LOCUS       NZ_FUWZ01000004        20978 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000004
VERSION     NZ_FUWZ01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 675913
            Orig. end                         :: 696891
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20978
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20978
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20978
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10978](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10978)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(580..1125)
                     /locus_tag="B5D63_RS25975"
                     /old_locus_tag="SAMN04488128_104425"
     CDS             complement(580..1125)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS25975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_104425"
                     /product="hypothetical protein"
                     /protein_id="WP_078671774.1"
                     /transl_table=11
                     /translation="MEFIKICTAAIESVASVFRTVYKAINKRRSFIRRIKSKQQLQVSD
                     FIFNAHTANITQLEDILRKYITIVQRTKDQLRVHIYTSHNMSRSKQLAALHQLREKLLD
                     HYADYRTLFDSTPYGGHAHIVKHGLLNVILKLESLQPYNPEDLLEAINLISSDQEHLTQ
                     GIHRTVSRMQQNLQQAHS"
     misc_feature    1602..1619
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            1854..3665
                     /locus_tag="B5D63_RS25985"
                     /old_locus_tag="SAMN04488128_104426"
     CDS             1854..3665
                     /GO_component="GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA]"
                     /GO_process="GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017739.5"
                     /locus_tag="B5D63_RS25985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104426"
                     /product="type VI secretion system Vgr family protein"
                     /protein_id="WP_078671776.1"
                     /transl_table=11
                     /translation="MSLYTRTTFTIGDSRFSSFHSLKLSQTIDGHHTFEIQISYDWLSQ
                     LGKGLFTAGREFLGKEISITVTGVEAAAAQKPLQFNGVVTGINAGKESDGTHGFCVIKG
                     FSPTILLEDDPHIATFEMQSLREIVTLAMKGVSPYGSAPAVQPANTDPLKYIVQYKEST
                     HHFVSRLAARYGEWYFYDGQKIVFGNYSPKEISLTHQVDLIDFDLGFQVHPNNTRFTGY
                     EYRRNQVVENETSAQAAGQMNNYTAHMQDVSDKLYRKPSLHKLNHGFSSAAKETVDDFT
                     LLQKKGRQAQMVVLKGTSQHTALRIGDIISINESVFGQANHGRFVVTHLDHLCTENGRY
                     KNTFEAIPADTAMPRVDFRPQTGCEPQSAVVTDNNDPKGLGRVRARFRWQQQGSTPWIR
                     MIAPHGGSGKGFYFVPELGEEVWIGFENGNPEAPYVMGTAYNGDAKTDYGDPQNNIKAI
                     RTRSGHTIRLDDTEGAESITITDKSGNTIQLDTAGKNIHITAMETIDLTAKNINLKASE
                     SITVDAGENVETTAGSDVRVKAGDAYTCQAINITEEASEDIVQTAQDAMKLRSGTMSLY
                     TTLGDIKIIGSGTTVLQGNKMVKISKG"
     gene            complement(3744..4235)
                     /locus_tag="B5D63_RS25990"
                     /old_locus_tag="SAMN04488128_104427"
     CDS             complement(3744..4235)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024212.5"
                     /locus_tag="B5D63_RS25990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104427"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_078671777.1"
                     /transl_table=11
                     /translation="MNLVNELEELALATRLKRLSERLSQDISKIYKESGLEFEARWFLI
                     LELLVRQKQLSVTEISESLQLTHPAVVQFTDQLLAQGLIKTTPDSRDKRRRLISLSAAG
                     KQMHRKISPILEVIREENRKWLEQASASLLTVLGELEKSLDEKSMYKRVKISLLEQSDQ
                     "
     misc_feature    complement(4242..4256)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 20.1"
                     /tool="antismash"
     gene            complement(4255..6702)
                     /locus_tag="B5D63_RS25995"
                     /old_locus_tag="SAMN04488128_104428"
     CDS             complement(4255..6702)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF026255.5"
                     /locus_tag="B5D63_RS25995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104428"
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="WP_078671778.1"
                     /transl_table=11
                     /translation="MKRSYMFTFALLICVTTYINKAVSQTGNTFYSIKGTFATADNTPA
                     RDVVVQLLQATDKKLVKLEYTDAQGNFSFDHLPAGQYLLATQSMAYAPWLSAAVTLNKH
                     LQLGILRLQPATTTLKEATVTASKPFIQQQYDKTTLNVAGSISAAGSTALEVLEKAPGI
                     TIDQNDNIAMRGRQGVQVMMDGKLVPMSGQELANLLRNLSANQIEKIDLITNPSARYDA
                     AGNAGIIDIRLRKSHQSGTSGNMSLSYGQGIYPKITPSLNFNSKSKQLNIFGSYSYNYR
                     ELMNDLDIERQFYNAADQYSGGINYDNFFKLGFNNHNARLGADYNVSPDITIGIVANGI
                     FNKGDIRSSSLAESFDVQQQPTSSFVTKGDNHPQRNNGSINLNYKHKLDTSGKELSVDL
                     DYARFSNDELQNYHTSYFDLQQTPAKPDYRLFGNLSGDLSIKSLKADYSQPLKGIGAQL
                     EAGIKSSWVKADNDVQFYDRSSGTDIPDTGKSNRFKYDENINAAYLNASKKWTHLSVQL
                     GLRVENTIAKGLQVTNKENFDRNYTQFFPSGYVGYMFNKTHDLGVSVSRRINRPSYREL
                     NPFKVFLDPLTYSTGNPYLKPEITNAFELTHTYKEKYITKIGFSTTTDNILTVLSPDKE
                     PNSVIQTGHNLARYNYYNLSFSVPFSVGKWLNSSNEALAYYGEYKGDLANTHLNASRVS
                     FNLNSINSITIDPNTSMEVTATYNSRTYYGFLDVKGVWFMGIGAQRQLWKKKASLRLNL
                     SDVFFTNYTNAITRLTGYGETFFQRRDSRVLTLTFNYKFGGSTSGGGNRKAGGAEEEKR
                     RAG"
     misc_feature    complement(6726..6739)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            complement(6864..7334)
                     /locus_tag="B5D63_RS26000"
                     /old_locus_tag="SAMN04488128_104429"
     CDS             complement(6864..7334)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791219.1"
                     /locus_tag="B5D63_RS26000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104429"
                     /product="hypothetical protein"
                     /protein_id="WP_078671779.1"
                     /transl_table=11
                     /translation="MRYLYFILPGLFAANTLQAQSDTAGVKQTIDKMFTAMHNSDSVAL
                     RECFSSNAVFHTIDEHKGNTTVKNVSVERFSSVIAGTPKGDLEERITYGPVQIDDRLAS
                     VWTPYRFYHQGKFHHCGVNSFQLVKLGKEWKIQYIIDTRRKDKCEEDGAAAQ"
     gene            complement(7577..8542)
                     /locus_tag="B5D63_RS26005"
                     /old_locus_tag="SAMN04488128_104430"
     CDS             complement(7577..8542)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS26005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_104430"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_078671780.1"
                     /transl_table=11
                     /translation="MVNRKTRKTVPVPTALERLLDEILQEAASLKETDIQLSADKTAAA
                     WALVPEPKFNTNCTLMVLNDHLLRLLDAGRIQEASNIAGRWVADIESSQEPVGELRPYV
                     LFAASLLYLNKPTAAKTIIRMTRSYGARKPDFKGLPALYWDLFINTQMEDTVVMERFQQ
                     EVLQPQRQLPEIEAVELHPFLIDYMAPMVQQGHSAFAAGNYEKAARAWIRALKQIPEPQ
                     SEFGQSLTLNAAIGDAFFLLRDYQQALPYLEAAKANIAENGQVNAFVLLRLGEVLLELE
                     EHADAREYLLRAHTLGGEKLFENEAQQYKDFLQSYLKTST"
     misc_feature    complement(8628..8645)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.93"
                     /tool="antismash"
     misc_feature    complement(8670..8687)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            8871..10007
                     /locus_tag="B5D63_RS26010"
                     /old_locus_tag="SAMN04488128_104431"
     CDS             8871..10007
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="B5D63_RS26010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104431"
                     /product="cytochrome P450"
                     /protein_id="WP_159456170.1"
                     /sec_met_domain="p450 (E-value: 9.4e-23, bitscore: 75.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAENPVVYDPEFVFYYGVKGAWQIFSHKEAKQVLGDYNSFSNLF
                     IPNLGQNIMGRNLNQSDPPDHKKLRSLVAKVFVPSVISRHADWIRQQCEEIIEPLLEKG
                     EMDFIHDFAIALPNRVIAQLLGIPAEDHAQVHSWVTTIVTNVKTMEEMQASFAAQQQIA
                     NYLDKMIEMRRIEPKDDLISHLLASEVNGERLNNEDLLGTVVGMFLAGFETTSSLLGNI
                     AYTFCHHPEVLDHYLEHPEDFDNIINEVLRVLPSAKSMTRVAKHDLELRGQQIKKGDYL
                     NIWLISANHDPEVFPEPDKFDFRRPNHSDSLSFGHGIHYCFGVPLAKMETEIALKVVFS
                     RIRKLRIKEGARIEMTPSTIITGFTRLPVTFSAVGVYQ"
     gene            complement(10001..10978)
                     /locus_tag="B5D63_RS26015"
                     /old_locus_tag="SAMN04488128_104432"
     CDS             complement(10001..10978)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="B5D63_RS26015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104432"
                     /product="hypothetical protein"
                     /protein_id="WP_143313099.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-67, bitscore: 223.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQTETTAKIVIPRLHCPFPTSVSPFVELVATNTFDFLHKYQLLD
                     SPEEERYFARYKMAWMTCRTMPKANFELLCCIDNLYSWLFVLDEQLDHVKPSTAYIREE
                     NYLQQLIDGFSYVLKHKVSPIDNKFFHALADICVRLDALSRPSWQSQFLISVQATFEAA
                     IWEAKNNKNREKHPTVAQYMHMRLFFSAANIGTDINELATGVWLPMYVLQHPDMVHLTA
                     LARRVVCWANDLFSLRKELEHGDEHNLVMMLKYHHNTTLEEAVLMAASIHDNEIGEFVS
                     CRAAFPDFGEELNKRIQVYLDGLETMVAGFFYWSITDTPRYNPY"
     gene            complement(11074..12891)
                     /locus_tag="B5D63_RS26020"
                     /old_locus_tag="SAMN04488128_104433"
     CDS             complement(11074..12891)
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="B5D63_RS26020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104433"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_078671783.1"
                     /transl_table=11
                     /translation="MKAFNVFIRSLTHLGRSNFYEKELNYRITKINIVALLLIVLGSIF
                     GLTYWLTSGYLSILIATMLGNVLFALVLYGNKKKKHVAAGVALQVTINLSTLYFGSILS
                     VAVDPIWLTLFLLISCLSFIKVGRAQTYCLMFSAATLLFLEVNRAIHILPPMDFSPEML
                     SLIYYCTAFTVMTLTSISLVTLVHYNAKLFHTITVRNQQLTDLNQELHASNTRLEQQVK
                     DRTANLEKAVTAKNIYVRELTHELRTPLNAIYSIAQLKLLSGKEKSRSEKKVDEDLFIA
                     CRNLQTLINNTQDKCKLDAGNFDEIKKEHVLLYSWITNIVNIYQYFANEKRVKIELEVQ
                     ESFPDAIVEDSIKLTKIVNNILVNAIKFTRSNTAILLRIYRDDTHWYIAVKDQGAGISP
                     DRMATLFKEFTRTTINFAEGSGLGLNITHHLVRILGGTIKVHSEIDEGTEFVVSLPLVP
                     FAGEIKSATIDIKENNLISFEGKKILVVEDDIMTQRYLSLLLSKRGFSIMHADNGQEAL
                     LKAHNHPDAIILDMSLPGKSGKDVLKELKANPALRHIPVIAASADTDETNIDEIMLEGA
                     SAYMIKPIDFHILIDVLVKNLLTGAIVKN"
     misc_feature    13030..13045
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.66"
                     /tool="antismash"
     misc_feature    complement(13103..13119)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    complement(13127..13143)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    13294..13303
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(13410..14207)
                     /locus_tag="B5D63_RS26025"
                     /old_locus_tag="SAMN04488128_104434"
     CDS             complement(13410..14207)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012788780.1"
                     /locus_tag="B5D63_RS26025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104434"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_078671784.1"
                     /transl_table=11
                     /translation="MQLPLYQIDAFTDRLFGGNPACVMPLQEWLPDGLLLEIARENAVA
                     ETAFFIPQGDGFALRWFTPEIEMDLCGHATLAAAHAIRTIHAYNGDTLHFHSRSGLLKV
                     TFEGERYALSFPSRKPAPATLPVEIAESLDRMPVAVLKARDYVLVYNTETDIRQIQINR
                     QLLDRINLDPGGVVVTAPGEDCDFVSRYFTPQASIFEDPVTGSAHCSLIPYWRERLHKT
                     ELLARQLSDRGGTLYCTDEGATVKMAGYARTYFTGTCEVPGNQ"
     gene            complement(14236..15021)
                     /locus_tag="B5D63_RS26030"
                     /old_locus_tag="SAMN04488128_104435"
     CDS             complement(14236..15021)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS26030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_104435"
                     /product="hypothetical protein"
                     /protein_id="WP_078671785.1"
                     /transl_table=11
                     /translation="MGNRTYLTIRTAPEQQEVLFEGNNSLAYFWLLLLKKKDVEQVRPA
                     FLTLYAAGDTAETAEEQEDTYVDTDIRIPLAEALSNAAAHRPYIEKVYPSLLPLYDDWR
                     TYLASVPSHDQLLYIDLEEFSGFYANVNHFLEELLDFYQHVSANKAYFKPAISDTTGWE
                     AIGRKQFYTYSGHYRNTPEIVDYQQRSLPAKPLSTGYRILIGCWVVFSLALLAAGTYSL
                     GYFRPVWLKALMALLIITPLLLLAVGGLVWLMNKGTKTK"
     gene            complement(15310..17208)
                     /locus_tag="B5D63_RS26035"
                     /old_locus_tag="SAMN04488128_104436"
     CDS             complement(15310..17208)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018305.5"
                     /locus_tag="B5D63_RS26035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104436"
                     /product="histidine kinase"
                     /protein_id="WP_078671786.1"
                     /transl_table=11
                     /translation="MYIRRPSVLLIISLCCAVCGCQPRSAAPPPSAGQSTTTPPVVREL
                     QHLIDSGARWDGPQAAQRLSQLKNDALQAGAVASGYYYYLEGVHYWYADSNQAATNSFN
                     RMLPAKPADTGQLTDLIILQQLGLLQVRLASKIDDSTFTRLFHLISLAEQYQYAGSWRV
                     YDLAAEIYFRFGDYDKAETYAAMARDSYPETGDYFRLSLFMEERSRIYERRHQYRQALQ
                     YQDSALRYALQQPDTIRLATVYSALGVLYEKNGDKPRGHALMEKAFNIKEKINKVSFQE
                     YINYGQLHQEKKDYSAALHYLGKALEKARLAGNAGNLSAAYDAIRHVYYDKGDYKTAIS
                     YLDSAADMALAEQEDRQLRKIVEIQALNELKVQQHKTTDLSRQYNNQAIIVRQQQVILL
                     IITILLVLGLLITFLLIRQRKLVTQKMSIELEQRLLRSQMEPHFIFNTLSVLQSFIRRD
                     EKEKSVKYLNKFARLLRLNLENSRHNLVRLQQETEALENYLSLQAVRFDNLFGYTIHDI
                     PAEESSGICIPPMLLQPFVENAIQHGMRNIAHRGHISITLQLQGDRLHCIIEDNGQGLQ
                     PAKNKDKNSLSSIITQERLKILSIQTGKLASLTITDKAGEGRTGVRVTMIIPTQRC"
     misc_feature    17198..17211
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.02"
                     /tool="antismash"
     gene            complement(17219..17962)
                     /locus_tag="B5D63_RS26040"
                     /old_locus_tag="SAMN04488128_104437"
     CDS             complement(17219..17962)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="B5D63_RS26040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104437"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_078671787.1"
                     /transl_table=11
                     /translation="MIRTLIIDDEPAIRKDLEWLMKRYPDFVVLGSCGSIAEARIIIPN
                     TEPELLLLDIELADGTGFDLLQEFPDRNFRIIFITAYNEHAIKAIKFGAFDYLLKPVDE
                     EELMATLKRLLSENAVNTRTQMDITSGHLQPKKPALQNRIVLRSSQYLQVVPFEEILYC
                     QSDGSYTTFHLSDKRKVMVSRPIKEYEELLPESWFIRIHQSYIVNHHFIDRFLKDGILI
                     LKDGTEIPVSARKREYVRQFLMGDH"
     gene            complement(18419..18994)
                     /locus_tag="B5D63_RS26050"
                     /old_locus_tag="SAMN04488128_104438"
     CDS             complement(18419..18994)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012789375.1"
                     /locus_tag="B5D63_RS26050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104438"
                     /product="DUF1579 domain-containing protein"
                     /protein_id="WP_078671789.1"
                     /transl_table=11
                     /translation="MKAQYVLAAVIGCLLTVNTASAQMDSAAAHKAWMAYMTPGPEHQL
                     LAKTDGDWTTDMTFWKGPGAPPEKATGSCSNKMILGGRYQESRYMSDMMGMPFEGLGTT
                     AYDNARKMYLSSWIDNMGTGMMMMEGKWDATVNGIVYTGKSFDPSSQKTMELRQVIKFQ
                     DANNYTMEMYRMANGKEFKEMEIAFKRK"
     gene            19130..19618
                     /locus_tag="B5D63_RS26055"
                     /old_locus_tag="SAMN04488128_104439"
     CDS             19130..19618
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012792585.1"
                     /locus_tag="B5D63_RS26055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104439"
                     /product="hypothetical protein"
                     /protein_id="WP_078671790.1"
                     /transl_table=11
                     /translation="MKTASINELKKELAAVPPAQLAALCLRLAKYKKENKELLTYLLFD
                     ADDEQGYINAVKAEMDQGFEEMTGSNLHNAKKRLRKILRLVNKHIRYMGSKPAEAELLI
                     YFCEQLLESGLLRHQSTVLHNLYAAQLKKIVKVTVGLHEDLQYDLRRQVEPLLEVLKS"
     gene            19757..20602
                     /locus_tag="B5D63_RS26060"
                     /old_locus_tag="SAMN04488128_104440"
     CDS             19757..20602
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013429.5"
                     /locus_tag="B5D63_RS26060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_104440"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_159456171.1"
                     /transl_table=11
                     /translation="MQSNASAQPPGGKKRMPVLGIAASMDNDSLAGAAGFSCLEETVKR
                     MLAPAVSEDVFAANIERINKARCRIQTCNVFIPGYLKLTGPAVNEAWVLGYVDTVMQRA
                     EKAGIRLIVLGSGEARKIPEGYDPDMAKGQFIRLARKMADIAKKHNCLIAMENLNATET
                     NFVNTVAEACQVVTAIAHPHFRLTADIYHMLRENEPPANLLQAKGILVHCHIAEREKRS
                     APGTERQDFRPYLAALRSIGYNGRIMMECRWTDPAKEYAPAVAYLEAQLNEVYHISGKK
                     "
     misc_feature    20886..20904
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.65"
                     /tool="antismash"
ORIGIN
        1 agtacaaagt ccggaaactc ctgcaagaat cggctttcaa agtccattga cacttccgtg
       61 agctttatat gaataccgat ttctgaaagg gactgcttaa tcagttctcc tgcaaggtag
      121 tcgactgcta ccatcccctt gatggagttt agttttttta gttgtccgac cactttttta
      181 cgcgttagct gttgtagcca gcggagaaac agtttctcaa ccagtgcagg aaatgcacct
      241 ggttcaaggg tgttgccaaa tgaaacattg ccggataagg gcattatcgc agcaagtagt
      301 ttcgaaatcg gctcgggcga gcatcggtat aggagcacga agcaagtggg tgaggacttc
      361 cgaagcagaa gggaaatacg cctcgttttt accgtctgca gccatgagcg gctgttccat
      421 ggcagcaagg cgatttcata ttgaccggtt aaaatcgtcc gctttagttg ctggtgatta
      481 tgtaccacga ccgttgtaaa cgggtaactc ctgaggctct caacatagtg gctataaggt
      541 atggatgtct cgtccggatg aaagcaaagt acacgcatat caggaatggg cttgttgaag
      601 gttttgctgc atccgtgaaa ccgttcggtg tataccttgg gtaagatgct cctggtcaga
      661 tgaaataagg ttgatcgctt ccagcagatc ttccgggttg tagggttgta atgattccag
      721 tttcagaata acgttaagta gtccatgttt aacaatatgg gcgtgaccac cgtagggagt
      781 actgtcaaac agggtgcggt agtccgcata gtggtccagc aacttttcgc gcagctggtg
      841 aagtgccgca agctgtttac ttctgctcat attgtgggag gtgtagatgt gtactcgtag
      901 ctggtctttg gtacgctgta caatcgtgat atattttcgc agaatatctt caagttgggt
      961 aatgttggcg gtatgcgcat tgaagataaa atcactgacc tgtagttgtt gtttactttt
     1021 aatcctgcgt atgaaggacc tgcgcttgtt gatcgctttg tatacggtcc tgaaaacgga
     1081 ggcgacgctt tcaatggcag ctgtgcagat tttgatgaat tccatagtat aacagtttag
     1141 cgacagcgct gcggatgact aaagtaaata cgcatacggt ctatttctgc gtaaacaagg
     1201 ggcagatgtg ccaatatttc cagttgtatg cgatgaaagg aagctataat atcgttagcc
     1261 tcagcggaaa aggaaatttc gtcatccggt agcgaaagga agattgcctt gttaatacgt
     1321 tgccctattt tgtgtagttc ttctgaaagg tgtgttctgc ggactattag tatggcggac
     1381 tttaatctgt gtatatccat tgcggcattt ctccagtcag acacttccat ggaattccgg
     1441 atagcgttta tgcacagagg tacgctatcg caataggttt caaatacaat cagtatttca
     1501 tcaatgctgc tatacagatt tcgcaggtat tccccatcaa aatgctcact aaactcgaat
     1561 acaggatcat gactcattta atatcaaatt gacaccagca atatcctttt tagcgggcat
     1621 ttttctgttt aacagatcca aaaagaggaa gattaacaaa acagatttaa tatttatata
     1681 atgtgatgat cgtttcccga aaaaccttat cttaggattc cgaagcagta cctgtttttg
     1741 ttaaaccatt tctctatgac aaaatatttg ccttaaccct gcagattgtt tgttgacagc
     1801 tggcacacga ataagctgct ttgtatcata tcaccttata aaaaccgcgg cacatgtctt
     1861 tatatacccg aaccactttc accattggcg acagtcgctt ctcttctttt cattccctga
     1921 agctgtccca gaccatcgac ggtcaccata cttttgaaat acagatcagc tacgactggc
     1981 tgtcacagct gggcaaaggc ctctttacgg ccggcaggga gttcctggga aaagagatca
     2041 gtatcaccgt caccggcgta gaggcggcag cggcccagaa accattgcag ttcaacggcg
     2101 tagtcaccgg tatcaacgcc ggcaaagaga gcgacggtac ccacggcttc tgcgtgataa
     2161 aaggtttcag ccctaccatc ctgctggaag acgaccctca catcgccacc tttgaaatgc
     2221 agtccctccg ggaaatcgta acgctggcta tgaaaggcgt aagcccctat ggcagcgcac
     2281 cagccgtaca accagccaat accgacccgc tcaaatacat cgtgcagtac aaggaaagta
     2341 cccatcactt tgtcagccgc ctcgcggccc gctacggaga atggtacttc tacgatggcc
     2401 agaagatcgt cttcggcaac tactcaccca aagaaatatc cctgacgcac caggtagacc
     2461 tgatcgactt cgacctcggc ttccaggtgc atcccaataa tacccgtttt acgggatatg
     2521 aatatcgccg taaccaggta gtggagaacg aaacttccgc gcaggcagcg ggacagatga
     2581 acaattacac tgcccacatg caggatgtca gcgataaact gtaccgcaag ccttccctgc
     2641 ataaactcaa ccacggcttt agcagcgcgg ccaaagaaac ggtggacgac ttcaccctgc
     2701 tgcagaaaaa aggccggcag gcacagatgg tggtcctcaa aggcaccagt cagcacacgg
     2761 ccctgcgcat cggagatatc atctccatca atgaaagcgt cttcggacag gccaaccacg
     2821 gccggtttgt ggtcacccat ctcgaccacc tctgcacaga aaacggacgc tataaaaaca
     2881 ctttcgaagc tatacccgct gataccgcca tgccccgcgt ggattttcgg ccgcagaccg
     2941 gctgcgagcc gcaaagcgct gtcgtcacgg acaataacga cccgaaggga ctgggccgcg
     3001 tacgcgcccg gttccgctgg cagcaacagg gatctactcc ctggatacgc atgatagccc
     3061 cccacggtgg cagcggcaaa gggttttatt tcgtgcccga actgggagaa gaggtatgga
     3121 taggcttcga aaatggcaac ccggaagcgc cctacgtgat gggaacggcc tataacggcg
     3181 acgccaaaac ggactacggc gatccgcaga acaacatcaa agccatccgc acccgcagcg
     3241 gccataccat ccgcctcgat gacacggaag gcgccgaaag catcaccatc acggataaaa
     3301 gcggcaacac catccagctg gatacggccg gcaaaaatat ccatatcacg gctatggaaa
     3361 ccatcgacct caccgcgaag aatatcaacc tgaaagcttc tgaaagcatt accgtagacg
     3421 cgggagagaa cgtggaaacc accgcaggct cagatgtcag ggtcaaagcc ggcgacgcct
     3481 atacatgtca ggcgatcaac atcacggaag aagcatcgga agatatcgtt cagacagccc
     3541 aggacgccat gaaactgcgc tccggcacca tgagccttta taccacgctc ggggatatca
     3601 aaattatcgg cagcggcacc accgtattac aaggcaataa aatggtgaag atctccaaag
     3661 gttaacacat tcctctttca tacaaatgcc cggccaccat tgtcgtgacc gggcatcgtc
     3721 tttttcatag cttacgatcg ggactattgg tctgactgct ccaacaagct gatttttacc
     3781 cgtttgtaca tacttttttc atccagcgat ttttccagtt ctccgagtac ggtcaacagg
     3841 ctggcgctgg cctgttccag ccatttccgg ttctcctccc ggatgacttc cagtatggga
     3901 ctgatcttgc ggtgcatctg tttgccggcg gccgacaggg atatcagccg gcgacgttta
     3961 tcccggctgt cgggcgttgt tttaatcaat ccctgcgcca gcagctggtc ggtaaactgc
     4021 actacggcag ggtgggttag ctgcaacgat tcggatattt cggtaacgct caactgcttt
     4081 tgccgcacca gcagctccag tatcaggaac caccgcgctt caaactccag cccggattcc
     4141 ttatatatct tgcttatgtc ctgagacagg cgctcactga gccttttgag ccgtgtagcc
     4201 agcgccagtt cttccagttc gttcaccagg ttcatgcagc caatttacca aaaattatcc
     4261 ggcccggcgc ttttcttctt cagccccgcc agcttttctg ttaccgccgc cggaagtact
     4321 gccgccgaat ttgtaattga aggtaagcgt cagcacccgg ctgtccctgc gctggaaaaa
     4381 ggtctcgcca tagccggtca gccgtgtgat agcgttggta tagttggtaa aaaatacatc
     4441 ggagaggttg agcctcaggg aagctttctt tttccataac tgccgctgtg cgcctatacc
     4501 cataaaccat acgcctttta catccaggaa gccataatag gtacgactgt tgtaggtggc
     4561 cgttacttcc atggaagtgt tgggatcgat ggtgatgctg ttgatactgt taaggttaaa
     4621 tgaaaccctg ctggcattca gatgggtgtt ggccagatcg cctttgtatt cgccataata
     4681 ggccagtgct tcgttgctgc tgttcagcca ttttcctacg gagaagggta cactgaaact
     4741 aaggttgtaa tagttatacc gtgccaggtt atgccctgtc tgaataacgc tgttaggctc
     4801 cttgtccggc gacaacaccg tcaggatatt atcggtggta gtgctgaagc cgatcttggt
     4861 gatgtacttc tccttatagg tatgcgtcag ctcaaaagcg ttggtgatct ccggtttcag
     4921 ataggggtta ccggtagaat aggtcagcgg atcgaggaat actttgaatg ggttcagctc
     4981 gcgataggag ggccggttga tacgacggct caccgacacg cccaggtcgt gggttttgtt
     5041 gaacatataa cccacgtacc cgctggggaa gaactgtgtg tagttgcgat cgaaattttc
     5101 cttattggtg acctgtaatc ctttggctat ggtgttttcc acccgcagcc ccagctgtac
     5161 gctcaggtgc gtccattttt tcgacgcgtt gagataggcg gcgttgatgt tttcatcgta
     5221 tttaaaacga ttgcttttgc cggtatcggg aatgtctgtt ccgctgctcc ggtcatagaa
     5281 ctgcacatcg ttatcagctt tcacccaact gcttttgatg ccggcttcca gttgagcgcc
     5341 gatacccttc agcggctggg agtagtcagc ctttaaggac ttgatgctca ggtcgcccga
     5401 caggttgcca aacagccggt agtccggttt ggcgggcgtc tgctgcagat cgaaatagga
     5461 agtgtggtag ttttgcaatt catcattgct gaagcgggca tagtccaggt ctaccgacag
     5521 ttctttcccg ctggtgtcca gtttgtgttt ataattcagg ttgatgctgc cgttgttgcg
     5581 ttgcggatgg ttatcgcctt tggtgacaaa agaactggtg ggctgctgct gtacgtcgaa
     5641 agactccgcc aggctgctgg agcggatatc gcccttgtta aagataccat tggccactat
     5701 gccgatagta atatccgggg agacgttata gtcagcgcca agccgggcgt tgtggttatt
     5761 aaaaccaagc ttgaaaaaat tatcatagtt gatgcctccg gaatactggt ccgcggcatt
     5821 gtaaaactgt cgttcaatat cgaggtcatt catcaattcc cggtagttat agctgtagga
     5881 accgaatatg ttcagttgtt tgcttttgct gttgaagttg agggagggcg taattttagg
     5941 atagatcccc tggccgtagc tgagcgacat attaccactg gtgccgcttt gatggctttt
     6001 gcggagccgt atgtcgataa tgccggcatt gccggcagcg tcgtaccggg cggatggatt
     6061 ggtgatcagg tcgatctttt caatctggtt ggccgacagg ttgcgcaaca aattggcgag
     6121 ctcctgtccg gacatgggca ccagtttccc gtccatcatc acttgtacgc cttgtctgcc
     6181 gcgcatagcg atgttatcgt tctggtcgat ggtgatgccc ggcgcttttt cgagtacttc
     6241 cagtgcggta ctgcccgcgg cagatataga ccccgccacg ttgagcgtgg ttttatcata
     6301 ctgttgctga atgaatggct tgctggcggt gacggtggct tccttaaggg tggtagtagc
     6361 gggctgcaac cggaggatgc ccagctgcag gtgtttgttg agcgtgacgg cagccgacag
     6421 ccacggtgca tatgccatgc tctgtgtcgc cagcaggtat tgccctgcgg gcagatggtc
     6481 gaaggagaag ttcccctgtg cgtcggtgta ttccagtttg accagtttct tgtccgttgc
     6541 ctgtaatagt tgtaccacta cgtccctggc cggggtatta tctgccgtag cgaatgttcc
     6601 tttgatgctg taaaacgtgt tgcccgtctg gctaactgcc ttatttatgt aagtagtaac
     6661 gcaaatcaac agggcaaagg taaacatgta tgaccttttc atttgggggt ttttaaagca
     6721 aaaatagaac tattgttccc ctctgtctac aggtaatggt aagtacttac ataaattttt
     6781 attgccggct accggccttg atgagtggaa gcggggggcg gtttcaggag gtttaaaagg
     6841 ggattctgca gaagcatggt ctgctattga gcagcagcac cgtcctcctc gcatttgtcc
     6901 ttgcggcggg tatcaatgat gtattgtatt ttccattctt ttcccagctt caccagttga
     6961 aaggagttga cgccgcaatg gtggaacttt ccctgatgat aaaagcggta gggcgtccat
     7021 acggaggcga ggcggtcgtc tatctgtaca gggccatagg taatacgttc ctccaggtct
     7081 cctttgggcg taccggcgat cacggaggag aaacgctcaa cggaaacatt tttgacagtg
     7141 gtgttgcctt tatgttcatc gatggtatgg aagacagcat tggaagaaaa acactcccgg
     7201 agcgcaacgc tatcgctgtt atgcatagcg gtaaacatct tatctatcgt ctgttttacg
     7261 ccggcagtgt cggactgggc ttgcagggta ttagcggcaa agaggcccgg caggataaaa
     7321 tacagatagc gcatcttttt aaacctaaaa tattaaatct aaaatattaa atctaaaata
     7381 cattatttgg tctgtttctg atgcgcggct ttgaaatgat gccggatatg ctccacgaaa
     7441 tgctgtatca gcgaattttc cggtccaggc atgctgcttt ccaggtccgc ttccgcagcg
     7501 gcgtttgcag tggcagggta acgaggtccc tgtttttaag gtacggcgca atagcccagg
     7561 tagcaaattt cttttattac gtactggttt ttaaataaga ttgcagaaaa tctttatact
     7621 gctgcgcttc attttcaaaa agtttttctc ctcccagcgt atgtgcgcgc aagaggtatt
     7681 cccgggcgtc tgcatgttct tccagttcca gcaatacttc cccgaggcgc agcaatacga
     7741 atgcgttgac ctgcccgttt tccgctatgt tggctttggc ggcttcgagg tagggcaagg
     7801 cttgttgata atcccgcagg agaaaaaagg cgtcgccgat agcggcgttc agtgtgaggc
     7861 tttggccgaa ttcggattgc ggttcgggta tttgtttcag cgcccgtatc caggcgcggg
     7921 cggccttttc atagttgcct gctgcaaagg cgctgtggcc ctgctgtacc atgggcgcca
     7981 tatagtcgat gagaaacggg tgtagttcta ccgcttcgat ctccggcagt tgacgctgcg
     8041 gttgcagcac ctcctgctga aaacgttcca tcaccacggt atcctccatt tgtgtattga
     8101 taaacaggtc ccagtaaagc gccggcagtc ctttgaaatc cggtttgcgg gcgccgtagc
     8161 tgcgggtcat gcggataatg gttttggcag ctgtgggttt gttgagatag aggagggaag
     8221 ccgcgaagag cacatatggc cgtagttcgc ctaccggttc ctggctggat tctatgtctg
     8281 ccacccagcg tcctgcgatg ttgctggctt cctgtatgcg gccggcatcc agcaaacgca
     8341 gcagatggtc attgagcacc atcagcgtgc agttcgtgtt gaacttcggc tccggcacca
     8401 gggcccaggc ggccgcggtt ttatcggccg acagttgtat gtctgtctcc tttaatgagg
     8461 cggcttcctg caatatttca tccagcaggc gttcgagcgc agtaggtacc ggtactgtct
     8521 ttctggtttt tctgtttacc atagatgatg tgtaggtgta aaacaataac tgaagttaac
     8581 acattagaga tgtgctggtt gtcaattacg atcagcggta aatcagcata acatgcgctt
     8641 aacagggctt actcgtaaaa gtgatgtgat taacgctcgg ttaacactgc gactattatg
     8701 cgttatatag caatacaatc cgtattttgt ttattgtaac gatatactgt ttatcaccgt
     8761 tttttttgtt ttatcaccgt tatttatgta ccagcggtca ctgcatgtga tggccgcaca
     8821 aacgattgtc acttatgatt tctcctaatt caattccctg gtttgcaaaa atgagagctg
     8881 aaaacccggt ggtgtatgat ccggaatttg ttttttatta cggcgtgaaa ggagcatggc
     8941 agattttttc gcacaaggag gccaagcagg tcctgggcga ttacaattcc ttctccaatc
     9001 tttttatccc taacctgggg cagaatatta tgggcagaaa cctgaaccag agcgatccgc
     9061 cagaccataa gaaactacgc tcgctggtgg cgaaggtatt tgtgccgtca gtgatttcca
     9121 ggcatgcgga ctggatcagg cagcagtgtg aagagattat tgagccgttg ctggaaaagg
     9181 gagagatgga ctttatccat gattttgcca ttgcattgcc taaccgtgtc attgcgcagc
     9241 tactgggtat tccggcggaa gaccatgcac aggtgcacag ctgggtgacc accattgtta
     9301 cgaatgtaaa gacgatggaa gagatgcagg cttcttttgc agcgcaacag caaattgcga
     9361 actacctcga caaaatgata gagatgcgca ggatagaacc caaagacgac ctgatttcgc
     9421 atctgctggc gtcggaggta aatggcgaaa ggctgaacaa cgaagatctt ctgggtacag
     9481 tggtaggtat gttcctcgcc ggttttgaaa caacatcttc gcttttgggg aatatcgcct
     9541 atactttctg tcatcatccg gaggtgctgg accactacct ggagcatccg gaagattttg
     9601 ataatatcat caatgaggta ctgcgggtat tgccttctgc caagtccatg acgcgggtgg
     9661 ccaaacatga cctggagctg cggggccagc agattaagaa aggagattac ctgaatatct
     9721 ggctgatatc ggccaatcat gacccggagg tgtttccgga gccggataaa ttcgatttcc
     9781 gccgtccgaa ccattcagac agcctgagct tcgggcatgg catacattat tgtttcggag
     9841 tgccgctggc gaagatggag acagagatag cgttaaaggt ggtgttttcc cgtatcagga
     9901 agctccggat caaagagggg gcccggattg agatgacgcc gagtacaatt attacaggct
     9961 ttacgaggtt accggtcacg ttttcagccg tgggcgtata tcagtaaggg ttatagcggg
    10021 gagtatcggt aatgctccag tagaagaagc cggcaaccat tgtttccagt ccatccagat
    10081 agacctgtat ccttttattc agttcttccc cgaagtcagg aaatgccgcc ctgcaggata
    10141 caaattctcc gatttcatta tcatgaatag atgccgccat caacactgcc tcttcaaggg
    10201 tagtgttgtg gtggtatttg agcatcatca ccagattgtg ctcgtcgcca tgttcgagct
    10261 ccttgcggag agagaacagg tcgttggccc agcataccac tcttctggcc aatgcggtca
    10321 gatgtaccat gtccggatgt tgtaatacat acataggtag ccatacgccg gtggccagct
    10381 cgttgatgtc ggtgccgata ttggcggcgg agaagaacag ccgcatatgc atgtactgcg
    10441 ccaccgtcgg atgtttttcc ctgtttttgt tgtttttcgc ctcccatatc gcggcttcga
    10501 aagtcgcctg cacgctgatg aggaattgcg actgccagct gggcctgctc agcgcgtcaa
    10561 ggcgtacgca aatgtcggcc agcgcatgga agaatttgtt gtcgatcggc gacaccttgt
    10621 gtttgagcac ataggaaaaa ccatctatca gctgctgcag gtaattctct tcgcggatgt
    10681 aggcggtaga cggctttacg tggtccagct gttcgtccag tacaaagagc cagctgtaaa
    10741 ggttgtcgat gcagcacagc agctcaaagt ttgccttagg catcgtccgg caggtcatcc
    10801 aggccatttt gtagcgggcg aaataacgtt cttcttccgg actgtccagc agctggtatt
    10861 tgtgcaggaa atcgaaggtg ttggtcgcta ccagttccac aaacggactg acactggtag
    10921 ggaacgggca atgcagcctg ggaatgacaa tcttcgcagt agtttcagtt tggttcataa
    10981 acattgtgac aatcggtgat aaacaaaagg tacctttcgc gccggtagag cgcgataaaa
    11041 aagaaatgaa aaacggttga tatctgctaa atactaattt ttaacgattg ctcctgtgag
    11101 tagatttttg accagtacat cgatcaggat atggaaatcg attggcttga tcatataggc
    11161 gctggccccc tccagcatta tttcatcaat attggtttca tcggtatcgg cagatgcggc
    11221 gatcaccggg atgtgtctta aagcaggatt ggcttttagt tctttcagta catctttgcc
    11281 tgatttgccc ggcaggctca tgtccagaat gatggcatcc ggatgattat gtgctttgag
    11341 cagcgcttcc tggccattgt cggcatgcat aatggagaag ccacgtttgc tcagcagcag
    11401 cgacagataa cgctgggtca tgatgtcgtc ttctaccacg agtatttttt taccttcaaa
    11461 agagatcagg ttgttttctt tgatgtcgat ggtggcggat tttatttcgc cggcaaaggg
    11521 tactaacggc agcgatacta cgaattctgt accctcgtct atttcactgt gcactttgat
    11581 ggtaccaccc agaatacgaa cgaggtgatg ggtgatgttg aggcccaacc cgctgccttc
    11641 cgcaaagttg atggtggtac gggtaaattc tttaaacaac gtggccatcc tgtccggtga
    11701 aataccggcc ccctggtctt ttaccgctat gtaccagtgg gtgtcgtccc gataaatacg
    11761 caggagaatg gcagtattgc tacgggtgaa tttgatggca ttaacgagga tattgttaac
    11821 gatcttggtc agtttgatac tgtcttccac aatggcgtcc gggaaagact cctgcacttc
    11881 cagttctatt tttacccgtt tttcattggc gaaatactgg taaatgttga cgatgttggt
    11941 gatccagctg tagaggagaa catgttcttt cttgatttca tcaaagttgc cggcgtccag
    12001 cttgcatttg tcctgcgtat tgttgatcag cgtctgcagg ttgcggcagg cgatgaacag
    12061 gtcctcgtcc acttttttct cgcttctgct tttttccttg ccggacagca gtttcagctg
    12121 cgcaatgctg tagatcgcat tcagcggggt ccttagttcg tgggtcagct cgcggacata
    12181 aatatttttg gcagtaaccg ctttttccag attggccgtc cggtctttta cctgttgctc
    12241 cagtcttgtg ttactggcgt gtaattcctg gttcaggtcc gtcagttgct gattgcgcac
    12301 cgtaatggta tgaaacagtt tggcgttgta atgtaccaaa gtcaccaatg aaatagaagt
    12361 cagcgtcatt actgtaaaag ccgtacaata atagatgagg ctcagcatct ccgggctgaa
    12421 gtccatcggc ggcaggatat ggatagcgcg gttcacttcc aggaacaaaa gggtagctgc
    12481 cgaaaacatc aggcagtagg tctgcgccct gcccacttta ataaaggaaa gacaggagat
    12541 cagcaggaaa agcgtcagcc agatagggtc taccgctaca gaaagaatgc tgccgaaata
    12601 aagcgtcgat aaattgatcg ttacctggag cgccacaccg gccgccacat gtttcttctt
    12661 tttattacca tatagtacaa gcgcgaacag gacattgccc aacattgtcg caatcaggat
    12721 actcagatag cccgaggtga gccaatatgt caaaccgaag atcgagccta gtacgatcag
    12781 caaaagcgcg acaatattga tcttggtgat ccggtaattc agctcttttt cgtagaagtt
    12841 actcctgcct aaatgagtga gcgatcggat aaagacattg aatgctttca tctggattgt
    12901 aaatttttca tgtgaggtta cgctcgagaa acgtctttta gtaatggtta ctctgggtgg
    12961 ctttggactg gaaccgatga ttaacttcca tcccgcattt agctaaattt aacaaaaacc
    13021 tgttaaataa atgataaata tttccacata tttaaagatt aacaaatagc ttttgtaaac
    13081 ataacatccc aacctgaata atctgatgta aaaatacaat atgttattgt aataaactga
    13141 aaaccaaaat tttattttta tgtcgggaga taaaaagagc cgcctcggga gcagcaactt
    13201 gctccggagg ggaaaattta cgccctgtta agggagaatt gcgacgaaat caggtatccg
    13261 gaccagccga tatcggccgg cacagctgtc gtttattttt ttagcggacc accgggtttg
    13321 ctgaaagacc tcgtcaaact tttctactac cagcaccagc cggcgttaga ggaacgcccg
    13381 cagcgtgcca ggcagggggg acttattgcc tactgattgc ccggcacctc gcaggtgccg
    13441 gtgaaataag tgcgggcgta acccgccatc ttcacagtag cgccttcatc ggtacagtac
    13501 agcgtaccac cgcggtccga cagctgccgg gccagcagct cggttttatg aagacgttcc
    13561 cgccagtagg gaatgagcga gcaatgggcc gagccggtaa ccggatcttc gaatatggaa
    13621 gcctgcggtg taaaataacg ggatacaaag tcacagtctt cccccggagc ggtcaccact
    13681 acgccaccgg gatcaaggtt aatgcggtcc agcaactgac ggttgatctg tatctgccgt
    13741 atatccgttt ccgtgttata caccagtacg tagtcccgcg cctttaagac cgccacaggc
    13801 atacggtcca gcgactccgc aatctccacg ggcaatgttg cgggtgccgg tttgcgcgag
    13861 ggaaaggaga gggcgtagcg ttctccttca aacgtcacct tcagcaggcc gctgcgggaa
    13921 tggaaatgca gcgtgtcacc gttatacgca tggatggtgc ggatggcgtg ggcggccgcc
    13981 agcgtggcgt ggccacagag gtccatctca atttcagggg taaaccaccg taaggcaaac
    14041 ccatctccct gtggaataaa aaaggcagtt tcagccacgg cattttcccg ggctatctct
    14101 aacagcagcc cgtctggcag ccactcctgt aagggcatca cgcaggcggg gtttccgcca
    14161 aaaagacggt cggtaaaggc atctatctgg taaagcggca attgcatagt ttcttttttg
    14221 ttaaatgatg acgggctatt ttgtttttgt tcctttattc atcagccaga ccagcccgcc
    14281 aacggccagc aacaaaagtg gtgtgatgat gagcagcgcc atcaacgctt tcagccaaac
    14341 aggccggaag tagccgaggc tgtaggtacc ggccgccaac aacgccagac tgaaaaccac
    14401 ccagcaaccg atcagtatcc tgtagccggt ggacagtggt ttggcgggca ggcttcgctg
    14461 ctggtagtcc acgatctcag gtgtattccg gtagtgcccg gagtaagtat agaactgctt
    14521 cctgccgatg gcttcccagc cggtggtgtc agagatcgcc ggcttaaaat aggctttgtt
    14581 ggcagataca tgctggtaaa aatccagcag ctcctccagg aaatgattta cattggcata
    14641 gaagccactg aattcctcca ggtcgatgta caacaactgg tcgtgggaag ggacggaggc
    14701 gagatacgtc cgccagtcat cataaagcgg cagtagcgat ggatacacct tttctatata
    14761 gggccggtgc gctgcggcgt tgctgagcgc ttctgccagc ggtatccgga tgtcagtatc
    14821 gacataggtg tcttcctgct cctccgctgt ttctgcggtg tccccggcag catacagggt
    14881 aagaaaagca ggccttacct gttctacatc tttctttttc agtaacagta accagaagta
    14941 agcgaggctg ttgttgcctt caaacaatac ctcctgttgc tcaggagcgg tcctgatggt
    15001 taaataggtc ctgttgccca tgtgtgtaca tttgtcttgg gttttatgct atcagcatgc
    15061 aaaaatcatc cgtccggggt gtaatccggg ctcaccgtac caggctgtaa ggatactaca
    15121 cttttctatg ataaacaatg ttttttgggc gccttcccgg ctatctgctg tatgcgtctt
    15181 cccaatagct gttcatatta taatataagt ggtaaacccc gggtttggtt cacttgcgtg
    15241 gaaaattggc gcgtttgacg gcatcatggc ctaatttcca cctgcatccc ttttgcaggt
    15301 atccgctgat taacatcgct gggtgggaat gatcatggta acgcgaacgc ctgtacgtcc
    15361 ttcgccggct ttgtcggtga tggtgaggga ggccagttta cccgtttgta tgctcagtat
    15421 tttgaggcgc tcctgtgtaa tgatgcttga cagggaattt ttgtccttat ttttggcggg
    15481 ctgcaacccc tggccattgt cttcgataat gcaatgcagc cggtcgccct gcagctgcag
    15541 cgtaatagag atatggccac ggtgcgctat attacgcatg ccgtgctgga tggcgttttc
    15601 cacgaaaggc tgcaggagca ttggcgggat acagataccg ctgctttctt ccgccgggat
    15661 gtcatggatc gtatagccga agaggttgtc gaagcgtacg gcctgcaggc tgagatagtt
    15721 ctccagcgct tcggtttcct gttgcaggcg gacgaggttg tgccgggagt tttcgaggtt
    15781 aaggcgcaac agccgcgcaa atttattgag gtatttaaca gacttttctt tttcatcccg
    15841 ccggatgaag ctttgtaata ccgacagggt attgaagata aaatggggtt ccatctggct
    15901 gcgcagcagc ctttgttcca gctctatgct cattttctgg gtcaccagct ttcgttgccg
    15961 tatcagcagg aaggtgatca gcaggccaag gaccagcagg atggtgatga tcagcaggat
    16021 gacctgctgc tgacgcacga tgatggcctg attgttatac tgccggctca ggtccgttgt
    16081 tttatgctgc tgtactttca gttcgttgag cgcctgtatc tccacaattt ttctcagctg
    16141 cctgtcttcc tgttctgcca gggccatatc ggcggcggag tcgaggtagc tgatggcggt
    16201 tttgtaatcg cccttgtcat aatatacatg gcggatggcg tcataggcgg cgctgaggtt
    16261 accggcattg ccggccagcc gggctttttc cagggctttg ccaagatagt gcagcgctgc
    16321 ggagtagtct tttttctcct ggtgcagctg gccgtaattg atatattcct ggaagctgac
    16381 tttattgatt ttctccttga tgttaaatgc tttttccatc agggcgtgcc cccgcggttt
    16441 gtcgccattc ttttcataga gcacgcccag cgcgctgtat acggtggcga ggcggatagt
    16501 atcgggctgc tgcagcgcgt atcgcagggc gctgtcctgg tactggagtg cctgtcggta
    16561 ctgatggcgg cgttcgtaga tgcgtgaccg ttcctccata aaaagcgaca gccggaagta
    16621 atcgccggtt tccggataac tgtcccgcgc catggcggcg taggtctccg ccttgtcgta
    16681 atcgccgaag cggaaatata tttctgctgc caggtcatac acccgccagc tgccggcata
    16741 ctgatattgt tccgccagcg agatcaggtg aaacagccgc gtaaaagtgc tgtcgtctat
    16801 tttgctggcc agccgcacct gtagcagtcc cagttgctgc aggataataa ggtctgtgag
    16861 ttgaccggta tctgcgggct ttgcgggcaa catgcggttg aaactattgg tggcggcctg
    16921 gttgctgtcg gcataccagt agtggacacc ttcgagatag tagtagtagc cgctggcaac
    16981 agcgcctgcc tgcaaagcgt catttttaag ctgagaaagc cgctgggctg cttgtggccc
    17041 gtcccatcgg gcgccggaat caatgagatg ctgcagctcc ctgaccaccg gtggggtagt
    17101 ggtactttgt ccggcggacg gcggcggagc agcggaccgg ggctggcatc cgcagacggc
    17161 gcagcaaagg gatatgatca gtaaaacgga tggtctgcgg atatacatgc acaatctatt
    17221 aatggtcgcc catcaggaac tgccggacat actcccgctt acgggcggaa accgggattt
    17281 cagtaccgtc tttcaggatc aggataccat ctttcagaaa acggtctatg aaatggtgat
    17341 tgacgatata cgactgatgg atgcggataa accagctttc gggcagtaat tcctcgtatt
    17401 ccttgatagg ccgggaaacc attaccttcc ttttgtcaga caggtggaag gtggtgtagc
    17461 tgccgtcgct ctggcaatag aggatttcct cgaaaggcac tacctggagg tattgcgaag
    17521 agcggagcac gatacggttc tgcagcgccg gttttttagg ttgcaggtga ccgctggtga
    17581 tgtccatctg ggtgcgggtg ttgacagcgt tttcagacag cagccgtttg agggtggcca
    17641 tcagctcctc ttcatctact ggtttcaaca gatagtcaaa cgccccgaat ttgatggctt
    17701 tgatcgcgtg ttcattataa gcggtgatga aaatgatccg gaagtttctg tcgggaaatt
    17761 cctgtaagag gtcaaatccg gtgccgtcag ccagttcaat gtccagcagc aacagttccg
    17821 gttctgtgtt ggggatgatg atccgtgcct cggcgatgct gccgcagctg cccagcacaa
    17881 cgaaatcggg gtagcgtttc atgagccatt ccagatcttt acggatggcc ggttcgtcgt
    17941 caataatcag cgtacggatc atggtctcgg atatgggtta ttgctcattt tactaaaagt
    18001 aacaaaaaaa tcaggtatta ccggatggta atacctgtaa ggttatcaac aaagaataaa
    18061 aggccgacct aacagcttaa acataatagg gctctccgga gaacaaacta tatgactgaa
    18121 caatgcagaa gccggtgctg ccacggtgtt caccagaata tttttatttc atgcggaatg
    18181 cgcacttaaa cgttttacta agggaagaac tgaataacgc cggccccaac aatggcggcg
    18241 aaacaggcgg ataaatagcg gacgatcaaa gataacgcca cccattgtcg gaaggcttct
    18301 gaattaatat ccgtaccggt tttgtttata ttcgttttgg tagtaatgtg ttgcggggaa
    18361 aaacaggcgg cccctgcttt cacagcagag gccgccggag tatgttgacg ggcagcagct
    18421 atttccgttt gaacgcgatt tccatttctt tgaattcctt gccattggcc atgcggtaca
    18481 tttccatcgt ataattattg gcgtcctgga atttgatgac ctggcgcagc tccatggttt
    18541 tctggctgga agggtcgaag gattttccgg tgtagacgat accgttgacg gtggcgtccc
    18601 atttgccctc catcatcatc atgccggtgc ccatgttgtc gatccagctg ctgaggtaca
    18661 ttttgcgggc attgtcgtaa gcggtggtgc cgagaccttc gaagggcatg cccatcatgt
    18721 ctgacatata gcggctctcc tggtaacgtc cgccgaggat cattttgttg gagcagctgc
    18781 cggtggcctt ttccggcgga gcgccgggac ctttccagaa agtcatgtcg gtggtccagt
    18841 caccatcggt tttagccagt agctgatgtt cggggccggg tgtcatgtag gccatccatg
    18901 ctttgtgggc ggcggcggaa tccatctggg ccgacgccgt gttaactgtt aacaggcaac
    18961 cgataacggc agccaacaca tactgtgctt tcatagtctg aggctgttta gaagtgagta
    19021 aatggggtta ttgaagaagt gcaagttaac taattatgat acgtgcgcag gcttaggtgt
    19081 tgcaccatac tatttattaa ttgtattttc gggccgcaat aaaaccaaga tgaaaacagc
    19141 gtccatcaac gaattgaaga aagagttggc tgccgtgcca ccggcgcagc tggcggcatt
    19201 gtgtctgcgc ctggccaaat ataaaaagga gaacaaggag ctgctgactt acctgttgtt
    19261 cgatgcggat gacgaacagg gatacatcaa cgcggtgaag gcggaaatgg accaggggtt
    19321 tgaagaaatg accggtagta atctgcacaa tgccaaaaag cggttacgta agatattgcg
    19381 gctggtcaac aaacatattc gttacatggg gtccaaaccg gcagaggcgg aactgctgat
    19441 ttatttctgt gagcagttgc tggagtcggg gttgttacgg catcagagta cggtattgca
    19501 taatctgtac gccgcccagc tgaagaaaat agtgaaggtg accgtggggc tgcatgaaga
    19561 cctgcaatat gatttgaggc gccaggtaga gccgctgctg gaggtactga agtcctgatt
    19621 cgatgaccgc atatccaaat ggttttgatt tctccgggat aatgactatt ttttcctcag
    19681 cctttctttt tccggggctt tccactttat gaaaaacacg ctgaccggcc ttttcctcct
    19741 ctgtttaata gcttttttgc aatcgaatgc aagcgcacag ccgcctggcg ggaaaaagcg
    19801 gatgcctgtc ctgggcattg ccgcctcgat ggataatgac agtctggccg gcgcggccgg
    19861 tttctcctgc ctggaagaaa cagtaaagag aatgctggcg ccggccgtca gcgaggacgt
    19921 ctttgccgcc aatatagagc ggatcaacaa agcccgttgc cggatacaga cctgtaacgt
    19981 tttcatcccg ggatacctca aattaacagg acctgcggtc aacgaagcgt gggtattggg
    20041 gtacgtggac acggtcatgc aaagggctga aaaagcaggt atccggctga tcgtgctggg
    20101 aagcggggag gcgcgtaaaa ttccggaagg gtatgacccg gacatggcga aggggcagtt
    20161 tatccggctg gcccgtaaaa tggccgatat tgctaaaaaa cataactgcc tcattgccat
    20221 ggagaatttg aatgctaccg aaactaattt tgtaaacacg gtggcggaag cttgccaggt
    20281 agtgaccgct attgcgcatc ctcatttcag gctgacagcc gatatctatc atatgttaag
    20341 agaaaacgaa ccgccggcca atctcctgca ggcgaagggt atcctggtgc actgtcatat
    20401 cgcggagcgg gagaaacgtt ccgctccggg tacagagcgg caggatttcc ggccttacct
    20461 ggcagcgctg cgcagcatcg gatacaacgg gcggatcatg atggaatgcc ggtggaccga
    20521 tcctgcaaag gaatacgcgc cggccgtggc ttacctggaa gcgcaactca acgaagtata
    20581 tcatatctcc ggaaaaaaat aaaacacttg tacaatgaca accacaaaaa agacaaggcg
    20641 ggaatttctg caacagtccc tgatggcagg ggcgggacta acgatcacgg ctatgggaat
    20701 gccggccagc agttacgctc gtatactggg tgcgaatgac agggtgaacg tggggctggt
    20761 aggattttcc gaccgtgccc ggcaggcgtt gctgccttct ttcttcagcc ataacaaaga
    20821 actgaacttc gacctggttg cggtgtccga catctggaac cgtcgccggg aggagggcaa
    20881 agccttcctg gaagaaaaaa cagggcataa ggtgcgggcc tgtgtcaaca atgatgaact
    20941 gtaccggatc aaagacctgg acgccgtgtt cattgcgt
//
