LOCUS       NZ_FUWZ01000021         5601 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000021
VERSION     NZ_FUWZ01000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 5601
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..4357
                     /locus_tag="B5D63_RS34435"
                     /old_locus_tag="SAMN04488128_1211"
     source          1..5601
                     /db_xref="taxon:634771"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070509_121"
                     /organism="Chitinophaga eiseniae"
                     /strain="DSM 22224"
                     /type_material="type strain of Chitinophaga eiseniae"
     region          1..5601
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..5601
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..5601
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<2:4357](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <3..4357
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             <3..4357
                     /NRPS_PKS="Domain: PKS_KR (69-261). E-value: 1e-42. Score:
                     138.1. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34435_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (339-402). E-value: 4.3e-16. Score:
                     50.9. Matches aSDomain: nrpspksdomains_B5D63_RS34435_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (428-713). E-value:
                     1.6e-104. Score: 341.0. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34435_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (878-1250). E-value:
                     2.1e-110. Score: 361.1. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34435_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1356-1425). E-value: 1.2e-20.
                     Score: 65.4. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34435_PCP.2"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="B5D63_RS34435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1211"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_143313384.1"
                     /sec_met_domain="adh_short (E-value: 4.5e-35, bitscore:
                     108.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.5e-85, bitscore:
                     272.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-86, bitscore:
                     277.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6e-19, bitscore:
                     55.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLLKVLSQEYPSLQTSHIDVSLSEEGWQPLLAAEINTPGNGRVIC
                     LRHGRRWGRHYERLETSVSAMPGGGIYLVTGGLGGLGYTLSKRLLADNAAGLILTGRVA
                     LPPRAAWDAGDLEAGVKARIEKIRELESRGCRVLYSHCDLTDVAAVRELVASSEAVLGG
                     RISGVVHAAGIADGESHGGIDTLTQQDYEKQFGPKVQGLEVLQTVLGDRALEFFAATSS
                     LSTVLGGIGFGAYAPANAYMDAYITSGVGTGSLKHWISICFDGLEYGDKTGGGITGGEL
                     AEVWRRIMSVRHLPQVVVSVSDLQLRLQQWVNREVAVAEGGEAMAAGDDKASEDDITAS
                     LIGLWEQFFGKQGITAEDDFFEIGGNSLKALTMMGRIHKLFNVEVPVKTFFDNSTITLL
                     AAQMNTLMSAGNAGRKEYTAIPSAPLKPYYALSSAQKRLYFLYEMDKDSIAYNLPQVVM
                     LEGALDVAKISLAFNQLLARHENLRTFFEVEDGVPVQKIAAPVTCQIPVVKATAEEVPA
                     VIHNFIRPFDLRAAPLIRMALVAIGSRQHILMVDVHHIIMDGVSENILINDFMALYQEE
                     TLPPLQLQYKDFAEWQQEVASQPWMSVQRDFWMREFEEVPTPLELPYDYARPAAKDQEG
                     HIISFDIDTILTGHLKQLAEAEKTTLFMVLLAAYNILLARVSGQDDVVVGTPVAGRHNS
                     DVEQVMGMFVNTLPLRNQVSGGSSFRELLAAVKAKTLSCFDNQDYQYEALISDLALLRD
                     AGRNPLFDAMFVFQNYEQSTLELPGLTLKPYSTGHAVAKFDMTLSAFEHDGKLLLSMEY
                     ATSLFKEATIQRFVTCFVNILTAITAHPQALIKDLVIIPAEEAHRLLYEWNNTATDYPS
                     DKSLVELFEQQAQQTPDHIAVEFNEERVTYRQLNHRSGQLARHLVHHGVAPGDIVGLMM
                     ERSTDLIVGMLGIMKAGGAYLPLDATYPEEHIRNMLEECRVKTVLTEIPHHEEAPLHAL
                     PEVTAAHTAYIIYTSGSTGKPKGVMVPHRPVVNLAWSQRRTFQITEAEKILQFSTICFD
                     ASVEQIWLALLSGATLVMVSREVILDNALFNQYLRDHAVTHLHATPSFLESVAWEDVSA
                     LKRIIAGGEACPVTLAEKCGGVAAFYNEYGPTETTVTSIEYAVTGPMPDKTYVPIGRPV
                     HNTRVYILGEQLELLPAGARGKLYIGGDGLASGYVNDPELTARKFLWHPLLPEERIYDT
                     GDYARWLPDGQLEFLGRADEQIKIRGYRVELGEIAARLRQHEEVQDSIVIADRQGQHTV
                     LTAYYIPVHGAGILSLDAYMREQLPAYMIPAHFIKMEQFPVNRNGKIDRKALPLVESAA
                     GAEFISPLGDTAEMLANIWSEVLSLNREKIGANSTFFELGGNSLLLIKLQVRMKERLGI
                     NVAVAELFTYSSVAALAAFLDNGNVAVEQFEKTVREEVEGLKNMIDIFK"
     aSDomain        212..787
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34435_PKS_KR.1"
                     /evalue="1.00E-42"
                     /label="B5D63_RS34435_PKS_KR.1"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="261"
                     /protein_start="69"
                     /score="138.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GIYLVTGGLGGLGYTLSKRLLADNAAGLILTGRVALPPRAAWDAG
                     DLEAGVKARIEKIRELESRGCRVLYSHCDLTDVAAVRELVASSEAVLGGRISGVVHAAG
                     IADGESHGGIDTLTQQDYEKQFGPKVQGLEVLQTVLGDRALEFFAATSSLSTVLGGIGF
                     GAYAPANAYMDAYITSGVGTGSLKHWISI"
     aSModule        212..1210
                     /domains="nrpspksdomains_B5D63_RS34435_PKS_KR.1"
                     /domains="nrpspksdomains_B5D63_RS34435_PCP.1"
                     /incomplete
                     /locus_tags="B5D63_RS34435"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       218..310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0001"
                     /evalue="3.10E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="102"
                     /protein_start="71"
                     /score="23.1"
                     /tool="antismash"
                     /translation="YLVTGGLGGLGYTLSKRLLADNAAGLILTGR"
     CDS_motif       644..742
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0002"
                     /evalue="4.20E-11"
                     /label="PKSI-KR_m4"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="246"
                     /protein_start="213"
                     /score="35.4"
                     /tool="antismash"
                     /translation="LEFFAATSSLSTVLGGIGFGAYAPANAYMDAYI"
     aSDomain        1022..1210
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34435_PCP.1"
                     /evalue="4.30E-16"
                     /label="B5D63_RS34435_PCP.1"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="402"
                     /protein_start="339"
                     /score="50.9"
                     /tool="antismash"
                     /translation="SLIGLWEQFFGKQGITAEDDFFEIGGNSLKALTMMGRIHKLFNVE
                     VPVKTFFDNSTITLLAAQ"
     aSDomain        1289..2143
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34435_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.60E-104"
                     /label="B5D63_RS34435_Condensation_LCL.1"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="713"
                     /protein_start="428"
                     /score="341.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="YALSSAQKRLYFLYEMDKDSIAYNLPQVVMLEGALDVAKISLAFN
                     QLLARHENLRTFFEVEDGVPVQKIAAPVTCQIPVVKATAEEVPAVIHNFIRPFDLRAAP
                     LIRMALVAIGSRQHILMVDVHHIIMDGVSENILINDFMALYQEETLPPLQLQYKDFAEW
                     QQEVASQPWMSVQRDFWMREFEEVPTPLELPYDYARPAAKDQEGHIISFDIDTILTGHL
                     KQLAEAEKTTLFMVLLAAYNILLARVSGQDDVVVGTPVAGRHNSDVEQVMGMFVNTLPL
                     RNQV"
     aSModule        1289..4279
                     /complete
                     /domains="nrpspksdomains_B5D63_RS34435_Condensation_LCL.1"
                     /domains="nrpspksdomains_B5D63_RS34435_AMP-binding.1"
                     /domains="nrpspksdomains_B5D63_RS34435_PCP.2"
                     /locus_tags="B5D63_RS34435"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1352..1462
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0003"
                     /evalue="4.40E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="486"
                     /protein_start="449"
                     /score="38.4"
                     /tool="antismash"
                     /translation="AYNLPQVVMLEGALDVAKISLAFNQLLARHENLRTFF"
     CDS_motif       1658..1723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0004"
                     /evalue="2.30E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="573"
                     /protein_start="551"
                     /score="26.6"
                     /tool="antismash"
                     /translation="VHHIIMDGVSENILINDFMALY"
     CDS_motif       1754..1786
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0005"
                     /evalue="1.50E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="594"
                     /protein_start="583"
                     /score="14.4"
                     /tool="antismash"
                     /translation="QYKDFAEWQQE"
     CDS_motif       2045..2134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0006"
                     /evalue="5.50E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="710"
                     /protein_start="680"
                     /score="50.8"
                     /tool="antismash"
                     /translation="DVVVGTPVAGRHNSDVEQVMGMFVNTLPLR"
     CDS_motif       2186..2302
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0007"
                     /evalue="2.70E-12"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="766"
                     /protein_start="727"
                     /score="39.0"
                     /tool="antismash"
                     /translation="AKTLSCFDNQDYQYEALISDLALLRDAGRNPLFDAMFVF"
     aSDomain        2639..3754
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34435_AMP-binding.1"
                     /evalue="2.10E-110"
                     /label="B5D63_RS34435_AMP-binding.1"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="1250"
                     /protein_start="878"
                     /score="361.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQQAQQTPDHIAVEFNEERVTYRQLNHRSGQLARHLVHHGVAPG
                     DIVGLMMERSTDLIVGMLGIMKAGGAYLPLDATYPEEHIRNMLEECRVKTVLTEIPHHE
                     EAPLHALPEVTAAHTAYIIYTSGSTGKPKGVMVPHRPVVNLAWSQRRTFQITEAEKILQ
                     FSTICFDASVEQIWLALLSGATLVMVSREVILDNALFNQYLRDHAVTHLHATPSFLESV
                     AWEDVSALKRIIAGGEACPVTLAEKCGGVAAFYNEYGPTETTVTSIEYAVTGPMPDKTY
                     VPIGRPVHNTRVYILGEQLELLPAGARGKLYIGGDGLASGYVNDPELTARKFLWHPLLP
                     EERIYDTGDYARWLPDGQLEFLGRADEQIKIR"
     CDS_motif       2825..2866
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0008"
                     /evalue="1.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="954"
                     /protein_start="940"
                     /score="18.1"
                     /tool="antismash"
                     /translation="LGIMKAGGAYLPLD"
     CDS_motif       2996..3055
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0009"
                     /evalue="3.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="1017"
                     /protein_start="997"
                     /score="34.6"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMVPH"
     CDS_motif       3548..3637
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0010"
                     /evalue="8.80E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="1211"
                     /protein_start="1181"
                     /score="43.6"
                     /tool="antismash"
                     /translation="PAGARGKLYIGGDGLASGYVNDPELTARKF"
     CDS_motif       3719..3781
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34435_0011"
                     /evalue="3.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="1259"
                     /protein_start="1238"
                     /score="35.1"
                     /tool="antismash"
                     /translation="FLGRADEQIKIRGYRVELGEI"
     aSDomain        4073..4279
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34435_PCP.2"
                     /evalue="1.20E-20"
                     /label="B5D63_RS34435_PCP.2"
                     /locus_tag="B5D63_RS34435"
                     /protein_end="1425"
                     /protein_start="1356"
                     /score="65.4"
                     /tool="antismash"
                     /translation="MLANIWSEVLSLNREKIGANSTFFELGGNSLLLIKLQVRMKERLG
                     INVAVAELFTYSSVAALAAFLDNG"
     gene            4376..>5601
                     /locus_tag="B5D63_RS34440"
                     /old_locus_tag="SAMN04488128_1212"
     CDS             4376..>5601
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (8-406). E-value:
                     1.3e-135. Score: 444.5. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34440_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012337.5"
                     /locus_tag="B5D63_RS34440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1212"
                     /product="polyketide synthase"
                     /protein_id="WP_143313386.1"
                     /sec_met_domain="hyb_KS (E-value: 2.5e-142, bitscore:
                     461.7, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-69, bitscore:
                     221.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKYNGVEIAVIGMAGQFPGAENVNEFWRNLQSGKESITFFSREE
                     LMAAGEDEAIADDPSYVNANARLNGKAGFDAAFFGYRPDEATIMDPQIRLFHQYCWAAM
                     EDAGYDVTTYPDKIGLFAGGSPDNNWENYTILRNGQQKRVDEYSASQLRNITFLCSRVA
                     YQLNLQGPSVFVNTACSTSLVAVQRACMSLLLRECKMAMAGGITLNSFSGRGYLYQEGM
                     INSKDGHCRAFDAGANGTVGGEGGGVIVLKRLAEAIAEGDHIYAVIRGSGINNDGHDKM
                     SFTAPGVNGQYNAVLKAVNMAGIAPDSISFVETHGTGTHLGDPIEIEALRRVFGNSSRQ
                     YCALGAVKTNIGHLDAAAGIAGFIKTVLCLHHRQLVPTLHYQRPNPAINFADGPFYVNT
                     TLKEWSHNG"
     aSDomain        4400..5593
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34440_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.30E-135"
                     /label="B5D63_RS34440_PKS_KS.1"
                     /locus_tag="B5D63_RS34440"
                     /protein_end="406"
                     /protein_start="8"
                     /score="444.5"
                     /tool="antismash"
                     /translation="IAVIGMAGQFPGAENVNEFWRNLQSGKESITFFSREELMAAGEDE
                     AIADDPSYVNANARLNGKAGFDAAFFGYRPDEATIMDPQIRLFHQYCWAAMEDAGYDVT
                     TYPDKIGLFAGGSPDNNWENYTILRNGQQKRVDEYSASQLRNITFLCSRVAYQLNLQGP
                     SVFVNTACSTSLVAVQRACMSLLLRECKMAMAGGITLNSFSGRGYLYQEGMINSKDGHC
                     RAFDAGANGTVGGEGGGVIVLKRLAEAIAEGDHIYAVIRGSGINNDGHDKMSFTAPGVN
                     GQYNAVLKAVNMAGIAPDSISFVETHGTGTHLGDPIEIEALRRVFGNSSRQYCALGAVK
                     TNIGHLDAAAGIAGFIKTVLCLHHRQLVPTLHYQRPNPAINFADGPFYVNTTLKEWSH"
     CDS_motif       4883..4930
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34440_0001"
                     /evalue="2.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="B5D63_RS34440"
                     /protein_end="185"
                     /protein_start="169"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GPSVFVNTACSTSLVA"
     CDS_motif       5306..5353
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34440_0002"
                     /evalue="9.20E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="B5D63_RS34440"
                     /protein_end="326"
                     /protein_start="310"
                     /score="14.3"
                     /tool="antismash"
                     /translation="FVETHGTGTHLGDPIE"
     CDS_motif       5408..5452
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34440_0003"
                     /evalue="3.70E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="B5D63_RS34440"
                     /protein_end="359"
                     /protein_start="344"
                     /score="12.8"
                     /tool="antismash"
                     /translation="GAVKTNIGHLDAAAG"
ORIGIN
        1 cgttctgctg aaagtgctgt cgcaggagta tccctcttta cagacgagcc atattgatgt
       61 gagtttgtcg gaagaagggt ggcagccgtt gctggccgcg gagatcaata caccggggaa
      121 cggcagggtg atatgcctgc gtcacggtcg tcgctggggg cggcattacg agcgtctgga
      181 aacatccgtg tctgcaatgc caggcggagg aatttacctg gtcaccggtg ggctgggcgg
      241 tttgggttat acattaagta aacgcttgct ggcagacaat gccgcgggcc tgatactgac
      301 gggccgggtg gcgttgccgc cgcgtgctgc ctgggatgcc ggtgacctgg aagcaggtgt
      361 gaaagcgcgt atagaaaaga tccgtgagct ggaatcacgg ggctgtcgtg tgctgtacag
      421 ccactgcgat ctcacggacg tagcagcggt acgggaactg gtggccagct cggaggctgt
      481 gctgggcggc cgtatcagcg gcgtggtcca tgcggcgggc atcgcggacg gggaaagcca
      541 tggtggtata gacacgctga cgcagcaaga ctatgaaaaa cagttcgggc ccaaagtgca
      601 gggactggaa gtattgcaga ccgtgttggg tgatcgtgcg cttgaatttt ttgccgctac
      661 ctcatctctc tctaccgtgc tgggggggat tggttttgga gcttatgctc ccgccaatgc
      721 ttacatggat gcctacatta cttccggggt aggtaccggc agcttaaaac attggataag
      781 catctgtttc gacggcctgg aatatggtga taaaaccggt ggtggtatta cgggcgggga
      841 actggcagag gtatggcgcc gcatcatgag cgtccgtcat ctgccgcagg tggtggtttc
      901 ggtgtccgat ctgcagctgc ggctgcagca atgggtcaac cgggaagtgg ctgttgccga
      961 aggcggggaa gccatggcag caggggatga taaggcttcg gaggatgata tcaccgcttc
     1021 actgatcggt ttatgggaac agttttttgg aaagcagggt attactgcgg aagatgattt
     1081 ttttgaaata ggcggtaact cattgaaggc gcttaccatg atggggcgca tacataagct
     1141 gttcaatgtg gaagtaccgg tgaaaacctt ttttgataat tccaccatta cattactggc
     1201 agcgcagatg aatacgctga tgtcggctgg caatgccggc cggaaggaat atacggctat
     1261 ccccagcgct ccgttaaagc catattatgc attgtcttcc gcacagaagc ggctttattt
     1321 cctgtatgaa atggacaaag actccattgc ctacaatctg ccgcaggtgg ttatgctgga
     1381 aggtgcatta gacgtggcga aaatcagcct cgccttcaat cagttgctgg cgcgtcatga
     1441 aaacctccgc accttttttg aggtggaaga cggcgttcct gtacagaaaa tagccgctcc
     1501 ggttacctgt caaatacctg tggtgaaggc aaccgccgaa gaagtgccgg cagtcattca
     1561 caattttatc cggccgtttg acctgcgcgc ggcgcctttg atcaggatgg cgctggtggc
     1621 catcggcagc cggcagcaca tactgatggt agatgtacat catatcatta tggacggggt
     1681 gtctgaaaat atccttatca atgattttat ggcattgtac caggaagaaa cgttgccccc
     1741 cctgcaactg cagtataaag attttgcaga atggcagcaa gaggttgcgt cccagccctg
     1801 gatgtcggta caacgggatt tctggatgcg tgaatttgaa gaggtgccca cccccctgga
     1861 gctgccatat gactacgccc ggcctgctgc taaagaccag gaaggccata tcatcagctt
     1921 tgatattgat accattctca ccggccattt gaaacaactg gcagaagcag aaaagaccac
     1981 actgttcatg gtattgctgg cagcatataa tatcctgctg gcaagggttt ccggacagga
     2041 tgacgtagtg gtgggcacgc cggtggccgg ccgtcacaac agtgatgtgg aacaggtaat
     2101 gggaatgttt gtgaatacgc tccctttaag aaaccaggtg tcaggcggaa gcagtttcag
     2161 ggaactattg gcggcggtaa aggcaaaaac gttgtcctgt tttgataacc aggactacca
     2221 gtatgaagcc ctgatcagcg acctggcgtt gttaagggac gccggccgaa acccgctttt
     2281 cgatgccatg tttgtgtttc agaactatga acaatctacc ctggaactgc cggggcttac
     2341 attaaagccc tatagtacgg gccacgcagt ggctaaattc gatatgacct tatctgcttt
     2401 tgaacacgac ggaaagcttt tactgagcat ggaatatgcg acgtcactgt ttaaagaagc
     2461 gaccatacaa cggtttgtta cctgttttgt caatatcctt acggcgatca ctgctcatcc
     2521 gcaggcattg ataaaagacc tggtgatcat tccggcggaa gaagcacacc ggctattgta
     2581 tgaatggaat aatacagcca ctgattaccc gtcagacaag agtcttgtgg agctgttcga
     2641 acagcaggcg cagcagaccc cggaccatat cgcagtggag ttcaacgaag agcgcgttac
     2701 ttaccggcag ttaaatcacc ggtccggcca acttgcccgt cacctggtac accatggcgt
     2761 agcgcccgga gatatcgtgg gactgatgat ggaacggtca accgatctga tcgtgggaat
     2821 gctgggcatt atgaaagcag gtggcgccta cctgccgctg gacgctacct atccggagga
     2881 gcatatccgg aacatgctgg aggaatgcag ggtgaagaca gtgttgacag aaatacctca
     2941 tcatgaagaa gcaccgcttc atgccttacc tgaagttaca gcagcgcaca ccgcttacat
     3001 aatttataca tccggctcca ctggtaaacc taaaggagtt atggtgccgc atcgcccggt
     3061 agtgaacctg gcctggtcgc aacgaaggac ctttcagatc accgaagcgg aaaagatcct
     3121 acagttctcc actatctgtt tcgatgcttc ggtggaacag atctggctgg cattgttgag
     3181 cggcgccacc ctggtgatgg tcagccgtga agtgatactg gacaacgcgc tgtttaatca
     3241 atacctgagg gaccatgcgg tcacgcactt gcatgccacg ccatccttcc tggagagcgt
     3301 cgcatgggag gatgtgtctg cgctgaaaag gatcattgcg ggcggggagg cctgccccgt
     3361 gacactcgca gagaaatgtg gcggagtggc tgctttctat aacgagtacg gccctacgga
     3421 aacgaccgta acgtccattg aatatgccgt taccggtccg atgcccgaca agacatatgt
     3481 ccctatcggc cgccccgtcc acaacaccag ggtttatatt ctgggagagc aactggaact
     3541 gttgccggca ggggccaggg ggaaacttta catcggcggc gatggcctgg catcaggcta
     3601 tgtcaacgac cccgaactga ctgcacgtaa gtttctgtgg catccgttat tgccggaaga
     3661 gcgcatctat gataccggcg attatgccag gtggctgccc gatgggcaac tggaattcct
     3721 ggggagggcc gatgagcaaa taaagatcag gggataccgt gtggagctgg gagagattgc
     3781 agcccgcctg cggcagcacg aggaagtaca ggatagtatc gtcattgctg accggcaggg
     3841 acagcatacc gtcctcaccg cctattatat tcctgttcac ggagccggta ttctctcgtt
     3901 ggatgcttat atgcgtgaac aattgccggc ctacatgata ccagcgcatt ttataaaaat
     3961 ggaacagttc ccggtgaacc gcaacggaaa gatagaccgg aaggcactgc cgttggtgga
     4021 aagcgctgcc ggagcggaat ttatatcgcc tttgggagac acggcggaaa tgctggctaa
     4081 tatctggtct gaggtcttgt cgctcaacag ggagaagatc ggcgctaaca gcactttttt
     4141 tgaactgggg ggaaattctc tcctgttaat aaaactgcag gtgcggatga aggaacgctt
     4201 agggatcaac gtcgctgtgg cggaactgtt tacctattct tctgttgcag cgctggcggc
     4261 atttcttgat aatggcaacg ttgccgtgga gcaattcgaa aaaacggtca gagaagaagt
     4321 ggaagggcta aaaaacatga tcgatatttt taaataagtg taatcccgga aaaatatgac
     4381 taaatacaat ggtgttgaaa ttgccgttat cggaatggca ggacagtttc caggtgctga
     4441 aaacgtaaat gaattctgga gaaacctcca atcgggaaag gaatccatca cttttttttc
     4501 cagagaggaa ctgatggctg cgggagaaga tgaggctatt gcagatgatc cgtcttatgt
     4561 gaacgcaaat gcccggctaa atggaaaagc cggctttgac gcggcgtttt ttggataccg
     4621 ccccgatgaa gcgacgatca tggaccccca gatccgtttg tttcaccagt actgctgggc
     4681 agcgatggaa gatgccgggt atgatgtgac cacctacccg gataaaatcg gattatttgc
     4741 cgggggctcg ccggacaata actgggaaaa ctatacgatc ctgcgcaacg ggcaacagaa
     4801 aagagtggat gaatattcgg cttcccagct tcgcaacatt accttcttgt gttcaagggt
     4861 tgcttaccag cttaatctgc aaggtccgtc agtatttgtg aacaccgctt gctctacttc
     4921 tctggtggcc gtacagcggg cgtgtatgag ccttttgcta cgggagtgta aaatggcgat
     4981 ggctggcggc attacgctca acagtttttc cgggagagga tatttgtatc aggagggaat
     5041 gattaattcc aaagacgggc attgccgcgc gtttgatgct ggcgccaacg gtaccgtggg
     5101 cggagaaggc ggcggggtga tagtactgaa acgcctggca gaagcgattg ctgaaggaga
     5161 tcatatctac gcggtgatca gaggcagtgg gatcaataat gatggccatg ataaaatgtc
     5221 gtttaccgcg ccgggtgtga acggacagta taatgcagtg ttaaaggccg tcaatatggc
     5281 cggcattgcg cctgatagca tcagttttgt ggagacgcat ggtacgggaa cgcaccttgg
     5341 cgacccgatc gagatagaag cgctgcggcg tgtttttggg aacagcagcc ggcagtattg
     5401 tgcgctgggc gccgtgaaga ccaatatcgg ccatctggac gctgctgcgg gcatagccgg
     5461 ttttatcaaa acggtattgt gcctgcatca ccgtcagctg gtgcctacgc ttcattatca
     5521 gcgtcccaac ccggcgatca attttgcaga tggccctttt tatgtaaata caacgctgaa
     5581 agaatggtct cataacggcc a
//
