LOCUS       NZ_FWXV01000001        22781 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000001
VERSION     NZ_FWXV01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 744629
            Orig. end                         :: 767410
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22781
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22781
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22781
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12781](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12781)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(310..735)
                     /locus_tag="B9C43_RS02955"
                     /old_locus_tag="SAMN05661093_00612"
     CDS             complement(310..735)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-140). E-value:
                     5.3e-13. Score: 41.5. Matches aSDomain:
                     nrpspksdomains_B9C43_RS02955_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022072.5"
                     /locus_tag="B9C43_RS02955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00612"
                     /product="SRPBCC family protein"
                     /protein_id="WP_084424461.1"
                     /transl_table=11
                     /translation="MVSDTIQRDITISASIDKVWAALTEEKHIKEWFGDEAEVDLRPGG
                     AIVFGWAPHGRFHGKVAAVEPPHRFSYWWARPADTDPAPGNQTLVEFTLSEDGDGTRLR
                     VIESGFTALSGDQELAVKENTEGWHRELDELRAYVEA"
     aSDomain        complement(316..723)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS02955_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.30E-13"
                     /label="B9C43_RS02955_Polyketide_cyc2.1"
                     /locus_tag="B9C43_RS02955"
                     /protein_end="140"
                     /protein_start="4"
                     /score="41.5"
                     /tool="antismash"
                     /translation="TIQRDITISASIDKVWAALTEEKHIKEWFGDEAEVDLRPGGAIVF
                     GWAPHGRFHGKVAAVEPPHRFSYWWARPADTDPAPGNQTLVEFTLSEDGDGTRLRVIES
                     GFTALSGDQELAVKENTEGWHRELDELRAYVE"
     gene            843..1451
                     /locus_tag="B9C43_RS02960"
                     /old_locus_tag="SAMN05661093_00613"
     CDS             843..1451
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005455162.1"
                     /locus_tag="B9C43_RS02960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00613"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_084424462.1"
                     /transl_table=11
                     /translation="MSGLRERKKIATREALSAAALRLALERGPENVRVDDIAEAAGVSP
                     RTYNNYFSSREQAIVAAIGAERAHGIADALLARPAEESLAEAVVAAIAEQYTSEPAGDA
                     LTLITTAPALREEYVKTVLSIESPLASAIAARTGVDDELATAVLAAAISAAARVAVERW
                     ITRTESGLVVVPAIPLADLLRNALFHLAPAMDALVSRER"
     gene            1584..2069
                     /locus_tag="B9C43_RS02965"
                     /old_locus_tag="SAMN05661093_00614"
     CDS             1584..2069
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="B9C43_RS02965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00614"
                     /product="response regulator transcription factor"
                     /protein_id="WP_051894694.1"
                     /transl_table=11
                     /translation="MDNEVFRSFNAVPGVCAAQVDARGVVVKASQQLYRRLGCHPDDLR
                     GRYFMDVVRRDGLRGETIIVMVESEQERRPETTGGGTKKILTKMDSRILEGVAAGVSTA
                     KLAVMVDLSRGGVEYHVTNLLRKLRAPNRTSLVSKAYAEGILEAGTWPPKVVPDFVK"
     gene            2081..2599
                     /locus_tag="B9C43_RS02970"
                     /old_locus_tag="SAMN05661093_00615"
     CDS             2081..2599
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559890.1"
                     /locus_tag="B9C43_RS02970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00615"
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="WP_084424463.1"
                     /transl_table=11
                     /translation="MPLFSFEGKSPQVHPSAWIAPTATLVGDVIVEAGASVWYGAVIRA
                     DFGRIVIREGANVQDNAVIHVGPNGCSVGRGATVGHLCLVHDCVIGDYAIVGNGSTVLD
                     GSRVGERAMIAAGSTVTPASEVPAEVMAMGSPAKRHIPLTDSAREWIDTNPSLYQELAR
                     RHAAGIAEV"
     gene            complement(2603..3472)
                     /locus_tag="B9C43_RS02975"
                     /old_locus_tag="SAMN05661093_00616"
     CDS             complement(2603..3472)
                     /NRPS_PKS="Domain: Abhydrolase_1 (29-162). E-value: 7e-11.
                     Score: 34.1. Matches aSDomain:
                     nrpspksdomains_B9C43_RS02975_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010240879.1"
                     /locus_tag="B9C43_RS02975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00616"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_200825408.1"
                     /sec_met_domain="PF00561 (E-value: 1.9e-08, bitscore: 31.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-09, bitscore:
                     34.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTTHILETAEVDLAYDLHGPLPTADGRPLLFMIGQPMDATGFTR
                     LASYFPDRTVVTYDPRGLGRSNRKDGRVDSRPEVQAGDLHALVEALGAGPVEVFASSGG
                     AVTALAWVAAYPSDVVTLVAHEPPLIHVLPDAPAAERALNGYLEAYQAKGFGAGMATFI
                     GMTAWKGEFTDEYFAQPPADPAQFGMPTEDDGKRDDPLLSDRAIAIVQYRPDVEALTTA
                     STRVVIAVGEESKDVFTGRTAVATAELLGQEVTVFPSHHGGFLGEEFGYAGQPEAFAAK
                     LREVLDKG"
     aSDomain        complement(2987..3385)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS02975_Abhydrolase_1.1"
                     /evalue="7.00E-11"
                     /label="B9C43_RS02975_Abhydrolase_1.1"
                     /locus_tag="B9C43_RS02975"
                     /protein_end="162"
                     /protein_start="29"
                     /score="34.1"
                     /tool="antismash"
                     /translation="LLFMIGQPMDATGFTRLASYFPDRTVVTYDPRGLGRSNRKDGRVD
                     SRPEVQAGDLHALVEALGAGPVEVFASSGGAVTALAWVAAYPSDVVTLVAHEPPLIHVL
                     PDAPAAERALNGYLEAYQAKGFGAGMATF"
     misc_feature    complement(3460..3480)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.57"
                     /tool="antismash"
     gene            complement(3524..4747)
                     /locus_tag="B9C43_RS02980"
                     /old_locus_tag="SAMN05661093_00617"
     CDS             complement(3524..4747)
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021134.5"
                     /locus_tag="B9C43_RS02980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00617"
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="WP_084424464.1"
                     /transl_table=11
                     /translation="MSLLRAVGRPTALGVVVVTALNLFALLWMLTARTPGGGLSFDVYR
                     IDIDAYRIGLKVWWDGGDLYGRMPETQVGISLPFLYPPFAAAFLAPLGILPFGVASALW
                     TLLTIALVALVIVLVLRSIGASNPWWLTAALLPFALFIEPVRDHIFFGQVNIFLMALVV
                     LDLLVKSPRWPRGLLIGLAAAIKLTPLAFLLFLLLRRDFRAAVTAVLSFVAFGVIGALI
                     SWENSVKFWTGAMFGSDRVGAGYAGNQSILAVLLRLGGEPPLRSVVWIGLCAVVLVLGI
                     FAMRTVLADGKVALAMGINALIMLLVSPISWSHHWVWCVPLLLALAWHSKVLAAAGLVV
                     FSLSAHWWWPNTVNREQGWDALQQIAGSSYPIFAVAVLVVLAIRVSKQNASLSLSGRSN
                     SPELSGLD"
     gene            complement(4944..5606)
                     /locus_tag="B9C43_RS02985"
                     /old_locus_tag="SAMN05661093_00618"
     CDS             complement(4944..5606)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013777.5"
                     /locus_tag="B9C43_RS02985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00618"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_033379865.1"
                     /transl_table=11
                     /translation="MRTYAQYCPIVRAVELLGDRWTLLIVRDMLIGSTRFNELARGLPG
                     ISRALLAQRLRQLHKAGLVTRTDDGYALTKAGTDLRPIVFSLGEWGARYAFGDPQPYEL
                     DPEVLMWWMHGRIDTSELVKRAVIQIDVTDRRRQFWLVLEPGDASICYTDPGFDIDAVL
                     SADLPTLYRMWEGEIELLDAVKAGSIGLTGARWVIRSLPTWLMLSPVAATVRAVRGS"
     CDS             5618..5695
                     /gene="allorf_0750247_0750324"
                     /locus_tag="allorf_0750247_0750324"
                     /protein_id="allorf_0750247_0750324"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTRHDIRYAGFSFRTTCAPRTFLPS"
     CDS_motif       5618..5644
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTRHDIRYA"
                     /locus_tag="allorf_0750247_0750324_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5645..5695
                     /prepeptide="core"
                     /locus_tag="allorf_0750247_0750324_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="1697.9"
                     /monoisotopic_mass="1696.9"
                     /core_sequence="GFSFRTTCAPRTFLPS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTRHDIRYA"
                     /leader_location="[5617:5644](+)"
                     /alternative_weights="1716.0"
                     /alternative_weights="1734.0"
                     /alternative_weights="1752.0"
                     /alternative_weights="1770.0"
     gene            5699..6856
                     /locus_tag="B9C43_RS02990"
                     /old_locus_tag="SAMN05661093_00619"
     CDS             5699..6856
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) azdH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019640.5"
                     /locus_tag="B9C43_RS02990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00619"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_084424465.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.8e-10, bitscore:
                     36.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="azdH (E-value: 3.6e-22, bitscore: 75.4,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8e-14, bitscore:
                     48.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.3e-06, bitscore:
                     25.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTMTLQTGTYPTPVRPDDTRFVDLAARVGAIAAEHAASHDRDAT
                     FVAEAYAAMQEYGYLALAVPAELGGLGATIRQVCYAQAELARHDGATALSAAMHNYLTL
                     MQCYRRRMGAGDAETVLRKVAEGMVIATSGGSDWLWPTTVAIPTDDGYRVTGRKAFCSQ
                     APRANVVSTSAVLPDQSEVLHFSVPLDAPGVRIEETWDTVGMRGTASHDVVLEDVLVPS
                     GKIVGRRAYGEFGVPLLAATVHFAPVVGATYFGIAAGARDLAVSKVSVDRRAAQVHRQV
                     GLMDAKLRGAWWALMGSLDELGTEYTVNPETLTTVMLAKRQAVVEAVEVVNLAMDLLGG
                     RSFFRRAGLERAFRDVRAGTFHPLNPEVTLSYAGKVALGDTGVTE"
     misc_feature    5900..5902
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5909..5911
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6846..8165)
                     /locus_tag="B9C43_RS02995"
                     /old_locus_tag="SAMN05661093_00620"
     CDS             complement(6846..8165)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.5"
                     /locus_tag="B9C43_RS02995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00620"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_084424466.1"
                     /transl_table=11
                     /translation="MLDLVLPDDPRYSLSRNQFIGTRDEVLPQAVARCATPDDVLEALD
                     LAADRDWPFAIRGGGHSNAGYSSSTGLVIDLSPASAVTVSGREVTVGAGLRTGQLAELL
                     SPLELLVPAGSCPSVGLIGAALGGGFGSHGRTHGLTCDHLVSAKVVLASGKVVTASAES
                     EPDLFWALRGAGGGNFGVVTSATFSAVTSTRRTHFRFSWDLSASLVHAWQEWAPFAPNT
                     TSAELILLSPDYAEDPPQMLLIGAGDPTALLTQLPKPNLAEVRHLSAAEAALLHATPYS
                     AAAHDPSSIPLIHSRPGMSTAKTAFFTQPLPSSAIDALLAHFVAARVPGEMREVAFTPW
                     GGAYRSTVDTAFPHRNPSFLVKHTVLVGPNGAARRGHEALAWLTASWKTLEGTGAYPNF
                     PDPSLPDWLTAYYGPNVPRLREVKAAYDPGNLFQFGQSIR"
     gene            complement(8158..10008)
                     /locus_tag="B9C43_RS55375"
                     /old_locus_tag="SAMN05661093_00621"
     CDS             complement(8158..10008)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101533.1"
                     /locus_tag="B9C43_RS55375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00621"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_143446062.1"
                     /transl_table=11
                     /translation="MSDDPRELNTPHWQIDEKAEGPRRVIRSLPRVTWPVLRMIWDAAP
                     RSALLIAIMQVTSGLAAAFGLFATAEVLTELFSSGPTADRVVAALPSLLFVGGAYALRG
                     AMDIGVAIAHARITPAVRRLAEERLYQASLSVELAAFDDAQFYDRMHRARDRGLFYIER
                     STDNLVELIGSVLGIAAAVSSLAVLHPVLLPVLLLAVIPDAWAVQRSAMLAYASMARAV
                     TLDRRVQMVAELATEREPAAEIRACQAEPFVMHEYRVVADPLRDEDIRRGVAQARVRGV
                     GRALAGVGLAVTYVVLGLLVHASWVPLAVAGTAVIAIRASTTALNRLVLASNQLVEQGM
                     YVADYLAFLDSAQRPPVALPAVVADPSRVQLSNVSFTYPTSPQAALRDVSMTIERGQTI
                     ALVGENGSGKTTLAKLIAGLYTPSSGLVCWDGTDVHSLDRASIANRVMMVLQDPIRWPH
                     TARANVQAGRHDRDDPVALVAAAAQSGADEVVDRLPSGWSTLLSKQFRGGQELSGGQWQ
                     RLAVARGLFRDAPLLIWDEPTAPLDAKAEFAVYESLRALAEERTVVLITHRLASVRHAD
                     RIYLLHEGELVEQGTHTELMALGGRYAELHDLQAKMYADA"
     misc_feature    complement(9433..9435)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12781)
                     /gene="lanM"
                     /locus_tag="B9C43_RS55380"
                     /old_locus_tag="SAMN05661093_00622"
     CDS             complement(10001..12781)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="B9C43_RS55380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00622"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_200825409.1"
                     /sec_met_domain="DUF4135 (E-value: 5.1e-74, bitscore:
                     246.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-31, bitscore:
                     106.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPDEVGELDRTVEWLIGPALHRLDGRLAGLAGLVAAEVGAFVDA
                     TREVLLDSVRRKVNRVIVLELNAARVTGKLTAPDPAGRWREFLRTATEPAFWHGLTEHY
                     PHLLERLQAVVDNRCAAVLAMATRFADDRPKLGSLLGNDVGELLKIEIGAGDSHRGGHT
                     VSLMHCAGGTVVYKPRPMQVDAQLAGLLEVLDPQGIRVPRAIVMDGYGWAEHVAHRYCD
                     SDSELSTFYRNLGHWLAVMRLVSGTDLHAENIIACGPIPVVVDCESIFTPRPPHPPTGA
                     GEATDRAAELLNGTVMRTGLLPGRGAGLGWRGVDGSAMGMLPGQQPDIGLPDLVGAGTD
                     TAKIAITPQQLPPTQNLPSRNPQLGRYWGEVVAGFDAMASRINALDRSGELEPLLQRFS
                     DCVVRVVVRDSEAYTELARMLWHPVGLHNQPAAEQKALALIARHSMNTRGPAEQAVHAA
                     EVAELLIGDIPVFTTTPAEGWLHTPAGTVCGPRQDQIQLCLQRWREADFALERRVTHAA
                     LVSAYLNQGAEPDLRQMDTSVEESDVDARRRALAAAEIRTLASEAVRGSDGTVTWFAPI
                     LDRSGWQTTPLTPDLYSGTLGVAVLLDGYAQEVAAGRADLVPEADGLLDGVIQTARRTQ
                     HWWAEQATHTKRRPDPPGGYIGLGSQIWCWLTLGHVEDALFLAAQLPAAIEASEGPDLV
                     VGSAGSIVPLLMLAQRTGDDQWTDLAVQVGDHLAATVLRPAPGQVCWSVANFPDGIGGF
                     AHGSTGIGWALARLSLATGEARFATLADEAAAFEETWYSTERGGWLDPREPTSTVAAWC
                     HGALGVGLAAADLLGRGFAPDRNHDVLRRAVAATEEGGFGWTHTLCHGDMGSWELLGAS
                     RTAQIITSLETHGTTTGLAREVYSPSLMSGSGGVAYQLLRMHPECTLPSVLVPGE"
     misc_feature    complement(10586..10588)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12791..12979)
                     /locus_tag="B9C43_RS03005"
                     /old_locus_tag="SAMN05661093_00623"
     CDS             complement(12791..12979)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF040361.4"
                     /locus_tag="B9C43_RS03005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00623"
                     /product="DUF6229 family protein"
                     /protein_id="WP_037270310.1"
                     /transl_table=11
                     /translation="MTAAMLADAEELVARWREGLDLDSPAGPIFASGEFAEGDIVACNP
                     PGSRCSSCTASRPVFCC"
     CDS_motif       complement(12899..12979)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTAAMLADAEELVARWREGLDLDSPAG"
                     /locus_tag="B9C43_RS03005_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12791..12898)
                     /prepeptide="core"
                     /locus_tag="B9C43_RS03005_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="3471.9"
                     /monoisotopic_mass="3469.6"
                     /core_sequence="PIFASGEFAEGDIVACNPPGSRCSSCTASRPVFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTAAMLADAEELVARWREGLDLDSPAG"
                     /leader_location="[12898:12979](-)"
                     /alternative_weights="3489.9"
     gene            complement(13067..13819)
                     /locus_tag="B9C43_RS03010"
                     /old_locus_tag="SAMN05661093_00624"
     CDS             complement(13067..13819)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.5"
                     /locus_tag="B9C43_RS03010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00624"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_084424467.1"
                     /transl_table=11
                     /translation="MRVRLARGRLMEIMVLGRPMVHIGGNGLRPLRRMARVLLGLFALR
                     PNRPLSLEWLINGLWPTKPPASAAANVRSHIAELRRLLAGGDKPSIETLDDGYMLVTAP
                     HGVDALLFRELVAQARKHTGLDAARLLTQAVGLWRGDVLEGVPIPAALEAEAAMLEDLR
                     MSATEELVEVRMSLGHEQDLVPILKGLVIEHPLRERLWHQLLLALWSTGRRSEVLEEYQ
                     RLWSLLDRELGVRPAQATTELNELARRG"
     misc_feature    complement(13736..13738)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13779..13792)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     CDS             complement(13888..14064)
                     /gene="allorf_0758517_0758693"
                     /locus_tag="allorf_0758517_0758693"
                     /protein_id="allorf_0758517_0758693"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MARRFIHHPAGRRRRRSGGDFEYPGACTCRAFSGGRAVHNYGQPG
                     CRYAELDDRTSAH"
     CDS_motif       complement(13987..14064)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MARRFIHHPAGRRRRRSGGDFEYPGA"
                     /locus_tag="allorf_0758517_0758693_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13888..13986)
                     /prepeptide="core"
                     /locus_tag="allorf_0758517_0758693_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="3427.7"
                     /monoisotopic_mass="3425.6"
                     /core_sequence="CTCRAFSGGRAVHNYGQPGCRYAELDDRTSAH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MARRFIHHPAGRRRRRSGGDFEYPGA"
                     /leader_location="[13986:14064](-)"
                     /alternative_weights="3445.7"
     gene            14205..15107
                     /locus_tag="B9C43_RS03015"
                     /old_locus_tag="SAMN05661093_00625"
     CDS             14205..15107
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024776.5"
                     /locus_tag="B9C43_RS03015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00625"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_084424468.1"
                     /transl_table=11
                     /translation="MQPLQALGISADAERVYLDLVEHGTTGVEPEHKAVAELEAAGLVE
                     RSGGTLVACPPQLAMEALAERYTALARQSAAMLARVWNKTNDTYLEVLPSYSAGRAVLD
                     RVQTDARTRVRALSVGNLGPDGHKIVEGLFDALARGVAYQVIYGTHVLRDPEALRMVQR
                     CVDAGEQARVFPHVSMNLTIVDDRWALLTARSDEDIAAVVVHRSPLLTGFVGIFDAYWR
                     MAVPITAGTETAPAGDTPSRDTQRLLTYLSAGLTDEAIAREFGVSERTVARRISRLQEI
                     LGAQTRFQLGVQASRHGWL"
     misc_feature    14481..14483
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15028..15570)
                     /locus_tag="B9C43_RS03020"
                     /old_locus_tag="SAMN05661093_00626"
     CDS             complement(15028..15570)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS03020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_00626"
                     /product="hypothetical protein"
                     /protein_id="WP_143446064.1"
                     /transl_table=11
                     /translation="MNGLTMGMVMWIVWLIARPGFAWGPVIVSAGSGLGAALGSLSVRK
                     QMLAAFPPMTLLEEKIKAWRIVRDGGPVDNAADVRIVARYAQWILRRPSAVTVFLAWFA
                     SIAITLGLSLLIIDVDPEYARVCAIATVLCLAYFPIILRIPKQRENAERALTASRAVMP
                     APPTGSESAPPGSPAGG"
     gene            complement(15638..16174)
                     /locus_tag="B9C43_RS03025"
                     /old_locus_tag="SAMN05661093_00627"
     CDS             complement(15638..16174)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS03025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_00627"
                     /product="hypothetical protein"
                     /protein_id="WP_084424470.1"
                     /transl_table=11
                     /translation="MAERWARLRFGSPGLFTLLTASIGAGVVWVSWVVGYFSFELRHVF
                     FAAFSGLCFAAASAFGRSQAPPPFPPGLHLDDTMRIWRLVRYGGPVENKADVSAVNHHA
                     RWLLSGPSTSALATGLAVAISVAAVVIIVAPKDDPFYVRVPALYLVVFAAMIPMTMRRA
                     KWLWNAERVLEVPKR"
     misc_feature    16301..16318
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     gene            16367..17755
                     /locus_tag="B9C43_RS03030"
                     /old_locus_tag="SAMN05661093_00628"
     CDS             16367..17755
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015531.5"
                     /locus_tag="B9C43_RS03030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00628"
                     /product="S41 family peptidase"
                     /protein_id="WP_143446066.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 4.3e-24, bitscore:
                     81.8, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSLKLFAIITAVAAVASTATVSASPEAGKPSTCRTPPQEPPPLT
                     PTTVTTIGQAYYCIFDNYFSGPVLDSRDLLQPAFAAFTRELQRRGLDQANASAPVLTGK
                     RDADWRAFSKAYQDIVAKLPADVHQAVAEVTITAMVDSLNDNHARWMRPTESDSVPVGF
                     LPSHARGPGRTDPTTSGPAFVVDLLPGSAAANAGIKLGDEILTVNDVPLFINGVAVPGV
                     VEWLMEAKEGQQVKLTMRRPSTGETKTYTLTVTKPSGPPPQREVVESKLLPGDVAYVSM
                     RGFARDAADKVLKAIADLGKDRTLRGVVLDLRGNGGGSPDEVKKLVSSWVHGKTYSYWC
                     DVKDKCTPNRTDDSVPLVNLPLITLTDRRCASACDAFSSAAKVLKFGTLVGQRTAGAVS
                     GPGDGWVLDDGSMIGLPKIHEIGPDRAKVDTVGVPPDHFAPITAADLSAGRDPGVAKAL
                     ALLK"
     misc_feature    16376..16378
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16589..16591
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17797..18450
                     /locus_tag="B9C43_RS03035"
                     /old_locus_tag="SAMN05661093_00629"
     CDS             17797..18450
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153517.1"
                     /locus_tag="B9C43_RS03035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00629"
                     /product="response regulator transcription factor"
                     /protein_id="WP_084424472.1"
                     /transl_table=11
                     /translation="MRVLVAEDERDLADLVATGLRRHAMAVDVAYDGTAASERLAVNDY
                     DVLVLDRDLPEVHGDKICQDLVRSGARTRILMLTAAASVPERVAGLGLGADDYLPKPFD
                     YSELVARVQALGRRSQAPVPPTLRRHGIEMDTQRMQVMRDGRFLRLSLKEFAVLEVLMR
                     ANGAVVSSERLLESAWDEHTDPFTTVVRVIISRLRAKLGDPPCIQTVPGAGYVL"
     gene            18447..19559
                     /locus_tag="B9C43_RS03040"
                     /old_locus_tag="SAMN05661093_00630"
     CDS             18447..19559
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="B9C43_RS03040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00630"
                     /product="ATP-binding protein"
                     /protein_id="WP_235038404.1"
                     /transl_table=11
                     /translation="MRRRTMRGRLTALYTGIFLVTSTILVIVVNSVFSDRLHAQVAQIT
                     PGGRPVARPVLPPIPPGPFADVENLPDEVLRDQWTATVITIVVLTLLSIIAGWWMAGRM
                     LRPLRRITATAQRLSLSNLDERIALTGRNDELKELADTFDAMLERLERSVDSQRRFIAN
                     AAHELRTPLATQRAAIQIGLEDAEDLPEVRAKLLTHNQRTEQLIDSLLVLAEADHGLDA
                     PQPVDLAALVRQTAAESTSEAIAMTVSTEPLVIRGDPVLLHRLLVNLVSNAVRYNHPGG
                     SVHIGLTALGLLTVRNTGPHVPADRIPELFQPFRRLHTRTRHDGAGLGLSIAASIARAH
                     HARITARPNDDGGLSLTVEFGIPTTVPVSR"
     gene            19643..22204
                     /locus_tag="B9C43_RS03045"
                     /old_locus_tag="SAMN05661093_00631"
     CDS             19643..22204
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226933.1"
                     /locus_tag="B9C43_RS03045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_00631"
                     /product="glycosyltransferase"
                     /protein_id="WP_084424474.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.5e-08,
                     bitscore: 31.4, seeds: 63, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.3e-26,
                     bitscore: 89.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLWGISFDATPISGVVVEFVKTAKHFADRGVPVVLDLGYDIKA
                     DKDAFFRPYQDEAQLLPEWVRLGRIAGVEQIPGYDRDFVAEVLREVVGRGEGTHLLPRI
                     DSIAERLSDLIVAAWEANDIEYVLVENGTLPENITYTKALHLAIEKYGRNRGRYVLWRD
                     HDLMWQSEPSSGKYGVYPYPATPKPPNSPHIHYLALHDQARRKTLEWAPHLRAIDVLPN
                     TFTHRKATIHTGNADFRSDYGIPARAPLIARCTRIIRQKRIDRDLHLLAGIPDAVLFVA
                     GDTTESPDEYRRLVALARQLGVTDRVVFGGWLAPHEDDIGRSTGCKYSVRDLLAHADLV
                     SFLTSFDYESYGNPVGEAIASGVPYVTTRYELYDTVYGSKGFRAPLLTDDLPDEDFIGQ
                     VRDLLTDEEERAEMAEHNFRLGERDFGTARDLLDRLVLVPMDEQVRLSVILPVYNEAAN
                     LPAVLDSLYHQRGLDRSTYEVVLVDNNSTDNTAEIAKTFAAEHPDLAVHVIPEPEQGVS
                     CARRTGMQFASVRSRGRVNAEERFYLVSADADCRVDEDWLYELFVAMESGKAAIGVCDY
                     YYSAEHFAGRPRLWDAITKTLRCRAVTFALFGGFPDGKGFAVDRDVHDRVGGIEIFYQL
                     QDGRFVNHLSDDWDFGIKVRGSGEDIGYVPRSRVEINPRRVDHAIDEVIAGRAYGSDGI
                     IVMRDIRPQAEGTGADLTEEQARQAWDFSVKDFTPKNTILPVLLTPSLLDDDAVIEFFG
                     PSLAERLGRRIAEIKDEMRMTDFTPIHSYKTPSYRLYFEFADEIFARLRATVGDDIGYP
                     PPLPPCLQDVSPDRFTEFVKYYCEDRESGEAHNYFGNGGVF"
     misc_feature    20543..20545
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cttgatggtc cgcagtcgac ggtcccattc gtcggcgagg cccgccatcc aggtcgcggt
       61 cgaggccaac cgatcggatt tgaccgaata gcgcacctca cggccgtgcc gcccgccgtc
      121 gaccaggcct gcctgctgca gcacggacag gtgtttgacg atcgcttgcc tggtcaccgg
      181 gacgtcggtg gccagtgtgg tcgcagtggc ctcgccgcgg gtggcgaggg cgtccagcag
      241 gcgtcgacgg gtcggatccg ctagcgccgc cagcacctcg tcgacaccgt tggtcatcat
      301 ccgctcccgt caggcctcga cgtacgcccg cagttcgtcg agttcacggt gccatccttc
      361 cgtgttctcc ttgaccgcca gttcctgatc cccgctaagc gcggtgaagc cgctctcgat
      421 gacccgcagg cgcgttccgt cgccgtcctc ggacagggtg aactcgacca gcgtctggtt
      481 gcccggtgcg ggatcggtgt cggcaggacg agcccaccag taggagaacc gatgcggcgg
      541 ctcgacggct gccaccttgc cgtggaaccg tccgtgcggc gcccagccga agacgatcgc
      601 gccacctggc cgcaggtcga cttcggcctc atcgccgaac cactccttga tgtgcttttc
      661 ctcggtcaac gcggcccaca ccttgtcgat ggacgcggag atggtgatgt cgcgctgaat
      721 ggtgtcggaa accatgaacc ctcctcggtt gatatgcaac ccaatagttg cacatcgcac
      781 cgctatgtgc aaccggtgag ttgcacgtcg gaaagtgcgt gcacgcaaga tatgctgcgg
      841 aaatgagcgg actgcgtgaa cgcaagaaga tcgctacccg ggaggccctc agcgctgcgg
      901 cgctgcggct ggcgctggag cgtggtccgg agaacgtccg cgtcgacgat atcgccgagg
      961 ccgcgggcgt gtcgcccagg acgtacaaca actacttctc cagccgtgag caggccatcg
     1021 tcgcggcgat tggtgccgag cgtgcccacg ggatcgcgga tgcgctgctc gcgcgcccgg
     1081 ccgaagagtc cctggccgag gcggtcgtgg cggccatcgc tgagcagtac accagtgagc
     1141 cggcgggtga cgcgctcacg ttgatcacca ccgcgcccgc gttgcgggag gagtacgtca
     1201 agacggtcct gtcgatcgaa tcgcccctcg catccgccat cgcggcccgg accggcgtcg
     1261 acgacgaact ggccacagcg gtgctcgccg cggcgatctc ggcggcggcc agggtcgcgg
     1321 ttgagcgatg gattactcgt acggagtcag gtcttgttgt cgtgcccgcg attccattgg
     1381 ctgatcttct gcggaatgcg ttgttccacc tggctccggc aatggatgcg cttgtttcac
     1441 gggagcgctg aaccccactc aaaaacacgg caagcaacat cggacaactc aagaagcctt
     1501 gcgaagccac acccggcgtg gatactctcg gccgggacgt gcgggaggga cctgttctct
     1561 ggggtgagag gtgggtcgtc caggtggaca acgaagtttt ccggtcattc aacgcggtgc
     1621 cgggcgtgtg cgcggcgcag gttgatgcgc gcggagtggt ggtgaaggcc agccagcagc
     1681 tctaccggcg gctcggctgt cacccggacg accttcgcgg acggtacttc atggacgtcg
     1741 tccggcgtga cgggctgcgc ggcgagacga tcatcgtgat ggtcgaatcc gagcaggagc
     1801 gccggccgga gaccactggc ggcggcacaa aaaagatact gaccaaaatg gactcgcgga
     1861 ttctcgaagg tgtcgcggcg ggcgtgtcga cggccaaact cgcggtgatg gtcgatctca
     1921 gccgtggtgg cgtggaatac cacgtgacga atctgctgcg gaaacttcgc gcccccaatc
     1981 ggacttcgct ggtgtccaag gcttatgcgg aggggattct cgaggcgggg acgtggccgc
     2041 cgaaggtggt acccgacttc gtgaagtagg ttctgcgggc atgccgctgt tctccttcga
     2101 aggcaagagc ccgcaggtcc acccgtccgc ctggatcgca cccacggcca ccctggtcgg
     2161 tgacgtgatc gtcgaagccg gcgcttcggt ctggtacggc gcggtgatcc gcgcggactt
     2221 cggccggatc gtgatccgtg agggcgccaa cgtccaggac aacgcggtca tccacgtcgg
     2281 cccgaacggc tgctcggtcg gccgcggcgc gaccgtcggg cacctctgcc tggtccacga
     2341 ctgcgtgatc ggtgactacg ccatcgtcgg caacggttcg actgtgctgg atggttcgcg
     2401 cgtcggggaa cgggccatga tcgcggccgg gtcgacggtg actccggctt cagaggtccc
     2461 ggccgaggtg atggcgatgg gatcgccggc caaacgccat atcccgctca ccgacagcgc
     2521 gcgcgagtgg atcgacacga atccgtcgct gtaccaggag ctagcccgcc ggcatgcggc
     2581 gggcatcgct gaggtgtgac ggtcagccct tgtcgaggac ttcacgcagc ttggccgcga
     2641 acgcctcggg ctgaccggcg tatccgaact cctcgccgag gaagccgccg tggtggctcg
     2701 ggaacacggt cacctcctgg ccgagcagtt cggcggtggc gaccgcggtg cgtccggtga
     2761 agacgtcctt ggactcctca cccacggcga tcaccacgcg cgtcgaggcg gtggtcagcg
     2821 cctcgacgtc gggccggtac tggacgatgg cgatggcccg gtcggacagc agcgggtcgt
     2881 cacgcttgcc gtcgtcctcg gtcggcatcc cgaactgggc gggatcggct ggcggctggg
     2941 cgaagtactc gtcggtgaac tcgcctttcc acgccgtcat gccgatgaag gtcgccatcc
     3001 cggcgccgaa gcccttggcc tggtacgcct ccaaataccc gttcagcgcg cgttcggctg
     3061 cgggcgcgtc gggcagtacg tggatgagcg gtggctcgtg cgccaccagc gtgaccacgt
     3121 cactcgggta cgccgcgacc cacgcgagcg cggtcaccgc gccaccgctg ctggcgaaca
     3181 cctcaaccgg gcccgcaccg agcgcctcga ccagagcgtg cagatcgcct gcctggactt
     3241 caggtctgct gtcgacccgg ccgtctttgc ggttgctgcg gccaagccca cgcgggtcgt
     3301 acgtgaccac tgtgcggtca gggaagtacg aggccagccg ggtgaacccg gtggcgtcca
     3361 tcggctggcc gatcatgaac aacagcggcc gtccgtccgc tgtcggcagc ggtccgtgca
     3421 ggtcgtacgc gaggtcgacc tcggcggttt ccaggatgtg cgtcgtcacc atgacagtaa
     3481 gacccttcga gtgtcccaaa ctcatcggac cctacgtcag tgatcagtcc agacctgaca
     3541 actccggtga attgctccgg ccggacagcg acaaggacgc attctgcttg gaaacgcgga
     3601 tcgcgaggac gacgagcacc gcgacggcga agatgggata gctgctacct gctatctgct
     3661 gcagcgcgtc ccagccttgc tcgcgattga ccgtgttcgg ccaccaccag tgcgccgaca
     3721 gcgagaacac caccagcccg gcggccgcga gcaccttcga atgccaggcg agtgccagca
     3781 gcagcggcac gcaccagacc cagtggtgcg accacgaaat aggcgagaca agcagcatga
     3841 tcagcgcgtt gatgcccatc gccagcgcga ctttgccgtc cgcgagcaca gtgcgcatcg
     3901 cgaagatgcc cagcacgagc accacggcgc acaacccgat ccagaccacg ctgcgcagcg
     3961 gcggttcccc gccgagccgg agcagcacgg ccagaatgga ctgatttccg gcatatccgg
     4021 caccgacccg gtcactgccg aacatcgcgc ctgtccagaa cttgaccgag ttctcccacg
     4081 agatcagcgc accgatgacg ccgaacgcga cgaaggacaa cacagcggtc accgcggccc
     4141 ggaaatcgcg cctgagcagc aggaacagca ggaaggccag cggggtcagc ttgatcgccg
     4201 cggccagccc gatcagcagg ccccgaggcc agcgcggcga cttgaccagc aggtcgagca
     4261 cgaccagcgc catcaggaag atgttgacct ggccgaagaa gatgtggtcc cggaccggct
     4321 cgatgaacag cgcgaacggc agcagcgccg cggtgagcca ccaggggttc gacgcgccga
     4381 tcgaccgcag taccaggacg atcacgaggg cgaccaacgc gattgtcagc agcgtccaca
     4441 gcgcactggc cacaccgaac ggcaatatgc cgagcggcgc gaggaacgcg gccgcgaacg
     4501 gcgggtacag gaacgggagg ctgatcccga cctgggtctc cggcatccgg ccgtagagat
     4561 cgccgccgtc ccaccagacc ttgagcccga tccggtaggc gtcgatgtcg atccggtaga
     4621 cgtcgaaact caggccgcca ccgggagtgc gggcggtcag catccacaac aaggcgaaca
     4681 gattgagcgc ggtcacgacg acgacgccga gcgcggttgg tcgcccaacg gcccgtagca
     4741 ggctcaacgt gtgtcccccc gaccctgaat gcaagtcacc taacccgtgg cttccagatc
     4801 cgtgctttcc ctctacgagg aatagatgcc gtagcggtgc aaaaggttgg ttcaggtgag
     4861 catgatcata ctcggatcac acacgcccaa gaccgttgtc gagggtatcg gacgggtgag
     4921 atgcgctttc acgcacggcg tggtcagctg ccgcggaccg cgcggacggt cgcggcgacc
     4981 gggctgagca tgagccaggt gggcaggctg cggatgaccc atcgggcacc ggtcaggccg
     5041 atggatccgg ccttgacggc gtcaagcagt tcgatctcac cctcccacat gcggtagagg
     5101 gtcggcaggt cggcgctgag cacggcgtcg atgtcgaagc cggggtcggt gtagcagatg
     5161 gaggcgtcgc ccggctcgag cacgagccag aactgtctgc gccggtcggt gacgtcgatt
     5221 tggatgacgg cgcgtttgac cagctcactg gtgtcgatgc ggccgtgcat ccaccacatc
     5281 agcacctcgg gatccagttc gtaaggctgc gggtcgccga acgcgtaccg tgcgccccac
     5341 tcgccgagac tgaagacgat cggccgaagg tccgtccccg ctttggtgag cgcgtagccg
     5401 tcgtcggtcc gcgtgaccag gccggccttg tgcagctggc ggaggcgctg ggcgagcagc
     5461 gcccgggaga tcccgggcag gccgcgtgcg agctcgttga accgggtgga gccgatcagc
     5521 atgtcgcgca cgatgagcaa cgtccaccgg tcgccgagca actcgacggc gcggacgatc
     5581 gggcagtact gggcgtaggt ccgcatgttc atatgtcgtg accaggcacg atatccgtta
     5641 cgccgggttc agttttagaa ctacctgtgc gccgcggacg ttcttaccgt cgtgagccat
     5701 gacgaccatg acgcttcaaa caggcacata cccaacacca gtccggcccg acgacacccg
     5761 gttcgtcgac ctggcagccc gagtcggcgc gatcgccgcg gagcacgcgg cctcgcatga
     5821 ccgggacgcg accttcgtgg ccgaggcata cgcggcgatg caggagtacg gctacctagc
     5881 cctcgcggtt cccgcagagt taggcggctt aggcgcgaca atccgccaag tctgttacgc
     5941 ccaagcggaa ctggcccgcc acgacggcgc gacagcgttg tcggccgcga tgcacaacta
     6001 tctgacgttg atgcagtgct atcgccgtcg aatgggtgct ggtgacgccg agaccgtgtt
     6061 gcggaaggtc gccgagggca tggtgatcgc gacaagcgga ggctcagact ggctctggcc
     6121 gacgacagtc gcgatcccca cagacgacgg ctaccgcgtg acgggccgga aagccttctg
     6181 cagccaggca ccccgggcga acgtggtgtc gacgagcgcg gtgctgccgg accagtcgga
     6241 ggtcttgcac ttcagcgtgc ccttggacgc gcccggcgtc cggatcgagg aaacctggga
     6301 cacggtgggg atgcgcggca cggcgagcca tgacgtcgtt ctcgaggacg tcttggtgcc
     6361 ttctggcaag atcgtgggcc gtcgggccta cggcgagttc ggcgtgccgc tgctggccgc
     6421 gactgtccac ttcgcacctg tggtgggcgc tacgtacttc ggaattgccg ccggggccag
     6481 ggatctcgct gtctcaaagg tctctgtcga tcgccgggcg gcacaggtgc accggcaggt
     6541 cgggttgatg gacgccaagc ttcggggtgc ttggtgggcg ctgatgggct ctcttgacga
     6601 actgggcacg gagtacaccg tgaacccgga gactttgacg accgtgatgc ttgccaagcg
     6661 ccaagccgtc gttgaggccg tcgaggtcgt caacctggcg atggatttgc tcggtgggcg
     6721 gtctttcttc cgtcgcgcgg ggttggagcg ggctttccgg gacgttcgtg cgggcacctt
     6781 ccacccgctg aaccccgagg tcacgttgtc ctacgcgggc aaggtggcac tcggggacac
     6841 cggggtcacc gaatagattg gccgaactgg aagaggttgc cggggtcgta cgccgccttg
     6901 acctctcgca gccgggggac gttcgggccg tagtaggccg tcagccagtc gggcagcgac
     6961 gggtcgggaa agttggggta ggcgcccgtg ccctcgagcg tcttccagct tgcggtgagc
     7021 caggcgaggg cttcgtggcc gcgcctggcc gcgccgttgg gaccgaccag gacggtgtgc
     7081 ttgaccagga atgacgggtt ccggtgcggg aacgccgtat caacggtcga tcggtaggca
     7141 ccgccccatg gggtgaaagc gacttcgcgc atctcgccgg gaacgcgtgc cgccacgaaa
     7201 tgcgcgagga gcgcgtcgat ggcggaggac ggcagaggct gcgtgaagaa agcggtcttc
     7261 gctgtgctca tacctgggcg ggagtggatg agggggatgc tcgacgggtc gtgggctgcg
     7321 gcggaatacg gggttgcgtg cagcagtgcg gcttcagcag cggaaaggtg tcgaacctcg
     7381 gcaaggttgg gcttcgggag ctgagtcagc agcgctgtcg gatcgcctgc accgatcagc
     7441 agcatctgtg gtgggtcttc ggcgtagtcg gggctgagga gtatcagttc ggcggatgtg
     7501 gtgttcggtg cgaacggtgc ccactcctgc caggcgtgga ccaaggaggc cgacaggtcc
     7561 caggagaagc ggaaatgggt gcggcgcgtc gatgtcaccg cactgaacgt cgcgctggtc
     7621 accacgccga agttgccgcc gcccgcgcca cgcagtgccc agaacaagtc cggttcggac
     7681 tcggcggatg ccgtgaccac cttccctgag gcgaggacga ctttcgcgga caccaggtgg
     7741 tcgcacgtca gcccgtgcgt ccggccgtgg ctgccgaaac cgccgccgag cgccgcgccg
     7801 atcaaaccga ccgacgggca tgagcccgcg gggaccagca attccaaagg ggagagcaac
     7861 tccgccaact gtcctgttcg gagtccggcg ccgaccgtga cttcccggcc cgacacagtg
     7921 acggccgagg cgggagagag gtcgatgaca aggccggtgc tgctggagta gcccgcgttg
     7981 ctgtggccgc cgccgcggat cgcgaacggc cagtcgcgat ccgcggccaa gtcgagtgct
     8041 tcgagcacgt cgtcgggtgt ggcgcagcgg gcgacggctt gggggaggac ttcgtcccgc
     8101 gttccgatga actggttgcg ggacaacgag tagcgcgggt cgtccggcag tacgaggtca
     8161 agcatcggcg tacatcttcg cttgcaggtc gtgcagttcg gcgtagcgcc cgcccagtgc
     8221 catcagttcc gtgtgggtgc cttgttcgac gagttctcct tcgtgcagaa ggtagatccg
     8281 gtccgcgtgg cgcacgctgg ccaggcggtg tgtgatcagc acgacagtgc gctcctcagc
     8341 caacgcgcgc aacgactcgt agaccgcgaa ttccgccttg gcgtcgagtg gcgcggtcgg
     8401 ttcgtcccag atgagcagtg gggcgtcacg gaacaggcca cgggctaccg cgagccgttg
     8461 ccattggccg ccagaaagct cctgaccgcc gcggaactgc ttggacagca aggtgctcca
     8521 gcccgagggg aggcggtcga cgacttcgtc ggcaccggac tgcgcggcgg cggccacgag
     8581 agcgaccgga tcgtctcggt cgtggcgtcc ggcttggaca ttcgcccgcg cggtgtgcgg
     8641 ccagcggatg gggtcctgca gaaccatcat cacccgattg gcgatgcttg cccggtccag
     8701 cgagtgcacg tccgtcccgt cccagcacac caggcctgag gacggcgtgt acagaccggc
     8761 gatcagcttc gccaaggtgg ttttgccgga gccgttctca cccacgagcg cgatggtctg
     8821 accgcgctcg atggtcatgg acacgtcccg tagagcggcc tgcgggctgg ttggatacgt
     8881 gaagctgacg ttggacagtt gaacacggct cgggtccgcg accactgcgg gcaatgccac
     8941 cggcgggcgt tgcgcggagt ccaggaacgc caagtagtcg gccacgtaca tgccctgctc
     9001 gaccagctgg ttcgaggcga ggaccaagcg gttcaaggca gtcgtggacg ccctgatggc
     9061 gatcaccgcc gttccggcga cggccaacgg aacccacgac gcgtgcacca aaagcccgag
     9121 aacgacatac gtgacggcca acccgacgcc ggcgagcgca cggccgacac cacggacgcg
     9181 tgcctgggcg acaccgcgcc gaatgtcctc gtcccgcaac gggtccgcga caacgcggta
     9241 ctcgtgcatg acgaacggct cggcctggca tgcccggatc tccgccgcgg gctcgcgttc
     9301 ggtggccagt tcggcgacca tctgcactcg tctgtccaaa gtgaccgcac gggccatgct
     9361 cgcgtaagcc agcattgccg atcgctggac tgcccacgcg tcaggtatca ctgccaacag
     9421 tagtacaggt agtaatacag ggtgcagtac tgcgaggctg ctgaccgcgg cggcaatgcc
     9481 cagcaccgag ccgatgagct cgaccaggtt gtcggttgac cgctcgatgt agaacagccc
     9541 acgatcccga gcccggtgca tccggtcgta gaactgggca tcgtcgaacg cggccaattc
     9601 cacgctcaaa ctcgcctgat acagccgttc ctcggccaat cgccggactg cgggagtgat
     9661 gcgggcgtgc gcgatcgcca caccgatgtc catcgcgccg cgcaaggcat acgccccgcc
     9721 gacgaacagc aaggacggca gcgcggcgac gacacgatca gcggtcggtc ccgaggagaa
     9781 cagttcggtc agcacctcgg ccgtcgcgaa caggccgaac gccgccgcca accccgaggt
     9841 cacctgcatg atcgcgatga gcaatgcgga cctgggcgcc gcgtcccaga tcatccgcag
     9901 caccggccac gtcacccgtg gcaggctgcg gatgactcgg cgcgggccct ccgccttctc
     9961 gtcgatctgc caatgcgggg tgttcagctc ccgcggatcg tcactcaccg ggcaccaaca
    10021 ctgacggcag cgtgcattcg gggtgcatcc gcagcagctg gtacgccaca ccgcccgaac
    10081 cggacatcaa gctcggcgag tacacctcac gagccagacc ggtcgtcgtg ccgtgcgtct
    10141 ccaggctggt gatgatctgc gcggttctgg aggcgcccag caactcccag gaccccatgt
    10201 cgccgtgaca caacgtatgt gtccagccga agccgccttc ctcggtggcg gcaacagcac
    10261 gccgcaggac atcgtggtta cggtcgggcg cgaacccacg gcccaacaga tccgcggccg
    10321 cgagcccgac accaagcgca ccatggcacc acgcggccac ggttgacgtc ggctcacgcg
    10381 ggtccaacca cccgccgcgc tcggtggagt accacgtctc ctcgaacgcg gcagcctcgt
    10441 cggccaatgt cgcgaaccgc gcctcaccgg tcgcgagcga gagcctggcc agcgcccagc
    10501 cgatacccgt cgaaccgtgg gcgaagccgc cgatcccgtc cgggaagttc gccaccgacc
    10561 agcagacctg gccgggagcg ggccgtaaca ccgtcgcggc aaggtgatcg ccgacctgga
    10621 cagccaggtc cgtccactgg tcgtccccgg tccgctgggc cagcatcagc aacggcacga
    10681 tcgacccggc cgaaccgacg acgaggtcag gcccttcact ggcctcgatc gctgccggca
    10741 gctgcgcggc gaggaacagg gcgtcctcga catggcccag ggtgagccag caccagatct
    10801 gcgagccgag tccaatgtag ccaccgggcg ggtcgggacg ccgtttggtg tgcgtcgcct
    10861 gctcggccca ccagtgctgg gtccgccgcg cggtctggat aacgccgtcc agcaggccat
    10921 cggcctcggg aacaagatcc gctcgcccgg ccgcgacctc ctgcgcgtag ccgtccagca
    10981 ggacagccac gccgagcgtt ccgctgtaca ggtcgggcgt gagcggcgtg gtctgccagc
    11041 cggagcggtc caggatgggc gcgaaccacg ttacggttcc gtcgctgccc cggacggctt
    11101 ccgaagccag agtacggatc tcggcagccg cgagcgcccg gcgccgagca tccacatcgg
    11161 actcttcgac ggacgtgtcc atctgccgca gatcaggctc ggcaccctgg ttcagatagg
    11221 cactgaccaa ggcggcgtgc gtgacccggc gctccagcgc gaaatcggct tcccgccagc
    11281 gctgcaggca gagctggatc tggtcctgcc gcggcccgca gaccgttcct gccggggtgt
    11341 gcagccaccc ttcggccggt gtcgtggtga acaccgggat gtcaccgatc agcaactcgg
    11401 cgacctcggc cgcgtgcacg gcctgttcgg cgggcccacg ggtgttcatc gaatgccgtg
    11461 cgatcagtgc caaggctttc tgctcggcag cgggctggtt gtgcagaccg accgggtgcc
    11521 acagcattcg ggcgagttcc gtgtacgcct ctgagtcgcg caccaccaca cgcacaacac
    11581 agtcagaaaa ccgctgaagg agcggttcaa gctcgccgga gcggtccagc gcgttgatcc
    11641 gggacgccat cgcgtcgaac ccggcgacca cctcgcccca gtaacgcccg agctgagggt
    11701 tgcggctcgg caggttctgc gtcggcggga gttgttgggg cgtaatggcg atcttggctg
    11761 tgtcggttcc ggcgccgacc aggtcgggca ggccgatgtc cggttgctgg ccgggcagca
    11821 tgcccatcgc ggaaccgtcc acaccgcgcc agccgaggcc cgcgccgcgg cccgggagca
    11881 ggccggttcg catcacggtc ccgttcaaca gttcggcggc acggtcggtc gcctcgcccg
    11941 cgccggtcgg cggatgcggc ggccggggcg tgaagatgct ctcgcagtcc acgacgaccg
    12001 ggatcggccc gcaggcgatg atgttctcgg catgcaagtc ggttcctgac accaggcgca
    12061 tcaccgcgag ccagtggccg aggttccggt agaaggtgct gagctcggaa tcgctgtcac
    12121 agtaacggtg tgccacgtgc tcggcccagc cgtagccgtc catcacgatc gccctgggca
    12181 ccctgatgcc ttgcgggtca aggacttcca gcaggccggc gagctgggcg tcgacctgca
    12241 tcgggcgcgg cttgtaaacc actgtcccac cggcacagtg catcaacgaa acggtgtgac
    12301 cgccacggtg gctgtcaccc gcaccgatct cgatcttcag cagttcgccg acatcgttac
    12361 cgagcaacga acccagcttt ggacggtcgt cagcgaaccg tgttgccatg gcgagcacgg
    12421 ccgcgcatcg gttgtccacc acggcttgca gccgttcgag cagatgcggg tagtgctcgg
    12481 tcaagccgtg ccaaaacgct ggttcggtgg cggttcgcag gaactcacgc caccgtccgg
    12541 ccgggtcggg tgcggtgagt ttgccggtga cccgtgcggc gttgagctcc agcacgatga
    12601 cccggttcac cttgcggcgc accgaatcga gcaggacctc gcgggtcgcg tcgacgaagg
    12661 cgccgacctc ggcagcgacg aggccggcga gcccggccag gcggccgtcc agccggtgca
    12721 gtgccggtcc gatcagccat tccacagtgc ggtcgagctc gccgacctcg tcaggtgcca
    12781 tggaacgggc tcagcagcag aagaccggcc gggacgcggt gcacgacgag caccggctgc
    12841 caggcgggtt gcaggccacg atgtcaccct cggcgaactc gccgctggcg aagatcgggc
    12901 cggccgggct gtccaggtcc aggccttctc gccaacgagc cacgagctcc tcggcatccg
    12961 cgagcatggc agctgtcatg gttttcccct ttccttgctg ggttgggaaa aacgacacta
    13021 agaacgccgc gcatacagcc gcgcacacac gtgtgcatac agccggtcaa ccacgccggg
    13081 ccaattcgtt cagctcggtg gtggcctggg ccggccgcac acccagctcc cggtccagca
    13141 gcgaccacag ccgctggtac tcctccagca cctcgctgcg ccgcccggtc gaccacagtg
    13201 cgagaagcag ctggtgccac agccgttccc gcaacgggtg ctcgatcacc aggcccttca
    13261 ggatgggcac gagatcctgc tcgtgcccca acgacatccg gacctccacc agctcctcgg
    13321 tcgcggacat ccgcaagtcc tcgagcatcg cggcctcggc ttccagcgcc gccggaatgg
    13381 gcacgccctc gagcacgtcc ccgcgccaca agccgacggc ctgggtgagc aacctggccg
    13441 cgtccagccc ggtgtgctta cgggcctggg cgacaagttc ccggaacagc aacgcatcga
    13501 cgccatgcgg tgccgtgacg agcatgtagc cgtcgtcgag cgtttcgata ctcggcttgt
    13561 ccccgcccgc cagcagacgc cgcaactccg cgatatgaga ccggacgttc gccgcggcgg
    13621 acgcgggcgg tttggttggc cacaacccat tgatgagcca ctcgagtgag agcggccgat
    13681 tcggccgcaa cgcgaacagc ccgagcaaaa cccgggccat ccgccggagt ggacgtaatc
    13741 cattgccgcc gatgtgcacc atcggccgcc ccagcaccat gatctccatc aaccgccccc
    13801 gtgcaagacg aacacgcatc agctatcgcg tttcgcccgc gctgcgccac cggcggacgg
    13861 gggaaatctg ttgcagtaac agtgaaatca gtgcgcggag gttcggtcgt ccagctctgc
    13921 gtagcgacat ccaggctgac cgtagttgtg cacggcgcgt ccaccggaga acgcacggca
    13981 cgtgcaggcg cctggatact cgaaatcccc gccggaccgt cgccgtcgtc gtccagcagg
    14041 gtggtggatg aatcggcgag ccatggcggg acgctcctct cggcgaatgg gcgttgatcg
    14101 gcggtgctct tcggctgccc gtaacccggc ctgcgcaaac gtgatcgccc aggtagtcgc
    14161 ccgattagcc caatcacggt gtttcaggtg gtagaacagg gtccatgcag ccgctgcaag
    14221 ccctcggtat ctcggctgac gcggaacggg tgtacctcga cctcgtcgag cacgggacga
    14281 ccggcgtcga gcccgagcac aaggccgtcg ccgagctcga ggccgccggc ctggtcgagc
    14341 gcagcggcgg caccctcgtg gcctgcccgc cgcagctggc aatggaggcg ctcgccgagc
    14401 gctacacggc actcgccagg cagagcgcgg ccatgttggc cagggtctgg aacaagacga
    14461 acgacacata cctggaagtc ttaccgtcct attcggccgg tcgcgcggtc ctcgaccggg
    14521 tgcagaccga cgcacggacc cgggtgcggg cgctgagcgt cggcaacctg ggcccggacg
    14581 ggcacaagat cgtcgagggc ctgttcgacg cgttggcgcg tggcgtggcg tatcaggtca
    14641 tctacggcac gcacgtgctg cgtgatcccg aggcactgcg gatggtccag cggtgcgtgg
    14701 acgcggggga gcaggcccgg gtgttcccgc acgtgtcgat gaacttgacc attgtggacg
    14761 atcgatgggc gttgctcacc gcccggtccg acgaggacat cgcggcggtg gtcgtgcacc
    14821 ggtcaccgtt gctgactggt tttgtcggga tattcgacgc ctactggcgc atggcggtgc
    14881 cgatcaccgc gggcaccgag acggcgcccg ccggtgacac accgagccgg gatacccagc
    14941 ggctgctcac gtacctcagc gcggggctga ctgacgaggc gatcgctcgc gagttcggcg
    15001 tgagtgaacg gacggttgcc cgcaggatca gccgcctgca ggagatcctg ggggcgcaga
    15061 ctcgcttcca gttgggggtg caggcatcac ggcacggctg gctgtgagcg cccgttcagc
    15121 gttctcgcgc tgcttgggga tccgcaggat aatggggaag tacgcaagac acagaactgt
    15181 ggcgatagcg cagaccctcg cgtactccgg atcgacgtcg atgatcagga ggctgaggcc
    15241 tagtgtgatt gctatgcttg cgaaccacgc gagaaacacg gtcactgccg agggccggcg
    15301 aagtatccac tgggcatagc gtgccactat ccgcacgtcg gccgcgttgt cgaccggtcc
    15361 accgtcccgc acgattcgcc acgccttgat cttttcctca aggagggtca ttggtggaaa
    15421 ggccgcaagc atctgtttgc gcacgctgag actcccgagc gcggcgccga gacccgaccc
    15481 ggccgagacg atcaccgggc cccaggcgaa tcccggccgg gcgatcaacc agacgatcca
    15541 catcaccatg cccatggtga ggccgttcac cagcgcccac catccccgcg ggccgaaggc
    15601 tcgcctcatc caccattctt ccactggtcc gcctcggtta tcgcttcggc acttcgagca
    15661 cacgttccgc gttccagagc catttcgcgc gacgcatggt catggggatc atcgccgcga
    15721 acacgaccag gtacagcgcg ggcactcgga cgtagaaggg atcgtccttg ggagcaacga
    15781 tgatgacaac cgccgccacc gatatggcca cggcgagccc ggttgccaag gccgaggtac
    15841 tgggcccgct aagcagccac cgggcgtgat ggttgacagc cgatacatca gctttgttct
    15901 cgactggacc gccgtagcgc acgagccgcc agattctcat cgtgtcgtcg aggtgcagac
    15961 cgggtgggaa tggtgggggt gcctgactgc gtccgaaagc gctggcggct gcgaagcaca
    16021 gaccgctgaa agccgcgaag aacacgtggc gcagctcgaa gctgaaatac ccgaccaccc
    16081 acgaaaccca gacgactcca gccccgatcg aagccgtcag cagcgtgaac aggccaggag
    16141 agccgaaccg cagcctggcc caccgctcag ccatgtctta cgccgagcac gtcaagtgcg
    16201 tcttccatcg gcgccccctc cccctttgat cacgtacatc gcgttacacg cgtaagggtg
    16261 ttaccgaggt tgcctggaac cggccagaat agttcacaac ttgctgctgc ggtgttaacg
    16321 attccgttcg cgccccagca acggcgcgct cagcagagtt gcggccgtga aatccttaaa
    16381 actcttcgcg atcatcaccg ctgtggcggc ggtcgcgagt accgcgacgg tcagtgccag
    16441 ccccgaggct ggcaagccat cgacgtgccg gacgccgccg caggaaccgc cgccgttgac
    16501 gccgacgacg gtcaccacca tcggtcaggc gtattactgc atcttcgaca actacttcag
    16561 cggtcccgtc ttggacagcc gtgacctttt acaaccggcc ttcgccgcgt tcaccaggga
    16621 gctgcaacgc cgggggcttg accaggcgaa cgcgagtgct ccggtgctga ccggcaagcg
    16681 ggacgccgac tggcgggcgt tcagcaaggc ttaccaggac attgtcgcca agctgcctgc
    16741 ggacgtgcac caggctgtcg ccgaggtgac catcaccgcg atggtcgaca gcctcaacga
    16801 caaccacgcc cggtggatgc gcccgacgga gtcggactcc gtgccggtcg gcttcctgcc
    16861 ttcgcacgcg cgaggcccgg gccggaccga tcccacgacg agtggcccgg ccttcgtggt
    16921 ggacctgttg ccgggcagcg cggccgcgaa cgcgggcatc aaactggggg acgagatcct
    16981 cacggtcaac gacgtaccgc tgttcatcaa cggcgtcgcg gttccgggcg tggtcgagtg
    17041 gctgatggag gccaaggaag gccagcaggt caagctgacc atgcgcaggc cgtcgaccgg
    17101 cgagaccaag acgtacacgc tgacggtgac caagccgtca ggcccgccgc cgcagcgtga
    17161 ggtggtcgag tcgaagctgt tgcccggtga cgtcgcgtat gtgtcgatgc gcggcttcgc
    17221 gcgcgatgcc gcggacaagg tgctcaaggc catcgcggat ctggggaagg accgcacact
    17281 gcgcggggtt gtgctcgatc tgcgtggcaa cggcggtggg tcgcctgacg aggttaagaa
    17341 gctggtcagc tcgtgggtgc acggcaagac gtacagctac tggtgcgacg tgaaggacaa
    17401 gtgcacgccg aaccgcaccg acgactcggt gccgctggtg aacttgccgt tgatcacgtt
    17461 gaccgaccgc cggtgtgcat cggcgtgtga cgccttctcg agtgctgcga aggtcttgaa
    17521 gttcggcacg ctggtcggcc agcgcaccgc cggtgccgtc tccggccctg gggacgggtg
    17581 ggtactggac gacggcagca tgatcggctt gccgaagatc cacgagatcg ggccggaccg
    17641 ggccaaggtc gacacggtcg gcgtgccgcc cgaccacttc gcgccgatca ccgcggccga
    17701 cctctccgct ggccgcgacc ctggcgtggc gaaggcactc gctctgctga agtgacgttc
    17761 acgtggggga aacgtccgat ccgctaggca ctgggcatgc gagtgctggt ggctgaggac
    17821 gaacgggacc tggcagatct ggtcgccacg gggttgcgca ggcacgccat ggcggtcgac
    17881 gtggcctacg acggtactgc ggcgtcggag cggctagccg tcaacgacta cgacgtactg
    17941 gtacttgatc gggacctacc cgaggtacac ggcgacaaga tctgccagga cctggtccga
    18001 tcgggggcac ggaccaggat cctgatgctc accgcggcgg cgtcggtgcc cgagcgggtc
    18061 gccggtctcg gcctcggcgc cgacgactat cttccgaaac ccttcgacta cagcgaactg
    18121 gtggcacggg tgcaggcatt gggcagacgc agccaggcac ccgtgccacc gacgttgcgg
    18181 cggcacggga tcgagatgga cacgcaacgc atgcaggtga tgcgggacgg ccggttcctt
    18241 cgcctgtcac tgaaggagtt cgcggtgttg gaggtgctga tgcgagccaa tggcgcggtc
    18301 gtcagctccg aacggctgct ggaatcggcg tgggacgagc acacggatcc cttcaccacc
    18361 gtggtccggg tgatcatcag caggctgcgc gcgaaactcg gggacccgcc gtgcatccag
    18421 accgtgccgg gcgcggggta cgtgctgtga gacgccggac catgcggggc aggctgaccg
    18481 ccctgtacac ggggatcttc ctggtcacgt ccacgatcct ggtgatcgtg gtgaactcgg
    18541 tcttcagcga ccggctgcac gcccaggtcg cccagatcac cccgggcggc cgccccgtgg
    18601 ccaggcccgt cctcccgccg atacctccag gaccgttcgc ggacgtggag aacctgccgg
    18661 acgaagtgct gcgggaccaa tggacagcaa ccgtgatcac catcgtggtg ctgaccctgc
    18721 tgtcgatcat cgcaggctgg tggatggccg gccggatgct tcggccgctg cgccggatca
    18781 ccgcgacggc gcaacggctt tccttgtcca acttggacga acgaatcgcc ttgacaggcc
    18841 ggaacgacga actgaaagag ctcgccgaca cgttcgacgc gatgctcgaa cgccttgaac
    18901 gttcggtgga cagccagcgc aggttcatcg ccaacgccgc gcacgaactg cgcacgccgt
    18961 tggccacgca gcgcgccgcg atccagatcg gactggagga cgccgaggac ctgcctgagg
    19021 tcagggcgaa actgctgacc cacaatcaga ggaccgaaca gctgatcgac tcgttgctcg
    19081 tgctcgccga agccgatcac ggtcttgatg cgccacaacc ggtcgacctc gcagcgctcg
    19141 tccggcagac cgcggccgaa tcgacctccg aagcgatcgc catgactgtg tcgaccgaac
    19201 cgcttgtcat tcggggcgat ccggtcctcc tgcatcgatt gctcgtcaac ctggtcagca
    19261 acgccgtccg ctacaaccac cccggtggat cagtacacat cggacttacc gcattgggac
    19321 tgctgaccgt ccggaacacc ggaccgcacg tacccgccga tcggatcccc gagctgttcc
    19381 agccgtttcg ccggttgcac acgcggacac ggcacgacgg cgccggcctc gggttgtcga
    19441 tcgcggcatc gatcgcgcgg gcgcaccacg cgaggatcac ggcccgtccc aacgacgacg
    19501 gtggtctctc gctcaccgtc gaattcggta tcccaacgac agtaccggta tcgcgatagg
    19561 ccggaggtgg cgagaacctg ccagtcggcg tgcccgtaac tcatccggcg ggcttggtgt
    19621 tcaaccgtta gcttcggaag gtatgacggg gctttggggc atctccttcg acgccacgcc
    19681 catctccggt gtcgtggtgg agttcgtgaa gacggcaaag cacttcgctg atcgtggtgt
    19741 gccggtggtg ctggatctcg gttacgacat caaggccgac aaggacgcgt tcttccggcc
    19801 ctaccaagac gaagcccagc tgctgccgga gtgggtgcgg ctcggccgga tcgcaggcgt
    19861 cgagcagatt cccgggtacg acagggactt cgtcgccgag gtgctgcgcg aagtggtcgg
    19921 acgcggcgaa ggaacccacc tgctgccccg gatcgactcg atcgcggagc ggctcagcga
    19981 cttgatcgtg gcggcatggg aagccaacga catcgagtac gtgctggtgg agaacggcac
    20041 gctgcccgag aacatcacgt acaccaaggc tttgcacctc gcgatcgaga agtacggccg
    20101 caaccgcggg cggtacgtcc tttggcgtga ccacgacctg atgtggcaga gcgaaccgag
    20161 ttccggcaag tacggcgtct acccgtatcc ggcgacgccg aaaccgccga attcgccgca
    20221 tatccactac ctggcattgc acgaccaagc ccgccgcaag acgcttgaat gggcgccgca
    20281 cttgcgggcg atcgacgtcc tgccgaacac gttcacgcac cgcaaggcga ccatccacac
    20341 cggtaacgcc gatttccgaa gtgattacgg cattccggcg cgagcacccc tgatcgcgcg
    20401 gtgcacgaga atcatcaggc agaagcggat cgatcgggac ctgcacctgc tggccgggat
    20461 cccggacgcg gtcctgttcg tagcggggga taccaccgaa tccccggacg agtaccgcag
    20521 gcttgtggcg cttgcccggc agttaggtgt gacggaccgc gtcgtcttcg gtgggtggct
    20581 ggcgccgcac gaggacgaca tcggccggtc gacgggatgc aagtattcgg tgcgtgactt
    20641 gctcgcccac gcggacctcg tgtccttcct gacctcattc gactacgaga gctacggaaa
    20701 tccggtgggg gaggccatcg cgtccggagt tccgtacgtg acgacccggt acgaactgta
    20761 cgacacggtc tacggcagca aaggctttcg ggcgcccctg ctcaccgatg atctgccgga
    20821 cgaggacttc atcggacaag tccgggactt gctcaccgac gaggaggaac gagcggagat
    20881 ggcggagcac aacttccggc tgggcgagcg cgatttcggc acggcacgtg acctgttgga
    20941 caggctggtg ctggtcccga tggacgaaca agtccggctc agcgtgatat tgccggtgta
    21001 caacgaggcc gccaacctgc cagcggtcct ggactcgttg taccaccagc gcgggctgga
    21061 ccggtcgacg tacgaggtcg tcctggtgga caacaactcc acggacaaca cagcggagat
    21121 cgccaaaacc ttcgcggccg agcacccgga tctcgccgtg cacgtcattc ccgagcccga
    21181 gcaaggtgtg tcctgtgcac gccggacggg aatgcagttc gcgagcgtgc gcagtcgtgg
    21241 ccgggtcaac gcggaggagc ggttctacct cgtatccgcg gacgccgact gccgcgtcga
    21301 cgaggactgg ctgtatgagt tgttcgtggc catggaatcc ggcaaagccg cgatcggcgt
    21361 ctgcgactat tactactccg ctgagcattt cgccgggcgc ccacggctct gggacgcgat
    21421 caccaagacc ttgcgctgcc gcgcggtgac gttcgcgctg ttcggcgggt tccccgacgg
    21481 caagggcttc gcggtcgacc gtgacgtgca cgaccgagtc ggcgggatcg agatcttcta
    21541 ccagctgcag gacggccggt tcgtcaacca cctgtccgac gactgggact tcggcatcaa
    21601 agtccgtggc agcggtgagg acatcggtta cgtgccccgg tcgcgcgtgg agatcaaccc
    21661 gcgacgtgtc gatcacgcga tcgacgaggt gatcgccggc cgggcctacg gctctgacgg
    21721 gatcatcgtc atgcgggaca tccgcccgca ggccgaaggt actggtgccg acctcaccga
    21781 agagcaagcc cgacaagcgt gggacttctc cgtcaaggac ttcacaccga agaacacgat
    21841 cctgcctgtc ctgctgacac cgtcgctgct ggacgacgac gccgtgatcg agttcttcgg
    21901 gccgtccttg gcagagcggt tgggcaggcg gatcgcggag atcaaggacg agatgcggat
    21961 gacggacttc accccgatcc actcgtacaa aacaccgtcc taccggctgt acttcgagtt
    22021 cgccgacgag atcttcgccc gcctgcgagc gaccgtcggc gacgacatcg gctacccgcc
    22081 cccgctaccg ccgtgtttgc aggacgtttc gccggaccgg ttcaccgagt tcgtgaagta
    22141 ctactgcgaa gacagggaat ccggcgaggc acacaactac ttcggcaacg gaggtgtgtt
    22201 ctgatggact acgcaacggc tttggcgtca ctgcgcgtgc tggacccgtc gcacccacga
    22261 ccacacgtgg cggaagccct tgccgcgccg gagaaccaac acttgctgga atacgttgtg
    22321 gaggatccgt tcggggcaca cgtgttcccc ggcaacgaac cggactacga acccgcggac
    22381 ttccttgccg acctggacac ccagctcgcc gacacggcac cgatccacct gtggtcgtac
    22441 atcccgacct gtgcgtaccg ctgccggttc tgccagtacc cggtcgttct tgccaagggc
    22501 gacaacgccg acgccaaggc aagccaatgg gtggactgga acatcaagga agccaagtcc
    22561 tggctgaggg aagtgcccgc gctgcgaacg gccccgatcg gcgagttcaa cgtcttcggt
    22621 ggcacaccgt cgttgttgcc gccggacgcc atccgcaaac tgctggactt ctaccgttcg
    22681 aacttcacgt tcggcccgga caccgcgatc cggttcgaag gcgacccgag cacgttcacc
    22741 ccggcgaaac tggaactgct ggcgtcgctg ggcgtcacca a
//
