LOCUS       NZ_FUWZ01000001        20996 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga eiseniae strain DSM 22224, whole genome shotgun
            sequence.
ACCESSION   NZ_FUWZ01000001
VERSION     NZ_FUWZ01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga eiseniae
  ORGANISM  Chitinophaga eiseniae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900167135.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 16:06:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,843
            CDSs (total)                      :: 6,771
            Genes (coding)                    :: 6,741
            CDSs (with protein)               :: 6,741
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 2 of 30
            Pseudo Genes (incomplete)         :: 28 of 30
            Pseudo Genes (internal stop)      :: 1 of 30
            Pseudo Genes (multiple problems)  :: 1 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:38:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1051778
            Orig. end                         :: 1072774
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FUWZ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20996
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20996
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20996
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10996](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10996)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    158..176
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.97"
                     /tool="antismash"
     gene            complement(906..1568)
                     /locus_tag="B5D63_RS04460"
                     /old_locus_tag="SAMN04488128_101903"
     CDS             complement(906..1568)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012257.5"
                     /locus_tag="B5D63_RS04460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101903"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_159455883.1"
                     /transl_table=11
                     /translation="MSQLTMIHTNRAILTFIENQLTETEKKDRVFLQTWPAGGHLLKQG
                     QGNKYVFVQQTGLSKVHITEDNGKDFIVQFLGEGELLGEIEVIQKTLNLTTVTALTEVT
                     AWCITTDYFAYLITHNAELNRLLLLSLAHRLNQTSARASYQQVYPAEYAILKLLSVLAT
                     QQTNFAKKDLADYLGVSVRSFNRSLKQLRERSIVHPDSFDLYIDRDVFERLMREYGE"
     misc_feature    1559..1578
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 22.86"
                     /tool="antismash"
     misc_feature    1600..1614
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.88"
                     /tool="antismash"
     misc_feature    complement(1610..1624)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.19"
                     /tool="antismash"
     gene            1624..2316
                     /locus_tag="B5D63_RS04465"
                     /old_locus_tag="SAMN04488128_101904"
     CDS             1624..2316
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018611493.1"
                     /locus_tag="B5D63_RS04465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101904"
                     /product="HAD family hydrolase"
                     /protein_id="WP_078668540.1"
                     /sec_met_domain="HAD_2 (E-value: 6.3e-16, bitscore: 55.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGIQTIAFDADDTLWVNEPYFREVENKFCGLLEDYLPHHTVAQE
                     LFKTEMQNLPLYGYGVKAFMLAMIETILRVTENNASPALIAKVLEYGKEQLAKDIELLD
                     GVKEVLDTLKGKYRLVVATKGDLLDQERKLNKSGLAHYFHHIEIMSDKQEKDYRKLLRH
                     LDCSPEAFLMIGNSIKSDILPVLAIGGHAIHIPYHTVWAHEVVEGEVKDERFYSFENIS
                     AILPRLLS"
     gene            2313..2936
                     /locus_tag="B5D63_RS04470"
                     /old_locus_tag="SAMN04488128_101905"
     CDS             2313..2936
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018611490.1"
                     /locus_tag="B5D63_RS04470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101905"
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="WP_078667542.1"
                     /transl_table=11
                     /translation="MKQLLDINTWARKDHYHFFSQFEEPFFGVCVNVDCTRAYYVSKAR
                     GYSFFLYYLHKAMVAMNLTEPFRYRIIDKQVWVYDHIDPSPTINRPDGTFGFAYFPYHA
                     DFETFAATARVETEKVQSSSGLIPAVSGENVVHCSSMPWINFTGLSHARSFTFPDSCPK
                     ISFGKMTDNDGKMTMPVSLHVHHALMDGYHVGLFLEEFQRQLDV"
     gene            3065..3853
                     /locus_tag="B5D63_RS04475"
                     /old_locus_tag="SAMN04488128_101907"
     CDS             3065..3853
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016296.5"
                     /locus_tag="B5D63_RS04475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101907"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_200816912.1"
                     /transl_table=11
                     /translation="MFAVSICTLGMIVANVLLDYWYSWYLERAFYMSESLLFSVYWVMF
                     LPLLPALWWLIERTEKVGLKFAFTGGAIAFHLLAYPALVWVLSKMFYYHTFSFGQTFQF
                     GLSAYFLKSVIVYGFLLLMLTILRKKVVSPPTVREAASSTSYLHALIVADHHHQKQVLA
                     VNDIFCFTACSPYVTIHHLSGNYLYAETLKSLESRLDEIQFVRIHKSHIVNLQKITSYQ
                     SRQNGDYDVFLSDGAVVRASRNYAKAFKSKLERWTQHTVK"
     misc_feature    complement(3905..3920)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.91"
                     /tool="antismash"
     gene            4060..4572
                     /locus_tag="B5D63_RS04480"
                     /old_locus_tag="SAMN04488128_101908"
     CDS             4060..4572
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012976.5"
                     /locus_tag="B5D63_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101908"
                     /product="hypothetical protein"
                     /protein_id="WP_200816913.1"
                     /transl_table=11
                     /translation="MPQKINAVDTSPGWNEEGQQLMVTGTVFQQDGRTPAKDVVIYYWH
                     TDNDGYYSPAPGMDERVKRHGHIRGWVKTGPDGKYAIKTIRPAPYPKDMLPAHIHLSVK
                     EPAVANEYYTDEINFEGDTLLVAHFRKYPPENRGGSGVVKVQLKDGRQVAEHNIVLGLN
                     IPYYPKK"
     misc_feature    4714..4727
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.38"
                     /tool="antismash"
     gene            4763..7732
                     /locus_tag="B5D63_RS04485"
                     /old_locus_tag="SAMN04488128_101909"
     CDS             4763..7732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014218792.1"
                     /locus_tag="B5D63_RS04485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101909"
                     /product="endopygalactorunase"
                     /protein_id="WP_078667544.1"
                     /transl_table=11
                     /translation="MKNIFILLLVILLAGTAKALPAGLPVKIPASAMRAIPLPLPRAQA
                     GPASPHIASIVADTIKVVTGSTVAYTVDTKADEGLVSTATTVAHLLAELQTNVAVQRRQ
                     VTTADGNPKDTGVIQAGDRLILTNPRGSTIYYLLPEQRALTGKLELLRPVVTAQVKNTI
                     TLHYTAGQRSPDATVTIHFPAGITITPENTTVNVIGRGAVLLRDLPGQSIGRTGTRYSY
                     KRVGEAVIEKAADGSTTLTLRHLDLRPANGPDLVLVIQDVMLNDSGRYFINATSTTSQP
                     AVLASSGLAGETADLWVTNTIADFKRVVVKDKPYHELPHDYTQVQFRWTPVTAGKVTME
                     YSTDTGRHWSAAKASIDAAHGTAFITGLRRDKLYHFRLLVKDGVHRGSSNIAGDYTGML
                     DVRMFGVHGNDTADHTAGINEAIRFMHNIGGGTLLFSEGVYNVRTVHLLSNVYLYISKE
                     AVIRAGKGADAPETTWFSDRAYRSGLSPTDRGPYEDPENYLTKQDVGHHYFHNAMFFGE
                     RLDNIKIIGNGRITGNGHLVTSDKVMNNAPDKRADKMFSLKLCTNVEIGGLHRDHDLWY
                     DSVKDVPYYVDKGGLPSYDDSNMLQIDRAGHFVLLATGTDTLFVHDTYFGKMDQANVRD
                     IYDFMACNQVTVRNIYSRVSSDDIVKPGSDCSLGFTRPARHYRVRNVIGDTNCNLFQIG
                     SETADDIMDICVDNIYVLGANKAGFSISTNDGGRVKDIHLNCGHTGPVNQRSRMMRTTA
                     PFFISISNRGRVLGATVGQYTFVEEGRKRTELLVQNVNIGQVENIVINSIDISEVYGGS
                     SFGNGSRWKPFDGSQHRATSIIAGYALPAAGAVEGGLDFTLPDGRHTGYIRNVVFNDVH
                     ITDKGGHPLADTAQRPPELGVGQYNVSNLKVQPSYGLWARHVEGLTISESSFRFEQPDS
                     RYALFLDDVQGAALFGIKTVRAAGDSEWLRYIRSSGVRWKNILFYQEAWGKSPVSAGSR
                     "
     misc_feature    4764..4778
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.47"
                     /tool="antismash"
     gene            complement(7738..8121)
                     /locus_tag="B5D63_RS04490"
                     /old_locus_tag="SAMN04488128_101910"
     CDS             complement(7738..8121)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS04490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_101910"
                     /product="hypothetical protein"
                     /protein_id="WP_078667545.1"
                     /transl_table=11
                     /translation="MNKLLIFSLFLALSPFMAKCQTYKAPTSTNKTYLATIKGITYTYQ
                     NGIITVKNNGQYNIGVLRISATSTGDKELYGVALFEDGLDKGQTLKTTVYFTRGLDNEK
                     EIPLKEINAQKLEFSITMATRAQ"
     gene            8251..10026
                     /locus_tag="B5D63_RS04495"
                     /old_locus_tag="SAMN04488128_101911"
     CDS             8251..10026
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="B5D63_RS04495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101911"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_078667546.1"
                     /transl_table=11
                     /translation="MTYFRLFHPVLLAREIIHTGTAQLEGEEKKRVSIINTLSLASIAL
                     CLIFGTVIYYLTGNLEILLPAYAEALLFVVVLMLNHFRWHNTAAILTAFVHNLSIVYFS
                     ALLGMVTEVYLLFFFLLGAALMVFHGKPLLIKFSIAISVICLVLCELNYYYYFIEPLEL
                     SHYEQFLIRWVTIPAILVLDVLTFALYVRTLRRKNAQLERKATALEMADKATRRQAMET
                     SHEMRNPFNAVYGISQDLLMQVQKSDLYPAELKASIEHLYSASHNVLQILNNNLEHFRQ
                     QEGVAPQLESGAFNVRDWAGEATAIYQYIANVRDVSIALEIDPKMPARLEGDKIKLTQI
                     LNNLLFNAIKFTHANSTVTVQIRPDGRQWQLLVKDSGDGIPPERLSTIFSPYVSEQHAF
                     GGTGLGLPIVQRFVELMGGTIAVTSKTGEGSVFTVNLPLTAVEEAPAPEAPANKNITLQ
                     AFPGVKALVVDDNQMSNMILCRFLERMECSTSAALGGEEGLEKAIATQPDIIFLDSHMP
                     GMDGKATLAALQDNPATHNAIVIIVSGDAAEASIAEMLAAGADDFMTKPIDLKSLNELM
                     IRFEARLTTNSQRNP"
     gene            complement(10001..10996)
                     /locus_tag="B5D63_RS04500"
                     /old_locus_tag="SAMN04488128_101912"
     CDS             complement(10001..10996)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="B5D63_RS04500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101912"
                     /product="hypothetical protein"
                     /protein_id="WP_078667547.1"
                     /sec_met_domain="T1TS (E-value: 5.4e-72, bitscore: 240.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METTTLPGLYCPFPGKLNPLVEKADRHTAAWVRKFGLDNNDGQWQ
                     LYQEQKFTWMVARMFPNADLFRLAIAADFNTLLFLWDDEIDRITLNDPGTSFEALAGKM
                     IGILRGRYQAEPLQDPPLLLAMQDIWRRMVQIGPADWQQRFTTSLQAAFMSNSWRMQHV
                     TAIGSISLEDYMLHRPGIGGANFFLDLAEIMEGIHLPASWYADPLIKDLGLLCSRTICW
                     ANDLFSYTKELEQGDELNLVMMIKNKRQLPLEKAVHEAAAVHDDEIRQFLHTAEILLSL
                     SSGQDYPLLDSYILMLEHMMEGNISWSTKDTSRYGIANQDLRITDYAENL"
     misc_feature    complement(11397..11410)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.65"
                     /tool="antismash"
     gene            11402..12202
                     /locus_tag="B5D63_RS04505"
                     /old_locus_tag="SAMN04488128_101913"
     CDS             11402..12202
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013997.5"
                     /locus_tag="B5D63_RS04505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101913"
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="WP_159455884.1"
                     /transl_table=11
                     /translation="MRFRIKLKATQPAAVIPINYPYALSAVISRILHQADEDYASFLHE
                     KGCAKAGSLKVFKHFSFSEIRTAFRIEGDRFRFLSDEAMFMISFHLPQAAESFIQGLFL
                     GETIEIADRRSQAAFTITEVLPTPTPLEDIPDTAITEVILQPFSPLVCGTKNDRGYYDF
                     LSPQHPDFVKQLVHTWREKFITMYGEEEVDTIFDPVSVEVVMMERPPKSRLVTIKADTP
                     QETKIRGYTNFRLKVKGVGQALKLLADAGAGVYNSAGMGSLHIL"
     gene            12274..12744
                     /locus_tag="B5D63_RS35385"
                     /old_locus_tag="SAMN04488128_101914"
     CDS             12274..12744
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS35385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_101914"
                     /product="hypothetical protein"
                     /protein_id="WP_235021459.1"
                     /transl_table=11
                     /translation="MNRSLLRNRSGIVFTTSSITGGGSTIFLRRPWLSKKITISAFSRE
                     VYKLTIVNNITIIQGLVSLEVKSDHIYMHLVESAPFNKGKMKVYAGVPGNLVAFVCRVS
                     FRRGFDGTVSFLSKTQLIDHYIESLGAIHIGGQRMIIETKAALKLIDKYFKN"
     gene            12749..12931
                     /locus_tag="B5D63_RS04515"
                     /old_locus_tag="SAMN04488128_101915"
     CDS             12749..12931
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B5D63_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488128_101915"
                     /product="hypothetical protein"
                     /protein_id="WP_078667550.1"
                     /transl_table=11
                     /translation="MKHRKVELDVDCIGGVRPLTKEDEKVISEFIKERKDAKGKTGSAA
                     IAGRDRKTVRVKTKS"
     gene            complement(13070..15886)
                     /locus_tag="B5D63_RS04520"
                     /old_locus_tag="SAMN04488128_101916"
     CDS             complement(13070..15886)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014219721.1"
                     /locus_tag="B5D63_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101916"
                     /product="FAD-binding and (Fe-S)-binding domain-containing
                     protein"
                     /protein_id="WP_078667551.1"
                     /transl_table=11
                     /translation="MNIAHELKKILPENRIKSRYIDLISYASDAGFYHLVPQAVVQPIG
                     EAEIVALFRFSQQFRIPLVFRTGGTSLSGQSITDGILVDLSQYWNKIQIEEKGQAVRVQ
                     PGITGAMVNTYLKKHARKIGPDPSSINSAMMGGILSNNSSGMCCGVALNSYHTTRHIRF
                     ILPDGNTFSTEHKKDYARFEMECAPLFVSLADCRDLIAANRALHDRIRHKYQTKNTVGY
                     ALNAFIDYHHPLDIMAHLLIGAEGTLAFIAEAVMDTVPDYAYKSTALLYFPTIYAACQA
                     IVPLTNAGALMVELMDRASLHAVEDMDGMPSIVKTLPETAAALLIEFQEESQAALDARV
                     NGFMASAASLDMSEPPVFTIDPAEQSFFWKIRKGLFPAVGAVRASGTTVILEDIAFPVD
                     KLGDAILDLQQLFAQYHYLNAIIFGHAKDGNIHFVVTQSFNTPDEVTRYELFMQDVVAL
                     VVNKYDGTLKAEHGTGRNMAPFVETEWGGDAYDIMKKVKEAADPHNLLNPGVIINPDAR
                     AHLKHLKELPTVEEEVDRCIECGYCEHKCPSRDITTTPRRRIVIRRALKQLQKNGDKAH
                     YKVLLDQYQYDVLETCAVDGLCATACPVDINTGDLVKRLRRENHSPTANKLALQVARHF
                     RTVEWAARTAIQVGTGINRVFGKHAMTSITKGIRSIIPAVPLWSEQLQPAPGLGILKPQ
                     QSADASIVYFPACISRMLGTYEGKSKNLMETFMSVCRKTGISVVVPDNLSGTCCSQIFS
                     SKGYKDAYEHTANHIIEKLWHDSRQGALPVVIDVSSCAYTLHHVRPALNAANKEKFDQL
                     RILDAVDFLHDFVLPKVTAINKKKSIALHPVCSLEKMKTGPKFVKVAQFFAEEVVVPKY
                     AGCCGMAGDRGFLFPELTASATRPESLEVKCNEHDGYYSSTKTCEIAMSAAVKKNYESV
                     LYLVDEGL"
     gene            16004..18226
                     /locus_tag="B5D63_RS04525"
                     /old_locus_tag="SAMN04488128_101917"
     CDS             16004..18226
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF026255.5"
                     /locus_tag="B5D63_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101917"
                     /product="outer membrane beta-barrel protein"
                     /protein_id="WP_078667552.1"
                     /transl_table=11
                     /translation="MLRCNNLLPVLLLADLFLITPLLTHAQQPAGDTLPAPKVRQLSEI
                     SIIQQKALVERRTDRLIYNVTSSVGAAGANGLEVMARVPGLRVTDNLIAIAGKGAVKVM
                     VNGRIIPLAGEDLQRYLKSMSAGEIARVEVITNPSAAYDADGNAGLINIVTRRDRNQGF
                     SGEIQASGKLSDYGFKKLYGVSNYGTMSAGGNFSYNTRRWSLYGNLNYEHGRFLEGFGI
                     DLQYPNRFWSQTDTGNYKIRNLNLVLGTDYKISNRSTIGFNYSGARTAYIGDDHVNNPV
                     FNTGGLLDSLLRTFATYQPVAWSTGLNLHLVTKLDSSGRQFSVDADYFNYYRTDKSDFI
                     SQRYDRKGEAIANGTTKYFDTNKQAINIYTLKADLQWPTTFANYAFGGKLSFINNYSNV
                     FYFRNLQGEMEYDKNLSNEYDYTENTQAVYATASKEAGRWKLNAGLRMEATQTKGVSHV
                     QDNAMGNNYVKLFPSFSADWNYHNDNHLAFTFGKRINRPVFWDLNPYKSLTTAYSYLEG
                     NPYLQPEYNSNFELSHHWQHRFTAAAFLNITNNGFNRITVATPNNNTVYTTPENFLKIY
                     RYGLSASATLQPLPWLESVNQLSGYHTDARSALPNIPDINGMSVYLATNNNITLNQDKT
                     LMAVLNFWCQFPEVDHNGKSNTYYNMDLGLKAVCLQNRMSIALNGADLFRSSASIVRST
                     VNNIPQTFTHFQVNRQIRLSVSYKLGQSTRKREVRGTGSEEERKRT"
     gene            18559..19170
                     /locus_tag="B5D63_RS04530"
                     /old_locus_tag="SAMN04488128_101918"
     CDS             18559..19170
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="B5D63_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101918"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_078667553.1"
                     /transl_table=11
                     /translation="MAVKKEQDASTEERILAAARIVFTRKGFAATKVRDIAAEADINLS
                     LVNYYFRSKEKLFEVVMAEAVQKLVFEIATIFNDTQLGIPEKITRAVNYYIDLLLENPD
                     FPLFLVNEIITGDDMFTRFAQQNTLFQSDLIRQLFAMKEEGKLSVHPVHVMMNVIGLVV
                     MPFLARPILERNALVKDGEFVKLMNERRTLIPLWLKGMLG"
     misc_feature    19271..19284
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     misc_feature    complement(19272..19285)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            19308..20579
                     /locus_tag="B5D63_RS04535"
                     /old_locus_tag="SAMN04488128_101919"
     CDS             19308..20579
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012790570.1"
                     /locus_tag="B5D63_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488128_101919"
                     /product="TolC family protein"
                     /protein_id="WP_235021460.1"
                     /transl_table=11
                     /translation="MKVCKLLGCIMMLAGLTAEAQQQALTLETCYALARQNYPLIKQYD
                     LIARTSRYTVANAGKLYLPQLTVSGQATYQSEVVNFAEVLPPIPGLNPPQLSKDQYRLQ
                     AEVSQQIYDGGVTRYQQEASRANEKVQQQSLEVSLYAVRERVTQLYFAVLLMDAQLRQN
                     ALRRDNLQSTTDKMKAALANGVAYRSNVAELQAEIVNADMATTEFRANRKAYLKMLATF
                     IHQPLSDSTVLAYPETTRPAEGIHRPELALYDYQQNTYDVQERQLKAAYLPKLNAFLQG
                     GYGRPTLNIVSNEFGSWWMGGLRLNWSIGSLYSLKNNRRLLDIQRSNVDVSQEAFLLNT
                     TLTMQQQHQDVDKYAALMTQDEEAIRLRAAVLQSAKAQLDNGVITVHEYISQVNAENLA
                     KQTRILHEIQLLQAQYNYKNTSGN"
ORIGIN
        1 cagccgtttt tcctgtatct gcctttcccg atgccgcatg caccgctggc ggttccccgg
       61 gagtgggccg gcaaatcacg ggctgggtta tacggagatg tcattgaaca gcaggatgcc
      121 tgcatcggaa aaatcatcgc tttactacgc acgctgaaac tggataaaaa caccattgtg
      181 atgttcacca gcgataacgg accatggaat gccatgcccg accgcatgtt gcagcgtgat
      241 attgtaaaac cgtgggacca cggttccacc gggcctttcc gcgggggcaa ggccaatacc
      301 tacgaagggg ggcaccgtat gccgtttatt gcctgggcgc caggccgtat ccctgccgct
      361 accgaaggag accagccttt tatcatcaat gatatcttac cgacgctggc taccgctacc
      421 ggctatacgc agccgctgcc ggccaacctc gaaggcgtca attgctgggg acacattacc
      481 ggccgccagc cccggctgcc agaaaggccg ctgttttacc tgagtgcggt cgggaaactg
      541 gaaggggtgc gacagggtga ttggaaactg cgtatcgcca ctgtagaaaa agacaaaaca
      601 ccggaagtgg aattgtataa cctgacactg gacaacagcg aaaaacataa cgtggcaggg
      661 aagtatcccg aaatagtatc aacattgaaa cagctgatgg ataaatactg acacctttgt
      721 tgggatagcc tttcgcggtt ttgccggaca tgccctccag cactttctga aaactgatat
      781 cccgttataa tcagtgtttc gccccgggga atacccgggg ttttttatgt tggcttcccg
      841 ggcttacacc cggcgctgcg gtgtcagcgt ctgccggtat ttcaaggctg ttaaagaaag
      901 ttatgctact ccccgtattc ccgcattaac cgctcaaata catcccggtc aatatacaga
      961 tcgaaactat cgggatggac gatacttctt tcccgcagtt gcttaaggga acggttaaaa
     1021 cttctcaccg atacccccag gtagtctgcc aggtctttct tggcaaaatt ggtttgctgt
     1081 gtagcgagga cagataataa cttcagtata gcgtactcag cagggtagac ctgctgatag
     1141 gaggcccggg cggaggtctg attcagccgg tgcgcgaggg acagtaacag gagccggttc
     1201 agctccgcgt tatgcgtgat gaggtaagca aaataatccg tggtgataca ccatgcggtc
     1261 acctccgtca gggcagtcac cgtggtcagg ttaagtgtct tctgaatgac ttctatctct
     1321 cccagcagtt ccccttcgcc caaaaactgg acgataaaat ctttcccgtt gtcttccgtg
     1381 atatgcactt tggaaagccc cgtctgttgc acaaagacat atttattccc ctgcccctgt
     1441 ttgagcaggt ggccgcccgc gggccaggtc tgcagaaata cccggtcctt cttttcggtt
     1501 tccgtcagct ggttttcaat gaatgttaaa atagcgcgat tggtatgtat catggtgagc
     1561 tgggacaaat gtcccgtttt ttcgcagttg aagctattaa ttttacagaa attttcagaa
     1621 tttatgagag gcatacaaac catcgccttc gatgcggatg atacattatg ggtcaatgaa
     1681 ccctatttca gggaggtaga aaacaaattc tgcggtctcc tggaagacta tttgccccat
     1741 cataccgtgg cgcaggaatt atttaaaaca gagatgcaga acctgccgct gtacggttac
     1801 ggcgtaaaag cgttcatgct ggccatgata gaaactattc tgcgagtgac ggaaaacaac
     1861 gccagtcccg cgctgatcgc caaagtgctg gaatacggca aggagcagct ggccaaagac
     1921 atcgaactgc tggacggtgt aaaggaagta cttgataccc tcaaaggcaa ataccggctg
     1981 gtggtcgcta ctaaaggcga tctgctggac caggagcgga aactcaacaa gtccggcctg
     2041 gctcactatt tccatcatat cgaaattatg agcgataaac aggaaaaaga ctaccgtaaa
     2101 ctgctgcggc atctggattg ctcaccggaa gcatttctca tgatcggcaa ctccatcaaa
     2161 tcggatatat tgccggtact ggcgattggc ggccacgcta ttcatattcc ttatcatacc
     2221 gtatgggcgc atgaagtggt ggaaggagag gtgaaagacg aaagatttta ttcatttgaa
     2281 aacatttcgg cgatcctgcc gaggctattg tcatgaaaca gctgctggac attaatacct
     2341 gggccagaaa agaccattat cattttttta gccagttcga ggagcctttt ttcggcgtat
     2401 gcgtaaatgt ggattgtacc cgggcttact acgtatccaa ggcgcgtgga tattcctttt
     2461 tcttatacta cctgcataag gccatggtag cgatgaacct tacggaacct tttcgttacc
     2521 gtatcatcga caaacaggta tgggtatacg accatattga tccttctccg accatcaacc
     2581 ggccggacgg cacttttggt tttgcttact tcccttacca tgcggatttt gaaaccttcg
     2641 cagcgacagc gcgcgtggaa acagagaagg tgcaaagcag cagcggtctt atacccgccg
     2701 tatccggtga aaacgtagtg cattgttctt ccatgccctg gatcaatttt accgggttgt
     2761 cccatgcccg cagctttact ttcccggaca gctgcccgaa gatctccttc ggtaagatga
     2821 ccgataacga cggtaaaatg acgatgccgg tatcgctaca tgtgcatcat gcgctgatgg
     2881 atggctatca tgtggggctg ttcctggagg agttccagcg acagctggat gtatagttac
     2941 gccaggtagt tgctcacttc aatcaggttc ccgtccgggt cccggaagta aatggagata
     3001 accaaaatat cacacattga caattcaata cgcatatcag aatttacgca ataaacagcg
     3061 gttaatgttt gccgtctcca tctgtacgtt ggggatgatc gtcgcgaatg tgttgttgga
     3121 ctattggtat tcctggtacc tggagcgtgc cttttacatg tcggaatcgc tgttgttcag
     3181 cgtctactgg gtgatgtttt tgcctttgtt gccggcgttg tggtggctga tagaaagaac
     3241 ggaaaaggtg ggattgaaat ttgcctttac aggcggcgcc attgcttttc acctgttggc
     3301 ctacccggca ctggtgtggg tactgtcaaa aatgttctac taccacactt tttcctttgg
     3361 gcagactttt caattcggac tgtctgctta tttcctgaaa tcggtcattg tctatgggtt
     3421 tttgctgttg atgttaacga tactacgtaa aaaagtggtt tccccgccaa ctgtccggga
     3481 ggcagccagc agcacaagtt accttcatgc gcttatcgtg gcggaccatc atcatcagaa
     3541 acaggtactg gcggtcaacg atattttttg ttttacggcc tgttcccctt atgtaaccat
     3601 ccatcattta tccggtaact acctgtatgc ggaaacactg aagtccctgg aaagccggtt
     3661 ggatgaaata cagtttgtga gaatacataa atctcatatt gttaaccttc agaagataac
     3721 ttcctatcaa tcccggcaaa acggagatta tgatgtcttc ctttccgatg gtgctgtggt
     3781 aagggcaagc cgcaattatg cgaaggcctt taaatcaaag ttggaaagat ggactcagca
     3841 tacggtaaaa taaactcagc ttaccatatt aggtttgaaa atcagaggtt tgtctggtaa
     3901 tctttgtgaa aaagttcaaa gatggaaaga tccttttttt gcaaagttac tttgattggc
     3961 tgcgcgctct tcatgagttg caatgggcag acaaatgacc ggccggtaca aaaaatcgtc
     4021 ggtgggggct gtgatggttg tgaattgatg tatatcggca tgccccaaaa aataaatgct
     4081 gttgatacaa gccccggttg gaatgaagaa gggcagcagc tgatggtgac cgggacggtc
     4141 tttcagcagg acggaagaac gccggcaaaa gatgtcgtta tctactattg gcataccgac
     4201 aatgatggat attattctcc cgctccggga atggatgaac gggtgaaacg ccacgggcat
     4261 atccgcggat gggtaaaaac cggcccggat ggaaaatacg ctatcaaaac gatccggcca
     4321 gccccttacc cgaaggatat gttgccagcg catattcatt tatctgtcaa agagcctgct
     4381 gttgctaatg agtattacac cgatgaaatt aatttcgaag gggatacgtt gctggtagct
     4441 catttcagga aatatcctcc tgaaaaccgc ggtggcagtg gcgtcgtaaa ggtgcagctg
     4501 aaagacggcc ggcaggtagc agaacataat attgttctcg gtctgaatat tccgtattat
     4561 cctaaaaagt agatggctgg gatttcagga cgataatagc aatcgcttca ccgttcagga
     4621 taacgaaaga taaccggggc cgttgagaga ggggcgtacc cggtgttgga aacacgcttc
     4681 agggttggcc caacaacaaa tttttcaccg gactataata atttcaatcg attgcgtaat
     4741 ttaagcctta ttcccttccg ttatgaaaaa catattcatc ctgttactgg tcatcttact
     4801 tgcaggaacg gcgaaagcgt tgcccgccgg gctgccggta aaaattccgg cttccgccat
     4861 gagggccatt cccttaccgc tgccgcgtgc gcaggccggg ccggcatccc cgcatatcgc
     4921 ctccatcgtt gcagacacga tcaaagtagt cacaggcagc actgttgcct atacggtaga
     4981 taccaaagca gatgaaggcc tggtcagtac agccaccacg gtagcgcacc tgttggccga
     5041 actgcaaacc aatgtagcgg tgcagcgccg ccaggtgacg actgcagacg gcaaccccaa
     5101 agatacgggc gttatccagg caggggatcg tcttatcctc actaatccaa ggggtagcac
     5161 catctactac ctgctcccgg agcaacgcgc cctcacgggg aaactggagc tgttgcgacc
     5221 ggtggtcacg gcacaggtga aaaataccat tacgcttcac tacaccgccg gccagcggag
     5281 cccggatgct actgtaacga tacatttccc ggcaggcatc acgatcaccc cggaaaatac
     5341 aacggtcaac gtgatcggcc gcggcgccgt gctgctcagg gacctgcccg gccagtccat
     5401 cggccgcaca ggtacccgct actcctataa gcgtgtgggc gaagccgtta ttgaaaaggc
     5461 cgcagatgga agcaccacgc ttaccttgcg tcacctggac ctgcgcccgg ccaatgggcc
     5521 cgacctggtg ctggtgatac aggatgttat gctgaacgac agcggaagat attttataaa
     5581 cgctaccagc accacctcgc agccggcggt gctggccagc tcggggctgg caggggaaac
     5641 tgcggacctc tgggtgacca acaccattgc agattttaaa agggtagtgg taaaagataa
     5701 accgtatcat gaattacccc atgactatac gcaggtgcag ttccgctgga cgccggtcac
     5761 cgccggcaag gtgactatgg aatactctac agacaccggc aggcactggt cagccgccaa
     5821 agcgagcata gacgcagcgc atggcacggc gttcatcacc ggtctgcgcc gtgacaagct
     5881 atatcatttc cggctgctgg tgaaagacgg cgtccatcgc ggcagctcca acatcgccgg
     5941 tgattatacc ggcatgctcg atgtacggat gtttggcgta cacggtaatg acaccgccga
     6001 tcataccgcc ggtatcaatg aagcgatccg ttttatgcac aacatcggcg gcggcacttt
     6061 attattcagc gaaggcgtct acaacgtacg caccgtacac ctgctaagca acgtatacct
     6121 atatatcagc aaagaggccg ttatccgtgc ggggaaaggt gccgacgccc cggaaaccac
     6181 ctggttcagc gacagggcct atcgctccgg cctttcacca acagatcgcg gtccttacga
     6241 agacccggaa aactacctca ccaagcagga cgtagggcat cactacttcc acaacgccat
     6301 gttcttcgga gaacggctcg ataacattaa aattatcggc aacggacgca ttacgggcaa
     6361 cggccacctc gttaccagtg acaaggtgat gaacaacgct cccgacaaac gggcagataa
     6421 gatgttttcg ctgaaactat gcaccaacgt ggaaatcggt ggtctccacc gggaccatga
     6481 cctctggtat gattccgtga aagacgtccc ttattatgtg gataaaggtg gtctgccctc
     6541 gtatgatgac agcaacatgt tgcagataga tcgtgcaggt cattttgtgc tgctggccac
     6601 gggcacggat acactttttg tacatgacac ttactttggc aaaatggacc aggccaacgt
     6661 gcgggatatt tatgatttta tggcgtgtaa ccaggtaacg gtgcggaata tttattcccg
     6721 cgtcagttca gacgatatcg tgaaaccggg atctgactgc tcactgggat ttacccgtcc
     6781 ggcgcggcat taccgggtgc gcaacgtgat cggggatacc aactgtaacc ttttccagat
     6841 aggctccgaa acggcggacg acatcatgga catctgtgtg gacaacattt atgtcctggg
     6901 cgccaataag gctgggtttt ctatttccac caacgacggc ggacgggtga aagatattca
     6961 tctcaactgc ggacataccg gtccggtgaa ccagcggtcc cgcatgatgc gcaccacggc
     7021 gcctttcttt atctccattt ccaacagggg ccgcgtgctg ggggcaacgg tggggcaata
     7081 tactttcgtg gaagagggcc ggaagcggac ggagttgctg gtgcaaaatg tgaatatcgg
     7141 acaggtggaa aacatcgtga tcaacagcat tgatatttca gaagtttacg ggggcagctc
     7201 ttttggtaat ggtagccgct ggaagccatt cgacggatcg cagcaccgcg ccacttccat
     7261 catcgccggt tatgcgctgc ccgcggcggg ggcggtggaa ggcggactgg attttacgct
     7321 gccggatggc cgtcataccg gctatatccg caatgtggtg tttaacgatg tgcatatcac
     7381 ggacaaaggc gggcatcccc tggccgatac ggcgcagcgg ccgccggaac tgggagtagg
     7441 gcagtataat gtgtctaacc tcaaagtaca gccttcgtac ggactatggg cccgtcatgt
     7501 ggaagggctt accatttcgg aaagttcgtt cagatttgag cagcccgaca gccgttacgc
     7561 tttgttcctg gatgatgtgc agggcgccgc gctctttggc attaaaaccg tcagggccgc
     7621 cggtgacagc gaatggctcc gttacatccg gtcttccggc gttcgttgga agaatatcct
     7681 gttttaccag gaagcgtggg gcaaatcgcc ggtatcggcc ggcagccgtt aggatggcta
     7741 ttgggcccgg gtagccatgg taatcgaaaa ctccagtttt tgggcattga tttctttcag
     7801 cggaatttcc ttttcattat caaggccacg ggtgaaatat accgtggttt ttagcgtttg
     7861 ccccttgtcc agcccatctt cgaaaagggc tacgccatat agttctttgt ccccggtaga
     7921 tgttgctgaa atacgcagaa cgccgatatt gtactggccg ttgttcttca ccgtgatgat
     7981 accgttctgg taggtgtaag tgatcccttt gatggtggcc aggtatgttt tgttggtact
     8041 tgtcggggcc ttgtacgtct ggcattttgc catgaacgga gaaagtgcta aaaacagcga
     8101 aaaaatcagt aatttattca tcgaaagata aaaatatatt gcaaaaatac attttatctt
     8161 tatacggcga attgtggtta atttcgtaac agtattaatc aaggatgtga tgtttaccgt
     8221 ggagaatgtt ctcagcaaac caatatccca atgacctatt tcagactatt ccaccccgtg
     8281 ctgctcgcgc gggagatcat acatacgggg actgcccagc tggaaggaga ggagaagaaa
     8341 cgagtcagta tcatcaacac cctcagtctt gcatctattg cgctttgttt gattttcggt
     8401 accgttatct actatcttac cggtaatctg gagatcctgc tacccgctta cgcagaagcc
     8461 cttttgtttg tggtggtgct tatgctcaac catttccgtt ggcataatac ggcagccatc
     8521 ctgaccgcct ttgtgcataa tctttccatc gtttacttca gcgccttgct gggcatggta
     8581 acggaagtgt acctgctttt ctttttcctt ttaggtgctg cgctgatggt atttcatggc
     8641 aagcctttgc tgataaagtt cagtattgct atctcggtga tctgcctggt attgtgtgag
     8701 ctgaattact attattattt tatagaaccg ctggagctct cgcattacga acagttcctc
     8761 attcgctggg tgaccatccc ggccatcctg gtgctggacg tgcttacttt tgccttgtat
     8821 gtacgtacgc tgcgccgtaa aaacgcccag ctggagcgga aagctaccgc gctggaaatg
     8881 gcggacaaag ccacccggcg gcaggcgatg gaaacgtccc atgaaatgag aaatccgttt
     8941 aacgcggtgt atggcatttc acaggacctg ctgatgcagg tacagaaaag tgacctgtat
     9001 cccgcggaac tgaaagcgtc tatagagcat ttgtattccg cctcgcataa tgtgttgcag
     9061 atcctgaaca acaacctgga gcatttccgc cagcaggaag gcgtggcgcc gcagctggag
     9121 tcaggcgcat ttaatgtgcg ggactgggcc ggcgaggcga cggccatcta ccagtatatc
     9181 gcgaatgtaa gagatgtcag tattgctttg gagatagacc cgaagatgcc tgcgcggctg
     9241 gagggagata agatcaaact gacccagata ctcaataacc tgttgttcaa tgctatcaaa
     9301 ttcacccatg cgaacagcac cgtaactgtg cagatcaggc ctgatggccg gcaatggcag
     9361 ttgctggtaa aagacagcgg agacggtatt ccgccggagc gtctgtccac tattttttcg
     9421 ccctatgtgt ccgaacaaca tgctttcgga gggactgggc tggggctgcc tattgtgcag
     9481 cgtttcgtgg aactgatggg cggtactatc gctgtgacca gcaaaaccgg agaaggctct
     9541 gtgtttacgg tcaacctacc gctgacagcc gtagaggagg cgccggcccc ggaggctcct
     9601 gcgaataaga acatcacgct gcaggctttc cctggtgtga aagcgctggt ggtagatgat
     9661 aaccagatga gcaatatgat cctgtgccgt ttcctcgaac ggatggagtg cagtacttcc
     9721 gctgctttgg gcggagaaga ggggctggag aaagccattg ccacgcaacc ggacattatt
     9781 ttcctggact cccatatgcc gggtatggac ggtaaagcca cgctggcagc gttacaggac
     9841 aatcctgcaa cgcataatgc catcgtgatt attgtttccg gcgacgcggc cgaggcatcc
     9901 attgcagaga tgctcgcagc cggcgccgat gattttatga ccaaacccat tgatctgaaa
     9961 agcctcaacg agttaatgat cagatttgaa gctcgtctta ctacaaattc tcagcgtaat
    10021 ccgtgattcg caggtcctgg ttggcgatac cgtagcggct ggtatctttt gtgctccagg
    10081 aaatatttcc ttccatcata tgttccagca taaggatata gctgtccagc agcggataat
    10141 cctgtcctga gctgagtgac agcagtattt cagcggtatg caggaactgc ctgatttcat
    10201 cgtcgtgaac agcggcagct tcgtggacgg ctttttcgag gggcagctgt cttttgtttt
    10261 tgatcatcat gacaaggttc agctcgtcgc cctgttccag ctccttggta taggaaaaca
    10321 ggtcgttggc ccagcagatg gtccggctgc aaagcaggcc gaggtctttg atcagcgggt
    10381 cggcatacca ggatgccggc agatgaatgc cttccatgat ttctgcgagg tcgaggaaga
    10441 agttggcgcc gccgatcccc gggcggtgca gcatataatc ttccagcgag atgctgccga
    10501 tagcagtcac atgttgcatg cgccagctgt tggacataaa agccgcctgg aggctggtgg
    10561 tgaaccgctg ctgccagtcg gccggcccta tctgtaccat acgccgccag atgtcctgca
    10621 tggcgagcag caggggaggg tcttgcagcg gctccgcctg gtacctgcct ctcagaatac
    10681 cgatcatttt accggcgagg gcttcaaagc tggtgccggg atcgttgagg gtgatacggt
    10741 ctatctcatc gtcccaaagg aacaggaggg tgttgaagtc cgcagcgatg gcgaggcgga
    10801 agagatcggc gttggggaac atgcgggcca ccatccaggt gaatttctgt tcctggtaca
    10861 gctgccattg accgtcgttg ttgtccagcc cgaatttccg gacccaggcg gccgtatggc
    10921 ggtctgcttt ttccaccaaa ggattgagtt ttcccgggaa ggggcagtac agccccggaa
    10981 gtgttgttgt ttccataaac taatatttaa gtgtttaaaa agcgtaggcg ggcgttcttc
    11041 gggtgctttg atcacctgta ccagtagtat agtcttcacg gatccatctg ctcggtcgtt
    11101 ggctgttgaa taaggccggg atagctggca gggcaaaaca ggacgcacct aaaattaaga
    11161 ttgtggcgtt aattagccgc gccatttccg cagtttaaca ggcgcagggg aacaatacgg
    11221 ggagaaatgc gcccgttgga ggggtgaaat gccggtattt gactggcgta ggttgcccgt
    11281 tttaataatt ttttcgtttt gagatagtac ttatttgaag ggagggcgtt actaattcag
    11341 tagtctgatt gtattgttca tgctgttgtc atcaacagcc atcattttat tcatagtaaa
    11401 catgcgtttc agaattaaac taaaagccac gcaaccggca gccgtcattc ccattaacta
    11461 tccgtatgcc ttatcggcag taatttccag aatattacac caggctgatg aagactatgc
    11521 gtctttcctg catgagaaag gttgtgcaaa ggctggttct cttaaagtat ttaaacactt
    11581 ttctttttca gagatccgaa ctgcctttcg gatagaagga gaccgtttcc gttttctttc
    11641 cgacgaggcc atgtttatga tctcattcca tctgccacag gctgcggaaa gctttattca
    11701 ggggctgttt ctgggagaga ccatagaaat tgccgatcgc cgcagccagg cggccttcac
    11761 gatcactgag gtgctcccga caccgacacc gctggaagat attccggata cagccatcac
    11821 ggaagtgata ctgcaaccgt tttcaccgct ggtttgcggc actaagaatg acaggggata
    11881 ctatgatttc ctctcgcccc agcatccgga ttttgtaaaa caactggtac atacctggcg
    11941 ggagaaattt atcaccatgt atggtgaaga agaagtggat accatattcg atcccgtgag
    12001 cgtggaagtg gtgatgatgg aaagaccgcc caaatcacgg ctggtgacca tcaaagcgga
    12061 tacgccgcag gaaacgaaaa tccgcggcta cacgaatttc aggctgaaag taaaaggcgt
    12121 gggacaggca ctgaaattac tggccgatgc cggcgccggt gtatacaaca gcgccggaat
    12181 gggaagctta cacattttat aaagatattt tttgcgtgcc catggtttca atggtcgctt
    12241 gttgagtcga tttatctaaa gtaaagtacc attgtgaatc gttcacttct ccgcaataga
    12301 agtggaatag tgtttacgac atcgtcgatc accggagggg gatcgacgat ttttttgaga
    12361 aggccgtggt tgtcaaaaaa aattactatc tccgcatttt cccgtgaagt atataagttg
    12421 acaattgtaa ataatattac aataattcaa gggttggtta gtttggaggt gaaaagtgat
    12481 catatttata tgcatttggt agaaagtgct cccttcaata aaggaaagat gaaagtttat
    12541 gccggtgttc ctggtaatct tgtcgcattt gtgtgtcggg tctctttcag aagagggttt
    12601 gatggtacag tttcctttct ttcaaagaca caattaattg atcattatat tgaaagtttg
    12661 ggcgctattc acattggcgg gcaacgtatg attatcgaaa cgaaagccgc actaaaattg
    12721 attgataaat actttaaaaa ctaggtaaat gaaacatcgt aaggtagaat tggacgttga
    12781 ttgtattggt ggggtgaggc ctttaaccaa ggaagatgaa aaagtaatca gtgagtttat
    12841 caaggaaagg aaagacgcta aaggaaaaac cggatcagct gcgatagctg gtagagatcg
    12901 taaaaccgtt agagtaaaga ctaagtcata gttgctttct ttcgtgataa atagctcgct
    12961 aggaccactt tttatttctt aggctgatga tttgaaattt aatctcattt aaccaataac
    13021 attaaaaaga cctgcatctc tgcaggtcct gtttataaaa aataatttct tacaacccct
    13081 cgtccaccag atacagcacc gattcgtaat ttttcttcac cgctgcagac atcgcaattt
    13141 cacaggtttt ggtagaagaa taatagccgt catgctcgtt acattttacc tccagcgact
    13201 caggacgtgt agccgatgcc gttagttccg ggaataagaa cccgcgatca ccggccatgc
    13261 cgcagcaacc ggcatatttg ggaactacca cctcttctgc aaagaactgt gccaccttta
    13321 cgaacttagg ccctgtcttc attttctcca gggagcacac ggggtgcagc gcaatacttt
    13381 ttttcttgtt gatggctgtg accttcggca gtacgaagtc gtgcaggaaa tccacggcgt
    13441 cgaggatacg gagctggtcg aacttttctt tgttggcggc gttgagcgca gggcgcacat
    13501 gatgcagcgt ataggcgcag gaactcacgt cgatgactac cggcagcgca ccctggcgac
    13561 tgtcatgcca cagcttttct ataatgtggt tggccgtatg ttcgtaggcg tctttatacc
    13621 ccttggaaga aaagatctgg ctgcaacagg tgccgctgag attatcggga acgactacac
    13681 tgataccggt tttccggcag acgctcatga atgtctccat caggtttttg gatttgcctt
    13741 cgtaagtgcc gagcatacgg gagatacagg ccgggaagta gacgatggaa gcatcggcag
    13801 actgctgcgg tttaagaata ccaaggcctg gcgccggctg cagctgttca gaccataagg
    13861 gtacagcagg aatgatgctg cggatacctt tggtgatact ggtcatggca tgtttgccaa
    13921 acacccggtt gatgccggta cccacctgga tcgcagtcct ggcggcccat tccaccgtcc
    13981 tgaaatgtct ggctacctgt agggcgagtt tattggccgt aggggagtgg ttttcgcggc
    14041 ggagccgctt caccagatcg ccggtgttga tgtccacagg gcaggcggtg gcacagagac
    14101 cgtcaacagc gcaggtttcc agcacatcgt actggtattg gtcgaggagc actttgtagt
    14161 gggctttgtc gccgtttttt tgcagttgtt tgagcgctcg ccggatcacg atccttcggc
    14221 ggggtgtggt ggtgatatcg cggctcgggc atttatgttc gcagtaaccg cattcgatac
    14281 agcggtccac ctcctcttct acggtaggca gttccttcag gtgtttgagg tgggcgcggg
    14341 cgtcggggtt gatgatgacg ccgggattga gcaggttatg cgggtcggcg gcctccttga
    14401 ccttcttcat aatgtcgtag gcatcgccac cccattctgt ttccacgaaa ggcgccatgt
    14461 tgcggccggt gccatgttcg gctttgagcg tgccatcgta tttgttgaca acgagagcca
    14521 ccacgtcctg catgaaaagt tcgtagcggg tcacctcatc aggtgtatta aacgattggg
    14581 tgaccacaaa gtggatatta ccgtctttcg catgaccgaa aataatagca ttgagataat
    14641 gatactgtgc gaagagttgt tgcaggtcga gaatagcgtc accgagttta tctaccggga
    14701 aggcaatgtc ttccaggata acggtggtgc cgctggcacg aacggcgccc acagcgggga
    14761 acagcccttt acggattttc cagaagaagg attgttccgc cggatcgatg gtgaacaccg
    14821 gtggttcgga catatcgagg ctggcggcgg aggccatgaa gccgttgaca cgggcgtcga
    14881 gggcagcctg actttcttcc tggaattcta tcagcagcgc ggcggctgtt tccggcaacg
    14941 tcttcacaat agatggcatg ccgtccatgt cttccacggc atgcagcgag gcgcggtcca
    15001 tcagttccac catcagagcg cctgcgttgg tcagcggcac gatggcctga cacgcggcat
    15061 agatggtcgg aaaatacagc agcgcggtag atttgtaggc atagtccggc acggtgtcca
    15121 tcaccgcttc ggcgatgaac gccagcgtgc cttcggcgcc tatcaacagg tgggccatga
    15181 tgtccagcgg atgatgataa tcgatgaaag cattcagggc gtagcctacg gtatttttag
    15241 tctggtattt atggcggatg cgatcgtgta aagcgcgatt agcggcgatc aggtcgcggc
    15301 agtcggcaag gctcacaaac agcggcgcac attccatttc aaaacgggcg taatcttttt
    15361 tatgctccgt gctgaaagta ttgccgtcgg gcaggataaa ccggatgtgc cgggtggtat
    15421 gataggagtt gagcgctacg ccgcaacaca tgccgctgga gttgttggac aggatgccgc
    15481 ccatcatggc ggagttgatg ctggacggat caggaccgat tttacgggcg tgctttttca
    15541 ggtacgtgtt caccattgcg ccggtgatgc cgggctgcac ccgcacggcc tgcccttttt
    15601 cttctatctg tatcttattc cagtactggc tcaggtctac caggatacca tcggtaatgg
    15661 actggccgga aaggctggtg cctcccgtac ggaataccag cggaatacgg aactgctgcg
    15721 agaaacggaa caaagcaacg atctccgctt caccgatcgg ttgcacaact gcctgtggta
    15781 ccaggtggta gaagcccgcg tctgaggcat atgagataag atctatatac ctggacttga
    15841 tacgattttc aggtaagatt ttcttgagtt cgtgtgcaat gttcatggcg actgtcctta
    15901 ttccttgact ggttgaagtt cacattatgg atagcaagtt atataatttt acatcttttt
    15961 atatctttag ccaccgcttt cttaaataac ccgtatttca accatgctca gatgtaacaa
    16021 cctattgccc gttttgctgt tggctgatct cttcctgata acaccgttac tgacccatgc
    16081 gcaacagcct gcgggcgata ccctgccggc accgaaagta cgccagctgt cagagatctc
    16141 cattatacaa caaaaggcat tggtggaaag aaggacagac cggctgatct ataacgttac
    16201 cagcagcgtt ggggccgccg gcgccaacgg actggaggtg atggcccggg tgccgggctt
    16261 acgggtgacg gacaacctga tcgctatcgc cggcaaaggg gctgtaaagg taatggtcaa
    16321 cggaaggatc atcccgctgg cgggagaaga cctgcagcga tacctgaagt ctatgtcagc
    16381 aggggaaatc gcccgcgtgg aggtgatcac caatccatcc gctgcttatg atgctgacgg
    16441 taatgccggt ctgatcaata tcgtgacacg gcgtgacaga aatcagggct tcagcgggga
    16501 gatacaggcc agtggcaaac tgtcggacta cggtttcaaa aagctgtacg gcgtttccaa
    16561 ctacggtacc atgtccgccg gcggtaactt cagctataat acccgcaggt ggtcactgta
    16621 tggtaacctg aactatgaac acggtcgctt tcttgaaggt ttcggcattg acctgcaata
    16681 tccgaaccgg ttctggtctc agacagacac cggcaactat aagatccgca acctcaacct
    16741 ggtactgggc acagactaca agataagtaa ccgcagcacc atcgggttta attacagtgg
    16801 cgcccgcacc gcttatattg gcgacgatca tgtgaacaac ccggtattta ataccggcgg
    16861 cctattggat tcactgctgc gtactttcgc tacttatcag ccggtagcat ggagcacggg
    16921 actaaacctg cacctggtga caaagctgga ctccagcgga agacagtttt ccgtagatgc
    16981 ggactatttt aattattacc gtaccgataa atcagatttc atcagccagc gctatgacag
    17041 aaagggagag gctatcgcca acggtaccac caaatatttt gataccaaca aacaggcgat
    17101 caatatctat accctgaaag cggatttaca gtggcctacc acctttgcca attacgcctt
    17161 cggcggaaag ctgagcttta tcaataacta cagcaacgta ttttacttca ggaacctgca
    17221 gggtgaaatg gagtacgata aaaaccttag taacgaatac gactatacgg aaaataccca
    17281 ggcagtatat gctaccgcgt ccaaagaggc cggtaggtgg aaactcaatg ccggcctgcg
    17341 tatggaagcc acccagacaa aaggggtgtc tcatgtgcag gacaacgcaa tgggcaacaa
    17401 ctatgtgaaa ttgttcccgt cgttctctgc tgactggaac tatcataacg acaatcacct
    17461 ggcttttacc ttcgggaaac gtatcaacag gccggtgttc tgggacctga acccttacaa
    17521 gtcgctgact acggcctaca gctacctcga aggcaatcct tacctgcagc cggaatataa
    17581 cagcaacttc gagttgtcgc accactggca gcaccgcttt acagccgctg ctttcctgaa
    17641 tatcaccaat aatggcttca atcgtattac cgtagcaaca cccaataata acactgttta
    17701 taccacgccg gagaacttcc tgaagatata ccgctacgga ctgtctgcca gcgccacgct
    17761 acagccgcta ccctggctgg agagcgttaa ccagttgagc ggttatcata ccgatgcccg
    17821 cagcgccctg cccaatattc ctgatatcaa cggcatgagc gtatacctgg ctaccaacaa
    17881 taatatcacg ttgaaccaag acaaaaccct gatggcggta ctcaactttt ggtgccagtt
    17941 tcccgaagtg gaccataacg ggaagtccaa tacctattat aatatggacc tcggccttaa
    18001 agcggtctgc ctgcaaaacc gcatgagcat tgcgctcaac ggcgcggacc tgttccgctc
    18061 cagcgccagc atcgtacggt ccacggtgaa taatattccg cagacgttca cccatttcca
    18121 ggtgaacagg cagatacgtc tttctgtgag ttacaagctg ggacaatcta cccgtaagcg
    18181 ggaggtgagg ggtacgggta gtgaggagga acgtaaaagg acttagttgt aacgttactg
    18241 gaaacgtgcc gggccacctg gctctaaggc gcaggcgccg ggctgaaaaa tgcgattaat
    18301 tcttttgcaa ttttctccgg gctgttgtcg ttatcagcgc cggtggtata ctactctaag
    18361 aaggttattg ctgcgctgtg tttatcatct aaaatacgac aaagttatgt ccttccctaa
    18421 tgctcattat ctctgacttt ggtgctggag cgcatccgga tctttatcca tggcctgttt
    18481 tcgataaaat tgaacagttg tttaaaaaag ttgttcaatt tcaaaatatt gttttacctt
    18541 cggtttaaaa tcaggcatat ggcagtaaaa aaggaacagg acgccagcac agaagaaagg
    18601 atactggcag cagcgcggat cgtatttacc cgtaaaggat ttgcggccac caaggtacgt
    18661 gatattgctg ccgaggcaga cataaacctg tcactggtca actattactt ccgcagcaag
    18721 gaaaaactgt ttgaagttgt aatggcggaa gcggtacaga agctggtgtt tgagattgcc
    18781 accattttta acgatacgca actgggtatc ccggagaaga tcaccagggc ggtcaactat
    18841 tatatagacc tgctgctgga gaacccggat ttcccgctgt ttctggtcaa tgagattatt
    18901 accggggatg atatgtttac ccgttttgcg caacagaaca ctttgttcca gtcggacctg
    18961 atccggcagt tatttgccat gaaggaagaa ggtaaactgt ccgttcatcc ggtgcatgtc
    19021 atgatgaacg tgatagggct ggtggtgatg ccatttctgg ccaggccgat actggagcgg
    19081 aatgcactgg tgaaggacgg ggagtttgtg aagctgatga atgagcgaag gacactgatc
    19141 ccgttgtggc tgaaaggtat gctggggtag taacggaagg tgggagctgg tgagtaggca
    19201 ctccctccgg gttgatggct gaaaggtatg ccgggggtaa taaccccttt ttttgaggtt
    19261 ggattgaaca attttttaaa acaatatttc aaaccgaatc atgcatcatg aaagtatgta
    19321 aactactggg ttgtatcatg atgttggccg ggcttacagc ggaggcgcag cagcaagcgc
    19381 tgaccctgga aacctgttac gccctcgcca gacagaatta tccgttgatc aaacagtacg
    19441 atctgatagc gcgcaccagc cgctacaccg tggccaacgc cggcaagctg tatctgccac
    19501 agctgacggt atccgggcag gctacttatc agtcggaggt cgtcaacttc gctgaagtgc
    19561 tgccgcccat tcccggcctg aacccgccac agctcagtaa agaccagtac cgcctgcagg
    19621 cggaggtatc ccaacaaatc tacgatggcg gcgtcacgcg ctaccagcag gaagccagcc
    19681 gcgccaacga aaaagtgcag cagcaaagcc tggaagtgag cctctatgct gtccgcgaaa
    19741 gggtgaccca gttgtatttc gctgtactgc tcatggatgc tcagctccgg cagaacgccc
    19801 ttcggcgcga caacctgcag agcactactg ataaaatgaa agctgccctg gctaacggtg
    19861 tcgcctatag gagcaacgtg gcagagctgc aggccgaaat cgtgaatgct gacatggcca
    19921 ccacggaatt ccgtgctaac cgtaaagcct atctgaaaat gttggccacc ttcattcatc
    19981 agccgctgag cgacagtacc gtactggctt atccggaaac gacacgcccc gccgaaggga
    20041 ttcatcgccc ggaactggcg ctgtacgact atcagcagaa tacctacgat gtgcaggaac
    20101 ggcagctgaa agccgcttat ctccctaaac tgaatgcttt cctgcaaggc ggctacggac
    20161 ggcctaccct taatatcgtc agcaatgaat ttggcagctg gtggatggga ggactgcggc
    20221 tcaactggtc catcggcagc ctatactccc tgaaaaacaa ccgccgcctg ctggacatcc
    20281 agcgcagcaa tgtggacgta agccaggagg ccttcctgct gaacacaacc ctcaccatgc
    20341 agcagcagca tcaggatgtg gataaatatg cagccctgat gacacaggat gaagaggcta
    20401 tccgcctgcg ggcagccgtg ttgcaatctg ctaaagcgca actggacaac ggcgttatta
    20461 ccgttcatga atatatctcg caggtgaacg cggaaaatct ggccaaacag acgcgtatcc
    20521 tgcatgaaat acagctgcta caggcgcaat acaattataa aaacacttcc gggaactgat
    20581 taatttcttg taacatgaaa taccatctca tttggatgac agccgccgtg atgatgacaa
    20641 gtgcctgcgg ggacggcaaa ccgggctacg acgcctccgg caactttgaa gccgatgaag
    20701 tgatcgtgtc cgcacaacag aacggcgaac tgttatcctt ccccataaac gaaggggaca
    20761 aactcaatgt tggccaggta gtgggccaga tcgatgtgac cattccggcg ctgcaacagc
    20821 aacaggtgca ggcctccata catgccctcc gggagaaaac caacaatccg cagccacagg
    20881 cccagctggt ggaacggcaa ctggtggtgc aggaagcgca gctgcaacag ctgtaccgcg
    20941 aacgcaaaag aacggagaac ctcgtgaaaa gcgacgctgc cacccagaaa cagctg
//
