LOCUS       NZ_FUWZ01000003        20963 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000003
VERSION     NZ_FUWZ01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 820632
            Orig. end                         :: 841595
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20963
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20963
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20963
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10963](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10963)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    1202..1217
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.32"
                     /tool="antismash"
     gene            complement(1287..4118)
                     /locus_tag="B5D63_RS22315"
                     /old_locus_tag="SAMN04488128_103720"
     CDS             complement(1287..4118)
                     /GO_component="GO:0031240 - external side of cell outer
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039936.4"
                     /locus_tag="B5D63_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103720"
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="WP_159456117.1"
                     /transl_table=11
                     /translation="MLRICLPILLLLSALQAHSRSSHPLPGQFRRPAYFIENKGQVTDQ
                     WRQGRTDIDFKLRASKELTIFIGSGKILYQWTAWGRVQGPSALMYRMEVKLAGARPGVL
                     PAATEQRPYREEYYLPGVASGMVAQAYSEVTYKDVYPHIDWVLRMTEDGHLKYDFVVRP
                     GGNPADIRLEYEGATRLSIGADGSLLAATPVDSIIEQAPYAYLQEGQRQVGCSFVLSGS
                     GTGLSFQMAPYKGTLVVDPMVLWGTYFGGVEYDQVSDLVYSKFDSCLYLTGATNSLSNI
                     ATSGSYQDTLAGGFDLSGSDAFISKMRPDGSLVWSTYYGGPDMDQGKKVALDSSGVYIA
                     GVTASLNGIATSGSYQPAKGGDSLAEKKDAFLVKFDTSGFRLWATYFGGSNHEGNTSIG
                     LAADGNGHVYLGGNTQSTDIAATPGCHQPASAGGQDGFIARFSSGGLLDWATYYGGSTA
                     DYIYDLATDAAGSLLVAGRTQSAGGIATAGAHQPAIGGGQDGFLAKFNPAGQLSWATYY
                     GGSGMDRVYCVKVGQNGNVFLGGTTNSSAAVATTGAHQSVFGGGSEDGIIAAFNPSGQL
                     LWATYYGGVNTESIWGIYCPGDSALLITGPTQSTDSIATQDGWQSLSGGSIDAFVAKFD
                     ADNGTRVWGSYLGGVDGDVALAITGDRDSKIFIAGSTSSATQVATPGSLQPAFAGGDAD
                     GFLVCVKDCRPPGSLAAIIGPAVICKGSDSSFSVAPGGSDSVIWIPAPGWVVTGSGDTV
                     SVAFGSGSGTLRAVPVNSCATGDTIALAITVNPAPDTPVITRSGNMLSVPSVYGSYQWL
                     RNDQAIAGATSSDYLVSTDGVYSVSVGNAEGCATVSAPININGTGIAALFASYGISIFP
                     NPVTDKLYIQTPTKVVIDICSVVGKRLLRRTLQQGLNVLGLDGLSSGIYLLTLTDNKGS
                     RLGSTRISLNRNL"
     gene            4290..6248
                     /locus_tag="B5D63_RS22320"
                     /old_locus_tag="SAMN04488128_103721"
     CDS             4290..6248
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="B5D63_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103721"
                     /product="ATP-binding protein"
                     /protein_id="WP_143313037.1"
                     /transl_table=11
                     /translation="MDTANRYLCCSCNQPPDQAKDHLKPLTYYCLLQMKTVISLLFLLL
                     LIQQPLAWSQPDIALQVARIDSMSDNDKAILSYQLMLRERSDLDAKTRIKILNHMGQRY
                     FGKGDNGALIRYLDQACKLAIKAGLNREVSALYNNLGIGYQSAGLYDSSLWYYQRSVAA
                     ATKYGTTISAAKPWLNMGLLYNRLKRYAPAIGAYNKAHMIAVAQKDTAMLAACYLNLGA
                     LYAGRYTPDSLGKAKLLLEEALQLTRRQGYDDIKHKANYSLGLMMENNGRPSEAVPYYE
                     AARNIPISEYDDCIPLLSLGHAYLKMGQLRKAQRALDSGLAKARRMVPAPDYLCDFYLY
                     YAQLLRAQKKPEQAAAFYEQYIDLSDSLRGAQTQARIDRLQREYESEKRDNELVKKELV
                     ISRQQAALQRKNMIVCAIIILGATAIALMAWYGRGRRRKQRLQQEKAVWVATFEGEERE
                     RQRISRELHDGIGGALSNARRWFATIGSEHPHLLRESDYGQALDLLDGTLADVRQTAHR
                     LMPQWLLKHGLVKAVELYCLQARRATSKNISFEYLGYVGEMGHRLHLMLYRCIQELLEN
                     AVRHSGASIILVQLSGHDDLLQVTVEDNGNGFDASAAEAGIGMAHITRGIEHIGGKVDI
                     RTAPGKGTSITFELKYA"
     gene            6267..6899
                     /locus_tag="B5D63_RS22325"
                     /old_locus_tag="SAMN04488128_103722"
     CDS             6267..6899
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="B5D63_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103722"
                     /product="response regulator transcription factor"
                     /protein_id="WP_078671049.1"
                     /transl_table=11
                     /translation="MTPINIIIVDDHPIVLSGLLKMLEGHSRVRLLATYRDAASLLAGM
                     GSHQPDVLLVDVQMPVMDGEALVKILTKQYPDVKLLVFSNFDQSYTVHRMFAAGAKGYL
                     LKGADKMTIIEAVETVHAGKNYLDATMREESLGELLGASRQAITLTLREQEVLDLLAKD
                     FTTKEIARTLFLSERTIDNHRSNLLLKLGARSVAGLVRKSMQMGLIN"
     gene            7063..7455
                     /locus_tag="B5D63_RS22330"
                     /old_locus_tag="SAMN04488128_103723"
     CDS             7063..7455
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103723"
                     /product="hypothetical protein"
                     /protein_id="WP_078671050.1"
                     /transl_table=11
                     /translation="MFAQSPSGYYSRLEKKMGVFIGHRKRLQMRLDFILRCWLEAGSAY
                     LDEYMEILRQVEVIERCIGVWIKPATELRDHLNLIVRTGMYPQDVSPILDDFEHIDIDW
                     CAIVGRAYEISLPPGSVFYRKGYVPA"
     gene            complement(7464..7736)
                     /locus_tag="B5D63_RS22335"
                     /old_locus_tag="SAMN04488128_103724"
     CDS             complement(7464..7736)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103724"
                     /product="hypothetical protein"
                     /protein_id="WP_078671051.1"
                     /transl_table=11
                     /translation="MAKDKRYKTLKTLLEGGNITGFDHLLEVVPLSRIGLDLGANYSTL
                     KKKFLAPETFTISDLYSIADLIETDPEPLIGLSKGAYLKKRKRRK"
     misc_feature    7765..7778
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    complement(7766..7779)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.77"
                     /tool="antismash"
     misc_feature    complement(7768..7781)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            8077..10029
                     /locus_tag="B5D63_RS22340"
                     /old_locus_tag="SAMN04488128_103725"
     CDS             8077..10029
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="B5D63_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103725"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_078671052.1"
                     /transl_table=11
                     /translation="MDYIDRKTKNDPPRNYKPQNIMHQLNTLLIAGTQGMLAEDKGRVI
                     VVNALCLLTVLLASVMGTAIFIASRDIGVLIAAWTEAAVFSGIIWLNSRRRHLLAAMLF
                     ILLHNVAVIYFGIWRQMTKEEELLTVFLCITSALIFKPIWHSSLAWLFCLFVIVIAYGV
                     TRRGIIAGEPLPVRDLYANLGLMAILLMTFFAILLSKYYDMRLNELLMQRSFRIRKYVH
                     QLEDYNKQLEGYSKQLESEVARRTDEVTRYAETVIHEMRNHAVSQQFASETVLGYLKYS
                     EDGSKFETIDDPSRLKAVIRYLSRKFGMVHRISRSIKETIDNTLDTHKIGDNRFFDFNM
                     TDVDLRSWSSHLTEVMQLVAAKDSVDISLEFDNGLPEVIRTDGHLLNCAVRNLLNNAID
                     FSPEHGNIRLAILQAPSMRELYIEVEDQGPGILREHINEIFKPYYTRRKGGTGLGLALV
                     SSAIDHLGGKIEVTSTIGKGSIFRIVIPLIVGEKQVETAEKTFTLNVERALRILITDDN
                     RVNRMFFSGMAKKLGCAAITANDANSCIEKVILERPDLLLLDIHMEGISGIEALRTIRT
                     MTDPELSRMPVIIATANTSEELPEELAALQPDAFLYKPFEAEDIVSSINMAMDKAKARM
                     QEYKAQSRQDCGTDR"
     gene            complement(10001..10963)
                     /locus_tag="B5D63_RS22345"
                     /old_locus_tag="SAMN04488128_103726"
     CDS             complement(10001..10963)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="B5D63_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103726"
                     /product="terpene synthase family protein"
                     /protein_id="WP_078671053.1"
                     /sec_met_domain="T1TS (E-value: 6.9e-58, bitscore: 192.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANESPVLKYPFADTISEHAPWLEQQTRTWLDELYPSLPPEIKEK
                     YRQTATGYLTARFFPFASAERLVPLAQSSLWGLAFDDVYEYCTPDTYAALSTRLTSIIQ
                     GESLPLQTENEFFHQMHVMAEGFRKFMPQFWMERFARSMKIYFEGMAAEAPFKAVLKIP
                     TLEQYVNIRWRSVDVLQMVDGLEVATEMPLPDQVRHHPQMEEIARLTCRIIAWANDFFS
                     VGKEQSRDVMNLVLVLQHQQGLSRPEAIAAAVRYHDEDVNTYLYRCQHLPEFGSYNDAV
                     QQFINYNNYMIAGHWRWYITDTKRYLPGGAPTDQFRSPA"
     gene            complement(10975..12090)
                     /locus_tag="B5D63_RS22350"
                     /old_locus_tag="SAMN04488128_103727"
     CDS             complement(10975..12090)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="B5D63_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103727"
                     /product="cytochrome P450"
                     /protein_id="WP_078671054.1"
                     /sec_met_domain="p450 (E-value: 1e-20, bitscore: 69.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTPPIVQNVYYDADFPLMSGGAGAWQVYRYQQVRELLFDYATYG
                     NGYMPDNGMLGSNLNQIDPPLHGQLRALISRFFSRGAIAGLEQDIENACRSLLAGCQDK
                     TVDVARDFAFPLTATVICEVLGISSGTEIMKVNNWAKAIVTAGYVEGGLAQAAVAQQEM
                     AGLFMQLLQSRAAEPRADLLSALALAEVGADALAPAAKIGTCMTILLAGYETTANLITS
                     AVHQLSVDHQLQATIRQSPAIIPNFLQEVLRLYPSIVSMYRIARKDVVLEGQLIKAGDI
                     INGWISTANRDPELFAEPDKLDLDRHNSSQALSFGYGIHHCIGAALARTQARIALEVLL
                     RESTRVMPGDGEPVRTPSLITPGFQTLPITL"
     gene            complement(12428..12718)
                     /locus_tag="B5D63_RS35805"
                     /old_locus_tag="SAMN04488128_103728"
     CDS             complement(12428..12718)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013540.5"
                     /locus_tag="B5D63_RS35805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103728"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_078671055.1"
                     /transl_table=11
                     /translation="MDYGKVFRRFRQYLRLSQRDFASLIGISQTSISLLESGKTAPTVE
                     TMARLAKMFNISVSTLYILALEVKCLTRKEREAIQYNYRLVQDILWFIACP"
     gene            complement(12696..13040)
                     /locus_tag="B5D63_RS35335"
                     /old_locus_tag="SAMN04488128_103729"
     CDS             complement(12696..13040)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS35335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103729"
                     /product="hypothetical protein"
                     /protein_id="WP_078671056.1"
                     /transl_table=11
                     /translation="MIINHQLIFSINESLPIFFLACFDSLSSLDKFSSIPNNGTKEHHF
                     CTCDLMCVRNGNSDDRQQLQRSYLASRLDLAYSIALLLDLPQYGNAEDRLLIKVSPPKK
                     ILPNGLWQGF"
     gene            complement(13054..13542)
                     /locus_tag="B5D63_RS22365"
                     /old_locus_tag="SAMN04488128_103730"
     CDS             complement(13054..13542)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS22365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103730"
                     /product="hypothetical protein"
                     /protein_id="WP_078671057.1"
                     /transl_table=11
                     /translation="MKKLVSRKYSIKLSTGRTVTVKAASLLSAHRKLSASVKGARCSDI
                     YQDDNTEPNLADGDPLPVPIIFRQYAIMATPARMLVDKATNKWEAYLRFLADGWNIGLG
                     DVYKRYTQPPHTNDAQFNSEHGLFASDSELLSCHIDLPSLMTGKGNKPMIVLTPKSTT"
     gene            complement(13675..14067)
                     /locus_tag="B5D63_RS22370"
                     /old_locus_tag="SAMN04488128_103731"
     CDS             complement(13675..14067)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS22370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103731"
                     /product="hypothetical protein"
                     /protein_id="WP_078671058.1"
                     /transl_table=11
                     /translation="MSKVPFTSDGVNFKQQQLYALSDADLIIEVKAIQNDFAAWMEQNF
                     YLSPLQKAYIVSAPDRAIWGAQIGAVVCTRGPIVIPTPPKDYGPAYRTKETRIKITGET
                     TFTPPVSGVPKIQGTLKATVEFTLVV"
     gene            14215..15096
                     /locus_tag="B5D63_RS22375"
                     /old_locus_tag="SAMN04488128_103732"
     CDS             14215..15096
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016296.5"
                     /locus_tag="B5D63_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103732"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_078671059.1"
                     /transl_table=11
                     /translation="MPEKPGQTGYHDGVIRFVLAFIAAHIVTEYGGQQPWLTRVFSIDY
                     YIEYGSTLAITILDIHIVYWVTLQLDRKFSWLDHPVFRGLLQVAFGLLLPTLITFLLAA
                     GYFRLYGMDILDTNYHLYALPFISSLIALFNVYYLVRYLLREREHYWQMVLQSDRDNSM
                     VAPATMPAPEPGMPLLEKSVFIVHTPTRSFPVATGDIAYFYREEGQVYLRAFAGNKHIL
                     SQSLEQIEEQLNKDDFFRVARHMIASRAAVRGYEKDTYGKLSLKLEPTPEYKRSITISQ
                     NKAGKFREWLDR"
     gene            15479..16312
                     /locus_tag="B5D63_RS22380"
                     /old_locus_tag="SAMN04488128_103733"
     CDS             15479..16312
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020914.5"
                     /locus_tag="B5D63_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103733"
                     /product="RteC domain-containing protein"
                     /protein_id="WP_078671060.1"
                     /transl_table=11
                     /translation="MISFAQELERRMLDQLEEITRQAETDLQQAERSYLLIRGCLRELT
                     DFGRDYVFKDRKEELTFYKEVKPKFVREWFFYCRLFSLEASMPVGSSEQQACWMKRQLE
                     ELNQYLTDNQFLYLYSRSGQTYMDEQLFVAEPADALVLMYARDSEPDGGNTFSYLLGKI
                     QAAEDLAAYLLRRIALTSQGEPAAELDKQEVHWDGSLAQLYEIGYGLFTAGLVRGTVKS
                     VIERLGYAFAVKPGNYYRYMLNMRIRKKSPTQCLDLMTSSLLEYMRQADLDPKYK"
     gene            16336..17097
                     /locus_tag="B5D63_RS22385"
                     /old_locus_tag="SAMN04488128_103734"
     CDS             16336..17097
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020914.5"
                     /locus_tag="B5D63_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103734"
                     /product="RteC domain-containing protein"
                     /protein_id="WP_078671061.1"
                     /transl_table=11
                     /translation="MLAEMNALHYQLKSDLQHMEATAISPLAQADACFRLTSLYFAQLK
                     HMVDAHVFSPQEQITLYKYITPGFLEEVIFYLSLIDLESRDGDVGQLQRYYHDELESVK
                     SFLERQDFLRQYMALGKEYLDDILFSHRPPDAEVFPESLGFAGTEYFNPHSYLVARIAA
                     SLRLHRFLEQKLAGGTPAADLMQSPELPLPGGLPDVPPPQLQMVMDDIRQKFSWLKTKV
                     VPGSGNQSRLLLQARIKYNLRLFNEHPKTNS"
     gene            complement(17115..17552)
                     /locus_tag="B5D63_RS22390"
                     /old_locus_tag="SAMN04488128_103735"
     CDS             complement(17115..17552)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103735"
                     /product="hypothetical protein"
                     /protein_id="WP_143313038.1"
                     /transl_table=11
                     /translation="MRYDKELLTDLLKALPAWGLVPEKFLEFILVAVEMFAHRTGGELL
                     TVETLHEAQRELAAAFLFAFKLELFPYTDFDDLRQKAGPFIDIDRTISRVQDWKQQAAA
                     VWDLCEASVVTPNQETVMEDALEDLRARVVIKKLESYLTFS"
     gene            17753..18580
                     /locus_tag="B5D63_RS22395"
                     /old_locus_tag="SAMN04488128_103736"
     CDS             17753..18580
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020914.5"
                     /locus_tag="B5D63_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103736"
                     /product="RteC domain-containing protein"
                     /protein_id="WP_078671063.1"
                     /transl_table=11
                     /translation="MKPLSSYQQIMASRLHASEKAGQTVLQRCGSAIAIVEQVLQELNP
                     VLSDTQFLNAGEEINFFKLQLPAIHAQLIYHQSVSWLESRKPVGDYAIHRHYYSSELDR
                     IRRYSEDHRDFYQYHRTGATYWDEHLFQRGHELLPQLRHEYSFAMDRRINTQGTMLVAT
                     MQAYDLLREFIEQQTAQVDCRPAAVGSTDHKLLKWTDSKTALAEMIYAFWFKGSFNNGA
                     AELKEIQAYVEQIFDIRIGNIYQIKQEMYARENISAYQDLLHKRFKEGMEQSL"
     gene            18727..19050
                     /locus_tag="B5D63_RS22400"
                     /old_locus_tag="SAMN04488128_103737"
     CDS             18727..19050
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013632691.1"
                     /locus_tag="B5D63_RS22400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103737"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_078671064.1"
                     /transl_table=11
                     /translation="MNIDRMEFMAWMERIMNRLDILGEQISDARKQNGSIDGEELLDNQ
                     DILQMLKISNRSLQRYRSTGRLPYYTISGKLYYKLSDVHQFVRESVNDRIMKSTLVADK
                     YRR"
     misc_feature    complement(19118..19127)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     gene            19127..20527
                     /locus_tag="B5D63_RS22405"
                     /old_locus_tag="SAMN04488128_103738"
     CDS             19127..20527
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013632655.1"
                     /locus_tag="B5D63_RS22405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103738"
                     /product="DUF3945 domain-containing protein"
                     /protein_id="WP_078671065.1"
                     /transl_table=11
                     /translation="MSEQNPEMPQASDQLSDILLVFDKEKMKIQAVKDIDKNGELRTVP
                     PTKKNQNQFMRVDRHGDIFSNFFANFMSQLKNPTRFSFFKVPVHEAIKTAKELQEHVNK
                     PSEQGQELSKKLEVKNEPKPANNPDMEVTQTTTPPSAEPQKVPEQRTARYQSEQVDWDS
                     LAKFGLSKESLEKAGVVDDLLKGYKTNKLLPVTINTDKAVFRGEARLSLRTNDEGTVMA
                     QLNGVRQEPELDLPFFGHKFTDEDKTNLRSTGNMGRVVDLTNMKTGEKIPSYISIDRLT
                     NEVVAYRTSTIKIPDEIKGVKLDDHQKQSLAEGKPTYIEGMVSAKNTPFNATLQVNADK
                     GYIEFIFNRSMNAQQTLDTQQRQDAPRLFRGYELNDQQYKRYNAGKSVAVNGLVSKEGK
                     PYEGFIKFDFDTRKAIFSYTDPDRIYKQATQTAETPKQDTGKDQINTNQKQDQKKPKSP
                     KKSASPKM"
ORIGIN
        1 tgttccaagc gtaccggtgt aggccggaac aacaagcgtg ttaagctccg gcaaacaagc
       61 cgggcctgcc aggtccggct gatgcagcac atgaaagccc ggccccggat tgtatcctgc
      121 cgggacgagt gccagcggca agcaagtctg gctaccattg tcgatgtaaa cctttcggtc
      181 gggaccggcc tttatttccc ccaacgggtt ctggacggtg aggatgcaaa gcccgctgat
      241 atcctggagc aacgatggct ggttggtaat gatgaggttc ttagaagcaa tgatagcggg
      301 aaggccggat tgatcgacat cgtactggaa caaacgccct ggcatcagca acccgtttat
      361 ccaatagttc tggctggcat acagctttga gttgtcaggg gaaaagcaaa tgtcctggaa
      421 ccgggtatgg ttaagggccg tggcgggagc cagcgggtct ccattgccgg tcgtttcaag
      481 tactaatgtg ttggtaattt tcccactgca gggctcaaaa ggaaacagct ctatgccctg
      541 ccagccgcaa caggctagca tactgccatc cggcgccgct ttcaggaaac cgaagtcatc
      601 atagttgtaa tgaaagggcg cagaaaaggt gcccgcttcc gagatcaccg gttcagggtg
      661 cagaccggcg ccatcaatac cgaagctgta gaactggttg gcggtccggg aacgcaccac
      721 cagccagatg ccccggcaac ctttaacggc cgtcattttt ttggcgacga tggtaccata
      781 ggcagagagc acaacatctt tttggccggc aacgatgccg cctgcgccgc cattaaggcc
      841 catgtccagc aggctgtata gcaagccctt gccataggaa tagaaaatat aatactggtc
      901 ggcgttacct ggatgcggta ccactaccgg cttgcagctt tcagtcagcg ccccggtgcg
      961 tagctctgtg cccacaatag gcgttccatt gaccctgaaa atacaaggct ccggatatcc
     1021 gggtacatta acccgaagct ggacaataaa gcgcagctga ccattaggct tgcagactgc
     1081 cgccgaccac caggtaccat tgccaggcaa gggatagctg gtgatcgttg gcgaagtacc
     1141 ggaaaaatcg atggcggtgt tggcaactgt ttctatcgtt gaaaagaagc agatattatt
     1201 ttcgccctgt gcgaacaagc ccgcaggctg caagatatag aacatacaga gacaggcgat
     1261 caaaaaatca tacaggcgtt tagagatcat aggttgcggt ttaaagagat acgtgtagag
     1321 ccgagacggc tgcctttatt atccgttagg gtgagcagat aaatgccact gctcagacca
     1381 tcgaggccca gcacattcag cccctgctgc aaagtgcgcc gtaaaagccg tttgccgacg
     1441 acgctacaga tgtcaatgac taccttggta ggcgtttgga tatagagctt atccgtgaca
     1501 ggattgggga agatgctgat cccataagag gcgaacaacg ctgcaatacc agtaccattg
     1561 atgtttatag gtgccgaaac tgtagcacaa ccttcggcgt tgccgacgga aaccgagtag
     1621 accccatcgg tgctgaccag gtagtcggag cttgtagcgc cggctatggc ctgatcgtta
     1681 cgcagccatt ggtagctgcc gtaaacggaa ggaaccgaaa gcatgtttcc gctgcgggtg
     1741 ataaccggcg tgtccggtgc cggattaacc gtgatcgcta aagcaatggt atcacctgta
     1801 gcgcagctgt tgacaggtac cgcacggagc gttccgctgc cgctgccgaa agcaaccgaa
     1861 acggtatctc cgctgccggt tacgacccat cctggggccg gtatccagat aacggagtcg
     1921 cttccgccag gcgctacgga aaaagaactg tcggagcctt tacatatgac agcgggccct
     1981 atgatggcgg caaggctgcc tggaggccgg caatccttga cgcagaccag gaaaccatcc
     2041 gcatcccctc cggcaaaagc aggttgaaga ctgccgggtg tggccacctg cgttgcgctg
     2101 gatgtgctgc ctgcgataaa tatttttgaa tcccggtccc cggtaatggc tagcgcaaca
     2161 tcgccatcca ctcccccaag atagctcccc cataccctgg ttccgttatc ggcatcgaac
     2221 ttagctacaa aggcgtctat gctgccaccg gataaggatt gccagccgtc ctgtgtcgcg
     2281 atgctatcgg tactctgcgt agggccggtg atcagcaagg cgctgtcacc gggacagtag
     2341 atgccccata tgctctcggt gttaactcct ccatagtagg tggcccataa cagttgacct
     2401 gaaggattaa aagcagcgat gatgccatct tcgctaccgc ccccgaaaac ggattgatgc
     2461 gctccggtcg tggcaaccgc agcagaagag tttgtcgttc caccaaggaa gacattgccg
     2521 ttttggccga ccttgacgca gtagaccctg tccatcccgc ttcctccata gtaggtggcc
     2581 cagctcagct gcccggccgg gttgaactta gctaaaaaac cgtcctggcc gccgcctatt
     2641 gccggttgat gggcgccggc cgttgcaatt ccaccagcgc tttgcgtcct gcccgccacc
     2701 agaaggctgc cggccgcatc ggtagccaga tcgtaaatgt aatctgccgt gctgccgcca
     2761 taataggttg cccagtccag cagaccgccg ctgctaaacc tcgcgataaa cccatcctgc
     2821 cccccggcag atgctggctg gtggcatccg ggtgtggccg caatgtcggt gctttgggta
     2881 ttaccgccca ggtacacatg gccgttgcca tctgctgcca gtccgatgga agtattgccc
     2941 tcatgattgc tgccgccaaa gtaggtggcc cataaccgga agccggaagt gtcgaatttg
     3001 accaggaaag catccttttt ttccgccagg ctgtccccgc ctttggcagg ctggtagctg
     3061 cctgaagtcg cgatcccatt aaggctggcc gtaaccccgg ctatgtaaac gccagaactg
     3121 tccagcgcta cctttttacc ttggtccata tccgggccac cgtaataggt agaccaaacg
     3181 agcgacccgt ccggcctcat cttcgagatg aaggcatcgg agccggaaag atcgaagcca
     3241 cctgcaagcg tatcctggta gctaccggag gtggctatgt tactcaggct gttggttgcc
     3301 cccgtgagat aaaggcagga atcgaatttg ctgtaaacga ggtcgctgac ctggtcatac
     3361 tcgacgccgc caaaataggt gccccacagc accatcgggt cgacaaccag ggttcccttg
     3421 tagggggcca tttggaagct aagtccggtg ccgctaccgg acagaacaaa agaacagcca
     3481 acctgccgct gcccttcctg caggtaagcg taaggcgcct gctcgatgat ggaatccact
     3541 ggtgttgcgg ccagcaggct tccatcggct ccaatgctta gccttgtggc gccttcatac
     3601 tccaggcgta tatcggcagg gttccccccg ggccttacca caaaatcata tttaaggtgg
     3661 ccgtcttcgg tcatgcgcag cacccaatcg atatgaggat agacatcctt ataggtcacc
     3721 tcgctgtagg cttgggccac catacctgag gcgacaccgg gcaggtaata ctcttccctg
     3781 tagggccgct gctcggtagc tgcaggcaga acgcctggcc gggccccggc aagcttgact
     3841 tccatgcggt acattaaggc agaggggccc tgcacgcggc cccaggctgt ccattgatag
     3901 agtatcttac cgctgccgat aaagatcgtg agctctttgg aagcgcgtag cttaaaatcg
     3961 atatctgtcc ggccctggcg ccactggtcg gtgacttgcc ctttgttctc tatgaagtag
     4021 gcaggcctgc ggaactgacc gggtaaagga tgactgctgc ggctatgggc ctgcagcgcc
     4081 gacagtagca acagtatagg taaacagatg cggagcataa caaacaaatt aagaggtgaa
     4141 acataaaggt tagcaaagct aggctgcagt atttgtagcg ggcaggtggg atttgccgtt
     4201 tttaatttgc aggaatccac aatttttacc tgcgggattc cgcatttttt ttgttgttgc
     4261 ccggaaagac cggccatgcc cgtatatttg tggacactgc aaatcgttac ctctgctgca
     4321 gctgcaacca accgccggac caggccaaag accacctgaa acccttaacc tactattgcc
     4381 tactacaaat gaaaaccgtc atctcgttgc ttttcctgct attactgata cagcagccgc
     4441 tggcatggtc gcagcctgac atagcgctac aggttgcccg gatcgattcg atgagcgata
     4501 atgacaaagc aattctttcc tatcagctaa tgttgcggga aaggtctgat ttggatgcca
     4561 aaacccgcat aaagatcctt aaccacatgg ggcagcggta ttttggtaaa ggagataatg
     4621 gcgccttaat acgttacctg gaccaagcgt gtaagctggc aataaaggcc ggcttgaacc
     4681 gggaagtgtc cgccttatac aacaacctgg gtatcggcta ccagagtgcc ggactttatg
     4741 atagttcatt gtggtattat caacggtccg tagcggctgc gaccaaatat ggcaccacga
     4801 tttctgctgc aaagccctgg ctcaatatgg gcctgctata caacaggctt aaacgttatg
     4861 ctcctgccat cggggcctac aacaaggccc acatgatagc tgtagcgcaa aaggatactg
     4921 ctatgcttgc ggcctgctac ctgaacctgg gagcgctcta tgccggcagg tacacgccgg
     4981 acagtcttgg caaagcaaag ctgttgcttg aagaagccct tcagcttacc cgcaggcaag
     5041 gatatgatga tattaagcat aaggccaatt actcgctggg cctgatgatg gaaaacaacg
     5101 ggcgcccttc cgaagcggtg ccgtattatg aagcggcaag gaatatcccg atcagcgagt
     5161 atgacgattg tattccgctg ctcagcctcg gccatgctta cctgaaaatg ggccagctcc
     5221 gaaaggcaca gcgggcgctg gacagcggtc ttgccaaagc aagacggatg gtgccggcgc
     5281 cggattacct ctgcgacttt tacctatact atgcccagct gctccgggcg caaaagaagc
     5341 cggagcaggc agcagccttc tatgagcaat atatcgatct ttccgacagt ctgcggggag
     5401 cgcaaacaca agccaggatc gatcggctgc aacgggagta tgaaagcgaa aaacgggata
     5461 acgagctggt aaaaaaggaa ctggtgatct ctcgccagca ggccgctttg caacgaaaga
     5521 acatgatcgt ctgtgcgatc attatcttag gtgctacagc tatagcgctg atggcatggt
     5581 atgggcgggg gcgccgccga aaacagcgcc tgcaacagga aaaagcagta tgggtcgcca
     5641 ccttcgaggg cgaagaaaga gagcggcaaa ggatctcccg cgaactgcac gacggcatag
     5701 gcggtgcctt gtccaatgcc cgccgttggt tcgccacaat tggcagcgaa catccacacc
     5761 tactgcggga aagtgattac ggccaggcgc tggacctgct ggacggcacg ctggcggacg
     5821 tgcggcaaac ggcgcaccgg ctcatgcccc agtggctgct caagcatggc ctggtcaaag
     5881 cagtagagtt atactgcctg caggcgcgcc gggctacctc taagaatata tcctttgaat
     5941 acctgggcta tgttggggag atgggccaca ggcttcacct gatgctttat cgctgtatac
     6001 aggagctgtt ggaaaatgcg gtccggcact ccggcgctag cataattctt gtgcagctca
     6061 gcggccacga cgatctattg caggtcactg tcgaggataa tggtaacggc tttgacgctt
     6121 cggcagctga ggccggtatc ggtatggccc atatcacaag gggcatagag cacataggcg
     6181 ggaaggtgga tatccgtact gcccctggta aaggcaccag catcaccttt gaacttaaat
     6241 acgcataacc tttcataatc attaccatga ccccaattaa tattatcatt gtcgacgatc
     6301 atcccatagt gctgagcggc ttgctgaaaa tgctggaagg ccatagcagg gtcaggttgc
     6361 tggctaccta ccgggacgct gcttcactgc ttgcaggaat gggaagccat cagccggatg
     6421 tgctgcttgt agatgtgcag atgccggtta tggacggtga agccctagtg aagatcctca
     6481 cgaagcagta cccggatgtg aaactactgg tcttttccaa tttcgaccaa tcttataccg
     6541 ttcaccgaat gttcgctgcc ggggctaagg gatatttgct caaaggggca gacaagatga
     6601 ccattatcga ggccgttgaa actgtccatg ccggaaagaa ctacctcgat gcgaccatga
     6661 gagaagagtc ccttggtgaa ctgctgggag ccagcaggca agctattacc ttaactttgc
     6721 gcgaacaaga ggtgcttgat ctgctggcaa aagactttac caccaaagag atagcccgta
     6781 ccctgttcct gagcgaacgc acgatcgaca atcatcgcag taatttgctg ctgaagctgg
     6841 gggccaggag cgtagccggt ttggtaagga aaagcatgca aatgggactt attaactaat
     6901 catgttcgtt aagcattttg cctttagatg aaattgacat attaattcag gcgacggctt
     6961 tacctttaag gaagatggcc agagatcgag tttacttagc agatcgtcag ctgagaaaga
     7021 tcgaacattt gtattactaa acccttacca aaatcgcccg ccatgtttgc tcagtcaccc
     7081 agcggctatt acagccggct agaaaagaaa atgggagtgt ttatcggtca cagaaaaagg
     7141 ttgcaaatgc gccttgactt cattttgcga tgctggctgg aagccggttc cgcttacctg
     7201 gacgagtata tggagatttt acgtcaggtc gaggtaattg aacgctgcat cggtgtatgg
     7261 ataaagccgg ccacagaatt gcgcgatcac ctcaacctga ttgtcaggac cggcatgtat
     7321 ccacaggacg tcagccctat actggacgat tttgagcata ttgatattga ttggtgcgcc
     7381 attgttggac gggcctacga gataagcttg ccgccaggaa gcgtttttta cagaaagggc
     7441 tatgtccctg catgacccaa caactattta cgcctttttc gctttttaag gtacgcccct
     7501 ttcgaaaggc cgatgagtgg ctccggatct gtctcaatga gatcggcgat gctgtacaga
     7561 tctgaaatcg tgaaggtctc cggcgcgagg aatttctttt ttaatgtcga gtaatttgca
     7621 cccaggtcca gcccgatacg ggaaagcggc accacttcca gcaggtggtc aaagccggta
     7681 atattgccgc cctccagcaa tgtttttaaa gttttgtatc ttttatcctt cgccattcgg
     7741 ccttaaaaat aaggcgtcag gataattttg tattaaaaaa cgacagatgt gtttttattt
     7801 actacaaatc tgttgtaaaa aaaatcaaaa ttgtattttt ttgtttctcg ggattgttct
     7861 acattagtgt aaagcgtgcg ccactgctgt gtatcgcttg agaaggtaag ttccccacca
     7921 ggattaatta agaccactcc gcgcgtttca acaccatcag ccccggtcag ttttgtattc
     7981 caaagagatc tgccactggc ttcctgtatc tatgcattgc tggattaaat gttaatacgc
     8041 ctggatttgg aagccattca caactgccag tgacctatgg attatattga tcgaaaaact
     8101 aaaaacgacc caccgcgtaa ctataaacct caaaatatca tgcaccaatt gaatactttg
     8161 ttaatagccg gtacgcaagg aatgcttgcc gaagataaag gccgggtaat tgttgttaac
     8221 gcactttgtt tgctcactgt attgttggct tcggtgatgg ggacggcaat atttatcgca
     8281 tccagggata tcggcgtgct gattgcggcc tggacggaag ccgcagtttt ctccgggatc
     8341 atctggctca atagccggcg cagacacctt ttggcggcca tgctcttcat tctccttcac
     8401 aatgtagccg ttatttactt cggcatctgg cggcaaatga caaaggaaga agaattgttg
     8461 acggttttcc tgtgtattac ctcagcgctt atatttaagc ccatatggca ttcctctttg
     8521 gcatggttgt tttgcctgtt cgtaattgtg attgcctacg gcgttacccg ccgtgggatc
     8581 attgccggtg aacccttgcc tgtccgtgac ctgtacgcaa atcttggact aatggccatt
     8641 ctgctgatga ctttttttgc catcctttta tctaaatatt acgacatgag gcttaacgaa
     8701 ctactcatgc aacgaagttt caggatacgt aagtacgtcc atcaattgga agattataac
     8761 aaacagcttg aaggctatag caagcaatta gaaagcgagg tagcgcgacg aaccgatgag
     8821 gtgacgcgtt atgcggagac ggtaatacac gagatgcgta accatgcagt gtcgcagcaa
     8881 ttcgcctcag agaccgtgtt aggctatctg aaatatagtg aggacggcag caaatttgag
     8941 accattgacg acccctccag gctaaaagca gtcatccgat acctgtccag aaaatttggg
     9001 atggtccacc ggatcagcag aagcattaag gaaacgatcg ataatacgct ggatacgcac
     9061 aagatcggcg ataacaggtt ttttgatttc aatatgacgg atgtggatct ccgctcctgg
     9121 agttcgcacc ttacagaggt aatgcaatta gtggcagcca aagactcagt agacatatct
     9181 ttggaattcg ataacggcct gcccgaggtt atccggaccg acggccattt gcttaactgt
     9241 gccgtcagga accttttaaa caacgctatc gattttagtc ccgaacatgg aaatatccga
     9301 ctagccatat tacaggcccc ttcaatgcga gagctataca tcgaggtcga ggaccaggga
     9361 ccggggattc tacgagagca tatcaatgaa atttttaagc catattatac gagaagaaaa
     9421 ggaggtaccg gcctggggct ggcgctggtc agctctgcca ttgatcatct tggaggaaag
     9481 attgaagtga cctccacaat cggtaaagga agtatcttcc gtatcgttat cccgctgatc
     9541 gttggagaaa aacaagttga aacagctgaa aagaccttta cacttaatgt tgaaagggcc
     9601 ttgcgcattc tgattaccga cgataatcgc gtcaatagaa tgttttttag cggtatggcc
     9661 aaaaagcttg ggtgtgcagc cattacggca aacgacgcca acagctgcat tgagaaggtt
     9721 atcctggaaa ggccggatct tttgttgctg gatattcaca tggaagggat cagcggcatt
     9781 gaagctttgc gaacgataag gacaatgacc gatccggagt tgagcaggat gcctgtcatt
     9841 atagctactg caaacacgtc ggaggagcta ccggaggaat tggctgctct tcaaccagac
     9901 gcattcctct ataaaccttt tgaagcggaa gatattgtaa gtagtatcaa catggctatg
     9961 gacaaggcta aagcccggat gcaggaatat aaggctcagt ctaggcagga ctgcggaact
    10021 gatcggtagg cgcgcctcct ggtaaatatc ttttggtatc ggtgatgtac caacgccagt
    10081 gcccagcgat catgtagtta ttgtagttga taaattgctg caccgcatcg ttataggaac
    10141 cgaattccgg caggtgttgg caacgataca gataagtgtt cacatcctca tcgtggtaac
    10201 ggactgcagc tgcaatagct tctggtctac taagcccctg ttgatgctgc agtaccagga
    10261 caaggttcat tacatccctg ctctgctcct tccctacgga gaagaaatcg ttggcccagg
    10321 caatgatcct gcaggtcagc cgggcaattt cttccatttg gggatgatgc ctgacctgat
    10381 cgggtaaagg catttcggta gcaacttcaa ggccatctac catctgcagc acatcgacgc
    10441 ttcgccaacg gatgtttacg tactgctcca gtgtcggtat tttcaagaca gctttaaatg
    10501 gcgcttcggc tgccataccc tcaaaataga tcttcatgct ccgggcgaaa cgttccatcc
    10561 agaattgcgg catgaatttc cgaaagcctt ctgccatgac atgcatttga tggaaaaact
    10621 cgttttcggt ttgcagcggc agggattccc cctggataat actggtcaat ctcgtgctca
    10681 atgctgcgta ggtatcgggg gtgcaatatt cataaacatc gtcaaaggca aggccccaaa
    10741 gagagctttg ggcaagcggc accagccgct ccgctgaggc gaaggggaaa aaccgagccg
    10801 ttaaataacc cgtggccgtt tgccggtatt tttccttgat ttcgggaggc aggcttggat
    10861 ataattcatc tagccaggtg cgggtctgct gttccagcca gggtgcatgt tcactgatag
    10921 tatccgcaaa gggatacttt agaaccgggg attcgtttgc catgtaggga aagtttataa
    10981 agtgatcggc aatgtttgaa atccaggggt aatcaggctc ggtgttctca ccggctctcc
    11041 gtcacctggc atgaccctcg tgctttcacg gagtaatact tccagtgcta tccgggcctg
    11101 tgtcctggca agcgcggcgc caatgcagtg atggatacca tagccaaagc ttagtgcctg
    11161 gctgctgttg tggcggtcga ggtcaagctt gtccggctcc gcaaagagct ccgggtcccg
    11221 gttggcggta ctgatccagc cattaataat gtctccggcc ttgatcagct gtccttcgag
    11281 caccacatct tttcttgcga tacggtacat gctgacaatg ctggggtaaa gccgcagcac
    11341 ctcctgtaaa aagttcggaa tgattgccgg tgactgccgt atggtggctt ggagctggtg
    11401 gtctactgat agctggtgaa ctgcgctcgt gatcaggttg gcggtggttt catagcctgc
    11461 aagcagaatg gtcatacagg tcccgatctt cgcagccggc gccagcgcat ctgctccgac
    11521 ttcggctaaa gccagagccg aaagcaggtc tgctctaggc tccgccgccc tggactggag
    11581 cagttgcata aatagtccag ccatttcctg ttgggcaacg gcagcttgcg cgaggccccc
    11641 ctccacatag ccagcagtga cgattgcctt ggcccagttg ttaactttca ttatctccgt
    11701 ccccgacgag atccccagta cctcacaaat gaccgttgcc gtaagcggaa aagcaaagtc
    11761 acgcgcgaca tctaccgttt tatcctggca accggccagc agtgatcggc aggcgttttc
    11821 aatgtcctgc tccaggccgg caatcgcacc acggctgaag aatcgcgaga tcagtgcacg
    11881 cagctgtcca tgcaagggag gatcgatttg attgaggttg ctgcccagca taccgttatc
    11941 gggcatataa ccgttcccgt aggtagcata atcaaatagg agctccctta cctgctggta
    12001 acggtatacc tgccaggcgc cggccccacc ggacattaaa ggaaagtcgg catcataata
    12061 cacgttctga acaataggag gtgtaggcat gacagttagt tattatagac aagataatcg
    12121 gggtaacggc aatcaggccg cagtggaaat ttgtaaggag gttaattgag cgaaaaagaa
    12181 ggttttggga tctcgaattt tggtttaaac ttaaaagcgt ccggcagctc tagctgccgg
    12241 agcgctatta gcccgtccat atggctgttt ccgtccattg tggcccaatg cctcagttga
    12301 aaacgctatt taagctgctt gacgcatgga catcgtctat ggtttcatcc ataaccataa
    12361 acgaaatgca ggcgagaaag tactattact ttagcatagt tttttgatta cctactgtct
    12421 tatttattta ggggcaagcg ataaaccata ggatatcttg gacaagccga taattatact
    12481 ggatcgcttc gcgttcttta cgcgtgagac atttaacttc aagagccagt atgtacaacg
    12541 tgctcaccga gatattaaac atttttgcga gtctggccat cgtttcgaca gtaggcgcgg
    12601 tcttaccgga ctccagcagt gagatgctgg tttggctgat accgatcaat gacgcgaagt
    12661 cccgctggct cagacgcaga tactgtcgaa accgtctaaa aaccttgcca tagtccattg
    12721 ggtaatattt tttttggagg ggacactttg atcagaagcc tatcctcagc atttccatac
    12781 tgcggcagat caagcaataa agcgatgctg taggctagat ccagccggct cgcgaggtag
    12841 cttcgctgca gctgctgccg atcatcgctg ttgccgttac ggacacacat cagatcgcag
    12901 gtacaaaaat gatgctcttt ggtgccgttg ttggggatac tactaaactt atcgagactg
    12961 gaaagggaat caaaacatgc taagaagaat ataggaagcg attcgtttat agaaaaaata
    13021 agctggtggt taattatcat ggattgattt tttttaggta gtagattttg gagtcaatac
    13081 gatcataggc ttatttccct taccggtcat cagggaaggc aaatcgatgt ggcatgataa
    13141 tagttctgaa tcactcgcaa ataagccgtg ctcactattg aactgcgcat cattcgtgtg
    13201 gggaggttga gtgtaccttt tatacacatc accgagtcct atgttccagc catcagccag
    13261 gaacctcagg tatgcttccc atttgtttgt ggccttatcc accaacatac gtgcaggagt
    13321 agccataata gcatattgac ggaaaattat cggtacaggg agcggatcac catcggcaag
    13381 atttggctct gtattgtcgt cctggtaaat gtcgctgcat cttgctccct tgacacttgc
    13441 tgaaagtttg cgatgtgcag atagcaagct tgctgctttt accgtaacgg tcctaccggt
    13501 ggatagtttg atggaatatt tgcgactaac tagttttttc atgcgggcat gtcatttctt
    13561 ttataacggg ttacggtcaa aaaagtacta ttcattcgaa tctaatcgga tcaatacagt
    13621 ttcctgttac aaggaaggcg gagggtcgtc ccccttccgc cttgtccctt tctgtcagac
    13681 gacaagggta aattctaccg tagctttaag cgtaccttga atttttggca cacctgaaac
    13741 aggaggtgta aacgtcgttt cgccagttat ttttattctg gtttctttgg tcctgtaggc
    13801 agggccatag tctttgggtg gagttggtat aacgatcggg ccgcgtgtac aaaccacggc
    13861 cccgatctga gctccccaaa tagcccggtc tggggctgat acgatgtagg ccttttgcaa
    13921 cggactcagg taaaaattct gctccatcca ggcggcaaaa tcgttttgta tggctttaac
    13981 ttcgattatt agatcagcat cgctaagggc atagagttgc tgttgcttga agtttacgcc
    14041 gtcggaagtg aagggtacct tagacatcag taagagattt atagattaat ggtataaaaa
    14101 agttgaggtg acggtccgga ataatcctta tactatctac agtgtataat ttaaataaat
    14161 atttttatat ttataagtac ttgtgttctt aaaatagcct aaaaatattt tgctatgccg
    14221 gaaaaacccg gacagacagg ataccatgat ggcgttatcc ggtttgtcct cgcttttatc
    14281 gctgcccata ttgttaccga gtatggaggg cagcagccct ggcttaccag ggtcttttct
    14341 atcgactact atatcgaata cggaagtaca ctggccatca ccatccttga cattcatatc
    14401 gtgtattggg taacgttaca gctggaccgg aaattctcct ggctggacca tccggttttt
    14461 cgcggcctgc ttcaggtggc attcggactg ctgttgccga cactgatcac ttttcttttg
    14521 gcggctggat atttccggct ctatgggatg gatatcctgg ataccaacta ccacttgtat
    14581 gccttacctt ttatcagcag cctgattgct ctattcaatg tttactacct ggtccgctat
    14641 cttctccgcg agcgggaaca ctattggcag atggtgctcc aaagcgacag ggataactct
    14701 atggtagcgc cagctaccat gcctgcgccg gaaccgggga tgccgctcct ggaaaagtcg
    14761 gtattcattg tccatacacc cacccgtagt tttcccgttg caacgggcga cattgcctat
    14821 ttctaccgtg aggaaggaca ggtgtacctc cgggcgtttg ctgggaacaa gcatatcctt
    14881 tcccaaagcc tggagcagat cgaagagcaa ctaaataaag atgatttttt ccgggtggcg
    14941 aggcatatga tcgcgagccg ggctgccgtg cgcggatacg aaaaagatac ctacggtaag
    15001 ctatcgctga agctcgaacc gacgccggaa tataaaaggt ctataacgat cagccaaaac
    15061 aaggccggca agttcaggga gtggctcgac cgttgagaaa gtaaagcagg cttccgacta
    15121 tggattgaca atcatatttt agtagttcac gaattatttc aagcgcccgc ttctctactt
    15181 ttccctgcca gtagctgatt ttcgtttttt tatacaactc ggtttgcgat atgcctcttt
    15241 aaacgaagcc tgtcccggca attatatatg cgtatggcac gatcaacgaa aaaattagtt
    15301 taagtttgtt tgagcccaat agtttcagaa ccatcattta gtaaagtaat tcagtaattc
    15361 accggcgaca tttgcgatat cagcaaattt ggccggctga agcgcgcttg ttgcgccttt
    15421 accgaattat tttgctaccg taaacgacga cctatcgaaa cctgaaacca attaatagat
    15481 gatatctttt gcgcaagagc tggaaagaag gatgctggac caattggaag aaataacacg
    15541 gcaggctgaa acagacctgc aacaagccga gcgttcctat ctacttatta gaggttgcct
    15601 gagggaactg accgactttg gccgggacta cgttttcaag gatcggaaag aagagctgac
    15661 gttctacaaa gaggtcaagc cgaagtttgt acgggaatgg tttttttatt gcagactctt
    15721 ctccttggag gctagtatgc ctgtgggcag ctcggagcaa caggcttgct ggatgaagcg
    15781 gcagctggaa gagcttaacc aatacctgac tgacaaccaa tttttgtacc tatatagccg
    15841 aagcggccag acctatatgg acgagcagct ttttgtggcc gagcctgcag acgcgcttgt
    15901 tttgatgtac gcgagggaca gcgagccgga cggcggaaat acattctcct accttttggg
    15961 caagatccag gctgccgaag acctcgcggc ctacctgctg cggcgcatag cgttaaccag
    16021 ccagggggag cctgctgcgg aattggacaa acaggaagta cactgggatg gcagcctggc
    16081 gcaactctat gagatcggat acggcctttt tactgccggg ctggtaaggg gtaccgtaaa
    16141 aagtgtgatc gaacgcctgg gctatgcatt tgccgtaaag ccaggcaatt attaccggta
    16201 tatgctcaat atgaggatca gaaaaaaatc tccgacccaa tgcctggacc tgatgacgag
    16261 ttcgctgctg gaatacatgc gccaagccga cctcgatcct aaatacaaat aaactcttta
    16321 ttcccctaca ttgctatgtt agcagagatg aatgcattac actaccagct caaaagtgac
    16381 cttcagcata tggaagccac ggccatttcg ccattggcac aagcggacgc ctgctttagg
    16441 ctaacctcac tctactttgc gcagctcaaa cacatggtgg acgctcatgt attctcacca
    16501 caggagcaga tcaccttata caaatatata acgccaggat tcctggagga agtcatcttt
    16561 tatttgtcgt tgatcgacct ggagtccaga gatggagatg tcggccaact gcagcgctat
    16621 taccacgatg agctggaaag tgtcaagagc tttttggaac ggcaggattt tttgcgccag
    16681 tatatggcct tgggaaaaga gtacctggac gatattttat tcagtcatag gccaccggat
    16741 gccgaggttt tccctgaaag cctcggtttt gcgggaacag aatatttcaa cccccatagc
    16801 tacctggtcg caagaattgc agcatccctg cgcctgcatc gcttcctgga gcaaaaactt
    16861 gcaggcggaa cacctgcagc agatttaatg caaagtcccg agctgccact gccgggggga
    16921 cttccagacg ttccgccacc acagttgcaa atggtcatgg acgacatccg gcaaaaattc
    16981 agctggctta aaaccaaggt ggtgccgggc agcggcaatc aaagcaggct tttactgcag
    17041 gcacgaataa aatacaatct ccggttgttt aacgagcacc cgaaaacgaa ttcttaaaag
    17101 gccccgttct ttgtttagct aaaggttagg taagattcca actttttaat aacaaccctt
    17161 gccctcaggt cttccagggc atcctccatg accgtttcct ggttgggcgt cactacactc
    17221 gcctcacaca aatcccaaac ggctgccgct tgttgcttcc agtcctgaac cctggagatg
    17281 gtccggtcga tatcgataaa agggccggcc ttttggcgta ggtcatcaaa atccgtgtag
    17341 ggaaacaact ctaatttaaa cgcaaacaaa aaggcggctg ccagctccct ttgcgcctca
    17401 tggagtgttt cgacggtaag cagctcgccg cccgtacggt gcgcaaacat ttccacggcc
    17461 acgagtatga actccaagaa tttttcgggg acaagccccc atgccggcaa ggccttcaac
    17521 aaatccgtaa gtagttcttt atcgtagcgc ataggcatgt cccttccttt tcccggcagg
    17581 gggagcaggt aaaagtaaga ttttatagcc gtctgttttc tcagctgtgg attatgcttc
    17641 caaaaataat tttttgacac cttggcacca tagtgtcaaa aaccttatag ccggcgtcac
    17701 atttttgtat cgttaaacaa cggtactatc cttactaaat cagcaccaaa cgatgaagcc
    17761 gctcagtagc taccaacaga tcatggcctc ccgccttcat gcatccgaaa aagcaggaca
    17821 aactgtattg caacgttgtg gttcggccat tgcaatcgtg gaacaggtcc tgcaagaact
    17881 caacccggtc ctatccgata ctcagttctt aaatgccggc gaagaaatca attttttcaa
    17941 actgcaactt cctgccatcc acgcgcagct gatctaccac caatctgtat cctggctgga
    18001 gagccgtaag ccggtgggtg attacgcaat tcaccgccat tactatagca gtgagctgga
    18061 ccggatcagg cgctattcag aagaccaccg ggatttttac cagtaccatc gtacaggcgc
    18121 aacgtactgg gacgaacatt tgttccagcg cggccatgag ctgctgccgc agttacggca
    18181 tgagtactcc tttgctatgg atcgccggat caatacccaa ggcaccatgt tggtggctac
    18241 catgcaggca tacgacctgc tcagggaatt tatagaacag cagaccgctc aagttgactg
    18301 ccgcccggct gccgtaggca gtacggacca taagctgctg aaatggaccg atagcaagac
    18361 cgcactggcc gagatgatct acgctttctg gttcaagggt tccttcaata acggggccgc
    18421 cgagcttaaa gagattcagg cttacgttga gcagatcttc gacatccgca tcggcaatat
    18481 ctaccagatc aaacaagaga tgtacgcccg cgaaaatatt tccgcctacc aggacctgct
    18541 gcataaacgc ttcaaagaag gcatggagca gtcgctataa cacccctgta gccattgcaa
    18601 ttgcttatca ggtcgcttcc tatacctgtc gtttgaaact tccgactagg gattgcctat
    18661 gaatcccgca gcgtaaacgc tatcatattt gcttttgtcc tcttcccctc atttaaaatt
    18721 tctgctatga acattgaccg gatggaattt atggcgtgga tggagcggat catgaaccga
    18781 cttgacatcc tgggcgagca gatcagcgac gcacgaaaac aaaatggcag tatagacgga
    18841 gaggaactgc tggacaatca ggatattttg cagatgctga agatcagcaa ccgttcgctc
    18901 cagcgatacc gctctacagg ccggttgcca tactatacca tcagcggaaa actatactat
    18961 aagctcagcg atgtgcacca gttcgttcgg gaaagtgtca atgaccggat catgaagtct
    19021 acacttgtcg cagacaagta ccgccgatga cagccaatga ctgccaaacc caacttgggt
    19081 gcctgccgcc agttacattt ggatcgtacc cataaaatca aaaattatga gcgaacaaaa
    19141 tccggaaatg ccacaggcct ccgaccagct ttctgatatc ctgctggtat tcgacaaaga
    19201 aaaaatgaag atccaggcgg tcaaggatat cgataagaat ggtgagctaa ggacagtacc
    19261 gccaacgaaa aaaaaccaaa accagtttat gcgggtagac cggcatggcg atattttttc
    19321 caacttcttc gccaacttca tgagccagct gaaaaaccct acacggtttt ccttcttcaa
    19381 agtacctgtc catgaagcga taaaaacggc taaagagttg caggagcacg tcaacaaacc
    19441 aagtgaacag ggtcaagaac tcagcaaaaa actagaagta aaaaacgaac ccaaaccagc
    19501 aaataatcct gacatggaag taacacaaac aacaactccg cctagtgccg agccgcaaaa
    19561 ggtcccagag caaaggacag cccgatatca atccgagcaa gtagattggg attcgctcgc
    19621 aaaattcgga ctgagtaaag aaagccttga aaaggcaggc gtagtagacg atctgctcaa
    19681 aggttataag accaacaagc tccttccggt gacgatcaat acggataagg cggtttttag
    19741 gggagaagcc aggttgtctt tacgtacgaa tgacgagggt actgttatgg ctcaacttaa
    19801 tggtgttcgt caagaaccgg agctggatct gcccttcttc ggtcataagt ttaccgacga
    19861 agacaaaacc aacctccgca gtacgggcaa tatgggccgt gtcgttgacc tcaccaacat
    19921 gaaaacagga gaaaagatac cttcctatat tagtatagat cgcctgacca acgaggttgt
    19981 cgcctaccgt accagcacca tcaagatccc tgatgagatc aagggggtca agctggatga
    20041 ccaccagaag caatcccttg ctgaagggaa gcctacatac atcgagggca tggtctcggc
    20101 aaagaacacg cccttcaatg ctactttgca ggtaaacgcc gataagggct atattgaatt
    20161 catattcaat cgctcaatga atgcccaaca gacacttgat acgcagcagc gacaggacgc
    20221 cccacgtctg ttccgaggtt atgagcttaa cgatcagcag tataaaagat ataacgcagg
    20281 taagtcggtg gctgtaaatg ggcttgtcag caaggagggt aaaccatatg aaggttttat
    20341 caagttcgat tttgacacca ggaaagccat cttttcatat accgatccgg acaggattta
    20401 taagcaggca acccaaactg cagaaactcc aaagcaggac accggcaagg accaaataaa
    20461 tacgaatcaa aagcaggatc aaaaaaagcc caaaagtccc aaaaagtccg ccagcccaaa
    20521 aatgtaaatc aactaaccgg ttcgtaaaat gaaagcaata ctagcagaga aacccagcgt
    20581 cgcccgcgag atcgccgcgc tgctgggcgc cgatcataaa gaggacggat ttttatccgg
    20641 caataattac ctggttacct gggccatcgg ccatttggta acattggcca tgcccgaaga
    20701 ttataacatt acggggttta aaaaagaatc ccttcctata ctgccagctc cctatctgct
    20761 aaccgtccgg aaaataaaaa aggataaatc gtttgccgcc gatccagcag cggtcaaaca
    20821 actcaaggtc atccgggagg tttttggccg ctgcgacagc atcattgtgg cgacggatgc
    20881 cggtagagag ggtgagctga tattccgata tatctatgag cacctgggat gtcgcaaacc
    20941 ttttgagcgg ctgtggatca gtt
//
