LOCUS       NZ_LT732548            22385 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Paenibacillus bouchesdurhonensis strain Marseille-P3071T, whole
            genome shotgun sequence.
ACCESSION   NZ_LT732548
VERSION     NZ_LT732548.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus bouchesdurhonensis
  ORGANISM  Paenibacillus bouchesdurhonensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1
  CONSRTM   Urmite Genomes
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2017) URMITE, 27 Bd J Moulin, 13385 Marseille
            Cedex 05, France, 13385, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900155685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:11:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,206
            CDSs (total)                      :: 5,108
            Genes (coding)                    :: 5,019
            CDSs (with protein)               :: 5,019
            Genes (RNA)                       :: 98
            rRNAs                             :: 8, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 3, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 31 of 89
            Pseudo Genes (incomplete)         :: 75 of 89
            Pseudo Genes (internal stop)      :: 9 of 89
            Pseudo Genes (multiple problems)  :: 21 of 89
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:18:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4410045
            Orig. end                         :: 4432430
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT732548.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22385
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22385
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22385
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12385](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12385
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    402..414
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    1810..1825
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(1826..2152)
                     /locus_tag="CZ379_RS24160"
     CDS             complement(1826..2152)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426384.1"
                     /locus_tag="CZ379_RS24160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="WP_110933947.1"
                     /transl_table=11
                     /translation="MPVYNKLVRDKIPQIIAADGKAYRSRILDKEEYLQELRTKLREET
                     EEYFNAANDKEALEELADMLEVIRALAEAHGSSPTVLEKIRVDKAEKRGGFQDRVYLID
                     VDEA"
     gene            complement(2258..2686)
                     /locus_tag="CZ379_RS24165"
     CDS             complement(2258..2686)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS24165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_110933948.1"
                     /transl_table=11
                     /translation="MVSEMSVEHNKHTHPQTYMNLTTMFLNHCLPKPCFILCDLALESM
                     LKAIYVQERESILSPFILTFEDLLDLFRYESDVDLEALCLIQSIKFLANSTSSNNVVLK
                     CSKPHLQMLIRKVDELLCKLSPRAISSTTEMYNSIFKE"
     gene            2855..3202
                     /locus_tag="CZ379_RS24170"
     CDS             2855..3202
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492980.1"
                     /locus_tag="CZ379_RS24170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_110933949.1"
                     /transl_table=11
                     /translation="MNDKEILKLVGARVKTLRKQQGYSQESLGEKGGFHFSYIGQVERG
                     EKNISLLNLSKIAKALDVNVAQLFTYVHEHSELTEEDVEVKEIVMMLRGSNPEKLRLAK
                     NVLREIVRGIE"
     gene            complement(3291..5252)
                     /locus_tag="CZ379_RS24175"
     CDS             complement(3291..5252)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012958836.1"
                     /locus_tag="CZ379_RS24175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2075 domain-containing protein"
                     /protein_id="WP_110933950.1"
                     /transl_table=11
                     /translation="MIIYEATKEEFMNDVTDDSIAVKIHESYLQKIGKVSLGEINSWNN
                     SMNYMYKVLNTPIIPDDVGVAIEYKVPTTSRRIDFMLTGLDEKDRYSVVIVELKQWSAL
                     NKVESLDGLVETVINKRLGKHTHPSYQAYTYAKLISDYNESVQNELISLYPCAYLHNYI
                     REDDDPLTDDIYENWISEAPVFTKGDALKLRGFISTYIKKSDRKKSLYLIEHGKIKPSK
                     SLQDSLLKMLEGNEEFLMIDEQKVAYEVAILMAKKAQTTDRKQVLIVEGGPGTGKSVLA
                     INLLVQLTAQEMVCQYVTKNSAPREVYTKRLQRGYKKTVINNLFKSSGVYYEALPNEFD
                     ALIVDEAHRLNEKSGLFKNKGENQMMEIIRAAKCSIFFIDEYQKVSMQDVGNKEQIKQF
                     AKLYDAEVVEIELESQFRCNGSDGYLAWLDDMLAIRETANSDGFDIQYDFRVFDDPNEL
                     RNEIFKKNHNNKARMLAGYCWDWIRDGKSNPEVHDIYLEEHQFSASWNLNNTQTWAIDP
                     ESVEQVGCIHTSQGLEFDYVGVIIGEDLRYMDGKVVTDPFKRAKTDKSLSGFKSLYKKD
                     KNKALRIADQIIKNTYRTLLTRGMKGCYIYCVDPLLREYFLERLSSQKSITYPLYEERE
                     YAVAEERTSYVTGEKLRK"
     gene            complement(5268..5600)
                     /locus_tag="CZ379_RS24180"
     CDS             complement(5268..5600)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007543182.1"
                     /locus_tag="CZ379_RS24180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="WP_110933951.1"
                     /transl_table=11
                     /translation="MDDVINKIIKFRDARDWKQFHNPKDLAISLTLEASELLENFQWKS
                     SDQAVDTNFDDIRDELADVLIYSLMLAHDLGIDVKGAILDKLEKNDKKYPIEKFKGTSK
                     KYTEAE"
     gene            complement(5804..7063)
                     /gene="tyrS"
                     /locus_tag="CZ379_RS24185"
     CDS             complement(5804..7063)
                     /EC_number="6.1.1.1"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tyrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019637037.1"
                     /locus_tag="CZ379_RS24185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine--tRNA ligase"
                     /protein_id="WP_110934546.1"
                     /transl_table=11
                     /translation="MNIIDELEWREAINQQTDAEGLRKLTEEKAISLYCGVDPTGDSMH
                     IGHLIPFIMLKRFQLAGHKPVILIGGATGTIGDPSGRQSERSLQTLEQVQANVEALTAQ
                     MKKLFMTDGDNQLRLVNNYDWTHQLNVIDFLRDYGKNFSINAMLAKDIVASRLDTGISF
                     TEFSYQILQSMDYLHLYQEEDVQLQIGGSDQWGNITSGLDLIRRKVGPEAKAFGLTIPL
                     MLKADGTKFGKTAGGAIWLDPKKTTPYEFYQFWANTDDRDVIKYLKYFTFLDKEAIDAL
                     AEKVQTEPHKREAQITLAEEMTRFVHSEEALAQAKRITAALFSGDIKSLTADEIEQGFK
                     EMPTFEAAKESKNIVDWLVDVGIEPSKRQAREDLTSGAISLNGERVNELEFEITVDLAI
                     EGRFIIVRKGKKKYHLVKLV"
     gene            complement(7409..7705)
                     /locus_tag="CZ379_RS26875"
     CDS             complement(7409..7705)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS26875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_234405005.1"
                     /transl_table=11
                     /translation="MKSILKDEWIIQNAAEAEVGRIKEDSRLFAFLRRFLSDLIPQTYN
                     VEMNGSTVTFKQNFNPFVTKIDVDFSSDPSHMLDRRLGLAASVLLCAIDGKQS"
     gene            complement(7724..7981)
                     /locus_tag="CZ379_RS26880"
     CDS             complement(7724..7981)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS26880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_234405006.1"
                     /transl_table=11
                     /translation="MDHFGYDQYLVRKKILSLLGAQFHIYNANEELVMFSQMKAFKLKE
                     DIRLYNDEGMSQELLTIKARNVIDFSATYDVHDALTGEHV"
     gene            complement(8368..8898)
                     /locus_tag="CZ379_RS24195"
     CDS             complement(8368..8898)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018184.5"
                     /locus_tag="CZ379_RS24195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GyrI-like domain-containing protein"
                     /protein_id="WP_110933952.1"
                     /transl_table=11
                     /translation="MNYEIVYVEEKTVVGLRIRTSNSDPYMSRSIGELWQRFYQEGIYD
                     SIPGKHNDKSIGLYTDYQMGDNDAYDVIVCCEVEGSVEAEVKEEVKAETDAGTEVGRGA
                     GADAELELEEKTIPAGKYAKFIVRGHVQQAVAEFWTKLWSMELDRKFSSDFEEYQSGGN
                     MDNAEIHIYIALN"
     gene            complement(8982..9884)
                     /locus_tag="CZ379_RS24200"
     CDS             complement(8982..9884)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018757442.1"
                     /locus_tag="CZ379_RS24200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YafY family protein"
                     /protein_id="WP_110933953.1"
                     /transl_table=11
                     /translation="MQINRLLEIVYILLDKKQVTAKQLAEQFEVSQRTIYRDIDTLSAA
                     GIPVYTNKGKGGGIRLLDQFVLGKSMLSDKEQMDILSSLQGLNALNVPDVEPVLNKLAA
                     IFNKNATSWIDVDFSRWGSDSTEQKKFNLLKTAILNRNVVNFDYYSSYGEKTERIVEPV
                     KLIFKGQNWYIYGFCRLKNDFRMFKVTRIKNPTCSEETFIREMPMDIWNDPPDFNRRVV
                     KLVLKIEASMAYRVYDEFDQNGITKNPDGSFVVKVSYIEDEWVYGYILSFGNNAEVIEP
                     EHVRDIIQRKLEASLRKYL"
     gene            10001..12385
                     /locus_tag="CZ379_RS24205"
     CDS             10001..12385
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007130291.1"
                     /locus_tag="CZ379_RS24205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_110933954.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.9e-43, bitscore:
                     144.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDDITVQQADTWYQKAEQKAVQYLTSLQQRVRDQTDLQTLTADI
                     QLWKKNHVHHFWRSLLPHRNKTPDALGYRKYIGWLNRTGKLDNYLDRSISYIYMRDLGK
                     ALDSPEAQARIKRTMSDVKKLLLRSTGTGQGEQPEFMNLAGLYRWAQKENIEDAIIWLI
                     GKLNHVSSQIPEGMDAEHAQRKLMKIIIGVVLHVMDEMDDRILPDERSRRLDEAIRLGY
                     SYGLTYPFIDDLLDSEILNDKEKGQYSQMIRSALLTGSVPESGEWNGEHSDFIHYAYAE
                     LREAFEYIKSYQRPEAISTFFEQSYVFFHAQDLDRVKELSHSAYTNEELYLPVILKSSS
                     SRLIVRSVISAPEDEGFEQRTFYYGIYNQLADDFADMFEDMRTGAVTPYTYYLKYRRLR
                     PDLINPYELYWTVISYLIHSVYHSDAKAREIILNRAINGLKRCKKRLGVDKYTEVMDIF
                     ASGNPEFNRLVQRMVQQADDVDFLDKLLRDQVVTVLRNSRNDKESFIDTLQSVRDQLNE
                     QLQIRKSDGIPLVTESLIETANYSLRGDGKRLRPILTWAMGVNEYGLEASAIMPLLKSL
                     EYMHTASLIFDDLPSQDNASTRRGRPTLHQVHDSATAELTGLYLIQKAVEEQTSLSGFD
                     AESVLALIRYSSQKAGEICLGQAMDLESRGKALTLEQLNTICFYKTGIAFEACLVMPAI
                     LAQAAEKEVASLQKYAYHAGIAFQIKDDLLDSEGETSLLGKPVRQDVENNNSTFVTLLG
                     HEGARRAMWEHYCQAMETLNELPRSNVFLKHLLNYMVSREK"
     gene            complement(12526..13473)
                     /locus_tag="CZ379_RS24210"
     CDS             complement(12526..13473)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017246911.1"
                     /locus_tag="CZ379_RS24210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DMT family transporter"
                     /protein_id="WP_110934547.1"
                     /transl_table=11
                     /translation="MKYLLSVLIGASSYGVLSTIVVLAYGQGYQLGEVVGTQLLTGCIL
                     AWLLAIYTGWKERRKEEKSVNALTKASSNRSARLSWKHRFLLMLAGTPTAITGLLYYHS
                     LRYIPASLAIVLLFQFTWISVLVQAVSKRQRPNGITLITLGLLLGGTLFAAGLMEQRDG
                     NFPMIGIALGLLSAVSYTLFILFSGKALPAIHPAYRSAWMITGGLVLVFILFPPQFLFN
                     GMLWSQLLLFGFLLGLFGAFIPPVLFAVGVPHIGEGMAGILGAAELPVAVLLSSFVLHE
                     QVTPLQWGGVIIVLLGVMLPELHKRRARTVEYSS"
     regulatory      complement(13554..13666)
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(13746..15917)
                     /locus_tag="CZ379_RS24215"
     CDS             complement(13746..15917)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019113.5"
                     /locus_tag="CZ379_RS24215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 105 protein"
                     /protein_id="WP_199925756.1"
                     /transl_table=11
                     /translation="MLKQHENSIYDKTGTDIKAALRSLANRYVADHPAEPFSYRAFNRE
                     GIQRANDFRYVFDLAERFPEAEVGQVSYAWSMVWSDEPETEMTWLATAWGPMEVFVNGR
                     SIYRSQPQEERPKVNRECRSILRAGWNDIVLKFTKTRAGFGGHFGTTSSKWVIFNAIVA
                     SKERSGQEGWLFSKPLARAVAELPRAGQTEFDGILEWCPRPDWTKEQYLLTPMERLFGA
                     AKGQSAFAWTQFHANGVEAQAYRITGHSFGPTTIWIDGTAIYHSEQAGEFGVTVELSFG
                     PHQLMIRDTLGPSWGTKVTVGLGDEVVPFMPPVAVQGYLGAWLFLGPFAEECIPDLGDL
                     TDLSRVHADGGEGTYWRVDLPGTWIRPYLEAPLFGKWNYPVGVTLYGLVETGRELSRPD
                     LVAYAAAHVAQTVKWYPYTQWDYKQYKATGINQSIADIDSLDDCGSFGSTMLEVYRDNL
                     EMTGVESLACEIGNYIRDVQERLPDGAFYRKHFQDEHTMWADDLYMSVPFLCRYYRLTG
                     DEQYIDDAARQFLLFRKYLFIPEEKLMSHVYDFEQGLATGVPWGRGNGWVLFSLSELLT
                     VLPKQHPHREQLLEMFRTLSAGYLVHQSEEGLWRQVINEPDAYLETSCTAMFIYAYARG
                     IRNGWLTNRTAYTNSAVRAWEGLTRHSIDAKGNLHGVCRGSGYSHSSHYYKHDLLPQLN
                     DTHGIGIVMLAGIELLRLTEWLREFKPSM"
     gene            complement(16111..17550)
                     /gene="pyk"
                     /locus_tag="CZ379_RS24220"
     CDS             complement(16111..17550)
                     /EC_number="2.7.1.40"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030955 - potassium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pyk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009594353.1"
                     /locus_tag="CZ379_RS24220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyruvate kinase"
                     /protein_id="WP_110933956.1"
                     /transl_table=11
                     /translation="MLRTKIICTLGPACDTVEILKEMIKAGMTVGRLNMAHGEPEEHAE
                     RISRLREAAKEVDAYIPVMMDIKGPEVRIGKLKEASSQLKAGEELILTTENIEGDSRRI
                     SVNYAEMPAVVKKNDRILIDDGLIELDVIEVEGTEIRCHIKSGGTLKPRKGVNLPGIRT
                     TLPGVTERDIRHIDFGLEQGIEMIAVSFVRKGDDIREVRRLLEERGAGHVQIISKIEND
                     EGVRELDDIIEASDGIMVARGDLGVEVPVENVPAMQKEMIDKCNLAGKPVIVATHMLES
                     MQVNPRPTRAEVSDVYNAVIQGADVVMLSGESAAGKYPIPSVQTMARVAQQAESTIDYR
                     EQFNRKRVQHVTNITEVISQGVVSASLELEAKAIITSTESGFTARMVSKYRPKAPILAI
                     THDRHVLSAICLLSGVFPFQGEQVSTTDEMFDKAIRRALKTGYVGLGDTVVLSAGLPLG
                     QAGTTNLIQIQQVEARGIFIS"
     gene            17760..18314
                     /locus_tag="CZ379_RS24225"
     CDS             17760..18314
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019637046.1"
                     /locus_tag="CZ379_RS24225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_110933957.1"
                     /transl_table=11
                     /translation="MNAVRYVKKAKRGNKDALLQLILAEKDSYYRLALTYMGNSHDAMD
                     AMEEMIVKLYENIGQLNKEEAFYSWSKTILANCCKALLRKRDKLVLIDDVSRDGDLAAD
                     YDPQFGDPYRRSDQQIDIQKLLLHLNEQQQEAIQLKYWHDFDYQTIAEITNVPIGTVKS
                     RIFQGLKKLRELYGEDMYESR"
     gene            18301..19596
                     /locus_tag="CZ379_RS24230"
     CDS             18301..19596
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018708688.1"
                     /locus_tag="CZ379_RS24230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4179 domain-containing protein"
                     /protein_id="WP_110933958.1"
                     /transl_table=11
                     /translation="MNHVEKRLAEEKMRIDSVTAPEELETRLRDALNKTDSQRTKRRIP
                     SVWKAAAVALFFLVVFGYHYNAFAYYGKKLLGFDELIGGSQLQELNEQGMGQIVDKKTN
                     LSDGTELTINGIMTDANQLIMYYTLTNPEGIEDNGIDLFRPSKFTGFLTNSNLESGTSL
                     QNEEQTEVKGTMSFQPVSPFAKKLNLHYWDRTENNQLIEHTISFPYDPNQAMQTEVRKS
                     LRKTVKVDKGTLNFQSITATPTMTMIEGSLNVDNFDRLPSALSGIELIANGTPVELIGS
                     GHGSSLGGRKFDLRYGALPKPLTSLELVMKEFVGYQQLDQRLPLSSAGNEPFSLDGKKL
                     WVKKAAVTSQGVEITIATDDDILLDGVSIETQNETTALKTTVNQIETKLDDGGILKERT
                     LLFDTSVMPEYLHIKGIHYMKAYNKVIEIPVK"
     gene            complement(19790..20830)
                     /locus_tag="CZ379_RS24235"
     CDS             complement(19790..20830)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006039458.1"
                     /locus_tag="CZ379_RS24235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_110933959.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.9e-21, bitscore:
                     75.0, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 8.5e-15,
                     bitscore: 52.8, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQHRIVVAGCGEMSNVWIKELLKRDDAVIVGLVDVYIGQAEKV
                     RDAYGLECGVYTGLEQAIVDTGADLVIDVTIPDSHYEISTTAMKHGCHVFGEKPMAATM
                     REARKIIETADATGRSLSVMQNRRYDVNIRGLRELISSGTIGRLGMINADFFLGPHFGG
                     FRDVMESPLILDMAIHTFDQARFIVGADPVSVYCHEFNPPGSWYKGNASAVCIYEMSDG
                     SVFSYRGSWCAEGVPTSWEGDWRIVGEKGTAIWDGIHAPYAEVLASELAADDAAEKKFI
                     RDMVRIEVPLNWSGKPGHEGCLDEMFQALKEGRPAETDSRDNIHSMAMVLGAIESAKSG
                     RKVMLG"
     gene            complement(20935..21831)
                     /locus_tag="CZ379_RS24240"
     CDS             complement(20935..21831)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019637049.1"
                     /locus_tag="CZ379_RS24240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_110933960.1"
                     /transl_table=11
                     /translation="MQHGNHLLRIGTLVGGQDAVRVIPQILPHGFESFSLTFWQTTGGI
                     DLAELAKQVRKMTDEHGVVISSIGVFGNPLTGEGDNADTLASWERAIDHAHLFGADIVS
                     GFTGRLTDRPIDESLPRFKEVFGELAKRAADRGVRIAFENCDMGGTWWKGDWNIAHNPQ
                     AWEMMFNEVPADNLGLEWEPCHQMVSLIDPIPQLRKWVDKVFHVHGKDATIAWDIVKEY
                     GIHGPKEFVWHRTPGFGDTNWTDIITILRQAGYKGTIDIEGWHDPVYRDELEMTGQVHA
                     LNYLKQCRGGAFVPNPL"
ORIGIN
        1 gtcgtacagc agcttctctc gatgcggaag tctttttcga ctcaactcat tcagaagatt
       61 aatcacttgc gtatcaagcg taatttcaca acccgctggc acacttggca cgacttcctt
      121 ggacttactc cgtgcgccgt tcacatcatc ttctgcaaaa agccgcagct tcacgtctgc
      181 atttcgatag ttaccgatca aatcaataat aacgcaatgc gtctttccct ctgatagccg
      241 gagtccccgt cccacttgtt gcgtgaacac ggtcaatgat tctgttggac ggacaaacaa
      301 caaagtatct acacttggaa tatccgtccc ctcattgaac agatccacag taaaaataac
      361 ctcaagccgc cccgccgaaa gacgactaat agcttcagca cgtgacattt tcactgtacg
      421 tgagtgtagg ctcaataccg aaattccacg cctgtggaat gcatcagcca aataatcagc
      481 ctgccgaata gacgaacaga acgcaatcgt cctagtttgt ttattcttca tccatgcctc
      541 ataaatccgc tcggcctgtg actcctgaag ctgtgttgat aataattgtt cttcatcata
      601 acgcgtacct agccagcgaa tagccgaata atccgtatca tcgaacacgc cataatattg
      661 aaagggagct agccactgcc gccgtatcgc ctcaataaaa tgcatctggt aagccacgtt
      721 cccatcacaa agcgcataca catctttgcc atccatccga tctggtgtcg ctgtaatccc
      781 caataagaac ttgggttgaa aatattcaat caccgacaaa taagaagctg atgccgcatg
      841 atggaactcg tccacaataa taaggtcgaa agcatctcgt gtaaaggact cacggtgctt
      901 ccgcattccc agcgtaaaaa ttgaggcgaa tacacaatcc gcttctcctt ctttgtaatg
      961 cccgttgaaa attccaaatg aacgttcagg catgacccgc tgaaaggatt gacgtgcctg
     1021 atgcaatatt tcctcacgat gggcaataaa tagtatctta gagaaacgct cagcaaaaaa
     1081 gccagccaaa taagttttgc caagtcctgt tgccataacg accactgcct tgtcgtattc
     1141 ttcctccaat gttcgctcga gggcttccaa cgcttcctcc tgggcaaagc gtggacgaat
     1201 tgactcagtt tcctgtgttt cttcatccaa tcgaggctca gtacttaagc ccaaatcagc
     1261 ttcagatttc tccatctccg taatacgtcg tatcagctcc ggattcctct gatgatactg
     1321 gagatactcc tcttcataca tgtggatcga atcagggttt atcggaagcg tggtctcatg
     1381 gtagaaactt tccataaact tatctaatgc catttggaac gtataaggct cggcctgagc
     1441 attcatagcc aggttccatt catatcctgt acgaagcgct gaaaatgaga aattcgacga
     1501 acctacaata agcagacctt cgccttcatc ataatcaaac aaatatgctt taggatgaaa
     1561 tgaggagccc atactccgcc acaatctcgc ctcaatccgt tcatcaatgc caatcaattc
     1621 aagcaatccc tctggctgag tgatatacaa ataatcccct gccagcattt taacttccgc
     1681 tccccgatcc aaggcatttt ttatatgcgg agccaacagc catacaccgg actgcatgag
     1741 aaatgacgtc ataatatata tcccagaagc gctttgaatg ccagcaatca gctcatctgc
     1801 caaattatcg gtgatgagct tcacattaag cttcgtcgac atcgatcaag tacaccctgt
     1861 cttgaaatcc gccccgtttc tcggccttat ccacccggat tttctccaat actgttgggc
     1921 tagatccgtg agcttccgcc aatgcccgga ttacttccag catatctgca agctcttcca
     1981 gagcctcttt atcattagca gcattaaaat attcttccgt ttcttcacgc agcttagttc
     2041 gcagctcttg caaatactcc tccttatcca gaatccgtga tcgatatgcc tttccatcag
     2101 cggcaataat ctgtggaatt ttgtcccgaa ctaatttgtt atatacaggc ataaatagca
     2161 ctccttctct tcttctttag agaattatat atgccgtcat tatatcattt tctggtagag
     2221 aagaaccgtt catggcgtta tttctaggct tagaaagcta ttctttaaaa atagagttgt
     2281 acatttctgt agttgagcta atagccctag gagatagttt gcataatagt tcatccacct
     2341 ttcggataag catttgcaag tgaggcttgc tgcatttcaa tactacgtta ttagaacttg
     2401 ttgagttcgc aagaaactta atagactgaa ttaagcatag agcctctaaa tcaacatcag
     2461 attcatagcg aaagagatca agcaggtctt caaatgttaa gatgaatggc gacaagatgc
     2521 tttcgcgctc ctgaacgtat atcgctttga gcatgctttc tagggccaag tcgcagagaa
     2581 taaagcaagg cttgggaaga caatgattca agaacattgt ggtgaggttc atgtaggttt
     2641 gaggatgagt gtgtttatta tgctctacag acatttcact aaccatacaa tactaacctc
     2701 cataaggttt ctcaaacacc aatattatac acatatataa tatctataga tattattttt
     2761 gatatatata agtattaacc ttatatttaa tacttatatg atgatgtttg tattaagata
     2821 tcttgtctac acttttgaat aaagaggtgt agatatgaac gataaggaaa ttctcaaatt
     2881 agttggtgca agagtaaaaa ctttaaggaa gcagcaaggc tactcccaag aatcactagg
     2941 agaaaaaggt ggttttcatt tttcttatat cgggcaggtt gaacgtggag aaaagaatat
     3001 ttcgttatta aacctctcca aaatagctaa agcgttagat gtcaatgtcg ctcaattatt
     3061 tacatatgtt catgaacata gtgaacttac cgaggaagat gttgaagtga aggaaatcgt
     3121 aatgatgctt agaggatcaa atccggagaa gctgcgtcta gcgaagaatg tgttgagaga
     3181 gattgtgcgg ggaatagagt agcgtaaata atgaaaaaaa tcgccgtgct tagtgcatcg
     3241 acgattcttt atgattaaac taaattaaat aaaataatta ataaactaat ctactttctc
     3301 aacttttctc cggttacata agaagtcctt tcctcagcca cggcatattc tctttcctca
     3361 tataacggat atgtaatact cttttgactt gaaagccttt caagaaagta ctccctcaac
     3421 aacggatcaa cacagtatat atagcagccc ttcatccctc ttgtaaggag tgtacggtaa
     3481 gtatttttta taatttgatc cgctattcgc agggccttat ttttgtcctt tttatataag
     3541 cttttaaatc ccgataagga tttatccgtt ttggcgcgtt taaatggatc cgtcacaact
     3601 tttccatcca tatatcgaag gtcttcgccg ataataactc ctacataatc aaactccagc
     3661 ccttgcgaag tgtgaataca gccgacttgc tccactgatt cagggtcaat tgcccatgtt
     3721 tgagtattat tcaaattcca gctggcagaa aactggtgtt cctccaagta aatatcatga
     3781 acctctggat tactttttcc atctcttatc caatcccaac aataacctgc tagcatcctg
     3841 gctttattat tgtgattctt tttaaaaatc tcattacgta attcattagg atcatcaaaa
     3901 actctaaaat catattgaat atcaaatccg tctgagtttg ccgtttctcg aattgctagc
     3961 atatcatcca accaagccaa gtatccatcc gaaccattac aacgaaattg cgattcgagt
     4021 tctatttcta cgacctctgc atcgtagagt tttgcaaatt gtttaatttg ttctttattc
     4081 ccaacgtcct gcatagaaac tttttgatac tcatcaataa aaaatattga gcatttagca
     4141 gctcggatga tctccatcat ctgattttca cctttgtttt taaataagcc tgacttctca
     4201 tttagtcggt gagcctcatc cacgatcaga gcatcaaatt cattgggcaa tgcttcataa
     4261 tagactcctg agcttttaaa taaattatta atgacagttt tcttataacc tctctgaagc
     4321 cgcttagtat atacctctct aggagcgcta ttcttggtta catattgaca gaccatctcc
     4381 tgtgcggtta attgaactaa caaattaatg gccagtaccg atttccctgt accaggccct
     4441 ccctccacaa tcaagacctg cttgcgatca gtagtttgag ccttttttgc cattagaata
     4501 gccacctcat aggcaacctt ctgctcatca atcattaaaa actcctcatt gccctctaac
     4561 atcttaagaa gtgaatcctg taatgattta gacggtttta ttttcccatg ttcaatcaga
     4621 tatagagact tttttcgatc ggatttttta atgtaagtag aaataaatcc cctcagcttc
     4681 aatgcatcgc ccttggtaaa gaccggggcc tccgatatcc aattttcata tatatcatcc
     4741 gtaaggggat catcatcctc cctgatatag ttatgcaaat aagcgcaggg ataaagagat
     4801 atcaattcat tttgaacaga ttcattatag tccgatatta acttcgcata tgtataagct
     4861 tggtatgatg ggtgtgtatg cttgcctaat cttttattta taaccgtctc aacaagccca
     4921 tctaggctct caactttatt cagggcggac cattgcttta attctacaat gacaacggaa
     4981 tatcgatcct tctcatccaa ccccgttaac ataaagtcta tccttctaga ggttgtgggc
     5041 accttatact caatagcaac gccaacatca tcaggaatga tcggagtgtt cagaacctta
     5101 tacatataat tcatagaatt attccaggag ttaatctcac cgagcgaaac cttaccaatt
     5161 ttctgcaaat aggactcgtg aattttgacg gctatactat cgtcagtaac atcattcatg
     5221 aactcttcct tggtagcttc gtaaataatc aaagatgtct caccccgtta ttctgcttct
     5281 gtatactttt tggatgtccc cttgaacttt tctataggat actttttatc attcttttct
     5341 agtttgtcta aaatagcacc tttgacatca atacccaagt catgtgcaag catcagtgaa
     5401 tagatcaata catccgccaa ctcatctcga atatcgtcaa agttagtatc gaccgcttga
     5461 tcactactct tccattgaaa gttttcaagc aattcacttg cttctaatgt taaagaaatc
     5521 gccaaatcct tagggttatg gaactgcttc cagtccctcg cgtcccgaaa tttaatgatt
     5581 ttatttataa catcatccat gtaagcactc cttggtagta gattatgagt ctattatagg
     5641 ctttatattt aaatagacaa atatggatgc ataggattgt agaaaacatt tttaattggt
     5701 cggatcaata accgctgtca tgaacaaaaa aatttcaaac aaaaaacaca gcaccctccc
     5761 gcaggaaaat gctgtgcctt acctttctta ctctaagcta accctaaacc aacttcacca
     5821 aatgatactt tttcttccct ttgcggacga tgatgaagcg gccttcgatc gccagatcga
     5881 ccgtgatctc gaactccagc tcatttactc gctcgccgtt cagggagatt gcgccgctgg
     5941 taagatcctc gcgtgcttgg cgttttgaag gttcgatacc tacgtcaacg agccaatcga
     6001 cgatgttctt ggattcttta gctgcttcga aggtcggcat ttctttgaag ccttgttcga
     6061 tttcatcggc agtcaaagac ttaatatccc cgctgaacag agctgctgtg attctcttgg
     6121 cttgagccaa ggcttcctcg ctgtgcacga atcgggtcat ttcttcggcc agcgtaattt
     6181 gcgcctcgcg cttatgcggc tcggtctgta ccttctcggc cagcgcgtcg atcgcctcct
     6241 tatccaggaa cgtgaagtat ttcaggtact tgatgacatc gcggtcatcg gtattcgccc
     6301 agaattggta gaactcgtat ggcgtcgttt tcttcggatc gagccaaatc gcgccgccag
     6361 ccgtcttacc aaacttcgta ccgtcggcct tcagcataag cggaatcgtt aagccaaacg
     6421 ctttggcttc cgggcctact tttctgcgga tgagatccag cccgcttgta atgttccccc
     6481 attgatcgga accgccaatt tgcagctgca catcctcttc ctgatataga tgcaggtaat
     6541 ccatcgactg cagaatttga tacgagaatt ccgtgaacga aatcccggta tccaagcggc
     6601 ttgctacaat atctttggcc agcatcgcgt tgatgctgaa attcttccca taatcccgca
     6661 gaaaatctat tacgttcaat tgatgcgtcc aatcgtagtt gttcaccagc cgcagttgat
     6721 tgtccccgtc agtcatgaac agcttcttca tttgcgcggt taacgcttct acgttagcct
     6781 gaacttgctc cagcgtctgc agactgcgct cggattgacg cccgctaggg tcgccgatcg
     6841 ttccggtcgc accgccgatg agaatgacag gcttatgccc tgccaactga aatcttttca
     6901 gcatgataaa aggaatcaaa tgcccgatat gcatgctgtc acccgtcggg tcaaccccac
     6961 agtacaagga aattgccttc tcctcggtca gcttgcggag tccctccgca tccgtctgtt
     7021 gattaatggc ctcgcgccat tccaattcat caataatatt caacctgttc agctccctat
     7081 attccataaa ataaaaaatc gtcccctagt ctatatcaga ctacagggac gattgaatta
     7141 accgtgttac cacccaaatt gtacgatgat actaaagccg gccggcttca tcataccact
     7201 ctcagctcat tatcgtgagc caacccgctt ggcattaccc aagatactcc ggagtgtaat
     7261 tcgcaaggga tcagtaatgc tgccaggttc catcaacccc tggctttctg gtaagcagtg
     7321 actgcccgct acttcgttcc ttcatcgtaa ttgacatata agtttacaga aagtatagtg
     7381 aattgatttt caattgtcaa atggtttgtt aagactgctt gccgtcaatc gcacataaca
     7441 atacgcttgc agcaagtcca aggcggcgat caagcatatg agacgggtcg ctggagaaat
     7501 ccacatcgat tttcgtgaca aaaggattga aattttgctt aaaagtaacc gtgctgccgt
     7561 tcatttctac gttataagtc tgcgggatca agtcgctaag gaaccggcgc aggaacgcaa
     7621 aaagccggct atcctcctta atccgcccga cttcagcctc ggcagcattt tgaatgatcc
     7681 actcatcctt caatatggat ttcatgcctt ttctccgcag gcttcagaca tgctcacccg
     7741 taagcgcatc atgaacatcg taggttgcag agaagtcaat cacattacgc gccttgatcg
     7801 tcaataattc ctggctcatg ccctcgtcat tgtacagccg aatatcctcc ttgagcttaa
     7861 aggccttcat ttgcgagaac ataaccagct cttcattggc gttataaatg tgaaattggg
     7921 ctcccagtaa ggagagtatc ttttttctta ctaaatattg gtcgtaaccg aaatgatcca
     7981 ctttgcccga tggcctccca tgaattttat tattttttat aatacggcaa gctgggggca
     8041 ttgtatatag cgtcttcctt ttaattcggg agtgtaagat caaatttcgt tcttcactgg
     8101 tggacttttt cacctgattg tttttcaaat ggtggacacc acatatatat ctgcaccgcc
     8161 catgaatatc tacatttaga agcttataag gatgcacaac actatatgca gttcattgca
     8221 agcgtggata agagcctctt tagtgtccac atttggatgg acatttattg catttcgtcc
     8281 acgacaggca tacaacaact atacagccat gaaccattca taatgaacat gttcccatca
     8341 cgcagcatcg aagccataaa cgcagagtta attcaacgca atgtaaatgt ggatttcggc
     8401 attgtccata tttccgccac tttggtattc ttcaaaatca ctgctgaatt ttctatccag
     8461 ctccatcgac cacagcttcg tccaaaattc agccactgcc tgctgtacat gacctcgcac
     8521 aataaatttg gcatatttcc ccgctggaat cgtcttttcc tctaactcta actctgcatc
     8581 tgctcctgca cctcttccca cctctgttcc tgcatctgtt tctgctttta cttcttcttt
     8641 tacctctgcc tccactgagc cttcaacctc acagcaaact atcacatcat atgcgtcgtt
     8701 atcccccatc tgatagtcgg tgtacaagcc aatgctttta tcattatgtt tgccaggtat
     8761 ggaatcataa atgccttcct gataaaaccg ctgccaaagc tcgcctatgc ttcgactcat
     8821 ataaggatca ctgttgctgg ttctgatccg caatcccacg actgtttttt cttctacata
     8881 cactatttca taattcatat accctacctc ttttcatttg atatcgaggt cagtatagca
     8941 atactaatta gacaacagca tgtcatatta tacgagcaag cttataaata ttttcgtaaa
     9001 ctcgcttcca gctttctctg tataatatcc cgaacatgtt cgggctctat gacctctgcg
     9061 ttattcccaa aggacaatat gtacccatac acccattcat cctcaatgta actaacctta
     9121 acgacaaagc tgccatctgg atttttagtg atgccgttct gatcaaattc gtcataaacc
     9181 ctgtaagcca tactagcctc aattttcaaa acaagcttca ccactctacg gttaaagtcc
     9241 ggaggatcat tccaaatatc catcggcatc tctcttatga aagtctcttc cgagcaagtt
     9301 ggatttttga ttcgggtcac tttaaacatt ctgaaatcat tctttaaccg gcaaaatcca
     9361 tagatatacc agttctgccc tttaaaaatc agctttacag gctctacgat tctctcggtc
     9421 ttttctccgt aggaactata ataatcaaag ttcactacat tccgatttaa aatcgctgtt
     9481 ttcagcaagt tgaacttctt ctgctccgta gaatcagagc cccacctgga gaaatcgaca
     9541 tcaatccagc tcgtagcatt tttattgaaa atagcagcaa gcttattcag cacgggctca
     9601 acatctggaa cattcagcgc attcagccct tgaagggaag agagaatatc catctgctcc
     9661 ttgtcagaca gcatcgattt gcccagcaca aactgatcaa gcaagcgaat gccgccgcct
     9721 tttcccttat tcgtatacac gggtattccc gccgcgctca gcgtgtcaat atcccgataa
     9781 attgttcgct gcgatacctc gaactgctcg gctaattgtt tcgctgttac ctgcttttta
     9841 tccaataaaa tatagacgat ttcgagcagc ctgttaattt gcacctctac caccccttcg
     9901 catcttactt acttcaccat tttgtaacct caaaaatact ataacgtata tagattaaac
     9961 atactctgtc aacaaccata gaaattgagg gactacatga atgaatgatg atattacggt
    10021 tcaacaagcc gatacatggt atcagaaggc cgaacagaag gccgtgcagt atttgacatc
    10081 tcttcaacag cgggttaggg atcaaacgga tctgcaaacc ctgacagccg atattcaatt
    10141 gtggaaaaaa aatcatgttc accacttctg gcgttctttg cttccacatc gcaacaaaac
    10201 accggatgca ctgggctatc gcaaatatat tggctggctg aaccgtacgg ggaaactgga
    10261 caattatttg gatcgaagca tttcttatat ttatatgcgc gatttgggca aggcgctcga
    10321 ttctcccgaa gcccaagccc gtataaagcg aaccatgtcg gatgtgaaaa aactcttgct
    10381 tcgctccacc ggcaccggtc aaggagagca gccagaattt atgaacttag ccgggctgta
    10441 tcggtgggct cagaaggaaa acattgagga cgctattatt tggctcattg gcaagctgaa
    10501 ccatgtatcc tcccaaattc ccgaaggaat ggatgcggag catgctcaga gaaaactgat
    10561 gaagatcatc attggcgtag ttcttcatgt tatggatgag atggatgacc gtattttgcc
    10621 ggatgagcgc tccaggcggc tggatgaagc gattcggctc ggttactcct atgggttgac
    10681 ctatcctttt atcgacgatc ttctggattc cgaaattttg aatgataagg agaagggcca
    10741 atactctcag atgataagaa gcgcactgct tactggctct gttccggaat caggagagtg
    10801 gaacggggaa cacagcgatt tcatccatta cgcatatgcg gagcttcgag aggcctttga
    10861 gtatattaag agctatcagc ggccagaagc cataagtact ttttttgaac aatcttatgt
    10921 attttttcat gctcaggatc tggatcgggt taaggagctc tcgcattccg cctacaccaa
    10981 cgaggaactc tacctgcctg taattttgaa atcctcctcc tctcgattga ttgtccgttc
    11041 tgtcatcagt gcgcctgagg atgagggctt tgagcagcga acattttatt acgggatcta
    11101 caaccagctt gccgatgatt ttgcggatat gttcgaggat atgagaaccg gagcggtaac
    11161 gccttatacg tattatttaa aataccgtag gctgcgtccc gatctgatta atccctatga
    11221 attatactgg acggtcatat cctacctgat tcatagcgtg tatcattccg atgccaaggc
    11281 ccgtgagatc atcctaaacc gtgcgattaa cggattaaaa cgctgtaaga aacgccttgg
    11341 ggttgataaa tacaccgaag tcatggacat tttcgcctcg ggaaaccccg agttcaatcg
    11401 gctcgtccaa cgtatggttc agcaagcgga tgatgtagat tttcttgaca agctgcttcg
    11461 ggatcaggtc gtcaccgttc tgaggaacag ccgcaacgac aaggagagct tcatcgatac
    11521 gctccaatcc gtccgcgatc agctcaatga acaattgcaa attcgcaaat cggacggaat
    11581 tcctctggtt acagaatcgc taattgagac tgcaaactac agtctccgag gagatggcaa
    11641 acgtcttcgg cccatcttaa cctgggccat gggtgtgaac gaatatgggc tggaggcttc
    11701 ggcaatcatg ccgctgctga aatccttgga atatatgcat acggcatctt tgattttcga
    11761 tgatctgcct tcacaggaca atgcctctac ccgtcgggga cgcccgacgc tgcatcaggt
    11821 gcatgatagt gccaccgcag aattgaccgg tctttattta attcaaaaag ccgttgaaga
    11881 gcaaacgtct ttgagcggat tcgatgccga atctgtgctt gccttaattc gatattcatc
    11941 ccaaaaagca ggcgaaatct gcctgggcca ggcgatggat ttagagtctc gtggaaaggc
    12001 actaacgctg gagcaactga atacgatctg cttttacaaa acggggatcg cttttgaagc
    12061 ttgtctcgtc atgcctgcca tccttgctca ggctgcagaa aaggaagttg cgtctctaca
    12121 aaaatatgcc taccatgcag gcattgcttt tcaaatcaaa gacgacttgc tggactctga
    12181 aggcgaaacg agcttattgg gaaaacccgt ccgtcaagac gtggaaaaca acaactcgac
    12241 gtttgttacc ctgcttggcc atgaaggagc ccgaagagcg atgtgggagc actactgcca
    12301 ggccatggaa accttgaatg aactgccgcg aagcaatgtt tttcttaagc atttattgaa
    12361 ctatatggta agtagagaaa aataaaaaaa agcacacctt ttaactcggc tcaagccgac
    12421 taaaaaggtg tgcctcacca tgtatttgca gaactttctc cttgtttagt atatagagtg
    12481 tccgctaagt tgtaaagcca ccgtcatcgc cagatatttc cggaattaac tcgaatactc
    12541 tactgttctt gccctcctct tatgaagctc tgggagcatg actccgagca ggacgataat
    12601 aacgcctccc cattgcagcg gtgtcacctg ctcatgaaga acaaacgatg agagcaacac
    12661 ggcgacagga agttccgccg ctcccaaaat gcctgccatc ccctcaccga tatgaggaac
    12721 gccaaccgcg aacaagactg gaggtataaa tgccccgaac aagcccagca ggaaaccaaa
    12781 taatagcagc tgactccaca gcataccgtt aaataaaaat tgcggtggaa atagaataaa
    12841 taccagcacg agtccgcctg taatcatcca agcgctgcga taggccggat gaatcgccgg
    12901 taacgctttg ccgctaaaca gaataaataa agtgtagctc acagccgaca acagtccaag
    12961 ggcaatgccg atcattggaa agttcccatc cctttgctcc ataagccctg ctgcgaacaa
    13021 cgtacctccg agcagaagtc cgagcgttat tagggtaatc ccatttgggc gttgccgttt
    13081 gctaacggct tgaaccagca cactgatcca cgtaaactga aacagcagca caattgctag
    13141 cgatgcggga atataacgca gtgagtgata atagagcaag ccggtaatgg cagtcggtgt
    13201 tccggctaac attaacagaa atctatgctt ccagcttagc cttgccgagc gattcgagga
    13261 tgccttcgtt agcgcattta cgctcttctc ttctttgcga cgttccttcc aaccggtata
    13321 tatagccaat agccaagcta ggatacaccc cgtcaacagc tgcgtaccca ccacttcgcc
    13381 tagctgatag ccttgcccat atgcgaggac aacaatggtc gacagcacac catagctgct
    13441 cgctccaatt aacacggata ataaatattt cattttcatt tccttacagt tcctcctcga
    13501 aataaacaaa ctaggccaaa aacgcaaaaa atcctaacta cgaaataaga ataagttacc
    13561 attctcattc tcgtagttag gaagatacgg cttccagtag aaacccccgc tccgttatat
    13621 tactatagct ccgcgaggtt atacgaagaa atatgcgatt caatcaaaac acatattaca
    13681 tgacaagtaa gctatctgtc aatccctcag attattacgt aacatttccc cactctttgc
    13741 ttttcttaca tactcggttt gaattcccgc aaccattcag ttaatcgcag caattcaatt
    13801 cccgcaagca taacaattcc gataccatgc gtatcgttca gttgtggaag cagatcatgc
    13861 ttataataat ggctggaatg cgagtatccc gacccccgac atacaccatg caggttccct
    13921 ttcgcatcaa tgctatggcg ggtcaagcct tcccaagcac gaacagcgct atttgtgtat
    13981 gcggttcggt tcgttaacca tccattccgg atgccgcgcg cataagcgta gatgaacatc
    14041 gcggtgcagg aggtctctaa gtaagcatca ggctcattaa tgacctggcg ccataagcct
    14101 tcttcacttt gatggacgag atatccagcg ctaagtgtcc gaaacatctc cagcaattgc
    14161 tcccgatgcg gatgctgctt cggcaagacc gtcaacagct cggataagga gaacagcacc
    14221 cagccattgc ccctccccca tgggactcct gtcgccaatc cttgctcaaa gtcgtaaaca
    14281 tgagacatca gcttctcctc agggatgaat aaatactttc taaatagcag aaactgtctg
    14341 gcggcatcat caatatactg ctcatcccct gttaatcgat aatatcggca tagaaaagga
    14401 acactcatat acagatcatc tgcccacata gtatgctcat cctggaaatg cttgcgataa
    14461 aaagctccat cgggcaatct ctcctgaaca tccctaatat aattcccgat ttcgcatgcc
    14521 agtgattcca cacctgtcat ttcgagattg tcccgatata cctcaagcat ggtcgacccg
    14581 aatgagccgc aatcatccag actgtcgata tctgcaatag attgattaat ccctgtggcc
    14641 ttatattgct tataatccca ttgtgtatat ggataccact tcacggtctg cgcgacatgc
    14701 gccgccgcat aagcaacaag atctggccgg gacagttccc ttcctgtctc caccaagccg
    14761 tacagcgtca cacctacagg gtaattccat ttcccgaaca acggagcttc caagtacgga
    14821 cgtatccatg ttccaggcaa atcaacacgc caatatgttc cttccccacc gtctgcatga
    14881 acccgggaca gatctgtcag atcaccgaga tcagggatgc actcctcagc aaatgggcct
    14941 aaaaacaacc aggctcccaa gtacccctga acagcgactg gaggcataaa cggaacaact
    15001 tcatctccca accctactgt tacttttgtt ccccatgacg ggccaagcgt atcacgaatc
    15061 atcaattgat gcggcccaaa tgacaattcc acagtaactc caaattctcc ggcttgttcg
    15121 gaatgatata tcgctgtacc atcaatccaa attgttgtag ggccgaaact atgtccagta
    15181 atccggtaag cctgagcttc caccccgtta gcgtgaaact gcgtccatgc gaaggcgctt
    15241 tgccccttgg ctgcaccaaa cagccgctcc attggcgtca aaagatactg ctctttagtc
    15301 caatcgggac gtggacacca ttccaatatt ccatcaaatt cagtttgccc cgcacgcggc
    15361 agctctgcca ccgctctagc cagcggctta ctaaacagcc agccttcctg gccgcttctc
    15421 tctttagaag ctacgatggc attgaaaatc acccacttgc tgctcgtagt accaaagtgt
    15481 ccaccgaatc cggcgcgcgt cttcgtaaat ttaagcacga tatcattcca gcctgctctt
    15541 agtatagaac ggcattcccg gttcactttt ggacgttcct cttgaggctg cgaacggtaa
    15601 atactgcggc cgttcacgaa cacctccatc ggcccccatg ccgtagcaag ccaggtcatt
    15661 tctgtttccg gctcatcgct ccaaaccatg ctccatgcgt aggatacttg ccctacttcc
    15721 gcctcgggaa accgttctgc caaatcgaag acatatcgaa agtcattcgc gcgctgaata
    15781 ccttcccgat taaaagcgcg ataactgaac ggctccgctg gatgatcagc tacatagcga
    15841 tttgcaagcg atcgcaatgc agctttaata tcggttcctg ttttgtcata aatactgttc
    15901 tcatgttgtt ttaacatcgt actcattctc ctaattcagc tggactgcca cgctggcagc
    15961 ctgcttttga atttgtcaaa ccctgtacag aggtcaaatt ccgacaagta aacctttatc
    16021 gaaatcgtag cataggctga tgtacgcgtg aatgagaatg atgcccgaat gtattcaatt
    16081 tttactgaaa aagagtattg agaggatcaa ttacgatata aaaatccccc tagcctccac
    16141 ctgctgaatc tggatcagat tcgtcgttcc cgcctgtcca agcggtaatc ctgcagacag
    16201 tacgacggta tcgccaaggc ccacatatcc tgtctttaat gcccgccgga tcgccttatc
    16261 aaacatttca tccgtagtcg atacctgttc gccttggaag ggaaagacgc cggagagcaa
    16321 acagatcgca gacagcacgt gccgatcatg ggtaatcgcc aaaattggcg ccttcggccg
    16381 atatttcgat accatgcgag cggtaaagcc gctctcagtt gaagtgatga tcgctttagc
    16441 ctcaagttcc agtgaagcgc tcaccacccc ttggctgata acctcggtaa tattggttac
    16501 atgctggact ctttttcgat taaattgctc ccgatagtcg atggtagact cggcctgttg
    16561 cgccactcta gccatggtct gaacggacgg tatcggatat ttgccggcag cggattcccc
    16621 agagagcatg acgacatccg ccccttggat cactgcattg taaacatcgc tgacttcagc
    16681 acgcgttggc cgcggattga cctgcatcga ttccagcata tgcgttgcaa cgatgaccgg
    16741 cttgccggcc agattgcatt tatcgatcat ttctttctgc atcgccggga cattttcgac
    16801 aggaacctcc acacccagat ctccccgggc caccataata ccgtccgaag cctcgataat
    16861 gtcgtcgagt tcccgaacgc cttcatcgtt ctcaatttta gaaataatct gcacatgccc
    16921 ggcaccccgc tcctccagaa gccgccggac ttcgcgaatg tcatccccct tgcgtacaaa
    16981 cgatactgcg atcatttcga tcccctgttc cagaccgaag tcgatatgac gaatatcccg
    17041 ttcggttaca cccggaagcg tcgtccggat tcccggtaaa tttacgccct tgcgaggttt
    17101 aagcgtgccg ccgctcttga tatgacagcg aatctccgta ccctcaacct caatgacatc
    17161 tagctcaatc aggccgtcat cgattaagat gcgatcattt ttcttcacca ccgcaggcat
    17221 ttcggcataa ttgacggaaa tccggcgcga atcgccttct atattttcag tcgtcaagat
    17281 cagctcctcg cccgccttta attggctgga cgcctccttc agcttgccga ttcgtacctc
    17341 gggcccctta atatccatca tgaccggaat atatgcatcg acctccttcg cagcctcacg
    17401 aaggcggctg atccgctctg catgctcctc tggctccccg tgagccatat tcaggcgtcc
    17461 caccgtcatt ccggctttga tcatttcttt taaaatttct actgtgtcgc aagccggccc
    17521 aagtgtacaa atgatttttg tccgcagcat gaaattcctc ctcgatttga aattgcttaa
    17581 caagactcct tatgaagaac agtgttccct ggaaggattc gccttatgtc gcatctcaaa
    17641 aataactaac cgtagatgat atactttgaa ctagctaagc taatcaaata gcgaaatatt
    17701 tttgaataaa tgaacttttc ctatgggttg cgactcttat aggggagtga ggtgaagcaa
    17761 tgaatgcggt tcgatacgtg aaaaaagcaa aaaggggaaa taaagatgcg ctccttcaat
    17821 tgattctggc cgagaaagac agctattaca ggctggcgct cacctatatg ggcaattcgc
    17881 atgacgcgat ggatgccatg gaagagatga tcgtaaaatt atacgagaat atcggccagc
    17941 tcaacaagga ggaagccttc tacagttgga gcaagactat tctagcgaac tgctgcaaag
    18001 ccttgcttcg caaaagggat aagctggtgc tgatagacga tgtcagcagg gacggcgatc
    18061 tggccgcgga ttatgatccc cagttcggcg acccttatcg acgcagcgat cagcagatag
    18121 atatccagaa gctgctgctc catttgaacg agcagcagca agaagcgatt caattgaagt
    18181 attggcatga cttcgattac caaacgatcg cggagatcac gaatgtacct ataggtaccg
    18241 tgaaatcccg gatttttcaa ggactgaaga agctcagaga actctacggg gaggatatgt
    18301 atgaatcacg ttgaaaaacg attagcggaa gagaaaatgc gtatagattc cgtaactgca
    18361 cccgaggagt tggagacacg attaagagat gcgctgaaca agacggattc tcaaagaacg
    18421 aaaagacgga ttccctcggt ctggaaggct gcggcggtcg ctttgttctt cctcgtggtc
    18481 ttcgggtatc attacaatgc cttcgcttat tacggcaaga agctgcttgg attcgatgag
    18541 ttaattggcg gttcacagct gcaggaactc aatgagcaag gcatggggca aatcgttgat
    18601 aaaaagacga acctaagcga tggaacggaa ctcacgatta acggcatcat gacagatgca
    18661 aaccaactga tcatgtacta taccctgacg aatcccgagg gcattgagga taacggcatc
    18721 gacctgttcc ggccatcgaa attcaccggc ttcttaacga actccaacct agagagcggc
    18781 acgtcgttgc aaaatgagga acagacggag gtgaagggaa cgatgtcctt tcagcccgtg
    18841 agcccttttg ccaagaagct gaacttgcat tattgggatc ggacggaaaa taaccaactc
    18901 atcgaacaca ccatctcctt cccctatgat ccaaaccagg cgatgcagac cgaggtgagg
    18961 aagtcgctcc gcaagacggt aaaagtcgac aaaggcacgt taaactttca atccattacc
    19021 gccacgccaa cgatgaccat gatcgaaggc tcgctaaacg tcgataactt cgatcgcctt
    19081 ccttccgcat taagcggaat agagctaatt gcgaacggca cgcctgtaga attgatagga
    19141 agcggacatg gatcttccct gggcggcaga aagttcgatc ttcgttacgg ggcactgccc
    19201 aagcctttga catccctgga gctcgttatg aaagagtttg tcggctacca gcagttggat
    19261 cagagactgc ctctctcttc ggctggcaac gagcctttct ctctggatgg caaaaaactt
    19321 tgggtgaaaa aagcagccgt cacgtcccaa ggcgtggaga ttacaatcgc tacggatgac
    19381 gatatcctgc ttgatggcgt atctattgaa acgcagaacg agacaactgc tctaaaaacg
    19441 accgtaaatc aaatcgaaac caagctggac gatgggggaa ttttgaagga gcgcacttta
    19501 ctgttcgata cttcagtcat gccggaatac ttgcatatca aagggataca ttatatgaag
    19561 gcatacaata aagtgattga aatccctgtg aagtagaaga gatatattcg tgaagcaaga
    19621 tacgcaataa attatcatcc gccgcttttg gcggattttt ctttagtgcg gaataaggaa
    19681 gttccagtct ttcacaacat gaaaaggaga gagcaacgct gccccctcct aataaaaaaa
    19741 ccgtcgatag cttgtttcct ttacatatca gcttttcctt tatccgacct tatccgagca
    19801 taaccttccg accactcttc gcactctcga tcgcaccgag taccatggcc atgctgtgga
    19861 tgttatcgcg gctgtcagtc tcggctggac ggccctcctt gagggcctgg aacatttcgt
    19921 ccagacaacc ctcatgccct ggcttgccgc tccaattcag aggcacttca atccgcacca
    19981 tatcgcgaat gaacttcttc tccgccgcat cgtcagccgc cagttcgcta gccagtactt
    20041 ccgcataagg cgcatgaatc ccgtcccaaa tggccgttcc cttctcgccg acgatccgcc
    20101 aatcgccctc ccaggacgtg ggaacgcctt ctgcacacca ggagccgcgg tagctgaata
    20161 cggagccgtc cgacatttca tagatacaaa cagcggatgc attccctttg taccacgatc
    20221 ccgggggatt aaattcatgg cagtagaccg acaccgggtc tgcgccgacg atgaaccgag
    20281 cttggtcaaa ggtatggatc gccatgtcca gaatcagcgg actctccatc acatcgcgga
    20341 acccgccgaa atgcggccca aggaaaaaat ctgcattgat catgccgagc ctgccgattg
    20401 tgccggatga tatcagctcg cgaagcccgc ggatattgac atcgtaccgg cggttctgca
    20461 taaccgacaa cgacctgccc gtggcatccg ccgtttcgat gatcttcctc gcttcccgca
    20521 tcgtagccgc catcggcttt tcgccaaaga catggcagcc atgcttcatg gctgtcgtac
    20581 tgatctcata atggctgtca ggaatcgtca cgtcgataac taagtccgcc cccgtatcga
    20641 caatggcctg ctccagcccg gtgtatacgc cgcattccag tccatatgca tcccgtactt
    20701 tctcagcctg gccaatatag acatcaacaa ggccaacaat cacggcatca tcccgcttca
    20761 gcagctcctt gatccacacg ttcgacattt cgccgcagcc ggcaaccaca atcctatgct
    20821 gcttactcat tctctccacc acctcttgca gctatataaa gtttcacact cttgcaagac
    20881 ataaagtctg aaatttcaac ctatttcaac ctatatagtt gcgtctatcc aaccttacag
    20941 cgggttcggc acgaaggctc cgccgcggca ctgcttcaag taattcagcg catgcacctg
    21001 cccggtcatc tccagttcat cgcgataaac cgggtcatgc cagccttcga tatcgatcgt
    21061 tcccttgtac cccgcttgac gtaaaatcgt aataatatcc gtccagttcg tgtcgccaaa
    21121 tcccggcgtc cggtgccaga caaattcctt cggcccgtgg atgccgtatt cctttacgat
    21181 atcccaagcg atcgtcgcgt ccttgccatg aacatggaac accttgtcca cccatttccg
    21241 aagctgcgga atcggatcga tcaggctgac catctgatgg cagggctccc attcgagtcc
    21301 gagattatcg gccggaacct cgttgaacat catctcccaa gcctgtggat tgtgagcgat
    21361 attccagtct cccttccacc aggtaccgcc catgtcgcag ttctcgaacg cgatccgtac
    21421 gccccgatca gccgcacgct tggccagttc tccgaacact tccttgaagc gcggcagcga
    21481 ttcatcgatc ggacgatccg tcaggcgtcc ggtgaagccg ctgacgatat ccgccccgaa
    21541 cagatgcgca tggtcgatgg cccgctccca gctagccaac gtatccgcat tgtccccttc
    21601 gcctgtcagc gggttgccga atacgccgat gctggagatg actacgccat gctcatcggt
    21661 cattttgcgc acctgcttgg caagctccgc caaatcgatg ccgcccgtcg tttgccaaaa
    21721 ggtcaggcta aaggactcaa agccatgcgg caaaatttgc ggaatgaccc gcaccgcatc
    21781 ctgtccgcct accagtgtgc ctatacgtaa caaatgattg ccgtgttgca tttgccaacc
    21841 actcctatat tgagtatatt gtgaagcata aacccattgt atagcacttg cttgattata
    21901 tctctataca atcttgtgct ttttcagttc aatattgcgc tagaggagct gtggctgaaa
    21961 tgacgcaacc ccaggaattg cgggagcata cgtattttaa cgatccatcc tatcccttta
    22021 atatatttcg tctttgccag gagcagcagc agaagggcac cccttcattc catttgcatt
    22081 ggcatgatca tttcgagatt ctgcttgtat ccaggggaaa ggccgtattc tatattgaca
    22141 gcaaccccta tgaagcacag gccggcgata tcatcatcgt tccctctggc gctctacatg
    22201 cgggttatgc agcagacgac agcgcgctgg aatattgcgc catcgtgttt aacgtggcgc
    22261 tgctccggca tggcaaagcc cccgacccga agcatgcact ctatataacg ccctacttgg
    22321 acggggctct gctttttcct gtcaagctca gtcatcaaga cacggcaact ctgcggttca
    22381 agcat
//
