LOCUS       NZ_FUWZ01000001        24393 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000001
VERSION     NZ_FUWZ01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1884029
            Orig. end                         :: 1908422
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24393
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="6"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24393
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24393
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14393](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14393
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            264..1583
                     /locus_tag="B5D63_RS07865"
                     /old_locus_tag="SAMN04488128_1011566"
     CDS             264..1583
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014223391.1"
                     /locus_tag="B5D63_RS07865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011566"
                     /product="gluconate:H+ symporter"
                     /protein_id="WP_078668162.1"
                     /transl_table=11
                     /translation="MAFLIVIVCILLLMVLVTLAKCNVFVAFLIVSALAGWWLGMPLQS
                     ITGAMQKGIGDTMGGLLIIIILGAMLGKLVAESGAARQIAQTLIRLFGTRYIQWALLVA
                     GFVIGIPLYYGVGFVLLVPLIFSVVYQYKLPAVYIGLPTLAALSVTHGFLPPHPSPVAL
                     VTQFHANMGLTLVYGLIVAVPAIIVAGPLFARYLKKIPASPSPLFQAQENQAQQLPGAF
                     NSFFTALLPVLLLVITTGLLHAAPANSQLYGFLSFAGDASVVMLCCLLIATFSLGIAQR
                     KSLKDIMNIYAESVKDIAMVMLIIAGSGALKEVLANSGVSARIAMAMSSWHIPVLVLGW
                     LMAAVIRASIGSATVAGLTAAGMMAPFIATGQVDPNLMVLSVGAGSLMFSHVNDAGFWM
                     FKEYFNISIKDTFLSWSVMETIVGIMGLLGVLALNALITH"
     gene            1605..2069
                     /locus_tag="B5D63_RS07870"
                     /old_locus_tag="SAMN04488128_1011567"
     CDS             1605..2069
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008587267.1"
                     /locus_tag="B5D63_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011567"
                     /product="RidA family protein"
                     /protein_id="WP_078668163.1"
                     /transl_table=11
                     /translation="MESKAAEKLKALGLELPPAPTPLGVYKPFLIDGKYLYLSGHGPVQ
                     QDKSLIIGRIGSELDMEQGKLAARQVGLTMLSTIQTHVGLEKVKRVIKVLGMVNCTPEF
                     ERHPYIINGCSELFAAIWGEENGIGVRSAVGFGSLPDNIPVEIEALFELY"
     gene            2124..3161
                     /locus_tag="B5D63_RS07875"
                     /old_locus_tag="SAMN04488128_1011568"
     CDS             2124..3161
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014223393.1"
                     /locus_tag="B5D63_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011568"
                     /product="sugar kinase"
                     /protein_id="WP_078668164.1"
                     /transl_table=11
                     /translation="MQKQEETTAVRLAAFGEFLLRLHSNSGKRFGQSDGYIPYYAGAEA
                     NVCVLLSRLGISTEYITRVPDNDLAVTGLQHLRGHGVGTGRVVYGGDRLGLYFTESGNG
                     IRPGRVIYDRTGSSFATLQPGEIDWASALAGINVFHWSGVAAALSASSAAVCAEALAAA
                     QAAGLTISSDFNYRATLWKYGQHPSAVMPALLQHSDMTVADLDAVNVYYNIETDKQLPP
                     EKRFEQCYDQLRRHMPKLKTLAMSFRKVQGNQLMYFGALAQDDRYYFAEGFTVPQVTDQ
                     IGAGDAFTAGILFGVMNQHPPQRTIDFAVACGTLKQSIHGDWALVNEREVTDLMANGPS
                     GRIVR"
     gene            3173..4243
                     /locus_tag="B5D63_RS07880"
                     /old_locus_tag="SAMN04488128_1011569"
     CDS             3173..4243
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018611922.1"
                     /locus_tag="B5D63_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011569"
                     /product="dipeptidase"
                     /protein_id="WP_078668165.1"
                     /transl_table=11
                     /translation="MFTIDAHLDLSMNALEWNRDLRQPVTAIRKREAGLQDKPDREKGV
                     VAFPELRKGNVGLVVATQIGRYVAPDNPLPGWHSPEQAWAQTQGQLAWYKAMEDAGEMI
                     MIKDLPALEQHVALWNDGTPNDRKPIGYILSLEGADSLVTIDHLHRAYQNGLRAVGPAH
                     YGPGRYANGTDATGHLNEQGRQLIREMEQLNMILDATHLCDDAFWDAMDIFNGAVWASH
                     NNCRALVNHNRQFSDEMIKILIQKGAVIGGALDAWMMVPGWVRTQSTPEGMQCNLEKLI
                     DHMDHICQIAGNALHVGIGTDLDGAFGKEQCPYDLETIADLQKLPDMLSRRGYKAADIE
                     NIMHGNWLRFLRKAWK"
     gene            complement(4355..6436)
                     /locus_tag="B5D63_RS07885"
                     /old_locus_tag="SAMN04488128_1011570"
     CDS             complement(4355..6436)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.5"
                     /locus_tag="B5D63_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011570"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_394333846.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.4e-26, bitscore:
                     90.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADISHRSTQEIYTGEEPLNIVADDKGTQCVFLTRSNDKATTFWY
                     YHRDQTGKAIVAAPHMQLQNEMTFGSFEKFSGDGSFIHCVLTGDYPAPPAPNPARLRLR
                     TFMDTKLNKEEDPLRCQAIWYLHNNTIRQVQDKEESPFYLAGFYAGSYNPRSTLKLLDK
                     TLAHKGEWNWNENALSSRSLVDLTNGSKKLVTLPGDRNSASYALSPQGKWIIYYDAGQQ
                     NYFSYNVATSERKNITAGITATWTTYDNDDIPFAPYLNLPLGGFSDDETKLYLYDQHDI
                     FQIDLTGKSAPVNITEGYGKSHNIVFRFAFPPNERTGKNILLTAFNRSTKEDGFFDIVK
                     GKLRQLSMHPFIFTGPEESKYHLRTPPVKAKNADVYLVQKMEAASAPNIYVTKDFIHFD
                     AISDIHPERRVNWLTTELIDFNTRDGKPAQGILYKPENFDPNKKYPVIFYYYEKISECL
                     HLYIRPEPSMGPMNIPYFVSNGFLVFTPDVHFDIGYPGRSSLQTVLGAADKLVQLPYVD
                     STRMGLQGHSFGGFQTNYIITHTDRFAAACSAAGFTNFVSAYGSIIGSGYSRQGQYELY
                     RDRIGASLWERPDLYQENSPVLNIDRIKTPLLLMHNMEDNDVPVGQGIEFFTGMRRMGK
                     VVYFLQYEGQGHSIFDKPALDYNRRMFEFFSYYLKGAALPAWMTDKRAKILHAKGLKN"
     misc_feature    complement(6461..6477)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.46"
                     /tool="antismash"
     misc_feature    6624..6633
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    7025..7039
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.67"
                     /tool="antismash"
     gene            complement(7057..7296)
                     /locus_tag="B5D63_RS07890"
                     /old_locus_tag="SAMN04488128_1011571"
     CDS             complement(7057..7296)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_1011571"
                     /product="hypothetical protein"
                     /protein_id="WP_078668167.1"
                     /transl_table=11
                     /translation="MKKSALLLSAVFIISVIAGVVASKARVNHRIYVPYDNEDVCDHTL
                     TGKEIPGPDHNGANATTVPGQPCSKVFITDNPQN"
     gene            complement(7583..8365)
                     /locus_tag="B5D63_RS07895"
                     /old_locus_tag="SAMN04488128_1011572"
     CDS             complement(7583..8365)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010171.1"
                     /locus_tag="B5D63_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011572"
                     /product="fatty acid desaturase"
                     /protein_id="WP_078668578.1"
                     /transl_table=11
                     /translation="MNHTDIQRKVDWKDLRHLTVPEMLIENNLTIPWLLVSWVLAWKGY
                     YLAALPFSAFFFLTALRQVHNGFHQSLGTHKRLTWLSLFLNSVLMMASMNAVKYNHIRH
                     HKYCLSEEDYEGKSASMSWYGAILYGPVHMFHIHRVTLQTANKKYVRNTLLELSAITVF
                     ATTVFLLDLHFLIYHIIVMLTGECLMAFFAVWTVHHDTTETPELARTQRGTWKNKLTFS
                     MFYHLEHHLFPAVPTIKLPELAKRIDAVLPDLEKKQTF"
     misc_feature    complement(8459..8472)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.48"
                     /tool="antismash"
     gene            8657..8833
                     /locus_tag="B5D63_RS34960"
                     /old_locus_tag="SAMN04488128_1011573"
     CDS             8657..8833
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038153.1"
                     /locus_tag="B5D63_RS34960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011573"
                     /product="class I lanthipeptide"
                     /protein_id="WP_159455932.1"
                     /transl_table=11
                     /translation="MKKKKIDLAKKLTLAKETVATLTVKQKEAVKGGETVFCDTYDPAW
                     TCESNPRPTNVCM"
     gene            8894..9091
                     /locus_tag="B5D63_RS07900"
                     /old_locus_tag="SAMN04488128_1011574"
     CDS             8894..9091
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038153.1"
                     /locus_tag="B5D63_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011574"
                     /product="class I lanthipeptide"
                     /protein_id="WP_078668168.1"
                     /transl_table=11
                     /translation="MRKKKISLGKKLSLNKATVATMTIRQQAVIGGGPFTVMPRCIETV
                     AQTCITYMPGQDQCYICPEG"
     gene            9151..9339
                     /locus_tag="B5D63_RS34595"
     CDS             9151..9339
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038153.1"
                     /locus_tag="B5D63_RS34595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I lanthipeptide"
                     /protein_id="WP_143312805.1"
                     /transl_table=11
                     /translation="MKKKQIVLSKKLLLRKDTVASLNVQQQAKIAGGVPLTWWSACCQN
                     TREVTCPEGCVRTSEPK"
     gene            9419..9601
                     /locus_tag="B5D63_RS34600"
                     /old_locus_tag="SAMN04488128_1011575"
     CDS             9419..9601
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038153.1"
                     /locus_tag="B5D63_RS34600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011575"
                     /product="class I lanthipeptide"
                     /protein_id="WP_143312806.1"
                     /transl_table=11
                     /translation="MKKKTLQLSKKLLLKKDTLVTLNQQDQAKLAGGAPLTWWSACCVE
                     TDEVTCPAGCVRTTK"
     gene            9670..9870
                     /locus_tag="B5D63_RS07910"
     CDS             9670..9870
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038153.1"
                     /locus_tag="B5D63_RS07910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I lanthipeptide"
                     /protein_id="WP_143312807.1"
                     /transl_table=11
                     /translation="MKKKKIDLSKKLALNKETVASLNISQQQQLVGGVATRDIVCMEDT
                     RYISSCRATRPSPNSPCCQIP"
     CDS_motif       9670..9756
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKKKIDLSKKLALNKETVASLNISQQQQ"
                     /locus_tag="B5D63_RS07910_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9757..9870
                     /prepeptide="core"
                     /locus_tag="B5D63_RS07910_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-11.60"
                     /molecular_weight="3871.4"
                     /monoisotopic_mass="3868.9"
                     /core_sequence="LVGGVATRDIVCMEDTRYISSCRATRPSPNSPCCQIP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKKKIDLSKKLALNKETVASLNISQQQQ"
                     /leader_location="[9669:9756](+)"
                     /alternative_weights="3889.5"
                     /alternative_weights="3907.5"
                     /alternative_weights="3925.5"
     gene            10001..11206
                     /locus_tag="B5D63_RS07915"
                     /old_locus_tag="SAMN04488128_1011576"
     CDS             10001..11206
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="B5D63_RS07915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011576"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_078668171.1"
                     /sec_met_domain="LANC_like (E-value: 1.1e-39, bitscore:
                     133.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNTATQLRYIYHDIIPLLKERKYKADYNTSLFKGPWGALLFMFY
                     YEQYADDQADNATALLEELYAEYAPEKGDNYAFCNGHTGPFWLLEHLTRHEFLDLDINE
                     LASDFVTATILQSNFHLEHQNYDFLHGSSGMCNFLLRFASRPDVAEHLGHFVQKLWDNS
                     VMTDKGRSLPFFYTHDKPEGIFCNSFSLAHGSCSLLIIVAKIYEAGIAKERCQSLITES
                     IPFILQNQNAVSDDSMHALYPAILDGKSTDSRLSWCYGDLNVAMMLWHCGKVFGEEHWK
                     EEALHIMRYNMRRDTDEAAGIVDNCLCHGSGGIAAFYRKFWFETGDEAFLRCANHWQEK
                     ATEKIVFPEDHSKHGIKMWLGKDKQWEYVWDLLDGSSGVGLSMLSQMHPQALPWDECFL
                     LS"
     gene            11241..14393
                     /locus_tag="B5D63_RS07920"
                     /old_locus_tag="SAMN04488128_1011577"
     CDS             11241..14393
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="B5D63_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011577"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_078668172.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.5e-173,
                     bitscore: 574.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.3e-07,
                     bitscore: 29.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5e-60, bitscore:
                     200.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALSHTGFFLLRSPLYPVNRYRDVLEDSLQELADKNPLFLYALCI
                     ASGDLLKELERFLSDPASFNKKKTDKLRKSLYKYWVRACSRSTPYGLFAGCTTGAIGAD
                     TQLRINDVKDAYQYVRLDMDYYTRICYHISQQADISTALRYYPNNSIYKTGDKYRYAEY
                     TINNNRRKYLLTAVEDSVFMSAIIREAAAGLTITQIVQVIHEQDPSITEEEATSFVREL
                     IDSQLLIADTEPRITGEDNLQSLTDRLLSIPDANTFRDALLALQALFRQQDFERSRLAA
                     IHQQCENAFPISIPKDLLQIDLFKTAQQCQLSETLVNDILSQIHRLMALCHGYTKGQTE
                     LSSFITRFMERYESQEVPLNLVLDGETGIGYGAAIENTVHAPFVEDVAGAPGAENQTVS
                     WSPLQQLSLDKYEQFLQQGLSEVTITDDDLQKLGDPETVPMARSCYLFGSLQAASAEAA
                     DKGEYQFALNSMGGPSAANLLGRFCNGDEVLTEKVKSILDEEAAAFPDLLLAEVVHFPE
                     ARAANVLIRPTLRPYEIPYIGVAGTPEEYRIPVNDLLVSVRQNEVILRSKRLNKRVIPR
                     LSSAHNYGYNSLPIYKFLCDLQHQSVMSYLSWDWGVFGNRKRLPRVVYKNIILSKATWT
                     LTAKETAHLGDDAEANQRFMDQYREQQKMPEKVLLAESDNELLLDLTAPAAVGLLLDHV
                     KKMSSVKLKECLLAEESGIVRDTDDQAYAHELLLPLRSVPVAEKTAAEKPAAEKPRPAA
                     IAAPATMPVRSFAPGSEWLYVKVYCGFRVAEELLATWFAEQLPQWQEEGLFDEFFFLRY
                     GDPLPHIRLRFRNHQRSNNDVVLHRIQTGLQPLVDNGQVSKIQCDTYIRELERYGSATM
                     HLSEQLFSADSMAVLGVVSMLEGAEGEDYRWRMALRGTDMLLEDFGLTPTERKQLLAGL
                     REGFTTEFGGAKTQHKPLNDKYRKHQQEIASFLRAENDEANDIAEAVEFFRQRSEITAP
                     VAQQIRQHYQNDNRYFDILASHIHMFLNRIFVAKQRKHEMVIYHFLEKYYLSQLAMEAT
                     LK"
     misc_feature    complement(11263..11277)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.24"
                     /tool="antismash"
     aSDomain        11679..11942
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B5D63_RS07920_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.90E-09"
                     /identifier="RREFam001.1"
                     /label="B5D63_RS07920"
                     /locus_tag="B5D63_RS07920"
                     /protein_end="234"
                     /protein_start="146"
                     /score="29.1"
                     /tool="antismash"
                     /translation="PNNSIYKTGDKYRYAEYTINNNRRKYLLTAVEDSVFMSAIIREAA
                     AGLTITQIVQVIHEQDPSITEEEATSFVRELIDSQLLIADTEP"
     gene            14394..16592
                     /locus_tag="B5D63_RS07925"
                     /old_locus_tag="SAMN04488128_1011578"
     CDS             14394..16592
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012788945.1"
                     /locus_tag="B5D63_RS07925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011578"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_078668173.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2e-35, bitscore:
                     118.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFTTYRQLDAMDCGPTCLRMVAKHYGREYPLDYLRELANITREG
                     VSLLGISEAAEKIGFRTNAVKITFEQLDENVELPCILHWNQQHFVVLPPQNYNRHNPKD
                     KILVADPGHGLVKVDKETFLHCWQGKQNHGVVLMLEPGEQFLRQEGPQRAATGFRFLFS
                     YLRPYRKYVVQLFLGLILASLLSLIMPFLTQSLVDYGINRHNVHFVYLILISQLVLFAG
                     STAIEMIRSWILLHMNSRININIISDFLIKLMKLPIRFFDSKMIGDIHQRIGDHTRIQN
                     FLTGTTLSTLFSFVNLLVFTAVLAVYSMKILLVFVLFSTAAVGWIFFFLRRRKALDYRR
                     FQRMSDNENVLFELITGMQEIKLNNCETARRWEWEHVQAGLYRINVKSLALGQYQQIGS
                     VFFNQLKNILISFISAREVMNGNLTLGMMLSVSYIIGQMNSPLDQLLTFIQSAQDAKMS
                     LDRLGEIHNRQEEEKRELIAPPSSRSDGSGDIVLENLSFQYGGAKSPFVLKDIDLVVPE
                     GKVTAIVGTSGSGKTTLMKLLLQFYEPTSGQIRIGEQDLQQLSPKWWRRQCGNVMQDGF
                     IFSGSIAKNIAISDETINNDKLVHAAEMANIRDFIEDLPLGYQTKIGNAGSGISAGQKQ
                     RIQIARAIYKNPHYLFFDEATSALDANNERVIMDNLEQFFRGKTVVVIAHRLSTVKHAD
                     QIIVLDRGRIVETGNHATLTARKGNYFELVKNQLELGG"
     misc_feature    complement(14408..14428)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            16597..17145
                     /locus_tag="B5D63_RS07930"
                     /old_locus_tag="SAMN04488128_1011579"
     CDS             16597..17145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS07930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_1011579"
                     /product="hypothetical protein"
                     /protein_id="WP_078668174.1"
                     /transl_table=11
                     /translation="MPEKKTIQHLNGHTLHPSLTEVRSEEVQEIMGKMPPWMVRSGITM
                     IGIAMVLALVGAWFFRYPDVLPMPVRVTPQERSFIVQGHIPAADAWRVKAGQQVMLSLT
                     AYPSDTYGLLPGTVTTDAVAETDSSFRVEVKLTQGMLSTSGKQIPVQPVLTGTAEIMTD
                     DKSLLQRILGKALAPLMTD"
     gene            17292..18452
                     /locus_tag="B5D63_RS07935"
                     /old_locus_tag="SAMN04488128_1011580"
     CDS             17292..18452
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF026253.5"
                     /locus_tag="B5D63_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011580"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_078668175.1"
                     /transl_table=11
                     /translation="MKNKIVLLVGCLITKIVIARQAIVAFIPDESIRAIGLFTEGLAWA
                     STGDGNYGYLDTTGKMVIAPKFREAGIFSEGLALVGQSVNGNMRYGYVNRQGRLVIPCQ
                     YDDAHNFSCGRAAVRTKGVWSYIDRQGKTAFVRMDTPIENAPPLSFHNGRLLVRKGKLY
                     GFVDTSGRWAVPPTFAWAKEFADGVAVVAGKEIKSDSMPGNGQLAQLYNRLPAGKPEYM
                     TNVIDSTGKLLFTTDVKGLKEFTNGVSFFLRDDQWGLMDKTGKILMVPTFDDLPYAISS
                     GVFFKQVNGTAEGNKDGYLQIYNTAGRPTGKMPLCDAAGNCMYDSHGAYHSNLLAVQIG
                     DNWGFADTSGKIVIAPVYKTVSDFAGTHAVVKTADGKLQVLRNPAL"
     gene            18475..20796
                     /locus_tag="B5D63_RS07940"
                     /old_locus_tag="SAMN04488128_1011581"
     CDS             18475..20796
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF026253.5"
                     /locus_tag="B5D63_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011581"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_078668176.1"
                     /transl_table=11
                     /translation="MKKRTFVIRLAGSLLLLAGTALAQTPETAGYLDRFEGEFAKIQLN
                     GRQQLLHRSGKVVVDKIQELSYYRLVSAVKQDAYGVVNRKGDIIAPFRYDAVRILGESK
                     QDNPAENYCLITVKLQGKTGAIDSLGKVLCEPEYSDIGVLTPKTFSIKKNGLYGWCDMK
                     TGKVLQEPKYTEVSRSYVVDGLINIQLQGKSGLSQEDGTILVPPKYERFMGWNSRQLFS
                     YYVPGGKCGLMDRQGKVLTPAIYDDINAGPSDALVAVKVQDKTGLLDVATGQLKTPMLY
                     TRADRLGPLFTVWKGNLCGLTDALGKEIIPVAHTDLQLFDSKGHNVLGAVVSLGPSSAG
                     YTPPYYVVAKKGNTAAFYDAAGKQLLPFEYDDIRVTSRNDKAYVSLLKGTQCGLADISG
                     KIIVPVQFSGIDNNYGISNYDDDAAGTEKNNFIAVLKVIREGVIGIGLFNMATGQLVIP
                     AVYSGLRWQNDNMIRLEQGDSSGLADKTGRIIRPLKKYGAFDAVSPDLIVEKRYYDDGS
                     ATLLVNKEGRVLYDSKHWEFSATASNRLLVPDARKTWPLQFNSGLLKVRGYSYENQFVD
                     TTGKLMAFEEYKYVGDFYNRRAVAITQDDRVGIISIDKKVVYPLELDDLTSADNELLKM
                     KQGKKVGLLRKDGSVFLPLEYDHIDRVYDTALYIVTRQGKKGVLNAEGKELVPADYDEI
                     RYSRDDRMFEVTKDDKEGLLGADGSILVPPVYDDLEQNRTWGDHSKFPVLVKQGEWYLY
                     LDAQGKPLPYRAKKKKGYNE"
     misc_feature    complement(18484..18497)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.14"
                     /tool="antismash"
     gene            20789..23197
                     /locus_tag="B5D63_RS07945"
                     /old_locus_tag="SAMN04488128_1011582"
     CDS             20789..23197
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF026253.5"
                     /locus_tag="B5D63_RS07945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_1011582"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_159455933.1"
                     /transl_table=11
                     /translation="MNKKIIFFIALLLAGHTLPAQQGSVFTNGLARIVTKEKSWFIDTT
                     GQKVFDKIVAVYHPVDSIVEGSIYSNTEKNMLIVSSNGKKGLVNEKGQWVLKPEYDTLE
                     VRFNTYLAVYRQGKMTYADTWGKLLVPLQFEQVGILDDDRYDVKQQGKWGIYDVRRQQL
                     VIPAVYDEFDYCGGCGRKSDYLYAKKNGRWGIISAANEELVPFAFDHSHSRMRSDEWVC
                     SFRQNGKDVVVNIPRKKVYGEPLYSQMEVIGDGMLKLQKDGHFGLINRQGEQVLDFVYD
                     DISDPYGQFASGPFLTIRKEGKTGIVDMNGRMVIPPSLDEEIICSDDYIVAARNGMYNV
                     FDSAGKPLLKEDYSEIEPLKITGGAPLFALKQKALYGFFNPVNGKIVAPAFHEIDVISS
                     GKSKGMVQVTYQGKSGLYRPDGSQLLPLKYSSYELLNDHVLMVTTGAGTGLFDANTREE
                     IIPAKFKYMSRLSQDSTLLSVTSENESGDPVYGLYHISGKELAPPVYTYISALNQEHYL
                     LTKEKTHAVLSLSTGKIAALPYTDVVPAHAANLLVVSDGRQSWLWNVVENKTVSPPFPM
                     VRKYEDDTVLTSPIGTFAFGVALLEKNGKMGVINTSGKEVVPVIYDGASLLKQGVVLLA
                     RKNGDAWKYGYVDTTGKLLVPLEYDYNVNGYIYDYEDSTYLPLYKSEGGYSRAYKKGIA
                     GRDGKVLVPAIYDRVFVGIGGTGFLADKDRQFTILNAAGKEVTSAKFSAVMLDPSVNPQ
                     ADAAVLSYPLLCRQGERYVYLLSNGKTLPLQLTAVIRFEEFDNTIGYHP"
     misc_feature    23838..23854
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.99"
                     /tool="antismash"
     misc_feature    23976..23989
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.6"
                     /tool="antismash"
     misc_feature    24251..24264
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
ORIGIN
        1 ctggtgtttg aagtgtcggc cgatggtaaa atttttgagc gtgtagccgc cgctgatagt
       61 ttcccggtga atggtattaa ccaggtacgg ttgaccgtaa agcccgtacc cgcaagatat
      121 attaaagtga cggcggtcaa caagggggtg atcccggcgg gagagtatgg agcgggtggc
      181 agggcgatga tgctggcaga cgaaattatt gttaactgat gctgtgcgta ttgattccac
      241 gttagcatta cattttatac ggcatggcat ttttgattgt tattgtatgc atactgttgc
      301 tgatggtgtt ggtaacactc gccaaatgca acgtgtttgt ggcttttctg atcgtatccg
      361 cgttggcagg ctggtggctg ggtatgccct tgcagtccat taccggcgcc atgcaaaaag
      421 gcatcggtga tacgatgggc gggctgttga tcatcatcat cctgggcgcc atgctgggca
      481 agctggtggc ggagagtggc gcggcgcggc agatcgcgca aacgctgatt cgtttgttcg
      541 gtacccgtta tatccaatgg gcactgctgg tggccggatt tgtcatcggc attcccctgt
      601 attacggggt aggctttgtg ttactcgttc ctttgatatt ttctgtggtc taccaataca
      661 agctgccggc ggtatatatc gggttaccca cgctggcggc tttgtctgtc acccatggct
      721 ttttaccgcc gcatccttcg ccggtggcgc tggtgacgca gtttcatgcc aatatgggtc
      781 tgacactggt atacggactg atagtggctg ttcctgccat tatagtggcg gggccgttgt
      841 ttgcccgtta tctgaaaaag atacctgcgt cgccatcccc gctttttcag gcgcaggaaa
      901 atcaggcgca gcagttgccc ggcgcgttca acagtttctt caccgcctta ttgcccgtat
      961 tgttgctcgt tattaccacc gggttattac atgccgcccc ggcgaattcg caactatacg
     1021 gttttctctc ttttgccggc gacgcttcgg tggtgatgct atgctgcctg ctgatcgcca
     1081 ctttttcgct gggcatcgcg cagcggaagt cactgaaaga tatcatgaac atatacgcag
     1141 aatcggtcaa agacatcgct atggtgatgc tgatcattgc tggatcgggc gctttaaagg
     1201 aagtgctggc caatagcggt gtaagtgcgc ggatagccat ggcgatgagc tcctggcata
     1261 tcccggtgtt ggtgctgggc tggctgatgg ccgccgtgat ccgtgccagt attggttctg
     1321 ctaccgtggc aggccttacg gctgccggta tgatggcgcc gtttatcgct accgggcagg
     1381 tagaccccaa tcttatggta ttgtcagtag gagcgggcag cctgatgttc tcccatgtga
     1441 atgatgccgg cttctggatg tttaaggaat actttaacat cagcataaaa gataccttcc
     1501 tgtcatggtc cgtgatggaa actattgtag gcatcatggg cctgttgggg gtattggcgc
     1561 tcaacgcgct gatcactcat taagcattta ttaaaccaga atatatggaa agcaaagcag
     1621 cagaaaaatt aaaagcatta ggcctggaat taccaccggc gccaacgccc ctgggcgtgt
     1681 acaaaccttt cctgatcgac gggaagtacc tttacctgtc tggtcacggg ccggtgcagc
     1741 aggacaagtc gctgatcatc ggcaggatcg gcagcgagct cgatatggaa caaggcaagc
     1801 tggccgcacg gcaggtgggc ctgaccatgt tatccaccat tcagacgcat gtgggactgg
     1861 aaaaggtgaa gcgcgtgatc aaagtgctgg gcatggtgaa ctgtacgcct gaatttgaac
     1921 ggcatcctta tatcatcaac ggttgcagtg aactgtttgc cgccatatgg ggcgaagaga
     1981 atggtatcgg tgtacgcagc gccgtaggct tcggctccct gcccgacaat atcccggtag
     2041 agatagaagc tttgtttgaa ttgtattagg atggccgcag cagatgccgg ggaaaatatt
     2101 atctttccct taaaatttgg atcatgcaaa agcaggagga aacaacagca gtcaggctgg
     2161 cggctttcgg tgaatttctg ctgaggcttc acagcaacag cggcaaacgt ttcggtcagt
     2221 cagacggata tattccttat tacgccggcg cggaggccaa cgtatgcgta ctgttgtccc
     2281 gcctgggcat atccacggag tatatcacac gggtgccgga caacgacctg gccgtaacag
     2341 gactgcaaca cctgagaggt catggcgtag gcaccggcag ggtggtgtat ggcggcgaca
     2401 ggctgggatt gtattttaca gaatccggta acggcatacg ccccgggcgt gtgatctacg
     2461 accgtaccgg ctcctccttt gccactttgc agcccggaga gatcgactgg gcatctgcgc
     2521 tggcaggcat caacgtgttt cactggtccg gcgtggcagc agcgctatcc gccagcagcg
     2581 ccgccgtttg cgcagaagcg ctggcagcgg cacaggcggc aggccttacc atctcgtcag
     2641 attttaacta ccgcgccacg ctctggaaat acgggcagca cccttcagcg gtaatgcctg
     2701 cgttactgca gcacagcgat atgacggtag ccgacctgga cgcggtgaac gtgtattaca
     2761 atattgaaac agataaacag ctcccgccgg agaaaagatt cgaacagtgt tatgaccagt
     2821 tgcgccggca tatgccgaag ctgaaaacgc tggccatgag cttccggaaa gtacagggca
     2881 accaactcat gtatttcgga gcgctcgcac aggacgaccg gtattatttt gcagaaggat
     2941 ttactgttcc gcaggtcacc gaccagatcg gcgccggcga tgctttcaca gcaggcatcc
     3001 tgtttggcgt aatgaaccag cacccgccgc agcggaccat tgatttcgcc gtcgcatgcg
     3061 gtacgctcaa acagagcatc catggcgact gggcgctggt aaatgaacgg gaagtgaccg
     3121 acctgatggc caacggccct tcaggacgaa tagtacgata actactctta ttatgtttac
     3181 gattgatgca cacctcgacc tcagcatgaa cgccctggaa tggaacaggg acctgcggca
     3241 gccggtaacg gcgatccgca aaagagaggc ggggctacag gataaaccag acagggaaaa
     3301 aggcgttgtt gcttttcccg aactgcggaa aggtaatgtc ggcctggtag tggccacaca
     3361 gataggtcgc tatgtagcgc ccgacaaccc attgcccggc tggcactctc cggagcaggc
     3421 ctgggcacag acacagggac agctggcgtg gtacaaggcc atggaagatg caggcgaaat
     3481 gatcatgatc aaagacctgc ccgcactgga acaacacgtc gccctgtgga acgacggcac
     3541 gcccaatgac cgcaaaccta tcgggtacat cctcagcctc gaaggtgctg actcgctggt
     3601 aaccatcgat catctgcaca gggcgtatca gaacggcctt cgtgcggtag gcccggccca
     3661 ctacggcccc gggcgttatg ccaacggcac ggatgctacc ggtcatctca atgaacaggg
     3721 acgccagctg atacgggaaa tggagcaact gaacatgata ctcgacgcca cgcacctctg
     3781 cgacgacgct ttctgggacg ctatggacat cttcaacgga gcggtatggg ccagccataa
     3841 caactgccgc gccctggtga atcacaaccg ccagttcagc gacgagatga tcaaaatact
     3901 cattcagaaa ggagcagtca tcggcggcgc actcgacgcc tggatgatgg tgcccggatg
     3961 ggtgcggaca cagtccaccc ccgaaggcat gcaatgcaac ctcgaaaaac tcatcgatca
     4021 catggaccac atctgccaga tagccggcaa cgccctgcat gtaggcattg gcacagacct
     4081 ggacggcgct tttggaaaag agcaatgtcc ctatgatctg gaaaccatcg ccgacctgca
     4141 aaagctgccg gatatgctgt ccaggcgagg ctataaagct gcagatattg aaaacatcat
     4201 gcatgggaac tggctacggt tcctgcgtaa ggcatggaaa taacgcacgc gatgcctttc
     4261 acgcaaagac gctaagtttt ttatttttta ttaagagcgc aaaggagcgg agatcaaagt
     4321 tgttcttcgc tcctttgcgc tcttataaca taaattagtt cttgagaccc tttgcgtgca
     4381 aaattttcgc gcgtttgtcg gtcatccagg cgggcagcgc ggcgcccttc aggtaatagc
     4441 tgaaaaactc gaacatgcgt ctgttataat ccagtgcggg cttatcaaat atgctgtggc
     4501 cctgtccttc gtattgcagg aaataaacca ctttgcccat ccgtctcatc cccgtgaaaa
     4561 attcaattcc ctgtcccacc ggcacatcat tgtcttccat attatgcatc agcagtaaag
     4621 gggtttttat tctatcgata ttcaataccg gggagttctc ctggtaaaga tcgggccttt
     4681 cccagagaga ggcgccaata cgatcgcggt acagttcgta ctgcccttgc cgtgagtacc
     4741 ccgagccgat gatggagccg taggcactga cgaaattggt aaagcctgcc gcagaacagg
     4801 ccgccgcgaa ccggtcggta tgcgtgatga tatagttggt ctgaaaacca ccgaagctgt
     4861 gtccctggag gcccatccgg gtggaatcga catagggcag ttgcacgagc ttgtctgccg
     4921 cgcccagcac ggtttggaga gagctgcggc cgggatatcc gatgtcaaag tgaacatccg
     4981 gtgtgaaaac gaggaagccg ttgctcacga aataggggat gttcatcggt cccatactgg
     5041 gttccggccg gatataaaga tgcaggcatt cgctgatctt ttcataataa taaaagatga
     5101 cagggtattt cttgttggga tcgaagttct ccggtttata taaaataccc tgtgcaggtt
     5161 ttccatccct ggtgttgaaa tctatcagtt cggtggtcag ccagttgacc cgccgctccg
     5221 gatgtatgtc gctgattgcg tcaaagtgaa taaagtcttt tgtaacatag atattgggag
     5281 cgctggcagc ctccattttc tgtaccaggt atacatcggc atttttcgct ttcacgggtg
     5341 gcgtgcgcag gtggtatttg ctttcttccg gaccggtgaa aatgaacgga tgcatgctca
     5401 gctggcgcag ctttcctttt acgatgtcaa agaagccgtc ttctttggtg ctgcggttga
     5461 acgcggttag caggatgttt ttaccggtac gttcattggg ggggaaagcg aagcggaaca
     5521 cgatattatg ggatttacca taaccttcgg ttatgttgac gggcgcggat ttcccggtga
     5581 ggtcaatctg gaaaatatcg tgttggtcat acaggtatag ttttgtttca tcgtcactga
     5641 atccgcccag cgggaggttg agatagggtg cgaaggggat atcgtcatta tcgtaggtgg
     5701 tccaggtggc ggttatgccg gccgtgatgt tttttcgttc gctggtagct acgttgtagc
     5761 tgaaatagtt ttgttggccg gcatcgtagt agatgatcca tttgccttgt ggcgacaggg
     5821 cataggatgc gctgttacgg tcgccgggca gggtaaccag tttttttgac ccgttggtga
     5881 ggtctaccag cgagcgggaa gacagggcgt tttcattcca gttccattct cctttatggg
     5941 ccagtgtttt atccagcagc ttcagggtgc tgcgtggatt ataggagccg gcatagaagc
     6001 cggcgaggta aaagggcgat tcttctttat cctgtacctg ccggatagta ttgttatgga
     6061 gataccatat tgcctggcag cgcagcggat cttcttcttt gttgagcttt gtgtccataa
     6121 aagtgcgcag gcgtaaacgt gccgggttgg gcgctggtgg cgccggatag tcgccggtga
     6181 gcacgcagtg gataaaactc ccgtcgccgc tgaacttttc gaagctgccg aaggtcattt
     6241 cgttttgtag ctgcatatgg ggggccgcta cgatcgcttt tcctgtctgg tcgcggtgat
     6301 agtaccagaa ggtggtagct ttatcattgc tgcgtgtaag gaagacgcat tgtgttccct
     6361 tatcgtctgc aacgatattg agtggttctt ccccggtgta aatttcctgt gtgctgcgat
     6421 gggagatgtc cgccatttgg aggcgatagg tgacggagtc tgtctggctt ttgagcaaaa
     6481 gaaactggcc gttgccgctg ggcagatagt cggaaatgtc gctgaattgt tgtacggtac
     6541 cggttttcag gttgcgtagc tccagttggc cactggcgct gtggatagcc aaccatccgg
     6601 tatctgcctg ttgaaataac gtatattttt ttaccgccgg aatgatttct tcttttgtgc
     6661 tgccaagggt gatgaccagc agactgttgt ccggcagttt ggtgactgcc agtttactgt
     6721 cagccgtaaa agtgatgggt tggaaagctt tcagtgcttt tttccaggaa tgaccgatag
     6781 cctgtatgat ttgcgttgcc tgtccgggcg gctgattgta gatgtagtag gacgcatacc
     6841 ggccatcgtt gctgatgaca gggttgaggg ccaggctcca ggtattgaaa tcggagtcgt
     6901 tgagcggacg tttctgcgcg taggtgctga tggtgagcag caccaggaag acggctgggt
     6961 atagtctcat gggtggcgat aggattaagg ggggagatgt cccggcagac agctcctgta
     7021 ttcgtggaaa gcatttttac gtttcgtggc gttacctcag ttctgtgggt tgtctgtaat
     7081 aaacaccttt gagcagggct gaccgggaac agtggtggcg ttggcgccgt tatggtcggg
     7141 gccgggaatt tctttcccgg tgagggtgtg atcgcatacg tcctcattgt catacggaac
     7201 atatatcctg tggttgacac gggctttgga agccacgacg cctgcaatga cggagataat
     7261 gaaaacggca gataacaata aagctgactt tttcataata atggattttg aggatgataa
     7321 catcaggtat tttatcttct tcgttggcct ggcagggaat gagggatctt actgcaatga
     7381 taactatttg aggctgataa tattttgtaa agtggtaacc gaaaccgttg atagcgcagg
     7441 agaggtgcgt ggtaatttat ccggatgata ttgcggaatc aaattatcct atggccgctc
     7501 gcatcatagg cgaaacaatc gacgcaaata tggtaaagcc atggtatgac tggcttcagg
     7561 aaaagtgccc ggggtattcg cctcaaaacg tctgcttctt ctccaggtcc ggcagcaccg
     7621 catctatcct tttcgccagt tcaggcagtt taatcgttgg tacggcgggg aacaggtgat
     7681 gctccaggtg gtagaacatg ctgaatgtca gcttgttttt ccaggtgccg cgctgggtac
     7741 gggccagttc cggggtttcg gtggtgtcgt gatgcacggt ccatacggca aagaaggcca
     7801 tcaggcattc gccggtgagc atgacaatta tatggtagat caggaagtgg aggtcgagga
     7861 ggaaaacggt ggtcgcaaat accgtgatgg cgctgagttc caacagggta ttacgcacat
     7921 attttttgtt ggccgtctgc agggtcacgc ggtgaatgtg gaacatatgt acagggccat
     7981 acaggatggc accgtaccag ctcatactgg cagatttacc ttcatagtct tcttcggaca
     8041 gacagtattt atggtggcgg atgtggttgt acttaacggc attcatagag gccatcatga
     8101 ggacgctgtt gagaaagagg gacagccatg taaggcgttt atgggtgccg agtgactggt
     8161 ggaagccgtt gtgtacctgc cttaatgctg tcaggaagaa aaaagccgaa aacgggaggg
     8221 cggcgaggta gtatcccttc catgccagta cccaggaaac cagtagccag gggatggtca
     8281 ggttgttttc aatcagcatt tccgggacgg tcaggtgccg gaggtccttc cagtcgactt
     8341 tgcgttgaat gtcagtatga ttcatgggat acagggttat ccggtacaaa tatacgccat
     8401 cggcaagcag gttgatcagt ttgcccgtaa aaaccaaaga aaccggggga aaattttttt
     8461 ttcttgataa attatttatc ttcaaaaaat caaagtctca aaatagcccg ttactatatg
     8521 tctatgttca acttatataa atccaaatct gaatctgcaa attcccatca tttttaagtc
     8581 tgtacgctga atatccgccc cagggcgtta ccgcttggtt aaagacaggg gagggcctta
     8641 tgaaactgta ttagttatga aaaagaaaaa aattgacctg gcaaaaaaac tgaccctcgc
     8701 caaagaaaca gtggctaccc tgactgtaaa acaaaaagaa gcagtaaaag gtggtgaaac
     8761 ggtgttttgt gacacttacg acccggcctg gacttgcgaa tcaaatcccc gtcccacaaa
     8821 tgtttgcatg tagtaatggc tgttaacccg gcatcaacga tggtaaatcc gatttaaccc
     8881 gtaaatccct ggtatgagaa aaaagaaaat ttccctcggc aagaaattgt ccctcaacaa
     8941 ggcaactgtt gctacgatga ctatccggca gcaagctgtt ataggtggcg gtccgtttac
     9001 ggttatgccc cgttgcattg aaacggtggc acaaacctgt atcacctata tgcccggcca
     9061 ggatcagtgc tacatatgtc ctgaaggcta actttaaaca ggtaataccc ccgttaagga
     9121 agggtatgcc ctccctcaaa tgcactaagt atgaaaaaga aacaaatcgt tctcagtaaa
     9181 aagctattgc tgagaaaaga tactgtcgca tcgctgaacg tgcaacagca agccaaaatc
     9241 gccggtggtg ttccgttaac atggtggagc gcctgttgtc agaatacccg tgaggttacg
     9301 tgccctgaag gatgcgtccg tacttctgaa ccgaaataat tcagcttttg aacccggaca
     9361 caccatccgt tgtaccgcgg acggcggaga cggtgtccac cctaaaacct ccacaattat
     9421 gaaaaagaaa acacttcaac tgagcaaaaa actgctgctc aaaaaagaca ccctcgtaac
     9481 cctgaatcaa caggatcagg caaaactcgc cggtggggct ccgctcacct ggtggagcgc
     9541 atgttgcgtg gaaactgatg aagtgacctg ccctgcaggt tgtgtaagaa caaccaaata
     9601 atcatgatag ctgaacatcc gccccatggc tacagacagg ggagggcttt atttttttta
     9661 tccatcaata tgaaaaagaa aaaaatcgat ctcagcaaaa aactggcgct gaacaaggaa
     9721 actgtcgcat cattgaacat atcccagcag cagcaactgg tgggaggcgt cgctacgcgc
     9781 gatatcgttt gcatggaaga tacacggtat atctccagct gcagagctac gcgcccgtcg
     9841 cctaactcac cctgctgcca gataccctga tggtaaaagg gtattggtca ccggatgacc
     9901 agggaacaac tcctgcatga gcacacccct gtctccgttc ttttcccaac agggaaagcc
     9961 cgtctttccc tgttgtacac tattaaacct ctgctgacaa atgaataata ccgcgacaca
    10021 gttaagatac atctatcatg atatcatccc cctgttaaag gaacgtaaat acaaagccga
    10081 ttataacacc agcctgttca aaggtccctg gggcgcactg ttgtttatgt tctactacga
    10141 acagtatgcg gatgatcagg cggataacgc caccgcactg ctggaggaac tatatgctga
    10201 atacgcacct gaaaaaggag ataattatgc cttctgtaac ggccataccg gcccgttctg
    10261 gctgctggaa caccttaccc gccatgaatt cctggacctc gacatcaatg aactggccag
    10321 cgatttcgtg actgctacta tcctgcaaag caatttccac ctggaacacc aaaactacga
    10381 cttccttcat ggtagctccg gcatgtgcaa cttcctgctg aggtttgcca gccgccccga
    10441 tgttgccgaa cacctcggac attttgttca aaagctgtgg gacaacagcg tgatgaccga
    10501 caaaggccgc agcctgccct tcttctatac acatgataaa cccgaaggta tcttctgcaa
    10561 ttccttcagc ctcgcccacg ggtcctgctc cctcctgatt attgtagcaa aaatatacga
    10621 ggccggtatc gccaaagaac gatgccaaag cctgatcaca gaatctattc cttttatcct
    10681 ccaaaaccag aatgccgttt cggacgattc catgcacgcc ctctaccctg ccatcctgga
    10741 cgggaaatcc accgacagcc gcctctcctg gtgctatggc gacctgaacg tagccatgat
    10801 gctgtggcat tgtggaaaag tgtttggtga agaacattgg aaagaagaag cgctgcacat
    10861 catgcgttac aatatgcgcc gcgacacgga cgaagccgcc ggcatcgtag acaactgcct
    10921 ttgccacggt tccggcggta tcgccgcctt ctaccgcaaa ttctggttcg aaacaggaga
    10981 cgaagctttc ctccgttgcg ctaaccactg gcaggaaaaa gcaaccgaaa aaatcgtctt
    11041 ccccgaagac cacagtaaac acggtatcaa aatgtggctg ggtaaagaca aacagtggga
    11101 atacgtatgg gacctgctcg acggtagcag tggcgtagga ttgtctatgt tgtcccaaat
    11161 gcacccgcag gcgctgccat gggacgagtg cttcctgctc tcctgaaaat tattttaatc
    11221 atctgcaaaa aggaactatt atggccttat cgcatacagg gtttttccta ttaagaagcc
    11281 cgctataccc ggtcaaccgg tatcgtgacg tgctggagga cagcctccag gagctggcag
    11341 acaagaatcc gctgttcctg tatgccctgt gcattgcctc cggcgacctg ctcaaagagc
    11401 tggaaaggtt cctcagtgat ccggcgtcgt tcaacaaaaa gaagaccgac aaactgcgta
    11461 agtcactgta taaatactgg gtacgtgcct gctcccgcag cacgccctat ggcctcttcg
    11521 ccggctgcac caccggcgcc atcggcgccg atacacagct gcggatcaat gacgtgaaag
    11581 acgcctatca gtatgtgcgc ctcgacatgg actattacac ccgcatctgc tatcacatca
    11641 gccagcaggc ggatatcagt accgccttac gctactatcc caacaacagc atctataaaa
    11701 caggggataa ataccgctac gcggaatata ccatcaacaa taaccggcgc aaatacctgc
    11761 tcaccgccgt ggaagactcg gtatttatga gcgccatcat ccgcgaagcc gccgccggcc
    11821 tgacgatcac acagatcgtg caggtgatcc acgagcagga cccctccatc acagaagaag
    11881 aagcgaccag cttcgtccgc gaactgatcg attcccaact gcttatcgca gataccgagc
    11941 cccggattac aggagaagat aacctgcaat ccctcacaga ccgcctttta tccatccccg
    12001 acgccaatac cttccgtgac gcactgcttg cactacaggc actattccgg cagcaggact
    12061 tcgaaaggtc ccgcctggcc gccatccatc aacagtgcga aaacgctttc cccatcagca
    12121 tccctaaaga cctgctgcag atagacctgt ttaaaaccgc tcaacaatgc cagttgagcg
    12181 aaacactggt caacgatatc ctgtcacaga tccatcggtt gatggctctc tgccacggct
    12241 atacgaaagg gcagacggaa ctgtcctctt tcattacccg tttcatggaa cgctatgaat
    12301 cgcaggaggt accgctcaac ctggtgctgg atggagaaac aggcatcggc tacggcgccg
    12361 ccatcgaaaa caccgtacat gcccccttcg tggaagacgt ggccggcgcc cccggcgcgg
    12421 aaaaccagac ggtgtcctgg tcaccactgc agcaactcag tctcgataaa tacgaacagt
    12481 tccttcagca gggcctctcc gaagtgacga tcaccgacga tgacctgcag aaactcggcg
    12541 accctgaaac cgtgcccatg gcacgcagct gctacctctt cggcagcctg caggccgctt
    12601 ctgccgaagc ggcagacaaa ggcgaatacc agttcgccct caactccatg ggcggcccct
    12661 ccgcagccaa cctgctgggc cgcttctgta acggcgacga ggtgctgacg gaaaaagtaa
    12721 aaagtatcct cgatgaggaa gccgccgcct tccccgatct cctgctcgcg gaagtagtgc
    12781 acttcccgga agcccgcgcg gccaacgtat tgatacggcc cacgctacgc ccctacgaaa
    12841 taccctacat cggcgtggcc ggcaccccgg aagaataccg cataccggta aacgacctcc
    12901 tggtgtccgt cagacaaaat gaggtcattc tccgaagtaa gcggctcaac aaacgggtaa
    12961 taccccgcct gagctccgct cataactacg gctataacag cctgcccatc tataagttcc
    13021 tctgcgacct gcaacatcag tccgtgatgt catacctgag ctgggactgg ggggtgttcg
    13081 gcaaccgtaa acgcctgccc cgggtagtct ataaaaacat catcctcagc aaagccacct
    13141 ggacgctcac cgccaaagaa acagcacacc tcggtgatga tgcggaagcc aaccagcgct
    13201 ttatggacca gtaccgcgaa cagcagaaaa tgccggaaaa agtactgctc gccgagtcag
    13261 acaatgaact gctgctggac ctgacagcac ccgctgcagt gggactgctg ctcgaccacg
    13321 taaagaaaat gtcgtcggta aaactgaaag aatgcctgct ggcagaagaa agcggtatcg
    13381 tacgcgatac agacgaccag gcctatgcac atgaactgct gctgccgcta cgttccgtgc
    13441 ctgtcgcgga aaaaacagcc gctgagaaac ctgctgcgga gaagccgcgg cctgctgcta
    13501 tagcggcgcc ggccaccatg ccggtacgta gtttcgctcc cggcagtgaa tggctgtacg
    13561 taaaagtcta ttgcggtttc cgcgtagcgg aagaactgct ggccacctgg ttcgcggagc
    13621 agttaccgca atggcaggaa gaaggcctgt tcgatgaatt ctttttcctc cgctacggcg
    13681 atccgctgcc acatatccgc ctccgtttcc gcaaccacca gcgcagcaac aacgatgtgg
    13741 tcctgcaccg tatccagaca gggctgcaac cgctggtaga caacggacag gtgtctaaaa
    13801 tccaatgcga tacctacatc cgtgagctgg aacgctacgg cagcgccacc atgcatctca
    13861 gcgaacaact gttcagcgcc gacagtatgg cggtactggg cgtcgtcagc atgctggaag
    13921 gggcagaagg agaagactac cgctggcgca tggccctgcg tggcaccgat atgctgctgg
    13981 aagatttcgg cctcaccccc acagaacgca aacagctgct ggccggcctg cgggaagggt
    14041 ttaccacaga attcggcggc gcgaaaacac aacacaaacc actcaacgat aaataccgta
    14101 aacaccagca ggaaatcgcc tccttcctgc gcgccgaaaa tgacgaggcc aacgatatcg
    14161 ccgaagcagt ggaattcttc cggcaacggt cggaaataac cgccccggtg gcgcagcaga
    14221 tacggcagca ttaccagaac gataaccgct atttcgatat cctggccagc catatccata
    14281 tgttcctcaa caggatattc gtagccaaac aacgcaaaca cgaaatggtg atctatcatt
    14341 ttctggagaa atactattta tcacaactgg cgatggaagc aacactgaaa taaatggctt
    14401 ttactactta tagacaactg gacgcgatgg actgcgggcc tacctgcctg cggatggtgg
    14461 ctaaacatta cggccgcgaa tatccgctcg actacctgcg cgaactggcc aatatcaccc
    14521 gggaaggcgt aagcctcctc gggatcagtg aagcagcaga aaagataggc ttccgcacca
    14581 acgccgtgaa gatcacattc gaacagctgg acgagaacgt ggagctgccc tgtattttac
    14641 actggaacca gcaacacttc gtagtgctgc ccccgcagaa ctacaaccgg cataacccta
    14701 aagacaaaat actggtggcc gatccgggcc atggcctcgt caaagtggac aaggaaacat
    14761 tcctccactg ctggcaggga aaacaaaacc acggcgtggt actgatgctg gaaccgggag
    14821 aacagttcct ccggcaggaa gggccccaac gcgcggccac cggcttccgc tttctgttca
    14881 gctacctgcg cccataccgc aagtacgtgg tacagctctt tctgggcctc attctcgcca
    14941 gcctcctgtc gctcatcatg cctttcctga cacagagcct ggtagactac ggcatcaacc
    15001 gccacaatgt acacttcgta tacctgatac tgatatccca actggtgctt ttcgccggct
    15061 ccacggccat cgagatgatc cgaagctgga tactgctgca catgaacagc cgtatcaaca
    15121 tcaacatcat ctcagatttc ctcattaaac tgatgaaact gcccatccgc tttttcgaca
    15181 gtaaaatgat cggtgatatc caccagcgca tcggcgacca tacccgcatc cagaacttcc
    15241 tgaccggcac caccctgtct accctgttct cttttgtgaa cctgctcgtg tttacagccg
    15301 tactggcggt atacagcatg aagatattat tggtgttcgt cctcttcagc accgcggccg
    15361 tcggctggat cttctttttc ctgcgccgcc gtaaagcact ggactaccgg cgcttccagc
    15421 gtatgagcga caacgaaaat gttctcttcg aactcattac cggtatgcag gagatcaaac
    15481 tgaataactg cgaaacagcc cggcgctggg aatgggaaca cgttcaggct ggcctctacc
    15541 ggatcaacgt aaaaagcctc gcgctgggac aataccagca gataggctcc gttttcttca
    15601 accagctgaa aaatatcctg atctctttca tcagcgcccg ggaagtcatg aacggaaacc
    15661 ttacccttgg catgatgctg tctgtcagct atatcatcgg gcagatgaac agcccgctgg
    15721 accagctgct gaccttcatc cagtccgccc aggacgccaa aatgagcctg gacaggctgg
    15781 gagagataca caaccgccag gaagaagaga aacgggaact gatagcgccc ccgtcatccc
    15841 ggtcggacgg cagcggcgat atcgtgctcg aaaacttatc gttccaatat ggcggcgcta
    15901 agtcgccttt tgtactgaaa gacatcgacc tggtagtgcc tgaaggaaaa gtgaccgcca
    15961 tcgtgggcac cagcggcagt ggtaaaacca ccctcatgaa gctgctgctg cagttttacg
    16021 aacctaccag cggacagata aggatagggg agcaggacct gcaacagctg tcgcccaaat
    16081 ggtggcgccg ccagtgcggc aacgtgatgc aggacggctt catcttctcc ggcagcatcg
    16141 ccaaaaacat cgccatcagc gacgaaacca tcaataacga caagctggtg cacgccgccg
    16201 aaatggccaa tatccgcgac tttatcgaag acctgccgct gggctatcag accaaaatcg
    16261 gtaacgccgg cagcggtatc agcgccggcc agaaacaacg gatacagatc gcccgcgcca
    16321 tttacaaaaa tccgcattac cttttcttcg atgaggccac cagcgcgctg gacgctaaca
    16381 acgaacgggt gatcatggac aacctggagc agttcttccg cgggaagacc gtcgtggtga
    16441 tcgcccaccg cctcagcacc gtcaaacacg cagaccagat cattgtgctg gacagggggc
    16501 gcatcgtgga aaccggcaat catgccacgc tcaccgcccg gaagggcaac tattttgaac
    16561 tggtaaaaaa tcaactggaa ctgggaggat aatgtcatgc cggagaaaaa aacgatacaa
    16621 cacctcaacg gccatacgct gcatccctcc ctcaccgagg tgaggagcga agaagtgcag
    16681 gagatcatgg ggaagatgcc cccctggatg gtccgcagcg gtatcaccat gataggcatc
    16741 gcgatggtgc tggccctcgt cggcgcctgg ttcttccgtt accccgatgt gctgcccatg
    16801 cccgtcaggg ttacgccgca ggaacggtcc tttatcgtgc aggggcatat ccctgccgct
    16861 gacgcctggc gggtgaaggc cggccagcag gtgatgctga gcctcaccgc ttacccgtcg
    16921 gacacctacg gcctgctgcc cggtaccgtt accaccgacg cggtggcgga aacagacagt
    16981 agcttccggg tagaagtaaa actcacacaa ggcatgttgt ctaccagcgg aaaacaaata
    17041 ccggtgcaac cggtactgac aggcaccgct gaaattatga cagatgataa aagcctgctg
    17101 caacggatac tgggtaaggc cctggcgccc ctgatgacgg attgatccgc catcagggcg
    17161 cgtttgaccg ctcttgtaga tgttttgtag atactttttt taacgacttg tagatgtcat
    17221 gttacccctg gaattgcgca aaccccgtaa agtttgtcat ctttgtggct gtttaaccag
    17281 accatgatcg gatgaaaaac aagattgtac tgttagtagg ttgcctgatt acaaagattg
    17341 ttattgcccg gcaagccatc gttgctttta ttcccgatga aagtatccgc gctatcggcc
    17401 tgtttaccga aggcctggcc tgggccagta caggcgacgg taattacggt tatttagaca
    17461 ccaccggtaa gatggtcatt gcgccgaagt tccgggaagc cgggattttc agtgaaggcc
    17521 tggcccttgt gggacagtcg gtcaacggta atatgcgcta cgggtatgtc aaccgtcagg
    17581 gtcgcctcgt catcccctgt caatatgatg acgctcacaa cttctcttgt gggcgcgctg
    17641 ccgtcagaac aaaaggcgta tggtcgtata tcgaccgcca ggggaaaacg gcttttgtcc
    17701 gcatggacac ccccatcgaa aatgctccgc cgctttcttt tcacaacggc cgcctgctgg
    17761 tgcgcaaagg gaaactatat ggttttgtag atacctcggg tcgctgggcg gtcccgccaa
    17821 ccttcgcctg ggcaaaggaa tttgctgacg gcgtggcagt agtggccgga aaagagatca
    17881 aaagcgacag catgcccggc aacgggcaac tggcacagct atacaaccgc ctgcctgccg
    17941 gtaaaccgga atatatgacc aatgttatcg atagtaccgg taaactgctc ttcaccacag
    18001 acgtgaaagg actgaaagaa tttaccaacg gcgtatcctt tttcctccgg gacgaccagt
    18061 gggggctaat ggataaaacc ggtaaaatcc tgatggtgcc cacctttgac gatctgccct
    18121 atgccatctc atccggcgtt tttttcaaac aggtgaacgg aacagcagaa ggtaacaaag
    18181 acggctacct gcaaatttat aatacagcag gccggcccac cggcaaaatg ccgctgtgtg
    18241 acgcagcagg gaattgtatg tacgattccc acggcgctta ccacagcaat ctgctggcgg
    18301 tacagattgg agacaactgg ggctttgcag acacctccgg aaaaatagtg atcgccccgg
    18361 tatataaaac agtatcagac ttcgcaggta cgcacgccgt ggtgaaaacg gccgacggaa
    18421 aactgcaggt actgcgtaac cccgcgctat agaagatcag cacctattgt agatatgaag
    18481 aagagaacat ttgttatccg cctcgccggc agcctgctcc tgctcgccgg gacagccctg
    18541 gcccaaacac cggaaacagc aggatacctc gaccgcttcg agggcgagtt cgcaaaaatc
    18601 cagctcaacg gccgccaaca gttgctgcac cgcagcggca aagtggtagt ggacaaaata
    18661 caggaattga gctactaccg gctggtatcg gcagtcaaac aggatgctta cggcgtagtg
    18721 aacagaaaag gagatattat agctccgttc cgctacgacg cggtacggat actgggagaa
    18781 agcaaacagg acaaccccgc cgaaaattac tgccttatca ccgtaaaact gcaaggaaaa
    18841 acaggcgcga tagatagcct gggcaaggtg ctctgcgagc cggaatacag cgatatcggc
    18901 gtccttaccc ctaaaacctt cagcatcaaa aaaaacggac tgtatggctg gtgtgatatg
    18961 aagaccggca aagtcttaca ggaaccgaaa tatacagaag tgtcgcgctc ctatgtggtc
    19021 gatggcctga tcaatatcca gttacagggc aaaagcggcc tgtcacagga agacggtacc
    19081 atcctggtac cgccgaaata tgaacgtttt atgggctgga acagccggca actgttcagt
    19141 tactatgtac ccggcggaaa gtgcggcctg atggaccgcc agggaaaagt gctgacacct
    19201 gctatctatg acgatatcaa tgcaggaccc tccgatgcgc tggtggccgt gaaagtgcag
    19261 gacaaaacag gtctgctgga cgtggccacc ggccaactga aaacgcccat gctgtatacg
    19321 cgggcggacc gccttggccc actgttcacg gtctggaaag gcaacctttg cggattgaca
    19381 gacgcgctgg gtaaagaaat catcccggta gcccacacag atctccagtt gtttgacagt
    19441 aaaggccata acgttttagg ggccgtggtc tcactgggcc cctcatcagc agggtatacc
    19501 ccgccttatt atgtggtggc gaagaaaggt aatacggccg cgttttacga cgccgccggc
    19561 aaacaactgc tgccctttga atatgacgat atccgggtaa catcgcggaa tgacaaggca
    19621 tacgtgtcgc tgctgaaagg cactcagtgc ggtttggcgg atatatccgg caaaatcatc
    19681 gtgccggtgc agttctccgg gattgacaat aactatggca tcagtaacta tgacgacgat
    19741 gctgccggca cggagaaaaa taacttcatc gccgtgttga aagtcatccg ggaaggggtg
    19801 atcggcatag gtttgtttaa tatggcgacc gggcaactgg tgattcccgc cgtctactcc
    19861 ggcctccgct ggcagaatga caatatgatc cggctggagc agggcgatag ttccggcctc
    19921 gcagacaaaa ccggtagaat catccgcccg ctgaagaaat acggcgcgtt cgatgcggtc
    19981 agtccggatc tcatcgtgga aaaacgttat tacgatgacg gcagtgccac gctgctcgtg
    20041 aacaaagagg ggcgggtact gtatgatagt aaacactggg agttctccgc tactgcctcc
    20101 aaccggctgc tggtaccgga tgcccggaaa acgtggccgt tacaattcaa cagcgggctg
    20161 ctgaaagtac ggggctactc ctacgaaaac cagtttgtag acaccacggg taaactgatg
    20221 gcattcgaag aatacaagta tgtaggcgat ttttataacc gcagggccgt ggctattacg
    20281 caagatgatc gcgtggggat catcagcatc gataaaaaag tagtatatcc gttggagtta
    20341 gatgacctga cgtccgcgga caatgagctg ctgaaaatga agcagggtaa aaaagttggt
    20401 ttgctgcgca aagacggctc cgttttcctg cccctggagt atgatcatat cgaccgggtg
    20461 tatgataccg ccctttatat tgtcacccgt cagggtaaaa agggtgtgct gaatgcggaa
    20521 ggtaaggagc tggtgccggc ggattatgat gaaatccgct acagtaggga cgacaggatg
    20581 ttcgaggtaa caaaagacga taaagaagga ttgctggggg ccgatggcag catcctggta
    20641 ccacctgtat acgacgacct ggagcaaaac cggacctggg gagatcattc gaagttcccg
    20701 gtactggtaa aacagggaga atggtacctg tatcttgatg cacaggggaa accgttgcct
    20761 tatcgcgcta aaaagaaaaa aggctataat gaataaaaag atcatcttct tcatagccct
    20821 gctgctggcg gggcataccc tgccggcaca gcaaggctcc gtcttcacca acggactcgc
    20881 ccgcattgtc acaaaggaga aaagctggtt tattgatacc accggtcaga aagtgtttga
    20941 taagattgta gccgtctatc atccggtgga cagcattgtg gaaggaagca tctactccaa
    21001 cacggaaaag aatatgctga tcgtcagcag taatggtaaa aaagggctcg taaatgaaaa
    21061 agggcaatgg gtattgaagc cggagtatga tacgctggaa gtgagattca atacctatct
    21121 ggcagtatat cgacaaggta agatgaccta cgcggatacc tggggtaaac tcctggtgcc
    21181 gctgcagttt gagcaggtag gtatcctgga tgacgaccgt tacgatgtga aacaacaagg
    21241 gaaatggggt atctatgatg tacgccggca acagctggtg atcccggcag tatacgatga
    21301 gtttgactac tgcggtggct gcgggcgtaa aagcgactat ctctatgcaa agaaaaacgg
    21361 ccggtggggc atcatcagcg ctgccaacga agaactggtg ccttttgcct tcgaccacag
    21421 tcactcccgg atgcgcagcg atgaatgggt atgcagtttc cgacagaacg gtaaagacgt
    21481 ggtggttaac atcccccgga aaaaagtata tggggagccg ttatacagtc agatggaagt
    21541 gatcggcgac ggtatgctga aactacagaa agacggtcat ttcggactta ttaaccgcca
    21601 gggggagcaa gtgctggatt ttgtatatga cgacattagc gatccctatg ggcagttcgc
    21661 cagtggccct ttcctgacca tccggaaaga aggcaagacc ggcatcgtgg atatgaatgg
    21721 ccggatggtc ataccacctt cgctggatga agaaatcatc tgttcagatg actatatcgt
    21781 agccgcgcgg aacggtatgt acaatgtatt tgatagtgcc ggtaagcctt tgctgaaaga
    21841 ggactatagc gagatagaac cgctgaagat aacaggaggc gcaccgcttt ttgcgctcaa
    21901 acaaaaagcg ctgtatggtt tttttaaccc cgtcaacgga aagatagtag cgccggcatt
    21961 tcacgagata gacgtcatct cctccggcaa aagcaagggg atggtacagg tcacctacca
    22021 gggtaagtcc gggctgtaca gacccgacgg cagccagctg ctgcccctga aatacagcag
    22081 ctatgagctg ctgaacgatc atgttttgat ggtgaccaca ggcgccggca ccggcctttt
    22141 tgatgccaat acccgagagg agattattcc ggcaaaattc aaatacatga gccggttgtc
    22201 ccaggacagc acgctgctga gcgttacatc ggaaaatgaa tcgggtgacc ctgtctacgg
    22261 cctttaccat atctcaggta aagaactggc gccaccggtg tatacctaca tcagcgcgtt
    22321 aaaccaggaa cattacctgt tgacaaaaga aaaaacacat gcggtcctct cgctgtcaac
    22381 cggtaagatc gctgccttgc cttacaccga cgttgttcct gcacatgcgg ccaatctcct
    22441 ggtggtgtca gatggccgcc agtcctggct ttggaatgtg gtggaaaata aaaccgtatc
    22501 cccgcctttt cccatggtga ggaaatatga agacgatacc gtactgacgt cccccattgg
    22561 cacctttgcc ttcggggtgg cgctgctgga aaaaaatggc aagatgggcg ttatcaatac
    22621 cagtggcaag gaagtggtac ctgttattta tgacggcgcg tccctgctga aacagggcgt
    22681 tgttctcctg gcccgcaaaa atggcgacgc ctggaaatac gggtatgtgg atacgaccgg
    22741 taaactactg gtaccgctgg aatatgatta taacgtgaac ggctatatct atgattatga
    22801 agacagcact tatttgccgc tgtataaatc ggagggcggt tactcacgcg cctataaaaa
    22861 aggaatagcc ggccgggacg ggaaagtgct ggtccctgct atctacgaca gagtatttgt
    22921 aggtattggc ggcaccggtt ttttagcgga caaagaccgg cagtttacca tcctgaatgc
    22981 cgccggcaag gaagttactt ccgctaaatt ctccgctgtt atgctggacc cttctgtgaa
    23041 tccgcaggca gatgccgcag tgttgtccta tccgttgtta tgccggcagg gagagcggta
    23101 tgtatacctg ttgtccaacg ggaaaacgtt gccgttgcaa ctaacagcag taattcggtt
    23161 tgaggagttc gacaatacga tcgggtacca tccataaaag cagatccata aaaaagccgc
    23221 tgtacatggt gtacagcgga ttttttatgg atctgttttc ccggccggct gcggcgaggc
    23281 gtatttaagc cgcggataat aagctttaaa aaggtccgct ggctccggtg tatctgattg
    23341 catagacata gctgctccct tgctgactgt ttactaatag cgctgcctgg atagcgcagt
    23401 gataacttac atataaaatc gcaaaaaagt aaacaaatac ccattatctt cgaagtctaa
    23461 ctacgagttg acttttttat gaagtttacg ttcattattt ttattgccag ctggatgttc
    23521 gtcaccgcct ccgtgcaaaa gaaggggccg aatgtgatca caacagatat tgacaacttc
    23581 tggaatgcct atgacagcat ctgtattaca acagatagcc tgaaacagct gcattatatc
    23641 cggacgctgt atatcgataa gggcacgccc ggtttgcacg ggtttatgaa agccaaagca
    23701 tatacagccg aagagtgggt gaaagtcatc cgccgttacc ctaagttttg gcgttctata
    23761 cggagtaaca cttacaaggt taaaaaactg gcgccggagt tcgggcccgg tattgacagg
    23821 ctgcgggagt tatatcctgc tttaaaaccg gccaacatct atttcacagt gggcgccctg
    23881 cgttccggcg gcactacgca agacgacatg gtgctgattg gcagtgagat gataaccggc
    23941 aatgctacaa cagacatctc tgaattttct cccggaaaac aaaaattcct cggcaactac
    24001 tatctcacag atcccataaa aaatgctgtt ctgcttaata ttcacgagta cgtacatacg
    24061 cagcagcgcc gccacggcta taatctcttg tcgcaggcga tttgcgaagg agcgtgtgac
    24121 ttcgtaactg aactggtgac aggaaaaaag atgccgcttc cttatatgga ctacggtctt
    24181 aaaaacgcac aggcggtccg gaagaagttc ctggcggaga tgcataatcc ctcctgggac
    24241 ggctggttat ataacgctgc gtcagacaat gcgcccgtag gcgatttggg ttattatgtg
    24301 ggatacgcta tctgcaaggc ctactacgat cagcaaaaag ataaaaaagc ggccgttcgt
    24361 gagatcattg agctggacta tggcgacagc acg
//
