
                     PARLRELLREAVDVNDGPTVVRYPKATASDDIPAVRRTGHCDVLLECPGADVLLVAVGP
                     LASACLQAADELRAQGVPVIVVDPRWIAPIDPCLLKLAGAHRLVVAVEDTTTPGALGGR
                     IAQALAANGSDTCAATFALPPRFLPHASRSEILRAHGLDAAGITTTVLKRLEALS"
     gene            13739..14836
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="B9C43_RS19380"
                     /old_locus_tag="SAMN05661093_03951"
     CDS             13739..14836
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666919.1"
                     /locus_tag="B9C43_RS19380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03951"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_084428380.1"
                     /transl_table=11
                     /translation="MTLVQLGPPTLRRKSRQVLVGDVPVGGNAPVSVQSMTTTVTSDVD
                     STLQQIAELTAAGCQIIRVAVPSQDDADALPAIARKSPIPVVADIHFQPKYVFAAIEAG
                     CAAVRVNPGNIRQFDDKVREISLAASSAGVPIRIGVNAGSLDKRLLEKYGKATPDALVE
                     SALWECSLFEEHGFRDIKISVKHHDPLVMIEAYRKLAARCDYPLHLGVTEAGPRFQGTI
                     KSSVAFGVLLAEGIGDTIRVSLSAPPVEEVKVGAQILESLGLRPRRLEIVSCPSCGRAQ
                     VDVYKLAEEVTAAFDGFPVPLRVAVMGCVVNGPGEAREADLGVSSGNGKGQIFVRGQVV
                     RTVPESKIVETLLEEALNRDWSTNV"
     gene            14840..15148
                     /locus_tag="B9C43_RS19385"
                     /old_locus_tag="SAMN05661093_03952"
     CDS             14840..15148
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_03952"
                     /product="hypothetical protein"
                     /protein_id="WP_033389426.1"
                     /transl_table=11
                     /translation="MREVQQKVAQVADKLGLHANAPSLTLTLLSEIGRLSDEVLAATAN
                     GRRPFRPTEGWEQRLADLAFTVINLADQTGVDLTTALEGTIARHEANAKPVDDLPGW"
     gene            15190..15570
                     /locus_tag="B9C43_RS56740"
                     /old_locus_tag="SAMN05661093_03953"
     CDS             15190..15570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153994.1"
                     /locus_tag="B9C43_RS56740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03953"
                     /product="VOC family protein"
                     /protein_id="WP_084428381.1"
                     /transl_table=11
                     /translation="MASRIHNVSLNALDAYGLAEFWAKVYDRPIDEVDKPGDPEVAIDL
                     GGGMNMFFQQVPEAKTPLRNRMHICLQPDTTRDEEVDRLQGLGAKLLEDFRRPDGTGWV
                     VMADPEGNEFCVERSTAERAAT"
     gene            15588..16025
                     /locus_tag="B9C43_RS19395"
                     /old_locus_tag="SAMN05661093_03954"
     CDS             15588..16025
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS19395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_03954"
                     /product="hypothetical protein"
                     /protein_id="WP_084428382.1"
                     /transl_table=11
                     /translation="MRNAELEKLGGLVGTWATTLSNAWFLDPPGLEVPGTTTIEWLGES
                     LLFMRTKLGERAHHSEMSFVIGRSDPNNTYVALYQDDRGVCRFYAMTFAGGHWTMSRED
                     PDMHQRFIAEVENDRIVGRWEASEDQGETWRKDYGLTFERT"
     gene            16128..17321
                     /locus_tag="B9C43_RS19400"
                     /old_locus_tag="SAMN05661093_03955"
     CDS             16128..17321
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="B9C43_RS19400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03955"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_143446456.1"
                     /transl_table=11
                     /translation="MHTDVDIAVIGGGRGGLTLAIGLLRRSVSVAVFEQTSELREIGAG
                     VAIAANGTRLLRELGVELANAGNIPPYLEFRRWNDGGLISSHELGRWYEDRMGAPMVTM
                     HRGTLQRMLTEQVPKEHVHLDHQVTELVAEDGGVRLRFANAPDVVAKAVVGVDGMRSVV
                     RRYVAGAVSPVCSGEIGFRGVIPVGASPSLPNPTSLQVWCGPRTHAITYGVDDGRLINL
                     LAVSVPDEIPAWTRSTNRVPATRAEALAIFSRAGWTDSMLELIRGIEGDMHFWALQELP
                     GLRRWSRGRVVLAGDAAHAPLPHQGQGAGQAIESAYTLAHLLAEAGPDAYQRAFDIYER
                     LRKQRTRRVQHYSRMAGKLIKLTGATVPRRDHDLADLPRRIGWIHEYRADFAVRAAQ"
     gene            complement(17349..18071)
                     /locus_tag="B9C43_RS19405"
                     /old_locus_tag="SAMN05661093_03956"
     CDS             complement(17349..18071)
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103396.1"
                     /locus_tag="B9C43_RS19405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03956"
                     /product="MIP/aquaporin family protein"
                     /protein_id="WP_084428384.1"
                     /transl_table=11
                     /translation="MSPRSTEPLARPVLAEFLGSMLLAAVVIGSGIAAQRLSPDDVGLQ
                     LLENAAATAAGLYALILIFGPVSGAHFNPVVTLADVLLGGSSWRRFLAYAPAQVAGCVT
                     GAVVANVLFSADPVSISTTERATFAHGVSEVVATAGLLLVIFSLVRTGRADRAPAAVGA
                     YIGAAYFFTSSTSFANPAISVGRIFSDTFAGIAPSSVPLFVLTQLIGAGVAIGVVSLLY
                     PSTDRQRDQLRADVTTAA"
     gene            complement(18052..18699)
                     /locus_tag="B9C43_RS19410"
                     /old_locus_tag="SAMN05661093_03957"
     CDS             complement(18052..18699)
                     /EC_number="1.20.4.4"
                     /GO_function="GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011331629.1"
                     /locus_tag="B9C43_RS19410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03957"
                     /product="arsenate reductase ArsC"
                     /protein_id="WP_033389418.1"
                     /transl_table=11
                     /translation="MTETHDLSIDQRLALRSAATRLREQFDGVFGQETIELFLHSSYDQ
                     FASRSTIPNFLPLLAERFARQRLQALAKVEGHIQDGKPVVLFLCVHNAGRSQMALGFFQ
                     YLAGDGAVAWSGGSEPGYEINPSAVAAMAERGIDISKEFPKPWTTEIVQAADVVITMGC
                     GDACPVFPGKRYLDWQLDDPAGKGVEDVRPVRDEIERRIRDLLEELNVPALH"
     gene            complement(18692..19375)
                     /locus_tag="B9C43_RS19415"
                     /old_locus_tag="SAMN05661093_03958"
     CDS             complement(18692..19375)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003944613.1"
                     /locus_tag="B9C43_RS19415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03958"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_084428385.1"
                     /transl_table=11
                     /translation="MNVEWPSALVDRARQHAALGEPARLAIVDLLSLGDASPSELGRAL
                     GLPSNLLAHHVKSLEQAGIVERSRSEGDHRRTYLRLRVLHDLSPRGARDASRVVFVCTG
                     NSARSQLAAALWKRRSQVPATSAGTVPARRVHPLAVATARQHGLSLARARTAHVRDVLQ
                     PDDLVVAVCDNAHEELAEGERLHWSVPDPVKAGSDDAFERAFVDLAERVERLAPAVHPL
                     GDKDD"
     gene            19614..20282
                     /locus_tag="B9C43_RS19420"
                     /old_locus_tag="SAMN05661093_03959"
     CDS             19614..20282
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016163.5"
                     /locus_tag="B9C43_RS19420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03959"
                     /product="DUF429 domain-containing protein"
                     /protein_id="WP_160096588.1"
                     /transl_table=11
                     /translation="MGVDACKAGWVGITVAAGQVDSHVAATIEELVALADGPLAVIAID
                     MPIGLPDRDQREADILARQQIGSLRSSVFMTPVRAVLDATDHLTASERNRQLTGEGISI
                     QAFGLLHKLRQVDRWIRQRPCHVVEAHPEVSFALLAGAPLTARKHTWAGAHLRRRLLTD
                     AGIPLDSDLGDAGRKAAVDDVLDAAICAWTAQRVARGQARSLPDPPQVFTDGLPCAIWS
                     "
ORIGIN
        1 cagtggcgat tcgaatggca gcggcagtac acccgggacg agtggctgga tcgcgtgccc
       61 accaacggcg gcatgaacct gctcccaccg gacaagctcg ccgaagtgct gacggacctg
      121 gggcaggcaa tcgacgccat cggcggcagc ttcacgatga gctacacgac catcgcggtc
      181 acggcgatac ggatctgaac cgcgcctcgg cctgttccgc ggtcagcccg aagtcggcca
      241 ggtcatagcg gtgcgatcgg cgccggtcgc ccgaagtgtg cacggctttc atcgcgtcga
      301 ggacgtcatc tgaaatgtcc atgccgaaat gggtgtagat atcggtgacc acgctcagtg
      361 gatcggccac gaagtcgtcg tactgcacgt cgtagaactg ggcgggattg tgtttcgcgc
      421 ggtcggcgtt gaatttctcc aggccgcgcg cccacaactc gagctgggtc tcgccgatca
      481 ccgagccgtg gaaaaccgtg gaccactcgc ccgatgcttg ttcggcgagg ctgcacatcg
      541 acgcgatgat cgtgctcggc gcccggtggg tttggatgat caacgcgtcc ggataggcgt
      601 caagcagggc atcgagtgcg aacaggtggc tggggttctt caacacccag cgtttcgagg
      661 cgtccggcat gccgatcagc tggaggttac gccggtgccg gtgatacgcc tcggtccagt
      721 cctgttccgc cagccacgcg gaatacgttg gcacgtaagc aagacactcg aacgatatgg
      781 acatcatcga ctgccgcagc agccgccagc attcctcggc catgtccgcc gtgatgtagt
      841 gcaggcccat gaactccggg tgctcgacgt ggtgctgctc gtacccggcc tggatccgtt
      901 ggtacatcgg gttttcgtcc cacgtctcgc gcggggggcg tggctgcggc acgtcggtga
      961 gccacaactc cagcccttgg tgggcggggt cctcggtgag cagccggtgc aacgcggtcg
     1021 tcccggtccg gggcagcccg gtcacgaaga ttggccgctc aatcggcaca gacgcgtagt
     1081 caggaagacg ttgccacgca gcctcactga gcagccgcgc caccagagct gagcgcagcc
     1141 cggcccgttt cacccgtaac cccaactcgg tcagaccggc ttcgcggtgg tacgagtcca
     1201 gcagcaccga gaggccttcg aggtagccgg agtccccgaa gtcggtcagt ccggtgatct
     1261 tcgtcgccga cgcgtgcaga gactcgatgt ccacagttga ctcctagtgg tggtactcgc
     1321 cgccgttcac gtcaaggcac tggccggtga ccgcgctggc caaagacgaa gccaggaaca
     1381 cgatggtgtc cgcgacctcg tcgggctccg gcagtttgcg caggtcgatg ttggccgcca
     1441 cctcgtcgta gacctcttgt ggcgtgatgc cgcgttgctt ggccaggtag tcgaagtaga
     1501 acttcacgtt gtccgcccag atgtaaccgg gcgcgatcgt gttgacccgc acgcccttgg
     1561 ggcccagctc cgtggaaagg ctctgcgcca tcgccagcaa ggcggacttg gtcatcttgt
     1621 acggccccat cgtcagctgc gagtgccgga tcaccatcga gctgaccatc acgatggagc
     1681 cgcggctggc ctccagcgcc ggacggaaca ggttcaccag ccgcaacgcg ccgagcacgt
     1741 tggtctcgaa gccgtcgcgg atcccttcga acggggcacg gtcgaaagtg gtcatcggcg
     1801 gcatggcgaa ggcgttgttc accaacgtgt ccacccggcc gaaggactcc agtgcggtct
     1861 cggccaggcg agccgcgtcg tcctcggacg agatgtccgt cgtcacggtc accgcacgcc
     1921 ggccgagatc ggtgacctcc ttggccactt cggtcaaccg ggactcggtg cgcgccgcca
     1981 gcacgatgtc cgcaccttgc cgggcgcacc gcaacgcgat cgaccggccg agtcccggcc
     2041 cgatcccgga gaccacgacg accttgtcct gcaacaacat cagcccacca tcctggtcgc
     2101 tacggccgcc tgacgcgcgg caatccggtc cttgtactca gctggggtga tgcgtgcgtc
     2161 ttcgtggaac gggagtttcc gggcgagttc actgaccgga acgacttcca cggcaggtcc
     2221 gtccgagggt ttgaggtcac gcgacagccg ctgccaccgg atctgcagat atcccttggc
     2281 atggccggtg cgttcgatcc agttcaccag ccccggatcg cgttcgctga ccacgtacct
     2341 gatcttgccg tccgggtcga tccgggcctg gtccgcggtc aggctggtct ggtggttgat
     2401 gtagtccagc gagatgtacc acatgctgcc gagctgaaat ccctggtacg gcgcctcgga
     2461 cgcgggcacc gtgatgatca tcgcctcttc gtcggcgagg tcgtagtgcc cgaccgagga
     2521 gaactgggtg gccagtccgc caggcgtcag ccgcggctcg gtcatcgtgt tcaccggcag
     2581 cttcaagtag aaccacttcg ggaacgccag gaacgtcttg atccgtccga tgaggatctt
     2641 gcctgccacg gtgtaccgct tggccatcaa gtccttcgtc ggagcaggcg gtgccgaacc
     2701 ggtggtgtcc gtgcggcgga tcttgatcat cccgcgttct tcgccggtcc agtcgctgta
     2761 gacctcacgc acgatcagca tcgccgagcc gtcgccgagg gtgaagtagt tgcgcccggc
     2821 tttgcccggc ccgaagcgga tctcgaacga gccgtcctcg gcgatgtcga actcgcggtc
     2881 gtcgaacgcg gtcaggctgt ccggcacgtc caccggcgag tagtcaccgt tgagcacctg
     2941 gaagctcagg tcagcggtgc tgccgcgctt gccggtcacg acgtactcgg cgtcctcgcg
     3001 gatgtaggcg tggaagtaca gcgtgtccgg gttgtccagg cccatcttgg tgtacggccc
     3061 ggtggactgg acgaagtacg ggaagtcacg gtcgtacgcc cacgccatct gcaacgaggc
     3121 ccggatgctg cctgccaggt agtcgtagcc ctcggtcagg tcctgatcgg tctggacatg
     3181 cggcgcctgc gtgatcagct tctcggcttc ggcgaccgcg gcggcgaatg actcggtgag
     3241 caccgaccta ggctagaacg tgttctaaca tccggtcaaa caccggccag gaacttcagg
     3301 ctcggcagat cgtcccagga caccatcgcc tcgtagagcc ggttgtaggc gatgtgcttg
     3361 atccgccagc cgtgctcggg cgaccggacg tactgctctt cgtagtaggc ggcgcccttg
     3421 atcacgaggc ggtgctcctt gacgatcacg gtgtcctcga acgcccaggt cccggtggcc
     3481 gagtcgccgt cgacgtcgat ctccggctgg ccggcgaagt ggaacgtgat gatcttgtcg
     3541 ccgccgaggt tctgccgcat gaagtccagg atcgcggccc gtccggtgag cacgagcggc
     3601 tctcccatcg ccttggtccc gtagtcggcg accgcgtcct cggtcagcgc gtcctccagc
     3661 aagtcccagc gtttctggtc gacgccgcgc agatatcggt acttcagccg gcggatctct
     3721 tcgatcacat gcaagtcgtc catgccgacc agctaacccc tgagcattga ccagtgcaat
     3781 aacctgttct agtttttgat cgtggccacc acgtacgagc tgtccaatct gcgcgcgctc
     3841 gaggccgagt cggcgcacgt gctgcgcgag gtcgcggcga cgttcgagcg cccggtgctg
     3901 ctgttctccg gcggcaagga ctcggtggtg atgctgcacc ttgcggccaa ggcgttctgg
     3961 cccgcgccac cgccctttcc ggtgatgcac gtggacaccg ggcacaactt cgacgaggtc
     4021 atcgagttcc gggaccgcac agtcgaatcg acgggcgtcc ggctcgtggt cagccacgtc
     4081 caggacgaca tcgacgcggg ccgcgtcgtc gaagagaccg ggcctagagc gagccggaac
     4141 cgcttgcaga ccacggcttt gctccgagcc atcaacgaaa accggttcga cgcggtgttc
     4201 ggcggagccc gccgggacga agagaaggca cgggccaagg agcgcgtgtt cagcttccgt
     4261 gacgagttcg gccaatggga tccccgcaac cagcgacccg agctttggaa cctctacaac
     4321 ggacggcatc gccgcggcga acacatccgg gtgttcccgt tgtccaactg gaccgaattg
     4381 gacatctggc agtacatccg ggacgaacgc atcgagctcc cggagatcta ctacgcacat
     4441 cggcgacaag tgttccaacg cgacggcatg ctcctggcgc ataccaggtt cgtgacgctc
     4501 ctgccgggcg aagaaccctt tgaggcgtcc gtgcggttcc gcacagtcgg cgacgcgacc
     4561 tgcaccggct gcgtcgaatc cactgccgcc acaccggaag aggtcgtcgc cgaagtcgcc
     4621 gcgacccgcg tgaccgagcg cggcgcgacc cgggcggacg accggatctc cgaggcaggc
     4681 atggaggacc gcaagaagga gggctacttc tgatgaacca gcttctccgt cttgccaccg
     4741 cgggcagcgt cgacgacggc aagtccactt tgatcggcag gctgctgttc gactccaaga
     4801 ccatcttcga ggatcagctc gcggcgatcg aacgcagcag ccgcgaccgc ggcgaggact
     4861 acccgaacct ggcgctgctg accgacgggc tgcgcgcgga gcgggaacaa ggcatcacga
     4921 tcgatgtggc gtaccgctat ttcgccacac ccaaacggaa attcatcatc gcggacacgc
     4981 ctgggcacat ccagtacacc cgcaacatgg tcaccggggc gtccacagcg gacctcgcac
     5041 tgatccttgt ggacgcccgc aaagggattc tggagcagtc acgcaggcac gcgttcctgg
     5101 ccagcctgct gggcatcccc cacctcgtcg tgtgcgtgaa caagatggac ctggtcggct
     5161 ggtcccggga acgcttcgaa gagatccgtg aggagttccg ccagttctcc atgaagctga
     5221 ccgtgcccga cctgacgttc gtaccggtgt cggcactcca cggcgacaac atcgttcacc
     5281 gcagtgcatc gatgccttgg tacgaaggca cttccctgct gcaccacctc gaagaagtac
     5341 acatcagctc ggaccgcaac ctgatcgacg cccggttccc ggtgcagtac gtcatccgcc
     5401 acaaggactt ccgtggttac gccggaacgg tcgccggcgg tgtgttcaag ccgggcgacg
     5461 aggtactcgt gctgccgtcc ggattcacca cgaccgtgca ggcgatctgg ggcctcggtg
     5521 ggcaaccggt cgccgaggcc tttccaccgc agtcggtcac gctggagctg gccgacgagc
     5581 tggacgtcgg ccgcggtgac ctgatctgcc gcccgaacaa ccggccgcac gtcggccagg
     5641 acgtcgacgc gatcgtttgc tggctgaccg aacgcactga cctgaccccg gacgcgaggt
     5701 acacggtcgt caacaccacc cggtcgacca aggccgtggt caagtcgctg gactaccggc
     5761 tggacatcac cacactgcac cgcgacgaca cagcagagtc cttgtcgctc aacgagatcg
     5821 gccgggtcaa gctgcgcacc cagcaaccgc tgctgttcga cgcgtatcgc cgcaaccggg
     5881 cctgcggcag tttcatcctg gtcgacgaga cgtccaacaa cacggtcgcg gccggaatga
     5941 tcaccgggcc gagccaggcg gtggtctggc attccaccgc ggtccagcgc accgaacgcg
     6001 gctccgtggg ctgcaccgtg tggctgaccg ggctgtcggc gtccgggaag tcgaccgtag
     6061 ccgtggagct ggagcgacgg cttgtggctt cgggacgccc ggcttacctt ctggacggcg
     6121 acaacctgcg ccacggcctg aacgccgacc tcgggttcgg tgcggccgac cgcgcggaga
     6181 acgtccgcag ggccggcgaa gtggcgaagc tgttcgccga cgcgggcgtg gtcgcggtgg
     6241 tctcgctgat cagcccgtat caggctgatc gggaccgggt cagggccatg cacgagcaag
     6301 cgggcttgcc ttttgtggaa gtctttgtgg acactcctgt cgaggtgtgc gaggcccgcg
     6361 atcccaaggg gatgtacgcc aaggccaggg cgggcgagat caccgggttc accggggtgg
     6421 acgacccgta cgaggtacca gtggcacccg aactggtact gcgaccggag caaggcgatc
     6481 ccgcgaggat ggccgcattg atcctcgcct caatggatca ggtcacactg acccggatgg
     6541 actagcggcg gcccgtcgca tcgcccgctg cctacacacg ttcgtcgcag cgtcttgcta
     6601 ctcgcgagtg aacggtgttt cgcaccgaag cactttcggt tcatttattg gcgtgtcagc
     6661 cgcaaaaagc gtgaatcgtc ccatgattgt tttccacagg tcgggcaagc cttttgggtg
     6721 actgcgcacg ttcaaaacgt ggtgctagcc tccgtcttgg caccgtccga actggatcat
     6781 tcagctggga cacgaaaggg tgttccacct ttgtctcaag ccaattcccc atgtctattt
     6841 cccatgaacc cgactaggaa gaatggcggc acgttgtgac cgacacggtg gagtcgaatc
     6901 ttggcgtaga gaacggccag caacagcaga gcctggccac cgcggccgcg cggaatttgg
     6961 cgacgaccac caaatccgtc ccgcagatgc agagcatcac ctcgcgctgg ctgctgcggg
     7021 tcctgccgtg ggtgcaggcc caaggtggcg tgtaccgggt caaccgaagg ctgagctaca
     7081 ccgtcggtga cggccggatc gccgtctcca acaccgggtc cagggtccag gttgtcggcc
     7141 cggacctggt ggaaatggct ctgctgcgca ctttcgagga cgaggacgcg ctcaacgcct
     7201 tggcaggccg gttcgagcag caggagtacg agcccggcgc cgtgatcgcc gaattcggtc
     7261 acgaggccga ctacgtctac gtggtcgcgc acggcaaggt gaacaagatc ggcaccggtg
     7321 agtacggtga ccaaaccgtg ctcggcacga tggtcgacgg cgactatttc ggcgaccagg
     7381 cgctcatcca agatcaaagc atctgggagt tcaccgccaa ggctgtcacc ccgacgacga
     7441 ttctcgcatt gccgaaacag gcatttcagg aattgcaaga tcaatccgag gcgttgcgcg
     7501 agcacgtcaa cgcttaccgc aacagcccga aaaaaccggc aaacccgtac ggtgaagccg
     7561 agatcgaact ggcatccggc cacgacggtg aaccggacct gccgagcacg ttcgtggact
     7621 acgaactctc gccgcgggaa tacgagttga gcgtcgcgca aacagtcctg cgcgtgcaca
     7681 ccagggtcgc cgacctgtac aaccagccga tgaaccagac ggagcaacag ctccggctga
     7741 ccatcgaggc gctgcgcgaa cgccaggaac acgagctgat caacaaccgc gacttcggcc
     7801 tgctctgcaa cgccgacctc aaacagcgca tcccgacccg cagcggcccg ccgaccccgg
     7861 acgacatgga cgaactgctg gcgacggtgt ggaaggaccc gatgttcatc ctggcccacc
     7921 cgcgcgcgat cgccgcgttc ggccaggagt gcaacaagcg gggcctctac ccgcagagca
     7981 tcgacctcaa cggccaccag gttccgtcgt ggcgtggcat ccccgtgttg ccgtgcaaca
     8041 agattccggt gtccaacacg aggaccacgc agatgatcgc gatgcgggtc ggtgagcaga
     8101 accagggtgt gatcggcctg caccagaccg gcctgccgga cgagtaccag cccggcctgt
     8161 cggtgcggtt catgaacatc aacgagaagg cgatcatctc ctacctggtc agcgcctact
     8221 actcggcggc ggtcctggtg ccggacgccc tcggtgtgct ggagaacgta gaactgggca
     8281 gaactgacta gtggccgatc ggcctgagcc gatcgcagcc gtcagtcccc cacctatccc
     8341 ctcggccacc agaccttggc cgttgccacg cctgactttc ccgttcggcc gtcggcgctc
     8401 ccagcggacg gggaagaaca gagaacaaag aacaaagggc gtggtgccct catcggccag
     8461 gggcgagtca aggtggtcga gcgggcgctg gccgatgtgc ggccctccct gaagaagggc
     8521 catcgacatg gttcggcatc ggccagcgtc gaatccccgg cagatccgca ctctcatctg
     8581 atcaactagg aacaggcggt cgaacacgtg acacaggtcg agaaccccca gtcgcagcag
     8641 atgagcctcg gcaccgccgc ggcgcgaaat ctggcgacga cgaccaagtc cgtaccgcag
     8701 atgcagggga tcacgccgcg gtggttgttg cgcgtcctgc catgggtaca ggccgaaggc
     8761 ggcacgtacc gcgtgaaccg gcggctcacg tacgccatcg gcgacgggtt ggtcagcttc
     8821 accagcagtg cgggccgtgt ccaggtggtg ccgccggaac tgcgtgaact ggctctgctg
     8881 cacgatctgg acgacgacga gacgctggcc gcactggccg gccggttcga gcagcaggag
     8941 ttcgaaccgg gagacctgat catccagaga ggaggtcacg ccgaccggct cgtgctgatg
     9001 gcacacggca aggcggacaa gatcggccaa ggtgagtacg gcgcggacac cgtgctcgac
     9061 acgatcggtg aaggcgagta cttcggcgag caggcgctga ccggcctgcg cgacgagtgg
     9121 agcttctcga tcaaggcgaa gaccccgtgc atcacgttgt cgttgtcccg tcaggacttc
     9181 gaccggatca ccgagcagtc cgacaagctg cgggcgcacc tggagtactt cgtctcgttg
     9241 cgcggcaagc ggagcaacgc caagggcgag gcagagatcg agctgtcctc cggccacgaa
     9301 ggcgaagcgc tgctaccggc cacctttgtg gactacgaac tctcgccgcg tgagtacgag
     9361 ctgagcgtca cgcagacggt cctgcggatc cacaccaggg tcgcggatct gtacaaccag
     9421 ccgatgaacc agaccgagca acagctccgg ctgaccgtcg aggcgctgcg tgaacgccaa
     9481 gagtacgaga tgatcaacaa ccggcagatc gggctgctgc acaacgcgga cctcaagcag
     9541 cgcatcccca cccggaccgg gccgccgacc ccggacgaca tggacgagct gatctcacgc
     9601 aggcgcaaga cccagttcat cctcgcccac ccgaaggcga tcgccgcgtt cggccgggag
     9661 tgcaacagca gggggatcta cccgaacacc aaggaactcg acggcaagat cgtccgcacc
     9721 tggcgcaaca tcccgctgct gccgtgcgac aagatcccgg tcagcgagac cggccggacc
     9781 tcgatcatcg cgatgcggac cggcgagaag aaccagggcg tgatcggcct gcaccacgcc
     9841 ggcctgccgg acgagctcga acccggcctg aacgtgcggt tcatgggcgt caacgagaaa
     9901 gccatcatgt cgtacctggt cagtgcctac tactcggtcg cggtgatggt gccggacgcg
     9961 ctcggcatcc tcgagagcgt tgagctcggg cgttgatgtc atgacacttc gtgaggtgac
    10021 gaccgaaagc cgtcaaccgg gtgaggtgct ggcatggagc agggacatgg tcgacccggc
    10081 gacccgtgcc gcggtcggca ccctgcccgg ttcgatgcgg catatcgccg gttaccacta
    10141 cgggtggtgg gacgagaccg gcacgccgac ggaaacctct ggcggcaagg cattacggcc
    10201 gacgttgacg ctgctggcgg ccgaggcggt cggcggtgtg gcgtcggccg ccgtgcctgc
    10261 cgccgtcgcg atcgagctgg tgcacaactt ctccttgctg cacgacgacg tgatcgacgg
    10321 tgacgtcacg cgcaggcacc ggccgacggc gtggagtgtt ttcggccgca gtgcggcgat
    10381 tctggccggt gattccctgc tgacgctcgc cttcgacgtc ctcgcggcga gcgggcatcc
    10441 cgattcccgg gagggcatgc ggatcctcag cgccgccgtc cagtcccttg tggagggcca
    10501 gagtctcgat gtggcgttcg aggaccgcca ggacatcgaa ctggccgagt gcgaggtgat
    10561 ggctcggggc aagaccgggg cgctgatcag cgcggcgtgt gccatcggag cgttgttcgg
    10621 cggcgcccgc agcgcgcagg tcgagcacat gcgtgccttc ggcgcggaac tcggcctggc
    10681 gttccagttg gtcgacgacc tgctcgggat ctggggtgac ccggcggtga ccggcaagcc
    10741 ggtgtactcg gatctgcaca accgcaagaa atcgctgcct gtagtggccg cgttgagatc
    10801 gaaaactact gcggcacagg aactacacga gctgtaccac gccgaccggc cgttgtcggg
    10861 cgttgacgtc gaacgcgccg ccgcgctgat cgacgcggcc ggtggccagg cgtggtgcca
    10921 ggcacaggcc gacgaccggc tggcccgtgc tatccaccgg ctgcggtcgg cggacccagt
    10981 ggccggtgcc gccgccgaac tggccgggct ggcctgcctg gtcacccatc gcgaccactg
    11041 agttccctcg tggggtttct aaccggactg gagactcacg agcagataag aggggccgcc
    11101 atgcaggtca aggtgttgct cgcgtcgcca cggtcgttct gcgccggggt ggaacgcgcg
    11161 atcgagatcg tcgaagaggt gctgcggcac cgaaaaccac ctgtctacgt gcgtaagcag
    11221 atcgtgcaca acaagcatgt cgtcgccgat ctggccacac gcggtgcggt gttcgtcgac
    11281 gaactcgacg ccgttccgga cggcgcgacc gtggtcttct cggcacacgg ggtctccccc
    11341 gccgtgcgtg aggaagccga acggcgacgg cttgacgtga tcgacgcgac ctgtccgctg
    11401 gtcacgaagg tacacacaga ggcccgtcgc ttcgccggcc gaggcgacac ggtggtgcta
    11461 gtcggacacg ccgggcacga ggaggtggaa ggcacgctcg gcgaggcacc agaccggacc
    11521 gtactggtgc agaccgcgga agatgttgcg agcctggaca ttcccgatcc gtcgagggtc
    11581 tcgtacctga tgcagacgac gttggcggtc gacgaggccg cggaggtggt gtcggccctc
    11641 cgggctcggt ttccggacct gcgcggcccg gcttcggacg acatttgtta cgccacaacc
    11701 aatcggcaga acgcgttgca cgcgatcgcc gacgaggcgg acctggtcct ggtagtcggg
    11761 tcgacgaatt cgtccaactc ggtgcgactg gtcgaattgg cgcaacgcca tggcacgcct
    11821 gcgtacttga tcgacgatgt cagcgacatc aaggcgagat ggctggaggg tgtgcgtgtc
    11881 atcgggatca ccgcaggcgc ttccgcacca ccgggactgg tcgacgaggt ggtcgccgcg
    11941 ttgaacccga tcagcgtgga gaaccgggaa acggtcaccg agaccatcca gttcaccctg
    12001 ccgcccgcgg cgaggcggtc gtcatgatct cgggtcccgc cgatctggcg gccaagtcca
    12061 cttccgaact ggccactgtg gccaatgaca tccgtgactt cctgattcgc aaggtgtcca
    12121 ggaccggcgg gcacctcggt cccaacctcg gcgcggtcga gctgaccatc gccctgcacc
    12181 gggttttcca ttcgccgcac gacgtcctgc tgttcgacac cgggcatcag gcctacgtgc
    12241 acaagatcct gaccggccgc gagtccgatt tcgactcgct gcgccaagcc ggtggcctgt
    12301 ccgggtatcc gtcccggtcc gagtccgaac acgacgtgat cgagaactcg cacgcgtcca
    12361 ccgcgctgtc ctatgcggac ggatgggcca aggccttcgc gttgcagcaa tcgacgcgcc
    12421 gagtggtcgc ggtgatcggc gacggcgcgt tgaccggcgg gatggcgtgg gaggcgttga
    12481 acaacatcgg ctccgcgccg gaccgtccag ttgtcatcgt gttgaacgac aacggacggt
    12541 cgtacgcgcc tactatcggc gggatagcta gtcatctagc cgtgctgcgc tacgagggcg
    12601 accgcaacat cttcgaggac ttggggttgg cgtacatcgg cccggtggac gggcacgaca
    12661 tcaccgacct ggagcacgct ttgcgcaagg cagtccggtt gaacagaccg gtggtggtgc
    12721 attgcctgac gcgtaaggga aaagggtacg caccggccga agaggacgaa gcagaccgcc
    12781 tgcacgcggt cggacccgtt ggtgcggcca agaaacgatc gtggacctcg gtgttcgccg
    12841 aggagatcac ggcgatcggc gcggagcgcg aggacatcgt gtgcatcacc gcggccatgg
    12901 ccgaaccggc cggcttggcc ggcttcgctt cgcgtttccc tgaccggatg ttcgacgtcg
    12961 ggatcgccga gcagcacgcc gtgacctcgg ccgcgggcct ggccatggcc gggatgcacc
    13021 cggtggtggc gatctactcg acgttcctga accgcgcggt cgaccagttg ctgatggacg
    13081 tggcactgca ccggcaaccg gtcacgttcg tgctcgaccg agccgggatc accgggccgg
    13141 acgggccgag ccaccacggt atgtgggact cgtcgattct gcctgtcgtt cctggtctcc
    13201 ggcttgccag cccacgggac ccagcgaggc tgcgggaact gctcagagaa gcggtcgacg
    13261 tcaacgacgg accgaccgtc gtgcgctacc ccaaggccac cgcgagcgac gacatcccgg
    13321 ctgtgcgccg gaccgggcac tgtgacgtgc tgctggaatg cccaggtgcc gatgtcttgt
    13381 tggtcgcggt tggcccgttg gcgtcggctt gtcttcaggc cgcggatgaa ctgcgtgccc
    13441 agggcgtgcc ggtgatcgtg gtcgatcccc gctggatcgc gccgatcgac ccgtgcctgc
    13501 tgaagctcgc cggggcacac cggcttgtgg tcgcggtcga agacaccacg acaccaggag
    13561 ctttgggcgg acggatcgcg caagcgctgg cggccaacgg ttcggacacg tgcgcggcga
    13621 ccttcgcgct gccgccacgg ttcctgccac acgcatcccg ctcggagatc ctgcgcgcgc
    13681 acggcctcga cgcggccgga atcaccacca ccgtgctcaa acgcctggag gcactgtctt
    13741 gaccctcgtt caactcggcc cgccgacgct gcgccggaag tcccgtcaag tgctcgtcgg
    13801 cgacgttccg gtgggcggga acgcgccagt gagcgtgcag tcgatgacga cgaccgtgac
    13861 gtccgatgtg gactcgacgt tgcagcagat cgcggagttg accgcggcgg gctgccagat
    13921 catccgggtg gccgtgccct cacaggatga cgccgacgca ctgccggcga tcgctcgcaa
    13981 gtcgccgatc ccggtggtcg cggacatcca cttccagccg aagtacgtgt tcgccgcgat
    14041 cgaggcgggg tgtgccgccg tgcgggtcaa tcccggcaac atcaggcagt tcgacgacaa
    14101 ggtgcgggag atttcccttg ctgcctcgtc cgccggtgtc ccgatccgga tcggggtcaa
    14161 cgcggggtcg ttggacaaac gtttgcttga gaagtacggc aaggccacgc cggacgcgtt
    14221 ggtcgagtcc gcgctgtggg agtgttcgtt gttcgaagaa cacgggttcc gggacatcaa
    14281 gatctcggtg aagcaccacg atccgctggt gatgatcgag gcgtaccgca aactggccgc
    14341 gcgctgcgac tacccgctgc acctcggggt gaccgaagcc gggccacgct tccagggcac
    14401 gatcaagtcg tcggtggcct tcggtgtgct gctcgccgaa gggataggcg acaccatccg
    14461 ggtctcgttg tccgcgccac cggtcgagga agtcaaggtg ggcgcgcaga tcctggagtc
    14521 cttggggctc cggccgcgca ggctggagat cgtctcgtgc ccgtcgtgcg ggcgggccca
    14581 ggtggacgtc tacaagctgg ccgaggaggt cacggccgcg ttcgacggtt tcccggtgcc
    14641 gctacgggtg gccgtgatgg gctgcgtggt gaacggaccg ggcgaggcgc gcgaagccga
    14701 cctcggcgtg tcgtccggaa acgggaaggg acagattttc gttcggggac aagtggttcg
    14761 gaccgtgccg gagagcaaga tcgtggaaac cctgctcgag gaggcgctga atcgcgattg
    14821 gagcactaat gtctgagccg tgcgagaagt ccagcagaag gtcgcccagg tcgctgacaa
    14881 actcggcctg cacgcgaacg cgcccagcct gacactgaca ctgctgtcgg aaatcgggcg
    14941 gttgtccgat gaagtgcttg ccgcgaccgc gaacgggcgc aggccgttcc ggccgacgga
    15001 aggctgggag cagcggctgg cggacctggc gttcacggtg atcaacctgg ccgatcagac
    15061 cggcgtggac ctgaccacgg cattggaagg cacgatcgca cggcacgaag cgaacgcgaa
    15121 acccgtcgac gacctgcctg gctggtaatt cgctttgcgg cgtgcgcggg cctgcagttg
    15181 gatgacgtga tggcatccag gatccacaac gtgtcactga acgcgctgga cgcgtacggc
    15241 ctcgccgagt tctgggccaa ggtctacgac aggccgatcg acgaggtcga caaaccgggt
    15301 gaccccgaag tggcgatcga cctcggcggc gggatgaaca tgttcttcca gcaggtgccg
    15361 gaagccaaga cgccgctgcg caatcgaatg cacatctgcc tgcagcccga cacgacccgg
    15421 gacgaggaag tagaccggct gcaaggactc ggcgccaagc tgctggaaga cttccgtcgc
    15481 ccggacggca ccggctgggt cgtgatggcg gatcccgagg gcaacgagtt ctgcgtcgag
    15541 cgcagcacgg cggagcgcgc agccacctga accactcgga ggaaccgatg cgcaacgcag
    15601 aactcgagaa gctcggcggc ctcgtcggca cgtgggcaac gacgttgtcg aacgcctggt
    15661 tcctcgaccc gccgggcctc gaagtgccag gaacaaccac catcgagtgg ctcggcgagt
    15721 cgctgctgtt catgcgaacg aaactcggcg aacgcgcgca ccactccgag atgagcttcg
    15781 tcatcggacg cagcgacccg aacaacacat acgtcgcgct ctaccaagac gatcgcggcg
    15841 tatgccgctt ctacgccatg accttcgccg gtgggcactg gaccatgtcc cgtgaagacc
    15901 cggacatgca ccaacgcttc atcgccgagg tcgaaaacga ccggatcgtc ggccggtggg
    15961 aggcctccga ggaccagggc gagacgtggc ggaaggacta cggcctcacg ttcgagcgga
    16021 cttaggactg ggcggcgcgt tctctagtgc aacgcagcga ggtagctgac ttgtcttgcc
    16081 gtcctgggct gcgttgacga gtaggctccg gggcgggggt gcgtgacatg cacacagatg
    16141 tggatatcgc ggtcatcggg ggcgggcggg gtgggttgac cctggcgatc ggtctgctgc
    16201 gccggtctgt ttcggtggcg gtgttcgagc agacctccga attgcgcgag atcggggctg
    16261 gcgtcgcgat cgcggccaac ggaacccggc tgttgcggga actgggtgtt gagctggcaa
    16321 acgccgggaa cattccccct tacctggaat tccgccgctg gaacgacggc ggcttgatct
    16381 cctcgcacga gttgggacgc tggtatgagg accgcatggg ggcgccgatg gtcaccatgc
    16441 atcggggcac gctgcagcga atgctcaccg agcaggtgcc gaaggagcac gtccacctgg
    16501 accaccaagt gaccgaactc gtcgcggaag acggtggggt acgcctgcgg ttcgccaacg
    16561 cgccggatgt ggtggccaag gccgtggtcg gcgtcgacgg catgcgttcg gtggtccgcc
    16621 gctacgttgc tggggcggtg tcaccggtct gttccggtga gatcgggttc cgtggagtga
    16681 tcccggtagg cgcgtcaccg agtctgccca acccgacgtc gctacaggtg tggtgcggtc
    16741 ccagaaccca tgccatcacc tatggcgtgg acgacgggcg gctgatcaac ctgctggccg
    16801 tgtctgtacc cgacgagatc ccggcatgga cacgatcaac caaccgtgtg cctgccactc
    16861 gcgctgaagc gctcgcgatc ttctcccgtg ccggatggac agacagcatg ctcgaactca
    16921 tccgcggtat cgagggtgac atgcatttct gggcgttgca ggagttgcca ggcctgcgcc
    16981 gatggagccg tggccgcgtg gtactggccg gcgatgccgc gcatgcaccg ctgccgcacc
    17041 agggccaggg agcaggccaa gccatcgaaa gtgcctacac cttggcccac ttgctggccg
    17101 aagccgggcc ggacgcctac cagcgcgcgt tcgacatcta cgagcggctg cgcaaacaac
    17161 gcacgcgacg ggtgcagcat tactcgcgga tggccggcaa gctgatcaaa ctcaccggcg
    17221 caaccgtgcc gcgacgcgac cacgacctgg cggacttgcc gagacgaatc ggctggatcc
    17281 acgaataccg cgccgacttc gccgtccgcg cagcccaatg acattcgatc gccggccccg
    17341 cgacaacctc aggcggctgt tgtgacgtcg gcccgcagct ggtcacgctg gcgatcggtt
    17401 gacggataaa gcaagctcac cacgccgatc gccactccgg ctccgatcaa ctgagtgagg
    17461 acgaagagcg ggaccgaaga gggggcgatg ccggcgaagg tgtcgctgaa gatccggccg
    17521 acgctgatag cggggttggc gaagctcgtc gaactggtga agaagtacgc cgcgccgatg
    17581 tacgcaccca ctgcggcggg tgcccgatcg gcgcggccgg tgcggacgag cgagaagatc
    17641 accagcagca ggccagcggt cgcgacgacc tcggagacgc cgtgggcgaa ggtcgcccgt
    17701 tcagtcgtgc tgatgctgac cgggtcggcg gagaacagca cgttggccac gaccgcaccc
    17761 gtgacgcaac cggccacttg cgccggggcg taggccagga atcggcgcca ggacgaaccg
    17821 cccagcagga catcggccag cgtcaccact gggttgaagt gtgcgccgct gaccggcccg
    17881 aagatcagga tcaacgcgta cagcccagcc gcagtcgcgg cggcgttctc cagcaactgc
    17941 aacccgacgt cgtccgggga caggcgttgc gcggcgatcc ctgagccgat cacgaccgcg
    18001 gcgagcaaca tgctgcccag gaactcggcg aggaccgggc gtgcgagcgg ctcagtggag
    18061 cgcggggaca ttcaactcct caagcaggtc acggatacgg cgttcgatct cgtcacgcac
    18121 cgggcgaacg tcctcaacac ccttgcctgc cgggtcgtcg agctgccagt cgaggtagcg
    18181 cttgcccggg aacaccgggc atgcgtcgcc gcagcccatc gtgatcacca cgtcggcggc
    18241 ctggacgatc tccgtggtcc acggcttcgg gaactccttg gagatgtcga tcccgcgttc
    18301 ggccatggcc gcgaccgcgg acgggttgat ctcgtaacca ggctccgaac cgccggacca
    18361 cgcaaccgcg ccgtctccgg ccaggtactg gaagaacccg agtgccatct ggctacgccc
    18421 ggcgttgtgc acgcacagga acagcacgac cggcttgccg tcctggatat gtccttccac
    18481 tttggccagt gcttgcaggc gttgccgggc gaaccgttcg gccagcaagg gcaggaagtt
    18541 cgggatcgtg ctgcgcgagg cgaactggtc gtagctggag tgcaggaaca gttcgatggt
    18601 ttcctggccg aacacgccgt cgaattgctc gcgcaagcgg gttgccgcgg agcgcagggc
    18661 aaggcgttgg tcgatgctca ggtcgtgggt ctcagtcatc cttgtctccc aagggatgta
    18721 ccgcgggcgc gagccgctcg acgcgctcgg ccaagtcaac gaaagcgcgt tcgaaagcgt
    18781 cgtcgctgcc tgccttgacc ggatcgggga ccgaccagtg cagtcgttcc ccctcggcga
    18841 gttcttcgtg cgcgttgtcg cacacagcaa ccaccaggtc gtcaggctgg agtacgtctc
    18901 ggacatgcgc tgtgcgagca cgggccagcg acaacccatg ctgccgcgca gtggccacgg
    18961 caagcggatg cacgcgcctg gccgggaccg tccccgctga cgtggcgggg acctgactac
    19021 gtcgtttcca caacgcggcc gcgagttgcg aacgcgcgga atttcccgtg cacacgaaga
    19081 ccactcgtga cgcgtcccgg gcgcccctcg gggacaggtc gtgcagcaca cgcaaccgga
    19141 ggtaggtccg gcgatggtca ccttcggacc gggatcgctc cacgattccg gcttgttcca
    19201 acgacttcac atgatgggcc agcagattgc tcggcaagcc caatgcccgc cccagctcgc
    19261 tgggcgacgc gtcgcccagc gacagcaggt ccacgatcgc caaccgagcc ggttcgccga
    19321 gcgcggcgtg ctgccgcgcc cggtcgacca gcgccgaagg ccactcaacg ttcattgagt
    19381 caatgattgc tgagttaatc gcccgagtca acccggccat tgctgtcctg cacatgaacc
    19441 tgaccgtcgg ctagccgctg accttgcagt tgcgttcgca tcctcaggct gtcgggggaa
    19501 ccgatcgcga gggcgtacag cgccgggcac atgccgtcct ctctccgtgg cccggacgag
    19561 ccgcaggcag gagtgatttc ggcgaggatg acggcatgaa ccacgatcgc gtgatgggcg
    19621 tcgacgcgtg caaggccggg tgggtaggta tcactgtggc cgcaggacag gtcgatagcc
    19681 atgtcgcagc cacaatcgaa gaattggtcg ccttggccga cggaccgctt gcggtgattg
    19741 ccatcgacat gcccatcggg ttgcccgacc gcgaccagcg ggaagcagac atccttgccc
    19801 ggcaacaaat tggctcattg cggtcctcgg tgttcatgac acccgtccgc gccgttctcg
    19861 acgctaccga tcacctcacg gccagcgagc gcaatcgcca actgactggc gaaggcatct
    19921 ccattcaagc attcggcttg ttgcacaagc ttcggcaagt ggatcgatgg atccgccagc
    19981 gcccatgtca cgtcgtggaa gcccatcccg aggtcagctt cgcgcttctg gccggtgcgc
    20041 cactcaccgc acgcaagcac acatgggccg gcgcccacct gcggcggcga ctgctcactg
    20101 acgccggaat cccgctggac agcgatcttg gcgacgccgg ccggaaagcc gccgtggacg
    20161 acgtcctcga cgccgccatc tgcgcgtgga cagcacaacg cgtcgcgcgc ggccaggcac
    20221 gatccttgcc cgatccaccc caggtattca ccgacggcct accttgcgct atctggagtt
    20281 aacgacccga tggcggacag tccgggtggt tcactggtcg ccggtcccac gctgtttggc
    20341 tatcgcgtcg atttcgtcgg cgatggtgga ccacagttcg cgcggaaggt cgtggcccat
    20401 ccccgggtag ctgacgaagc gcgcaccggg gatggctgtg gcggtggccc tgcccgctcg
    20461 gatcggttgc acgggatcgg cttgtccggt cagcaccaca ctgggcaccc gtatccgaga
    20521 cagttcggca cggcggtcgc cggtggcccg ggaggcctcc ctctgtctgc gcgccgctgc
    20581 cggatccgtg cggtgctcgt aggtgcggct ggccatctcg cggagccagt cctcgtcatg
    20641 cgggtagccg gtggaaccga tgatccgcat catcccgatc aaacgctcgg cctcggcctg
    20701 tggccctgtt ccccgaacgc gcaaccccaa cgcgagcatg cggagcacga gcctgggcgt
    20761 gcgccggttc caccacaggg agggattcgg tgccgaggaa agcgaggtca ggctcagcac
    20821 acgcggctgc tggcgtaccg ccatgacctg cgcgatcatg ccaccgaggg agacgcccac
    20881 cagatgagcc gccggccagg ccagcgcgtc gagcaccgca caagcatccg cggccatatc
    20941 ggcgagtgtg taggcgcggg ggacgcgcga ggaccgcccc gaatcccggt tgtcgaacag
    21001 cgcgagccgg aacccgcgtc gtgccaactc cgtgcagaac c
//
