LOCUS       NZ_FTMW01000003        23014 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain RU36A, whole genome shotgun sequence.
ACCESSION   NZ_FTMW01000003
VERSION     NZ_FTMW01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900156365.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:00:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,232
            CDSs (total)                      :: 4,119
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 113
            rRNAs                             :: 9, 7, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 1 (5S, 16S)
            partial rRNAs                     :: 6, 10 (16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 89 of 145
            Pseudo Genes (incomplete)         :: 67 of 145
            Pseudo Genes (internal stop)      :: 30 of 145
            Pseudo Genes (multiple problems)  :: 33 of 145
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:06:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 23014
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FTMW01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..3014)
                     /gene="ppsA"
                     /locus_tag="BW968_RS10180"
                     /old_locus_tag="SAMN05878487_2037"
                     /pseudo=""
     region          1..23014
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..23014
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23014
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:3014](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..3014)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             complement(<1..3014)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     1.4e-91. Score: 298.9. Matches aSDomain:
                     nrpspksdomains_BW968_RS10180_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-864). E-value:
                     5.7e-113. Score: 369.5. Matches aSDomain:
                     nrpspksdomains_BW968_RS10180_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (966-1003). E-value: 4.6e-13. Score:
                     41.2. Matches aSDomain: nrpspksdomains_BW968_RS10180_PCP.1"
                     /codon_start=1
                     /gene="ppsA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="BW968_RS10180"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2037"
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsA"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 4e-76, bitscore:
                     251.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-121, bitscore:
                     401.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTL
                     EGALNHSISRNDAIRFQLLEGEELEPRLLLTEYKYYPLRIIDFSNVEMIEIEQWIQDQA
                     SIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDP
                     LPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSAS
                     RDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKD
                     LHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQN
                     TLFSLEDIKRIQSHLLTILENALQHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAF
                     TLHGLFEQQAASTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSER
                     SPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLE
                     VDMTSLEREEVKRYVSASVSDGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFP
                     LSEDDIVMVKTSFSFDASVWQLFWWTLSGASAYLLPPGWEKDPALIVQAIHQENVTTAH
                     FIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTE
                     ATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVAR
                     GYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRTDDQVKIRGYRIEPR
                     EIEAALRNIEGVREAAVTVRTDSGEPELCAYVEGLQRNEIRAQLERLLPGYMVPAYMIE
                     MEQWPVTPSGKLDRNALPAPSGAADAETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNF
                     FDRGGHSLKATALVS"
     aSDomain        complement(6..116)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BW968_RS10180_PCP.1"
                     /evalue="4.60E-13"
                     /label="BW968_RS10180_PCP.1"
                     /locus_tag="BW968_RS10180"
                     /protein_end="1003"
                     /protein_start="966"
                     /score="41.2"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALV"
     aSModule        complement(6..3005)
                     /complete
                     /domains="nrpspksdomains_BW968_RS10180_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_BW968_RS10180_AMP-binding.1"
                     /domains="nrpspksdomains_BW968_RS10180_PCP.1"
                     /locus_tags="BW968_RS10180"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(393..458)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0008"
                     /evalue="6.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="BW968_RS10180"
                     /protein_end="874"
                     /protein_start="852"
                     /score="37.3"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPREIE"
     aSDomain        complement(423..1625)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BW968_RS10180_AMP-binding.1"
                     /evalue="5.70E-113"
                     /label="BW968_RS10180_AMP-binding.1"
                     /locus_tag="BW968_RS10180"
                     /protein_end="864"
                     /protein_start="463"
                     /score="369.5"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FEQQAASTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNE
                     SIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSA
                     PNFSGETLEVDMTSLEREEVKRYVSASVSDGSLAYVIYTSGSTGQPKGVAVEHRQAVSF
                     LTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWTLSGASAYLLPPGWEKDPALIVQAI
                     HQENVTTAHFIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRTDDQVK
                     IR"
     CDS_motif       complement(540..629)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0007"
                     /evalue="6.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="BW968_RS10180"
                     /protein_end="825"
                     /protein_start="795"
                     /score="56.9"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       complement(1155..1214)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0006"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="BW968_RS10180"
                     /protein_end="620"
                     /protein_start="600"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       complement(1398..1439)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0005"
                     /evalue="6.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="BW968_RS10180"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.2"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       complement(1962..2075)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0004"
                     /evalue="5.00E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="BW968_RS10180"
                     /protein_end="351"
                     /protein_start="313"
                     /score="28.7"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQY"
     aSDomain        complement(2115..3005)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BW968_RS10180_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.40E-91"
                     /label="BW968_RS10180_Condensation_Starter.1"
                     /locus_tag="BW968_RS10180"
                     /protein_end="300"
                     /protein_start="3"
                     /score="298.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="HTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLLLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIP
                     FKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPD
                     QPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDT
                     IILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     CDS_motif       complement(2127..2216)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0003"
                     /evalue="1.30E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="BW968_RS10180"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.2"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       complement(2550..2615)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0002"
                     /evalue="1.00E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="BW968_RS10180"
                     /protein_end="155"
                     /protein_start="133"
                     /score="24.8"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNVMGNQIIDLY"
     CDS_motif       complement(2820..2936)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BW968_RS10180_0001"
                     /evalue="2.70E-08"
                     /label="C2_starter_024-063"
                     /locus_tag="BW968_RS10180"
                     /protein_end="65"
                     /protein_start="26"
                     /score="26.5"
                     /tool="antismash"
                     /translation="ICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLE"
     misc_feature    complement(3211..3224)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     gene            complement(3396..4871)
                     /gene="dacB"
                     /locus_tag="BW968_RS10185"
                     /old_locus_tag="SAMN05878487_2038"
     CDS             complement(3396..4871)
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389717.1"
                     /locus_tag="BW968_RS10185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2038"
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_076457962.1"
                     /transl_table=11
                     /translation="MKKSIKLYVAVLLLFVVASVPYMHQAALAAEKQDALSGQIDKILA
                     DHPALEGAMASITVRSAETGAVLYEHSGDTRMRPASSLKLLTAAAALSVLGENYSFTTE
                     VRTDGTLKGKKLNGNLYLKGKGDPTLLPSDFDKMAEKLKHSGVKVIKGNLIGDDTWHDD
                     MRLSPDMPWSDEYTYYGAPISALTASPNEDYDAGTVIVEVTPNQKEGEEPAVSVSPKTD
                     YITIKNDAKTTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWEPAGYALDL
                     FKQSLKKQGITVKGDIKMGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAEVLVKEM
                     GKVKKGEGSWEKGLEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQLLYDIQD
                     QSWFSAYLNSLPVAGNPDRMVGGTLRNRMKDTPAQGKVRAKTGSLSTVSSLSGYAETKS
                     GKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ"
     gene            complement(4905..5882)
                     /gene="galM"
                     /locus_tag="BW968_RS10190"
                     /old_locus_tag="SAMN05878487_2039"
     CDS             complement(4905..5882)
                     /EC_number="5.1.3.3"
                     /codon_start=1
                     /gene="galM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389718.1"
                     /locus_tag="BW968_RS10190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2039"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_038427744.1"
                     /transl_table=11
                     /translation="MANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNV
                     QLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFL
                     YHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVM
                     NKGKEAFPWGIGYHTTFIFPAESSLFSLTADQQWELDERLLPTGKLMDVPYKEALHEGM
                     DLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFNHWVVYNADGKQGYLC
                     PEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNHQ"
     misc_feature    complement(5973..5982)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            complement(6016..7407)
                     /gene="yoeA"
                     /locus_tag="BW968_RS10195"
                     /old_locus_tag="SAMN05878487_2040"
     CDS             complement(6016..7407)
                     /codon_start=1
                     /gene="yoeA"
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389719.2"
                     /locus_tag="BW968_RS10195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2040"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_038427746.1"
                     /transl_table=11
                     /translation="METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMM
                     AVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTL
                     TFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYTTFL
                     RGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMV
                     YLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGS
                     NATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGG
                     VLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRAGGTVLW
                     PTVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQI
                     TRLIQ"
     misc_feature    7452..7465
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.34"
                     /tool="antismash"
     misc_feature    complement(7599..7608)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            7694..8239
                     /gene="iseA"
                     /locus_tag="BW968_RS10200"
                     /old_locus_tag="SAMN05878487_2041"
     CDS             7694..8239
                     /codon_start=1
                     /gene="iseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389720.2"
                     /locus_tag="BW968_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2041"
                     /product="DL-endopeptidase inhibitor IseA"
                     /protein_id="WP_015714038.1"
                     /transl_table=11
                     /translation="MKKCLLFLTTIALILSLSTNAFAKNTSGDLSQKQALQLALSAREH
                     FWNTMSGHNPKVKKAVCPSGTFEYQNLQYVYMCSDLGTKAKAVNYLTPIFTKTAIEKGF
                     KDYHFTVSKGKLAVPIGDGDNLLNWKKSTAKLISKKGGTITYEFTVPTLDGSPSAKRKV
                     TFVKENKKWKVNQFDAVI"
     tRNA            complement(8333..8405)
                     /anticodon=(pos:complement(8370..8372),aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BW968_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN05878487_2042"
                     /product="tRNA-Arg"
     gene            complement(8333..8405)
                     /locus_tag="BW968_RS10205"
                     /old_locus_tag="SAMN05878487_2042"
     gene            complement(8458..9003)
                     /gene="yoeC"
                     /locus_tag="BW968_RS10210"
                     /old_locus_tag="SAMN05878487_2043"
     CDS             complement(8458..9003)
                     /codon_start=1
                     /gene="yoeC"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389721.2"
                     /locus_tag="BW968_RS10210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2043"
                     /product="site-specific integrase"
                     /protein_id="WP_076457963.1"
                     /transl_table=11
                     /translation="MHIVQPIRSLEKIQEVKQYLLNKNKRDYFLFIFGINSALRISDIL
                     PLQVKDVQNKDHLWATESKTKKKRKILILESLKQEIYDYTKDMKENEYLFKSVRTRKPI
                     SRIQAYRILREAAAACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSITMRY
                     IGIDEDTTRAAYKVFGGL"
     gene            complement(9319..9549)
                     /gene="yoeD"
                     /locus_tag="BW968_RS10215"
                     /old_locus_tag="SAMN05878487_2044"
     CDS             complement(9319..9549)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="yoeD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389722.1"
                     /locus_tag="BW968_RS10215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2044"
                     /product="excisionase family DNA-binding protein"
                     /protein_id="WP_076457964.1"
                     /transl_table=11
                     /translation="MYLSIEETAEYTNLSEDYIKSLVLEGKIRAVHDGEQFLIYKEQFK
                     THLEQLENYKALVQEILNEPIPEDIDVKDED"
     misc_feature    9642..9660
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.24"
                     /tool="antismash"
     misc_feature    9678..9694
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            9734..11497
                     /gene="ggt"
                     /locus_tag="BW968_RS10220"
                     /old_locus_tag="SAMN05878487_2045"
     CDS             9734..11497
                     /EC_number="2.3.2.2"
                     /GO_function="GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ggt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1274: gamma-glutamyltranspeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389723.1"
                     /locus_tag="BW968_RS10220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2045"
                     /product="gamma-glutamyltransferase"
                     /protein_id="WP_014476980.1"
                     /transl_table=11
                     /translation="MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGK
                     DGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKT
                     KDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGT
                     RSMKQLITPSIKLAEKGFPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQ
                     KDLAKTFKLIRSKGTDAFYKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQ
                     GYQIATTPPPSSGGIFLLQMLKILDDFNLSQYDVRSWEKYQLLAETMHLSYADRASYAG
                     DPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKV
                     EGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQP
                     NKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIY
                     TNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISIDHENGTFKGVADSSRN
                     GAAIGINLKRK"
     gene            complement(11661..12518)
                     /gene="yofA"
                     /locus_tag="BW968_RS10225"
                     /old_locus_tag="SAMN05878487_2046"
     CDS             complement(11661..12518)
                     /codon_start=1
                     /gene="yofA"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389724.1"
                     /locus_tag="BW968_RS10225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2046"
                     /product="LysR family transcriptional regulator YofA"
                     /protein_id="WP_076457965.1"
                     /transl_table=11
                     /translation="MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNI
                     RLFHRTNRGMKLTAAGENLLQYADQVLSLLDKAEKSTRMSRQPKGPLRIGSLETTAVTH
                     LPEHAASFLRRFPEVDLSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVSHDE
                     LVLISSREGTAEDMLQQPMLFFGAGCSHRDRVKRLLEEAGIDNQKIIEFGTLEAIIKGV
                     SAGMGTALLPKSSVDCSEHRTNVWIHQLPPAYQDLEIVFIYRKDFFITSAFQTFLDEIN
                     EMKR"
     gene            12647..13636
                     /gene="yogA"
                     /locus_tag="BW968_RS10230"
                     /old_locus_tag="SAMN05878487_2047"
     CDS             12647..13636
                     /NRPS_PKS="Domain: PKS_ER (15-324). E-value: 1.3e-39.
                     Score: 128.1. Matches aSDomain:
                     nrpspksdomains_BW968_RS10230_PKS_ER.1"
                     /codon_start=1
                     /gene="yogA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389725.1"
                     /locus_tag="BW968_RS10230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2047"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_015483300.1"
                     /sec_met_domain="ADH_N (E-value: 6.1e-13, bitscore: 43.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.6e-29, bitscore:
                     95.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDLF
                     LMKNKSEQDPHMILGSDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEIL
                     GGPSDGTLAEYVIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLI
                     PGIGSGVATYALLMAKAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKA
                     DVVLDSIGPALFSEYFRHVKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGE
                     EFQAMLAFIDKHKLRPVIDRIYPLEKACEAYKRMQEGRQFGNIGIVME"
     aSDomain        12692..13618
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BW968_RS10230_PKS_ER.1"
                     /evalue="1.30E-39"
                     /label="BW968_RS10230_PKS_ER.1"
                     /locus_tag="BW968_RS10230"
                     /protein_end="324"
                     /protein_start="15"
                     /score="128.1"
                     /tool="antismash"
                     /translation="SVQDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPHMILG
                     SDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEYVIIP
                     SQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLIPGIGSGVATYALLMA
                     KAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKADVVLDSIGPALFSEY
                     FRHVKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDKHKLR
                     PVIDRIYPLEKACEAYKRMQEGRQFGNI"
     gene            complement(13693..15174)
                     /gene="gltD"
                     /locus_tag="BW968_RS10235"
                     /old_locus_tag="SAMN05878487_2048"
     CDS             complement(13693..15174)
                     /EC_number="1.4.1.-"
                     /GO_component="GO:0009342 - glutamate synthase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0045181 - glutamate synthase activity,
                     NAD(P)H as acceptor [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389726.2"
                     /locus_tag="BW968_RS10235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2048"
                     /product="glutamate synthase small subunit"
                     /protein_id="WP_014476983.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.6e-27, bitscore:
                     91.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKPTGFMEIKREKPAERDPLTRLKDWKEYSAPFSEEASKRQGAR
                     CMDCGTPFCQIGADINGFTSGCPIYNLIPEWNDLVYRGRWKEALERLLKTNNFPEFTGR
                     VCPAPCEGSCTLAISDPAVSIKNIERTIIDKGFENGWIQPRIPKKRTGKKVAIVGSGPA
                     GLASADQLNQAGHSVTVFERADRAGGLLTYGIPNMKLEKGIVERRIKLLTQEGIDFVTN
                     TEIGVDITADELKEQFDAVILCTGAQKQRDLLIEGRDSKGVHYAMDYLTLATKSYLDSN
                     FKDKQFIDAKGKDVIVIGGGDTGADCVATALRQKAKSVHQFGKHPKLPPARTNDNMWPE
                     QPHVFTLEYAYEEAEAKFGRDPREYSIQTTKMVADKNGKLKELHTIQMEKVKNEHGKYE
                     FRELPGTEKVWPAQLVFIAIGFEGTEQPLLKQFGVDSVNNKISAAYGDYQTNIDGVFAA
                     GDARRGQSLIVWAINEGREVAREVDRYLMGSSVLP"
     misc_feature    complement(15143..15156)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            complement(15191..19753)
                     /gene="gltB"
                     /locus_tag="BW968_RS10240"
                     /old_locus_tag="SAMN05878487_2049"
     CDS             complement(15191..19753)
                     /EC_number="1.4.1.13"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gltB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389727.2"
                     /locus_tag="BW968_RS10240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2049"
                     /product="glutamate synthase large subunit"
                     /protein_id="WP_076457966.1"
                     /transl_table=11
                     /translation="MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHDIVKQGLKM
                     LCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKDINLPEKERYGVGMVFFSQKEDE
                     RKKIEKQINALIEQEGQVVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGASSDLKDNLS
                     FERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSA
                     FALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNK
                     ILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHS
                     SLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVL
                     YKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDPESREEEQF
                     SDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQSLFNYFKQLF
                     AQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSNEQFYALKTIV
                     HPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNERLTPIPPLLAV
                     SALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLAYATYKQEIDEGR
                     LDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFTGTA
                     SQLGGIDLQTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWA
                     CRRNDYNLFKQYTKAADEERIGFLRNLFAFDGNRKPLKLEEVESAESIVKRFKTGAMSF
                     GSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDRRSAIKQIASGRFGVKS
                     HYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIE
                     DLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTS
                     IKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAP
                     LVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGF
                     KTFDEMIGRTDVLHVSERAKEHWKASQLDLSTLLYQPEGVRTFQSPQNHKIDQSLDITT
                     ILPAVQEAIESGKEADISIEINNTNRVAGTITGSEISKRYGEEGLPEDTIKLHFTGSAG
                     QSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSPEGFNSASDDNVIIGNVAFYGAT
                     SGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGDVGKNFAAGMSGGI
                     AYVLTEDVKAFKRKCNLEMILFESLEDEKEIQQIKAMLERHTAYTNSQKAEDLLDQWED
                     SVKKFVKVIPKNYKQMLASIEEQKAAGLSDEEAIMFAFEANTKPKQNTAASGQKQAVVQ
                     "
     misc_feature    complement(19866..19880)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            19900..20802
                     /gene="gltC"
                     /locus_tag="BW968_RS10245"
                     /old_locus_tag="SAMN05878487_2050"
     CDS             19900..20802
                     /codon_start=1
                     /gene="gltC"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389728.2"
                     /locus_tag="BW968_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2050"
                     /product="glutamate biosynthesis transcriptional regulator
                     GltC"
                     /protein_id="WP_004399246.1"
                     /transl_table=11
                     /translation="MELRQLRYFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELNV
                     TLFEREGRNIKLTPIGKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQ
                     LLPTVISAFKEEYPHVEFLLRQGSYKFLIEAVRNRDIDLALLGPVPTNFSDITGKILFT
                     EKIYALVPLNHPLAKQKTVHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLVSTEG
                     EDLDAIKGLVSAGMGVTLLPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNRELAPS
                     ANDFYEFVIQFFSKLEQYQ"
     gene            complement(20854..21969)
                     /gene="proB"
                     /locus_tag="BW968_RS10250"
                     /old_locus_tag="SAMN05878487_2051"
     CDS             complement(20854..21969)
                     /EC_number="2.7.2.11"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389729.1"
                     /locus_tag="BW968_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2051"
                     /product="glutamate 5-kinase"
                     /protein_id="WP_042975927.1"
                     /transl_table=11
                     /translation="MTPDTSMKRVVVKIGSSSLTSLHGEISIRKLEALVDQVVKLKDAG
                     YEVILVSSGAVAAGYRKLGFIQRPEKLPEKQASASIGQGLLMEAYSKLFLAHGYVASQI
                     LITRSDFSDEYRYNNVRNTMNVLLERGIIPIINENDTVTVNRLKFGDNDTLAAKVAGLI
                     DADMLVILSDIDGLYDGNPRTNPEAKRIQRVSEITPDIEACAGDTGSIVGTGGMRSKLD
                     AFKIVMASGIKGFLGQADAGDILYHAVHEQAEGTYFEAEGTLPLNQKEQWIAFNSGPEG
                     EMILSDDCSRKITNGQSSLYLDGVQKIKGKFKSGSVVRLMDSKGTEIGLGIVNYSSVQL
                     QEPEKKKELTNRALIDQEAFVCHVDFSLPVN"
     gene            complement(21966..22859)
                     /gene="proC"
                     /locus_tag="BW968_RS10255"
                     /old_locus_tag="SAMN05878487_2052"
     CDS             complement(21966..22859)
                     /EC_number="1.5.1.2"
                     /GO_function="GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="16.11: Scavenge (Catabolism)"
                     /function="16.2: Construct biomass (Anabolism)"
                     /gene="proC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389730.2"
                     /locus_tag="BW968_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05878487_2052"
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="WP_010886524.1"
                     /transl_table=11
                     /translation="MRTKKRTKEMLPIFDQKKVAFIGAGSMAEGMISGIVRANKIPKQN
                     ICVTNRSNTERLTELELQYGIKGALPNQLCIEDMDVLILAMKPKDAENALSSLKSRIQP
                     HQLILSVLAGITTSFIEQSLLNEQPVVRVMPNTSSMIGASATAIALGKYVSEDLKKLAE
                     ALLGCMGEVYTIQENQMDIFTGIAGSGPAYFYYLMEFIEKTGEEAGLDKQLSRSIGAQT
                     LLGAAKMLMETGEHPEILRDNITSPNGTTAAGLQALKKSGGGEAISQAIKHAAKRSKEI
                     SEDIEKTAAPLSGVIK"
ORIGIN
        1 cgtgagacaa gcgccgttgc ttttaaggaa tgtcccccgc ggtcaaaaaa gttgtcgtga
       61 atcccgacag ggccattttt cagcacgtcc tcccatagct gagaaagttt catctcagtc
      121 acgtttctcg gcgccgtgta ggtctccgca tctgccgctc cgctaggagc tggcagggcg
      181 tttcggtcga gctttccgct tggtgtaacc ggccactgtt ccatctctat catataggct
      241 gggaccatgt agcccggcaa cagtctctca agctgcgctc ggatttcgtt tctttggagc
      301 ccttctacat aagcgcataa ttccggctcc ccgctgtctg tccgtacggt aacggccgcc
      361 tctcttacac cttctatatt tcttagtgcc gcttcaattt ctctcggctc aatccggtag
      421 ccgcggattt tcacctgatc atccgtgcgc ccgaggaatt caatattccc gtcagggagc
      481 cagcgcgcca catcccctgt tttgtacatg cgttcccccg ggtaaaacgg gtcttctaga
      541 aaacgctcct ccgttaatgc cggccgattc aaataacctc tggcaacacc cgctccggca
      601 atgtacagtt cgccggcgac accagaaggc tgtacggcta aatgcggatc taaaacatac
      661 aaacgcgcac cgggtacggg cttcccaatc ggaatccgca aacggtccct gtcccgttct
      721 gggtccaaca cgtaaaatgc cgcgtctacc gttgcttctg tcggcccgta accatggatt
      781 aatgatacct gcggcaatac agaagcaaaa cgggctgccg tacgcggcgc aagcggttca
      841 cctccggcga atacacgctt taggtttgtc ccgtcaccga gcgctaacat ttccgcttga
      901 tctagaaagc tgttcagcat agccggaata aaatgagccg ttgtcacgtt ttcctgatga
      961 atggcttgta cgatcaacgc ggggtctttt tcccaaccgg gcggaagcag atacgccgaa
     1021 gcaccggaaa gagtccacca aaacagctgc cacacagacg catcaaagga aaaagaggtt
     1081 ttcaccatga caatgtcatc ttccgaaagc ggaaactggt gctgcatgcc ggtcagaaaa
     1141 gaaacagcct ggcggtgctc aacggccact cctttcggct gtccggtgga ccccgacgta
     1201 taaatgacat aggcgagaga tccgtcgcta acagaagcag acacataacg ttttacttct
     1261 tcacgctcaa gagatgtcat gtccacttca agcgtttcgc cagaaaagtt tggtgcggag
     1321 catcccggct gcgtcagcaa gagtgatgcc ccgctgtctt tcagcatgta gctcagccgc
     1381 tcctttggat acgcaggatc aagcggcaaa tacgcccctc cggccttcaa tacagcaagg
     1441 acagcgatca gcatgtcagg tgagcgttca gacaggacac cgacgatact ttcgtttgtg
     1501 acgccgcgtg ccgcaaggtg cgcagccagt cggctggcgt acatatcaag ctcagcgtat
     1561 gtcagcgaac cgcctgaaaa gcgaatggcc agccgctccg gtgtggaagc tgcctgttgc
     1621 tcaaacagcc catgcagggt gaaagcttta ggcgaaacag cttccgtctt gttaaactca
     1681 tacaacaatt tttgcttttc tcttgtattc gtcatatcta attctcttat aaagctgtgc
     1741 ggatgttgaa gggcgttttc cagtatggta agcaaatgag attgtattcg tttaatatcc
     1801 tcaagagaaa acaaggtatt ttgatagtcg aaatttaatt gaatggttcc attgtctatc
     1861 cgttcttgta tttgaactga aagctcattc gcagtgtatc cgctgaaata aagcgctgtt
     1921 tcatagtcaa aatcatctgc attgtgccac tgaagtggct gatactgcat agatataccg
     1981 ataaggttgt gtaaatcctt ctgttcattt cttaattcat ttacaagcaa attataagga
     2041 aaccgttgat gacgcataac agaaagctgt tccctgccta ttgtgcggac aaaggaaaga
     2101 aaatctgtgt caggatcaac cgttattctg attggaaggg aactaacgaa catgccgagc
     2161 atttcttttt cagcctttga acctctgttg ccatagtagg tgccaatggc aagatctttt
     2221 ttagaagtga ttcggctgat gcatatgtaa aatgaagcca taaataagga aatgatattg
     2281 atcttgtgtt cttcgcagaa gattcgaatc gtttgctcta gatcaggtga aagaatgatg
     2341 gtgtctctgg atgcagatgt gctctgtttt tgtaaggacg tctggtcggc taacgagtgg
     2401 tattccaacg ggtgctcaaa ggtttgtgtc caaaataaac ggtcctttgc aaaccgtgga
     2461 gattgtagat attgactctc tttttcgatg tagctcaagt aagaaggttc cggctgatca
     2521 ggtaaaggat ctttcttttt cattttttga taaagatcta taatttgatt tcccatcaca
     2581 tttaaagaga ttccatccat tatgatatga tggaatttcg caaatagcca aacttcatga
     2641 gagtcaattc taaggaggta aaattgaaaa agaggcgagt tgaacagttt aaatggaatg
     2701 ctcgcttgat cctgaatcca ttgctctatt tctatcattt caacatttga aaaatcaatt
     2761 attctaagtg gataatattt atattcagta aggagcaatc gcggctcaag ctcttctcct
     2821 tctaacagct gaaatctaat ggcgtcgttg cgggagatgg aatgattcag tgctccctcc
     2881 agagtatcaa gctcaatatt gcctttaaat ttcacacagg ctgtgagatt gcaaatgctg
     2941 gtatctggct ccagcagttc ggtaaaccac actctccttt gggcatgggt taaagaataa
     3001 gtatgttcgc tcaatggatt ccctccagtt ctcataataa gaggataaga aaatgtagaa
     3061 aaaagcagaa aaatgacaat aaaagaaatt atatgactat ataatccata tatgcactat
     3121 attaacggat attttttaaa gtacaataaa aaacattaaa tttttataac atttttttga
     3181 atatagtatt atttctttat ttttcgtttc tttttttatc aaatttccgg atataaagtg
     3241 ataaaagtat tgttttacat aaggtcttat acactacttt ttaatcggac taattttctt
     3301 ttgtgcatca ttcttctaat tgttggaagg ttcgacaaag cgttattaca gacataaaaa
     3361 aacctgtttt ctcttggaaa acaggtctgc cgctattatt gatttgccaa aatgacagcg
     3421 atttgatcct caatatcttt tccatcctct tcatcaatca atccatttag aagaatagag
     3481 aaaacaagtt tttttccgct ctttgtttct gcgtaccccg atagagagct taccgtactg
     3541 agcgatccgg tttttgctct tacttttcct tgtgcaggag tgtctttcat gcggtttctc
     3601 agcgttccgc ccaccattct gtcaggattg cccgcaacag gtaaagaatt tagataagcc
     3661 gagaaccaac tctgatcctg aatgtcatat aacagctgtg aaagttgatc tgaggataca
     3721 gcatcaatat gtgagattcc tgatccgtcc cttaagacga gtgatttaga atcaacacca
     3781 aattccggaa gcgtactgtt taacacttcg agcccctttt cccagctccc ttctcctttt
     3841 ttcactttcc ccatctcttt tacgagcact tcggcatgtc cgttattact taatttcatg
     3901 aacggcacaa aaagtttcga taaaggcatt gagcgatgag agagcagcac atctgaagaa
     3961 ctaggtgctt cacccatctt gatgtcccct ttcacagtaa taccttgttt ttttagtgac
     4021 tgcttaaata aatctaaggc atatccggca ggctcccaga cagaaatcca ttcctttgtc
     4081 ttgtttgcgt caaccggtac gctcccttca attgtaatcg tgtttgttcc atgttctctt
     4141 tcgattgtga ggtctttctc tgaaccggca gcagtcgttt tagcatcgtt ctttatcgtt
     4201 atataatcgg ttttcggaga gacagacacg gcaggctctt ccccttcttt ttgatttggg
     4261 gtgacctcaa caatcacagt gcctgcatca tagtcttcat tcggagacgc tgttagagcg
     4321 gagattggcg cgccataata tgtgtattca tcgctccaag gcatatcagg tgataatcgc
     4381 atgtcatcat gccacgtatc atcaccgatc agattgcctt taattacttt tacgccggaa
     4441 tgtttcaatt tctcagccat tttgtcaaaa tcagatggta aaagtgtcgg atcgcctttg
     4501 cctttcaaat aaaggttacc attcagcttt ttccctttca gtgttccatc cgtccggacc
     4561 tcggttgtaa aagaatagtt ctcgccaagg acagaaagtg ccgcggctgc tgtcaaaagc
     4621 tttagagaag aggcaggcct cattcgggtg tctcctgaat gttcatatag aacagcacct
     4681 gtttccgcag agcgaacggt gatgctggcc attgcgcctt cgagggcagg atgatcagct
     4741 aaaatcttat cgatctgccc ggaaagtgca tcttgttttt cagcggcaag cgcagcctga
     4801 tgcatataag gcaccgaagc aacgacgaaa agcagtaaaa cagcaacata aagctttatg
     4861 ctttttttca ttaatttccc cgcctctctg cgcttcatca ttagctattg atgattcagt
     4921 tcaatggtga tactgctttt agctgtcgtt tcttctcccg gctccagcac ttgtaaacca
     4981 gtgagtgacg aaggtaaatc aagattcact gcgtttgtca cccatgtgta aggttcaggg
     5041 cataaatacc cttgttttcc gtccgcattg tatacaaccc aatggttaaa ctgttcatct
     5101 gccttataaa taatgctgat atgtgcatgc tgatgataaa tgactgcctg gttttctccg
     5161 cccctcttct gataagaaga taaaaagaca tcatccagct gcttgtggcg caaatccatt
     5221 ccttcatgca aagcttcttt atacgggaca tccatcagct tcccggtcgg cagcaggcgt
     5281 tcatccaact cccattgctg atctgctgtc agggagaata acgagctttc tgccggaaat
     5341 ataaatgtag tatgataacc aattccccaa ggaaacgctt cctttccttt gttcatgacc
     5401 gtcgcatgtt taaatagggt attctccttg atcgtgtatg tcatccgaac gacggcatga
     5461 tgaggaaatt gcttctgcac atggggaagc tcagaaagat caatttctgt ttcaacaatc
     5521 actccttcat cagtttgctt cgtggtcacg acattccact tttcatggta aagaaacccg
     5581 tgaagatggt tgtgtttatc cttctcgttg atatcaaaat gatacgttct gccccggaaa
     5641 ctgaatgtac cgtcacttat gcggttaggc gggaacagga ttggaatgcc atacaatgtt
     5701 ggtgtgtcgt gaaaactttc tgctgtttcc ggttcacgca aaagctggac atttgttgtt
     5761 ttgtccacga gagaaatgac gttgctcccc cactcaggga caacaatcat ttctagatgt
     5821 tcgttgcccg ctttgatggc cggcgttccc aaatacgtga ttttctcaat aaagtttgcc
     5881 atgtttactc aacctctcct tgattcattg ctagtataag aattcaatgt actgtaccat
     5941 atttcctcca ttttatattt tcccctatca aataaaaaaa caccgttcaa acttatgaac
     6001 ggtgtgattc ggaggctatt ggatgagacg tgtgatttgt ttctttttcc agacgaattg
     6061 ataataccca taaatcaaca gcaagctgac ggcaaacgca gctggataac caacccagac
     6121 gccgagtatt tcaagctttg tatagtgaga aaggacgaaa gcgacaggca cctctactcc
     6181 ccagattgca aaaatactga tgacggtcgg ccataaaacc gttccgcctg cccgcatcgt
     6241 tgcagaaata atttgggcat ttccaaacag caaatagctc cacagtgtaa tcatcaaaag
     6301 acggtgcgca atgtaaagcg tctcttgctc ggttaaaaat aacgataaaa tctgatgtga
     6361 aaaaacatag atcagaatga tcagtacgcc gccaatgata taattcagcc aaatcccaac
     6421 gcgaatgacc tgctttaagc ggtcaaactc gtttgcccca atcgattgcg cagcgaaaat
     6481 agaaaccgca ataccaaggc tgacggccgg catctgtaca tagctggcca cctggttgac
     6541 cactccgtat gcagctgttg cattagagcc gtaatgattg acgaatgaaa taaccgctat
     6601 ctctgataat gagacaagaa tcatattgat gcttgctggg accccaagac gcagcaggag
     6661 aaccagcagt tccttatcca ttttcaaata acgacgcact gttttatcaa attgcagcgg
     6721 gtgttttcgc tttcgtaaat acaccattaa cacgagaaaa gtcgcaatcg tggaaatgac
     6781 agttgcatat gccgagccgt atatgcccag tttcggaaaa ccaaacatgc caaggattaa
     6841 aacaggcaaa agcgcgatgt tgatgaccgt gctcacaatc agcgtataaa acggtgtctt
     6901 agaatcccct gttccgcgca aaaaggtagt atatgcaaaa tataaaaaca taaacggcat
     6961 agcataaaat aaaatacgtg catagttagc gctgacatga atgacatttt caggcgttcc
     7021 cattaaacga aggatatcca gggtgaaaat actgccgatg acggctaaca caacgcctaa
     7081 taaaaatgta aacgtgagcg tcgtcccgac aacagccttt agccgttcct catttttcgc
     7141 tccgtaagct tgtccgatca gaatcgaact acctgaaccg atcccaatcg taaatgagat
     7201 taaaagaaaa aataacggga aaaaggatga tacagctgcc actgcatcaa caccgagcca
     7261 tctgcctaca gccatcatcc cgactagctg gccgactgat tgcagcacat tgctcagcag
     7321 aagcggcacc aaaaagagtg acatcgaccg ccaaactgat ggtttgcttt tcttttgagt
     7381 tacaagaggt tcttgtgatg tttccatatt aaaggactcc tttatttgaa atcgttttta
     7441 aacatgccct cattttttga caaaaacagg atatgcaaca tgttattatt catcactgca
     7501 catatgaaac ccttcccgat tcttctaatt ttacacatct ttttagctta tgaagaataa
     7561 actagcaagt aatggcgtat tttttgtgag taaaagaata aaaaaataat ttatgcaaaa
     7621 gtattgtaat ctatccgtaa ttattgtaac atttgtaaca taagagaaag agattttgaa
     7681 ggagagagcg ataatgaaaa aatgtcttct atttctaaca accattgcac ttattctgtc
     7741 attaagcaca aatgcatttg cgaaaaatac atcaggcgat ttatcacaaa aacaagcatt
     7801 acagttggca ttatccgcta gagaacattt ttggaacacc atgagcggcc acaatccgaa
     7861 ggtgaaaaaa gcagtttgcc catcaggcac attcgagtat caaaatcttc aatatgtata
     7921 catgtgcagt gatctaggca ctaaagcaaa agcggtgaat tatttaactc ctatttttac
     7981 aaaaacagca attgaaaaag gctttaaaga ttatcatttc actgtttcaa aaggaaaact
     8041 tgctgttcca atcggtgacg gagacaatct tttgaattgg aaaaaatcaa ctgctaaact
     8101 gatctctaaa aaaggcggca caatcacata cgaatttacc gtccctacat tagacggatc
     8161 cccttctgca aaacggaaag taacattcgt gaaagaaaat aaaaaatgga aagtcaatca
     8221 atttgacgca gttatataag aaaaacgccc ggtataagcg ggcgtttttt atttggtttg
     8281 cataaagaaa gacaacaggc gaaaagtgcc tgttgtcttt ttgtgaatat aacgctctag
     8341 gagagattcg aactcccgac ctgcagttta ggaaactgct gcactatccg ctgtgctact
     8401 agagcttttg gtatttatat agtagctctg atgatcaata ttttcaagcg atttgtatta
     8461 aagccctcca aaaaccttat atgcggctct tgtcgtatct tcatcaatac cgatataccg
     8521 cattgtaatt gatggtgatg aatgattcag tattctctgc agctcggcga tgtctttcgt
     8581 tcgctgataa aaatgatagc caaacgtttt ccggagtgta tgcgttccta tctcctcaag
     8641 tccgcacgcc gcagcggcct ctcttaaaat tctgtaggcc tgtatgcggg aaattggctt
     8701 cctggtccgc actgatttaa aaagatattc gttttccttc atgtctttcg tataatcgta
     8761 tatttcctgt ttcagcgatt ctaaaataag aatctttctt ttctttttcg ttttgctttc
     8821 agtcgcccat aaatgatctt tattttgaac gtccttcact tgcagcggca gaatatcaga
     8881 aatgcggagc gcgctgttaa tgccgaaaat aaacagaaaa taatcccgct tgtttttgtt
     8941 aagcaaatac tgtttgactt cttggatttt ctctagactg cgaatcggct gtacaatatg
     9001 catcaaaaaa ctccttaaaa accgttatgt aacattttga ggtctatgtt actattatag
     9061 ctgaaaaacg ttgaatgtca aagtgcggcg gcatttatgt aacataatat acatagtgtt
     9121 acataagctt ttaaaaaagc ttcttccaac cttcacccta taaaataagc tttaaagcct
     9181 attttaaagc ttttaacctc ttggatactt attcccctac taatcatcaa aaaacctctt
     9241 aaaacgaaat ctgacactcc caattttctg gagcttccgc aaaaatatac aaaaaaagac
     9301 acaatttcaa atcgtgtcct aatcctcatc ctttacatca atatcttccg ggatcggttc
     9361 atttaatatt tcctgcacca gtgctttgta attctccagc tgttcgagat gcgttttgaa
     9421 ctgttcctta taaatcaaaa attgctcccc gtcatgaacg gctctgattt tcccttcgag
     9481 caccaagctt ttaatataat cctctgaaag atttgtatat tctgctgttt cttcaatcga
     9541 taaatacata tagcagtccc ttcttaatcc gtatgctgat tctaatatag cacatggctc
     9601 atatcaatat aatcaatttt gcacagaaaa acggctttat gtactatata atataccatt
     9661 tgtcacttgt gaaaacgctg taattttttt acgctaagat tgtaacaata cagcttcata
     9721 taggagggag aacatgaaaa gaacgtggaa cgtctgttta acagctctgc ttagtgttct
     9781 gttagtcgct ggaagtgtcc cttttcacgc ggaagctaaa aaaccgccca aaagctacga
     9841 tgagtacaaa caagtagatg ttggaaaaga cggcatggtt gcgaccgcac atcctcttgc
     9901 ttctgaaatc ggtgctgatg tgctgaaaaa aggaggaaat gctattgacg cagcggttgc
     9961 cattcaattt gcactcaatg taacagagcc gatgatgtca ggtattggcg gcggcggttt
    10021 tatgatggtg tatgacggaa aaacgaagga tacaacgata atcgacagcc gtgagcgtgc
    10081 tccagcaggc gcaactcctg atatgtttct ggacgaaaac ggcaaagcaa ttcctttctc
    10141 tgaacgtgta acaaaaggta ctgccgttgg tgttccaggc acgctgaaag ggctggaaga
    10201 agccttggat aaatggggaa cccgttcgat gaagcaatta attacccctt ctattaaact
    10261 cgctgaaaaa ggctttccga ttgattctgt gttggcagag gccatttctg attatcagga
    10321 aaaactttca cggactgccg caaaagatgt atttttacca aatggcgaac cgcttaaaga
    10381 aggagatacc cttattcaaa aggatttggc taaaacattt aagcttattc gctccaaagg
    10441 cactgacgct ttttataaag gaaaattcgc caagacgctt tctgacactg tccaggattt
    10501 cggcggatca atgacagaaa aagatttaga aaattacgac attacaattg atgaaccgat
    10561 ttggggagac tatcaaggct atcaaatcgc tactactcct cctccaagct ccggcggtat
    10621 tttcttattg caaatgctga aaatccttga tgattttaac ctttcacaat acgatgtccg
    10681 ctcatgggaa aaatatcagc tgcttgctga aacgatgcat ttgtcttatg ccgaccgtgc
    10741 gtcttacgca ggtgatcccg aatttgtaaa tgttcctctc aaaggcttgc ttcaccccga
    10801 ttatattaaa gaacgccagc aattaatcaa cctagatcaa gtgaataaaa aaccgaaagc
    10861 cggtgaccct tggaaatacc aagaaggatc agcaaactat aaacaagttg aacagccgaa
    10921 agacaaagta gaaggccaaa caacccactt tacagttgct gatcgatggg gaaatgttgt
    10981 ttcttataca acaacaatcg aacagttgtt tggaacgggt attatggtcc ctgattacgg
    11041 tgtcatccta aacaacgaat taacggattt tgatgcgata ccaggcggag ctaacgaagt
    11101 acagccaaac aaacggcctt taagcagcat gaccccgacg attttattta aggatgacaa
    11161 gcctgtcctc actgttggat ctcctggcgg ggctacaatt atttcatccg ttttgcaaac
    11221 cattctctac cacattgaat atggtatgga attaaaagca gctgttgaag agccgagaat
    11281 ttatacaaac agcatgagct cttaccgtta cgaagacgga gttcctaaag atgtcctcag
    11341 caagctaaac gggatgggcc acaaattcgg cacaagtccg gtggatatcg gaaacgtgca
    11401 aagcatatcg atcgaccatg aaaacggcac ctttaaaggt gtagctgatt caagcagaaa
    11461 cggagcggcg atcggcatta atttaaaacg caaataaata aaaaaactgt actcgcttca
    11521 attgagtaca gtttttttat gcagatcttt aataacaacg ggcattgctg atgctctgta
    11581 tccctgattg caatccaaaa tgacagaatg atgactgctt ctgtgacaaa cgtctttatt
    11641 ctgctaatgc acgtctatct tcatcttttc atttcgttta tctcatcaag aaatgtctga
    11701 aacgcactcg taataaaaaa gtctttcctg tatataaaga cgatctctaa gtcttgatat
    11761 gctggtggca attgatgaat ccatacattt gtacgatgct cggagcagtc aacagaggac
    11821 tttgggagca gcgccgtacc catcccggcg gaaacacctt ttataatagc ctccaatgta
    11881 ccaaactcta tgattttttg attgtctatg cctgcttcct ctagtaatct tttgaccctg
    11941 tcacgatgag aacagccagc cccaaaaaag agcatcggct gctgaagcat gtcttctgcc
    12001 gtcccttctc gtgatgaaat caaaactaat tcatcatggg aaacatggag ttgtctaact
    12061 gcagcgtgtt caaccggccc atatacaaaa gcgccatcaa ctttatgatc aagaacctgt
    12121 tgaatcaaat gatgcgtatc agctgtgttc actgataaat ccacttcagg aaaacgcctg
    12181 aggaaggatg ctgcatgctc aggcagatgc gttaccgccg tcgtttccag tgatccgatc
    12241 cgcaaaggcc cttttggttg cctgctcatt cgggtcgatt tttcagcttt gtctaacagc
    12301 gataatactt gatctgcata ttgtaaaaga ttttctcctg cagcagtcag cttcatcccc
    12361 cgattcgttc gatgaaaaag cctgatattc aaatcttcct caaggttatg cactctggct
    12421 gtcacattcg actgaacata attcagcatt tgggctgctt tcgttatgct tccttcgcgg
    12481 gcgacagcct gaaaaatctt taaatctccg ctttccacgc gctctcacct gcttgctatg
    12541 atgaaaagtg atattggcta tcatatttgt tcattttact cgaagaaaac cgctatgtaa
    12601 aatatgtaaa gatatgaaaa tacaattcaa tgaggaggca gacagcatga aagctgtaat
    12661 tcacaacgga aaagccggtc ttctggggtt atcagttcag gacgttccat caacaaagcc
    12721 tggatacgga gaggtaaagg ttaaattgaa atccgcgggc ctgaatcatc gtgacttgtt
    12781 tcttatgaaa aacaaatctg aacaagatcc tcacatgata ttggggtctg acggcgcggg
    12841 tatcatcgaa gagattggtg aaggcgtgaa aaatgttact gttcagacag aagtagtcat
    12901 tttcccgaca ttgaactggg atttgacaga gaatgtacca cctgtacctg agattctggg
    12961 aggtccttcg gacggaacac ttgctgaata tgtgatcatt ccttcacaaa atgcaatcaa
    13021 aaaacctgct tatttatctt gggaagaagc gggcgttcta cctttatccg ctttaaccgc
    13081 atatcgggct ctgtttacaa aggggcaatt aaaaaaaggc gagcatctat tgatacccgg
    13141 catcggcagc ggggttgcaa cctacgcttt attgatggct aaagcgattg gggcaacagt
    13201 aagcgtgacc tcccgcagtg aggagaaaag aaaaaaggcg ctgaaattag gtgctgatta
    13261 cgcatttgac agctacagca attgggatga gcagttgcag ggaaaaaagg cggatgttgt
    13321 tcttgacagc ataggacctg ccctcttttc ggaatacttc cgccatgtaa aaccaaatgg
    13381 ccgtattgtc agctttgggg caagctcagg ggataatctc agttttccgg tgcgttctct
    13441 attctttcct caggtcaatg ttttgggaac ctcgatggga agcggtgagg aatttcaagc
    13501 tatgctcgct ttcattgaca aacataagct gcggcctgta attgaccgga tatatccttt
    13561 agaaaaagca tgtgaagcat ataaaagaat gcaggaaggc agacagtttg gaaacatcgg
    13621 aatcgtaatg gaataaaaaa agaaaccggc tggcagccag accggtttct cttatatgat
    13681 aatccccttt atttacggaa gaactgaact ccccatcaaa tatcgatcca cttcacgcgc
    13741 cacttcacgg ccttcattaa tcgcccatac gattaagctt tgccctcttc ttgcatcccc
    13801 tgcggcgaat acaccatcga tatttgtttg ataatcccca tatgctgcac tgattttgtt
    13861 atttactgaa tcaacaccga actgtttcaa cagcggctgt tctgtgcctt caaagccgat
    13921 agcgataaag acaagctgag caggccatac tttttccgtt ccaggcagct cgcggaactc
    13981 gtattttcca tgctcatttt tcactttttc catttggatg gtatgaagct ctttcagctt
    14041 tccgttttta tccgcaacca tttttgtcgt ttgaatggag tattctctcg gatctcttcc
    14101 gaattttgct tctgcttcct cgtatgcata ttcaagcgta aagacgtgtg gctgttcagg
    14161 ccacatattg tcattcgtgc gggctggcgg aagtttcggg tgtttgccga attggtgcac
    14221 gcttttggct ttttgacgca gagcggtagc cacacagtca gctcctgtat ctccgcctcc
    14281 gattacgatg acatccttcc ctttagcatc aatgaattgc ttgtctttaa aattagaatc
    14341 taaatagctt tttgttgcaa gtgtcaggta gtccatcgcg taatggactc cttttgagtc
    14401 gcgtccttca attaagaggt cccgctgttt ttgagcgcct gtgcatagga tcacagcatc
    14461 aaattgctcc tttagctcat cagctgtaat gtcaacaccg atttctgtgt tcgtgacaaa
    14521 atcaattccc tcttgcgtca gcaatttaat tcggcgttct acaatgccct tctcaagctt
    14581 catgtttgga atgccgtatg ttaaaaggcc gcccgctctg tctgctcgtt caaaaacagt
    14641 gacggaatgc cccgcttgat tcagctggtc agcactcgcc agtccggctg ggcctgaccc
    14701 gacgatagca acttttttgc ctgttcgttt ttttggaatt ctaggttgaa tccagccgtt
    14761 ctcaaatcct ttatcgataa tggtccgctc gatgttttta attgatacgg ccgggtctga
    14821 aatcgctaaa gtgcatgatc cttcacaagg agcgggacat acccgccctg tgaattcagg
    14881 aaagttgttt gttttcaaca gacgttccaa tgcttccttc catctgcccc ggtagacaag
    14941 atcattccat tcaggaatta agttgtaaat cggacagccg gatgtaaatc cgttaatgtc
    15001 cgcaccgatc tggcaaaacg gtgtaccgca atccatacac cgcgcccctt gccgtttcga
    15061 tgcttcttct gaaaaaggag cagaatattc tttccaatcc tttaagcgag tgagagggtc
    15121 ccgctccgca ggtttttctc gtttgatctc cataaatcca gttggtttcc ccatgttcct
    15181 ctccccttcc ttactgtact accgcttgtt tttgtcccga tgctgctgta ttctgctttg
    15241 gcttcgtgtt ggcctcaaaa gcgaacatga tggcttcttc atctgataaa cctgcagctt
    15301 tttgctcttc gatgcttgcg agcatttgtt tatagttttt cggaatgact ttgacgaatt
    15361 ttttcacact gtcttcccat tgatctagca gatcttctgc tttttggctg tttgtatacg
    15421 cagtatgtct ttcaagcatt gctttgattt gctggatttc tttctcatcc tctaatgatt
    15481 caaataaaat catctcaagg ttgcatttgc gtttaaacgc tttgacatct tcggtcagta
    15541 cataagcgat tccgccggac atacctgccg caaagttttt gcctacatca ccgagaacga
    15601 caacgctgcc gccagtcatg tattcacagc cgtggtcgcc gatgccttct acaactacgt
    15661 tcacaccgct gtttcgaacg gcaaagcgtt caccagcacg cccgttaata tatgcttctc
    15721 cgcttgtcgc accgtaaaaa gccacgttgc cgataatgac attgtcatcc gaagcagagt
    15781 tgaatccttc tggtgacttg acgatgattt ttccgccaga aagccctttt ccgacgtaat
    15841 catttgagtc tccgtccaaa taaagcgtca tccctttagg aacgaaagct ccaaagcttt
    15901 ggccggctga tccggtaaag tgcagcttga ttgtatcttc aggaagacct tcttctccgt
    15961 aacgctttga gatttcactg ccggttatcg ttccggctac acgatttgta ttattgattt
    16021 caatcgaaat atcagcttct tttccagatt cgatggcttc ttgtacggcc gggagaattg
    16081 ttgtaatatc aagtgattga tcaattttat gattttgcgg cgattggaac gtccgcaccc
    16141 cttcaggctg ataaagaagg gtagacaaat caagctggct tgctttccag tgctcctttg
    16201 cccgttcact tacatgaagt acatcagtgc ggccgatcat ttcatcaaat gtcttgaagc
    16261 ctaacgcagc catgtactca cgaacttctt cggcaatgaa cagcatatag ttcacaatat
    16321 ggtcaggatc tcccatgaac tttttgcgaa gctctggatt ttgtgtcgct acaccgacag
    16381 ggcatgtatc caaatggcag gcacgcatca tgacacagcc gagtacaact aacggagccg
    16441 ttgcgaaacc aaattcttcg gcgccgagca aggcagccat cacaacgtcg cggcccgtca
    16501 tgagctttcc gtctgtttct aatacaacac ggtcacgaag tccgttcagc attagtgttt
    16561 gatgtgcttc tgcaaggcca agctcccacg gaagccctgt atgtttaata ctggttttcg
    16621 gagaagcgcc tgtacctccg tcatagccgc tgatcacaat gacatctgca gtcgctttgg
    16681 caacacctgc agcgattgtt cctacacctg cttttgacac cagctttacg ctgattcttg
    16741 cgtcacggtt ggcatttttc aaatcgtgga tcagctgggc taaatcctca atcgaataaa
    16801 tgtcatggtg tggcggaggt gagattaatc cgacacctgg cgttgacccg cggacatcgg
    16861 caacccatgg atataccttg ttgccaggaa gctgcccgcc ttcacccggc ttagcacctt
    16921 gagccatttt aatctgcagc tcatcagcat tgacgaggta atggcttttg acaccaaacc
    16981 gtccggatgc aatttgtttg atcgcacttc ttctatcatc gccgttctca tctggaacaa
    17041 agcgtttggg atcttctccg ccttcaccgc tgttgctttt tcctccaaga cggttcattg
    17101 cgattgctaa agcttcgtgc gcttccttac tcaaggaccc gaatgacatc gcacccgttt
    17161 taaaacgttt gacaatcgat tcagcggatt caacctcctc caacttcaaa ggcttgcggt
    17221 ttccgtcaaa tgcgaacaag ttccgcaaaa atccgatgcg ttcttcatca gccgcttttg
    17281 tatactgttt aaacagattg taatcatttc tgcggcacgc ccattgcaaa gtatgaatcg
    17341 ttttcggatt aaacgcatga tgctctccgc catttctcca ttggaagtca cttcccggtt
    17401 caagcgtttt gctgtaatca tcctgatacg cttcccggtg gcggcgctgt gcctcttctg
    17461 caattgtttg taaatcgatg ccgcctagct gtgatgcagt acctgtgaaa tagcggtcga
    17521 tcacatcgcg gctgattcct accgcctcaa agatttgtgc gcctctgtag ctttgcacag
    17581 ttgaaattcc catcttggac atcactttta cgacgccctc agtaatgctt tttccatatt
    17641 tgctaaccgc ttcttcatag ctgatatcca aacggccttc atcaatttcc tgcttgtagg
    17701 tcgcataagc gagataaggg ttaatcgcat ctgcgccata accgattaac gctgcaaagt
    17761 gatgcacttc acgtgcttct cccgattcca caataatgct gaccttcgta cgcagccctt
    17821 tgcggattaa gtgctggtgc agtgcgctta ctgccagaag cggcggaatt ggtgtcagtc
    17881 gttcgttcat ctttttgtct gataaaatta acaaacttac gccttggctg atggctttct
    17941 ctgcctgtgt gaacatgtcc tttaaaccgc gttcaagatc ctctgaaaac agcacatcaa
    18001 ttttttggct ttttaaatca ggatgaacaa tcgttttcaa tgcgtaaaac tgttcattgg
    18061 ataaaacagg tgtatacagt ttaatccggc gaacatttcg ttcacttgga tgaagaagat
    18121 cgccttccgc accgagccaa gtcatcgttg aagtgacaag ctgctcacga atcgcgtcga
    18181 ttggcgggtt cgttacttgt gcaaacagct gtttaaagta gttaaacagt gattgcgctc
    18241 ggtcagaaag tacagcaagc ggagcgtcat tccccattga accaagggga tctttgcctt
    18301 ctttaataac aggaattaga tacttttgga tatcctcata tgtgtatccg aatgccttct
    18361 ggcgagtaag aagatcacta aattgttctt cttctcttga ctccggatca ggatttactt
    18421 gtacaagctc ttcttcaagc catttttggt acggatactc agttgcaatt tgtgttttga
    18481 cttcttcatc ggagataata cggccttctt ccaggtcgat taaaagcatt ttcccaggct
    18541 caaggcggtt tttatataaa acgttctcct gttcaacttc aataacgcct acttcagatg
    18601 agaaaataat ataatcatct tttgtgacat aataacgggc cggacggaga ccgttccggt
    18661 caagtatcgc cccgatttgt ttaccgtcag taaatgaaat ggctgtcggt ccgtcccaag
    18721 gctccatcag ggagctatgg tactcgtaga acgccctttt ttccttggac atatgcgtat
    18781 tttccgtcca aggctctgga atgagcatca ttgccgtatg tgccggtttg cgtccagcca
    18841 tcacaaaaaa ctcaaatgcg ttatccaaaa tggaagagtc actgccatca gcattgagaa
    18901 tcggcaaaat cttgtttaag tcctcaccga agctttcaga aacaaattgc tgctcacgtg
    18961 ctctcatcca gttgatattt ccgcgaaggg tgttaatttc accgttgtga accaaatagc
    19021 ggttaggatg cgctctttcc catgtaggga atgtattggt actgaagcgt gaatgaacaa
    19081 gcgcaaaagc agaaacgaat gcttcgtctt gcagatcaga ataaaatgca tcaacctgtt
    19141 caggtgttaa aaggcctttg taaacaatgg tctggcttga aagactggca aaataaaaat
    19201 caagaccttc cgttactccc caattttcag cctgtttacg aatgacatac aattttcgtt
    19261 caaaagataa attgtccttt agatcagaac ttgcgccgat aaatacctga cggacaaacg
    19321 gacagctttt ttgcgccact gttccgattt ttccgacatt tacaggtaca gttctccatc
    19381 caagaacgac ttggccttct tgttcaatca gtgcattgat ttgcttttca attttttttc
    19441 tttcatcttc tttctgtgag aaaaagacca ttcctacccc gtaacgttct ttttctggca
    19501 gattgatgtc tttgcactct tttctaaaga aagcatcagg gatttgaacc agtaagccgg
    19561 ctccgtctcc tgtatccgga tcactgcctt gccctcctct atggtctagc tggcaaagca
    19621 tcttaagtcc ttgtttgaca atgtcgtgag tctgcttgcc ctttaagtgt gcatataggc
    19681 cgattccgca tgcatcatgt tcaaattcag gacggtagag accttgagct tttggcattt
    19741 gattgtacgt cataattcct ctcccccgat caatttccga taataccggt cataaaatct
    19801 aacaactcta taatcattgt aggttttcaa aacgatataa acaatatata atttagatca
    19861 aaagaatctc aaaatgagat agatggatgt gagacaaaca tggagctgcg ccaactgcgt
    19921 tattttatgg aggtggctga aagagaacac gtttcagaag ccgctgatca tttgcatgtg
    19981 gcccaatcag caatcagcag acaaattgcc aatcttgaag aagaattaaa tgtgacctta
    20041 tttgagcgtg aagggagaaa tatcaaactc acgccaatcg gaaaagaatt tttgattcat
    20101 gtgaaaacgg cgatgaaagc cattgattat gcgaaagagc aaattgatga gtatcttgac
    20161 ccgcatcgcg gaacggtaaa gatcggcttt cctacaagcc tcgccagcca gcttttgccg
    20221 actgtcattt cagcgtttaa agaagaatat ccgcacgtcg aatttttgct gcgccaaggc
    20281 tcctataagt ttctgattga agctgtcaga aaccgcgata ttgatctggc cttattaggg
    20341 ccggtgccga cgaatttctc tgacataacg ggaaaaatat tatttactga aaaaatttac
    20401 gcgcttgttc cattaaatca tccgcttgct aaacaaaaaa cggttcattt aatcgatttg
    20461 cgcaacgacc aatttgtatt gttcccggaa ggatttgtac ttagagagat ggcaatcgat
    20521 acttgcaaac aagcaggctt tgctcctctc gtttccacgg agggtgagga tttggatgcg
    20581 atcaaagggt tagtgtccgc aggaatgggc gttacccttc tgcctgaaag tacttttgct
    20641 gaaacaacac ctcgttttac tgtgaaaatt ccaattgagt tccctcaagt aaaacggact
    20701 gtcggaatca ttaaaccgaa aaatagagag cttgcgcctt ccgcgaatga tttttatgag
    20761 tttgtcattc aatttttctc taagctggag cagtatcaat aaaaaaaatg aacccgagct
    20821 tctatataga agcttcgggt ttttttctgc aaattaattt acaggtaaag aaaaatccac
    20881 atggcaaaca aatgcttctt gatcaattag agctctattt gtcagttcct ttttcttttc
    20941 cggttcttga agctgtacag aagagtaatt gacgattcca aggccgattt ccgtcccttt
    21001 tgaatccatc agccgaacaa ctgaaccgct tttgaatttc cctttaatct tctgtacacc
    21061 gtctaggtat aaactcgatt gtccgtttgt tatttttcgt gaacaatcat ctgataaaat
    21121 catttcacct tccggaccgg aattaaaagc gatccattgc tccttttgat tcaacggaag
    21181 cgttccttct gcttcaaaat aggtgccttc cgcctgttca tgaacggcgt ggtataaaat
    21241 atcgccagca tctgcctgac ctaggaaacc tttaatgcca gacgccatta cgattttaaa
    21301 cgcatcaagc ttagagcgca tgccgccggt gccaacgatg cttccagtgt cacctgcgca
    21361 tgcttcgatg tcaggtgtta tttcactcac ccgctgtatc cttttcgctt ctggatttgt
    21421 gcgcggattg ccgtcatata atccgtctat atctgataaa atcacaagca tatctgcatc
    21481 aatcaatcct gcgacttttg ctgcgagcgt atcattgtcg ccaaacttga gccgattgac
    21541 ggtaactgtg tcattttcgt ttatgatcgg gatgatgccg cgctcgagca gtacattcat
    21601 tgtattcctg acattgttgt atcgatattc atcagaaaaa tcgcttcttg taattaaaat
    21661 ttgggatgcg acatagccgt gtgccaaaaa cagctttgaa taagcctcca ttagcaatcc
    21721 ctggccgatt gaagctgatg cttgtttttc tggaagcttc tcgggccttt ggataaatcc
    21781 gagcttccga tatcccgccg ccactgcgcc tgaggaaacc aaaatcactt cataaccggc
    21841 gtctttgagt ttgacgacct ggtcgaccaa cgcttctaat tttcgaatgc tgatttctcc
    21901 atgaaggctt gttaatgaac tgcttccaat cttcacaacg actcttttca tgcttgtatc
    21961 aggcgtcact ttatcactcc tgatagcggc gctgcagttt tttcgatatc ttcgctgatt
    22021 tcctttgaac gcttagccgc atgctttatt gcttgagaaa tcgcttctcc gccgccgctc
    22081 tttttcaagg cttgcagccc cgctgctgtc gttccgttcg gtgacgtgat attatctctt
    22141 aagatctcag gatgttctcc tgtttccatg agcatttttg cggcacctaa aagtgtctgt
    22201 gcgccgatgc ttcgagataa ctgtttatcg aggcccgctt cctcgcctgt cttttcaatg
    22261 aattccatta aataataaaa atacgcgggt ccgctgcctg caattccggt gaatatatcc
    22321 atttgatttt cttggattgt atagacttcg cccatgcatc cgagcaatgc ttcggccagc
    22381 ttcttcaggt cttccgacac atatttgcca agggcaatag ctgttgcaga agcgccaatc
    22441 atactggaag tgttgggcat cactctgaca accggctgtt cattaagcaa tgattgttca
    22501 ataaaagagg tagttatgcc ggcaaggacc gacaatatta attgatgggg ttgaatacgt
    22561 gattttagtg atgacagagc gttttcggcg tcttttggct tcattgccaa aatgagcaca
    22621 tccatgtctt caatacatag ttggttcggc aaggcgcctt taatgccata ttgaagttca
    22681 agttcagtta atcgctctgt attgctgcgg tttgtaacgc agatgttttg tttcgggatt
    22741 ttgttggcac gaacgatacc tgatatcatt ccttccgcca tagatcctgc tcctataaag
    22801 gctactttct tttgatcaaa gatcggtaac atctcctttg ttcgcttttt tgttcgcatt
    22861 ttcacacgtt taaaatgtta ccacgtgagg aaatgatgtc aagtttgaag gtcatcattg
    22921 atttgtattg tttcttttcg acaaatatgt ataatgaaaa gcagaaaaca cccggttcac
    22981 actgctgcgc cgggtgtttg tttctattaa aaat
//
