LOCUS       NZ_FUWZ01000016        13342 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000016
VERSION     NZ_FUWZ01000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 13342
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..13342
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1236:>13342](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1237..>13342
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            <1..1224
                     /locus_tag="B5D63_RS34360"
                     /old_locus_tag="SAMN04488128_1161"
     CDS             <1..1224
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (0-249). E-value:
                     5.2e-81. Score: 263.9. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34360_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="B5D63_RS34360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1161"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_235021706.1"
                     /sec_met_domain="Condensation (E-value: 1.5e-59, bitscore:
                     189.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VARHESLRTVFKTVDGMPVQEILDIAACGFHLEETDLRAAAETVS
                     SVVASEQTTAFDLSQGPLIRARLLRTGASEYVFVLTLHHIITDGWSMEVIVGEVLRLYE
                     AYSSGEEALLPPLRLQYKDYACWQQERLQQESMAAHRAYWLSQLGGGIPRLNLPTDFAR
                     PAVWMPGAGIVSDSIHPDVYARMQALAGNWGVSLYNLLMAAAKVLLFRYTGDQEIVVGY
                     PVSLRSHAELETQVGFYLNTLALRTRLEHHYTYRNVVMAVRQSMLEASKHQEYPFDKVV
                     SGLRYTRDAGRAPLFDVVVVLQNLKVHRQEVNRMGEMEVTVLPFDNTTSSVDLRMEFIE
                     REDRFTVNFEYNLALFRRHTVRLLMDRFLSVLTQLAGSPDIPVATVGMEEDTTTTVEDL
                     KDHFSINF"
     source          1..13342
                     /db_xref="taxon:634771"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070509_116"
                     /organism="Chitinophaga eiseniae"
                     /strain="DSM 22224"
                     /type_material="type strain of Chitinophaga eiseniae"
     region          1..13342
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..13342
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)NC(CO)C(=O)CC(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="interleaved"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..13342
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[6895:11368](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      6896..11368
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     aSDomain        4..750
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34360_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.20E-81"
                     /label="B5D63_RS34360_Condensation_LCL.1"
                     /locus_tag="B5D63_RS34360"
                     /protein_end="249"
                     /protein_start="0"
                     /score="263.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIITDG"
                     /tool="antismash"
                     /translation="VARHESLRTVFKTVDGMPVQEILDIAACGFHLEETDLRAAAETVS
                     SVVASEQTTAFDLSQGPLIRARLLRTGASEYVFVLTLHHIITDGWSMEVIVGEVLRLYE
                     AYSSGEEALLPPLRLQYKDYACWQQERLQQESMAAHRAYWLSQLGGGIPRLNLPTDFAR
                     PAVWMPGAGIVSDSIHPDVYARMQALAGNWGVSLYNLLMAAAKVLLFRYTGDQEIVVGY
                     PVSLRSHAELETQVGFYLNTLALRTRL"
     aSModule        4..3648
                     /complete
                     /domains="nrpspksdomains_B5D63_RS34360_Condensation_LCL.1"
                     /domains="nrpspksdomains_B5D63_RS34365_AMP-binding.1"
                     /domains="nrpspksdomains_B5D63_RS34365_PCP.1"
                     /locus_tags="B5D63_RS34360"
                     /locus_tags="B5D63_RS34365"
                     /monomer_pairings="Tyr -> Tyr"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       247..312
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34360_0001"
                     /evalue="3.40E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="B5D63_RS34360"
                     /protein_end="103"
                     /protein_start="81"
                     /score="35.5"
                     /tool="antismash"
                     /translation="LHHIITDGWSMEVIVGEVLRLY"
     CDS_motif       361..399
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34360_0002"
                     /evalue="5.30E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34360"
                     /protein_end="132"
                     /protein_start="119"
                     /score="18.8"
                     /tool="antismash"
                     /translation="QYKDYACWQQERL"
     CDS_motif       652..741
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34360_0003"
                     /evalue="3.20E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34360"
                     /protein_end="246"
                     /protein_start="216"
                     /score="35.6"
                     /tool="antismash"
                     /translation="EIVVGYPVSLRSHAELETQVGFYLNTLALR"
     CDS_motif       790..909
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34360_0004"
                     /evalue="3.80E-13"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34360"
                     /protein_end="302"
                     /protein_start="262"
                     /score="41.7"
                     /tool="antismash"
                     /translation="RQSMLEASKHQEYPFDKVVSGLRYTRDAGRAPLFDVVVVL"
     misc_feature    1226..1235
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            1237..6906
                     /locus_tag="B5D63_RS34365"
                     /old_locus_tag="SAMN04488128_1162"
     CDS             1237..6906
                     /NRPS_PKS="Domain: AMP-binding (235-630). E-value: 2e-104.
                     Score: 341.4. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34365_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (737-804). E-value: 4.2e-22. Score:
                     70.1. Matches aSDomain: nrpspksdomains_B5D63_RS34365_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (833-1126). E-value:
                     3.6e-97. Score: 316.9. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34365_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1292-1679). E-value:
                     2.1e-104. Score: 341.3. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34365_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1787-1856). E-value: 1.4e-17.
                     Score: 55.6. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34365_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="B5D63_RS34365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1162"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_078673425.1"
                     /sec_met_domain="PP-binding (E-value: 5.3e-20, bitscore:
                     60.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-71, bitscore:
                     229.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-116, bitscore:
                     376.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQVSEQQSPLTIEPPFVFRERAATGAHHSFAGYTGGIPATVAT
                     TLLQITREDASALYVCMFGTLSIVLKKLLQADRITLGMPLMAGQTGREERIMVSVNVPD
                     TSSLRQLLNSVNHALKTAYTLPVAHRTLSNVLLAYPEIHAGVQTADDDLRIDICREADK
                     ISLHFNYDQQAFTGDFIAQLFRQWVQVLSYAGELDCMVKNMTLLDAAQREMIVHGFNRT
                     ARERHDERTVISLFEKNVSATPDAIALAYGDTMLTYDKLNNEVNKLAGYLKNHYRPGAD
                     EIVALMLPPSDKWVVAMLAILKTGAAYLPLDTALPAKRKAWILADAGVKLLLTDIDQLA
                     EQPDYQGDIFLLDSGQQHLTETPEEPVTAILPGSLAYVIYTSGTTGTPKGVMLEHGGLL
                     NMIQCQIRQFDIRASDKVLQFASPSFDAAVSEMFMALCAGARLVMADRPALKDAQLFSA
                     LLQQQQITVVTLPPSYLGALPWDTFLSLRVIISAGEKLHTAAARYLSRHLSFYNAYGPT
                     ECTVCTTIHLIQPDMDDDEMESIGTPIDNVQVYILGAHQEVLPVGVPGDIYIGGSGLAR
                     GYLHQPALTAARFITTPWPDVPGERLYYTGDTGKWLANGKIVYTGRRDDQVKVRGYRVE
                     PAEVAAVVMASGLVQQCEVMGIEQAGGQLQLTAFVVPATVFDQEKLTSYVAERLPGYMV
                     PAVWRSLPALPVTHNGKADRKKLQEMAPLPEEDTLVVAASNAIEAKLADIWKEVLELDH
                     VSVTSDFFRSGGDSLQAIRLLAIIREHFTADITINDLFQYTSIRQLADYIRISGGDDNA
                     MQATPASYLPPLLPAAESRTGALPLSFGQERLWLIHQLTGSAHYHLPVMLRLKGTTDTV
                     CLEKAIRAIADRHEILRTVYLENDGEVRQVMMPPGKWQFDFCGELPAGQDLSGYVNAFS
                     SRAFALTTDHMLRAALIITGTDERLLIIVLHHIAADGWSVPILVREFMENYRLLKEGGD
                     ITLPPLPVQYADYAIWQRKQEGQEYLVRQLAYWEKKLDGITPVMLPVDHPRAPVAQHAG
                     KALYFYFDVGLKHQLEQLSHEEGVTLFMTLLAVFNVLLYRYSGQEDLCTGTAVAGRQQR
                     VAEQLVGFFINMLVIRIQLSGAGSFREVLATVKQNTLEAFDHQDIPFELVVDRLMKVRD
                     DSRHPLFQAAFILQNQPEAPAIVLDGLDVKPEEPASATSRFDLGFEVTATDTVFKLRVE
                     YNTALFEEDTVHRLAAHYGQLLKAVVASPEQQVGHLNMLCDADSRQLLNEFNDTAHVFP
                     ADRILPVLFEEQAAARPEAVALIYNSIEYTFRALDVAANRLATCLRTRYGVNRGNLVGV
                     QLPRSEWQIIALLAVLKTGAAYVPLDPAFPVPRVQEIADDCHWPLLITEAWLAAYQPEA
                     SQYSDAPLPCQGTPEDLMYVIFTSGSTGKPKGVMMPYYGVMNRLWWMWEHYGFSREDVI
                     LQKTNFTFDVSVWEIFMPLCMGARMVLCSQEEVLSPDRLQALIVAHHVSCLHFVPGMLD
                     VFIDALPETGMPAGMEGLRLVFASGEALRPETVQRWYRHTAVTLHNLYGPTEAAVDVTY
                     YETGAADTRIPIGRPIWNTAIRVLNAEGGLVPPGGTGEICIAGAGLARGYLNNPELTAL
                     RFVPDPFVPGSKIYRTGDYGRWLPDGQLEYLGRKDGQVKIRGFRIETGEIEAAINSLPY
                     VTTCAVVALPDAGGQTELVAYLVSHQEPDITSLRRDLAVILPAYMLPARYVRLSEMPLT
                     TSGKTDKTRLPALAGQQLAGGGDYVPPSGDTEQQLVKIWQTLLGDVPIGTTQPFFELGG
                     NSIKLMKMVAMIRKQFHKDLPVVKAFGLPAIRDLAQYLEQTGEELQPSTADAPYVSVDI
                     MKNSLLLINKFTDEA"
     aSDomain        1942..3126
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34365_AMP-binding.1"
                     /evalue="2.00E-104"
                     /label="B5D63_RS34365_AMP-binding.1"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="630"
                     /protein_start="235"
                     /score="341.4"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEKNVSATPDAIALAYGDTMLTYDKLNNEVNKLAGYLKNHYRPGA
                     DEIVALMLPPSDKWVVAMLAILKTGAAYLPLDTALPAKRKAWILADAGVKLLLTDIDQL
                     AEQPDYQGDIFLLDSGQQHLTETPEEPVTAILPGSLAYVIYTSGTTGTPKGVMLEHGGL
                     LNMIQCQIRQFDIRASDKVLQFASPSFDAAVSEMFMALCAGARLVMADRPALKDAQLFS
                     ALLQQQQITVVTLPPSYLGALPWDTFLSLRVIISAGEKLHTAAARYLSRHLSFYNAYGP
                     TECTVCTTIHLIQPDMDDDEMESIGTPIDNVQVYILGAHQEVLPVGVPGDIYIGGSGLA
                     RGYLHQPALTAARFITTPWPDVPGERLYYTGDTGKWLANGKIVYTGRRDDQVKVR"
     CDS_motif       2131..2172
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0001"
                     /evalue="3.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="312"
                     /protein_start="298"
                     /score="16.9"
                     /tool="antismash"
                     /translation="LAILKTGAAYLPLD"
     CDS_motif       2362..2421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0002"
                     /evalue="8.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="395"
                     /protein_start="375"
                     /score="33.7"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGTPKGVMLEH"
     CDS_motif       2776..2805
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0003"
                     /evalue="2.30E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="523"
                     /protein_start="513"
                     /score="10.6"
                     /tool="antismash"
                     /translation="YGPTECTVCT"
     CDS_motif       2914..3003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0004"
                     /evalue="3.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="589"
                     /protein_start="559"
                     /score="51.2"
                     /tool="antismash"
                     /translation="PVGVPGDIYIGGSGLARGYLHQPALTAARF"
     CDS_motif       3091..3153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0005"
                     /evalue="1.80E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="639"
                     /protein_start="618"
                     /score="32.8"
                     /tool="antismash"
                     /translation="YTGRRDDQVKVRGYRVEPAEV"
     aSDomain        3448..3648
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34365_PCP.1"
                     /evalue="4.20E-22"
                     /label="B5D63_RS34365_PCP.1"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="804"
                     /protein_start="737"
                     /score="70.1"
                     /tool="antismash"
                     /translation="EAKLADIWKEVLELDHVSVTSDFFRSGGDSLQAIRLLAIIREHFT
                     ADITINDLFQYTSIRQLADYIR"
     aSDomain        3736..4614
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34365_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.60E-97"
                     /label="B5D63_RS34365_Condensation_LCL.1"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1126"
                     /protein_start="833"
                     /score="316.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="ALPLSFGQERLWLIHQLTGSAHYHLPVMLRLKGTTDTVCLEKAIR
                     AIADRHEILRTVYLENDGEVRQVMMPPGKWQFDFCGELPAGQDLSGYVNAFSSRAFALT
                     TDHMLRAALIITGTDERLLIIVLHHIAADGWSVPILVREFMENYRLLKEGGDITLPPLP
                     VQYADYAIWQRKQEGQEYLVRQLAYWEKKLDGITPVMLPVDHPRAPVAQHAGKALYFYF
                     DVGLKHQLEQLSHEEGVTLFMTLLAVFNVLLYRYSGQEDLCTGTAVAGRQQRVAEQLVG
                     FFINMLVIRIQL"
     aSModule        3736..6804
                     /complete
                     /domains="nrpspksdomains_B5D63_RS34365_Condensation_LCL.1"
                     /domains="nrpspksdomains_B5D63_RS34365_AMP-binding.2"
                     /domains="nrpspksdomains_B5D63_RS34365_PCP.2"
                     /locus_tags="B5D63_RS34365"
                     /monomer_pairings="Ser -> Ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3796..3912
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0006"
                     /evalue="1.30E-13"
                     /label="C2_DCL_024-062"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="892"
                     /protein_start="853"
                     /score="43.2"
                     /tool="antismash"
                     /translation="AHYHLPVMLRLKGTTDTVCLEKAIRAIADRHEILRTVYL"
     CDS_motif       4114..4179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0007"
                     /evalue="4.30E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="981"
                     /protein_start="959"
                     /score="35.2"
                     /tool="antismash"
                     /translation="LHHIAADGWSVPILVREFMENY"
     CDS_motif       4228..4263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0008"
                     /evalue="2.80E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1009"
                     /protein_start="997"
                     /score="16.6"
                     /tool="antismash"
                     /translation="QYADYAIWQRKQ"
     CDS_motif       4516..4605
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0009"
                     /evalue="7.60E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1123"
                     /protein_start="1093"
                     /score="34.4"
                     /tool="antismash"
                     /translation="DLCTGTAVAGRQQRVAEQLVGFFINMLVIR"
     CDS_motif       4654..4773
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0010"
                     /evalue="5.00E-16"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1179"
                     /protein_start="1139"
                     /score="51.0"
                     /tool="antismash"
                     /translation="KQNTLEAFDHQDIPFELVVDRLMKVRDDSRHPLFQAAFIL"
     aSDomain        5113..6273
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34365_AMP-binding.2"
                     /evalue="2.10E-104"
                     /label="B5D63_RS34365_AMP-binding.2"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1679"
                     /protein_start="1292"
                     /score="341.3"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="FEEQAAARPEAVALIYNSIEYTFRALDVAANRLATCLRTRYGVNR
                     GNLVGVQLPRSEWQIIALLAVLKTGAAYVPLDPAFPVPRVQEIADDCHWPLLITEAWLA
                     AYQPEASQYSDAPLPCQGTPEDLMYVIFTSGSTGKPKGVMMPYYGVMNRLWWMWEHYGF
                     SREDVILQKTNFTFDVSVWEIFMPLCMGARMVLCSQEEVLSPDRLQALIVAHHVSCLHF
                     VPGMLDVFIDALPETGMPAGMEGLRLVFASGEALRPETVQRWYRHTAVTLHNLYGPTEA
                     AVDVTYYETGAADTRIPIGRPIWNTAIRVLNAEGGLVPPGGTGEICIAGAGLARGYLNN
                     PELTALRFVPDPFVPGSKIYRTGDYGRWLPDGQLEYLGRKDGQVKIR"
     CDS_motif       5302..5343
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0011"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1369"
                     /protein_start="1355"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LAVLKTGAAYVPLD"
     CDS_motif       5494..5550
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0012"
                     /evalue="3.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1438"
                     /protein_start="1419"
                     /score="28.7"
                     /tool="antismash"
                     /translation="MYVIFTSGSTGKPKGVMMP"
     CDS_motif       5938..5961
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0013"
                     /evalue="3.40E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1575"
                     /protein_start="1567"
                     /score="4.4"
                     /tool="antismash"
                     /translation="YGPTEAAV"
     CDS_motif       6067..6156
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0014"
                     /evalue="8.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1640"
                     /protein_start="1610"
                     /score="50.0"
                     /tool="antismash"
                     /translation="PPGGTGEICIAGAGLARGYLNNPELTALRF"
     CDS_motif       6238..6303
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34365_0015"
                     /evalue="8.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1689"
                     /protein_start="1667"
                     /score="37.0"
                     /tool="antismash"
                     /translation="YLGRKDGQVKIRGFRIETGEIE"
     aSDomain        6598..6804
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34365_PCP.2"
                     /evalue="1.40E-17"
                     /label="B5D63_RS34365_PCP.2"
                     /locus_tag="B5D63_RS34365"
                     /protein_end="1856"
                     /protein_start="1787"
                     /score="55.6"
                     /tool="antismash"
                     /translation="EQQLVKIWQTLLGDVPIGTTQPFFELGGNSIKLMKMVAMIRKQFH
                     KDLPVVKAFGLPAIRDLAQYLEQT"
     gene            6896..11368
                     /locus_tag="B5D63_RS34370"
                     /old_locus_tag="SAMN04488128_1163"
     CDS             6896..11368
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (11-436). E-value:
                     5.6e-153. Score: 501.7. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34370_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (532-815). E-value: 2.7e-92.
                     Score: 301.2. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34370_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1130-1308). E-value: 2.7e-44.
                     Score: 143.2. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34370_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1404-1472). E-value: 8.7e-22.
                     Score: 69.1. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34370_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.5"
                     /locus_tag="B5D63_RS34370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1163"
                     /product="type I polyketide synthase"
                     /protein_id="WP_078673426.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.7e-67, bitscore:
                     215.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1.2e-159, bitscore:
                     519.8, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.8e-93, bitscore: 301.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.9e-39, bitscore:
                     123.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-17, bitscore:
                     51.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHNQPYTGLEIAIIGMACRFPGASCWQEFWYNLTNGVESVRFYT
                     DEDLAAAGVAPQEIARPDFVKADAVLEHKTRFDAAFFGYRPEEASVLNPMHRIFHECVW
                     EALEDAGYDPATVKSGIGLYAGGGNDLNWRVYSMLQQNNREVDSFTLSQLNNKDYLSAL
                     LSYKLNLRGPAFTVNTACSTSLVAINLACKSLLMGETGMALAGGVSLNTRQRKGYFYQE
                     GMIDSRDGHCRAFDALASGAVGGEGAGVVVLKRLQDAVRDRDHIYAVIKGSAINNDGNR
                     KVGFTAPSIEGQADCIRRALAMADTAPSGISYVEAHGTGTRLGDPIEVEALNTAFNRDR
                     SHSCALGSVKTNIGHLDTAAGVAGLIKTALSLKFKMLPPTLHFQSPNPEIDFEGGPFYV
                     NARLQPWPAADDTPRRAGVSSFGIGGTNAHAVLEEAPATTTAAEGRPWKLFTVSARTPV
                     SVCRYLEKIKAFLQQELRPALADMSFTLQTGRRHFPYRYAFAYQHLEDLLHKLDNIPAE
                     AAIRQTAANKPLTVFMFPGQGSQYNGMAQTLYEQEPFIKDILDRGFGIIRQLTGKSLQE
                     VWFAASGTEINRTLYAQPAIFLLEYAMAKQLMAWGVQPDYMIGHSIGELVAACVSGVFS
                     FEDALKIVVKRAALMDGLPAGSMISVSLSRQEADALLNEHVCLAAVNAPEQLVLSGPPD
                     AMQQATAQLERSGTPHVRLHTSHAFHSAMLDPVLAEFRAALDGITPGEIKIPFVSNVTG
                     EWITAAEATSPEYWSRHMRETVQLATGIQTIMATSTDICFIEAGAGHILSGLLKQQLSG
                     DTHIVAIPLVPAAREHLPDGQMLGNAIAQLWMNGISIDWQCYYREETRRRVPLPVYAFE
                     QTTYPVEVDPFKLGNRYLSAPKKNGWHHWIYYPVWKSSILLPATGKIKSFLFLSGGTAW
                     ETALVGQLRTAGHEVIQVVADTAFRQVDGKMYFMDPADKGQFGLLSAALRQEGVHFTDI
                     LYGWAAGAMDEALVLEAQNRTIHQCYFALAHLIQALQDGGQLNNTHVFLLTDHLFNIHH
                     TENSRYSQALAVGLLNALHQELPVSSSHIDIDSRATLSGLVLELGQESHQERTVAWRGH
                     SRWVSVYQQNETPLPQRQPVKKNGVYLVTGGLGKVGFLLARHLVGTCQAKVVLTGRRNV
                     EHTDENDEWNIRLKQLQAMGTAVYYRCDAADYDALETTVSHVKATLGPVLGVIHAAGNI
                     DRRYFELTEDMSVENTLAVLRPKVDGIRNLTRVFEKESPDFVWITSSLASVLGGIGFGA
                     YAAANLFMDHYISSRLQQHPSWKCIGLSEMALDASEEAAEARQERKALLPAELIALFEW
                     SAGTPGIPVIWQTAQGLGERLHNTYHAPRETAAILPGAAAAAAIQQRPALSTVFVPAAT
                     STEQILSQIMEQYFGFTGIGVDDDFFELGGDSLKAMILLKRIRQALDVQITVHDFFEAR
                     TIRQLATGIDNRLWLQAGENPENAFISII"
     aSDomain        6929..8203
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34370_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="5.60E-153"
                     /label="B5D63_RS34370_PKS_KS.1"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="436"
                     /protein_start="11"
                     /score="501.7"
                     /tool="antismash"
                     /translation="IAIIGMACRFPGASCWQEFWYNLTNGVESVRFYTDEDLAAAGVAP
                     QEIARPDFVKADAVLEHKTRFDAAFFGYRPEEASVLNPMHRIFHECVWEALEDAGYDPA
                     TVKSGIGLYAGGGNDLNWRVYSMLQQNNREVDSFTLSQLNNKDYLSALLSYKLNLRGPA
                     FTVNTACSTSLVAINLACKSLLMGETGMALAGGVSLNTRQRKGYFYQEGMIDSRDGHCR
                     AFDALASGAVGGEGAGVVVLKRLQDAVRDRDHIYAVIKGSAINNDGNRKVGFTAPSIEG
                     QADCIRRALAMADTAPSGISYVEAHGTGTRLGDPIEVEALNTAFNRDRSHSCALGSVKT
                     NIGHLDTAAGVAGLIKTALSLKFKMLPPTLHFQSPNPEIDFEGGPFYVNARLQPWPAAD
                     DTPRRAGVSSFGIGGTNAHAVLEEAP"
     aSModule        6929..11311
                     /complete
                     /domains="nrpspksdomains_B5D63_RS34370_PKS_KS.1"
                     /domains="nrpspksdomains_B5D63_RS34370_PKS_AT.1"
                     /domains="nrpspksdomains_B5D63_RS34370_PKS_KR.1"
                     /domains="nrpspksdomains_B5D63_RS34370_PCP.1"
                     /locus_tags="B5D63_RS34370"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       7409..7456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0001"
                     /evalue="7.90E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="187"
                     /protein_start="171"
                     /score="18.0"
                     /tool="antismash"
                     /translation="GPAFTVNTACSTSLVA"
     CDS_motif       7832..7879
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0002"
                     /evalue="9.20E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="328"
                     /protein_start="312"
                     /score="14.3"
                     /tool="antismash"
                     /translation="YVEAHGTGTRLGDPIE"
     CDS_motif       7934..7978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0003"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="361"
                     /protein_start="346"
                     /score="11.4"
                     /tool="antismash"
                     /translation="GSVKTNIGHLDTAAG"
     CDS_motif       8486..8542
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0004"
                     /evalue="2.70E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="549"
                     /protein_start="530"
                     /score="22.7"
                     /tool="antismash"
                     /translation="VFMFPGQGSQYNGMAQTLY"
     aSDomain        8492..9340
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34370_PKS_AT.1"
                     /evalue="2.70E-92"
                     /label="B5D63_RS34370_PKS_AT.1"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="815"
                     /protein_start="532"
                     /score="301.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFPGQGSQYNGMAQTLYEQEPFIKDILDRGFGIIRQLTGKSLQEV
                     WFAASGTEINRTLYAQPAIFLLEYAMAKQLMAWGVQPDYMIGHSIGELVAACVSGVFSF
                     EDALKIVVKRAALMDGLPAGSMISVSLSRQEADALLNEHVCLAAVNAPEQLVLSGPPDA
                     MQQATAQLERSGTPHVRLHTSHAFHSAMLDPVLAEFRAALDGITPGEIKIPFVSNVTGE
                     WITAAEATSPEYWSRHMRETVQLATGIQTIMATSTDICFIEAGAGHILSGLLKQQLSGD
                     TH"
     CDS_motif       8672..8707
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0005"
                     /evalue="5.40E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="604"
                     /protein_start="592"
                     /score="9.9"
                     /tool="antismash"
                     /translation="QPAIFLLEYAMA"
     CDS_motif       8726..8845
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0006"
                     /evalue="1.70E-25"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="650"
                     /protein_start="610"
                     /score="81.4"
                     /tool="antismash"
                     /translation="GVQPDYMIGHSIGELVAACVSGVFSFEDALKIVVKRAALM"
     CDS_motif       8930..8968
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0007"
                     /evalue="2.60E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="691"
                     /protein_start="678"
                     /score="11.1"
                     /tool="antismash"
                     /translation="AAVNAPEQLVLSG"
     CDS_motif       9191..9223
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0008"
                     /evalue="6.20E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="776"
                     /protein_start="765"
                     /score="13.2"
                     /tool="antismash"
                     /translation="YWSRHMRETVQ"
     aSDomain        10286..10819
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34370_PKS_KR.1"
                     /evalue="2.70E-44"
                     /label="B5D63_RS34370_PKS_KR.1"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="1308"
                     /protein_start="1130"
                     /score="143.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLVTGGLGKVGFLLARHLVGTCQAKVVLTGRRNVEHTDENDEW
                     NIRLKQLQAMGTAVYYRCDAADYDALETTVSHVKATLGPVLGVIHAAGNIDRRYFELTE
                     DMSVENTLAVLRPKVDGIRNLTRVFEKESPDFVWITSSLASVLGGIGFGAYAAANLFMD
                     HYISSRLQQHPSWKC"
     CDS_motif       10289..10387
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0009"
                     /evalue="2.60E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="1164"
                     /protein_start="1131"
                     /score="29.7"
                     /tool="antismash"
                     /translation="VYLVTGGLGKVGFLLARHLVGTCQAKVVLTGRR"
     CDS_motif       10688..10792
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34370_0010"
                     /evalue="2.90E-12"
                     /label="PKSI-KR_m4"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="1299"
                     /protein_start="1264"
                     /score="39.1"
                     /tool="antismash"
                     /translation="DFVWITSSLASVLGGIGFGAYAAANLFMDHYISSR"
     aSDomain        11108..11311
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34370_PCP.1"
                     /evalue="8.70E-22"
                     /label="B5D63_RS34370_PCP.1"
                     /locus_tag="B5D63_RS34370"
                     /protein_end="1472"
                     /protein_start="1404"
                     /score="69.1"
                     /tool="antismash"
                     /translation="EQILSQIMEQYFGFTGIGVDDDFFELGGDSLKAMILLKRIRQALD
                     VQITVHDFFEARTIRQLATGIDN"
     gene            11388..>13342
                     /locus_tag="B5D63_RS34375"
                     /old_locus_tag="SAMN04488128_1164"
     CDS             11388..>13342
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (70-369). E-value:
                     9e-101. Score: 328.7. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34375_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="B5D63_RS34375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1164"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_143313367.1"
                     /sec_met_domain="Condensation (E-value: 6.8e-81, bitscore:
                     259.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-28, bitscore:
                     87.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHELLKKLREQHIQIVLEDDNLRISSAAPIPTAIANAIREHKAAL
                     VQYLKNGLQETPAAATIPVAPESRGYALSSVQRRMWVLSQYQEGNLAYNMPAAYLLEGE
                     PDVARLERAFDLLIARHEILRTAFRVDDQGDIRQYIESSPQKFRIAPEDLRGAEEQRAQ
                     IDERIRQAHIIPFDLSSGPLLRAGLYRLSEKSWLFVYVMHHITGDGWSMGVLIRELMQL
                     YNTAETNDGLSLLPLRIHYKDYAAWQQARLADAGMEPCRKYWLEQLAGEIPVLQLPADN
                     ARPAIKTYHGAAIQQRLDPEVFARFRALVQEQGATLFMGLQAAVNILLYWYSGQEDIIT
                     GTPIAGRDHPELEDQIGVYINTLALRVRCQAEDTYLQLLSKVRQVTLNAYRYQSYPFDE
                     LVDELQLRRDMSRNPLFDVMVSLQNNDINLAGDHRMGSLAVSRYPDGQNIFCKFDLTFD
                     FIETAGTLQMTIEYNTDLYRSSTIDLMMGHLRQLITGITASPSTVIRELDLLTEKERQQ
                     LLSDFNNTEGDYERDKTIVALFRRQALLRPEETAVVFEDSALTYRELDERSDRVARLLT
                     EQLQVQPGALVALLTERSVHLMAGMLGILKAGAAYVPLDPAYPAERISYVLEDCGARVL
                     VAGEGTALPAGYDGAVL"
     aSDomain        11598..12494
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34375_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.00E-101"
                     /label="B5D63_RS34375_Condensation_LCL.1"
                     /locus_tag="B5D63_RS34375"
                     /protein_end="369"
                     /protein_start="70"
                     /score="328.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHITGDG"
                     /tool="antismash"
                     /translation="YALSSVQRRMWVLSQYQEGNLAYNMPAAYLLEGEPDVARLERAFD
                     LLIARHEILRTAFRVDDQGDIRQYIESSPQKFRIAPEDLRGAEEQRAQIDERIRQAHII
                     PFDLSSGPLLRAGLYRLSEKSWLFVYVMHHITGDGWSMGVLIRELMQLYNTAETNDGLS
                     LLPLRIHYKDYAAWQQARLADAGMEPCRKYWLEQLAGEIPVLQLPADNARPAIKTYHGA
                     AIQQRLDPEVFARFRALVQEQGATLFMGLQAAVNILLYWYSGQEDIITGTPIAGRDHPE
                     LEDQIGVYINTLALRVRC"
     CDS_motif       11661..11774
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34375_0001"
                     /evalue="2.90E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="B5D63_RS34375"
                     /protein_end="129"
                     /protein_start="91"
                     /score="61.5"
                     /tool="antismash"
                     /translation="AYNMPAAYLLEGEPDVARLERAFDLLIARHEILRTAFR"
     CDS_motif       11991..12056
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34375_0002"
                     /evalue="7.40E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="B5D63_RS34375"
                     /protein_end="223"
                     /protein_start="201"
                     /score="37.6"
                     /tool="antismash"
                     /translation="MHHITGDGWSMGVLIRELMQLY"
     CDS_motif       12105..12143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34375_0003"
                     /evalue="1.80E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34375"
                     /protein_end="252"
                     /protein_start="239"
                     /score="14.1"
                     /tool="antismash"
                     /translation="HYKDYAAWQQARL"
     CDS_motif       12396..12485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34375_0004"
                     /evalue="1.30E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34375"
                     /protein_end="366"
                     /protein_start="336"
                     /score="43.2"
                     /tool="antismash"
                     /translation="DIITGTPIAGRDHPELEDQIGVYINTLALR"
     CDS_motif       12534..12653
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34375_0005"
                     /evalue="1.20E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34375"
                     /protein_end="422"
                     /protein_start="382"
                     /score="59.5"
                     /tool="antismash"
                     /translation="RQVTLNAYRYQSYPFDELVDELQLRRDMSRNPLFDVMVSL"
     CDS_motif       13191..13232
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34375_0006"
                     /evalue="1.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="B5D63_RS34375"
                     /protein_end="615"
                     /protein_start="601"
                     /score="21.3"
                     /tool="antismash"
                     /translation="LGILKAGAAYVPLD"
ORIGIN
        1 gtggctcggc atgagagcct ccgcactgtt tttaagacgg tagacggtat gccggtgcaa
       61 gaaatactgg atattgccgc ctgcggtttc cacctggaag aaacagatct gcgtgcggcg
      121 gccgagacgg tgagcagtgt ggtggcgtcg gaacaaacaa cggcatttga cttgtcacaa
      181 gggcctttga tacgggcaag actgctgcgt acgggtgcgt ctgaatatgt atttgtacta
      241 accctgcatc acattatcac cgatggctgg tcaatggaag tgatcgtggg agaggtgctg
      301 cgtttatacg aagcttatag cagcggggaa gaagcattgc tgccgccgtt acgtttacaa
      361 tacaaggact atgcctgctg gcagcaggag cggctgcagc aggagagcat ggccgcgcat
      421 cgtgcatact ggctctcaca gttgggtgga gggattcccc gtcttaacct gccaacggat
      481 tttgccagac ctgccgtatg gatgcccggg gcgggcattg tttcggatag catccatcct
      541 gatgtttatg cccggatgca ggcgctggca ggaaattggg gggtaagctt atacaacctg
      601 ctgatggctg ctgctaaagt gctcctgttc cggtatacag gagatcagga gattgtggtg
      661 gggtatcccg tttcgctgag gagtcatgcc gaactggaaa cgcaggtagg cttttatctg
      721 aatactttgg ccttgcgtac ccgccttgag caccattaca cttaccgcaa cgtggtgatg
      781 gctgtccgcc agtctatgct ggaggccagt aaacaccagg agtatccttt cgataaagtt
      841 gtttccgggc tgcgctatac aagagatgcc ggcagggcgc cactgtttga tgtggtggtc
      901 gtattacaga acctgaaggt gcaccggcag gaagttaacc gtatggggga aatggaggta
      961 acggtgcttc cttttgataa caccacgtca tcggtggacc tccgcatgga gtttattgag
     1021 cgggaagacc ggttcaccgt taattttgaa tataatctcg ctttgtttcg ccggcatacc
     1081 gtccggttac tgatggaccg tttcctttct gtactcacgc aactggcagg ctctcccgac
     1141 atacctgtcg ccacagttgg tatggaagaa gataccacca ctactgtgga ggatttgaaa
     1201 gaccattttt caataaattt ttaatcgttt tttgagatga ccgaacaagt atcggagcaa
     1261 cagtctccgc tgactattga acctccgttt gttttccggg aacgggctgc caccggggca
     1321 caccatagtt ttgccggcta tacaggcggg ataccggcta cggtagccac cacactgctg
     1381 cagattacga gagaagatgc ctctgccttg tacgtttgta tgtttggtac actcagcatc
     1441 gtattgaaga aactcctgca ggcggaccgt atcaccctgg gaatgccgtt aatggccggg
     1501 cagacaggca gggaagagcg tatcatggta agtgtgaatg tccctgacac cagttcgttg
     1561 cggcagctcc tgaatagcgt gaaccatgct ttaaagacgg cttatacgtt gccggtagca
     1621 caccggacgt tgtcaaacgt cctgctggcg tatccggaaa tccacgccgg tgttcagacc
     1681 gctgatgatg acctccgtat tgatatctgc agagaggcgg acaaaataag cctgcatttt
     1741 aattatgatc agcaagcctt caccggggac ttcatcgcac agctattccg gcagtgggtg
     1801 caggtgctct cgtatgccgg ggagttggac tgtatggtga aaaacatgac gctgctggat
     1861 gctgcacaac gggagatgat cgtgcacgga tttaaccgta ctgccaggga acggcatgac
     1921 gaacggaccg tgatctccct gtttgaaaaa aacgttagcg ccacacctga tgcgatagcc
     1981 cttgcatatg gtgatacaat gctcacctat gataagctga acaacgaagt caataaactg
     2041 gcgggttacc tgaaaaacca ctatcgtccg ggcgctgatg aaattgttgc gctgatgttg
     2101 ccgccttccg ataaatgggt agtcgccatg ctggccattc tgaaaaccgg cgccgcttac
     2161 ctgccgctgg acacagcgct gccggccaaa aggaaagcgt ggattttagc cgatgccggt
     2221 gttaaattac tgttgacaga catagaccag ctggcagaac agcccgatta ccagggggac
     2281 atctttttgc tggacagcgg ccagcaacat cttacggaaa ccccggaaga gccggtgacg
     2341 gccattctgc ctggttcact ggcctatgta atatacacca gcggtactac cggtacgccg
     2401 aaaggggtga tgctggaaca cggcggcttg ctgaatatga tacaatgcca gatccggcag
     2461 ttcgatatac gggcatccga caaagtgttg cagtttgcat ccccgtcctt cgatgccgcg
     2521 gtgtccgaaa tgtttatggc cctgtgcgcc ggcgcccggc tggtaatggc agacaggccg
     2581 gcgctgaaag atgcgcagct tttttccgca ttgctgcagc aacagcagat taccgtagtg
     2641 acattgccgc cttcctacct gggcgcgctg ccgtgggata ccttcctttc tctccgggtg
     2701 atcatcagtg cgggagagaa acttcatact gccgccgccc ggtatctgag ccgtcacctg
     2761 tctttttata acgcttacgg gcctacggag tgtacggtgt gtaccaccat ccatcttatt
     2821 cagcccgata tggacgacga tgaaatggaa agcatcggca cgccgataga taatgtacag
     2881 gtgtatatac tgggcgctca ccaggaggtg ttgccggtgg gcgtaccggg cgatatatat
     2941 atcggcggct ccggcctggc ccgcggatac ctgcatcagc cggcgctgac ggcagcgcgg
     3001 ttcattacaa cgccatggcc cgatgtgccg ggagagcggt tgtattacac cggcgatacc
     3061 ggtaaatggc tggccaacgg taaaatcgtt tataccggca gacgcgatga tcaggtaaag
     3121 gtccgtggtt acagggtaga gccggcagaa gtggctgccg tggtgatggc gagtggcctg
     3181 gtacagcaat gtgaggtgat ggggatagaa caggcgggcg gacagctgca actgactgct
     3241 tttgtggtgc cggcgacagt attcgaccag gagaaactga ccagctatgt ggccgaaagg
     3301 ctgccgggtt atatggtgcc tgcagtatgg cgctcgctcc ctgcattgcc cgttacccac
     3361 aacgggaagg cagacaggaa aaaactgcag gaaatggcgc ccttgccgga ggaagatacc
     3421 cttgttgttg ctgcttccaa tgccatagaa gcaaaactgg cggatatctg gaaagaggtg
     3481 ctggagctgg accatgtcag tgtgaccagc gattttttcc ggtccggtgg cgattccctg
     3541 caggcgatca ggctgctggc gatcatcagg gaacatttta ccgcggatat tactatcaat
     3601 gacctctttc aatataccag catccggcaa ctggctgatt atatcaggat atcaggggga
     3661 gatgataatg ccatgcaggc cacgccggct tcttatctgc cgccattgct gccggcagcg
     3721 gagagccgga caggcgcgct gcccttgtct ttcggacagg agcggctgtg gctcattcat
     3781 cagttgacag gcagcgcaca ttatcacctg ccggtgatgc ttcgtctgaa aggcactacg
     3841 gatacagtat gcctggagaa ggctatccgt gcgattgctg acaggcatga aatattgcgt
     3901 acggtctatc tcgaaaacga cggggaagtc cgccaggtga tgatgccacc cggtaagtgg
     3961 cagtttgatt tctgcggaga actaccggca gggcaggatt tgtccggcta tgtcaacgcc
     4021 ttttccagcc gcgcttttgc gctcacaacg gaccacatgc tgcgggcagc attgataata
     4081 acgggtacgg acgaacgatt gttgataatc gtattgcatc atattgcggc agacggttgg
     4141 tcggtaccga tactggtgcg cgaatttatg gaaaactacc gcctgctgaa agaaggtggc
     4201 gatatcacat taccgccctt gccggttcaa tatgcagatt atgccatctg gcaacggaaa
     4261 caggaagggc aggagtacct ggtacggcag cttgcctact gggaaaagaa actggacgga
     4321 ataacgccgg tgatgctgcc tgtggaccat ccccgtgccc cggtggccca acacgccggc
     4381 aaagccctgt atttttattt tgatgtaggc ttgaaacacc agctggaaca attatcccat
     4441 gaggagggtg ttaccttgtt catgacattg ctggctgtgt tcaacgtgtt gctgtaccgt
     4501 tacagcgggc aggaagacct ttgtacagga acggcggtag cgggcaggca gcagcgggtt
     4561 gcggaacagc tggtgggctt tttcatcaat atgctggtta tccgtattca actgtcaggt
     4621 gccggttctt tccgtgaagt gctggcaacg gtaaaacaaa atacgctgga agcgttcgat
     4681 caccaggata tcccgtttga actggtggtc gaccggttga tgaaagtgag agatgacagc
     4741 aggcatcccc tgttccaggc agcctttatt ctgcagaatc agccggaggc cccggctatt
     4801 gtcctggacg gcctggatgt taagccggaa gaaccggcca gcgccacttc ccggttcgat
     4861 ctcggctttg aggtcacagc gaccgatacc gtctttaaac tccgggttga atacaatacc
     4921 gcgctctttg aagaagatac cgtgcatagg ctggcagcgc actacgggca gctgctgaaa
     4981 gcggtagtgg cctcgccgga acagcaggtg ggacatttga atatgctgtg tgacgcagac
     5041 agccgtcagt tgctgaatga atttaacgat acggcgcacg tcttcccggc cgaccggata
     5101 ttgccggtgt tgtttgagga acaggctgcc gccaggccgg aagctgtcgc cctgatatat
     5161 aacagtatcg aatacacgtt tcgcgcactg gacgtggcgg ccaacaggtt ggcgacctgc
     5221 cttcgtaccc gctacggcgt taaccgggga aacctggtgg gcgttcagct gccccgcagc
     5281 gaatggcaga taatagcgtt gctggccgtg ctgaagaccg gagctgctta tgtgccgctg
     5341 gacccggcat tcccggtccc gagagtacag gaaatcgcgg acgactgtca ttggccgttg
     5401 ttgatcaccg aagcatggct ggctgcttac cagccggagg catcgcaata cagcgatgcg
     5461 ccattgccat gccagggcac gccggaagat ctgatgtatg tgatcttcac ctccggttcc
     5521 accggaaaac ccaagggagt gatgatgccc tattatggtg ttatgaacag gttgtggtgg
     5581 atgtgggagc actatgggtt cagcagggag gacgttatcc tgcaaaagac caatttcaca
     5641 tttgacgtgt ccgtatggga gatatttatg ccgctatgca tgggcgcccg catggtgctg
     5701 tgcagccagg aagaggtgtt gtcgcctgac cgtttacagg cgctgatcgt ggcacatcat
     5761 gtcagttgcc tgcattttgt tccgggcatg ctggacgtgt ttatcgatgc gctgccggaa
     5821 acgggtatgc ctgcggggat ggaaggcctg cggctggtat tcgccagcgg agaggcacta
     5881 cggccggaga cggtgcaacg ctggtaccgg catacggcgg taacgctgca taacctgtac
     5941 ggccctacgg aggcggcagt ggatgttacg tattatgaga ccggcgccgc cgatacccgc
     6001 attcccatag gccgtccgat ctggaacacg gccatccgtg tactcaatgc ggaaggaggg
     6061 ctggttcctc ccggcggcac cggtgagata tgcattgccg gtgcaggcct ggccagaggg
     6121 tatttgaaca accctgaact gacagccctg cggttcgtgc cggacccgtt cgttccggga
     6181 agtaaaattt accggacagg ggattatggc cgctggctgc ctgacggtca gctggaatac
     6241 ctgggcagaa aagatggaca ggttaaaata cggggttttc gtatcgaaac cggggagata
     6301 gaggcggcca tcaacagcct gccctatgtg actacctgcg cagtggtcgc gcttccggat
     6361 gccggcggac aaacggaatt ggtggcatac ctggtgagtc accaggagcc ggatatcacg
     6421 tcactgcgta gagaccttgc cgttatactg cccgcttata tgttgcctgc ccgctatgta
     6481 cggctatcgg aaatgccatt gaccaccagc gggaagacag ataaaacgcg cttgcctgcc
     6541 ctggccgggc aacagctggc cggaggcggt gactatgtac cgccatccgg agatactgaa
     6601 cagcagctgg taaaaatatg gcaaacgcta ctgggcgatg tgcccatcgg tacaacgcag
     6661 cctttcttcg agctgggtgg caattccatt aaactcatga agatggtggc catgatcagg
     6721 aagcagttcc ataaggacct gccggtagtg aaagcctttg gtctgcctgc catccgtgac
     6781 ctggcccaat acctggagca gaccggcgaa gaactgcaac cgtcaacagc agatgcgccc
     6841 tacgtttcag tagatatcat gaaaaacagc cttcttttga taaacaagtt taccgatgaa
     6901 gcataaccag ccttatacgg gtttagagat cgccatcata gggatggcct gccggtttcc
     6961 cggagcttcc tgctggcagg aattctggta caacctgact aatggcgtgg agtccgtccg
     7021 tttttataca gatgaagacc tggcggctgc aggcgttgca ccgcaagaga tagcgcgacc
     7081 cgactttgta aaagcagatg cggtactgga acacaaaacg cggttcgacg cagcgttttt
     7141 cggctacagg cccgaggagg ccagcgtact gaatcccatg caccgcattt tccatgaatg
     7201 tgtatgggag gccttggaag atgcaggata cgatccggct accgttaagt cggggatagg
     7261 cctgtacgcc gggggtggaa atgatctcaa ctggcgggtg tattccatgc tgcagcaaaa
     7321 taaccgggag gtcgacagct ttactttgtc acagttgaat aacaaggatt acctgtctgc
     7381 tttattgtct tataagctca acctgcgggg gccggccttt accgttaata cggcctgctc
     7441 cacctcgctg gtagctatta acctggcgtg caaaagttta ctgatggggg aaacaggcat
     7501 ggcgctggca ggcggcgtat ccttgaatac gcggcaacgg aaaggctact tttaccagga
     7561 gggtatgatc gattccaggg acgggcattg ccgcgctttc gacgcgctgg ccagtggcgc
     7621 cgtcggcggc gaaggggcag gcgtggtggt attgaaacgc ttacaggatg ctgtcagaga
     7681 cagggaccat atttatgcag tgataaaggg tagcgccatc aacaacgacg gtaacagaaa
     7741 ggttggattc accgcaccca gtattgaagg gcaggccgac tgtatacggc gggccctggc
     7801 gatggcggat acggcgcctt ccggtatcag ttacgtagaa gcgcatggca ccggtacgcg
     7861 cctgggtgat ccgattgaag tagaagccct taatacagcg tttaaccggg accgtagcca
     7921 ttcctgtgcg ctggggtctg taaaaacgaa catcggtcac ctggacacag ccgcgggtgt
     7981 agcggggctt ataaaaacgg cgctaagcct gaagtttaaa atgctcccgc ccactctgca
     8041 ttttcaatca cccaatccgg agattgattt tgaaggcggt cctttttatg tgaacgccag
     8101 gctgcagccc tggccggcag ccgatgatac gccgaggagg gccggtgtca gttcgtttgg
     8161 tatcggtggc accaatgcgc acgcggtgct ggaagaagct ccggctacca caacggcggc
     8221 agagggcagg ccatggaaac tgttcaccgt ttccgcccgt acgcccgttt ccgtttgccg
     8281 gtacctggaa aagataaaag cctttctgca gcaggaacta cgtccggcgc tggcagatat
     8341 gtcttttacg ctgcagacag gccgccggca ttttccatac cggtatgcct ttgcgtacca
     8401 gcatctggaa gacctgctgc acaaactgga caatatacct gcggaagctg ccatccggca
     8461 gaccgcagcg aataaaccac tgacagtgtt catgtttccc ggtcagggat cgcagtataa
     8521 tggtatggca caaacgctgt atgaacagga accttttatc aaagatatac tggacagggg
     8581 cttcggcatc atccggcagc ttaccggcaa atcgcttcag gaagtatggt tcgcggcgtc
     8641 agggacggaa atcaacagaa cactgtacgc ccagccagcc atcttcctgc tggaatatgc
     8701 catggcaaaa caactcatgg catggggtgt ccagccggat tatatgatcg ggcacagcat
     8761 cggggaactg gtagctgcct gcgtcagcgg tgtattctca tttgaagacg cactgaaaat
     8821 agtcgtaaaa agggccgccc ttatggacgg actgccggcc ggcagcatga tcagcgtgtc
     8881 gctcagccgc caggaggcgg acgcattgct gaatgagcac gtttgcctgg ctgctgtaaa
     8941 tgcaccggaa caactggtgc tgtcagggcc gcctgatgca atgcagcagg ctacggcaca
     9001 actggagcgc tccggcacac cacatgtccg gttacatacc tcccatgcat tccactctgc
     9061 tatgctggac cctgtcctgg cggaatttcg cgccgccctg gacgggatta ccccgggtga
     9121 aataaaaatc ccctttgtat ccaacgtgac cggagaatgg ataactgccg cagaggcgac
     9181 ttcgccggag tactggtccc gccacatgcg cgagactgta caactggcta ccgggataca
     9241 aaccataatg gcaacgtcaa cggatatatg ttttatagaa gcgggagcag gtcatatctt
     9301 atccggtctg ctaaagcaac aactttccgg tgatacgcat atcgttgcaa taccgctggt
     9361 acctgccgcc agggagcacc tgccggacgg gcagatgctg ggcaacgcta tcgcgcaact
     9421 gtggatgaat ggcatcagca ttgactggca gtgctattac agggaagaaa caagaagaag
     9481 ggtgccgttg cccgtgtatg cttttgaaca aacaacctac ccggtagaag tagacccctt
     9541 caaactggga aacagatatc tgtctgcccc caaaaagaac gggtggcacc actggatata
     9601 ttatcctgta tggaaaagca gcatcctgct gcccgctacc ggaaaaataa aatccttcct
     9661 gttcctctcc ggcggaacag cctgggagac agcactggtc ggtcagctcc gcaccgcagg
     9721 gcacgaggtg atacaggtgg tggcggatac cgcgttccgg caggtggacg ggaaaatgta
     9781 cttcatggac ccggctgata aaggacagtt cgggctattg tctgcagcgc tgcggcagga
     9841 gggcgtgcac ttcaccgata tcctgtatgg atgggccgcc ggagcgatgg acgaggcgct
     9901 ggtactggaa gcgcaaaaca ggacgatcca tcagtgttac tttgcgttag cccacctgat
     9961 acaggcgttg caggacggcg ggcaactgaa caatacccat gttttcctgc tcacggacca
    10021 tctgttcaac attcatcata cagagaacag ccgttattcc caggcgctgg ctgtaggcct
    10081 gctgaatgcg ctgcaccagg aattacctgt gtcatccagt cacatcgaca tcgacagccg
    10141 tgcaacgctg tccggactgg tgcttgaact cgggcaggaa tcacatcagg aaagaacagt
    10201 cgcctggcgc ggacatagca gatgggtgag cgtttatcag cagaatgaaa cgcccctgcc
    10261 gcagcggcag cctgtgaaga aaaacggtgt ttatctcgtt accggcggtc tcggtaaggt
    10321 ggggttcctg ctggcacggc acctggtcgg cacctgtcag gccaaagtcg tattgacagg
    10381 acggcggaat gtggaacata ccgatgaaaa cgacgaatgg aacattcggt tgaaacagct
    10441 gcaggcaatg ggaacagcgg tatactaccg ttgtgatgcg gccgattacg atgcattaga
    10501 aacgacggtc agtcatgtca aagctaccct tggtcccgtt ctgggcgtga tacatgcggc
    10561 aggcaatatc gacaggcgat attttgaact gacggaggac atgtctgttg aaaatacgct
    10621 ggctgtttta cggcctaaag tggatggcat ccgaaacctc acccgggtat ttgaaaagga
    10681 atccccagat tttgtctgga tcacctccag cctggccagt gtactgggcg gcattggctt
    10741 tggtgcttat gcggcagcga acctgtttat ggaccactat atcagttccc gtttacagca
    10801 gcatccttcc tggaaatgta tcggtctttc tgaaatggcg cttgacgcat ctgaggaagc
    10861 agcggaagca cgccaggaac gaaaggcgct gctccccgct gaactcatag cattgtttga
    10921 gtggagcgcc ggcactcccg gtattccggt gatatggcaa acggcgcagg gcctcgggga
    10981 acgtttgcac aacacttacc acgccccgcg cgaaactgca gcgatactac caggcgcagc
    11041 agcggcggcc gccatacaac aaagaccggc gctgagcact gtctttgtgc cggccgctac
    11101 ttccacggaa caaatactct cccagatcat ggaacagtat ttcggattta ccggcattgg
    11161 cgtggatgat gatttttttg aactgggagg cgactcgtta aaggccatga tcttactgaa
    11221 aagaatccga caggcgctgg acgtacaaat cacagtgcat gatttctttg aagcacggac
    11281 catccggcag ctggctaccg gtatagacaa caggttatgg ctgcaggccg gtgaaaatcc
    11341 ggaaaacgca tttatttcta ttatatgatg gttaaacact gtaacggatg cacgaactac
    11401 ttaaaaagct gagagaacaa catattcaga tcgttttaga agatgataac ctgcggatca
    11461 gcagcgcggc gccgatacca acggcaatcg ctaatgcgat cagggagcat aaggcagcgc
    11521 tggtgcaata cctgaaaaac ggtttgcagg aaacgcctgc cgcagctaca atcccggtgg
    11581 cgccggaatc cagggggtat gcgctttcct ccgtgcagcg gcgtatgtgg gtgctcagtc
    11641 aataccagga aggcaatctg gcctataata tgccggccgc ctatctgctc gagggcgaac
    11701 ccgatgtcgc gaggctggaa cgcgcgttcg acctgctgat tgcacggcac gaaatactac
    11761 ggaccgcctt ccgggtcgat gaccagggag atatacggca atatattgaa tcatctcccc
    11821 agaagtttcg tatagcccca gaagacctac gcggtgcgga agaacagcgg gcgcagatag
    11881 atgaacggat acggcaggcg cacatcatcc cttttgacct ttcgtcgggg cccttgttac
    11941 gtgcgggtct gtatcgttta tctgaaaaga gctggctgtt cgtgtatgtg atgcatcata
    12001 ttaccggtga cggctggtcc atgggagtat tgatccgtga gctgatgcag ctttacaaca
    12061 ctgctgaaac aaacgacggc ctgtccctgc ttccgctgag gatacattac aaagattatg
    12121 cagcgtggca acaggcccgg ctggcggatg ccggcatgga gccctgccgg aaatactggc
    12181 tggaacagtt agcgggggaa ataccggtgt tgcagttgcc ggcggacaac gcccggccgg
    12241 ccattaaaac ctatcatggc gcggcgatac agcaacgact cgatccggaa gtatttgcca
    12301 ggttcagggc gctggtgcag gaacagggag ctaccttatt tatgggtctg caggcggctg
    12361 tcaatatact gttgtactgg tactccggcc aggaggatat tatcaccggt actcccattg
    12421 ccggcagaga ccatcctgaa ctggaagacc agatcggcgt gtatatcaat accctggcgc
    12481 tgcgggtacg ttgccaggcg gaagacacct atctgcagct gctcagtaag gtcagacagg
    12541 tgacactgaa cgcctatcgt tatcagtcat atccgtttga tgagttggtg gatgaattgc
    12601 agctccggcg tgatatgagc cgcaatccac tgttcgatgt gatggtgagc cttcagaata
    12661 acgatatcaa cctggccggc gaccatcgga tgggatcact tgccgtcagc cggtaccccg
    12721 acgggcaaaa tatcttctgc aaattcgacc tgacgttcga cttcatcgag acagccggta
    12781 cgctgcaaat gacgattgaa tacaataccg acctttatcg ttcttccacc atagacctga
    12841 tgatggggca cctgcggcaa ctgatcaccg gtattacggc ttcaccttcc acggttatac
    12901 gggaattgga cctgctcacg gagaaagaac ggcagcagct gttgtctgat tttaataaca
    12961 cggaagggga ttatgagcgg gacaagacca ttgtggcgct gttccgccgg caggcattgc
    13021 tgcggccgga agagacggcc gttgtttttg aagacagcgc gttgacttac cgggagctgg
    13081 atgaacggtc cgaccgggtg gcgcggctgc tgacggaaca actgcaggta caaccaggag
    13141 cgttggtagc gctgctgacg gaacgctctg ttcacctgat ggcggggatg ttaggcatcc
    13201 tcaaagccgg agcggcttat gtgccgctgg acccggccta tcctgcggag cgtatcagct
    13261 acgtgctgga ggactgcggc gcccgcgtgc tggtggccgg cgaaggaaca gcgctgccgg
    13321 caggctatga cggcgccgta ct
//
