LOCUS       NZ_FUWZ01000015        17642 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000015
VERSION     NZ_FUWZ01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 17642
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..17642
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     gene            <1..678
                     /locus_tag="B5D63_RS34310"
                     /old_locus_tag="SAMN04488128_1151"
     CDS             <1..678
                     /NRPS_PKS="Domain: PCP (133-200). E-value: 3.8e-23. Score:
                     73.5. Matches aSDomain: nrpspksdomains_B5D63_RS34310_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024591.5"
                     /locus_tag="B5D63_RS34310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1151"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_235021704.1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-21, bitscore:
                     65.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.3e-15, bitscore:
                     44.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GDLARWLPDGRLECLGRLDDQVKVRGHRIEPGEIEAALQQYPGVE
                     RALVMVRKDPAGDHVLVAYLVTAAPISPPSLQAHLSRTLPAYMLPGHYVKLTSFPLTPN
                     GKTDRKQLPEPWAQGLKPATVYVAPRNELEQAFSDIWQTVLAKERIGIHDDFFEQGGQS
                     LKAIRLVAQINKRWSLGMGIIDVFSHPTVAEMADWAGTTLWLKEADKEPVMQDQEENEK
                     IIF"
     source          1..17642
                     /db_xref="taxon:634771"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070509_115"
                     /organism="Chitinophaga eiseniae"
                     /strain="DSM 22224"
                     /type_material="type strain of Chitinophaga eiseniae"
     cand_cluster    1..17642
                     /SMILES="NC(C(C)C)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..17642
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[8748:>17642](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8749..>17642
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..17642
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:678](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      <1..678
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     CDS_motif       43..108
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34310_0001"
                     /evalue="2.40E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="B5D63_RS34310"
                     /protein_end="35"
                     /protein_start="13"
                     /score="41.8"
                     /tool="antismash"
                     /translation="CLGRLDDQVKVRGHRIEPGEIE"
     aSDomain        403..603
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34310_PCP.1"
                     /evalue="3.80E-23"
                     /label="B5D63_RS34310_PCP.1"
                     /locus_tag="B5D63_RS34310"
                     /protein_end="200"
                     /protein_start="133"
                     /score="73.5"
                     /tool="antismash"
                     /translation="EQAFSDIWQTVLAKERIGIHDDFFEQGGQSLKAIRLVAQINKRWS
                     LGMGIIDVFSHPTVAEMADWAG"
     gene            700..2349
                     /locus_tag="B5D63_RS34315"
                     /old_locus_tag="SAMN04488128_1152"
     CDS             700..2349
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (72-373). E-value:
                     4.3e-97. Score: 316.7. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34315_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="B5D63_RS34315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1152"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_078673416.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-81, bitscore:
                     263.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTAIKNILDTLRARNVRISLNGERLQVEAARGIIDEQLRQLIK
                     DNKEALIAYIRQVVRQEDITIQPAPMATSYPLSSSQRRLWILSQLEAGDTAYHIAVGYR
                     FEGTLVVQALEKAFQRLIERHEILRTVFRVQEDGEPVQVVLPAAHSGFSLLQDDLRDRH
                     DKDEEIRKRLNETLMVPFLLTTPPLLRAGLYRTDDDQWTLLAVIHHIISDAWSMNILMQ
                     ELMQFYFAESNSVPAATPLKIQYKDYASWQQQQLLHGGFDEHRAYWLSQFEQGVPVLRL
                     RGDRPRPETKTYHGGTVRKEISHRLIQPLKTLTQESGTTLFAGLLAIVQVLLSRYTGQR
                     ETVLGTLVAGRTHVDLEDQIGFYVNTIALRLPLDAENGFRQLLAGMKQTLSGAYKYQDY
                     PFDELVKTLGAARDASRHPLFDVLVVLQDATPLAEKKAGVTDQLNVTLYDLPLAPNTSK
                     FDLSFDFVETATGLMLTIEYNSDIYLPASIYRMGDHLEKLLEVLLQSPDHAVGKADYLT
                     ENEKQALIAQAGHAAADYFMAKQQIQLAETAG"
     aSDomain        916..1818
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34315_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.30E-97"
                     /label="B5D63_RS34315_Condensation_LCL.1"
                     /locus_tag="B5D63_RS34315"
                     /protein_end="373"
                     /protein_start="72"
                     /score="316.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDA"
                     /tool="antismash"
                     /translation="TSYPLSSSQRRLWILSQLEAGDTAYHIAVGYRFEGTLVVQALEKA
                     FQRLIERHEILRTVFRVQEDGEPVQVVLPAAHSGFSLLQDDLRDRHDKDEEIRKRLNET
                     LMVPFLLTTPPLLRAGLYRTDDDQWTLLAVIHHIISDAWSMNILMQELMQFYFAESNSV
                     PAATPLKIQYKDYASWQQQQLLHGGFDEHRAYWLSQFEQGVPVLRLRGDRPRPETKTYH
                     GGTVRKEISHRLIQPLKTLTQESGTTLFAGLLAIVQVLLSRYTGQRETVLGTLVAGRTH
                     VDLEDQIGFYVNTIALRLPL"
     CDS_motif       982..1098
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34315_0001"
                     /evalue="6.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="B5D63_RS34315"
                     /protein_end="133"
                     /protein_start="94"
                     /score="57.2"
                     /tool="antismash"
                     /translation="TAYHIAVGYRFEGTLVVQALEKAFQRLIERHEILRTVFR"
     CDS_motif       1318..1383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34315_0002"
                     /evalue="2.30E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="B5D63_RS34315"
                     /protein_end="228"
                     /protein_start="206"
                     /score="39.3"
                     /tool="antismash"
                     /translation="IHHIISDAWSMNILMQELMQFY"
     CDS_motif       1429..1467
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34315_0003"
                     /evalue="2.10E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34315"
                     /protein_end="256"
                     /protein_start="243"
                     /score="13.9"
                     /tool="antismash"
                     /translation="QYKDYASWQQQQL"
     CDS_motif       1726..1809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34315_0004"
                     /evalue="8.30E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34315"
                     /protein_end="370"
                     /protein_start="342"
                     /score="37.5"
                     /tool="antismash"
                     /translation="VLGTLVAGRTHVDLEDQIGFYVNTIALR"
     CDS_motif       1858..1977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34315_0005"
                     /evalue="1.30E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34315"
                     /protein_end="426"
                     /protein_start="386"
                     /score="56.2"
                     /tool="antismash"
                     /translation="KQTLSGAYKYQDYPFDELVKTLGAARDASRHPLFDVLVVL"
     misc_feature    2355..2368
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.82"
                     /tool="antismash"
     misc_feature    complement(2378..2387)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            2392..2988
                     /locus_tag="B5D63_RS34320"
                     /old_locus_tag="SAMN04488128_1153"
     CDS             2392..2988
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS34320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_1153"
                     /product="hypothetical protein"
                     /protein_id="WP_078673417.1"
                     /transl_table=11
                     /translation="MKFPLYLLCLTFLSLFTACAQQQPAAPYKFDIPSGWTTETFPIPI
                     DFAPTIPYKGKEELRFTPGWGAPGEEHWSYAFVWWLEGMPEISEATLQRDLEAYYGGLV
                     GRNITKRNIPADKVVPTKVAIRKVATASGYAATYSGTVDMLDYMALEPITLNCVIHLFR
                     CKKDNHTGIYFEVSPKKSNDPLWQQFEKLLSVQCK"
     gene            complement(3002..4012)
                     /locus_tag="B5D63_RS34325"
                     /old_locus_tag="SAMN04488128_1154"
     CDS             complement(3002..4012)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012888.5"
                     /locus_tag="B5D63_RS34325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1154"
                     /product="sulfotransferase"
                     /protein_id="WP_078673418.1"
                     /transl_table=11
                     /translation="MTLQQSLKKKRYLLHKIYEHYRFVKPYMARNKKGGHTNTVTNISI
                     FSEPRGGSTWMASLLTRLPQSVLVFEPMFLIPAYREIKPVQFVFNQYIPEEAAWPEATE
                     YFRKLYHQEIDSFSSLRLYYSNKSLRDIRNSRYFIYKDVNSNMLLPWLTRQFDINPIYL
                     LRHPCAVISSQLKYRHWDYIQQDLRAYFPDPKDRHQELFEQYKDVIGKISKPEERLAAE
                     WALHNVVPLKHPENNRRWITVSYEKLYNEPETELENIFSRLGVDMPAEIYSAIRKPSFT
                     TINSSKSLIEQGGQLAAWKQSLTTAQVRNILQIVREFGIDIYDESPEPDYSRIYV"
     gene            4098..4997
                     /locus_tag="B5D63_RS34330"
                     /old_locus_tag="SAMN04488128_1155"
     CDS             4098..4997
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042586.3"
                     /locus_tag="B5D63_RS34330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1155"
                     /product="DUF6734 family protein"
                     /protein_id="WP_078673419.1"
                     /transl_table=11
                     /translation="MKIVQSFWTKPFLRSPDLLKDTRLNGGWPSRKYNYFSWALSCLQL
                     RSFYDEVELVTDDLGKLMLIDKIGLPYTNVRVVMDKLDNYNPGLWALGKVYTYSIQDRP
                     FLHVDNDVFIWQPFEDRVMSAPLAAQNLEGAASSYAATFNDICDKFPYIRPGIRELYGK
                     KIIECSNAGILGGSDIAFFQEYTAEVFHFLKQNEEHLDHHMMHMNSTYINVVYEQVFFY
                     WMAQAQQREVTYLFPDVIDFPNYIGYFHEALPNKNFVHCLGVFKQIRHVCNMLSRELKH
                     RYPEYYYRIQELVASSEI"
     gene            5011..6567
                     /locus_tag="B5D63_RS34335"
                     /old_locus_tag="SAMN04488128_1156"
     CDS             5011..6567
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="B5D63_RS34335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1156"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_078673420.1"
                     /sec_met_domain="LANC_like (E-value: 5.3e-19, bitscore:
                     57.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEILNTAAGVSPAAYRICQSIDRMEAPLTGADIKKVVPAKCAFML
                     ELFRRTGEQAVWNDLITLAAQLKTYQESPGYNYTLYGGRMGIAWFYLGLYRTSGESQWL
                     QEARQIAMDYLQGESFRYSIIATSGVATGLAGILLVLLHVYKETQDPEILEGLEKIVLQ
                     LAFRAKQGRKGIHWGNATNCEGANTGFKNGAAGIALVLSEVSRYFSSGILEALAAKALE
                     YEADYQADPVSAGCPGSEAPYGEGFFLLKYMQIMETENGDGGLPEGLPLRSVFGPEGYD
                     ILDAYLQSAFRRTCSLLKSLRPNVLQAYYSEYGIPDIAAFEKYIEGWLAAVEEHTDVTA
                     VRVEFEREQFILSVRRSLGFRCRPVADDEAGVEQLEAQMPLSTERFLSLRLVHAPSVRT
                     RSWEETMDLSRVLTVPEFASFFQHYGARFCICYLSLDDTLQDINPGIIRLVFEQFDQPV
                     TIREAAQRIVTFIQQQPAPALALLKDHYYVTDDEQLFGKIVNLVIDGARLHMAEGILVA
                     T"
     misc_feature    6611..6627
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.77"
                     /tool="antismash"
     misc_feature    complement(6719..6739)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.37"
                     /tool="antismash"
     gene            6817..8445
                     /locus_tag="B5D63_RS34340"
                     /old_locus_tag="SAMN04488128_1157"
     CDS             6817..8445
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014218587.1"
                     /locus_tag="B5D63_RS34340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1157"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_235021705.1"
                     /transl_table=11
                     /translation="MEDLYYLKPNLVIEPLFKRWYAWSYLIPPATAARNVTGRHMKIIN
                     SYIQAPQIHMEAVRNPKMKGGPFMDFGRNRVEEVRALREDTLSSQQDLVALSDALKELD
                     QLLKEHAKGYSLEPLYAKVPDILKGYVELNYDLNNQPSFRIVESLLYKSKYYQEQFQSI
                     ALWVTENDERPFVLSTPRLDEPNVLHLPVAFNDRLIDEIARMKHTPNTISYLKELLNVS
                     KEDEALLETFFTKDAPPPYQRYEGDKIRMRYFGHACILIETKEVSILVDPLISYYGYNT
                     ELARFSDMHLPPVIDYVLITHNHQDHILFETLLPLRHRIRNIVVPRGGYGQLQDPNLKM
                     VLQQTGFKNVLELEEMGTLEMGDCTITGIPFFGEHSDLSISTKICHYLQINDFKIMFAA
                     DSCVVEPRLYEHVQKEIGNLDVLFLGMECDGAPLSWLYGPLLTRDLPRDMDASRRLAGS
                     NFERGSAIVDIFQPAELYVYAMGQEPWLEFISSIKYTDESNPIVASNKLISECKEKGLA
                     AERLFGEKEILYNKHKSPATAHPVL"
     gene            8494..8712
                     /locus_tag="B5D63_RS34345"
                     /old_locus_tag="SAMN04488128_1158"
     CDS             8494..8712
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS34345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_1158"
                     /product="hypothetical protein"
                     /protein_id="WP_143313363.1"
                     /transl_table=11
                     /translation="MAKQKMESLMDRVRAHFAYMKEFFSEYNAQLGEDMPRQLPSFTDE
                     EMMIYCGHPEAQASGPAASPEEPPAAK"
     gene            8749..15720
                     /locus_tag="B5D63_RS34350"
                     /old_locus_tag="SAMN04488128_1159"
     CDS             8749..15720
                     /NRPS_PKS="Domain: PCP (110-179). E-value: 7.4e-25. Score:
                     78.9. Matches aSDomain: nrpspksdomains_B5D63_RS34350_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (193-495). E-value:
                     5.6e-98. Score: 319.6. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34350_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (666-1063). E-value:
                     8.8e-104. Score: 339.2. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34350_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1172-1239). E-value: 1.1e-25.
                     Score: 81.6. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34350_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1256-1555). E-value:
                     5.6e-98. Score: 319.6. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34350_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1729-2126). E-value:
                     3.6e-101. Score: 330.6. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34350_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2234-2301). E-value: 7.5e-26.
                     Score: 82.1. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34350_PCP.3"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="B5D63_RS34350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1159"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_078673423.1"
                     /sec_met_domain="Condensation (E-value: 5.8e-76, bitscore:
                     244.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-111, bitscore:
                     361.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-20, bitscore:
                     62.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVSIENTAHNLRIYILDEHDLLVPVGVAGKICVGYDHLSAIEKY
                     FPGGPAHSPTPDPFRKGAWLCRTGDTGRWLDTGRLELLTDNHITDTVSALPDPAATTFE
                     TPRSTFEQQLLDIWRSVLGKQEISIHDDFFRSGGHSLKAVQLFARVRQLMGLSLQMKDV
                     FTHTTIAAQAAFLEKAATSRESGIVRAPHQSSYPLSHAQRRFWMLSQFEERSRAYHIAN
                     VCTLKGQLDKKALQRALSFVLNRHESLRTVFRLNEAGDVRQYVLPVWEVACAPRYEDIT
                     GSPDTGAALRAIGDHEQLAVFDLSTAPLFRLTVVKTGDDEHVLFYTMHHIISDGWSMLV
                     LLRDVTAAYNALRVSALPELPRLDIQYKDYAHWQEQYLQGDTLAALEHYWMNQLSGELP
                     VTELPLDYPRPLVQSFSGHSMIREMPAVPAAALRKLCHMENTTLFTGLLSALSALLFRY
                     TGQEDMIIGTPVGGREQLALEDQIGVYLNTLPLRMQPQGDASFSSLLTKAKEALLGAYE
                     HQAYPFNMLTDKLAPPVNIGRSPLFDVMVVMQNQENITLDNTPDHLEGITTGGTQEFAL
                     QTSQVDLTFTFTERDGKLFLQITYNTALFKEATINRLFTHFFNLLREVTACPGQHICFL
                     KYLSDEEEQQQLYTFNHTAVAYPSTLTIADLFEAQADSTPDAVALVYEDQRMTYRELDD
                     AANRLAHHLMDSYHVKPDMLIGVMMDKSALMMIGILGILKAGAAYVPVDRSYPAARAGA
                     LLQDASVQLLITDSAAVFDLIEYYQGDIMALDLQLDSLPAREGRPARQAGPAHLAYVMY
                     TSGSTGRPKGVMVTHQSVVRLVKNTGIVAFSGQDVLLSTGAVSFDAVTFEYWGMLLNGG
                     RLVLTGRETLLDYTLLGRLVRKEAVTMMWFTASWFNQLVDADASLFATLAVVLAGGDRL
                     SPHHIGKLRTLYPSLVVINGYGPTENTTFSATWQVTDEDVEDIPIGLPVSNSTCYILDA
                     NRQLLPLGLAGELYVGGDGLARGYLQAPELTETQFIPHPFVPGERLYRTGDMCRYRPDG
                     VITFLGRKDQQVKIRGHRVEPAEVAAAISRVTGVTQAVVTVIDLPGNDKGLAAYFTALP
                     GTDVDMVSAALTTLLPEYMQPQAMMLLDQFPLNANGKVAAGELPPPDMTALRGTTAAYL
                     APRNETEERLSHIWEEVLERKNIGVNDHFFDLGGHSLKAIQLISRIRKEWSADVQIKDI
                     FSHPRLAEMAALIAVAGQQAVEEIPALPPSECYVLSNAQLRFWVLSRFTDSSLAYNMAM
                     GLRLNGPLEEALLKAALHTVVSRHESLRTVFRQTPSGEVMQFVQPAEEITLNWSYRDIS
                     GEPQPEQALKTIYAEEQLRPFDLGQGPLLRTILVKTGPNNHAFFYTMHHIISDGWSMQV
                     LAKEVVSIYNALLHGRLPDLPPLRIQYRDYAAWQQSRLDQLQQQEDYWMRQLEGDLPVL
                     DLFPGKTRPPIQTHHGDSLSVTLLQGNMEELYRYCNREAVTPFMLLLAAIKGLFYRYSG
                     QEDIIVGIPVAGREQQELENQIGIYLNTLPLRTRFNAAQSFRDLLLKEKEVLLEAYGNQ
                     ECPFDRLLELRKVNRDISRSALFDVLVVLQNQSNTNIYSGDDGMEGLTASYIDGLKAET
                     SQFDLTFSFAETSEGIQLSLSYNTDVFEREEIVRLSGHYAQFLSAVVKDAGVPLSRVDY
                     ISEGEKQLLLQTFNDNSVVVHETITVPDILAMHMQGQPDAPAVTDERGTVTYRMLERMA
                     GNMAYRLQTAYGVEKGDLVMILADRSSLFVAAILAIWKCGAAYVPVDPDYPASRIQAII
                     NASSPAAVICDEKYQVLAGGFAALINLLTADGEENIPKPVHIMPADLAYVIFTSGSTGE
                     PKGVMIEHQGMLNHLYAKTESMEMSAASVVAQNASQSFDISVWQFFAALITGGRTVIYS
                     DQEIFEPLACWEKIRREGVTILEVVPSYLSLLLDLLAQQEERPVLSLKYLVVTGETLKA
                     VLVRKWFEFYPHVPMVNAYGPTEASDDITHHFMTEAPLTDNIPIGKPVRNMNIYVLDAH
                     RQLCPVGVAGEIYVAGIGVGRGYLNDPDKTAGAFMDNPFSKAASERMYKTGDVGRFLPD
                     GNIEFYGRKDYQVKIRGNRIEPGEIESVLLRQESVKAAEVLPMEGADGRTMLVAYVVAV
                     GDEVATRLRDHLAGLLPDYMVPAHIIAIAQMPLTPNGKTDRRALEKMLPLEVHSHKTGE
                     PPADDMEATLVNIWEEVLGVEEIGVNDSFFELGGHSLGVIRILNAVQQQFDVKVDMREL
                     FKRPTVRQLAQEIKLLHALREPSVTTNNHHSKEIII"
     aSDomain        9079..9285
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34350_PCP.1"
                     /evalue="7.40E-25"
                     /label="B5D63_RS34350_PCP.1"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="179"
                     /protein_start="110"
                     /score="78.9"
                     /tool="antismash"
                     /translation="EQQLLDIWRSVLGKQEISIHDDFFRSGGHSLKAVQLFARVRQLMG
                     LSLQMKDVFTHTTIAAQAAFLEKA"
     aSDomain        9328..10233
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34350_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.60E-98"
                     /label="B5D63_RS34350_Condensation_LCL.1"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="495"
                     /protein_start="193"
                     /score="319.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="SSYPLSHAQRRFWMLSQFEERSRAYHIANVCTLKGQLDKKALQRA
                     LSFVLNRHESLRTVFRLNEAGDVRQYVLPVWEVACAPRYEDITGSPDTGAALRAIGDHE
                     QLAVFDLSTAPLFRLTVVKTGDDEHVLFYTMHHIISDGWSMLVLLRDVTAAYNALRVSA
                     LPELPRLDIQYKDYAHWQEQYLQGDTLAALEHYWMNQLSGELPVTELPLDYPRPLVQSF
                     SGHSMIREMPAVPAAALRKLCHMENTTLFTGLLSALSALLFRYTGQEDMIIGTPVGGRE
                     QLALEDQIGVYLNTLPLRMQP"
     aSModule        9328..12465
                     /complete
                     /domains="nrpspksdomains_B5D63_RS34350_Condensation_LCL.1"
                     /domains="nrpspksdomains_B5D63_RS34350_AMP-binding.1"
                     /domains="nrpspksdomains_B5D63_RS34350_PCP.2"
                     /locus_tags="B5D63_RS34350"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9397..9510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0001"
                     /evalue="4.50E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="254"
                     /protein_start="216"
                     /score="44.8"
                     /tool="antismash"
                     /translation="AYHIANVCTLKGQLDKKALQRALSFVLNRHESLRTVFR"
     CDS_motif       9730..9795
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0002"
                     /evalue="3.10E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="349"
                     /protein_start="327"
                     /score="35.6"
                     /tool="antismash"
                     /translation="MHHIISDGWSMLVLLRDVTAAY"
     CDS_motif       9844..9882
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0003"
                     /evalue="5.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="378"
                     /protein_start="365"
                     /score="12.7"
                     /tool="antismash"
                     /translation="QYKDYAHWQEQYL"
     CDS_motif       10135..10224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0004"
                     /evalue="3.20E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="492"
                     /protein_start="462"
                     /score="29.2"
                     /tool="antismash"
                     /translation="DMIIGTPVGGREQLALEDQIGVYLNTLPLR"
     CDS_motif       10273..10392
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0005"
                     /evalue="4.00E-13"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="548"
                     /protein_start="508"
                     /score="41.7"
                     /tool="antismash"
                     /translation="KEALLGAYEHQAYPFNMLTDKLAPPVNIGRSPLFDVMVVM"
     aSDomain        10747..11937
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34350_AMP-binding.1"
                     /evalue="8.80E-104"
                     /label="B5D63_RS34350_AMP-binding.1"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1063"
                     /protein_start="666"
                     /score="339.2"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEAQADSTPDAVALVYEDQRMTYRELDDAANRLAHHLMDSYHVKP
                     DMLIGVMMDKSALMMIGILGILKAGAAYVPVDRSYPAARAGALLQDASVQLLITDSAAV
                     FDLIEYYQGDIMALDLQLDSLPAREGRPARQAGPAHLAYVMYTSGSTGRPKGVMVTHQS
                     VVRLVKNTGIVAFSGQDVLLSTGAVSFDAVTFEYWGMLLNGGRLVLTGRETLLDYTLLG
                     RLVRKEAVTMMWFTASWFNQLVDADASLFATLAVVLAGGDRLSPHHIGKLRTLYPSLVV
                     INGYGPTENTTFSATWQVTDEDVEDIPIGLPVSNSTCYILDANRQLLPLGLAGELYVGG
                     DGLARGYLQAPELTETQFIPHPFVPGERLYRTGDMCRYRPDGVITFLGRKDQQVKIR"
     CDS_motif       10936..10977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0006"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="743"
                     /protein_start="729"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGILKAGAAYVPVD"
     CDS_motif       11170..11229
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0007"
                     /evalue="6.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="827"
                     /protein_start="807"
                     /score="34.0"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGRPKGVMVTH"
     CDS_motif       11731..11820
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0008"
                     /evalue="1.60E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1024"
                     /protein_start="994"
                     /score="42.8"
                     /tool="antismash"
                     /translation="PLGLAGELYVGGDGLARGYLQAPELTETQF"
     CDS_motif       11902..11964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0009"
                     /evalue="7.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1072"
                     /protein_start="1051"
                     /score="34.1"
                     /tool="antismash"
                     /translation="FLGRKDQQVKIRGHRVEPAEV"
     aSDomain        12265..12465
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34350_PCP.2"
                     /evalue="1.10E-25"
                     /label="B5D63_RS34350_PCP.2"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1239"
                     /protein_start="1172"
                     /score="81.6"
                     /tool="antismash"
                     /translation="EERLSHIWEEVLERKNIGVNDHFFDLGGHSLKAIQLISRIRKEWS
                     ADVQIKDIFSHPRLAEMAALIA"
     aSDomain        12517..13413
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34350_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.60E-98"
                     /label="B5D63_RS34350_Condensation_LCL.2"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1555"
                     /protein_start="1256"
                     /score="319.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="CYVLSNAQLRFWVLSRFTDSSLAYNMAMGLRLNGPLEEALLKAAL
                     HTVVSRHESLRTVFRQTPSGEVMQFVQPAEEITLNWSYRDISGEPQPEQALKTIYAEEQ
                     LRPFDLGQGPLLRTILVKTGPNNHAFFYTMHHIISDGWSMQVLAKEVVSIYNALLHGRL
                     PDLPPLRIQYRDYAAWQQSRLDQLQQQEDYWMRQLEGDLPVLDLFPGKTRPPIQTHHGD
                     SLSVTLLQGNMEELYRYCNREAVTPFMLLLAAIKGLFYRYSGQEDIIVGIPVAGREQQE
                     LENQIGIYLNTLPLRTRF"
     aSModule        12517..15651
                     /complete
                     /domains="nrpspksdomains_B5D63_RS34350_Condensation_LCL.2"
                     /domains="nrpspksdomains_B5D63_RS34350_AMP-binding.2"
                     /domains="nrpspksdomains_B5D63_RS34350_PCP.3"
                     /locus_tags="B5D63_RS34350"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       12583..12696
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0010"
                     /evalue="1.80E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1316"
                     /protein_start="1278"
                     /score="52.5"
                     /tool="antismash"
                     /translation="AYNMAMGLRLNGPLEEALLKAALHTVVSRHESLRTVFR"
     CDS_motif       12916..12981
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0011"
                     /evalue="6.90E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1411"
                     /protein_start="1389"
                     /score="34.6"
                     /tool="antismash"
                     /translation="MHHIISDGWSMQVLAKEVVSIY"
     CDS_motif       13030..13068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0012"
                     /evalue="4.40E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1440"
                     /protein_start="1427"
                     /score="13.0"
                     /tool="antismash"
                     /translation="QYRDYAAWQQSRL"
     CDS_motif       13315..13404
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0013"
                     /evalue="1.70E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1552"
                     /protein_start="1522"
                     /score="39.7"
                     /tool="antismash"
                     /translation="DIIVGIPVAGREQQELENQIGIYLNTLPLR"
     CDS_motif       13453..13572
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0014"
                     /evalue="1.60E-09"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1608"
                     /protein_start="1568"
                     /score="30.0"
                     /tool="antismash"
                     /translation="KEVLLEAYGNQECPFDRLLELRKVNRDISRSALFDVLVVL"
     aSDomain        13936..15126
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34350_AMP-binding.2"
                     /evalue="3.60E-101"
                     /label="B5D63_RS34350_AMP-binding.2"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="2126"
                     /protein_start="1729"
                     /score="330.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HMQGQPDAPAVTDERGTVTYRMLERMAGNMAYRLQTAYGVEKGDL
                     VMILADRSSLFVAAILAIWKCGAAYVPVDPDYPASRIQAIINASSPAAVICDEKYQVLA
                     GGFAALINLLTADGEENIPKPVHIMPADLAYVIFTSGSTGEPKGVMIEHQGMLNHLYAK
                     TESMEMSAASVVAQNASQSFDISVWQFFAALITGGRTVIYSDQEIFEPLACWEKIRREG
                     VTILEVVPSYLSLLLDLLAQQEERPVLSLKYLVVTGETLKAVLVRKWFEFYPHVPMVNA
                     YGPTEASDDITHHFMTEAPLTDNIPIGKPVRNMNIYVLDAHRQLCPVGVAGEIYVAGIG
                     VGRGYLNDPDKTAGAFMDNPFSKAASERMYKTGDVGRFLPDGNIEFYGRKDYQVKIR"
     CDS_motif       14116..14157
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0015"
                     /evalue="2.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1803"
                     /protein_start="1789"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LAIWKCGAAYVPVD"
     CDS_motif       14335..14394
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0016"
                     /evalue="3.40E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="1882"
                     /protein_start="1862"
                     /score="34.8"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGEPKGVMIEH"
     CDS_motif       14914..15003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0017"
                     /evalue="2.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="2085"
                     /protein_start="2055"
                     /score="48.5"
                     /tool="antismash"
                     /translation="PVGVAGEIYVAGIGVGRGYLNDPDKTAGAF"
     CDS_motif       15091..15156
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34350_0018"
                     /evalue="2.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="2136"
                     /protein_start="2114"
                     /score="32.8"
                     /tool="antismash"
                     /translation="FYGRKDYQVKIRGNRIEPGEIE"
     aSDomain        15451..15651
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34350_PCP.3"
                     /evalue="7.50E-26"
                     /label="B5D63_RS34350_PCP.3"
                     /locus_tag="B5D63_RS34350"
                     /protein_end="2301"
                     /protein_start="2234"
                     /score="82.1"
                     /tool="antismash"
                     /translation="EATLVNIWEEVLGVEEIGVNDSFFELGGHSLGVIRILNAVQQQFD
                     VKVDMRELFKRPTVRQLAQEIK"
     gene            15720..>17642
                     /locus_tag="B5D63_RS34355"
                     /old_locus_tag="SAMN04488128_11510"
     CDS             15720..>17642
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (70-372). E-value:
                     1.4e-99. Score: 324.9. Matches aSDomain:
                     nrpspksdomains_B5D63_RS34355_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="B5D63_RS34355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_11510"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_143313365.1"
                     /sec_met_domain="Condensation (E-value: 2.1e-79, bitscore:
                     256.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6e-26, bitscore:
                     80.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METAKFILYLKRIGVSVSLSDGQLRLRAEQDIPELVLAEVRERKP
                     ALIALLSEKLDQAGRADVIIPAPEQESYPLSHAQQRFWILSQSEAGSRAYNIPGVLLFE
                     GELDIAVFSRALDFVISRHESLRTVFRQNESGDIRQYILPDDAFPLPLQIFDLSDETNH
                     EAALTAMFDEEQETVFDLESGPLLRTRIVRLGAARHAFFYTMHHIISDGWSLVVLTREI
                     IQAYNCYKQGHGPVLPSLPLQYKDYAQWQHSEQQQSYFLQQEEYWLQQFSGPLPVLELP
                     FAKRRPALRTFRGASLARPLSTPMLNQLKDLCVKEECTLFMGLLAGLNALFFKYTGQED
                     IILGTPVAGREHPGLEDQIGLYINSLALRTRFEASDSFLSLLRKEKTVLINAYRHQAYP
                     YDKLVARLTPPKDTGRQPLFDILVGMQNQASANIYDRKAIFDGLLVSVPEGMRTAGSHF
                     DVSFTFVEAAGGLELVVIYNTDIFNDRDISDLFDCYQELMLHAVGDPGQRLSSLSWIGA
                     AAQQQLEPFSGIHQLPQLPAAMMAPDLFEAQARATPEAVALVHGSRKVSYRELNEAANR
                     IAHYLREKQQVKPGQLVGLMGERSPELVSGLLGIWKAGAGYVPLDAGYPEERIVHMLTD
                     AGIRLV"
     aSDomain        15930..16835
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS34355_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.40E-99"
                     /label="B5D63_RS34355_Condensation_LCL.1"
                     /locus_tag="B5D63_RS34355"
                     /protein_end="372"
                     /protein_start="70"
                     /score="324.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="ESYPLSHAQQRFWILSQSEAGSRAYNIPGVLLFEGELDIAVFSRA
                     LDFVISRHESLRTVFRQNESGDIRQYILPDDAFPLPLQIFDLSDETNHEAALTAMFDEE
                     QETVFDLESGPLLRTRIVRLGAARHAFFYTMHHIISDGWSLVVLTREIIQAYNCYKQGH
                     GPVLPSLPLQYKDYAQWQHSEQQQSYFLQQEEYWLQQFSGPLPVLELPFAKRRPALRTF
                     RGASLARPLSTPMLNQLKDLCVKEECTLFMGLLAGLNALFFKYTGQEDIILGTPVAGRE
                     HPGLEDQIGLYINSLALRTRF"
     CDS_motif       15999..16112
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34355_0001"
                     /evalue="1.00E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="B5D63_RS34355"
                     /protein_end="131"
                     /protein_start="93"
                     /score="56.5"
                     /tool="antismash"
                     /translation="AYNIPGVLLFEGELDIAVFSRALDFVISRHESLRTVFR"
     CDS_motif       16332..16397
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34355_0002"
                     /evalue="5.40E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="B5D63_RS34355"
                     /protein_end="226"
                     /protein_start="204"
                     /score="34.9"
                     /tool="antismash"
                     /translation="MHHIISDGWSLVVLTREIIQAY"
     CDS_motif       16446..16478
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34355_0003"
                     /evalue="1.70E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B5D63_RS34355"
                     /protein_end="253"
                     /protein_start="242"
                     /score="14.2"
                     /tool="antismash"
                     /translation="QYKDYAQWQHS"
     CDS_motif       16737..16826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34355_0004"
                     /evalue="8.20E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="B5D63_RS34355"
                     /protein_end="369"
                     /protein_start="339"
                     /score="43.9"
                     /tool="antismash"
                     /translation="DIILGTPVAGREHPGLEDQIGLYINSLALR"
     CDS_motif       16881..16991
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34355_0005"
                     /evalue="1.50E-12"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B5D63_RS34355"
                     /protein_end="424"
                     /protein_start="387"
                     /score="39.9"
                     /tool="antismash"
                     /translation="VLINAYRHQAYPYDKLVARLTPPKDTGRQPLFDILVG"
     CDS_motif       17541..17582
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS34355_0006"
                     /evalue="7.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="B5D63_RS34355"
                     /protein_end="621"
                     /protein_start="607"
                     /score="19.0"
                     /tool="antismash"
                     /translation="LGIWKAGAGYVPLD"
ORIGIN
        1 ggcgacctgg cgcggtggct gcctgacggc cgcctggaat gcctgggccg cctggatgac
       61 caggtgaaag tacgcggcca ccgcatagag cccggggaaa ttgaagccgc cctgcaacag
      121 taccccggcg tggaaagagc gctggtgatg gtcaggaaag atcctgctgg cgatcacgta
      181 ttggtggcct acctggtaac ggcagcacca atatcgccgc cttctctgca ggcacatttg
      241 tcgcgcaccc tacctgccta catgctgccg ggccactatg tgaaactgac ctccttcccg
      301 ctcacgccta atggtaaaac tgacaggaag caattgccgg agccatgggc gcagggcctg
      361 aagccggcta ccgtttacgt ggctccccgg aatgagctgg agcaggcgtt tagtgacata
      421 tggcaaaccg tactggcaaa agaaaggatc ggtatccatg acgatttttt tgaacagggc
      481 ggacaaagcc tcaaagccat aaggctggtc gcacaaataa ataaacgctg gtcgctgggc
      541 atgggaatta ttgacgtatt cagccatcct actgtggcgg aaatggctga ctgggccggt
      601 acgacgctct ggttaaaaga ggcagataaa gaaccggtga tgcaggacca ggaagaaaat
      661 gaaaaaataa tcttttaaac acccctataa aaaaagacaa tggcaacaac agcgataaag
      721 aatatactgg ataccttgag agcgcggaac gtccgcatct cgctgaacgg agaacggctc
      781 caggtggaag cggcccgggg cattatcgac gaacagctca ggcagttgat taaagacaat
      841 aaagaggccc tgatagccta tatccggcag gttgtgcggc aggaagatat caccattcag
      901 cctgccccga tggcgacttc ctatccgcta tcttcctcac aacggaggct gtggatattg
      961 tcacaactgg aagccggcga taccgcctat catattgctg tcggatatcg ttttgaagga
     1021 acactggtag tgcaggccct cgaaaaagcc tttcagcggc tgattgaaag acatgaaata
     1081 ctgaggaccg tgttccgggt gcaggaagac ggcgagccgg tgcaggtggt gcttcctgca
     1141 gcgcatagcg gtttctcact gttgcaggat gatctgcgcg acaggcatga caaagatgag
     1201 gaaatccgga aacggctaaa cgaaacgctg atggtcccgt ttctgttgac aacacctcca
     1261 ttgcttcggg cggggctgta caggacagac gacgaccaat ggacattgct ggcggtcata
     1321 caccatatta tcagcgatgc atggtctatg aatatactaa tgcaggagct gatgcagttt
     1381 tattttgctg aaagcaacag cgtaccggcc gctacgccgt tgaagataca atacaaagac
     1441 tacgcgtcgt ggcaacagca gcaattgctg catggcggtt ttgatgagca cagggcatac
     1501 tggctttcac aatttgaaca aggggttcct gtactgcgct tacggggcga ccgcccgcgg
     1561 ccggagacaa aaacttatca tggcggaacg gtccggaaag aaatcagtca ccggttgata
     1621 cagcctctga agacgctgac acaggaaagt ggcaccacgc tttttgcagg cctgctcgcc
     1681 atagtacagg tgcttctttc ccggtatacc ggtcagcggg agacggtgtt gggtacgctg
     1741 gtggccggaa gaacgcatgt tgacctcgaa gatcaaatag gcttttatgt aaacacaatc
     1801 gcattgcgtt tgccactgga tgcggagaat ggtttccggc agctgttggc cggaatgaag
     1861 caaaccctgt caggtgcata caaataccag gattacccct tcgatgaatt ggtaaaaacg
     1921 ctcggagcag cccgcgacgc cagccgtcat cctctgtttg acgtattggt ggttttacag
     1981 gacgcaacgc cgctggcgga gaagaaagcg ggagtgacgg accagttgaa cgtaacctta
     2041 tacgacctgc cgttagcccc gaataccagt aagtttgacc tgtcgtttga ttttgtggaa
     2101 acagcgacag gtctcatgct caccatagaa tacaacagcg atatttacct gccggccagc
     2161 atttacagga tgggcgatca cctggaaaag ttgctggaag tcctgttaca gtcgcctgat
     2221 catgccgtgg gcaaagcgga ttatctgacg gagaatgaaa aacaggcgct gatagctcag
     2281 gccggacatg cggccgccga ttattttatg gcaaagcaac aaatacagct ggcagaaaca
     2341 gccggataaa aaactatatt tgttattatt caccggctaa aaaaatatca gatgaaattc
     2401 ccgttatatt tgttgtgttt aacctttttg tcgttattca ccgcctgcgc gcaacagcaa
     2461 ccggcagcgc cttataagtt cgacattccg tccggatgga ccaccgagac atttccgatt
     2521 cccatcgact ttgcgccgac gatcccttat aaaggaaaag aggagttgcg gttcactccg
     2581 gggtggggcg ctcccggcga agaacattgg tcctatgcat ttgtatggtg gctggaaggg
     2641 atgccggaaa tcagcgaagc cacattgcag cgtgacctgg aggcgtatta tggcggtttg
     2701 gtgggacgta atattaccaa gcggaatatt cctgccgata aagtggtgcc aacaaaagta
     2761 gctatccgga aagtggcaac tgcgtccgga tatgcagcca cctattcagg aactgtcgat
     2821 atgctggact acatggccct ggagcccatc acgctgaact gcgtgatcca tttgttcagg
     2881 tgtaagaaag ataatcatac cggaatctat tttgaagtgt cgccaaagaa atccaacgat
     2941 ccgttatggc agcagtttga aaaattactg agcgtgcagt gtaaataatg cgctcgcgga
     3001 tttaaacata aatccggcta taatcgggtt ccggtgattc atcataaatg tctataccga
     3061 attcacgaac gatttgcagg atgttgcgga cctgcgctgt ggtcagcgac tgcttccaag
     3121 cagccagctg gcctccctgc tcgataagtg atttggaact gttgatagta gtgaaactgg
     3181 gcttccggat agcggaatat atttcagcag gcatgtcaac ccccagtctg ctgaatatat
     3241 tctccagttc agtttcaggt tcgttatata atttctcgta ggataccgtt atccaccggc
     3301 ggttgttttc cgggtgtttt aacggaacaa cattgtgtaa ggcccattct gcagcaagcc
     3361 gttcctccgg cttcgatatt ttaccaataa catctttgta ttgttcgaac agctcctggt
     3421 gcctgtcttt aggatcaggg aaataggctc tcagatcttg ttgtatataa tcccagtgcc
     3481 ggtattttag ttgagaacta ataaccgcgc agggatgacg cagcaggtat atggggttga
     3541 tatcgaattg cctggtaagc cagggcaaca gcatgttact gttgacatcc ttgtagatga
     3601 agtaccggct gttacggatg tcgcgcaggc ttttgttgct gtaataaagt ctgagtgacg
     3661 agaatgagtc aatctcctgg tgatagagct ttctgaagta ctctgtggct tccggccatg
     3721 ctgcttcttc cggtatgtat tgattgaata caaactgcac gggtttaatc tcgcggtaag
     3781 cagggatgag aaacataggt tcgaagacca gtacgctttg tggcagcctg gtaagcaggg
     3841 aggccatcca ggtagaaccg cccctgggtt ctgaaaagat actgatgttg gtgactgtgt
     3901 tggtgtgtcc gccttttttg ttcctggcca tgtagggttt tacaaaccgg tagtgctcgt
     3961 agattttgtg caggaggtac cgtttctttt tgagtgattg ctggagggtc atgttggaaa
     4021 aggttgaaga gttaaaaaca gttattcgaa taagatttaa ttaaggtaat aaaaatgaaa
     4081 aaagaataca acaacttatg aaaattgtac aaagtttctg gaccaaacct tttctcaggt
     4141 ctcctgattt actcaaggat acaaggctca atggcggctg gccttcgagg aaatacaact
     4201 atttcagctg ggcgctttcc tgtttgcagc tacgtagttt ttatgacgaa gtcgaactgg
     4261 taacagatga tcttggtaag ctgatgctga tagacaagat cggacttccc tacacgaacg
     4321 tgcgtgttgt catggataag ctggataact ataaccccgg actatgggca ttggggaagg
     4381 tgtataccta tagtatacag gaccggccgt ttctgcacgt agataatgat gtgtttatct
     4441 ggcaaccttt cgaggacagg gtgatgtctg ccccgctggc ggcgcagaac ctggaaggtg
     4501 ctgcatcttc ctacgccgct acgtttaatg atatctgtga taaattcccg tatatacgtc
     4561 cgggtatcag ggagctgtac ggcaagaaaa tcatagaatg cagtaacgca ggcattctgg
     4621 gcggatcaga tatcgctttt ttccaggagt acacagcaga ggtgtttcac ttcctgaaac
     4681 agaacgaaga acacctggac catcatatga tgcatatgaa cagtacttac atcaatgtgg
     4741 tatatgaaca ggtgtttttt tactggatgg cgcaggcaca gcagcgggag gtcacctacc
     4801 tcttccccga tgtgattgac ttccctaact atatcggtta tttccatgag gcattgccga
     4861 ataagaattt tgtacactgc ctgggtgttt tcaaacagat cagacatgtg tgcaatatgc
     4921 tgtcgcggga attgaagcac cgttatcccg aatattatta tcgcatccag gaactggttg
     4981 catcttctga aatctaaaaa agttaaacgc atggaaatat tgaatacagc ggcaggagtg
     5041 tcgccggcag cataccggat ctgtcagtct atagatcgga tggaagcacc actgacgggt
     5101 gcggatatta aaaaagtggt gcctgccaag tgtgctttta tgctggagct gttccggcgc
     5161 accggtgagc aggcggtatg gaacgatctg ataacgttgg ccgcacaatt aaaaacttac
     5221 caggaatccc ctggctataa ttatacgctt tatggcgggc ggatgggcat cgcctggttt
     5281 tatctcgggc tatacaggac cagcggagaa agccaatggt tgcaggaggc gaggcagata
     5341 gcgatggatt acctgcaggg agaatccttc cggtatagca tcattgctac cagcggtgtt
     5401 gccacggggc tggctggtat cctgctggtg ctgctgcatg tgtacaagga aacgcaggac
     5461 ccggaaatac tggaagggct ggaaaagatt gtgctgcaac ttgccttccg tgcaaagcag
     5521 gggagaaaag gaatccactg gggaaatgcc actaattgtg aaggtgccaa cacaggcttc
     5581 aaaaatggcg ctgccggtat cgcgctggta ctgtcggaag tcagtcgtta tttttcgtcc
     5641 ggcatactgg aggcgctggc tgccaaagca ctggaatatg aagcggatta tcaggcagat
     5701 cccgtaagtg ccgggtgtcc gggcagcgag gcgccgtatg gggaagggtt ctttctgctg
     5761 aagtatatgc agataatgga aaccgaaaac ggcgatggtg gcctgccgga aggattgccg
     5821 ctacggtccg ttttcgggcc ggagggatac gacatactgg atgcatactt gcaatcggcc
     5881 ttccgccgga catgttcgtt gttgaaatcg ctgcggccga atgtcctcca ggcgtattac
     5941 agtgaatatg gaataccgga tatcgcggca tttgaaaaat acatagaagg ctggctggca
     6001 gcggtggagg agcataccga tgtaacagct gtcagggtgg aatttgaaag agaacagttt
     6061 atcctgtccg tcaggcgttc actgggattt agatgccgtc cggtggcgga tgacgaagcg
     6121 ggcgtagaac agctggaggc gcagatgccg ctgagcaccg agcggttttt atcactgcgg
     6181 cttgtccatg ctcccagtgt gaggacacgc agctgggagg aaacgatgga cctgtcccgc
     6241 gtgctcaccg tacccgagtt tgcatcattt ttccagcatt acggtgcgcg tttctgtatt
     6301 tgttatcttt cccttgacga taccttacag gatatcaatc ctggaattat caggctggta
     6361 ttcgaacagt ttgaccagcc cgttaccatc agggaagcgg cacaacgcat tgtaacgttt
     6421 atacagcagc agccggcgcc tgcattggcg ttgctcaaag atcactacta tgtgaccgac
     6481 gatgaacagc tcttcgggaa aatagtaaac ctggtgatcg atggcgcacg gctccatatg
     6541 gcggaaggta ttctggtcgc aacctgattc gtaattatat cgtagtaaat tattttgaaa
     6601 agcttctttt ttctaatttt attgcataaa ttgaaataca attccgaagc aactttgtaa
     6661 acctgacacc cttttttaat cattgatttt caacttgcag tagcgcaaag acgtttttac
     6721 tgtagcgtta gctctgtctt tcccggttac cctatttccc ttgcacatcc gggtttccca
     6781 acataaaaat ttactcattc aattgcatat gccatgatgg aagatttgta ttatctcaag
     6841 ccaaatctgg tgatcgaacc attatttaaa agatggtatg cgtggtcata cctcattcca
     6901 ccagcgactg ccgcgcgaaa tgttaccggc cgccatatga agatcatcaa ttcgtatata
     6961 caggcgccac agatacacat ggaagccgta cgtaacccca aaatgaaagg tggaccgttt
     7021 atggacttcg ggcgaaacag ggtggaagaa gtacgcgcgc tgcgggagga tacattgtca
     7081 tcccagcagg acctggtagc gctctccgac gcattaaaag agctcgatca gttgctgaaa
     7141 gaacatgcca aaggatattc cctggaaccg ctgtacgcca aagtgccgga tattctcaaa
     7201 ggatatgtgg aacttaacta tgacctgaac aaccagccgt cattccgcat cgtggagtcc
     7261 ctgctctata aaagcaaata ctaccaggaa caattccaga gtatcgcgct atgggtcaca
     7321 gaaaacgatg aaagaccttt tgtgctcagt actccccggc tggacgagcc caacgtgctt
     7381 cacctgccgg tagctttcaa tgaccgactg atcgacgaaa tagcccgtat gaaacatacg
     7441 cctaacacga tcagctacct gaaagaactg ctgaatgttt ccaaagagga cgaagcgctg
     7501 ctggaaacct ttttcacaaa agatgcgcct cctccatacc agcgctatga aggcgacaag
     7561 atcaggatgc gctatttcgg gcatgcctgc atcctcatag aaacaaaaga ggtgagcata
     7621 ctggttgacc cgcttattag ctattacgga tacaatacgg agctcgcccg tttttccgat
     7681 atgcatttgc cgcctgtaat tgattatgtc ctaatcaccc ataaccatca ggaccatata
     7741 ttgtttgaaa cgttgctgcc gttgcgtcac cggatcagga atatagtggt cccccggggc
     7801 ggctatgggc aattgcagga ccccaacctg aagatggtgt tgcaacaaac cggttttaaa
     7861 aatgtactgg agctggagga aatgggtacc ctggaaatgg gtgattgtac catcaccggt
     7921 attcctttct tcggagaaca ctccgatctc agcattagta cgaagatctg tcactacctg
     7981 cagataaacg attttaaaat catgttcgcg gcagattcat gtgtggtgga accccgcctg
     8041 tatgaacacg tgcaaaagga aataggtaat ctcgatgtat tgttcctggg catggaatgt
     8101 gacggtgcgc cgctaagctg gctgtacgga ccgttactta ccagggacct tcccagggat
     8161 atggatgctt ccagaaggct tgccggatct aatttcgaaa gaggaagcgc cattgtcgat
     8221 atctttcagc cggcagaatt atacgtatac gctatgggcc aggaaccctg gctggagttt
     8281 atcagcagca tcaaatacac cgatgaatcc aaccctatcg tggcctccaa taagctgatc
     8341 agcgaatgca aagaaaaagg cctcgccgct gaacgcctgt tcggtgaaaa agaaatactg
     8401 tataacaaac acaagtctcc cgcaaccgca caccccgtat tatagaagca ctatcagcca
     8461 cggctccctt ttccccttaa ttccaacaga tttatggcaa aacaaaaaat ggaatccctg
     8521 atggacaggg tcagggcaca ctttgcatat atgaaggagt ttttttccga atacaatgca
     8581 cagctggggg aagatatgcc ccggcagtta ccctcgttta cagacgagga gatgatgatt
     8641 tactgtgggc atccggaggc gcaagcctcc gggccggcgg cttcccctga agaaccgccc
     8701 gcagccaaat gagccacagg ttaacctctt ttgttgaaaa taaaaagtat gaaggtgagt
     8761 atcgaaaaca ccgcccacaa cctacgcatt tatatactgg atgaacatga cctgctggtg
     8821 cctgtcggtg tcgcagggaa gatatgtgtc ggctacgacc atttgtccgc gatagaaaaa
     8881 tattttcccg gcggccctgc acatagcccc acgccggacc ctttccggaa aggcgcatgg
     8941 ctttgcagga ccggtgatac cggacgatgg ctggacaccg gccgcctcga gttgctgaca
     9001 gataatcata taaccgatac cgttagtgcc ctgccggatc cggccgcaac aacctttgaa
     9061 acaccgcgta gcacatttga gcagcagttg ctcgatatct ggcggagcgt attgggaaaa
     9121 caggagatca gcatccacga cgattttttc cgctccggag gacacagcct taaagcggtg
     9181 cagctctttg cgcgcgtacg ccagctgatg gggctgtcgc ttcaaatgaa agatgttttt
     9241 acacatacga ccattgccgc ccaggctgcg ttcctggaga aagccgccac cagccgcgaa
     9301 agtggcatcg ttcgcgcgcc gcatcagagc agctatcctc tcagccacgc ccagcgccgt
     9361 ttctggatgc ttagccagtt cgaggaacgc tcccgggctt accatatcgc taacgtatgt
     9421 acgttgaaag gacagctgga taaaaaggcg ctgcaacggg cactctcgtt tgtattaaac
     9481 aggcatgaaa gcctgaggac cgtattccgg cttaatgaag caggagatgt ccgtcagtat
     9541 gtgctgccgg tctgggaggt ggcatgtgcg ccgcgttacg aggatatcac cggtagcccc
     9601 gataccggcg cggcgctgcg tgctatcggc gatcacgaac agctggctgt ttttgacctc
     9661 agcactgctc ccttgttcag gttgacggtg gtaaagaccg gtgatgatga acatgtgctc
     9721 ttttacacca tgcatcatat tattagcgat ggatggtcta tgctggtatt gctgagggac
     9781 gtaacggccg cttataacgc actgcgggta tccgctttgc cggagctgcc gcgcctggac
     9841 atacaatata aagattatgc ccactggcag gagcaatacc tgcaaggcga tacactggct
     9901 gccctggagc attactggat gaatcaactg agtggtgaat taccggtgac ggaactgccg
     9961 ctcgattatc caaggccgtt ggtacagtcc tttagcggcc atagtatgat tcgcgagatg
    10021 ccggccgtac cggcggcggc tttgcggaaa ttatgccaca tggaaaatac cacgctcttc
    10081 accggcctcc tgtctgcatt gtctgcattg cttttccgct atacaggcca ggaagacatg
    10141 atcatcggga caccggtggg agggagggaa caactggcgc tggaagacca gatcggcgta
    10201 tatctgaata cgttgcccct ccgtatgcaa ccgcagggcg acgcttcctt cagttcgttg
    10261 ctgacgaagg ccaaggaggc gctgctgggc gcatatgaac atcaggctta tccgttcaat
    10321 atgctgacgg acaaactggc gccacccgta aatatcggga ggtcgccttt attcgacgtg
    10381 atggtggtga tgcaaaacca ggaaaatatt acgctcgata atacgccgga ccaccttgag
    10441 ggcataacaa ccggaggcac acaggaattt gctttgcaaa ccagccaggt ggacctcacc
    10501 tttaccttca cagaaaggga tggtaagctt tttctgcaga taacatacaa tactgcgctt
    10561 ttcaaagagg ccaccatcaa ccgtttgttt acgcattttt tcaatcttct ccgggaggtg
    10621 accgcctgcc ccggacaaca tatttgtttc ctgaaatatt tatctgacga agaagaacag
    10681 caacagctct acacatttaa tcataccgca gtcgcctatc cgtcaacact aaccatcgca
    10741 gacctttttg aggcgcaggc ggatagtacc ccggacgccg tcgccctggt gtatgaagac
    10801 cagcgaatga cttaccggga attggacgat gcggccaaca ggctggcaca tcacctcatg
    10861 gacagctatc acgtgaaacc ggatatgctg atcggtgtaa tgatggataa atcagcgctg
    10921 atgatgatcg gcatattggg cattctgaaa gcaggggctg cctatgtgcc ggtagaccgc
    10981 agttatcctg ccgcccgcgc aggagcgctg ctacaggacg ccagtgtgca gctgttgata
    11041 actgactctg ctgccgtatt tgacctgatt gaatattatc agggagatat aatggcactg
    11101 gacctgcagc tggacagttt acctgccagg gaagggcgcc ctgcccggca ggccggcccg
    11161 gctcatctgg cctatgtgat gtatacctcc ggttcgaccg gtcgtccgaa aggggtgatg
    11221 gtgacgcatc agagcgtggt acgactggtg aagaataccg gaattgtagc tttctccgga
    11281 caggatgtgc tgctgtctac cggcgcagtg tcattcgatg ccgtaacgtt tgaatattgg
    11341 ggaatgttgc tgaatggcgg ccgtttggtg ctgaccggca gggaaacgct gctcgactat
    11401 acgctgttgg gtcgcctggt aagaaaggag gcagtgacga tgatgtggtt cactgcatcc
    11461 tggttcaatc aactggtgga cgccgatgca agcctgtttg caacccttgc cgtggtcctg
    11521 gcaggaggcg atcgcttgtc tccgcatcat atcgggaagt tgcgaacatt atatccgtca
    11581 ctggtggtga ttaacggtta cgggcctacg gaaaatacaa ctttctctgc tacgtggcag
    11641 gtgacggatg aagacgtgga agatattccc atcgggcttc ctgtcagcaa cagtacctgt
    11701 tacatcctgg atgccaaccg gcagttgcta ccgctgggcc ttgccggcga gctgtatgtc
    11761 ggcggtgacg ggctggcccg cggatacctt caggccccgg aactaacgga aacacaattc
    11821 atcccgcatc cttttgttcc gggagaacgc ctctatcgca ccggcgacat gtgccgttac
    11881 agaccggacg gcgtaattac tttcctcggc cgcaaggatc agcaggtgaa gatacgcggg
    11941 caccgcgtgg aaccggcgga agtggcggcg gccatcagcc gggtgacggg tgttacccag
    12001 gcggtggtaa cagtcatcga cctgccggga aatgataaag gcctggctgc gtattttact
    12061 gcgctgccgg gaacggacgt ggatatggtc agcgctgcgt tgaccacact cttgcccgaa
    12121 tacatgcagc cacaggcaat gatgctgctg gaccagtttc cgctgaacgc caacggaaaa
    12181 gtggccgcgg gcgaattgcc tcctccggat atgacggcgc tgcggggaac aacggccgct
    12241 tacctggctc cccgtaatga aacagaggaa cgcctgtccc atatatggga ggaagtcctc
    12301 gagcggaaaa acatcggtgt caacgatcac ttttttgacc tgggaggcca tagcctgaaa
    12361 gcgatacaac tgatcagccg gatcagaaaa gaatggtctg ccgatgttca gatcaaagat
    12421 attttcagtc atccccggct ggcggaaatg gctgccctga ttgcagtggc gggacagcag
    12481 gccgtagaag agattcccgc gctgccgcct tcggagtgct atgttttgag caatgcccag
    12541 ctccgttttt gggtactcag ccgcttcacc gacagttccc tggcttataa tatggcgatg
    12601 gggctccggt taaacggacc gctggaagaa gcgctgctga aggctgctct gcataccgta
    12661 gtaagcaggc atgaaagcct gcggacggtg ttccggcaaa caccatcggg agaagtaatg
    12721 cagttcgtac aaccggcgga agagattacg ctgaactgga gctatcggga tatcagcgga
    12781 gaaccgcagc cggagcaggc actgaaaact atttatgcag aagagcagct gagacctttt
    12841 gatctcgggc aggggccgct gctgaggacc atattggtaa aaacaggacc caacaaccac
    12901 gctttttttt ataccatgca ccacatcatc agcgatggct ggtctatgca ggtgcttgca
    12961 aaagaagtgg tgagcattta taatgccttg ttacatggca gacttcccga tctgccgcca
    13021 ttgagaatac aataccggga ctacgccgcc tggcaacagt cacggctgga ccaattacag
    13081 caacaggagg attactggat gcgtcagctg gaaggcgacc tgccggtgct ggacctcttt
    13141 cccggtaaga cccgcccacc gatacaaacc catcacggtg atagcttgtc tgtcaccttg
    13201 ctgcagggca atatggaaga actataccgg tattgcaacc gggaagcggt tacccctttt
    13261 atgctgctgc tggcggctat caaaggcctg ttctaccgct acagcggaca ggaagacatt
    13321 atcgttggca tacctgtagc aggccgtgaa cagcaggagc tcgaaaacca gatcgggatc
    13381 tatctgaata cgctgccgct gcgtacacgg ttcaatgctg cacagagttt ccgggacttg
    13441 ttattgaaag aaaaggaagt gttgctggaa gcgtatggca accaggaatg tccgtttgac
    13501 cggttgctgg aattacgcaa ggtgaacagg gacattagcc gctcagcttt gtttgatgta
    13561 ttggtggtat tacagaatca gagcaacacc aatatatata gcggagatga cggaatggag
    13621 gggctaacgg ccagctatat cgatgggttg aaagcagaaa ccagccagtt tgatcttact
    13681 ttttccttcg cagaaaccag tgagggaatt cagctgtcgc tctcttacaa tacagacgtt
    13741 tttgaacggg aagaaatcgt gcgcttatcc ggccactatg cgcagttcct ctctgctgtg
    13801 gtgaaagatg ccggagttcc gttgagcagg gtggattata tcagtgaagg ggagaagcag
    13861 ctactgctgc aaactttcaa cgacaatagc gttgtggtac atgaaactat aacggtaccg
    13921 gatatactgg caatgcatat gcaagggcag ccggatgctc ctgctgtcac ggatgaaaga
    13981 gggaccgtca cgtaccgtat gctggaaaga atggccggca atatggctta ccggctgcaa
    14041 accgcctatg gcgtggaaaa gggcgacctc gttatgatac tggcagaccg ttcctccttg
    14101 tttgtagcag ctattcttgc tatctggaaa tgcggcgctg cctatgtgcc cgtcgatcct
    14161 gattatcctg cctcccggat acaggcaatt ataaatgctt ccagtcctgc tgcggtaatc
    14221 tgcgatgaaa aataccaggt cctggccggc gggtttgcgg cgctgataaa tcttttgacg
    14281 gcagacggcg aagaaaatat accaaagccg gtacacatta tgccggccga tctggcctat
    14341 gtgatattta cctccggttc caccggcgaa cccaagggag tgatgattga gcatcaggga
    14401 atgctcaatc acctgtatgc gaaaacggaa agcatggaga tgtcggctgc cagcgtggta
    14461 gcccagaatg cttcccagag tttcgatata tctgtatggc agttttttgc ggcgctgata
    14521 acgggaggaa ggaccgtcat atacagcgat caggagatat ttgagccgct ggcctgctgg
    14581 gaaaagatac gccgggaagg agttaccatt ctggaggtgg taccgtctta cctttcgctc
    14641 ttactggatt tactggcgca gcaggaagaa agacctgtgc tgtcattgaa ataccttgtt
    14701 gttaccggtg aaacgctcaa agcggtattg gtaaggaagt ggtttgagtt ttatccgcat
    14761 gtgccgatgg tcaacgccta cgggcctacg gaagcatcgg atgatatcac ccaccatttt
    14821 atgacggaag cgccgctgac ggataatatc ccgataggga agccggtaag gaacatgaac
    14881 atctatgtgc tcgacgccca ccggcaatta tgccccgtgg gagtagccgg cgagatttat
    14941 gtggcgggca ttggcgttgg cagggggtac ctgaacgatc cggataaaac cgcaggcgcc
    15001 tttatggata accctttcag taaagctgct tcggagagaa tgtacaaaac aggggacgtc
    15061 ggaaggttcc tgccggatgg gaatatcgaa ttttatggaa gaaaagacta ccaggtaaaa
    15121 atacggggaa acaggatcga gccgggagaa atagaaagcg tactgctacg gcaggaatct
    15181 gttaaagcag cggaggtgct gcctatggaa ggcgctgatg gcaggactat gctggtcgct
    15241 tatgtggtgg cggtcggcga tgaagtggcc acccggctgc gtgatcacct ggcggggctg
    15301 ttgcctgact atatggtgcc cgcccacatt atagccatcg cgcagatgcc gcttacaccc
    15361 aatggaaaaa ccgaccggcg ggcattggaa aaaatgctgc cgctggaggt acatagccac
    15421 aaaaccggag agcctcccgc agatgacatg gaggcgaccc tggtgaatat ttgggaagaa
    15481 gtactgggcg tggaagaaat aggcgtcaat gacagcttct tcgaactggg aggacacagc
    15541 cttggcgtaa tccggatatt aaatgctgtt cagcaacagt tcgacgtgaa agtagatatg
    15601 agggaactgt ttaaaaggcc cactgtgcgg caactggccc aggaaatcaa gctgttgcac
    15661 gctttaaggg aaccctcggt tacaaccaat aatcatcata gcaaggaaat cattatataa
    15721 tggaaacagc gaaatttatc ctttacctaa agcgtatagg ggtcagtgtt agtctgtcgg
    15781 atggccagct gcgcctaaga gcagaacagg acatcccgga gcttgtgctg gccgaagtgc
    15841 gtgaaagaaa gcccgcatta atcgcattgt tgtcagaaaa actggaccag gcaggaagag
    15901 ctgatgttat tatacctgcg ccggaacagg aaagttaccc gctaagccat gcgcagcagc
    15961 ggttctggat tctcagccag tcggaagccg gctccagggc atacaatatt cccggcgtac
    16021 tgttgtttga aggggaactg gatatcgctg tgttttcccg ggcgctggat tttgtcatca
    16081 gccggcacga aagcctgcgc actgttttca ggcaaaacga atcgggagac atccggcagt
    16141 atattctgcc ggatgacgca tttccgctgc cgctgcagat cttcgacctg tctgacgaga
    16201 caaaccacga ggcggcatta accgctatgt ttgacgagga acaggaaact gtttttgacc
    16261 tggaaagcgg tccgttgcta cgtacgcgca tcgtcaggct gggtgcggcc cggcatgcgt
    16321 ttttttatac catgcatcat attatcagcg atggatggtc gctggtggta ttgacccggg
    16381 aaatcatcca ggcctacaac tgttataagc agggccatgg ccccgtattg ccgtctttgc
    16441 cgctgcagta caaagactat gcacaatggc agcattcgga gcagcagcag tcttattttc
    16501 tgcaacagga agaatattgg ctgcagcagt tttccggacc gttgccggta ctggaactgc
    16561 ctttcgcaaa gagacggcct gccctcagaa cattccgggg cgcctcgctg gcccgcccgt
    16621 tgtcaacccc gatgctcaac cagctgaaag acctctgtgt gaaggaagaa tgcacactgt
    16681 ttatggggct gctggcaggc ttgaatgcgt tattctttaa atacacgggc caggaagata
    16741 ttatcctggg tacaccggtg gcaggaagag aacatccggg actcgaagac cagatcggat
    16801 tatatatcaa cagcctggca ctgcgtaccc gttttgaggc ttctgacagc ttcctttctt
    16861 tgttgagaaa ggagaagacg gtgctgataa acgcataccg gcatcaggca tatccctatg
    16921 ataagctggt ggcgcggctt acgcctccga aggataccgg ccggcaacct ttgttcgata
    16981 tcctggtggg gatgcaaaat caggcgtccg ccaatatcta tgacagaaag gccatattcg
    17041 acggcctgct ggtatctgtg ccggaaggaa tgcgtacggc cggcagccac ttcgatgtta
    17101 gtttcacttt tgtggaagcc gcaggcggac tggaactggt agtcatttac aatacggaca
    17161 ttttcaatga ccgggatata tcggacctgt ttgactgtta tcaggaatta atgttgcacg
    17221 cagttggcga ccccggtcag cgactaagca gcttgtcctg gattggggcg gcggcacagc
    17281 agcagctgga acctttcagc ggtatacatc agttgccgca actgccggct gctatgatgg
    17341 cgcccgacct ttttgaggcg caggcccgcg ccaccccgga ggctgtcgca ctggtgcatg
    17401 gcagccggaa agtcagctac cgcgagctga atgaagcggc caaccggata gcgcattacc
    17461 tgcgggaaaa acaacaggtc aaacccggac agctggtggg cctgatgggg gaacgctccc
    17521 ctgaactggt ctccggactg ctgggcatct ggaaggcggg agcgggttat gtaccgctgg
    17581 acgccggtta cccggaagaa cgtattgtac atatgctaac ggatgcgggt atacgactgg
    17641 ta
//
