LOCUS       NZ_FUWZ01000001        20975 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000001
VERSION     NZ_FUWZ01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2044058
            Orig. end                         :: 2065033
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10975
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1269..2417
                     /locus_tag="B5D63_RS08470"
                     /old_locus_tag="SAMN04488128_1011688"
     CDS             1269..2417
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012744.5"
                     /locus_tag="B5D63_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011688"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_078668273.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.9e-36,
                     bitscore: 122.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKLLVHAWVVHREGGKYYLPYTHWVYLKEIVKYYEEVCLMSPVQ
                     QHTDKSPKSLMDIGCFDNVKVYALPYSPNYVRAVPHFPAYLKAYRKLKHYDEVYARYPV
                     PFGWLGKFFFKGKKRIVHFVGDPVDAARTNPNFSRLKKFTMITLFMPEHSAYMWACKGA
                     SVFTNGHHLRDKLTGWGIQAKAVISSTLNDADFYPKEINGISEEGPKLLYVGYLRKAKG
                     VETVIRSFQIVQRKYPGSRLTVVGSGEFERELKDLAAVLHLDGHIHFAGHVDNREELNN
                     YLRSHDIFCFASLSEGSPRVILEAMANSLTVVSTPVGSLPNVFEDKQDILFADFNDHEA
                     FYHRVDTLVKDNTLRRQLSDNAYRKVRGFTIEGFIKSIFNEG"
     misc_feature    complement(1279..1292)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            2407..2916
                     /locus_tag="B5D63_RS08475"
                     /old_locus_tag="SAMN04488128_1011689"
     CDS             2407..2916
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_1011689"
                     /product="acyltransferase"
                     /protein_id="WP_078668274.1"
                     /transl_table=11
                     /translation="MKVKISILYSWLVKMITFLLPNIPVCMRFRGFLYSLMMKGCGRNF
                     QVTSTAVLNSLAGLEVGDNVYIAHHTVLIGIDIAIGNEVIIGPNCIISSGNHTFLNNSY
                     RYGKSLRRPVKIGAGSWIAGNCSVLGGSILPERSVLGAGAVLNKKYDTADGLYGGIPAV
                     FIKKMR"
     gene            2946..4136
                     /locus_tag="B5D63_RS08480"
                     /old_locus_tag="SAMN04488128_1011690"
     CDS             2946..4136
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024968.5"
                     /locus_tag="B5D63_RS08480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011690"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_159455941.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.6e-09,
                     bitscore: 32.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSSGGTRSYDLATRFAKAGHKVVVVTTSSFLKQYTFTDTWTVM
                     EVDGVELHVLNLEYSNKMSFAKRALTFVQFVAKSTMRVLKLQGDVVLATSTPITIAVPA
                     MIKRTLHKVPYIFEVRDVWPEVPVAMGIINNKLLVSLLNRFEKRIYRRAAHIVPLSDDM
                     KRSIEERTAVPVKKLSVIPNISEVVRFGKYDTGKSILSGLLGFTPEKTVLYAGTLGMVN
                     GLRYLADLAAHMLRLDDSVKFVVFGDGMEKAALLKYAEEKGVLGNNLFFFDPVPKSQLS
                     QLYYECTIASSFVIPVPELWANSANKFFDCLAAGRPILINHRGWQANVIEQENVGFVMH
                     YDTADMPVEARRFAEYINDKPLLQQQQAKALLLAQQRYSLDIAAGAYLKILDHVVS"
     gene            4123..4737
                     /locus_tag="B5D63_RS08485"
                     /old_locus_tag="SAMN04488128_1011691"
     CDS             4123..4737
                     /EC_number="2.7.8.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606174.1"
                     /locus_tag="B5D63_RS08485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011691"
                     /product="sugar transferase"
                     /protein_id="WP_317044762.1"
                     /sec_met_domain="Bac_transf (E-value: 9.3e-64, bitscore:
                     211.0, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYRSFLKRWLDMLVAFTALLLLSPVFIVVTVLLFIANSGKPFFL
                     QPRPGLKGRVFRVIKYKTMNDKKAPDGNLLPDEARLTAVGKFVRKTSLDEIPQLINVLK
                     GDMSLIGPRPLLVDYLELYSPQQARRHEVRPGITGWAQVNGRNAISWTQKFERDVWYVD
                     HLSFQLDVKILFMTVIKVFKSEGISQAGHVSSERFTGKANA"
     gene            4766..5896
                     /locus_tag="B5D63_RS08490"
                     /old_locus_tag="SAMN04488128_1011692"
     CDS             4766..5896
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014221483.1"
                     /locus_tag="B5D63_RS08490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011692"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_078668276.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7e-95, bitscore:
                     315.1, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.5e-07, bitscore:
                     25.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIWLSSPHMGGTEQSFVTTAFETNWIAPLGTNVDGFEQDLEQ
                     FLKEGDVAALSSGTAALHLALIQSGVSAGDEVICQSMTFSASANPIAYQGAIPVFVDSE
                     RDTWNMDPVLLEQAIKERIAKGKKPKAIIPVHLYGMPAKMNEILAVAAEYEIPVIEDAA
                     EALGSWYHDKACGTFGDFGVLSFNGNKIITTSGGGALVGKDKAAIAKSRFLASQARDPA
                     PHYEHTHIGYNYRMSNICAGIGRGQMEVLGKRVEQRRSNYQHYLRTLSDLPGVSFVAEP
                     AGSFSNRWLSTVLIDPAQSNGITRETIRLALEKHIIESRPLWKPMHLQPVFASAPAYVN
                     GVSEALFENGLCLPSGSNLTQAQLQQTTDIIRSLWK"
     misc_feature    complement(6022..6035)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.84"
                     /tool="antismash"
     misc_feature    complement(6029..6042)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.39"
                     /tool="antismash"
     misc_feature    6030..6043
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.42"
                     /tool="antismash"
     misc_feature    6039..6052
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.28"
                     /tool="antismash"
     gene            6125..7693
                     /locus_tag="B5D63_RS08495"
                     /old_locus_tag="SAMN04488128_1011693"
     CDS             6125..7693
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04131.1"
                     /locus_tag="B5D63_RS08495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011693"
                     /product="gliding motility-associated C-terminal
                     domain-containing protein"
                     /protein_id="WP_143312815.1"
                     /transl_table=11
                     /translation="MQYCSMKIVFNICRGIYATAVAALAICISFSLSAQDIEIKNPSLE
                     GPPRAAAAPPGWAIINNSPDLLPGCCAVSKPPSDGNTYSGMISNATMEEGIYQKLSASI
                     KGGKAYAFSADLAHPSVYFGQKTCLGGFVVYAANAPGAKEEVLWKSPAFDHADWKRYRI
                     EFTPTKDYAYIMLCNYFIPCRDGKLGAVLVDNLSPYLQEIPRITVTVTPTCKGTSMGIA
                     RVDVLSGPSPFTCKWLPGGQTDNFVDHLAAGSYEVTVTGANGTYATAIARIDAVELQNK
                     ITVTPSKCYGDNTNVLSLVTTGGKPPYRYYLNGSDHPQYTPEFRDLRPGNYRLLAKDEM
                     GCVSPEEKIAVAEPAPLQLMSAQVKDISCSETHDGQITLTLAGGTVPYHYRLETGEWQS
                     DSAWRKLDEGRYYFIAKDNNDCQVRGAVEIIRNNRQCAVYVPTAFSPNGDGRNDLFRCR
                     VNDDISKYQLQVFNRWGTLVFQSNDPGQAWDGYRQPAGSYVWVLVYTDSKLQGRRQQGS
                     LVLVR"
     gene            complement(7690..8439)
                     /locus_tag="B5D63_RS08500"
                     /old_locus_tag="SAMN04488128_1011694"
     CDS             complement(7690..8439)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039343.4"
                     /locus_tag="B5D63_RS08500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011694"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_078668278.1"
                     /transl_table=11
                     /translation="MFFFRKKRDDSKLLAPFLSGVETDIHSHLIPGVDDGVPDVDTSVA
                     FISQLHELGIRKIITTPHIMMDRYPNSQDTLHGPYLEVEAALAARQINVPFNYAAEYYM
                     DEQFENLLKSPLLTLNGRLVLVEISFVSAPPQMHHWLFQLSARGYMPLLAHPERYNYCH
                     KNFQQYKEFKSWGCQLQMNLLSLTGYYGKHVQQAATQLLDANMIDYIGTDLHHAKHMQA
                     IREIAQNKKLLKRLEQYPFKNNKLTTG"
     gene            complement(8500..8973)
                     /locus_tag="B5D63_RS08505"
                     /old_locus_tag="SAMN04488128_1011695"
     CDS             complement(8500..8973)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014222474.1"
                     /locus_tag="B5D63_RS08505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011695"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_078668279.1"
                     /transl_table=11
                     /translation="MAEDLQIIQGEKAEQYQSLIPQIKGLLEGEPDLVANLANVAAALK
                     EQFGWFWVGFYLVKQEELVLGPFQGPVACTRIRKGRGVCGTSWAQATTLVVPDVEAFPG
                     HIACSSLSKSEIVVPLMKDGVVAGVLDVDSELPDHFDTTDQQYLEEIVKLIVL"
     misc_feature    9050..9065
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.96"
                     /tool="antismash"
     gene            9290..9829
                     /gene="idi"
                     /locus_tag="B5D63_RS08510"
                     /old_locus_tag="SAMN04488128_1011696"
     CDS             9290..9829
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012792335.1"
                     /locus_tag="B5D63_RS08510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011696"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_078668280.1"
                     /transl_table=11
                     /translation="MNQPEVILVTESDEAIGTMEKMEAHRRGLLHRAFSVFILNDAGDM
                     LLQQRALGKYHSPGLWTNACCSHPLPGETIPEAAHRRLMEEMGFDCPLEEIFSFTYRTA
                     FDNGLIEHEFDHVLIGTHNGAIHPDSTEVNDYRYMSVHQILELMEKEPARFTSWFHLAL
                     PRVLKHLNMSVTAAGI"
     gene            10001..10975
                     /locus_tag="B5D63_RS08515"
                     /old_locus_tag="SAMN04488128_1011697"
     CDS             10001..10975
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="B5D63_RS08515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011697"
                     /product="hypothetical protein"
                     /protein_id="WP_078668281.1"
                     /sec_met_domain="T1TS (E-value: 2.2e-95, bitscore: 317.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTIQFPRIQYPFPSRLNSHVAAAQQHVEDWVHHHGLLSTDKARA
                     RFAKARFAWLAARAFPDAGLHELCIIADFNTWLFILDDQCDEAEAGKKSGFLRSVMTGF
                     MDIFRLPDPRSPANNAPLPAALISIWERMKAISTPAWQERFIRSMEDYFNSCLWEAQNR
                     ENRIVPTVADYVRMRPYTGALLADVEAIDIIEKIYLPADTLQNALLKRMVQACNNIVCW
                     ANDLFSFPKEHQAGDVHNLVLVLQHEHQCSLQEAIDEAARMHNEEVAIFVVLEKLLPLT
                     GNEKDYELLRYVAVLRSWITGNFDWSMHDTGRYSAMMKEYVNS"
     gene            complement(11011..12054)
                     /locus_tag="B5D63_RS08520"
                     /old_locus_tag="SAMN04488128_1011698"
     CDS             complement(11011..12054)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS08520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_1011698"
                     /product="hypothetical protein"
                     /protein_id="WP_078668282.1"
                     /transl_table=11
                     /translation="MMEVDKRDGQFLHRAIRQWQQDQLITDVQAEALQKSYSVRSNDWQ
                     TITLYIFIAAISCALMAFGSLVLDEKWIEVLRKKFSLTDGVIAFLFAGLTAFLCYQGWR
                     RNRHQPAFSFNRELFWLLPVLSTGVTVVYLGKSMDYLGGNYGVFWLLATAVYATVALTL
                     HSRLLWMATLICLIPAYVKLTYYLTGDGPYFLGMNLPCRMALLAAVIIGAGWLMKRSAI
                     FLPAKEITWGGGWLLFLLSGWLISIFGNCGTWEEWQALRQVHLLWWVVVFSVQCILTLL
                     LGIRTKDDLLRDLGVIFLLLDLYTRYFEYLWDRTNKGLFFSILAVSFWWLGKRLEKYIS
                     KRKGTPG"
     gene            complement(12059..12769)
                     /locus_tag="B5D63_RS08525"
                     /old_locus_tag="SAMN04488128_1011699"
     CDS             complement(12059..12769)
                     /GO_process="GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018446.5"
                     /locus_tag="B5D63_RS08525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011699"
                     /product="TMEM175 family protein"
                     /protein_id="WP_078668283.1"
                     /transl_table=11
                     /translation="MSMSVIKEAKTPHREFELDRAVLFSDAVFAIAITLLIIEIKLPHM
                     PEHLPAGGYRQVLHPFLMEFFTFAMSFMFIGTFWKWHLHLCRFLQHYDDGLIHRNLFFL
                     FFIVTFPFSTASMMHMSSHFMLPLYIYLFNLAGCLAGLFWISYYIFQRKPGLAVVGQHT
                     EKELLYQRLKYSFLTMTFGFTAIALAYFIYPDNQTIQNISFCLIPLLIFFNHFRLKIKK
                     RNTLRLVHIGDKSS"
     misc_feature    12827..12836
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.86"
                     /tool="antismash"
     gene            13072..14349
                     /locus_tag="B5D63_RS08530"
                     /old_locus_tag="SAMN04488128_1011700"
     CDS             13072..14349
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF014385.5"
                     /locus_tag="B5D63_RS08530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011700"
                     /product="TolC family protein"
                     /protein_id="WP_159455942.1"
                     /transl_table=11
                     /translation="MDTTRGNYAFNLADCIQYGIAHHHDMVNANLDVDFSREQVKEATA
                     KLLPHADINANFTDNMKLATSLIPDIASGNYDRKIPVQFGTRFASNATGQINQTIFQSD
                     YFLGLKASRVYRGLATKNLTRTEIDTKVAIIKAYYAVLTNQENIRLSKSNLDQLRKTLS
                     DTKARYDAGVSERVDVDRIQVSYNNGVTRIENQIRELVYTMQLLKFQMGMPQESDLELR
                     ETVQDLNVEAFSTDTLNYKVEDRVEYSIQNTQIALNELNLKSKKMAYLPQLNFFVNYGV
                     NWFSTKFGDLYKQGFGASALGLNLSWSIFTGTERLHQIRQLGITLKKSQNDLDFLSQQI
                     KLEVKSANTSYESNRATFVTQKTNMTLTQGIYDRIVLKFEQGVATSLDVISAESQLTQA
                     RTDYVNAMLATLISKTDLDKAMGRIK"
     gene            14389..15531
                     /locus_tag="B5D63_RS08535"
                     /old_locus_tag="SAMN04488128_1011701"
     CDS             14389..15531
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0042802 - identical protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /locus_tag="B5D63_RS08535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011701"
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_078668285.1"
                     /transl_table=11
                     /translation="MYLKSNWIIILVALLGTACGGGKKQQQQAAMMGMMKATVVAQEVV
                     PASYTVHTQFPATLTAHDEVAIRSDVTGYLSAIKVKDGSMVKKGQPLYEIDKSRYVAAY
                     GQVAATQQQAEADLAQKEKDYERYKTLLEHDAISKQTVDQAYTAVMTSKANLAAAKAAV
                     ARAGTDVNHAIIRAPVSGSIGIVQIKVGDIVNAGQTLINTLVNEHPIFADFDVPQASIP
                     QFYRIQKGQGDEKFFLKFTSGETYSEQGKIQAINNIVDPQTGTIRVRLVFGNKDGQLKS
                     GMSGVVVMQYATPATQVAIPAKAIVQNLSETSVMTLTKDNVVKPVHITPGPVTDTMLIV
                     EDGLKAGDRIIVEGLQKVRPGDTVNVAGPGTPAAPPAGKH"
     gene            15554..18727
                     /locus_tag="B5D63_RS08540"
                     /old_locus_tag="SAMN04488128_1011702"
     CDS             15554..18727
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) RND_efflux"
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014220223.1"
                     /locus_tag="B5D63_RS08540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011702"
                     /product="efflux RND transporter permease subunit"
                     /protein_id="WP_078668286.1"
                     /transl_table=11
                     /translation="MISKTFIERKNTTIVISIILVIVGLICMFNLPIAQLPDIAPPVTD
                     VRANYVGANSTTVEETVTTPIENQVNGTPGAMYIQSVSANDGSMSITVTFNLGTDPDIA
                     TLDVQNRVSLALPSTPDEVRRVGVTVKKRSNDMLMVIGLNSPKGQHTREFLDNYINIYL
                     KPELARIEGVGDVNAFSQDYSMRIWLNPDKMAALNLTAADIARAVTEQNQQVPAGSIGA
                     PPMSRTQAFEYTVSVRGRLATSEEFGNVVVAKNPNGGLIRLRDVARINLGSFTYAIDAK
                     ADGKTGSGLAIYLAPGANALDVNDRVIAKMEELAKSFPEDVNWLIPFETTSFVKISINE
                     VFHTFLEALALVVIVVFIFLQNWRATIIPILVIPISLIGTFIFFQLLGFSINTLTLFGF
                     VLAIGIVVDDAIVVVEAVQHHIDADLMSPREATFKAMSEVQAPVIAIALILAAVFVPVA
                     FIPGVSGRLYQQFALTIAFSVLLSAFLALTLTPALTAILLRPAHLTKKSHGLNKFFYKF
                     NEWFTRVTNRYGNMVMRSIRFTPVVLILLGVLFAVAFYLFKKTPTTFVPQEDMGALFIA
                     LELPEAASTERTKQVVDEIGHILSADSAVNHFFGITGMNFVANAVKPNSGTFFVSLKPW
                     DERYAHGDDIGKVLGRIQGAASRIVGATIIAIPAPTLRGMGTSGGFSFILEQKSNPDIK
                     QFMQVMGQFLMEANQRPEIARAYAFFSANTPQFNVEVDRDKCKQLGVAVSDVFNALQTF
                     LGGLYVNDFTRFSRSFRVVMQADSLYRTSIDNLATYYVRNNLGQMVPLSALITTKKGAG
                     APVINHFNLYRSVEIDGDSQVGYSSGDAIKALQEVAAKVLPENFGYEWANVSLQEIKAG
                     NSSVLIFMLSILFVFLLLTALYESWSVPFSVLLAVPVALFGSIVALALTKQANSVYSQI
                     GLITLIGLAAKNAILIVEFCKERVDRGMPLMEATLEAVKLRFRPILMTSFAFILGVVPL
                     CLAQGAGAASRVNIGYTVIGGMLAATVLGVFTVPVLYVLITKLAYGKKKLAELEAHGNE
                     EKKPKGLGE"
     gene            18742..19500
                     /locus_tag="B5D63_RS08545"
                     /old_locus_tag="SAMN04488128_1011703"
     CDS             18742..19500
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="B5D63_RS08545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011703"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_078668287.1"
                     /transl_table=11
                     /translation="MKNTERFSNRVTDYEKYRPHYPVAIIPYLSATTGLSHSSVIADIG
                     SGTGLSAQPFLDNGNTVYAVEPNEAMRASAEQHLGRFPGFKSVAATAEHTSLPNHSVDL
                     IVAGQAFHWFDQELTRKEFHRIAKPDAYAALMWNLRSVSTPFEQDYEQLLQEHGVDYKH
                     MQQRHVGPMQLAAFFLPGTFKEKTFQNAQRFDFKALKGLLSSSSYMPARSHENYPAMIK
                     DLEDIFHKYQEQGMVTFKYETKLYTGRLSE"
     misc_feature    19505..19518
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.45"
                     /tool="antismash"
ORIGIN
        1 gaccatatcc aaaaccggcg ccctgttcag cagcctttct gtatttgtca tgtcctgcat
       61 ggcacagggc ggtgatctcg attataacgg gaaaaaattt gtttttacca gcgttcctgc
      121 tcaatataat gttgccgctt cttctgccgt taaagcgaag gtaaatgccg gcattcaatc
      181 ggccactgac ctgacgacgt tgttgcctgc cggttataaa aaggatggct cggtggacta
      241 tactgattat ctgcaacgcg gcctcgacaa aaacaggaac gtcgtgtttc ccgattttcc
      301 ggtgctgatc agcagcaaag ggctgacagt cagcagtaac tcgaacctgt attttaagcc
      361 cgattccaaa ctgatcatgc aacccaataa cctcgaccgg tttgaaatgt tacgggtcca
      421 cggcgtcagc aatgtcaata tctacaatgc gaacctcgtg ggcgaccgca aaggccacct
      481 gggcaccacc ggcgagcatg gtgtcggtat tgcgctgcgt tcagccaaag acgttaatat
      541 ctacagtccc cgtatctcca gctgctgggg agatggcatc tacatcggct ggcgtacccg
      601 cgacgtggtg gatggccatt acattcccag cgataacatc aatatctaca acggtgtcat
      661 tgattttaac cgcagaaacg gcatctctat cgtatgcggc cgcaatatca atatccggaa
      721 taccactatt gccaatactt acggcacctt gccgatgagt ggcattgata tcgagcccaa
      781 tgaaccaaag gatattatca ataatatcac catcgacagt gtcacgactt acaataacgc
      841 ccgggacggt atcctgatcg tactaacaag gttaccgaaa aacaacggca acgccactac
      901 gaacattgtg gtgaaaaatc atgtggacga cggctcctac agcgccttcc ggctagggtc
      961 cggtttccgg aaaaccgacc gggaaatgac ggggcagatt tccgtgatag atccggtatg
     1021 gaaaaacaat gaaaaaccct tccgtttccg gagcaattac cagatgctgc cggtcacgaa
     1081 gtttaaaaat atcaaagtca tgggcggtcc tgccggcgcg ggcggaaagg cggcgcgtaa
     1141 cgctgtgcaa agtttcagcg cgccggtgca gaatgccggc caggatgcgg taaaaaaaat
     1201 cagggctggc ttaagtaaag aaagtaaaat caggatagaa gacaaataaa ccacgaatca
     1261 acattattat ggcaaaattg cttgtacatg catgggtggt gcacagggaa gggggaaagt
     1321 attatttgcc ctatacgcac tgggtgtatc tgaaagagat tgtaaaatac tatgaagagg
     1381 tatgcctgat gtcgccggtg cagcagcata cagacaaaag tcctaagagc ctgatggaca
     1441 ttggctgttt tgataacgta aaagtatatg cgttaccgta ttcgcccaac tatgtgaggg
     1501 cggtaccgca tttcccggct tatctcaagg cctatcgcaa actcaaacac tatgatgaag
     1561 tatacgcccg ttatccggtg cccttcggat ggctgggtaa atttttcttt aaagggaaaa
     1621 aaaggatcgt gcatttcgtg ggcgacccgg tagacgctgc caggaccaac cccaacttca
     1681 gccggttgaa aaagtttacc atgatcaccc ttttcatgcc agaacattca gcctatatgt
     1741 gggcttgcaa aggagcatcg gtatttacca atggtcatca tctcagggat aaactgaccg
     1801 gctggggcat tcaggcgaaa gctgttattt cttccaccct caacgatgcg gatttctatc
     1861 cgaaggaaat caacggcatc agcgaagaag gacctaagct gctgtatgtg ggatacctgc
     1921 gtaaagcgaa aggtgtggag acagttatcc gttcttttca gatcgtgcaa cggaaatatc
     1981 ccggctcccg cctgacggtg gtcggctccg gcgagttcga acgcgaactg aaagacctcg
     2041 ccgccgtatt gcaccttgac gggcatattc actttgccgg tcacgtcgat aaccgggaag
     2101 aactgaacaa ctatctgcgc tctcatgaca ttttctgctt cgccagtttg tcagaagggt
     2161 cgccccgcgt gatcctcgag gccatggcca acagcctcac ggtggttagc acccccgtag
     2221 gctccctgcc caatgtgttt gaggataaac aggacatcct gtttgcagat tttaacgatc
     2281 acgaagcttt ttaccaccgc gtagacacgc tggtgaaaga taacacatta agacggcaac
     2341 tgagtgacaa cgcctaccgc aaagtaagag gattcaccat agaaggattt attaaaagca
     2401 ttttcaatga aggttaaaat ttctatccta tactcctggc tggtgaagat gattaccttc
     2461 ctgctgccta acatacctgt atgcatgcgt ttcaggggat tcctgtattc gctgatgatg
     2521 aaggggtgcg gccgcaattt ccaggtaacg tctacggctg tactgaattc cctcgccgga
     2581 ctggaagtgg gcgataacgt ttatatcgcg catcataccg tattgatcgg tatcgatatt
     2641 gccatcggca atgaagtgat cattggtccc aattgtatta tctcttccgg caaccatacc
     2701 tttttaaata actcttaccg ttatggtaaa tccctgcggc ggccggtgaa aatcggcgcc
     2761 ggttcctgga ttgcgggcaa ctgctccgtg ctgggcggca gcatactgcc ggagcgctct
     2821 gtgttgggcg ccggtgcagt actcaataaa aaatacgata cggcagatgg tttgtatggc
     2881 ggcattcctg cagtattcat aaaaaaaatg cgatgaggat actttatata catcaatatt
     2941 ttgccatgcc aacctcctca ggaggtaccc gttcctatga tctggccacc cggttcgcca
     3001 aagccgggca taaagtagtg gtagtcacca ccagctcctt tctgaaacag tatacgttca
     3061 ctgatacatg gacggtgatg gaggtggatg gggtggagct gcatgtgctc aacctggagt
     3121 acagcaacaa aatgagtttc gccaaaagag cgctgacctt cgtgcagttt gtggcaaagt
     3181 ccaccatgcg ggtattaaaa ctacaggggg atgtagtgct ggctaccagc acgcccatta
     3241 ccattgcggt acctgccatg attaaacgca ccctgcataa ggtgccctat atttttgaag
     3301 tgcgtgatgt gtggcccgag gtgcccgtcg ctatgggcat tatcaataat aaattactgg
     3361 taagcctgtt gaaccgcttc gaaaaacgca tctatagaag agcggcgcat atcgtaccgc
     3421 tgtcggatga catgaagcgc tccatcgaag agcgtacggc cgtccccgtg aagaagctgt
     3481 ctgtcatccc caacatatcg gaagtagtgc ggttcggcaa gtacgatacc ggcaaaagta
     3541 tcctgagcgg gctgctcggg tttacgccgg agaagacagt gctctacgca ggcacgctgg
     3601 ggatggtgaa cgggctgcgt tacctggcag acctggcggc acacatgctg cgcctggatg
     3661 acagcgtaaa gtttgtcgtt ttcggcgatg gcatggagaa agcagcactg ttaaaatacg
     3721 cggaagaaaa gggggtactg ggcaacaacc tgtttttctt tgaccccgta cctaaatcac
     3781 agctgtcaca attgtattac gaatgtacca ttgccagttc gtttgtaata ccggtgccgg
     3841 agctgtgggc caattcggcc aacaagtttt ttgactgtct tgctgccggc aggcctatcc
     3901 tgattaacca ccggggctgg caggccaatg tgatagagca ggagaacgta ggatttgtga
     3961 tgcattacga tacggccgat atgcccgtag aggcaaggcg gtttgctgaa tatatcaatg
     4021 ataagccgct gttgcaacag cagcaggcaa aagcgctgtt gctggcgcag caacgttatt
     4081 cgctggacat tgccgcaggc gcttacctta aaattctcga ccatgttgta tcgtagtttt
     4141 ctgaaacgct ggctggacat gctggtagct tttaccgcac tgttgctgtt gtcgccggta
     4201 tttatcgtgg taacggtcct gttgtttatt gccaacagtg gaaaaccgtt cttcctgcag
     4261 ccgcgtcctg gccttaaggg ccgggtgttc cgggtgatta agtataaaac gatgaatgat
     4321 aaaaaggcgc ctgacggcaa tctgttgccc gatgaagcgc gattgaccgc tgtgggtaag
     4381 ttcgtccgca aaacatcgct cgatgaaatt cctcagctga tcaacgtgct caagggagat
     4441 atgagcctca ttggtccgcg tccgctgctg gtagattacc tggaactgta ttcgccgcaa
     4501 caggcccggc gtcatgaagt aagaccgggt attacaggct gggcacaggt gaacggtcgt
     4561 aatgccatca gctggacaca gaagtttgaa cgggatgtgt ggtatgtgga ccacctgagc
     4621 tttcagctcg atgtaaaaat cctgttcatg accgttatca aagtatttaa atcagaaggt
     4681 atttcacagg caggacatgt atcgtcggag cggttcaccg gaaaagcgaa tgcctgaatt
     4741 ttaactatat taaatattgt caactatgag cgaaaagatt tggctctctt ccccccatat
     4801 gggcggcacc gaacaaagtt ttgttaccac tgcttttgaa accaactgga ttgccccgct
     4861 gggaactaat gtggacggct ttgaacagga tctggaacaa tttctgaaag agggagatgt
     4921 ggctgcgtta tcttccggta ctgccgcact tcacctcgcg ctgatacagt ccggtgtgag
     4981 cgcaggcgat gaagtgattt gccaaagcat gactttctcc gcttctgcca atcccatcgc
     5041 ttatcagggc gctattccgg tgtttgtaga cagtgaaagg gatacctgga acatggaccc
     5101 ggtgttgctg gagcaggcca tcaaagagcg catcgccaaa ggcaaaaagc ccaaagcgat
     5161 catcccggtg catctgtacg gtatgccagc taaaatgaat gagatactgg cagtagccgc
     5221 agaatatgag atcccggtga tagaagatgc tgcagaagca ctgggctcct ggtatcatga
     5281 caaagcctgc ggtacgtttg gtgatttcgg agtgctgagt ttcaacggta ataagattat
     5341 taccaccagt ggtggaggtg cgctcgtcgg gaaagacaag gcggctatcg ctaagtcccg
     5401 ctttctcgcc agccaggccc gggacccggc gccacattat gaacataccc acatcggtta
     5461 caattaccgc atgagtaata tatgtgcggg cattggccgg ggccagatgg aggtgctggg
     5521 caaaagagtg gagcaacgca gaagtaatta tcagcattac ctccgtacat taagcgatct
     5581 gccgggggta agctttgtag cggaacctgc cggttctttc agtaaccgct ggctgagcac
     5641 cgtcctgatc gatccggcgc aaagcaatgg cattacccgt gaaaccatac gcctggcgct
     5701 ggagaaacat atcatcgaat ccagaccgct gtggaagccg atgcacctgc aacctgtttt
     5761 tgcttctgca cccgcttacg tcaacggggt gtctgaagca ctcttcgaaa acggattatg
     5821 tctgcccagc ggctctaacc tgacgcaggc gcaactgcag cagaccacgg acattatccg
     5881 ctccctctgg aaataaattc cgatgttacc aaatatttaa aagttataac ggccccgcat
     5941 atacggggct ttttttcgtt tattatacgt gcttcttttt aattagtgat ccaaatcgtt
     6001 cgtcatgtat aataaattat tttttagttt aaaataaata taatttttat taatgagtat
     6061 atttgtgcga taatttcaac ttaaagggtt cgtcagtcgt tgttcgatta taaccatatc
     6121 ttttttgcag tactgttcta tgaagattgt ctttaacata tgcaggggca tctatgctac
     6181 agctgttgct gcgcttgcta tctgcatttc cttttccctc tccgctcagg acatcgaaat
     6241 taaaaaccct tcgctggaag ggccgccacg cgccgccgcc gcgccgccag gctgggctat
     6301 tatcaacaat tcaccggatc ttctgccggg gtgttgtgcc gttagcaagc cgccatctga
     6361 tggcaacacc tacagcggta tgatcagtaa cgctaccatg gaagaaggta tttaccagaa
     6421 actatcggcc agcatcaaag gtggaaaagc gtatgccttc tcggctgacc tggcgcatcc
     6481 ttccgtttac ttcgggcaaa aaacctgcct cggcggcttc gttgtatacg ccgccaacgc
     6541 tccgggtgcg aaagaagagg tgctgtggaa atcgccggca tttgatcatg ccgactggaa
     6601 gcggtaccgg attgagttta cccccacaaa ggactatgcc tacattatgt tatgcaatta
     6661 ttttattccc tgcagagatg gaaaactggg agccgtgctg gtagataatc tctcccctta
     6721 tctgcaggaa attccccgta ttacggtaac ggttacaccc acctgtaaag gcaccagcat
     6781 gggcattgcc cgtgtagacg tgctctcggg accgtcgccg ttcacctgta aatggttgcc
     6841 cggtgggcaa acagacaatt ttgttgacca tctggctgcc ggcagctacg aggtaacggt
     6901 caccggcgcc aatgggacct acgctaccgc tattgcccgt attgacgcgg tggagctgca
     6961 gaataaaatc acggtaacgc cttctaaatg ttatggtgac aacaccaatg tcctatcgct
     7021 ggtcaccaca ggcggcaaac ctccttaccg gtattatttg aatggctccg atcatccgca
     7081 gtacacgccg gaattccgtg atctgcgtcc cggtaactac cggttgctgg caaaagatga
     7141 aatgggatgt gtttcgccgg aagaaaaaat tgctgtagca gagccggctc cgctacagct
     7201 gatgtctgca caggtaaagg acatcagttg cagtgaaaca cacgacgggc agataacgct
     7261 tacgctcgcg ggcggcactg taccatatca ttaccgtctg gaaacagggg agtggcagtc
     7321 ggacagcgcc tggcgaaaac tggatgaagg acgttattat tttattgcga aagacaacaa
     7381 cgattgtcag gtgagggggg ctgtggagat tatccgcaat aaccgccaat gcgcggtgta
     7441 cgtgcctaca gctttcagtc ccaatggcga cggccgtaat gacctgttcc gctgccgggt
     7501 gaacgacgat atcagtaagt accaattaca ggtcttcaat cgctggggaa cgctcgtttt
     7561 tcagagcaac gaccccggtc aggcctggga cggttaccgg cagcctgccg ggagttatgt
     7621 ttgggtgctg gtgtatactg acagcaaact gcaggggcgc aggcagcagg ggagcctggt
     7681 gctggtgcgt tagccggtgg tcagcttgtt gtttttaaac gggtactgct ccagccgttt
     7741 cagtaacttc ttgttttgtg caatttcccg gatggcctgc atgtgtttcg catgatgcag
     7801 gtcggtaccg atataatcga tcatattcgc gtccagcagt tgtgtggcgg cctgttgcac
     7861 atgtttgcca taataaccgg taagtgacag caggttcatt tgcagctgac atccccagga
     7921 cttaaattct ttatactgct ggaagttttt gtggcaatag ttgtaacgtt cgggatgggc
     7981 cagcagcggc atatatccgc gcgcgctgag ctggaacagc caatggtgca tctgtggcgg
     8041 cgcggatacg aaagaaatct ctaccagcac cagcctgccg ttgagtgtca gcaggggcga
     8101 cttgagcagg ttttcaaact gctcgtccat ataatattcc gccgcataat taaagggaac
     8161 gttgatctgc cgggcagcga gtgccgcttc cacctcgagg tacggtccgt ggagggtgtc
     8221 ctgtgaatta ggatacctgt ccatcataat atgaggcgtg gtaataattt tccggatacc
     8281 cagttcatga agttggctta taaatgctac gctggtgtct acatcgggaa cgccgtcatc
     8341 gacccccgga atcaggtgcg aatggatatc agtttcgacg cctgacagga agggtgccaa
     8401 caatttgcta tcatcccgct ttttcctgaa gaagaacatg gttaaatttt tcctttgatt
     8461 ttttcaggac aatggctcgc aaaatctttg ccatagtatt tataagacga tcagtttcac
     8521 aatttcttcc aggtactgct gatcggtggt gtcaaaatgg tcgggcagct cactgtccac
     8581 atcaagcacg cctgccacga cgccgtcttt catcaggggc accacgattt cagatttgga
     8641 aaggctgctg caggcaatat gtcccgggaa ggcttccacg tcgggcacaa ccagtgtagt
     8701 ggcttgcgcc cagctggtgc cgcacacgcc ccggccctta cggatacggg tacacgctac
     8761 aggtccctgg aacggtccca gtaccaactc ttcctgcttt accaggtaaa agcctaccca
     8821 aaaccacccg aactgttctt ttaacgccgc cgccacattg gccaggttgg ccaccaggtc
     8881 cggctcccct tccagtaatc cttttatctg cggaatgagg gactggtatt gttccgcttt
     8941 ttctccctga atgatctgca ggtcttctgc catttgtttt tgggtaaaga tacagcacgc
     9001 aaaggtgcaa agcagcaaag caaggggaga tttcgttttt tcgttttttt ttactttttt
     9061 ttgaccattc tactttcccc tggcaggatt aaatagctgg gtaggtatat ggtgatcatc
     9121 ccagcctttg cgtgctttgc tgctcagcgc ctttgcgaga tttttttact tttcccgtta
     9181 ttatcgtata tttaaactga ggtaaccatt gaggataaca gggctcatta tcagtaattc
     9241 gcgatcattt cagacagcta acagctttat taaatatctt tgctacacta tgaatcaacc
     9301 tgaagtaata ctagtgactg aatccgacga agctattggt accatggaaa aaatggaggc
     9361 gcatcgcagg ggcctgttgc accgcgcatt ttccgtattt attttaaatg atgccggaga
     9421 tatgctgctg cagcaaaggg cactgggaaa gtaccattct cccggcttgt ggaccaacgc
     9481 ctgctgtagc catccgcttc ccggtgaaac cattccggaa gccgcccacc gccggctgat
     9541 ggaagaaatg ggtttcgact gcccactgga ggagattttt tcttttactt acagaacagc
     9601 tttcgacaac ggccttatcg agcacgaatt tgatcatgtg ctgataggta ctcacaacgg
     9661 tgcaattcac cccgacagca cagaagtaaa tgactacagg tatatgtctg ttcatcagat
     9721 cctggaactg atggagaagg aaccggcccg cttcaccagt tggttccatc tcgcattacc
     9781 gagggtgcta aaacatctga atatgtctgt caccgctgca ggtatatagt caccctgtac
     9841 ttttttgtta catctcattt gctgttaacc gaagcaagcc aacttttact gtgccaacag
     9901 gtatggtggg ctgttaatat gcctgcccgc cgccgtttac cctggtttta cctatgccat
     9961 ttcataaccc ttaatagtta actgctaaat cctcagacac atgacaacga tccagtttcc
    10021 ccggatccag tatccgtttc cttcccgttt gaattcccat gtggcagcag cccagcaaca
    10081 tgttgaagac tgggtgcatc atcatggttt actgtccacc gacaaggcaa gggcccgctt
    10141 tgccaaagcc cgtttcgcct ggctggccgc ccgcgcgttc ccggacgcag ggctgcacga
    10201 gctctgcatc attgccgatt ttaacacctg gctgtttatc ctcgatgatc agtgcgatga
    10261 ggcggaagcc ggtaaaaaat ccggtttcct gcgtagtgtc atgacaggtt ttatggacat
    10321 ctttcgcctt cccgatcccc gttcaccggc caacaacgcg ccgctgccgg ccgcgctcat
    10381 cagcatctgg gaaaggatga aagccatcag cacgccggca tggcaggaac gtttcatccg
    10441 cagcatggaa gactatttta attcctgcct ctgggaagcg cagaaccgcg aaaatcgtat
    10501 agtccccacc gtggccgact acgtacgtat gcgcccctat accggcgccc tcctcgccga
    10561 cgtggaggcg atagacatca tcgaaaaaat ctatctgccg gcagacacgc tgcaaaacgc
    10621 actgctcaaa cgcatggtac aggcctgcaa caacatcgta tgctgggcca acgacctgtt
    10681 ttcttttccg aaagaacacc aggccggcga cgtccataac ctggtactgg tgctgcagca
    10741 tgaacaccag tgctctctcc aggaagcgat cgatgaagcc gcccggatgc acaacgagga
    10801 agtagccatt tttgtagtac tggaaaaact gctgccgctc acaggcaacg aaaaagatta
    10861 tgaactgctg cgctatgtag ctgtactgcg ttcctggatc accggcaatt tcgactggag
    10921 catgcacgat accggacgct atagcgccat gatgaaagaa tatgtcaaca gctgagataa
    10981 aaatattgga ccttcaggca gccccgggct ttagcccggg gtgcctttac gtttgctgat
    11041 gtatttctcc agccgcttgc ccagccacca gaaagaaaca gcgaggatag aaaaaaacaa
    11101 ccccttgttg gtccggtccc agaggtattc gaagtaacgg gtatacaggt ccagcagcag
    11161 gaaaataacg ccgaggtcac gcaacaggtc gtctttcgta cggatgccca gcaggagggt
    11221 gaggatacac tgtacgctga acaccaccac ccaccacaac aggtgtacct ggcgcagggc
    11281 ctgccattct tcccaggtgc cgcaattccc gaaaatagag atcagccagc cggacagcaa
    11341 aaacaacagc cagccgccac cccaggtgat ttctttggcc ggcaggaaga tggcggaccg
    11401 cttcatcagc cagccggcgc ctattatcac ggccgccagc aacgccatgc ggcaggggag
    11461 gttcatcccc aggaaatacg gaccgtcgcc ggtaagataa taggtcagct tcacgtacgc
    11521 gggtatcagg cagatcaggg tggccatcca caacagccgg gaatgcagcg tcagcgccac
    11581 ggtagcgtat accgccgtcg ccagcagcca gaatacccca tagttgccgc ccaggtaatc
    11641 catgctcttg ccaaggtaca ccacggtaac gcctgtactc aataccggta gcagccagaa
    11701 tagttcacgg ttaaaagaaa aggcaggctg atgccggttg cggcgccacc cctggtaaca
    11761 aagaaacgct gtcagcccgg caaacaggaa ggcgatcacg ccatccgtca gcgaaaactt
    11821 tttccgcagc acctcgatcc acttctcgtc cagcaccaac gacccgaaag ccatcagggc
    11881 acaggaaata gcagcgataa agatatacag ggtgatcgtc tgccagtcgt tgctgcggac
    11941 ggaatagctc ttctgcagcg cttccgcctg cacgtccgtg atcagctggt cctgctgcca
    12001 ctgccggatg gcccggtgca aaaactgtcc gtctcttttg tctacttcca tcataagctt
    12061 agctggattt atcgcctata tgtaccaggc gaagggtatt ccgttttttg atcttcaacc
    12121 ggaaatgatt gaagaaaatc aacaagggga tcaggcaaaa actgatattt tggatagtct
    12181 ggttgtcagg gtagataaaa taagcgaggg caatcgccgt aaaaccgaac gtcatcgtca
    12241 gaaaactgta tttcaaccgc tggtacagca gctctttttc tgtatgctgc cccacgaccg
    12301 ccagcccggg tttgcgctgg aaaatatagt agctgatcca gaacagcccc gccaggcaac
    12361 cggcgagatt aaacaaatag atatacagcg gcagcataaa atgactgctc atatgcatca
    12421 tcgatgccgt ggaaaaagga aaagtaacaa taaaaaacag gaaaaaaagg ttgcggtgga
    12481 tcaacccatc gtcataatgc tgtaaaaagc gacacaaatg cagatgccat ttccagaagg
    12541 tcccgataaa cataaaactc atcgcaaagg tgaaaaactc catcaggaac ggatgcaaca
    12601 cctgccggta accgcctgca ggcaagtgtt ccggcatatg cggcaacttg atttcgatga
    12661 tcaacagggt aatggcaatg gcaaacacag catcgctgaa caacacggcc ctgtccagct
    12721 caaattcacg gtgaggggtt ttagcttcct tgataactga catagacata taaaaacgta
    12781 tggcttttcg gcaatatacg aaaagctaaa gaaagccgct atccaccgtt tttttaaatc
    12841 cggtagtttc gtatattcgg ggaacagcat ctcttgtgcg accgcctccg gtcagaatta
    12901 tctatgcgtt gcggctttgt catccgccgg tagctgtttt acaacctttt ctcttttcat
    12961 ttgttaggta tttatcaatc atcatatact ttcaatgtta taagtatgcg ttgtaccctt
    13021 atattgattt ctacactttt tttgtcagga ttaaatacca cttacgggca gatggataca
    13081 accaggggaa actacgcctt taacctggcc gattgtatac aatacgggat cgcgcatcat
    13141 cacgatatgg tcaatgccaa cctggatgtg gacttttcaa gggaacaggt aaaggaagcc
    13201 accgccaagc tgttgcccca cgcggatatc aatgccaact tcaccgacaa tatgaaactg
    13261 gccacctccc tgatccccga catcgccagc ggtaactacg accgtaaaat accggtgcaa
    13321 tttggtaccc gctttgcttc caacgcgacc gggcagatca atcagaccat cttccagagc
    13381 gattatttcc tcggactgaa agcttcccgc gtataccgcg gactggccac caaaaacctc
    13441 acccgcacgg agatagatac caaagtggcc atcatcaaag cctactacgc ggtgctcacc
    13501 aaccaggaaa acatccgcct gtccaaatcc aatctcgatc agctgcgcaa aaccctctcc
    13561 gacaccaaag cccgctacga tgccggcgtg tctgaaaggg tagacgtaga ccggatacag
    13621 gtgtcctata ataatggcgt gacccggatc gaaaaccaga tccgcgaact cgtatatacg
    13681 atgcagttac tcaagttcca gatgggcatg ccgcaggaaa gtgacctcga gctccgcgaa
    13741 accgtgcagg acctcaatgt ggaagcgttt tccaccgata cgctcaacta taaagtggaa
    13801 gaccgcgtgg aatacagcat ccagaacacc cagatagccc ttaatgaact gaacctgaaa
    13861 agcaagaaga tggcctatct gccccagctg aactttttcg tcaactatgg ggtcaactgg
    13921 ttttccacca aattcggcga cctgtacaaa caaggcttcg gcgcctccgc actgggcctc
    13981 aacttgtcat ggtctatttt taccggtacc gaaaggctcc accagatcag gcagctgggc
    14041 atcaccctga aaaaatcaca aaatgatctc gacttcctgt cacagcagat aaaactggag
    14101 gtgaagagcg ctaatacatc ctacgaaagc aacagggcca cgttcgttac acagaagacg
    14161 aatatgacac taacgcaggg catatacgac aggatcgtac tgaagttcga gcagggcgtg
    14221 gctaccagcc tggacgttat ctcagcggaa agccagctta cccaggcccg cacagactac
    14281 gtcaacgcca tgctggccac cctgatcagt aaaaccgatc tggacaaagc catgggcaga
    14341 atcaaatagt atcaaagcaa atacaacaat tattaatttt ttctccatat gtacctgaaa
    14401 tcaaattgga tcataattct ggttgcgctg ctgggcaccg cctgcggtgg tggaaaaaaa
    14461 caacagcaac aggcagccat gatgggcatg atgaaggcaa ctgtcgtagc acaggaagtg
    14521 gtgccggctt cctataccgt gcacacccag ttcccggcta cgctgacagc acacgatgaa
    14581 gtggccattc gctccgatgt gaccggctat ctctccgcca ttaaagtgaa agacggcagt
    14641 atggtgaaaa aagggcagcc gctgtatgag atcgacaaaa gccggtatgt ggccgcctat
    14701 ggccaggtag ccgctaccca gcaacaggcg gaagcggacc tcgcccaaaa agaaaaagat
    14761 tacgagcgat ataaaaccct gctggagcat gacgccatct ccaaacagac ggtcgaccag
    14821 gcatataccg ccgtgatgac gtccaaagcc aacctggccg ctgccaaggc ggccgtggcc
    14881 cgcgccggca cagatgtcaa tcacgcgatc atacgcgctc cggtcagcgg cagcatcggc
    14941 atcgtacaga tcaaagtcgg tgatatcgtc aacgccggcc agacgctgat caatacgctg
    15001 gtcaacgaac atcctatctt cgccgacttc gacgtgcctc aggccagcat cccccagttc
    15061 tatcgcatcc agaaaggaca gggcgatgaa aaattcttcc tgaaattcac cagcggtgaa
    15121 acctatagcg aacaggggaa aatacaggcc atcaataata ttgtagaccc acagaccggt
    15181 accatccggg tgcggctggt gttcgggaac aaagacggtc agcttaaatc aggcatgagt
    15241 ggcgtagtgg tcatgcagta cgccacaccg gccacacagg tggccatccc ggcgaaagcg
    15301 atcgtacaga acctctccga aacgtccgtg atgaccctca cgaaagacaa tgtggtgaaa
    15361 cccgtgcaca tcacgcccgg tcccgttacc gacaccatgc tgatcgtaga agacggcctt
    15421 aaagccggcg accgcatcat cgtggaaggc ctgcagaaag tgaggccggg agataccgtg
    15481 aacgtggccg gtcccggtac gcccgcagca ccgccggcag gtaaacatta attcctaaaa
    15541 tcaccatcac agtatgattt caaaaacttt tatagagcgc aagaatacta cgatagttat
    15601 atccatcatc ctggtgattg tagggttgat ctgtatgttt aacctgccta ttgcccagct
    15661 gccagatatt gcaccccccg taacggatgt aagggccaac tatgtgggcg ccaactccac
    15721 caccgtggaa gaaacggtga cgacacccat cgaaaaccag gtgaacggta cgcccggcgc
    15781 catgtacata cagtcggtaa gcgccaacga tggttccatg agtatcaccg ttaccttcaa
    15841 cctcggcacc gatcccgata tcgccacgct cgacgtgcag aacagggtga gcctcgccct
    15901 ccccagtacg ccggacgaag taaggcgtgt aggggtgact gttaaaaaac gttccaatga
    15961 tatgttgatg gttatcgggc tcaactcgcc gaaagggcaa catacccgcg aattcctcga
    16021 caactacatc aatatttacc tcaaaccgga actggcccgt atcgaagggg tgggagacgt
    16081 gaacgccttc tcccaggact acagtatgcg tatatggctc aaccctgata agatggcggc
    16141 gctcaacctg acggcggctg acatcgcacg ggcggtgacc gaacagaacc agcaggtgcc
    16201 ggcaggcagt atcggggcgc cccccatgtc ccgcacccag gcttttgaat atacggtgag
    16261 tgtaagaggc cgcctggcca cttccgaaga attcggtaat gtggtggtcg ctaaaaatcc
    16321 gaacggtggt ctcattcgcc tccgcgatgt ggcccgtatc aaccttggct ccttcaccta
    16381 cgctatcgat gccaaagcag atggtaaaac cggtagcggt ctggctatct acctggcgcc
    16441 cggcgccaat gccctcgatg tgaacgaccg cgtgatcgcc aagatggaag aactggccaa
    16501 atctttcccg gaagatgtga actggctgat tccttttgaa acgacctcct tcgtaaaaat
    16561 atctatcaac gaggtgttcc acactttcct cgaagcgctt gcgctggtgg tgatcgtagt
    16621 gtttatcttc ctgcagaact ggcgggcgac catcatcccg atactggtga tccccatctc
    16681 gctgatcggt acttttatat tcttccagct gctgggattc tctatcaata ccctcaccct
    16741 cttcggtttc gtactggcca tcggtattgt ggtggacgat gccatcgtgg tggtggaagc
    16801 ggtccagcat catatcgacg ccgacctgat gtcgccgcgg gaagccactt tcaaagccat
    16861 gtcggaagta caggcgccgg tgatcgccat cgcgctgatc ctcgcagcag tgtttgtacc
    16921 ggtagcgttt attcccggcg taagcggacg attgtaccag cagtttgcgc tcaccatcgc
    16981 attctcggta ttgctatccg ccttcctggc gctgacgctc acaccggcgc tgacagccat
    17041 cctgctgcgg cctgcgcatc ttaccaaaaa atcacacggg ctgaataagt tcttctataa
    17101 attcaatgaa tggtttaccc gtgttaccaa ccgctacggc aacatggtga tgcgttccat
    17161 tcgctttacg ccggtggtgc ttatcctgct gggggtgctg tttgccgttg ctttttatct
    17221 ttttaagaag acacccacca cctttgtgcc ccaggaagac atgggtgccc tctttatagc
    17281 actggaacta ccggaagcag cgtctaccga acgaacaaaa caagtagtgg atgaaatcgg
    17341 tcatatcctc agcgccgaca gcgccgtaaa ccacttcttc ggcatcaccg ggatgaactt
    17401 cgtggccaac gcggtgaagc ccaactcggg cactttcttc gtgagcctca aaccatggga
    17461 cgagcgctat gcgcatggag acgatatcgg taaagtgctg ggccgtatcc agggcgcagc
    17521 gtcgcgtatc gtcggcgcca ccatcattgc catcccggcg ccgaccctgc gtggcatggg
    17581 tacgtcgggc ggcttctcgt ttatcctcga acaaaaaagt aatccggata tcaaacaatt
    17641 tatgcaggtg atggggcagt tcctgatgga agccaaccag cggcctgaaa tagcccgcgc
    17701 ttacgccttc ttcagcgcca atacgccgca gttcaacgta gaagtggaca gggacaaatg
    17761 taaacagctg ggcgtggccg tcagcgatgt gttcaacgcc ttgcagactt tcctcggcgg
    17821 cctgtacgtc aatgacttca cgcgtttcag ccgcagcttc cgcgtggtga tgcaggcaga
    17881 ctcactgtac cgtaccagca tcgacaatct cgctacttat tatgtacgca ataacctggg
    17941 gcaaatggtg ccgctcagcg cgctcatcac caccaaaaaa ggcgcaggcg ccccggtcat
    18001 caaccacttt aacctgtacc gctctgtgga gatagatggc gacagccagg tgggctacag
    18061 tagcggcgac gccatcaagg cattacagga agtggccgcc aaagtgctgc cggagaattt
    18121 cggttacgag tgggccaacg tgtccctgca ggaaataaaa gcgggcaaca gcagcgtgct
    18181 gatcttcatg ttgtctatcc tgtttgtatt cctgctgctt accgcgctgt acgaaagctg
    18241 gtccgtacca ttctccgtac tgctggcggt gcctgtggcg ttgtttggtt ccatcgtggc
    18301 gctggcgctc actaaacagg ctaacagcgt gtattcccag atcggtctca tcaccctgat
    18361 cggactggcc gctaaaaacg ccatcctgat cgtggagttc tgtaaagagc gcgtggacag
    18421 gggtatgcca ttgatggaag ctacgctgga agcggtgaag ctgcgtttca ggcctatcct
    18481 gatgacgtct tttgccttca tcctcggcgt ggtgccgttg tgcctggcgc agggcgccgg
    18541 tgcggcctcc cgcgttaata taggctacac cgttattggc ggtatgctgg cagccaccgt
    18601 gctgggggta ttcaccgttc cggtattata tgtgctcatc accaaactgg cctacggtaa
    18661 aaagaaactg gccgaactgg aagcgcacgg caacgaagag aaaaaaccga aagggctggg
    18721 tgaatagttt tattttgagt catgaaaaat acggaacgat tcagcaacag ggtaacggac
    18781 tacgagaagt accggccaca ttatccggtg gccattattc cgtacctgtc tgccaccaca
    18841 ggactttcgc acagcagtgt tattgcggat atcggttccg gtaccggcct ttcggcccag
    18901 ccgttcctcg ataatggtaa cacggtgtac gccgtggagc ccaacgaggc gatgcgggct
    18961 tcggcagagc agcaccttgg ccgtttcccc ggctttaaaa gtgttgccgc cacggcagaa
    19021 catacttccc tgcccaatca ctcggtagat ctcatcgtgg ccggacaggc tttccactgg
    19081 ttcgaccagg agctcacccg taaagagttt caccgcatcg ccaaacccga cgcctatgcc
    19141 gccctgatgt ggaacctgcg gtctgtgagt acgccgtttg aacaggatta tgaacagctg
    19201 ttgcaagagc atggtgtgga ctataaacat atgcagcaac gccatgtagg cccgatgcag
    19261 ctcgccgcat tttttctgcc tggcaccttt aaggagaaaa cttttcagaa cgcccagcgt
    19321 ttcgatttca aagcattgaa aggcttgctg tcatcttctt cgtatatgcc ggcccgttcg
    19381 catgaaaact atccggccat gatcaaggac cttgaagaca tcttccataa ataccaggag
    19441 caggggatgg taacgtttaa atacgaaacg aaactgtaca caggcagatt gagcgaataa
    19501 aaacattttt caaaaagatc atcataaaaa atcccggagc aattcgctcc gggatttttt
    19561 atgcgtcatt attctgtcat tggattcagg ccagcgcatc aaacaatatt tccaccggat
    19621 gctgtgcttt tacgccggtg ccgtctttta cctggtggcg gcagctggtg ccgggggcgg
    19681 cgatcagcgt gccggtagcg gcgttgcgta ctgccgggaa cagcaccatt tccccgatct
    19741 gcatactgag gtcgtagtgt tctttttcgt agccgaaaga gccggccatg ccgcagcaac
    19801 cggaggggat cacgtctacg gtgtagtgct gcgggataga tagcatcttt ttactgtgca
    19861 gcgcggaaga cagtgctttc tgctggcagt gcccgtgcag cttgatctgc tgtggctgag
    19921 cggtgaactg tgcagcggtg atatgccctt tctctgcctc gctggcaata aactcatcga
    19981 tcaggaaaca gtttttggcc agtgtctgcg cctgcggacg aaggttttcc cgtaccaggt
    20041 cggggtattc gtcgcggaag ctgaggatgg cagagggttc tacgcccaac aggggcgtgt
    20101 tgtcgttgat aacgttactg aatatacgta cgttttcttc tgccagttca cgcgcctggc
    20161 gcagtagtcc tttggacatg taagcgcgtg cactttccgg atggtcgatc attttcactt
    20221 cgtaaccgag gcggtgcagc agctgtactg ctttgatgcc taccggggtg tcgttgtagt
    20281 tggtgaactc gtcgcagaag agatataccg tgcggttgcc ggcgccctgt ttttctttgg
    20341 gccaggtctg gttgaaccat ttccgcagcg tggtgctatg gaggccgggc agggagcgtt
    20401 tggccgcgaa gccgctgaat ttacggataa taccgccggt aaagctgtta ttgataagtc
    20461 cattgtagat gcccggagca atggccgcga ggccggacag cttagaaaaa ttgccgatca
    20521 tccgggcgcg catgggtacg ccgttggcgt catagtagtg ttgcaggaac tccatcttca
    20581 gcttggccat gtctacattg gacggacatt ctgacttaca gcccttgcag gcgaggcaga
    20641 ggtcgagtac ttcatagatc tctttatgat cgaagcggtt ttctttggtg gagtgggtaa
    20701 ggaactcacg caggatgttg gccctggcgc gggtggtatc tttttcgttg cgggtggcca
    20761 tgtagctggg acacatggta ccgccgctca acggtgtttt acggcagtca ccggagccgt
    20821 tgcactgctc ggcgtgttgc agcacggttt gttccgggaa gtggaagatg gtatggaagt
    20881 ccggtgtttt ttgtccgggt tcgtaacgca gcatactgtt catggacggc gtgtccacga
    20941 ttttattggg attgaagata ttttcagggt cccac
//
