LOCUS       NZ_FWXV01000002        22589 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000002
VERSION     NZ_FWXV01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1569761
            Orig. end                         :: 1592350
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22589
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22589
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22589
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12589](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12589
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            28..1218
                     /gene="glf"
                     /locus_tag="B9C43_RS17000"
                     /old_locus_tag="SAMN05661093_03462"
     CDS             28..1218
                     /EC_number="5.4.99.9"
                     /GO_function="GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="glf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944957.1"
                     /locus_tag="B9C43_RS17000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03462"
                     /product="UDP-galactopyranose mutase"
                     /protein_id="WP_033381133.1"
                     /transl_table=11
                     /translation="MNFDGYDLVIVGAGFFGLTVAEQTATKLNKRVLVLERRSHIGGNA
                     YSEAEPETGIEVHKYGAHLFHTSNKRVWDYVTQFTEFTDYKHRVYTNHQGQVYPMPMNL
                     AMINQFFGRAFTPDEARQLVAEQAAEVDAKDVQNLEEKAISLIGRKLYEAFIKGYTAKQ
                     WQTDPKDLDAGIITRLPVRYNYDNRYFNDTYEGLPKNGYTAWLEKMAEHPNIEVRLNVD
                     YFDVRTQIPAGTPTVYTGPIDRYFDYSEGRLGWRTVDLEQEVVSTTGDFQGTSVMNYAD
                     EDVPFTRILEFRHFHPERDYPTDKTVIVREYARFAKEDDEPYYPINTPENRSMLERYRE
                     LIKSEAKERNIIFGGRLGTYKYLDMHMAIGSALSTFDNKVAPHLTTGAPLDGSLDA"
     gene            1211..1750
                     /locus_tag="B9C43_RS17005"
                     /old_locus_tag="SAMN05661093_03463"
     CDS             1211..1750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006238301.1"
                     /locus_tag="B9C43_RS17005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03463"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_051894985.1"
                     /transl_table=11
                     /translation="MPDSKEIAVLASVQGAIATPAVLKVARGMSFFGEHSLGWLAVGAV
                     GAAVDRERRKDWMVATGAVFAAHAASVVVKRVVRRTRPDHETVQVHVGTPSKLSFPSAH
                     ATSTTAAAVVYGALTGRRLSPMLVPPMLLSRMVLGVHYPSDVVAGSVLGAAIGGIVRRK
                     LNGRKGSHGQQSGRSD"
     gene            1722..2642
                     /locus_tag="B9C43_RS17010"
                     /old_locus_tag="SAMN05661093_03464"
     CDS             1722..2642
                     /EC_number="2.4.2.45"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632889.1"
                     /locus_tag="B9C43_RS17010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03464"
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="WP_084427450.1"
                     /sec_met_domain="ubiA (E-value: 2.5e-33, bitscore: 112.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNKVDEATEAAAPKASTSVVAGLIRTARPRQWIKNILVLAAPFT
                     ASRLTDTTVLADAGIAFVAFCLAASAVYFVNDTLDVEADRAHPTKRNRPIAAGIVPTQL
                     AWAIAAVLFLGALGISFVASWQLAVVIGVYELVQLGYCFGLKHQTVIDLCIVASGFLMR
                     AIAGGAAAGIPLSPWFLLVTAFGSLFMVSGKRYAEITLFEKTGAKIRASLAKYSASYLR
                     FVWATSAAVVIMTYGLWAFEIRQDHHNSVWSSVSMIPFVIAVLRYAVDVDGGTAGAPED
                     IALKDRVLQVLGVAWVASLALAVYI"
     gene            2654..3640
                     /locus_tag="B9C43_RS17015"
                     /old_locus_tag="SAMN05661093_03465"
     CDS             2654..3640
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016932.5"
                     /locus_tag="B9C43_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03465"
                     /product="suppressor of fused domain protein"
                     /protein_id="WP_084427452.1"
                     /transl_table=11
                     /translation="MDDAPGWSAIDAACARIYGDEKPQHWGTLLKWSLGGEDPLDGVSA
                     YTRTEPVPHWHYVSYGMSELYDKESEDADASGWGFEFTFRLVRRADQTEAPIWPANLMQ
                     NLARYVIQTGNWFAPGHHIDANGPIAADSADSLIRTLAFIQDPELGEIDTPNGAVQFLQ
                     LVGLTPDEYEAAAEWHTQALLALFEPRMPLSVTDIDRTSLLTPELLEQVRAGVERDGSN
                     SGELMVDVAEWDLSEGVTLRFGTKPAERIGRTLRGRLPFGYGLLVASAEQAVGFLPADQ
                     FSAEQSQDGILTVAIPEAALDEVVAAFRPVAGRTPVASLPGVTIEIV"
     gene            complement(3637..4395)
                     /locus_tag="B9C43_RS17020"
                     /old_locus_tag="SAMN05661093_03466"
     CDS             complement(3637..4395)
                     /EC_number="1.1.1.333"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-112). E-value: 6.9e-07.
                     Score: 21.3. Matches aSDomain:
                     nrpspksdomains_B9C43_RS17020_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944922.1"
                     /locus_tag="B9C43_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03466"
                     /product="decaprenylphospho-beta-D-erythro-pentofuranosid-
                     2-ulose 2-reductase"
                     /protein_id="WP_033381129.1"
                     /transl_table=11
                     /translation="MIDAVGSPQSLLLLGGTSEIGLAVAERYARQRPSLRVTLAGRPSD
                     RLDAAAARLREAGATVSTLPFDARQPDTHVEVIEKAFADGDIDVTIVAFGVLGDQEEAW
                     TNVDVARELAEINYVAALTIGVPLAERLRKQGHGSIVALSSAAGERARRSNFVYGSTKA
                     GFDAFYTGLTYALKPHGVTVTVVRPGFVRTKMTEGLKEAPLSQTADQVADIIVSAVRNR
                     REQVWAPAAMRGVMSILRHVPRPIFRKLPF"
     CDS_motif       complement(3964..4023)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS17020_0002"
                     /evalue="5.60E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9C43_RS17020"
                     /protein_end="144"
                     /protein_start="124"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="GVPLAERLRKQGHGSIVALS"
     aSDomain        complement(4060..4365)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS17020_PKS_KR.1"
                     /evalue="6.90E-07"
                     /label="B9C43_RS17020_PKS_KR.1"
                     /locus_tag="B9C43_RS17020"
                     /protein_end="112"
                     /protein_start="10"
                     /score="21.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="LLLLGGTSEIGLAVAERYARQRPSLRVTLAGRPSDRLDAAAARLR
                     EAGATVSTLPFDARQPDTHVEVIEKAFADGDIDVTIVAFGVLGDQEEAWTNVDVARE"
     CDS_motif       complement(4306..4362)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS17020_0001"
                     /evalue="4.10E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9C43_RS17020"
                     /protein_end="30"
                     /protein_start="11"
                     /score="9.8"
                     /tool="antismash"
                     /translation="LLLGGTSEIGLAVAERYAR"
     gene            complement(4392..5738)
                     /locus_tag="B9C43_RS17025"
                     /old_locus_tag="SAMN05661093_03467"
     CDS             complement(4392..5738)
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007025091.1"
                     /locus_tag="B9C43_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03467"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_084427454.1"
                     /transl_table=11
                     /translation="MDAELRTLAGWGRTAPSTARVVVPRTVQEVIDALRSADERGVIAR
                     GLGRAYGDPAQNAGGLVIDMTGLDRIHSIDVETATVDTAAGVSLDTLMRRLLPFGLWLP
                     VLPGTRQVSVGGAIGADIHGKAHHVEGSFCDHVESMDLVTADGQIHTLTPDDDLFWATA
                     GGMGLTGVVVRAKLKLNRVETAYFKVDTEQIDNLDELMARQSVDDDKYLESVSWFDTTA
                     TGKHLGRGILTRANHATLDDLPRKLRASPLKFDAPQLLTIPNIFPPGLLNKLTARAFCE
                     LWYRKSPTRHGAIQNITMFLHPLDILGEWNRAYGPRGFLQYQYVIPFGQEEAVKRSVRM
                     MVERGHVSLLNVLKRFGEGNRSPLSFPEPGWTLAVDLPVRRGLAELCAELDELVLTAGG
                     RLYLAKESRTTPEAIERMYPRIDEWRKVRADVDPTGIFVSDMARRLRLT"
     gene            5800..6225
                     /locus_tag="B9C43_RS17030"
                     /old_locus_tag="SAMN05661093_03468"
     CDS             5800..6225
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019811502.1"
                     /locus_tag="B9C43_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03468"
                     /product="GtrA family protein"
                     /protein_id="WP_033381127.1"
                     /transl_table=11
                     /translation="MVTAVDTGSPTGSRSVGLLTQIIRFVVVGVLAAAVDYGSYQALVA
                     MGAWVHLAKAISFILGTTTAYLINRRWTFNATGGTAPVAKFMLLYTTTFFVNVGVNALM
                     LHLLGDFRWHLTVAWVIAQGTATLINFVMLRTVVFRD"
     gene            6252..8147
                     /locus_tag="B9C43_RS17035"
                     /old_locus_tag="SAMN05661093_03469"
     CDS             6252..8147
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642804.1"
                     /locus_tag="B9C43_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03469"
                     /product="glycosyltransferase"
                     /protein_id="WP_084427456.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.2e-09,
                     bitscore: 34.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGKTAPARTSTPRARSNGRAPEKPAQLVTQRALFGGPSPLVSDD
                     LYAQVTSGTAKRSRDGVTVEPSSAVSMNTYFGRFPASYWQRWTVVREVTVELVASGTGR
                     LTVHASDYEGVSRTVASSVVAADGPVTLSAKLDRFIDGGALWLDIETGVGETLTVSQVR
                     WTVAPPETLRPTAVVICTCNRADDCLNTLEALAADPEALAVVDTIYVADQGTDTVDSRP
                     KFAEVSKKLGKKLAYIQQPNLGGAAGFTRGLFEAAKQSDHANVLFMDDDVLLEPDIAIR
                     LTAFANRTAHPVIVGGQMLNLLHPNNLHVGAEYADLEGLAAGRVSEGALSNADLLGVDA
                     SGKPNRQERRVEAGYNGWWSCLIPTEIVQAVGYPLPVFFQWDDAEYGYRAKAAGFATVT
                     LPGAAVWHADFMWKDWDDWHRYFNLRNSMITAALHSPFNTKRVARVIAAQLTRYLLSMQ
                     YGLAATMLKAVEDFLVGPSILQDGGAAVVAEIRALRAQYPDTFRHSPADVPELQNGELP
                     LIPAGPSPKNKPVRLLQQVANQLLGKHSLDRGAVSLEDATWWHVSRFANVAVTDASQEG
                     VRLRKYDRDLMLKLGKQSAAVLKRFIAEGNAIQHQYKAAMPELTSRENWARLYQL"
     gene            complement(8324..8596)
                     /locus_tag="B9C43_RS17040"
                     /old_locus_tag="SAMN05661093_03470"
     CDS             complement(8324..8596)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030625.1"
                     /locus_tag="B9C43_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03470"
                     /product="hypothetical protein"
                     /protein_id="WP_033385912.1"
                     /transl_table=11
                     /translation="MSEPKKNALVLHLASGGEPLVYALSVAAAKDMSGRLQTLMTSGAV
                     DTPELEDGSRVAINFSHVATAHFDELPPLSRVYGSAAKGGRGFRG"
     gene            complement(8593..9510)
                     /locus_tag="B9C43_RS17045"
                     /old_locus_tag="SAMN05661093_03471"
     CDS             complement(8593..9510)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657749.1"
                     /locus_tag="B9C43_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03471"
                     /product="DMT family transporter"
                     /protein_id="WP_235038655.1"
                     /transl_table=11
                     /translation="MSTKLFLILAGVLWGTGGLAGALLQNLAGLHPLAVAAYRLLLGGA
                     IATVFLSTQIRRLRFTKAVTRRLLGVGALLAIFQASYFGGVAMTSVSLATLVTIGSSPV
                     ILAVVSAVRSRRLPSPRTLLCIVLALTGLALLAGMPSTRDIWHTVIGIALCLVAASGFA
                     AFTVINRVPVLPAGPTISLGLLIGGLILLPVALPLGMALPLRFDVLMTALFLGLVPTAV
                     AYGSYLLALRGASAVAAALSAVLEPLTATVLSVLFFNESLGAVGVIGAVLLGIALAVNY
                     SAESGSAQSEPSLPVRRPDAGVGT"
     misc_feature    9826..9842
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.56"
                     /tool="antismash"
     misc_feature    complement(9830..9844)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.96"
                     /tool="antismash"
     misc_feature    9905..9920
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            10001..12589
                     /gene="lanKC"
                     /locus_tag="B9C43_RS17050"
                     /old_locus_tag="SAMN05661093_03472"
     CDS             10001..12589
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642932.1"
                     /locus_tag="B9C43_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03472"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_084427460.1"
                     /sec_met_domain="micKC (E-value: 5.9e-268, bitscore: 888.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.1e-08, bitscore: 31.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 5.2e-09, bitscore: 33.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYEAFCFADRYFYDADGYGIETLESWVSSLSGCATGWHRFDR
                     GDWHVCLPEGVDLPMQGWKVHVAATGADAARVLEVVRPYCVAARLPFKFLRSPRIYANR
                     NAKYADRSASGKLITIYPTGDRQLKRVLDDLNRQLDGVRGPYIPGDLRYADGPLYVRYG
                     GFVERMITDSRGAVIPALERPDGEVVPEPVGLPDWLEVPDYLSPHLNAQQPGEASRYQV
                     VKVLQQTNAGGVYLAHRRSDGRQVVLKEARPHTGLDPDGTDAVTRLDREARTLIRLSGV
                     PGTPELQGRISVAGNEVLLISPMPGVPLSRWLARNYPLTQRDLTKSDRSRYVERALALL
                     ARVERILADVHRRGLVYGDLNDRNIIVDDDDSVSLVDFELAFPAVDRRRPSGGTPGFRA
                     PVDRSGYEVDRYAFAVLRLWMFLPMTMVLDLEPDKLADFVRQVRKRFDLPLGYLEEVLA
                     ELRPRSARSARRRTPLDQPEINWTSVRRSIADGVLASATPHRTDRLFPGDIQQFATGGT
                     GFGYGAAGVLHALDVSGFGRFPAHEKWLIDAVRRQPPATAGFWDGAHGTIHVLDNFGYH
                     DDADELIEKVEPQLSSITCHSLRTGLAGIGLNLLHLAANRQDAGHLWHAIEIGGRLTHM
                     LENAPLPTRGRAGLMHGWSGPALLFLRLFERTRDRSWLDHADLAIRRDLMECARTPDGS
                     LQVRDRQNTLPYLEVGSAGIAIAMEELLTAWPAAPVASELPRLRRALLAEFVIQPGLML
                     GRAGLIGALATGLRREPDPLASRALDQHLEWLALHAVPYQGHVAFPGTHLFRLSMDVAT
                     GSAGVLLALASALDGVQLLPFLSDNTALAVFGLESVSSGRSVRVGPGGRA"
     misc_feature    12296..12298
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12543..13442)
                     /locus_tag="B9C43_RS17055"
                     /old_locus_tag="SAMN05661093_03473"
     CDS             complement(12543..13442)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012795670.1"
                     /locus_tag="B9C43_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03473"
                     /product="glycosyltransferase"
                     /protein_id="WP_033385914.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.8e-12,
                     bitscore: 44.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKALGPDSVVAVVVTRHRRELLVDSLKILGAQTRPPDHLIVVDN
                     GPDQPVEDLVNAAAVPSTYLASHRNLGGAGGFALGILHALAMGAEWVWLADDDGRPADE
                     NVLEVLLSEAKRRGLAEISPVVANINTPETLAFPLRRGLTWKRQTSELGTDFLPGIASL
                     FNGALFRASTLDVVGVPDYRLFVRGDEVEVHRRLVRSGLPFGTSLRVTYLHPDGSDEFK
                     PMLGGRFHAQDPDNDVKRYYTYRNRGYLLSRPGMRKIGALEVLRFGLYFLTVRKDPKAF
                     VQWLKLVRQGQREHFFRY"
     gene            complement(13439..14245)
                     /locus_tag="B9C43_RS17060"
                     /old_locus_tag="SAMN05661093_03474"
     CDS             complement(13439..14245)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026253.1"
                     /locus_tag="B9C43_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03474"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_033385916.1"
                     /transl_table=11
                     /translation="MVSIDVWNASVDFPIFDAKTRSLKKAVLGKVGGTIGTDSKIPVIE
                     ALKDINLSLKDGDRVALVGHNGAGKSTLLRLLSGIYEPVTGGSKIVGKIAPVFDLGVGM
                     DPEISGIENIMIRGLFLGMSRKQMESKIDDIAEFSELGDFLQMPLRAYSTGMRVRLALG
                     IVTSIDPEILILDEGIGAVDAAFMDKARDRLTDLVKRSGLLVFASHSDDLLMELCDSAI
                     WMDGGRMKMQGSLREVLTAYKGRDPYENLSQEMLERLGVTAGGDPR"
     gene            complement(14263..15162)
                     /locus_tag="B9C43_RS17065"
                     /old_locus_tag="SAMN05661093_03475"
     CDS             complement(14263..15162)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005460975.1"
                     /locus_tag="B9C43_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03475"
                     /product="ABC transporter permease"
                     /protein_id="WP_084428258.1"
                     /transl_table=11
                     /translation="MTAAEKPLDNPSRTFGRAWEDIRSGIKQRDLWGHLGWQDIKQRYR
                     RSVIGPLWITMSMAVTAAGLGILYSTLFKANIGTFLPYLTVGFIVWNFIVGCVTEGTET
                     FIANEGLIKHLPAPLTVYALRTVWRLTLMMAHNLLVYFVVLAIFFGALTTANYQMTAGG
                     ILQPGLDWTVVLAIPAFFLIALNGVWVALLFGIISTRYRDIPQVINALIQLVFFMTPIV
                     WSADILHDRLGAGTELWKTLVLELNPLYHYVEIIRAPLIGSAQSWHHWVIVGGITLIGW
                     ALALVALRNYRARVPYWV"
     misc_feature    complement(15229..15244)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            complement(15293..15769)
                     /locus_tag="B9C43_RS17070"
                     /old_locus_tag="SAMN05661093_03476"
     CDS             complement(15293..15769)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020674067.1"
                     /locus_tag="B9C43_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03476"
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="WP_160096536.1"
                     /transl_table=11
                     /translation="MIGYDTVSGQATFDIRGVIGPDNGPPCPADRRYVDEQPKGLRDDV
                     LPEFEKIKAAARSQNVTLCLNDGKRSSRQQQAQFDDYVRRYGSVEEARKHVLPAGRSMH
                     ELGTAIDVQPLSAAGWLERTAGSYGWCRRYENEPWHFEYDPGYRNGCPAMLPHA"
     gene            complement(15890..16432)
                     /locus_tag="B9C43_RS17075"
                     /old_locus_tag="SAMN05661093_03477"
     CDS             complement(15890..16432)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005442844.1"
                     /locus_tag="B9C43_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03477"
                     /product="bacterial proteasome activator family protein"
                     /protein_id="WP_200825556.1"
                     /transl_table=11
                     /translation="MSQPEQNGKDDAHHVVVVGPDGSPLGAARIPDGSDEGDKPETIGD
                     MVEQPAKVMRIGTMIKQLLEEVRAAPLDEASRTRLKEIHASSIKELEEGLAPELRAELD
                     RLTLPFTDDSVPSDAELRIAQAQLVGWLEGLFAGIQTALFAQQMSARVQLEQMRRGALP
                     PGLGEQQPHDTTRGQYL"
     gene            16537..17739
                     /locus_tag="B9C43_RS17080"
                     /old_locus_tag="SAMN05661093_03478"
     CDS             16537..17739
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (19-391). E-value: 8.7e-43.
                     Score: 138.5. Matches aSDomain:
                     nrpspksdomains_B9C43_RS17080_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030643.1"
                     /locus_tag="B9C43_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03478"
                     /product="cysteine desulfurase-like protein"
                     /protein_id="WP_084427464.1"
                     /sec_met_domain="Aminotran_5 (E-value: 9.2e-40, bitscore:
                     133.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFDVARIRGLFPALGDGWIHLDASAGMQVPEQVAMAVATAMRAP
                     VSGPGGAFPASQRAEAIVDAARRAVADLVGGDPAGVVLGPNVPVLLQRLAESMGSGWLI
                     GDEVAVSRLDHQANIAPWLRAAQRPGAAIRWGEIDIETCELPAWQYESLMSRRTKVVAV
                     TAASGAVGTRPDVRKIADIAHSVGALLVVDASAAAPYMPIDMKAMGADIIAVSASAWGG
                     PAVGALVFADPDLLDRLPVSSLDPGTRGPERLELGAHAYPLLAGLVASVDYLAMLDDTA
                     TGTRRERLQTSLSSAKSYLAGLLAKLISELRAIRNVMVIGDAMRRIPVLAFTIGDMKAS
                     DAIVALADRGICAFADDVPSGVFTALGVSEVGGAVRVGLAHYSTSSEVDQLVDAVAELR
                     H"
     aSDomain        16594..17709
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS17080_Aminotran_5.1"
                     /evalue="8.70E-43"
                     /label="B9C43_RS17080_Aminotran_5.1"
                     /locus_tag="B9C43_RS17080"
                     /protein_end="391"
                     /protein_start="19"
                     /score="138.5"
                     /tool="antismash"
                     /translation="IHLDASAGMQVPEQVAMAVATAMRAPVSGPGGAFPASQRAEAIVD
                     AARRAVADLVGGDPAGVVLGPNVPVLLQRLAESMGSGWLIGDEVAVSRLDHQANIAPWL
                     RAAQRPGAAIRWGEIDIETCELPAWQYESLMSRRTKVVAVTAASGAVGTRPDVRKIADI
                     AHSVGALLVVDASAAAPYMPIDMKAMGADIIAVSASAWGGPAVGALVFADPDLLDRLPV
                     SSLDPGTRGPERLELGAHAYPLLAGLVASVDYLAMLDDTATGTRRERLQTSLSSAKSYL
                     AGLLAKLISELRAIRNVMVIGDAMRRIPVLAFTIGDMKASDAIVALADRGICAFADDVP
                     SGVFTALGVSEVGGAVRVGLAHYSTSSEVDQL"
     gene            complement(17949..18926)
                     /locus_tag="B9C43_RS17085"
                     /old_locus_tag="SAMN05661093_03479"
     CDS             complement(17949..18926)
                     /NRPS_PKS="Domain: PKS_ER (12-323). E-value: 1.8e-55.
                     Score: 180.2. Matches aSDomain:
                     nrpspksdomains_B9C43_RS17085_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097624.1"
                     /locus_tag="B9C43_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03479"
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="WP_084427466.1"
                     /sec_met_domain="ADH_N (E-value: 3.2e-11, bitscore: 39.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.8e-23, bitscore:
                     79.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYAIVAREPGGPDVLEWTEVPDPQAGPGEVLIDIAASAVNRADLL
                     QRQGFYPPPPGAPNIIGLECSGTIAALGEGVTNWEVGDEVCALLAGGGYGQRVAVPATQ
                     VLPLPDGVDLVTAASLPEVACTVWSNIVQHAGLQSGEILLIHGGAGGIGTHAIQVGKAL
                     GATVAVTAGSDERLERCASLGADITINYKTQDFVEVLGKRGADVILDNMGASYLDRNLT
                     ALANDGRLMVIGFQGGRKAELDFSKMLPKRASVTSLGLRGRPVSGRGSKGEVVAGVREG
                     LWPLIAEGKVKPIVHEVRPMQDASGAHAALESGGEVFGKIILKP"
     aSDomain        complement(17958..18890)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS17085_PKS_ER.1"
                     /evalue="1.80E-55"
                     /label="B9C43_RS17085_PKS_ER.1"
                     /locus_tag="B9C43_RS17085"
                     /protein_end="323"
                     /protein_start="12"
                     /score="180.2"
                     /tool="antismash"
                     /translation="DVLEWTEVPDPQAGPGEVLIDIAASAVNRADLLQRQGFYPPPPGA
                     PNIIGLECSGTIAALGEGVTNWEVGDEVCALLAGGGYGQRVAVPATQVLPLPDGVDLVT
                     AASLPEVACTVWSNIVQHAGLQSGEILLIHGGAGGIGTHAIQVGKALGATVAVTAGSDE
                     RLERCASLGADITINYKTQDFVEVLGKRGADVILDNMGASYLDRNLTALANDGRLMVIG
                     FQGGRKAELDFSKMLPKRASVTSLGLRGRPVSGRGSKGEVVAGVREGLWPLIAEGKVKP
                     IVHEVRPMQDASGAHAALESGGEVFGKIIL"
     CDS_motif       complement(18450..18509)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS17085_0002"
                     /evalue="2.10E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="B9C43_RS17085"
                     /protein_end="159"
                     /protein_start="139"
                     /score="14.0"
                     /tool="antismash"
                     /translation="GEILLIHGGAGGIGTHAIQV"
     CDS_motif       complement(18708..18746)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS17085_0001"
                     /evalue="2.10E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="B9C43_RS17085"
                     /protein_end="73"
                     /protein_start="60"
                     /score="11.1"
                     /tool="antismash"
                     /translation="IGLECSGTIAALG"
     gene            18970..19608
                     /locus_tag="B9C43_RS17090"
                     /old_locus_tag="SAMN05661093_03480"
     CDS             18970..19608
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012782774.1"
                     /locus_tag="B9C43_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03480"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_084427468.1"
                     /transl_table=11
                     /translation="MDPWPLRNLVIRTPRLELRPDDDAGLFELVEVAKAGVHAPDKMPF
                     GVPWTDRPPIEWVKFYWGQRAAFSPDDWSLNFLTRVDGRVVGMQGAVAKDFAVTREIHT
                     GSWLGLAHQGKGYGTEMRAAVVMFAFDYLGAERMTSAAHSDNRASHTVSRKLGYRPDGV
                     ERQSIKGKLVFNERLALTPEQFVRPEWSIEVDGLDGCRSLLVSEPLGRM"
     gene            19686..20123
                     /locus_tag="B9C43_RS17095"
                     /old_locus_tag="SAMN05661093_03481"
     CDS             19686..20123
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016289.5"
                     /locus_tag="B9C43_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03481"
                     /product="M28 family peptidase"
                     /protein_id="WP_327222586.1"
                     /transl_table=11
                     /translation="MGSGPGPTGSGPIEAALAARFAAAPTEGKDFDGRSDYGEFIAQGI
                     PAGGTFTGAEVIKTAEQAAKWGGQAGVAFDKCYHQACDNLFNVNRAALAKQAAAISYVI
                     TAYGISTEDVNGVPPRSERAQARAVAKTVSVSATHDHDAVS"
     gene            complement(20195..21118)
                     /locus_tag="B9C43_RS17100"
                     /old_locus_tag="SAMN05661093_03482"
     CDS             complement(20195..21118)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986215.1"
                     /locus_tag="B9C43_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03482"
                     /product="neutral zinc metallopeptidase"
                     /protein_id="WP_084427472.1"
                     /transl_table=11
                     /translation="MEFNDDAGLDTSQVEDMRSSGGGVGGRVLLGGGGLSIVGLIIYFV
                     MSQFGGVAGLDGNSASGLGDVTSGQRVDNARISEQCRTGRDANTNHDCALVAVINSIQG
                     YWRDQFARSGQTYQQAPTNFFRGGVTTGCGSATADVGPFYCPADSEVYIDLSFFTQLQS
                     QFGAQGGTFVEAYVLAHEYGHHVQNLLGTSDRVRTRRGPTSDAVRLELQADCYAGVWAN
                     HATTTPSANGGPPLIRNITEDDIRRALDAAGRIGDDFIQRELGGGRVDESQFTHGTSQQ
                     REKWFTTGIQSGNPAQCDTFRTNNLG"
     misc_feature    21444..21459
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     gene            21545..22033
                     /locus_tag="B9C43_RS17105"
                     /old_locus_tag="SAMN05661093_03483"
     CDS             21545..22033
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024212.5"
                     /locus_tag="B9C43_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_03483"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_084427474.1"
                     /transl_table=11
                     /translation="MGDTVDKIIQQWRHERPELDLAPMAVTARLTRLAALLERGVDDTL
                     AAQGLASWEFEVLASLRRNGSPFVLSVGRLQATMMISSGTMTHRLDRLEKRGLVARSKD
                     LNDRRGIQVSLTPDGRTLIDNVIEARLARERDLLTTLDKDQQTNLASLLRGLLTAMEQ"
     tRNA            complement(22247..22333)
                     /anticodon=(pos:complement(1592058..1592060),aa:Ser,
                     seq:tga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="B9C43_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN05661093_03484"
                     /product="tRNA-Ser"
     gene            complement(22247..22333)
                     /locus_tag="B9C43_RS17110"
                     /old_locus_tag="SAMN05661093_03484"
ORIGIN
        1 gcagtcgagt cggtaccctc agcgcccgtg aacttcgatg gctatgacct ggtaatcgtc
       61 ggtgccggat tcttcggcct cacggtcgcg gagcagaccg cgacgaagct gaacaagcgc
      121 gtcctggtgc tcgagcgccg gtcgcacatc ggtggcaacg cgtactcgga ggccgagccg
      181 gagaccggca tcgaggtcca caagtacggt gcgcacctgt tccacacttc gaacaagcgc
      241 gtgtgggact acgtgaccca gttcaccgag ttcaccgact acaagcaccg ggtctacacc
      301 aaccaccagg gccaggtgta cccgatgccg atgaacctgg cgatgatcaa ccagttcttc
      361 ggccgcgcgt tcaccccgga cgaggcccgc cagctcgtcg ccgagcaggc cgccgaggtc
      421 gacgccaagg acgtgcagaa cctcgaggag aaggcgatct cgctgatcgg ccgcaagctc
      481 tacgaggcgt tcatcaaggg ctacaccgcc aagcagtggc agaccgaccc gaaggacctg
      541 gacgcgggca tcatcacgcg cctgccggtc cgctacaact acgacaaccg gtacttcaac
      601 gacacctacg agggcctgcc caagaacggg tacaccgcgt ggctggagaa gatggccgag
      661 cacccgaaca tcgaggtgcg gctgaacgtg gactacttcg acgtccgcac ccagatcccg
      721 gctggtactc cgaccgtcta caccggaccg atcgaccgct acttcgacta ctccgaaggc
      781 cggctgggct ggcgcacggt cgacctcgag caggaagtcg tctcgaccac cggtgacttc
      841 cagggcacct cggtgatgaa ctacgccgac gaggacgtgc cgttcacccg gatcctggag
      901 ttccgccact tccacccgga gcgggactac ccgaccgaca agaccgtcat cgtccgggag
      961 tacgcgcgct tcgccaagga agacgacgag ccgtactacc cgatcaacac ccccgagaac
     1021 cgcagcatgc tggagcgcta ccgcgagctc atcaagagcg aggccaagga gcgcaacatc
     1081 atcttcggtg gccgtctcgg tacctacaag tacctcgaca tgcacatggc catcggatcc
     1141 gcgctgagca cgttcgacaa caaggtcgcg ccgcacctga ccacgggtgc accgctcgac
     1201 gggtcgcttg atgcctgatt cgaaggagat cgcggtcctg gcttcggtgc agggcgcgat
     1261 tgcgactccc gcggtgctca aggtcgcccg cgggatgtcg ttcttcggtg agcacagcct
     1321 tgggtggctc gcggtcgggg cggtgggtgc cgccgtcgac cgcgagcgcc gtaaggactg
     1381 gatggtggcc accggcgctg tgttcgccgc tcacgccgcg tccgttgtgg tcaagcgcgt
     1441 cgtcaggcga acgaggccgg atcacgagac tgtgcaggtg catgtcggta cgccgtcgaa
     1501 gctgagcttc ccgtcggcgc acgcgacctc gacgacagcc gccgccgttg tttatggagc
     1561 ccttaccggc aggcggctat caccgatgtt ggttccgccg atgctcctgt cgaggatggt
     1621 gctcggcgtg cactacccca gtgacgtggt ggccggctcc gtcctcggtg ccgccatcgg
     1681 cgggatagtg cgccgcaagc tgaacggcag gaaaggaagc catgggcaac aaagtggacg
     1741 aagcgactga agctgcggcg cccaaggcat cgaccagcgt ggtcgccggc ctgatcagga
     1801 ccgcgcggcc acgtcagtgg atcaagaaca tcctggtgct ggccgcgccg ttcaccgcgt
     1861 cgcggctcac cgacaccacg gtcctggctg acgccggtat cgcgttcgtc gcgttctgcc
     1921 tcgcggcttc ggccgtgtac ttcgtcaacg acacgttgga cgtcgaggcc gaccgcgcac
     1981 acccgaccaa gcgcaaccgg ccgattgcgg ccgggatcgt gcccacgcag cttgcctggg
     2041 ccatcgcggc cgtgctgttc ctcggcgcgc tcggcatctc gtttgtggcc agctggcagc
     2101 tggccgtcgt gatcggcgtg tacgagctcg tccagctcgg ttactgcttc ggcctgaagc
     2161 accagacagt gatcgacctg tgcatcgtgg cctccggctt cctgatgcgc gcgatcgccg
     2221 gtggcgcggc cgcgggtatc ccgctttcgc cgtggttcct gctggtcacc gcgttcggct
     2281 cgctgttcat ggtgtccggc aagcgctatg ccgagatcac cctgttcgag aagaccggcg
     2341 cgaagatccg ggcgtcgctg gccaagtact cggccagcta cctgcggttc gtctgggcga
     2401 cttcggccgc tgtggtgatc atgacctacg gcctgtgggc gttcgagatc cggcaggacc
     2461 accacaactc ggtctggtcc tcggtgtcga tgatcccgtt cgtcatcgcc gtgctgcgct
     2521 acgccgtcga cgtcgacggc ggtacggctg gggcgccgga ggacatcgcg ttgaaggacc
     2581 gtgtcctgca ggtgctcggg gtcgcgtggg tcgcgtccct cgcgttggcg gtctatatct
     2641 aggctcctcc ggcatggacg atgcccccgg ctggtcagcg atcgacgcgg cgtgtgcgcg
     2701 gatctacggc gacgagaagc cccagcactg gggaacgctg ctgaaatggt cgttgggcgg
     2761 cgaggacccg ctcgacggcg tcagcgcgta cacgcggacc gagcccgtgc cgcactggca
     2821 ttacgtcagc tacggcatgt ccgagttgta cgacaaggaa tccgaggacg cggacgcctc
     2881 cggctggggc ttcgagttca cgttccggct ggttcgccgg gctgaccaga ccgaggcccc
     2941 gatctggccg gcgaacctga tgcagaacct ggcccgctac gtcatccaga cgggcaactg
     3001 gttcgcgccc ggccatcaca tcgacgcgaa cggcccgatc gcggcggaca gtgcggactc
     3061 actgattcgt acgctcgcgt tcatccagga ccccgagctc ggcgaaatcg acacccccaa
     3121 cggcgccgtg cagttcctcc agctcgtcgg gctcacgccg gacgaatacg aggctgcggc
     3181 cgagtggcac acacaagccc tgttggcgtt gttcgagccc cggatgccgc tgtccgtcac
     3241 ggacatcgac cggacgtcgc tgctgacgcc tgagctgctc gagcaagtcc gggcaggcgt
     3301 tgagcgggac ggctcgaaca gcggcgagct gatggtcgac gtggccgagt gggacctgag
     3361 cgagggcgtg acgttgcggt tcggcacaaa gcccgccgaa cgcatcggtc gcacgctgcg
     3421 cggcaggctg cccttcggct acggcctgct ggtcgcgtct gccgagcaag ccgtcggttt
     3481 cctgccggcg gaccagttct ccgccgagca gtcccaagac gggatcctga ctgtggccat
     3541 ccccgaggct gccctcgacg aggtggtcgc ggcgttccgc cccgtcgcgg ggcggacgcc
     3601 ggttgcctct ttgcctggtg tgacgatcga gatcgtctag aacggcagct tgcggaagat
     3661 cggtcgcggc acgtgccgca ggatcgacat cacgccacgc atggccgcgg gcgcccatac
     3721 ctgctcgcgg cggttacgca cggcactgac gatgatgtcg gcgacctggt cggcggtctg
     3781 cgacagcggg gcctccttca ggccctcggt catcttcgtg cgcacgaagc ccggccggac
     3841 gaccgtcacg gtcacaccgt gcggcttcag ggcgtacgtc aggcccgtgt agaaggcatc
     3901 gaagccggcc ttggtcgagc cgtacacgaa gttcgaccgg cgagcgcgct caccggcagc
     3961 ggacgacaac gcgacgatcg agccatggcc ctgcttgcgc aggcgctcgg caagcggcac
     4021 gccgatggtc aacgcggcca cgtagttgat ctcggcgagc tcgcgcgcga cgtcgacgtt
     4081 cgtccacgcc tcttcctggt caccgagcac gccgaacgcc acgatcgtca cgtcgatgtc
     4141 gccgtccgcg aacgccttct cgatcacctc gacgtgtgtg tcgggctgcc gggcgtcaaa
     4201 cggcagcgtg ctgacagtcg cgcccgcctc gcgcagccgc gcggccgcgg cgtcgagacg
     4261 gtcggacggg cggcccgcca acgtgacccg caacgacggg cgctgacggg cgtatcgctc
     4321 agcgaccgct aggccgatct cggaggtgcc gccgagcaac aacagggact gtgggctgcc
     4381 aaccgcgtcg atcacgtaag cctcaacctt ctggccatat cggagacaaa gattccggtc
     4441 gggtcgacat cggcgcgcac ctttcgccat tcgtcgatcc gggggtacat cctctcgatc
     4501 gcctcgggcg tcgtcctgga ctccttggcc aggtacagcc gcccaccggc ggtcagcacg
     4561 agctcgtcga gctcggcaca cagttccgcg agaccgcgcc ggaccggcag gtcgactgcc
     4621 agcgtccagc ccggctcggg gaacgacaac ggggaccggt tgccttcacc gaaccgtttg
     4681 agaacgttca acagcgagac gtggccacgc tcgaccatca tccgcacgct gcgtttgacc
     4741 gcttcttcct ggccgaacgg gatgacgtac tggtactgca ggaagccgcg tggcccgtag
     4801 gccctgttcc actcgccgag gatgtccagc gggtgcagga acatcgtgat gttctggatc
     4861 gcgccgtgcc tggtcggcga tttgcggtac cagagctcgc agaacgcccg cgcggtcagc
     4921 ttgttcagca gcccgggcgg gaagatgttc gggatggtca gcagctgagg tgcgtcgaac
     4981 ttcaacgggc tggcccgcag cttgcgcggc aggtcgtcga gcgttgcgtg gttcgccctg
     5041 gtcaggatgc cgcggccgag gtgcttgccg gtggctgtgg tgtcgaacca ggagaccgac
     5101 tcgaggtact tgtcgtcgtc gaccgactgc cgggccatca gctcgtcgag gttgtcgatc
     5161 tgctcggtgt cgaccttgaa gtacgccgtc tcgacccggt tgagcttcaa cttcgcccgc
     5221 acgaccacgc cggtgaggcc catgccgccc gcagtcgccc agaacaggtc gtcgtccggt
     5281 gtgagcgtgt ggatctggcc gtccgcggtg accaggtcca tggactcgac gtggtcgcag
     5341 aaactgcctt ccacgtggtg tgccttgccg tggatgtcgg cgccgatcgc gccgcccacg
     5401 ctgacctgcc gcgttcccgg cagcaccggc agccagaggc cgaacggcag cagcctgcgc
     5461 atcagcgtgt ccaggctcac gccggcggcg gtgtcgaccg tggcggtctc cacgtcgatg
     5521 gagtggatcc gatccaggcc cgtcatgtcg atgaccaggc cacccgcgtt ctgcgcaggg
     5581 tcgccgtacg cacggccgag gccgcgtgcg atgacgccgc gctcgtcggc ggaccgcagc
     5641 gcatcgatca cttcctggac ggtccgtggg acgacgactc gcgcggtact cggcgctgtc
     5701 cggccccagc cggccagcgt tcgcaactcg gcatccaccc ggctgagcgt acccagcgcc
     5761 gacttttaga ctgcttgggg cgccgagcag tgaggaatca tggtgacggc agtggacact
     5821 ggctctccca ccggttcgcg aagtgtgggt ttgctcaccc agatcatccg ttttgtcgtg
     5881 gtcggcgtgc tggccgcggc ggtggactac ggcagctacc aggcactggt ggcaatgggc
     5941 gcgtgggtgc acctggccaa ggcgataagc ttcatcctcg gtaccaccac cgcctacctg
     6001 atcaaccggc gttggacgtt caacgccacg ggcggtaccg cgccggtcgc gaagttcatg
     6061 ctgctctaca ccacgacgtt cttcgtgaac gtgggtgtga acgcgctgat gctgcacctg
     6121 ctcggtgact tccggtggca cctcaccgtg gcgtgggtga tcgcccaggg cacggctaca
     6181 ttgatcaact tcgtgatgct gcggaccgtg gtgttccgcg actgagagcc gtcctggagg
     6241 actgaggcgc gatgcccggc aaaaccgcac cggcccggac cagcacgccc cgcgcgcgga
     6301 gcaacggtcg cgccccggag aagcccgccc agctggtcac ccagcgcgcc ctgttcggcg
     6361 gcccgtcgcc gctcgtcagc gacgacctct atgcccaggt gacctccggc acggccaagc
     6421 gctcgcgtga cggtgtgacc gtcgagccgt cgtcggccgt gtcgatgaac acgtacttcg
     6481 gccgcttccc cgcgagctac tggcagcgct ggacggtcgt gcgcgaggtg accgtcgagc
     6541 tcgtcgcgtc aggcaccgga cgcttgaccg tgcacgcctc ggactacgag ggcgtgtccc
     6601 ggaccgtcgc ctcatcggtt gttgccgctg acggcccagt cacgttgtcc gccaaactcg
     6661 accggttcat cgacggcggc gcgttgtggc tcgacatcga aaccggcgtc ggcgagacgc
     6721 tgaccgtgtc acaggtccgc tggaccgtcg ccccgccgga gaccttgcgc ccgacggcag
     6781 tggtgatctg cacgtgcaac cgtgccgatg actgcctgaa caccctcgaa gccctggccg
     6841 cggaccccga agcacttgcc gtggtggaca cgatctatgt ggccgaccaa ggcacggaca
     6901 cggtggactc acggccgaag ttcgctgagg tatcgaagaa actgggcaag aagctggcgt
     6961 acatccagca gccgaacctc ggcggcgccg caggcttcac ccgtgggttg ttcgaggccg
     7021 ccaagcaatc cgaccacgcg aacgtcctgt tcatggacga cgacgtgttg ctggagccag
     7081 acatcgcgat ccgcctgacg gcgttcgcca accgcacggc acacccggtg atcgtcggcg
     7141 gccagatgct gaacctgctg caccccaaca acttgcacgt cggtgcggag tacgcggacc
     7201 tggaaggcct tgccgcggga agggtttccg aaggcgcgtt gtccaatgcg gacctgcttg
     7261 gcgtggatgc ctccggcaag ccgaaccgcc aggaaaggcg agtggaagcg ggctacaacg
     7321 gctggtggtc ctgcctgatc cccacggaga tagtccaagc ggtcggctac ccactgccgg
     7381 tgttcttcca atgggacgac gcggaatacg gctaccgcgc caaagccgcc ggcttcgcca
     7441 cggtgacatt gccgggcgcg gcggtatggc acgccgattt catgtggaaa gactgggacg
     7501 actggcacag gtacttcaac ctgcgcaact cgatgatcac ggcagccctg cacagcccgt
     7561 tcaacaccaa gcgcgtcgcc cgagtgatcg ccgcccaact gacccgatac ctgctgtcga
     7621 tgcagtacgg cctagcggcc acgatgctca aagcagtaga agacttcctc gtcggcccat
     7681 cgatcctgca ggacggcggc gcggcggtgg tagcggagat ccgcgcccta cgcgcccaat
     7741 acccggacac attccgccac agtccagcgg atgtgccgga actgcagaac ggcgaactgc
     7801 ccctgatccc agcaggccca tcgcccaaga acaagccggt gcgcctgctc caacaagtcg
     7861 ccaaccagtt gctgggcaag cactcactgg acaggggagc ggtcagcctc gaggacgcaa
     7921 cctggtggca cgtctcgcgg ttcgcgaacg tagccgtgac ggacgcatcc caggaaggcg
     7981 tccgcctgcg caaatacgac cgcgacctga tgctcaagct aggcaagcag tccgcagccg
     8041 tgctcaagcg cttcatagcc gaaggcaacg cgatccagca ccagtacaag gcagcaatgc
     8101 cagagctgac cagccgcgaa aactgggccc gcctctacca actctgacgg ccacggccca
     8161 tttgacacca accggcccag aacaggcccc ggccactccc gggggcgacc ccgctgccag
     8221 tctatcggga tatgggcagg tcaaccgggc taccagcggg ttgtagacag ctggatttgc
     8281 gaacggtccg ttcgcgcgaa aggccgcaaa cggaccgtct cacctacccc ctgaagccgc
     8341 ggccgccctt ggctgcgctg ccgtacaccc gtgacagcgg tggcagttcg tcgaagtgcg
     8401 cggtggccac gtggctgaag ttgatggcga cgcgtgagcc gtcctccaac tcgggggtgt
     8461 ccactgcgcc ggacgtcatc aacgtctgca gtcggccgct catgtctttg gcggccgcca
     8521 cggacagcgc gtacaccagt ggctccccgc cgctcgcgag gtgcagcacg agggcgttct
     8581 tcttgggctc gctcatgttc ccactccagc atcgggccgc cggaccggca acgacggttc
     8641 actctgagca gatccgctct cggcggaata gttcaccgcc agtgcgattc cgagcagcac
     8701 cgcgccgatc acgccgacgg ccccgagcga ttcgttgaag aacagcaccg acaacactgt
     8761 tgcggtcaac ggttcgagca ccgctgacag tgctgcggcc actgcactcg cgcctcgcag
     8821 agcgagcaaa tacgagccgt acgccaccgc ggtgggcacc aagcccaaga acaacgctgt
     8881 catcaaaacg tcgaaccgca aaggcaaagc catgcccagt ggcaacgcga cgggcagcaa
     8941 gatcagcccg ccgatcagca ggcccagtga gatcgttggt cccgccggga gtacgggaac
     9001 ccggttgatc acggtgaatg ccgcgaatcc ggacgccgcc acgagacaca gcgcgattcc
     9061 gataacggtg tgccagatgt cccgtgtgga cggcatcccc gccagcaatg ccagtccggt
     9121 caacgccagc acgatgcaca acagcgttcg cggactggga agccgtcggg agcggacggc
     9181 gctgaccacg gcgaggatca ccggcgagct gccgatggtg accaacgtgg cgaggctgac
     9241 cgaagtcata gccacgccac cgaagtaact agcttggaag atcgccagca gcgcgccgac
     9301 tcccagcagc cttcgtgtca ccgctttggt gaaccgcagg cgtcggatct gtgtggacag
     9361 aaacaccgtt gcgatggctc cgccgaggag caggcggtac gccgccaccg ccaatgggtg
     9421 caggcctgcc aggttttgca gcagtgcgcc tgccaggccg ccggttcccc agagcacacc
     9481 ggcaaggatc agaaacagct tggtagacaa ggaaaaacgc tccagcgcag aaggaacagg
     9541 tgctgttcgt ccgcggggcg atcaggcatg gttcacagcg cgcggcagtc acatccgcgc
     9601 gtggtggcag ctcagccccg cctaggcggc cggcggcggg gtgatcggaa acatgcgatg
     9661 cacgtcaagc acattaatgc cgttgtcaag cgtcattgga gtgaacctct tatcaggcga
     9721 cacactctcg gtagatccac tactctccgt agctgccgat agtccgggcc ggaccgtgcg
     9781 gcaatgctgc atatggcgga gtcgcaagcg gcgatcgggt ggttttcgtc attttctgac
     9841 agaccgctct cggatactcg ggagtagtaa atgcgtccag tcgtctaatt ggcagtgtga
     9901 accctcgaac ggcggatcga cctgccggtt ggtttcgtgc ggaaattatt tcctgcttgg
     9961 gcgcgaatgg cggatttcga taggggaggc gcttgccggc atggatctgc gttatgaggc
    10021 gttctgtttc gcggatcgtt acttctatga cgccgatggt tatggaatcg agacgctgga
    10081 aagctgggtc agttcgcttt ctggttgtgc cacgggctgg caccggttcg accgcggcga
    10141 ctggcacgtc tgtcttcccg agggtgtgga cctgccgatg caggggtgga aggtgcacgt
    10201 ggccgcgacc ggcgccgatg ccgcacgggt gctcgaagtg gtgcggccct actgcgtcgc
    10261 cgcccggctg cccttcaaat tcctgcgctc accccgtatt tacgcgaatc gtaacgcgaa
    10321 gtacgccgat cggtcggcga gtggaaaatt gatcacgatt tacccgaccg gggaccggca
    10381 gctgaaacgc gttcttgacg acctgaaccg ccaactggac ggcgtgcgtg gtccgtatat
    10441 ccctggcgac ttgcgctatg cagatgggcc gctttacgtg cggtacggcg gatttgtcga
    10501 acgtatgatc accgattcac ggggtgcggt gataccggcg ctcgaacgcc cggacggcga
    10561 agtcgttccc gagccggttg gcctgcccga ctggctcgaa gtgcccgatt acctcagccc
    10621 gcacctcaac gcacagcaac caggcgaggc ttcgaggtac caggtcgtca aggtcttgca
    10681 gcaaaccaac gcgggcggtg tgtacctggc ccaccgccgg tccgacggtc gtcaggtcgt
    10741 gctcaaggag gcccggccgc acaccggact ggacccggac ggcaccgacg cggtcaccag
    10801 gctcgatcgc gaagcccgga cgctgatccg gctgtcgggt gtgccgggaa cgccggaact
    10861 gcaaggacgg atctcggtgg cgggcaacga agtcctgttg atcagtccga tgcccggggt
    10921 cccgctcagc cgctggctcg cccgcaacta tccactgaca caacgggatc tgaccaaaag
    10981 cgaccgcagc cggtacgtcg aacgcgcact ggcactgttg gccagggtcg aacgcatcct
    11041 ggccgacgtg caccgccgcg gcctggtgta cggcgacctc aacgaccgca acatcatcgt
    11101 cgacgacgac gattcagtgt cccttgtgga cttcgagctg gcgttccccg cggtggaccg
    11161 gcgcaggccc agcggcggca caccgggatt ccgcgcgccc gtggaccgca gcggatacga
    11221 agtcgaccgc tacgccttcg ccgtgctgcg gctgtggatg ttcctgccga tgacgatggt
    11281 gctcgacctc gaaccggaca agctcgccga cttcgtccgc caggtccgca aacggttcga
    11341 cctgccgctg ggctacctcg aggaagtcct cgccgaactg cggccacgct cggcgcgctc
    11401 ggcccgcagg cggaccccgt tggaccagcc ggagatcaac tggacgtcgg tccgcaggtc
    11461 cattgcggac ggtgtgctcg ccagcgcgac gccacaccgt acggatcgcc ttttcccagg
    11521 cgacatccag caattcgcca cgggcggcac gggcttcggc tatggcgccg caggagtgct
    11581 gcacgcgttg gacgtcagcg gtttcggccg gtttcccgcc cacgagaagt ggctgatcga
    11641 cgcggtccgc aggcaacccc ctgccacagc gggattctgg gacggcgcgc acggcacgat
    11701 ccacgtactg gacaacttcg gctaccacga cgacgccgac gagctgatcg aaaaggtcga
    11761 gccgcagctg tcgtcgatca cgtgccacag cctgcgcacc ggactggccg ggatcgggct
    11821 caacctgctg catctcgcgg ccaacaggca ggacgccggg catctgtggc acgcgatcga
    11881 gatcggcggc cggctgaccc acatgctgga gaacgcgccc ctgccgacgc gtggccgcgc
    11941 tgggctgatg cacggctggt ccgggcccgc gctgctgttc ctccggctct tcgaacgcac
    12001 cagggatcgc agctggctcg accacgctga cctggcaata cgccgcgacc tgatggagtg
    12061 cgcgcggaca ccggacggct cattgcaagt ccgggatcgg cagaacacgt tgccgtacct
    12121 ggaagtcggc agtgcgggca tcgcgatcgc gatggaggaa ctgctgaccg cgtggcccgc
    12181 ggcgcccgtg gcgagcgagc tgccgaggct gcgccgggcg ctgctggccg agttcgtgat
    12241 ccagcctggc ctgatgctcg gccgtgccgg tctgatcggc gcgctggcca cgggcttacg
    12301 acgcgaaccg gacccgctcg cgtcacgggc cctggatcag cacctggaat ggctggcact
    12361 gcacgccgtg ccgtaccagg gccatgtcgc cttccccggc acgcatctgt tccggctgtc
    12421 gatggatgtg gccaccggca gcgcgggcgt gctgctggcc ctcgcatccg cgttggacgg
    12481 agtgcagctg ttgccttttc taagtgacaa caccgcactc gcggtgttcg ggctggaaag
    12541 cgtcagtagc ggaagaagtg ttcgcgttgg ccctggcgga cgagcttgag ccactgcacg
    12601 aacgccttgg ggtccttgcg gacggtcagg aagtacaggc cgaaccgcag gacctcgagc
    12661 gcgccgatct tgcgcattcc cgggcgggac aacaggtagc cgcggttgcg gtacgtgtag
    12721 tagcgcttga cgtcgttgtc cgggtcctgt gcgtggaacc ggccgccgag catcggcttg
    12781 aactcgtccg acccgtccgg gtgcaggtac gtcacccgca acgacgtgcc gaacggcagt
    12841 cccgaccgca ccagcctgcg gtgcacctcg acctcgtcac cgcgcacgaa caagcggtag
    12901 tccggcacac cgaccacgtc caaagtggac gcgcggaaca aggcgccgtt gaacagcgag
    12961 gcgatccccg gcaggaagtc cgtgccgagc tcggaggtct ggcgcttcca cgtcaggcca
    13021 cggcgcaacg ggaacgccag cgtctccggg gtgttgatgt tcgcgaccac cggcgagatc
    13081 tccgcgagcc cacgtcgctt ggcctcactc agcaggacct caagcacgtt ctcgtccgcg
    13141 ggcctgccgt cgtcgtcggc cagccacacc cactccgcgc ccatcgcgag cgcgtgcagg
    13201 atgcccagcg cgaaaccgcc cgcgccaccg aggttgcggt gcgacgcgag gtaggtcgac
    13261 ggcaccgcgg ccgcgttcac gaggtcctcg accggctggt ccggtccgtt gtccaccacg
    13321 atcaagtggt ccggcgggcg ggtctgcgcg cccaggatct tcagcgagtc gacgagcagt
    13381 tcacgccggt gccgcgtgac gacgacagcg acgacggagt ccggtcccag cgccttgttc
    13441 atcgaggatc gccacccgcg gtcacaccca ggcgctcgag catctcctgg ctcaggttct
    13501 cgtacggatc tcggcccttg taggcggtca gcacctcacg caggctgccc tgcatcttca
    13561 tccggccgcc gtccatccag atcgccgagt cgcacagctc catcagcaga tcgtccgagt
    13621 gcgacgcgaa caccagcaga ccggagcgct tcaccaggtc ggtcagccgg tcgcgggcct
    13681 tgtccatgaa cgccgcgtcc accgcgccga tgccctcgtc caggatcagg atctccgggt
    13741 cgatcgaggt cacgatgccc agcgccagcc gcacgcgcat accggtcgag tacgcccgca
    13801 gcggcatttg caggaagtcg ccgagctcgc tgaactccgc gatgtcgtcg atcttcgact
    13861 ccatctgctt gcggctcatg cccaggaaca gcccgcggat catgatgttc tcgatcccgg
    13921 agatctccgg gtccatcccg acacccaggt cgaagaccgg ggcgatcttg ccgacgatct
    13981 tcgatccgcc ggtgaccggc tcgtagatgc cggagagcag ccgcagcaga gtggacttgc
    14041 ccgcgccgtt gtggccgacc agtgcgacgc ggtcgccgtc cttgagcgag aggttgatgt
    14101 ccttgagggc ctcgatcacc gggatcttgc tgtcggtgcc gatcgtgccg ccgaccttgc
    14161 ccaacacggc cttcttcagc gaacgggttt tcgcgtcgaa gatcgggaag tcgaccgagg
    14221 cgttccagac gtcgatgctg accatgtgct gtcctgcctc actcagaccc agtaggggac
    14281 gcgcgcacgg tagttgcgca gcgccactag tgccaatgcc cagccgatca gggtgatgcc
    14341 gccgacgatc acccagtggt gccagctctg cgcgctgccg atcagcgggg cgcggatgat
    14401 ttcgacgtag tggtagagcg ggttgagctc gagcaccagg gtcttccaca gctcggtgcc
    14461 cgcaccgagc cggtcgtgca ggatgtcggc cgaccagacg atcggtgtca tgaagaacac
    14521 cagctggatc aaggcgttga tgacctgcgg gatgtcgcgg tagcgggtcg agatgatgcc
    14581 gaacagcagc gccacccaga caccgttcaa cgcgatcagg aagaacgcgg ggatggccag
    14641 caccacggtc cagtcgagac cgggctgcag gatcccaccg gcggtcatct ggtagttcgc
    14701 agtggtcagc gcaccgaaga agatcgcgag tacgacgaag tagaccagca ggttgtgcgc
    14761 catcatcagt gtcaaccgcc acaccgtgcg cagcgcgtag accgtcagcg gcgcgggcag
    14821 gtgcttgatc aggccctcgt tggcgatgaa ggtctcagtg ccttcggtca cgcagccgac
    14881 gatgaagttc cagacgatga agccgactgt cagatacggc aggaacgtcc cgatgttcgc
    14941 cttgaacagc gtggagtaga ggatgccgag accggcggcg gtgaccgcca tgctcatggt
    15001 gatccacagt ggtccgatca ccgagcggcg ataccgctgc ttgatgtcct gccagccgag
    15061 gtggccccac aggtcacgct gcttgatacc gctccggatg tcctcccaag cccggccgaa
    15121 ggtccggctg gggttgtcga gaggcttttc tgccgccgtc atcggtcggt cgatcgtgct
    15181 cgtcgcatgc acggttcccg agagtaccgg cggccattca ccccttcggt gaccggtcgg
    15241 tcaccgggct cacccacacc tgtgctgcgc atgaaaaggc atggtaagtc cgctaggcat
    15301 gcggcagcat ggccgggcat ccgttgcgat atcccgggtc gtattcgaaa tgccatggct
    15361 cgttctcata acgtcggcac cagccatatg agcctgcggt gcgttccagc cagccggccg
    15421 ccgacaacgg ctggacatcg atcgcggtgc ccagttcgtg catcgaccga ccggcaggca
    15481 ggacgtgttt acgggcctcc tcgacgctgc cgtaccgccg gacatagtcg tcgaactggg
    15541 cctgttgctg gcgggagctg cgtttgccgt cgttcaggca caacgtgacg ttctggctgc
    15601 gcgccgcggc cttgatcttc tcgaactcgg gaagcacgtc gtctcgcagc cctttcggct
    15661 gttcgtcgac gtagcgccgg tcggccgggc acggcgggcc gttgtccggc ccgatgacgc
    15721 ctctgatgtc gaatgtggcc tggccgctga ccgtgtcgta gccgatcacc ttcaagctcc
    15781 acagcccgaa aagtgatcca gagaacacca cgacaacccc agctaccagg acggctctaa
    15841 tccatccccg cacctaatga agacgcctgg cgcccccacc gagttgcctt cagaggtatt
    15901 ggccacgtgt cgtgtcgtgc ggctgctgct cacccagacc aggcggcagg gcgccgcggc
    15961 gcatctgctc gagctgcacg cgcgcggaca tctgctgcgc gaacaacgcg gtctgaatac
    16021 ccgcgaaaag accctccaac cagccgacga gctgagcctg cgcgatccgc agctccgcgt
    16081 ccgacgggac gctgtcgtcg gtgaacggca gcgtgaggcg gtccagctcg gcccgcagct
    16141 caggggccag gccctcctcg agctccttga tcgaggaagc gtggatctcc ttgagcctgg
    16201 tgcggctggc ctcgtcgaga ggagcggccc tgacctcctc aagcagctgc ttgatcatgg
    16261 tcccgatccg catcaccttg gcgggctgct cgaccatgtc gccgatcgtc tcgggcttgt
    16321 cgccctcatc cgagccgtcc ggaatgcgcg cggcgcccaa tggggacccg tccggtccca
    16381 ccacgaccac gtggtgtgcg tcgtccttgc cgttctgctc tggctggctc atctgtccca
    16441 tcctgacccg ctcatggaag ccgtcgtgtc ccccgaaaga ccacataccc gagggtagcg
    16501 gtcgcgacac ttggaccggt ccgtacggtg tggcccatgg cgttcgacgt cgctcggatc
    16561 cgtgggctgt tccccgcgtt gggtgacggc tggattcatc tggacgcatc ggccggtatg
    16621 caggtgcctg agcaagtcgc catggcagtg gccacggcga tgcgtgcacc cgtgtccgga
    16681 cctggtggcg ccttcccggc gtcacaacgg gccgaggcca tcgtggacgc cgcccggcgg
    16741 gcggtggccg acctggtcgg gggtgacccc gctggagtgg ttcttggccc gaacgtgccc
    16801 gtactgctgc aacggctggc cgagtcgatg ggcagcggct ggctgatcgg tgacgaggtc
    16861 gcggtgtcga ggctggacca ccaagccaac atcgccccat ggctgcgcgc ggcccaacgg
    16921 ccgggcgcgg cgatcagatg gggcgagatc gacatcgaga cctgcgagct gcccgcgtgg
    16981 cagtacgaga gcctcatgtc ccgccggacg aaggtcgtcg cggtgacggc ggcatccggt
    17041 gccgtcggca caagacccga cgtccgcaag atcgccgaca tcgcgcacag cgtaggcgcg
    17101 ttgctggtgg tcgacgcctc agcggcggcc ccgtacatgc ctatcgacat gaaggccatg
    17161 ggcgcggaca tcatcgccgt gtcggcctcg gcgtggggcg gcccggccgt cggcgcgctc
    17221 gtgttcgccg acccggacct gcttgaccgg ctgccagtga gctccctcga ccccggcacg
    17281 cgtggcccgg aacggctgga gctcggggcg cacgcgtatc cgctgctggc aggcctggtc
    17341 gcctcggtgg actacctggc gatgctggac gacacggcga ccgggacgcg ccgggagcgg
    17401 ctgcagacat cgttgtcatc ggcgaagtcc tacctggccg ggctgctggc gaagctgatc
    17461 tccgagctgc gggcgatccg caacgtgatg gtgatcggcg acgcgatgcg aagaatcccg
    17521 gtactcgcgt tcacaatcgg ggacatgaaa gcctccgacg cgatcgtcgc cctggccgac
    17581 cgggggatct gcgcgttcgc cgacgacgtg cccagcggag tcttcaccgc gcttggcgtg
    17641 agcgaagtgg gcggcgcggt ccgggttgga ctcgcgcact actcgacgtc aagcgaggtc
    17701 gaccagctgg tcgacgcggt cgcggagcta cgccactagg tctccggtgc tcccgctgtg
    17761 gcatggggag caccggagaa acgaggcaaa gggatcaccg gcaaatccgg ttgtccacaa
    17821 ccaaccagta cccctttgac ctgcccatat ccccggtaga ctggccaggg gtcgtccccc
    17881 cgggagtggt gggggatgcc ctttttctgg ggtgggatgt ccttttctgg ggtgggcccg
    17941 gctcgtcgtt acggcttgag gatgattttt ccgaagacct cgccgccgct ttccagcgcc
    18001 gcgtgtgccc cggaagcgtc ctgcatcggc cggacctcgt gcacgatcgg cttcaccttg
    18061 ccctcggcga tcagcggcca cagaccttcg cggacgcccg cgaccacctc gcccttgctc
    18121 ccgcggccgc tcaccgggcg gccacgaagg ccaagggagg taacgcttgc ccgcttcggc
    18181 agcatcttcg agaagtccag ctcggccttc cgtccacctt ggaatccgat caccatcagc
    18241 ctgccgtcgt tcgccagcgc ggtgaggttt ctgtccaaat aggacgctcc catgttgtcg
    18301 aggatcacgt cggcgccgcg ctttccgagc acctcgacga agtcctgggt cttgtagttg
    18361 atcgtgatgt ccgcgccgag cgaggcgcag cgctccagcc gctcatccga gcccgcggtc
    18421 accgccaccg tcgcgccgag ggctttgccg acctggatgg cgtgcgtgcc gatgccgccc
    18481 gcgccgccgt ggatgagcag gatctcaccg gattgcaggc ctgcgtgctg aacgatgttc
    18541 gaccacaccg tgcacgcgac ctcgggcagt gaggccgcgg tgaccaggtc gacgccgtcg
    18601 ggcagcggga gaacctgtgt ggcggggacg gcgacgcgtt ggccgtaacc gccgcctgcc
    18661 agcaacgcgc agacttcgtc gccgacttcc cagttcgtca cgccttcgcc cagcgcggcg
    18721 atggtgccgg agcactcgag tccgatgatg ttcggggcgc ccggcggtgg cgggtagaag
    18781 ccttggcgtt gcagcaggtc cgcgcggttc accgcgctcg ccgcgatatc gatcagcacc
    18841 tcgcccggcc ctgcctgggg gtccggcacc tcggtccatt ccagtacgtc aggtccaccc
    18901 ggctcgcggg ccacgattgc atacacatca ccacggtaaa cctctcgcgc cggtgaatac
    18961 gctcggggca tggatccctg gcccttgcga aacctcgtta tccggactcc gcgcctcgaa
    19021 ctgcgcccgg acgacgacgc ggggctgttc gaactcgtcg aggtggccaa ggccggggtg
    19081 cacgcgcccg acaagatgcc gttcggggtg ccgtggacag atcggccgcc gatcgaatgg
    19141 gtcaagttct actgggggca acgggccgcg ttctcgccgg acgactggag cctcaacttt
    19201 ctgaccagag tggacggccg ggtcgtcgga atgcagggag cggtcgccaa ggatttcgct
    19261 gtcacacgtg agatccacac cggttcgtgg cttggcctcg cccatcaggg caaggggtac
    19321 ggcaccgaaa tgcgtgccgc cgtggtcatg ttcgcgttcg actacctcgg cgccgagcgg
    19381 atgacatcgg ccgcgcacag tgacaaccgg gcttcacaca ccgtgagcag gaagctcggt
    19441 tatcgccccg acggcgtgga aaggcagtcg atcaaaggaa aactggtctt caacgagcgg
    19501 ctcgcgctca ccccggagca gttcgtccgt ccggaatggt cgattgaggt cgatggtctg
    19561 gacggctgcc gcagcttgct cgtttcggag cctttgggcc gcatgtaact cttgaccggc
    19621 gtgcagcgcg gagagaggtt gacggcccat catgcaggaa ctacgacggt gacgactccg
    19681 acggcgtggg ctccggccct ggaccgaccg gatcgggccc gatcgaggca gcgctggcgg
    19741 cgcgattcgc ggccgcgccg accgaaggca aggacttcga cggtcgttcg gactacggcg
    19801 agttcatcgc gcagggcatt cccgctggtg gcacgttcac cggcgccgaa gtgatcaaga
    19861 ctgccgagca ggccgcgaag tggggcggcc aggccggggt ggcctttgac aagtgctacc
    19921 accaagcctg cgacaatctg ttcaacgtca accgggcggc gcttgccaag caggccgccg
    19981 cgatctcgta cgtgatcacc gcgtacggga tcagcacgga ggacgtgaac ggcgtgccgc
    20041 cgcgttccga gcgggcgcag gctcgcgccg ttgccaagac cgtgtcggtc tcggcaacgc
    20101 atgaccacga cgcggtcagc tagtagccgg gaccgaaatg gggcgccccc gccgaggcgc
    20161 cccatttcgc ttgtctctga cccctcacgg gttttcagcc caggttgttc gtgcggaacg
    20221 tgtcgcactg ggccgggttg ccggactgga tgccggtggt gaaccacttc tcccgctgct
    20281 gggaggtgcc gtgggtgaac tggctctcgt cgacccggcc gccgcccagc tcacgctgga
    20341 tgaagtcgtc gccgatccgg ccagcggcgt cgagtgcgcg ccggatgtcg tcctcggtga
    20401 tgttcctgat cagcggggga ccaccgttgg cgctgggcgt ggtcgtcgcg tggttcgccc
    20461 agacgcccgc gtagcagtcc gcctgcagtt cgagccgcac cgcgtcggac gtgggcccac
    20521 gcctcgtccg cacccgatcg gatgtaccga gcaggttctg cacgtgatgg ccgtattcgt
    20581 gcgccaggac gtaagcctcg acgaacgtgc cgccctgcgc accgaactgg ctctgcagct
    20641 gggtgaagaa cgacaggtcg atgtagacct cggaatcggc gggacagtag aacgggccga
    20701 cgtcagcggt cgcgctgccg caccctgtgg tcacaccgcc cctgaagaaa ttggtgggcg
    20761 cctgctggta cgtctgaccg gagcgcgcga actggtcacg ccagtagccc tggatcgagt
    20821 tgatcaccgc gaccagcgca cagtcatggt tggtgttggc gtcgcgcccg gtgcggcact
    20881 gctcggagat ccgcgcgttg tccacgcgct ggcccgacgt gacgtcgccg agtccgctcg
    20941 ccgagttgcc gtccagcccg gcgaccccgc cgaactggga catgacgaag tagatgatca
    21001 agccgacaat gctgagcccg ccgccgccca gcagcacacg gccaccgaca ccgccgccgg
    21061 atgaccgcat gtcctcgact tgagaggtgt ccaaacccgc gtcgtcgttg aattccacgt
    21121 cgcctccgtg gtgtgtggaa gccaacgata taaggccggg tgcggcgtgc tctgaaacgc
    21181 cgcacccgga tcggatggac ttgtctggcc gcagccgccc tcgcccgact ggcgcggagt
    21241 ccagagcggg gactcaacgc gtcgacgtgc gatgcacata ccgatcaggc tggacccgcc
    21301 gctcgcaatc gcgaccgcgc cgatgctttc agctcagccg cggggatgcg gcagggagcg
    21361 cgcgaccatt cgccttaagc gcattgccac ggcaccacct gcccttcacg ttcggagtaa
    21421 cgtctggttc gagcatgcac ctttgtgtcc cgcgtcacaa gggacctgaa ttggtgaagt
    21481 tccggtaact gtccgaacag gacgttttta tctcgatatc gagcgaactg gcagaatttt
    21541 cggcgtgggc gacaccgtgg acaagatcat tcagcagtgg cggcatgaaa gaccggagct
    21601 ggacctggca ccgatggccg tgactgcccg tctcacccgc ctggcggcac tgctggaacg
    21661 cggcgtggac gacaccctcg cggcccaagg actggccagc tgggagttcg aagtgctggc
    21721 atcgttgcgc cgcaacggat cccccttcgt cctgtcggta ggacgcctgc aagccaccat
    21781 gatgatcagc tcaggcacga tgacccaccg cctcgaccgc ctggaaaagc gcggcctggt
    21841 cgcccgctcg aaagacctga acgaccgccg cggcatccag gtctccctga ccccagacgg
    21901 ccgaaccctg atcgacaacg tcatcgaagc ccgcctggcc cgcgaacgcg acctgctcac
    21961 caccctcgac aaggaccagc aaaccaacct cgcgtccctg ctcagaggcc tgctcaccgc
    22021 aatggagcaa tgagctgacg gggcaggctg tccgcggacg cacggcgggg agccgggggt
    22081 ctgggggccg tgcccccaga agacacctaa cgcgacgtgg tccgcgctgt ccgagacatg
    22141 tcggcgagcg aagctcgcct tcggggggtt tgggggtcgt ccccccaaaa ttatggcggg
    22201 cgacccggtc tgcctttttc cggcagacat ggatcgcccg agcccgcggt agcggtggga
    22261 ttcgaaccca cggagggcgt gaaccctctc atgttttcaa gacatgttcc ttcggccgct
    22321 cggacacgct accgccgatg agcctagccg atcgccgtgt gtggattcag gtctggtcga
    22381 ggtgggtgag cacgcgctcg aacaccgtcg ccagcactgc gcgctcctct gggctgatca
    22441 ggtcgatgag gtggtcgcgg acgccttcga cgtgggttgg ggccgcggtg cgcagttgtt
    22501 ccatgccttt ttcggtgatc tcggcgagta cgccgcgggc gtcgttgggg cagtgggtgc
    22561 ggcggaccag gccggcggct tcgaggcgg
//
