LOCUS       NZ_FUWZ01000003        20936 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000003
VERSION     NZ_FUWZ01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 332908
            Orig. end                         :: 353844
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20936
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20936
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20936
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10936](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10936
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(650..665)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.09"
                     /tool="antismash"
     misc_feature    1749..1762
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     gene            2146..3837
                     /locus_tag="B5D63_RS20335"
                     /old_locus_tag="SAMN04488128_103316"
     CDS             2146..3837
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024181.5"
                     /locus_tag="B5D63_RS20335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103316"
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="WP_078670683.1"
                     /transl_table=11
                     /translation="MKNIQHRYIKVCIALALLGAGSCSKNFGDINTDPSLVSKPDVKFL
                     LSYSEDKIFTYQGTEWVWESMEQLMRFTQHVTSSPYEITNNVNTRYNTYYLQVLPNLNE
                     IRRQVDAMPDKEKYQKIKVVTNILMVLHGIKVTDMNGSIPFSEAVRGRYEQKYNPVYDE
                     QQALFANWLGQLNEAIKVLSDNSMVAQAVYGPSDIFYQSDWVKWVKLANTLKLRIAARL
                     ENADKAKCQAIFQEVMKDAIGPISDYDSQVRYVNATYVPFGTGGDIDYRSRRYASTSIM
                     NFLKKTNDPRLPVYFEKNDLVGSYKDSLAKYQVSLPAFIDPNDPLIMYQGGPADWTTNP
                     DVASYIGNPLPVSQFTKYSLISAINRRFFSPQLNQATGKFLDVAVTHAETCFYIAEFIQ
                     KGYAGGVDTKGSAEDWYKKGVTSSIQTMNAIAVAAGSTTAYSGDGQTEINNYLANPLVK
                     FNGVNNLERIYIQQFLGMYRQPNEAYVFCRRTGYPKTGSAYYGREPFNELIPRRFWLID
                     PGEVNRANWSAAMQQQGFTPNAQDLPTLSSQRIWYDKAAPDFGKGQ"
     gene            complement(4011..4850)
                     /locus_tag="B5D63_RS20340"
                     /old_locus_tag="SAMN04488128_103317"
     CDS             complement(4011..4850)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014218165.1"
                     /locus_tag="B5D63_RS20340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103317"
                     /product="universal stress protein"
                     /protein_id="WP_078670684.1"
                     /transl_table=11
                     /translation="MKKIVAILDGLSYSSSTVEYAVFIAKQEKAHLVGVFPKDINYRSY
                     AYYDLVDETGIPDQEMKSFAEKDTHTMGKSIQQFELACQQSGLNYSLHKDNDIAIEAVL
                     HESIYADLMIIESKEAFTRVKEEKPSHFLSQLFAEAVCPILVVPSEFTGISKSVLLYDG
                     SPSSVHAIRMFDYTLSGLKHIPTEVVSVKSPKSSLHLPDGKLMKEFMKRHYPQATFQVL
                     KGIPWEVIPAYLQEESSDTVIVLGAYRRSRLSRWFYPSMADILLQELRSPLFIAHCK"
     misc_feature    complement(4853..4866)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.3"
                     /tool="antismash"
     gene            complement(5069..5830)
                     /locus_tag="B5D63_RS20345"
                     /old_locus_tag="SAMN04488128_103318"
     CDS             complement(5069..5830)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lysine_decarbox"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008586044.1"
                     /locus_tag="B5D63_RS20345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103318"
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="WP_078670685.1"
                     /sec_met_domain="Lysine_decarbox (E-value: 1.3e-33,
                     bitscore: 111.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIDNKTPQLVVKKELPGYEEKYFLEGPRSRLKELFFSIKVLFEF
                     IRGFRVLHFAGPCIAVFGSARVKPGSDYYELGRKTGAGIAGLGFTVMTGGGPGIMEAAN
                     RGAKEAGGKSVGCNISLPKEQVANNYLDLRFSCKYFFVRKVLMFKYSYGFVILPGGVGT
                     LDEFSEALTLIQTHKILNFPLVLMNRGYWEPLMPLFHKMIENYMISPDDLQYILITDSI
                     DDAMKHLHKYAVEQYHAKRIKEFRRIVLFGE"
     misc_feature    complement(5933..5949)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 21.97"
                     /tool="antismash"
     gene            5965..6369
                     /locus_tag="B5D63_RS20350"
                     /old_locus_tag="SAMN04488128_103319"
     CDS             5965..6369
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS20350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103319"
                     /product="hypothetical protein"
                     /protein_id="WP_078670686.1"
                     /transl_table=11
                     /translation="MQIYISEEAIVADIQDRFQTLYPFLKLEFFRKPHAEGEYSPENEK
                     ISPDTLIEKIRTRHASGWIDISYYRTAAAVEYDFSHIFGLNTQILRKAGTLWLETVSTD
                     NWTLEELNNAGKPAKSRPFQLPDAPDVDNE"
     gene            6574..7332
                     /locus_tag="B5D63_RS20355"
                     /old_locus_tag="SAMN04488128_103321"
     CDS             6574..7332
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-162). E-value: 4.4e-12. Score:
                     38.2. Matches aSDomain:
                     nrpspksdomains_B5D63_RS20355_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF004818.0"
                     /locus_tag="B5D63_RS20355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103321"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_078670687.1"
                     /sec_met_domain="adh_short (E-value: 4e-38, bitscore:
                     127.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 5.2e-32, bitscore:
                     107.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIFHNKVAIITGGSFGIGRATAIAFAQEGAAVVIADCEEDPERE
                     TLRQIEANGGEATFIKCDVSKASDVAAMVEKTIGLYGRVDFAFNNAGIEGVSATTQECT
                     QENWQRTLAVNLTGIWLCMKHELYYMLQQGSGAIVNCASVAGLTGFPLLPAYVASKHGV
                     VGLTRTAALEYAKSGIRVNAVCPGVIKTPMIDRFTGNDKQIEQHFREMEPVGRMGEPAE
                     VAAAVVWLCSDAASFVTGTALPVDGGWTAQ"
     aSDomain        6595..7059
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS20355_PKS_KR.1"
                     /evalue="4.40E-12"
                     /label="B5D63_RS20355_PKS_KR.1"
                     /locus_tag="B5D63_RS20355"
                     /protein_end="162"
                     /protein_start="7"
                     /score="38.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIITGGSFGIGRATAIAFAQEGAAVVIADCEEDPERETLRQIEA
                     NGGEATFIKCDVSKASDVAAMVEKTIGLYGRVDFAFNNAGIEGVSATTQECTQENWQRT
                     LAVNLTGIWLCMKHELYYMLQQGSGAIVNCASVAGLTGFPLLPAYVASKHG"
     CDS_motif       6601..6678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5D63_RS20355_0001"
                     /evalue="7.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="B5D63_RS20355"
                     /protein_end="35"
                     /protein_start="9"
                     /score="12.2"
                     /tool="antismash"
                     /translation="IITGGSFGIGRATAIAFAQEGAAVVI"
     gene            complement(7345..8523)
                     /locus_tag="B5D63_RS20360"
                     /old_locus_tag="SAMN04488128_103322"
     CDS             complement(7345..8523)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (91-276). E-value:
                     6.8e-17. Score: 53.8. Matches aSDomain:
                     nrpspksdomains_B5D63_RS20360_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.5"
                     /locus_tag="B5D63_RS20360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103322"
                     /product="epoxide hydrolase family protein"
                     /protein_id="WP_200817054.1"
                     /sec_met_domain="PF00561 (E-value: 7.3e-13, bitscore: 44.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKFTIRIPDKDLEYLHQRLSNARWFDSAIESGWEKGVPASYLKK
                     MTGYWLNKFDWKKQEAILNQFPQFITAIDGQNIHYLHVKSPKPGAVPLMLIHGWPGSFA
                     DFIRVIRPLTEPQDAGQIAFDLVIPSIPGFGFSTPVKEKGWNMIRIATAFTTLMTQLGY
                     EKFAVHGGDMGAGIAGIMSGVAAYNLIGTHINTDFFAVAGLGMFPSDTSSFTKEENVRL
                     DRMKAYRKNGTAYLDIQATRPHTIGAALSDSPVGQLAWMVEKYKEWTDEDKNLPEDAID
                     TDQLLTNVSLYWFNQTGASGAEALAENMSMAFDWGGDSSQENSQWTPPKIPSAIACFGK
                     KEDESLLKKLTSLMGAPDKWTFYDSGCHFPAMEAPELLVEDIRQFYSDIISR"
     aSDomain        complement(7696..8250)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5D63_RS20360_Abhydrolase_1.1"
                     /evalue="6.80E-17"
                     /label="B5D63_RS20360_Abhydrolase_1.1"
                     /locus_tag="B5D63_RS20360"
                     /protein_end="276"
                     /protein_start="91"
                     /score="53.8"
                     /tool="antismash"
                     /translation="PLMLIHGWPGSFADFIRVIRPLTEPQDAGQIAFDLVIPSIPGFGF
                     STPVKEKGWNMIRIATAFTTLMTQLGYEKFAVHGGDMGAGIAGIMSGVAAYNLIGTHIN
                     TDFFAVAGLGMFPSDTSSFTKEENVRLDRMKAYRKNGTAYLDIQATRPHTIGAALSDSP
                     VGQLAWMVEKYKEWTDEDKNLP"
     gene            complement(8607..9125)
                     /locus_tag="B5D63_RS20365"
                     /old_locus_tag="SAMN04488128_103323"
     CDS             complement(8607..9125)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018627372.1"
                     /locus_tag="B5D63_RS20365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103323"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_078670689.1"
                     /transl_table=11
                     /translation="MAEWQKFSHLFKREEIPAKTRLLHEGEIARKVYFIEKGCCRLSFN
                     NDGKDITFQFFFEGEGVSSAESFRYDKPSLYSIESLEASVVHSLTKADYLTIVESSPLI
                     KQDIEEQTFRRLAYVEKLFLSRIKNSPEERYKELLQQYPRILQRVPQHYIASFLGITSV
                     SLSRIRNRR"
     gene            complement(9145..9846)
                     /locus_tag="B5D63_RS20370"
                     /old_locus_tag="SAMN04488128_103324"
     CDS             complement(9145..9846)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791123.1"
                     /locus_tag="B5D63_RS20370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103324"
                     /product="DUF1826 domain-containing protein"
                     /protein_id="WP_235021594.1"
                     /transl_table=11
                     /translation="MMIDLSGGEQHIRCVGSFHDLVATPFSGEINAICWARELTGDFSE
                     IVKKVTQSGNITEIEPAELRELQLSGEGALARDMLLQDMALLKAHGASPVLNVINYYDR
                     DDAFPFFPTDVYSFHVDRSPIPTDTFLCTYYGAASDILPNAQGEKKVLIPEIRAQLRKL
                     YHGAEEGFESFLSENFFDLHYQAKPEARPINLGVGNLWRLAVDHPESKVPPCLHRAPKE
                     RTGESRLLLIC"
     gene            10001..10936
                     /locus_tag="B5D63_RS20375"
                     /old_locus_tag="SAMN04488128_103325"
     CDS             10001..10936
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="B5D63_RS20375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103325"
                     /product="terpene synthase family protein"
                     /protein_id="WP_078670690.1"
                     /sec_met_domain="T1TS (E-value: 6.4e-50, bitscore: 166.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVSLPPLQYPYDTDGGPLRHPLEAQIEEDISNWIDHEYLFLTD
                     TQRVFYKQCRFGMISSCFYPLASNKALTIGARLVLLLFIHDDYTDNIDIHQLRPYLLKS
                     EAIMAGQAVPCRKGDLLYQFSLFRDALLPLVPAAWMQRWSCDLNYFYEGMIMERCFMPD
                     HYPSIPHYMFLREHLIGIYIYQDIVELYMSSFMPYALLSHPHVRELRRHAALIISWCHD
                     YYSAKRELAAGQMMNLVLVIRQAYQCSLEDAYAEAARVHIETAKAFLQLKDNPPDFGPY
                     NGLFREYAGHLLHMCKGNHLWHLHSGRYDQ"
     gene            complement(11035..12327)
                     /locus_tag="B5D63_RS20380"
                     /old_locus_tag="SAMN04488128_103326"
     CDS             complement(11035..12327)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS20380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103326"
                     /product="hypothetical protein"
                     /protein_id="WP_200817055.1"
                     /transl_table=11
                     /translation="MQIPLKSILLLLLPFASFAQKTVVPGSPDINASRLKPGKSLYTIY
                     YVKDNNWTKKGTYTHELSVSDNQLRFVADYIDEKGEWYRKRTSVADAKTFSPVSYKSEG
                     LKNSLDLTFGNTVTGKYRAMGEKDKPLTMKPAGKFVDFNLSELLFTTLPLDVGYKAIVP
                     EFYYGTSTDSVLSNYVIKDVKSYIQRSPKTGNHESWLVNVLEEESGAIYTYIIDKKDHR
                     IWQREMPVGKGTIEICVNEELDYQPIAAKFDKQENLRMLEKGNSVITGTAFARDRGGSK
                     LQVVNINKAQFAPRGTVVSILPNSAYIEEWKEVNRKIRKRKKIPEVPIDPNVAACIKKT
                     TVYDDKGHFEFTNLMPGEYILLTTFGYTHRYSYSYQSGTSNLVHPSGAVLSSSPIYSHG
                     SGATGATAEIEMKVTIRKDGDKVDVNLKDVR"
     misc_feature    complement(12469..12478)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(12561..12755)
                     /locus_tag="B5D63_RS20385"
                     /old_locus_tag="SAMN04488128_103327"
     CDS             complement(12561..12755)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS20385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103327"
                     /product="hypothetical protein"
                     /protein_id="WP_078670691.1"
                     /transl_table=11
                     /translation="MQRIGSFLIIIGLLAVILDFFNRVPRILAWIYEWGNGPAWAIKIG
                     LIVLGAILYLMGGKNLQKD"
     misc_feature    complement(12750..12762)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(12864..13487)
                     /locus_tag="B5D63_RS20390"
                     /old_locus_tag="SAMN04488128_103328"
     CDS             complement(12864..13487)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012790054.1"
                     /locus_tag="B5D63_RS20390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103328"
                     /product="response regulator transcription factor"
                     /protein_id="WP_078670692.1"
                     /transl_table=11
                     /translation="MIKVIIIDDHPIVLEGLKNLLSDREGVALAGCFDTGKAGLEALNY
                     LEPNVILLDINLPDISGTDICRQIRKRDKDVRIIALSVHNERPVIKNMLQSGANGYVLK
                     NSVGDEIITAIHTTLQGNNYLCRKTQEIMSVVREGDLLEIPQITRREKEILALVSQGLT
                     TPQIAEKLFISAHTVESHRKNLIEKFDVTSMTAVIKLAMQYKLI"
     gene            complement(13495..15738)
                     /locus_tag="B5D63_RS20395"
                     /old_locus_tag="SAMN04488128_103329"
     CDS             complement(13495..15738)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="B5D63_RS20395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_103329"
                     /product="sensor histidine kinase"
                     /protein_id="WP_078670693.1"
                     /transl_table=11
                     /translation="MMSRSLRVTYLLLIMLPAAVFVSAQTREDSLRGVLAQKALPLEQR
                     IPTMVRLAQTVFFNKDWAQGVRIYREALVLAAPLKDGQYRAHTYGGLLGAYYIMGDSIA
                     ARRCLDSAMWYARRTTSKKIQGYVQYMKGWMEVRSHKEIEAIRSLQQALALLEDEPAAA
                     VTRLSVYGELAFVYFQWYDLVNIEKYTRLALAEAPRTNSPDDLVSAHQDRGSYFINLYR
                     SNTADREALDSALWFMRRAFYIGQANRAKLAVPSSIPHSAIGIANIFLAFFANTDAIKD
                     SINYYNRIALEEARATKQFAVEVGVYNTLGSMAFEKGDYLDAIGYFRAAVDTGTKDILH
                     NKFDLSQSNLMLAESYERTGDTARALHHYKQYMTLYKAQFDEGKMNNARELEAKYEIAK
                     KEKDILEIRLLAEQRNRQLVQARVLAGQKDRDLLAARYAASLKDKALLAAEYEKGVRQQ
                     ALITANYKTAKREQELKVMGEQMTYNRNMNKIYAVLTIAFFLAGLFLYYAYRHRSKSLA
                     QTKKLHDLELGRLKQEHRISMLAATLEGQEKERTRLARDLHDGLGGLLSGVKIELSGLT
                     ALTTDPQQGTIVGKSLHHLDIAVDELRRIAQSMMPEVLLAYGLGEAAREYCNGLKKSGI
                     PVTCQVYHYKNDMDPNRQVSLYRIMQELVNNAVKHANATHILVQLQQSDTRIYLTVEDD
                     GDGLDKMQMTRLKGAGLANIQSRVEMLQGKLDVQSSPGTGTSFTVECLTTAEK"
     misc_feature    complement(15753..15766)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            15887..16216
                     /locus_tag="B5D63_RS20400"
                     /old_locus_tag="SAMN04488128_103330"
     CDS             15887..16216
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS20400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103330"
                     /product="hypothetical protein"
                     /protein_id="WP_078670694.1"
                     /transl_table=11
                     /translation="MATKINTPFRGYIPEYREIFRHNNPVEVCSPMHKRKKHCTFLYNA
                     FHSGKIYLLHFFTCYTSEAAYTQQNQTKEFYIGQLGFQPFGSQNPSSAHGVGEAMLAAL
                     QAAAR"
     gene            complement(16454..17377)
                     /locus_tag="B5D63_RS20405"
                     /old_locus_tag="SAMN04488128_103331"
     CDS             complement(16454..17377)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS20405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_103331"
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="WP_078670695.1"
                     /transl_table=11
                     /translation="MSISYIGKIIPSGTPRWLMGQTLHTAEKEKFKGYKDRGLEWGAIE
                     NGKLADIDFLELWPDNDSTTAIPPVVATLPNLKTLIIPSWFVPHLKAEDLPRGLEALQI
                     GVNSENKPKVNWNKELVLPDITLLDMGRVLSDFNAGNFPGLSNTLTITFGNKKLDASEI
                     GKCKHLKNLFLHKADTVETLSQAGAPSLHFAGWMEGKHEDFKGLKGYGEVRDAEIKWNK
                     KLTSLEGLEHLSKLEQLDISDCSKLEHLGDIMHIKTLQWFRIMESGKAWTAHIDDIKAK
                     FTKAGFEKIRFEPDGNYSLLEIKRKA"
     misc_feature    complement(17838..17858)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.48"
                     /tool="antismash"
     misc_feature    complement(18388..18399)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.54"
                     /tool="antismash"
     misc_feature    complement(20335..20350)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.66"
                     /tool="antismash"
     misc_feature    20733..20747
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.61"
                     /tool="antismash"
ORIGIN
        1 acttcggaaa actgttttca tggatccttc cccgtaacta tgacacgaaa tactggatgc
       61 agaaagccca ctacaccagc gtattcggag gagcgcccaa tccggcagac cccaatgaac
      121 ccaacaaagc gccggaatcg cgcttctggt tcagcctatt cgaaaatgaa tacctgcaga
      181 atgaacaaac catccgcgga cgcatagccc ttaccgctac cataacaccc tgggctaaac
      241 tgttactgga aggcaatgtg aacaacctgt ataccaagaa tgaaaacaag gaactgggac
      301 aaagccccga tttcaaaggc ggtctttatg gactcggaca taccagcaag gaaagctatt
      361 tcctcaaatg gatgctgatg atcaataaaa cccttatgaa agacctggag ctgagcggtt
      421 atgttggcgg tgaaacccag cgtttccaga ccacctttaa ctacagcgaa accgtaggcg
      481 gactgaacta tccgggccag tttttcctgg gtaattctgc acaaaaaatg gaacccaaag
      541 gcggacttaa aaccaaaaaa gcctttaact ccctttatgc cagcgccgat ctggcctgga
      601 gaaaccagct gttcctgcag gccactttcc ggggcgactg gtcctctgca ctggcctata
      661 ccaatggcgg cggcaacttt ttttacaatt acccggccgt tagcttatca tggctgttct
      721 ctgaaacctt caaactgcct tcatggatca gttacggaaa gttgagaggc aacgttgcag
      781 cactgggtaa cgataccgat ccgttcacca tcaacccggg attcaccttc aatggcttca
      841 cttcgtccaa tgggaccgat attcctatgt ccacctatag ccgctaccgt gacccgctca
      901 ccggcaagct gatggtaata cagcccaacc tgcggccaca acggaaaata gccaaggaat
      961 taggcgttga aatgcgtttc ctgcaaaaca ggatcggctt tgacttatcc gtataccagg
     1021 acaacaccag ggaccagatc ctggacgtag ccacccctcc ggaaagcgga caggatggaa
     1081 ttatcatcaa cgcaggaaat atccagaaca ggggacttga actgatgatt gacggaacac
     1141 cggttaaaac aaagaacttc gaatggagca ccaacctcaa ttattccttc aaccgcaacc
     1201 ttattaaaga tttatacccc ggacggacag aatacgacct gggagccaat atcggcgaaa
     1261 tcagcacctg ggcggtagta ggcaagtcat atggcgtatt acgcacactg attcattcca
     1321 gtccatacca ggccaaagat gccaatggca acgcggtaga tgaccccaac aatggcaaac
     1381 cggtactggc ctggcgctct gatgcccgtg ccgcattccc tgcccgtagc aatacctggc
     1441 aggatgtggg cgatatcaat gccaaattca gggcaggctg gggcaacacc ttccgatata
     1501 aaggcttttc cctgaatgta ttgctggatg ctaaaatagg aggcgatttt gtactcctca
     1561 cctaccgcta cggcacccac accggcgtgt tccccaatac cctggcagga cgggatgccg
     1621 ccaccggcgg tattacctgg accagcaaat acgatggcca gacctacgac gatggcctga
     1681 tcccggatgg cgtattcccg aaaggccaga tgataacaca gcccgacgga tcacaggtgg
     1741 acgtaggcgg catgagctat gcacaggctt acgaaaaagg atatgtagaa cctacccatg
     1801 ctccgcagtt ttactaccgc tatggctctt cctccaccgg ggtggccgat tactggatca
     1861 aaaagaatac ctgggtatca ttacggcagg tatcgctggc ctaccagttc ccggccagta
     1921 tctgcaaaaa actgatgctg aataacctga gcgtggcagt tgtaggccgc gacctgttgt
     1981 acctctacaa cagtcttcct tacaactata accctgcttc caacaactcc aacaacaccg
     2041 cctattccgg tgaagaagga tttttaccaa tgatccggtc aattgcaggt acgatcaggg
     2101 taggattctg ataaacagtt tgttgcaaca tcaaaaaaag agatcatgaa aaacatacaa
     2161 caccgatata taaaggtttg catagcgctg gccctgctgg gcgccgggtc ctgttccaag
     2221 aattttggcg atatcaacac agaccctagc ctggtgagca aaccggatgt aaaattcctg
     2281 ctcagctatt cggaagacaa gatcttcacc taccagggca ccgaatgggt atgggaaagc
     2341 atggaacagc tgatgcgctt tacacaacat gtaacttcca gcccgtacga aattaccaac
     2401 aacgtcaata cgcggtataa tacctattac ctccaggtac tacccaacct gaacgaaatc
     2461 agacggcagg tggatgctat gcccgataag gaaaaatatc agaaaataaa ggtagttacc
     2521 aatatcctga tggtgctgca cggtattaag gttacagaca tgaatgggtc catccccttt
     2581 agcgaggcag taagagggcg gtatgaacaa aagtataatc cggtgtacga tgagcagcag
     2641 gcacttttcg ccaactggct gggacagctc aatgaggcta ttaaagtact gtctgataat
     2701 tcaatggtag cgcaagcggt ttacggacca tccgatattt tttaccagag cgactgggtg
     2761 aaatgggtaa aactggccaa tacgcttaaa cttcgtatag ccgccaggct ggaaaatgca
     2821 gacaaggcaa aatgtcaggc catcttccag gaagttatga aagatgctat cggccccatc
     2881 agcgactatg attcgcaggt caggtatgtt aatgctacct atgttccttt cgggaccggg
     2941 ggagatattg attaccgcag ccgcagatat gccagtactt cgattatgaa tttcctgaag
     3001 aaaaccaatg atccccggtt accggtatac ttcgaaaaaa atgacctggt aggcagttat
     3061 aaagattcac tggccaaata ccaggtatca cttcctgcat tcattgatcc gaacgatccg
     3121 ctgatcatgt accagggagg accagccgac tggaccacca atcccgatgt ggcatcctat
     3181 atagggaacc cgctacctgt aagccagttc accaaatact ccctgatctc tgctatcaac
     3241 cgcaggtttt tctctcctca actaaaccag gcaaccggta agttcctgga tgttgccgtt
     3301 acccacgcag aaacctgttt ctatatagct gagtttatcc agaaaggtta tgccggtggc
     3361 gtggacacca aaggcagtgc ggaagactgg tacaaaaaag gagttacctc ttcgatacag
     3421 accatgaatg ccatagcagt agccgcaggc tccaccactg cctattccgg cgatggacaa
     3481 acagagatca acaactacct ggctaatcca ttggtgaaat tcaatggcgt caataacctg
     3541 gaaaggattt atatccagca atttctgggg atgtaccggc agcccaacga agcctatgta
     3601 ttttgcagac gtaccgggta tcccaaaacc ggctcggctt actatggcag ggaaccattc
     3661 aacgagttga tcccccgccg cttctggctg atagatcccg gagaagtgaa cagggctaac
     3721 tggtcggccg ccatgcagca gcagggattc acacccaatg cgcaggactt gcctaccctg
     3781 agttcacagc gcatctggta cgataaagcc gctcctgatt tcggaaaggg gcagtaacat
     3841 caaaagaagc acttacaatc aaacgtaagt gcttcttttt tttgtatcct ccagcagtaa
     3901 agtgacgttg tcaaaattcg tcgggcgttg aaaagccgga agaaactgag aaaaaacatg
     3961 aattcaggct tacacagcag gaagaatcct aaagcccgta gacagtatga ctatttacaa
     4021 tgtgcaataa ataacggcga tctcagctcc tgcaatagaa tatctgccat acttggatag
     4081 aaccatcgtg ataaacggct tcttcggtat gcacccagaa cgataactgt atcagaactc
     4141 tcttcctgca aataagccgg aattacctcc cacgggatac cttttaatac ctgaaacgtc
     4201 gcttgcggat aatgcctttt cataaactcc ttcattaact ttccatccgg aagatgaagg
     4261 gaagatttcg ggctttttac cgaaaccacc tcagtcggta tatgcttcaa accggaaagc
     4321 gtatagtcga acatgcgtat ggcatgcacg gaagaaggcg aaccatcgta caataatact
     4381 gatttactta taccggtaaa ctcagacggg accaccaata ttggacagac cgcctctgca
     4441 aacagttgac tgagaaaatg cgaaggtttt tcctctttca ccctggtgaa cgcctccttg
     4501 gattctatga tcataaggtc agcataaatg ctttcgtgta atacagcctc tatggcaata
     4561 tcgttatctt tatgcaacga gtagtttagg ccagactgct gacatgccaa ctcaaactgt
     4621 tgtatactct ttcccattgt atgcgtatcc ttttcagcga aacttttcat ctcctggtcg
     4681 ggaatacccg tctcatcaac aaggtcataa tatgcataac ttctataatt aatatcttta
     4741 ggaaatacac ccaccaaatg cgccttttcc tgtttggcaa taaatacagc gtattcaacg
     4801 gtactactcg aataactcaa accgtccaaa atagcaacta tctttttcat acttttaatt
     4861 taaaaagatg acataaaata aaaggctata aatagatctg gaaatgcctc tgttcaataa
     4921 taaaattaat agcgttccag ctgaaaagta atgacatcgg tcagatcggc ttctgattca
     4981 aatcatccat gacagtgctt ctgcagccaa ttaggagtag aatatttttg cctggccggc
     5041 acctcgtgaa attccgactt gcaggcacct attccccgaa aagcacaatc cggcgaaatt
     5101 cctttatccg ttttgcatga tattgttcga cagcatattt atgaagatgt ttcatcgcat
     5161 cgtcaatgga atccgttatc aggatatact gcagatcatc gggtgatatc atataattct
     5221 cgatcatttt atgaaacaat ggcatcaatg gttcccaata tccgcgattc atgagcacca
     5281 atggaaaatt gagaatttta tgggtttgaa tcaaggtaag cgcctcagaa aactcgtcca
     5341 gcgtacctac ccctccaggc aggataacga atccgtaaga atatttgaac ataagcactt
     5401 tacgcacaaa aaaatacttg caactaaagc gcaggtcaag atagttatta gccacctgtt
     5461 cctttggcag actgatattg caacccactg attttccacc agcttctttt gcgcctctgt
     5521 tagctgcctc cattatcccc ggaccgccac cggtcatgac ggtaaaacca agtcctgcaa
     5581 taccggctcc tgtttttcgc cccaattcat aatagtctga tcctggtttt accctggctg
     5641 atccaaatac agcgatacaa ggtcccgcaa aatgtaatac cctgaatcca cgaataaatt
     5701 caaacaacac tttaatagaa aagaataatt cttttagtct cgagcgtggt ccttccaaaa
     5761 aatacttctc ttcatatccg ggtagttcct tcttgactac aagttgcggt gttttgttat
     5821 ctataatcat aggtcgaaca ttagaaagtt aatttaccac agtttcatcc ccgatattat
     5881 gaccgttatc atgaagcagt gtgattatcc tcattttcct atatccaaaa cgatgctata
     5941 ttgtattgac caaacctatt ttttatgcag atatatatta gcgaagaagc tatagtagca
     6001 gacatacaag acaggtttca aaccttatat ccattcctga aactggagtt tttcaggaaa
     6061 ccacatgccg aaggtgaata ctctcctgag aacgagaaaa tatcaccgga tacgcttatc
     6121 gaaaaaatac gaacacggca tgcttccggt tggattgata tcagctacta tcgcaccgct
     6181 gccgcagtag aatatgattt tagccacatc tttgggctaa acacgcaaat actccgcaaa
     6241 gcaggaacac tatggctgga aactgtcagt acagataact ggaccctgga agagttaaat
     6301 aatgccggta aaccggcaaa gagccgccca tttcaattac cggatgcgcc ggacgttgat
     6361 aatgaatgac agtgatattc cgtttcctca tcatttaatt tgcctgacat accttggctt
     6421 taataaacaa gcaacaaatt tcagtatcga tactcaataa aaattgatac tacatgattt
     6481 ccggcattct cctgtttagc gggtccgctt cccgccgtat gattttgaaa attttattga
     6541 aaatgagtat tcataacaaa aaaatctgaa aacatgccaa tattccataa taaagtggcc
     6601 attattacgg ggggtagttt cggtattggc cgcgctacag ccatcgcatt tgcgcaagag
     6661 ggtgcggcag tggtgattgc agattgcgag gaagatccgg agagggagac actccgccaa
     6721 atagaagcga acggtggcga ggccacgttt ataaaatgtg atgtgagtaa ggcttctgac
     6781 gttgcggcga tggtcgaaaa aactattggc ctatacggca gggtggactt cgccttcaac
     6841 aacgcaggca tcgagggtgt ttccgctact acgcaggagt gcacacagga gaactggcaa
     6901 agaacgctgg ctgtgaacct gaccggcatt tggttatgca tgaaacatga gctctattat
     6961 atgttacaac aaggtagcgg cgccatcgtc aattgcgcat ctgtagccgg attgaccggc
     7021 tttcctttac tccctgccta cgtagccagt aaacacggtg ttgtagggct taccaggacg
     7081 gccgcgctgg agtatgctaa atccggtatt cgggtaaatg ctgtttgccc gggggttata
     7141 aaaaccccta tgatagaccg ctttaccggg aatgacaaac aaatagaaca gcatttccgg
     7201 gaaatggaac ctgtagggcg tatgggtgaa cctgcagaag tggcggcagc cgtagtatgg
     7261 ctttgctccg atgccgcatc ttttgttact ggcactgccc tcccggttga cggcggctgg
     7321 accgctcaat aactttatct ttcattatct acttataatg tccgaataaa actgccggat
     7381 atcctccacc agcaattccg gcgcctccat ggccggaaaa tgacaaccgc tgtcatagaa
     7441 ggtccattta tccggtgctc ccatcagcga cgttaatttt ttcaacagag attcatcttc
     7501 ttttttacca aagcaggcga tggctgatgg aatcttcggc ggtgtccatt gactgttttc
     7561 ctgagaactg tcaccacccc agtcgaaagc catactcata ttttcggcaa gggcctctgc
     7621 gccggacgct cctgtttgat taaaccagta cagggaaaca ttggtcaata gctgatctgt
     7681 atcaatggcg tcttcgggta agtttttgtc ctcatctgtc cattctttat atttctccac
     7741 catccaggcc agctgtccaa ccgggctgtc cgataaagcg gcgccaatag tatggggtct
     7801 tgtagcctgg atatccaaat aggccgttcc atttttcctg taggctttca ttcggtccag
     7861 ccgcacgttt tcttcctttg taaaagacga agtatcggaa ggaaacattc ccagtcctgc
     7921 taccgcaaag aaatcagtat taatatgagt gccgatcagg ttgtatgcgg ccaccccaga
     7981 catgatacct gcaataccgg ctcccatatc gcccccatga actgcaaact tttcgtaacc
     8041 cagctgggtc attaaagtag tgaacgcagt ggcaattctt atcatattcc atcccttttc
     8101 ttttacaggc gtggaaaaac cgaaacccgg gatagatgga atgaccaggt caaaagctat
     8161 ttggccggca tcctgcggct ccgtaagcgg ccggatcacc cttataaaat ccgcaaaaga
     8221 ccccggccag ccatgaataa gcatcaaagg aacagcgccc ggcttcggtg atttgacatg
     8281 cagataatgg atattctgtc catcaattgc tgttatgaac tgtgggaact gattgagaat
     8341 agcctcttgt tttttccagt caaatttatt cagccaatag ccagtcattt ttttcagata
     8401 gctggcaggt acaccttttt cccagccgct ttcaattgcg gagtcaaacc aacgggcatt
     8461 agagagtctt tggtgaagat attcaaggtc cttgtctgga atccggatcg tgaacttttg
     8521 catagctttc aaattttgat tgttaatttt cttacgtcaa aattcatcat tatacaaatg
     8581 gaggacgata acaattgtta attaatctaa cgcctgttcc tgatccggct cagcgaaacg
     8641 gaagtgatgc ccaggaaaga agcaatgtag tgttgtggta ctctttgaag aatccgggga
     8701 tattgttgca gcagctcctt atatcgttct tcgggactgt ttttgatcct ggacaggaaa
     8761 agcttctcca cataggcaag ccgccgaaaa gtctgttctt ctatgtcttg cttaataagg
     8821 ggtgagcttt caacgattgt aaggtaatcc gctttcgtga gggaatggac tacagatgcc
     8881 tcaaggctct ctatggaata gagactgggt ttatcgtacc ggaaactttc ggcagacgaa
     8941 acaccctctc cctcaaagaa aaactgaaag gtaatatctt taccatcgtt attgaaagaa
     9001 agcctgcaac atcctttctc aataaaataa acttttctgg caatctctcc ttcatgtaat
     9061 aagcgcgttt ttgcaggtat ctcctcccgc ttgaacaggt gactgaattt ttgccattct
     9121 gccatcttaa tataatattt aaagtcagca aatcaacaat aaccggctct ccccggtcct
     9181 ttcctttggt gcacgatgca gacagggagg caccttgctt tcaggatggt ccaccgccag
     9241 ccgccacagg ttaccaaccc ccaggtttat gggacgcgcc tcaggcttag cctgataatg
     9301 caggtcgaaa aaattctcac tcaggaacga ttcaaaacct tcctcagctc catgatacag
     9361 cttcctgagc tgcgcacgta tttccggaat aagtaccttt ttttctcctt gtgcattagg
     9421 cagtatatca ctcgccgcgc catagtaggt gcataaaaag gtatcggtag gtatcgggga
     9481 gcgatctacg tgaaaagaat aaacatcggt cggaaaaaac gggaaggcat cgtccctgtc
     9541 atagtagttg atcacattta gaacgggcga tgccccatgc gctttcaata gcgccatatc
     9601 ctgtaacagc atgtcgcggg caagcgcccc ctctccgctc aactgaagtt cacgaagctc
     9661 cgctggttca atttccgtta tgtttccgct ctgcgttacc tttttgacga tctcagaaaa
     9721 atcgccggtt agctcacgcg cccagcaaat tgcatttatt tctccactaa agggtgtggc
     9781 gaccaggtca tgaaaactcc ctacacagcg aatatgttgt tcaccaccgg ataaatctat
     9841 catcatagtt tacataaaat caatgggcaa cgataaccga ccgctgcctt catataaagg
     9901 tagccaatga taattataaa agacggatgc cacgtcaatg aattttcccc gcggtgagac
     9961 agcgtatttt tatatgtgac gttgatctca attaaagcct atgtctaccg tatcactgcc
    10021 ccccttacag tatccctatg atacggacgg gggaccgctc cgccatccgc tggaagcgca
    10081 aatagaggaa gatatcagca attggataga ccatgaatac ctgtttctga cagatacaca
    10141 gcgggtattc tacaaacaat gccgttttgg gatgatttct tcctgctttt atcccctggc
    10201 cagcaacaag gcattgacga taggcgccag actggtattg ctgttattta ttcacgatga
    10261 ttatacagac aacatcgaca tccatcaact gcggccttat ctgctcaaaa gcgaagccat
    10321 catggcaggg caggctgtac cttgccggaa aggggacctg ctttaccagt tcagcctgtt
    10381 cagagatgcg ttgcttccgc tggtaccggc agcatggatg cagcgctgga gctgtgacct
    10441 caattatttt tatgaaggga tgatcatgga gcgttgtttt atgcctgatc attacccttc
    10501 catcccgcat tatatgttcc tgcgcgagca tttgatcggc atatatattt accaggacat
    10561 cgtggagctt tacatgtcat cctttatgcc ttatgcgttg ctgtcccatc cgcatgtcag
    10621 ggaactcaga aggcacgccg cgcttataat atcctggtgc cacgactatt attccgccaa
    10681 aagggaattg gctgcgggac agatgatgaa cctggtcctg gtgatcaggc aggcgtatca
    10741 atgcagcctg gaagacgcct acgctgaagc tgcacgtgtc catattgaaa cggcgaaggc
    10801 atttttgcaa ctgaaagaca acccgccgga ttttggtccc tataacgggc ttttcaggga
    10861 gtacgccggc caccttctgc acatgtgcaa aggcaatcat ttatggcatc ttcattcagg
    10921 gagatatgat cagtaagacc gctcccttct ccataataaa gaagccttcc ccctgtaaca
    10981 gacggaaggc ttcttttatt tattcctttt gggaaagatt cttcttaaca gttcttaccg
    11041 cacatctttc aggttaacat ctaccttatc tccatctttc ctaatcgtca ctttcatttc
    11101 aatctcggca gtagcgcctg tagccccgct gccatggctg taaatagggc tggatgacaa
    11161 caccgctcca ctgggatgca ccaggttgga agtcccagac tgatagctat aagaataacg
    11221 gtgtgtataa ccaaaagtgg tgagcaatat atattcgccc ggcatcaggt tggtaaactc
    11281 gaaatggcct ttgtcatcat acacggtcgt tttcttaata caggcggcaa cgttaggatc
    11341 gatcggcact tcggggattt ttttacgttt ccggatttta cggttcactt ctttccattc
    11401 ttctatatag gccgaattag gcagaatgga caccacagtg cctcgggggg caaactgcgc
    11461 cttgttgata ttcaccacct gtaatttact gccgccacgg tccctggcaa aagcggtacc
    11521 agtgataaca ctgttgcctt tctccagcat tctcagattt tcctgcttgt caaacttagc
    11581 agctatcggt tgatagtcca gttcctcatt cacgcagatt tctatggtac ctttaccaac
    11641 aggcatctcc ctttgccaga tccggtgatc ttttttatca atgatgtagg tataaatcgc
    11701 gccggattct tcttccaata cattcaccag ccagctttca tggtttccgg ttttagggga
    11761 acgctgaata tagcttttta cgtcttttat cacgtaattg gacaatacgc tgtcagtact
    11821 ggtgccatag taaaactcag ggacaatggc cttgtaacct acgtccagcg gcaaggtggt
    11881 aaacagcagc tccgacaagt taaagtcaac gaacttcccc gccggcttca tcgtcagcgg
    11941 cttgtccttt tcacccatcg cgcggtactt accggtaacc gtgtttccga aagtgaggtc
    12001 cagggaattt ttcagtcctt cagatttgta gctgacaggg ctgaacgttt ttgcgtccgc
    12061 tacggaagtc ctcttccggt accactctcc tttttcatcg atatagtcag ccacaaaccg
    12121 tagctgatta tccgaaacgg ataattcatg ggtatacgtt cccttctttg tccagttgtt
    12181 atccttcaca tagtaaatgg tgtataacga ctttccgggt ttcaaacggc tggcattaat
    12241 atctgggcta ccgggtacaa cagttttctg tgcaaagctg gcaaatggca gtaacagcag
    12301 cagaatagat ttcaatggaa tttgcatgaa gtccttgttt tcttaccaat tataattata
    12361 acttatattt aagtcctttc ttaaggggca aaaataaacg atttccggca aattggcagg
    12421 ataacgctcc ctacatcata tctagataag tataaaacaa cacacccctc aaaaaacaag
    12481 acctgtaagg tgatgaaacc tcacaggtct ttgttggcat gaaagtactt cataaaacaa
    12541 tggtgaaagg ccaggagata ttaatctttc tgcagatttt taccgcccat aaggtacagt
    12601 atcgctccta atacaataag gccaatctta atagcccagg ccggaccgtt cccccattcg
    12661 tagatccagg ccaggatacg gggcacacgg ttaaaaaaat cgagaattac agccagcaga
    12721 ccaataataa tcaaaaagga gccaattctt tgcataatga aatattgctt aaatggattg
    12781 aaaaatacaa ttgatggtaa tacaaaatta gtgtcaggcg tcgtcagcta tatccctgaa
    12841 aacagcgatt tttagcactt agatcatatc aatttatact gcattgccag tttaatcact
    12901 gctgtcatgg aggtgacgtc aaatttttcg atcaggtttt tccggtgact ttctaccgta
    12961 tgcgcactga taaaaagctt ttcggctatc tgcggtgttg tcagtccctg gctcaccagc
    13021 gccagaattt ctttttctct tcgggtaatc tgcggtatct ccaaaagatc gccttccctt
    13081 acaacgctca tgatctcctg cgttttccgg cagagataat tgttgccctg caacgtggta
    13141 tggatagcgg taataatttc atcccctacg gagtttttga gtacataacc attggcgccg
    13201 ctttgcagca tatttttaat gaccggccgt tcgttatgta cgctcagtgc gataatcctt
    13261 acgtccttgt cccgcttgcg tatctggcgg cagatgtccg taccgctgat atcaggcaga
    13321 ttaatatcca gcagtattac gttgggctcc aggtagttga gcgcttccag tcccgctttt
    13381 ccggtatcaa agcaaccggc aagcgctacc ccctcccggt ccgaaagcag gttttttaac
    13441 ccctccagca caataggatg atcatctatt ataatcactt taatcatatc gttactattt
    13501 ttcagccgtt gttaaacatt caactgtaaa gctggtccct gttccgggcg acgactgcac
    13561 atccagctta ccctgcagca tttctacgcg ggactgtata ttggccagcc cggcgccttt
    13621 cagccgggtc atctgcattt tgtccaaacc atccccgtca tcttccaccg tcaggtaaat
    13681 acgggtatcg ctttgctgca gctggaccag tatatgcgtg gcattggcgt gtttcacggc
    13741 attgtttacc agctcctgca taatacggta caacgacacc tgccggttag ggtccatatc
    13801 atttttataa tgatatacct gacaggtgac agggatacct gattttttca agccgttgca
    13861 atactcccgc gcagcctcgc ccaatccata agccagcaat acctccggca tcatactctg
    13921 tgcgatacgg cgcagctcat ccacagcaat atcgaggtgg tggagcgatt taccgacgat
    13981 ggttccctgc tgcgggtcgg tggtgagcgc cgtcaggccg gacaattcaa tcttcacccc
    14041 cgacaacagg ccgcccagcc catcatgcag gtcgcgcgcc aggcgggtac gttccttctc
    14101 ctgcccttcc agcgttgccg ccaacatgga aatgcggtgt tcctgcttta acctgcccag
    14161 ctccaggtca tgcagctttt tggtctgcgc cagcgatttg gagcggtgtc ggtaagcata
    14221 ataaaggaaa agccctgcca ggaaaaaagc gatggtaagt accgcataaa ttttgttcat
    14281 gttccggttg taggtcatct gctcccccat cacttttagc tcctgctcac gtttagccgt
    14341 tttgtaatta gcggtgatca gcgcctgctg tctcaccccc ttttcgtact ccgccgcgag
    14401 caacgccttg tcctttagac tagcggcata gcgcgctgcc agcagatcac ggtctttctg
    14461 cccggccagc accctcgcct gcaccagttg ccggttgcgc tgctctgcca gcaggcgtat
    14521 ctccaatata tctttttcct ttttggcgat ctcgtattta gcctccagct cccgcgcatt
    14581 attcatcttg ccctcgtcga actgtgcttt gtagagcgtc atatactgct tgtaatgatg
    14641 caacgcccgg gctgtatctc ccgtacgttc ataagattcg gccagcatca ggttagattg
    14701 cgagaggtcg aatttattat gcagtatatc tttcgtgccg gtatcaacag cagcacggaa
    14761 atagccgatg gcgtcaaggt aatcgccttt ttcaaaagcc atgctgccca gcgtattgta
    14821 cacgcctact tccacggcaa actgcttcgt ggccctggcc tcttccagcg ctatccggtt
    14881 gtaataattg atactgtctt taatcgcgtc tgtattggca aaaaaagcga ggaagatgtt
    14941 ggcgataccg atggcggaat ggggaatact gctgggaaca gccagcttcg cccggttagc
    15001 ctgaccaata taaaatgccc tgcgcataaa ccagagtgca gaatccagcg cttcccgatc
    15061 ggccgtattg ctacgataaa gattgataaa atagctcccc ctgtcctggt gggcgctcac
    15121 aaggtcgtcc gggctgttgg tgcgcggcgc ctccgccagc gccagccggg tatatttttc
    15181 aatattcacc aggtcgtacc actgaaaata aacaaaggcc agctcaccat acacagacaa
    15241 ccgtgttacc gcggctgcgg gttcatcctc cagcaacgca agcgcttgct gcaggctgcg
    15301 gatagcttct atctctttat gggagcgtac ttccatccag cctttcatat actgcacata
    15361 accctgtatt tttttgctgg tcgtacgccg ggcataccac atggcactgt ccaggcagcg
    15421 acgggccgct atactatcgc ccataatgta ataggccccc aacagcccac catacgtatg
    15481 cgcccggtat tgcccgtcct tcagcggtgc cgccagcacc agcgcctcac gataaatccg
    15541 tacgccctgt gcccagtcct tattgaaaaa tacggtctgc gccaatcgca ccatggtagg
    15601 tatgcgttgc tccaatggca acgctttctg cgccagcaca ccgcgcagcg aatcttcccg
    15661 ggtttgggca gaaacaaaaa cggccgccgg caacatgatc agaagcaggt aggtaacacg
    15721 taaagaccgg ctcatcattt tttaaccgtt aatttttttc aaaactgcca ttcatcaagc
    15781 atgctaaaat agccggtttg ggttaatgtt ctgattatta atgttgtttt cgaattacaa
    15841 acataacaca tatgtcccaa tgacacaaac gcaccttcgc tcatcgatgg ctacaaagat
    15901 aaataccccg ttccggggat atatccctga atacagggag attttccggc ataataaccc
    15961 cgtggaggta tgctccccca tgcacaaacg aaaaaagcat tgtacattcc tgtacaatgc
    16021 ttttcattcc ggtaaaatct acctactgca tttctttacc tgctatacat ccgaagctgc
    16081 ctatacgcaa caaaaccaga caaaggaatt ctacattggt cagttaggtt ttcagccatt
    16141 cggcagccag aacccttcct cggcccatgg cgtaggggaa gccatgctcg cggcgctaca
    16201 ggcggcagcc cggtaaccat ctctgtcagc aagatatgtt agccttacag cctgttgctg
    16261 taaggctttt tgcgctcgcg gcaatttttt aaagtctcac tgcacctgtt taagcgattt
    16321 gactgtcttt agtaaaaagg ctgcaagctg cagcatgttt tttggttttc tagatgataa
    16381 agaattaggc taaaagaaaa ccgctcctct tttcagggaa gcggttcttt ttatcattaa
    16441 agcaggatgc ggtttatgct tttcgtttaa tttccagcaa cgagtaattg ccatccggtt
    16501 caaaccgtat cttttcaaat cctgctttgg taaatttcgc tttgatatcg tcgatatggg
    16561 cggtccaggc tttgccactc tccataatac ggaaccattg cagggttttg atatgcataa
    16621 tatccccgag gtgttccagt ttggagcagt cggagatatc cagctgttcc agtttggaga
    16681 ggtgctccag tccttccagc gaggtcagtt tcttgttcca tttgatttca gcatccctta
    16741 cttcgccata ccctttcagg cctttgaaat cttcatgttt gccttccatc cagccggcga
    16801 aatgcaggga gggggcgcca gcctgactga gggtttccac ggtatccgcc ttatgcagaa
    16861 agagattttt caggtgttta cattttccga tttcggacgc gtccagtttt ttattgccaa
    16921 aggtaattgt gagcgtgttg gagagaccgg ggaaattgcc ggcgttgaag tcagacagta
    16981 cccggcccat atccagcaag gtgatatccg gcagcaccag ttccttgttc cagttcacct
    17041 tcggtttgtt ttcactgttg acccctatct gcaatgcctc caggccgcgg ggcaggtctt
    17101 ccgctttcag gtgcggcaca aaccaggaag ggatgatcag cgttttcagg tttggcaaag
    17161 tggccactac cggcggtata gcggtggtgc tatcattatc cggccacaat tcaaggaaat
    17221 cgatgtccgc cagcttacca ttttcgatgg cgccccattc cagccctctg tctttgtatc
    17281 ctttgaactt ttctttttct gcggtatgca gcgtttgccc cataagccac cggggagtgc
    17341 ccgatgggat gattttaccg atataactga tagacattcc tgatgctttt aatttaaatg
    17401 cgttattcaa tccagtctgc gccggcttta ttgcgttctc ccaggaattc gtccaccctg
    17461 ttttccgcgg ctgcacggat gtcattctga gagccgttca tcttgggcac gttgccctgt
    17521 tcatccatca cttcctgttc aaagctgcgc agcacatggt ttttagctct tctttctgaa
    17581 ataggtattt tactcacatc gcccatgtcc acctttttga tcgtaacggt tactccctct
    17641 ctcagcttat cattttcatc aaacaacatt tcagttgctt ttttgtggct tttttctcca
    17701 ctggccaacc ttaccacgag atcatcaccg gaccccgtat acaccttgcc gtcgtattcg
    17761 atatgatata cccccggtcc gtccggtacg cctatttccc tcaactgtgc cctgcggcat
    17821 tccagcccga acggatcaat ataggcattg ggatctttca cataggcgta caaggtagcg
    17881 ccattgccga gcagtccgat agggtcctgg ctgatatact gtccttcttc cgggctgtaa
    17941 taacggaaac ggttatagta caagccggtc tccacatctt catactgtcc ctggaaccgg
    18001 aacggaacga agtccttgct cccttcgaac ttacgcacat ttccataaat atccaattcg
    18061 gcgctccata ttttctcacc ttcacggtta tacgcttcac acgggctgcc gatatgatcg
    18121 gtaaggatgg tgaactggtc cgtagcagta agtttggcgg cagggcacat ggcaccttcg
    18181 tcaaacaccc aggtgacaag gctttccggc ggcaccggtt ccggccggtc catcaccagc
    18241 tccccatatt cgttcactgc cgttacgggt ttttcggcta atgggtagga ccattcatgc
    18301 agtagtttgt tggtatccca aacatagcgg gtaacgcggc cattgaagat tttttcggtc
    18361 ctgcgggcca gcgcgtcata gcggaaagat accgttttct ggtccggtcg cagcaccgat
    18421 ttcagcatgc cattggcata ccattcgtac tcccatattt ccggtgtggt ccctgtggtc
    18481 acaatttttt tccgcaggta tccctcgtca ttatacagga agcgggctgt atctgtttcc
    18541 agcaggcggc ctccttcgcc gtatttgcga tctttacgcg tttgtgtttt atagagattc
    18601 cctcccttgt cgggcaaacg gtaatcgtag ctgccatctt catactgcgc ccatgccagc
    18661 tggctccatt catcgtatcc gtagttgatg gtaccccgtg tgagcgcatt ggtcgcctgc
    18721 cgcagccgtt ggttggcatc ccagtggtag agccggtggc gggtggtcct gccgttgctg
    18781 tatacctggt gtccgtccgg cgtaccggcg gcagaagaac cgggaaggta gttccagctg
    18841 ctttttacgc cgcccggcaa cgtacgttct atctccagcc ccaacaggtt gcgctgaatg
    18901 tgggcagtcc aggggtcctg ctctcctgtg gcggcagtga tgccggtcag cgcactgaag
    18961 ctgtcccact gcatcttaat atccgcgccc agtctgcttt tcatggccgt tcgtttacca
    19021 tcggaattat accggctgtt gatcacataa ccgtcctgcc attctgtgag gatattaccc
    19081 gcgccatctc tttcaaaccg cacctggctg tggttgttgg ctgcttctat gatctggccg
    19141 ttgcggttat agttaaatgt ttcaaagctg ccgtcattcc attccacgcg ggaaaggtcc
    19201 ccgttagtac tgtattcgaa atgggtccac tggttgccgg gacggtgtac acggataacg
    19261 cgcccggtcc cgtcgcgctc aaaatgccgt accagtccgt cgaaccccgt ctccgaagcg
    19321 atctggcctg ctgcgttgcg aacgaagcgg taagtctccc ccagcgggtt tacgatggcg
    19381 gtcagctgct cgtccgtatt atagacataa tgtgttttcc tgccgttttc atcccgtttt
    19441 ttcaggcttc ccagcgcggt gtattcgtaa cgtatctcat gttgtttgtc cttcgccgcc
    19501 actacttcgc cgtaggcgtt atattccagc tgaatatggt tgccgtcggg caaccatata
    19561 tcggtagtgc ggcccagcag gtcataccgg aactgctgct cttcccggaa aggattagtc
    19621 accttcaggc actgccccca ggcgtcgtaa cgccattcac tgtgggtgcc gtctgccatg
    19681 gtaacgcttt gtacgttgta atcttcatca taggcaatgg cggtgtaact gtcattttct
    19741 tcttccacac gacttatcag ctgatgttcg ttgtaccggt aaatccgtat gcggccgtct
    19801 ccttccgtga tggtatggag caatccggag ccggcgtagt agataaacgt acggctgttt
    19861 ccctccgcat cggttacgct gatgagcctt ccctgctcat cgtagatagc gcttgtttca
    19921 ctgccatccg gctttaccat accagtttta ttccctcttt catcgtacgt gtaaccggta
    19981 acgttacctt cggcatctat tacccggtaa atctccatat cggccgtata gtcatagaaa
    20041 acggaattgc cgagcggatt tttcacctgg tgcaccacga agtccggtgt atagtagtaa
    20101 gtggtcgtat ggccctgcgc gttggtcact tcattataac cttctttggg atgataggca
    20161 atgaaacctt ccatcacgcc accgtcaccg taagcatgta tgcagcggcg ctgcttgtcg
    20221 tattcccaat agaaagacac cccgtcacgg cccgtctttt ttaccatcag gtggtcttcg
    20281 taggcgatat ccgtcgtctg gtcgagggcg tctgtcaccg ccaccaggtc accttcttcg
    20341 ctgtaggcgt attgcaccag tgtcttttcc tctccccgat ggcggccggc gacacggagg
    20401 atgcgtccat gaggatcgct ggtgatcagc agatggcggc cggcgctgtc tgtcacgcgc
    20461 agcaggtgcc ccaacgcatt ataatggaag gtgaccagga agtctgattc cgtactgatg
    20521 ctcatcagcc ggtattgttc atcctgcgga tgtaccttgc ggaaaataca ggtgtaacgg
    20581 ttctcctgct gaaagagcgt aaattcatca tgataggtgc gggtaagttg cagtttctca
    20641 tgccggttgt agtcggtgtt gccggtaaaa ggcagcgcat caaataccgc ggtgcggcca
    20701 tctcccagta ataccgctgt aacgccttcc tgtggcagct cttccagccg catatcatat
    20761 ttgagatgat tgccgcggcc cagcagccct tcaaaagcac tgtcgctgtt ccaggaccgc
    20821 gcccatttga gtggaacagg cccgggcaat tcaaagtcgg tataatcgta gataacgatg
    20881 ccctgcacca ggtctaccgg ctccagtcct tttttacaga gcatgctgct cagttt
//
