LOCUS       NZ_LT732548            11935 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Paenibacillus bouchesdurhonensis strain Marseille-P3071T, whole
            genome shotgun sequence.
ACCESSION   NZ_LT732548
VERSION     NZ_LT732548.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus bouchesdurhonensis
  ORGANISM  Paenibacillus bouchesdurhonensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1
  CONSRTM   Urmite Genomes
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2017) URMITE, 27 Bd J Moulin, 13385 Marseille
            Cedex 05, France, 13385, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900155685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:11:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,206
            CDSs (total)                      :: 5,108
            Genes (coding)                    :: 5,019
            CDSs (with protein)               :: 5,019
            Genes (RNA)                       :: 98
            rRNAs                             :: 8, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 3, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 31 of 89
            Pseudo Genes (incomplete)         :: 75 of 89
            Pseudo Genes (internal stop)      :: 9 of 89
            Pseudo Genes (multiple problems)  :: 21 of 89
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:18:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3781671
            Orig. end                         :: 3793606
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT732548.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11935
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="12"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11935
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11935
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6935](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6935)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(545..>694)
                     /locus_tag="CZ379_RS21160"
                     /pseudo=""
     CDS             complement(545..>694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012294977.1"
                     /locus_tag="CZ379_RS21160"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="FMN reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LMIEEKDFHRKEIVNDDILFRMQRLVEDTVLLVDAYSSIRKIKDA
                     EYDF"
     misc_feature    669..683
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.9"
                     /tool="antismash"
     gene            complement(736..1791)
                     /locus_tag="CZ379_RS21165"
     CDS             complement(736..1791)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202354.1"
                     /locus_tag="CZ379_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_110933433.1"
                     /transl_table=11
                     /translation="MEQYRIQKNNGLEFGLYSIGDHLPNPHTGSMISAQQRIHELIEAS
                     KLADEAGFDVFAVGESHQTHFTTQAHTVILGAIAQATKNIKIASSATVLSTSDPVRVYE
                     DFATLDLISNGRAEIVAGRGSRVGAYSLLGFDVRDYEELFEEKMELLLQLNNEDKVTWT
                     GQFRAPLENAYILPQPQNGRMPIWRAVGGPPASAIKAGYAGVPMMLTTLGGPAINFKIS
                     VDAYRDAAERSGFDAAALPIATTSLFYTAETTQDALREYYPHANSGMQALRGSGYPKQQ
                     FAQATDYRDALMIGSPQQIIEKMLYQYEMYGQQRFMAQIDFGGVPFDKIAKNIELIATK
                     ILPEIKKHTAK"
     gene            complement(1823..2764)
                     /locus_tag="CZ379_RS21170"
     CDS             complement(1823..2764)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202355.1"
                     /locus_tag="CZ379_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ring-cleaving dioxygenase"
                     /protein_id="WP_110933434.1"
                     /transl_table=11
                     /translation="MYTISGHHHISMLTKDARINHQFYRQVLGLRRVKKTVNQDNPSMY
                     HLFYGDLTGSAGTELSFFEMPNAGKTVRGTNAITQIGLLVPSYESLIFWKNRLEAWKVD
                     HGEITKYAGRDALHFEDPEGLRLVLLNHNGADIPGNWSAWEGSDVELEHRILGMGTVEI
                     TVRDLERLAKVLRDLFGYTEVSRSMDEAVYQSITGEAFGEIVIKQQEGARERPGKGSIH
                     HLAIRVKNEEELRYWDMVVKENGFHSTGVVDRFYFQSLYFRDLNGILFEIATDGPGFTA
                     DSTVEELGQALDLPPFLEERREEIEAKLVPID"
     gene            complement(2812..3255)
                     /locus_tag="CZ379_RS21175"
     CDS             complement(2812..3255)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205511.1"
                     /locus_tag="CZ379_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_110933435.1"
                     /transl_table=11
                     /translation="MRNNTIGSLIWLRLVRFTNQSNQMSNEFLKRFDLTTAQFDTLMQI
                     RIYQPLTQMELAEKVTVTQGGISRMLARLEKEGYIVRKQDWKTKTISLTAKAEAVLNQV
                     MPEQLAFQTSFFDEVLNDEEQKTLYTLITRVHKHSQKKELPPE"
     gene            3474..4457
                     /locus_tag="CZ379_RS21180"
     CDS             3474..4457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638727.1"
                     /locus_tag="CZ379_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="WP_110933436.1"
                     /transl_table=11
                     /translation="MTKPVKQNEPIVTHIYTADPSAHVFEGKLYIYPSHDLDHEMESND
                     NGDQYDMEDYHVLSMEDINSPCTDHGEALHLRDIPWAKQQLWAPDAAYKNNTYYLFFPA
                     RDKDDIFRLGVATSSSPAGPFTPQPDYMPGSYSIDPAVLVDEDDKAYIYFGGLWGGQLE
                     KWQTGTFEPDADGPTANEPALGPRAAELSEDMLTFKEAPVEISIVDEDGNPLLAGDEDR
                     RFFEGPWVHKHSGYYYLSYSTGTTHKIVYAMSKNPMGPYVYKGTILTPVLGWTTHHSIV
                     QFKDKWYLFYHDSSLSGGADNKRSVKFTEIKYNEDGTIQTIDPYNN"
     gene            complement(4772..4888)
                     /locus_tag="CZ379_RS26785"
     CDS             complement(4772..4888)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638725.1"
                     /locus_tag="CZ379_RS26785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YjcZ family sporulation protein"
                     /protein_id="WP_234404970.1"
                     /transl_table=11
                     /translation="MGELGGIGGCSCAGVFTSTGVILVLFILLVIVSRSFVY"
     gene            complement(5001..6935)
                     /locus_tag="CZ379_RS21185"
     CDS             complement(5001..6935)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019003927.1"
                     /locus_tag="CZ379_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_110933437.1"
                     /sec_met_domain="YcaO (E-value: 1.5e-76, bitscore: 256.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 6e-117, bitscore:
                     388.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSVVIVGEGILADAVYKRMSEFLPVRRKDFSETIPVTDLVLVLE
                     EQDSSSIYLEAEQVLRPRGTPWLCAYISLGEGVVGPLIHPGKFGCFQCAETRLALAGSN
                     RQEVDEMLMKLVSPDYAPNYTAELSPAGSGYLAHIIAAEVTKVLRGDKANTEEHVYLID
                     LKNLSSTIHYVLPVGTCSVCGQLPDDSPELAKISLQKCLKVNNTYRCRAMSDLQRVLLR
                     DYWDSRTGVFNDKKWSLSSSFAGAAINLPLGFYDEITGGRSHSFLDSELAGILEGLERY
                     CGVAVRGKRTVMHGSYSQFKGAAIDPSTVGLHAEGRYEQPDFPFIPFDPDAPMEWVWGY
                     SFLEERPVLIPHLLAYYSLGGGGGFVYETSNGCAVGNSIEEAVLHGIFEVVERDAFLIT
                     WYAQLHVSRLDYISSGDSELVLMIQRLRAVTGYEVSLYNMTMENGIPSIWALAKGGTEQ
                     CVNLLCAAGAHLDPVQAAKSAIHELAVMIPTVERRWEERRLEAEAMFGDSELVQYMEDH
                     SLLYSLPQAERRLHFLLEDSRPLCTFAEEFPSVPAHEDLTDDLRQVLQIFRRLQMDVIV
                     IDQSSSETRRNGLRCVKVLIPGMLPMTFGHHLTRLSGLDRVLEIPMKLGYVNHTLTPQE
                     LNPYPHPFL"
     gene            complement(6932..8470)
                     /locus_tag="CZ379_RS21190"
     CDS             complement(6932..8470)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006677776.1"
                     /locus_tag="CZ379_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_110933438.1"
                     /transl_table=11
                     /translation="MSLLEEGTLVIGSGPILLSLAESWYEFGLSKLTVYVTSKEPIDTG
                     KLKEFCEHAYGREAETSLKIIAAARDEDLNWRAIVRPFQFILYVSEHGGLDELLKLQNA
                     CIAERRQMLPGILVRGMGMAGPLLNCDGNGRWESAWRRIHSSVFPESRCEKGLSVAAAG
                     LLSNLLVHEWHKAITAENDAYSWNHCFLLDPVTLTGGWHQVLPHPLVFGYEAARPVENI
                     ERHFGDNNERANPQKWFSALNQLTSTITGIFHAWEEADLIQLPLAQCLVQPVDLLSEEP
                     APLLPVIIRSGLTHEEARRESGLAGLEAYAARMIPLMFSWLPSHQQQEINIGAGCDLAE
                     AVGRGFRACLAKEFGKRTLSHEPTVLRIACTQIKDVRCQYYLQALSIIEGEPVIAVGEP
                     LLGFPVVWVNRGSSWYVSADLSFTLALRQSLQKALDQREAASISAVTWRNNEWQETPVP
                     DSGSLDYGSLMQSAVRTLKQHHKRLEVFNMPSKSLWGKSPFEIYGVSLEEGGVY"
     misc_feature    8544..8558
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.02"
                     /tool="antismash"
     gene            complement(8623..9912)
                     /locus_tag="CZ379_RS21195"
     CDS             complement(8623..9912)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="CZ379_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_110933439.1"
                     /transl_table=11
                     /translation="MFKTLYVRIVFYYLAAVLIGVIVAWAAAIFIFQDSAERYTERELT
                     RKGQQLIQLYSQAQPEDQQTFLENAAQLSSVRLKVTAPNSQEIQLFNWPDADNFCDCDI
                     SVTMPWPLDEGVYQIELAQAAFSESSGLTEITVILVIVLLVGGLIILFFARRLVTPVQT
                     VTAAAKQLATGDFNVRLSENQRDEMGTLAKAINHMAAELGELDRERQEFVANVSHEFQS
                     PLTLVKGFSAMLLEGSLKAPERSRALQIIMQESERLSRLSENLLRLAALESERHVMAPT
                     HFDLAEQIRRTVLTFEALWSEKQLEVEMKGERTMIHADEELLSQVWINLMSNAIKFASA
                     GGRIAIELKADQDQVEIRFYDDGLLIADEDKERIFSRFFKADRARGRNIEGNGLGLSIV
                     KKIVDIHQGSIYISSEGERGKAFVIQLPLL"
     gene            complement(9905..10579)
                     /locus_tag="CZ379_RS21200"
     CDS             complement(9905..10579)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638719.1"
                     /locus_tag="CZ379_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_110933440.1"
                     /transl_table=11
                     /translation="MIKILVVDDDPFIRELVRLALRSDDYNILEAKNGTEAIAFIHEER
                     LELVIVDIMMPGTDGLEVCREIKRYFDIPVLMLTAKGTNIDKVAGFQAGTDDYVVKPFD
                     PKELSYRVKALLRRYRFDRGYSLQVGQLYLNAQRQVSVGEKEVSLPPKEFELLYRLASQ
                     PNRTLTREQIIEHVWGSDFEGDERTVDVHVKRLRERFSELTDSFEIVTVRGLGYKLEVK
                     HV"
     misc_feature    10598..10613
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.21"
                     /tool="antismash"
     misc_feature    11110..11124
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.06"
                     /tool="antismash"
ORIGIN
        1 acaaactccg tatgcagcaa aatttgttgg ctggttcgtt cgaccttgtc ttcatcggag
       61 aatagatctt ctatttttga aacaaggctt acctttaagc ggacagcttg atactgttca
      121 aaaatatgat tgactctgtg cagcaggttg tcagaaatgg cctcattaga ccgaaccgat
      181 tcagcaagct ccagcagaac ttctctcatc ccctgctcca ggcttcccct cttcacttca
      241 tgttggttgg cttcattaat caccgttaga aaatagtttt cacgggataa aattgggcac
      301 atcggactct ctccttagtt agtactcctt aaattaaatg tattaatgta ttcaatacat
      361 ttatatcact taatgatcta attaacaata ttccatgggc aatagcgaca gctatcaagg
      421 acttaatcaa ggagttccaa atgcacccca tgcttaccac gagaaaaagg accgtgcgcc
      481 cctcttattt tggggctgca caatcccttg ttgcttactt cgtctccatt ctaattgcct
      541 gcctttaaaa atcatactct gcatctttga tcttgcgaat gcttgagtat gcatcaacca
      601 gcagtacggt atcctccact aaacgctgca tacgaaacag aatatcatcg ttgacaattt
      661 ccttgcggtg aaaatccttt tcctcaatca ttagagcctg aaatagctac gatcttcata
      721 tccaactcct ccttattatt tagccgtatg tttcttgatc tcaggcaaaa ttttcgttgc
      781 aatcagctcg atattttttg cgatcttatc gaagggcacg ccgccaaaat cgatttgagc
      841 cataaaacgc tgctgaccat acatttcata ttgatagagc attttttcaa taatttgctg
      901 cgggctgcca atcattaacg catcacggta atctgtagct tgtgcaaatt gctgctttgg
      961 atagccgctg ccgcgtaatg cctgcatacc ggaattcgca tgtggatagt actcgcgaag
     1021 tgcgtcctgt gtagtttccg cagtataaaa taaacttgtt gtcgcaatcg gtagcgctgc
     1081 ggcatcaaag ccgctccgct ctgcggcatc acgatacgca tccaccgaga ttttgaagtt
     1141 aattgcaggg ccgccaagcg ttgtcaacat catgggcacg ccggcatatc cagccttaat
     1201 cgcgctcgcg ggcgggccgc ctacggcgcg ccaaatcggc atgcgaccat tttgaggctg
     1261 cggcaaaata taggcatttt cgagcggtgc acggaattgg cctgtccacg ttactttgtc
     1321 ctcgttgttc aactgcagaa gcagctccat tttctcttca aataattctt cataatcacg
     1381 tacatcaaag ccaagcaagc tgtatgctcc tacgcgcgaa ccacgtccag caacaatttc
     1441 tgcccggccg tttgaaatta aatcgagagt ggcaaagtcc tcatacactc gtacaggatc
     1501 agatgtactt aacaccgtgg ccgaactggc aattttaatg ttttttgtag cctgtgcgat
     1561 cgctcccaag atgaccgtat gcgcttgggt agtaaaatgc gtttgatgac tttcaccgac
     1621 ggcaaacaca tcaaatcccg cctcatcagc cagcttgctg gcttcgatta attcatgtat
     1681 acgctgctga gcgctaatca ttgagcctgt gtgcggattc ggcaaatgat ccccgatgga
     1741 atacaagccg aattcgagac cgttattttt ttgaatacga tactgttcca tgcttctctc
     1801 tcctttttct catgctatct tgttagtcaa tcggcaccaa ttttgcttca atttcttcgc
     1861 gccgttcttc caggaaggga ggcaaatcca aggcttgacc aagctcctca accgtcgaat
     1921 ctgccgtgaa tcctggaccg tccgttgcga tttcgaataa aataccgttt aaatcacgga
     1981 agtataggct ttggaagtaa aaacggtcta caactcctgt ggagtggaag ccattttctt
     2041 tgaccaccat gtcccagtaa cgtaattctt cctcgttctt aacgcgtatt gctaagtgat
     2101 gtatgcttcc ttttccgggc cgctcacggg cgccttcctg ttgcttaatg acaatctccc
     2161 cgaaggcttc cccggtaatg gattgataaa cggcttcgtc catagaacga gacacttctg
     2221 tatagccaaa tagatccctt aacacttttg ccagccgttc cagatctcgt accgttattt
     2281 ccaccgtgcc catgcctaaa atgcggtgct ctagctcgac atccgagcct tcccatgctg
     2341 accagttgcc agggatgtct gcgccattat gatttaacag aaccaaccgc agtccttccg
     2401 gatcctcaaa atgcaaagca tctctgcccg catatttcgt aatttcgcca tgatctactt
     2461 tccatgcttc aaggcggttt ttccagaaaa tcaggctttc ataggacggg acaagtaaac
     2521 cgatttgagt gattgcattt gttccacgaa cggtttttcc cgcattgggc atttcaaaaa
     2581 atgacagttc cgttccagcg ctccccgtta aatctccgta aaaaagatga tacatactgg
     2641 gattatcctg attaacggtc ttcttcaccc tgcgcagccc taatacctgg cgataaaatt
     2701 gatgattgat tcgagcgtct tttgtgagca ttgaaatatg atgatgtcct gaaatggtat
     2761 acattctaac tcctccttaa cttgactaat caagtgttag ggtaaaaaaa attactctgg
     2821 cggtaattct tttttttggc tgtgtttgtg tacacgtgtt attaatgtat atagtgtctt
     2881 ttgttcttca tcgtttaata cctcgtcaaa aaacgacgtt tgaaatgcta gctgctcagg
     2941 cattacttga ttcaaaacag cctcagcttt cgcagtcaag ctaatcgttt tcgttttcca
     3001 gtcctgcttg cgcacaatat agccttcctt ctcaagacga gcgagcatac gcgaaattcc
     3061 gccttgggtt accgtcactt tctcggctaa ttccatttgc gtgagaggct gataaatacg
     3121 aatttgcata agtgtatcga attgtgctgt cgttagatca aaacgtttta gaaattcatt
     3181 ggacatctgg ttgctttgat tcgtaaaacg cactaaacgc aaccaaatta acgagcctat
     3241 cgtattattg cgcatatcgc ttcagctccc ctccttcgct aatcccacta tcactttacc
     3301 actcaagtga caaggtgtca agcaagcccg cccactcccc ctcagacttc ggaatgaagt
     3361 aaagtttttt ggtgaaaatc aaagtatttt ctgggtttgc tccagctttt attttgctac
     3421 aataaaaggt aacaatgcag catttcaagg acgtaaccaa ggaggtaatt ccaatgacca
     3481 aaccagtaaa acagaatgag cccatagtta cacatattta tacggctgat ccatccgcac
     3541 acgtattcga aggcaagctg tacatctacc cttcacatga tctggatcat gaaatggaat
     3601 ccaatgacaa tggcgatcaa tatgacatgg aggactatca tgttctgtcc atggaggata
     3661 taaactcccc ttgcaccgat catggcgagg ctctccatct tcgtgatatt ccttgggcca
     3721 agcagcagct gtgggctccc gatgccgctt ataagaacaa tacatactat ctgttctttc
     3781 cggctcggga taaagacgat attttcagac tgggcgtagc taccagttct tcgcctgcgg
     3841 gccccttcac gccgcagccg gactacatgc cgggaagcta cagcatcgat ccagccgttc
     3901 tggtcgatga ggatgacaaa gcgtacattt atttcggagg cctgtggggc ggacaactgg
     3961 agaagtggca aaccggcacc tttgagccgg acgcagatgg gcctactgca aacgagcctg
     4021 cgcttgggcc aagagctgct gagctaagcg aggatatgct gaccttcaaa gaggcgcctg
     4081 tggaaatttc catcgtggac gaggatggca atccgctact tgctggcgac gaggatagaa
     4141 gattttttga aggcccttgg gttcataaac atagcgggta ttactacctg tcctattcaa
     4201 ccggtactac gcacaaaatc gtgtatgcca tgagtaaaaa cccgatgggg ccttatgttt
     4261 ataaggggac aatcctgacg cctgtcctgg gctggactac ccaccactct atcgtgcaat
     4321 tcaaggacaa atggtatctg ttctatcatg acagctccct gtctggaggc gcggacaaca
     4381 agcgcagcgt taaattcacg gaaatcaaat acaacgaaga tggaacgatt caaacgatcg
     4441 atccttataa taattaagaa ggaaacaaaa taggatcgtg tgcccctctt attttggggc
     4501 tgcacgatcc cattttcaga actcggtcga acattccgca actatatcaa tagacaattt
     4561 gaaaatgaag ttcaacaatt aaactagctg aattctaaga acatccgctt gataatgcaa
     4621 aatattgatt acaaaaagaa agcccaagcg gtatgccact tgagctctgt ttcgagagga
     4681 catctttgct attatacagg atgactcctt ttatttactc cctgtgaaac agatcatttc
     4741 ccgctgggag aaggtttgtt ggatacaata attagtacac aaacgaacga gatacaataa
     4801 ccaacagaat gaagagtacg agaattacac ctgtgcttgt aaatacgcct gcgcagctac
     4861 agccgccgat tccacccagt tcacccattt tgacatcctc ctccctcttt tgtttatgtt
     4921 aaattgtatg agcataaggg atttatggac tggacgtttt ttaaaatggg cgattaacct
     4981 ttcgacgact tctgccatcg tcacagaaac ggatggggat agggatttag ctcctgtgga
     5041 gtaagcgtat gatttacgta gcctaatttc atgggtatct ccaaaacccg atccaggccg
     5101 ctcaaccgag tcaggtgatg tccgaatgtc atcggcagca ttccgggtat gagcactttc
     5161 acacaacgca gcccattgcg acgcgtctca cttgacgact gatcaattac aatcacatcc
     5221 atctgaagac ggcggaatat ttgaagaacc tgccttaaat catccgttaa atcttcatgg
     5281 gcagggacag agggaaactc ttcagcgaat gtacataaag gccgggaatc ttccaataaa
     5341 aaatggagcc ttctctccgc ttgcggcaaa ctgtacagca gtgaatgatc ttccatatac
     5401 tgtacaagtt ccgaatcgcc aaacatcgct tcggcttcca gcctccgctc ctcccatcgc
     5461 ctttcgaccg tcgggatcat cactgccagc tcgtgtatag cactcttagc cgcttgaacc
     5521 gggtcaagat gagctcccgc agcacagagc aggtttacac actgctccgt ccctcccttt
     5581 gcaagtgccc atatgctcgg aattccgttc tccatcgtca tattgtacaa acttacctca
     5641 tatccagtaa ccgcccttaa acgctggatc atcagcacca gttccgaatc tcccgacgat
     5701 atataatcaa gccgcgaaac atgtagctgt gcataccagg ttatcaaaaa agcatctctc
     5761 tccactactt cgaaaatacc gtgtaaaaca gcttcctcta tactgtttcc taccgcgcat
     5821 ccattggagg tttcatagac gaaaccaccg ccgccaccga ggctgtaata agccaacaga
     5881 tgggggatca agacgggacg ctcctctaaa aacgaatagc cccataccca ttccatgggg
     5941 gcatccggat caaacgggat gaatggaaaa tcaggctgct cgtatcgccc ctctgcatga
     6001 agacccaccg tagacggatc tatcgcagct cccttaaatt gggaataact gccatgcata
     6061 accgttcttt taccgcgcac agctacaccg caataacgct ccagcccctc taatatgcca
     6121 gcaagttcgc tatccaaaaa ggaatgcgaa cgtccccccg ttatttcatc gtaaaagccc
     6181 aagggaagat taatggccgc gccggcaaag gatgaagata gactccactt cttatcatta
     6241 aaaactccag tgcgactatc ccagtaatct cttaacagaa cccgctgtaa atcactcatc
     6301 gcacgacagc ggtaggtgtt gttgactttt aggcacttct gcagcgatat ttttgctaac
     6361 tccggtgaat catccggcaa ttgaccgcaa accgagcaag tccccacggg tagaacataa
     6421 tggattgtgc tgctcaaatt tttcaaatcg atcaaataaa catgttcttc cgtattcgct
     6481 ttatcgcctc gcagcacctt agtcacttct gccgcgatta tatgtgccag ataaccagat
     6541 cccgctggag ataattcagc agtataatta ggagcataat caggagatac cagcttcatc
     6601 agcatctcgt ccacctcttg gcgattgctc cccgccaatg ctagccttgt ctcagcgcat
     6661 tggaagcatc caaacttccc cggatgaatc agtggtccta ccactccttc acctaatgat
     6721 atatatgcgc ataaccatgg ggttccacgc ggccgcaata cctgttcagc ttcaagataa
     6781 atagatgagc tatcctgttc ctcaagtacc aataccagat ccgtgacggg tatggtttca
     6841 ctgaaatctt ttctgcgcac tggcaggaat tcggacattc gcttataaac ggcgtctgcc
     6901 agtattccct ctccaacaat aacgacagaa ttcaatagac tcccccctct tcgaggctga
     6961 ctccataaat ttcaaacggg cttttgcccc acaaagattt gctcggcata ttgaacactt
     7021 cgaggcgctt atgatgctgc ttcagcgttc gaacggccga ttgcattaaa gatccgtaat
     7081 ctagcgaacc gctatcggga actggggttt cctgccattc attattcctc caagtaaccg
     7141 cagaaatcga agcagcttcc ctctgatcca acgctttctg cagggattgg cggagggcaa
     7201 gagtaaagct gagatccgcg ctgacatacc acgaagagcc ccgatttacc catacgaccg
     7261 gaaaaccaag taaaggttca ccgacggcga taactggctc accctctatg atgcttaacg
     7321 cttgtaaata atattgacat cgcacatctt taatttgtgt acacgctatg cgtagaactg
     7381 tcggctcatg agacagcgtt cgtttgccga actctttagc taaacaagct ctaaaacccc
     7441 gcccaacggc ttcggccaaa tcgcaccctg ctccaatatt gatttcttgc tgctgatgtg
     7501 agggcaacca ggagaacatt aagggaatca tccgagcagc atacgcttca agccccgcaa
     7561 gtccagattc tcgccgtgcc tcttcatgcg ttagcccgct ccggatgatc accgggagaa
     7621 gaggcgcagg ttcttccgat aacagatcca cgggttgaac aagacactgc gccagcggca
     7681 gctggattaa atccgcctcc tcccatgcat ggaaaatgcc tgttatcgta gaagtcagct
     7741 ggttcaacgc tgaaaaccac ttctgtggat ttgcccgctc attattgtcc ccaaaatgac
     7801 gctctatgtt ctccaccggc cgagcagcct catatccgaa cactagagga tgaggaagca
     7861 cctggtgcca gcctccggtc aacgtaaccg gatcaagtaa aaagcaatga ttccagctat
     7921 acgcatcatt ctcggccgta attgctttat gccattcatg cacgagtaga ttcgatagta
     7981 agcctgctgc tgcgacagag aggccttttt cacaacggct ttcaggaaag acggacgaat
     8041 ggatgcgccg ccaagccgac tcccatcgtc cgtttccatc acaattcagc agaggaccag
     8101 ccattcccat gcctctgacc aagatcccgg ggagcatctg tctcctttct gctatacagg
     8161 cattctgaag cttcagaagt tcatctaaac ccccgtgctc cgacacatac agaataaatt
     8221 gaaacggtcg aacaatcgcc ctccaattca gatcctcatc tcttgcagca gcaataattt
     8281 ttaacgaggt ctcggcctca cggccataag catgttcgca aaattccttg agtttgcccg
     8341 tgtctatcgg ctccttgctt gttacataaa ccgtgagctt ggacaaaccg aattcatacc
     8401 atgattcagc aagcgagagc aggattggac cggaaccgat gacgagcgtg ccttcctcca
     8461 gtagagacat ctcgcacaac tcctttccca acttttcaca tcttaaatga accattcagg
     8521 ctgattaagc ttctcccgag cgttaaaatt cattttaaga tatgtgtccc actccctttc
     8581 tatgactgat caataattac tccaaatctt ccatattgct cgtcagagca gaggtaactg
     8641 aatgacaaac gcttttcctc tctcgccttc tgaacttata taaatgcttc cttgatggat
     8701 atccacgatt ttcttgacga tggataaacc taagccattg ccctctatat ttcgacctct
     8761 tgcccgatcc gctttgaaaa accgactgaa tatccgctct ttatcttcat cggcaatgag
     8821 gaggccatca tcataaaagc ggatctccac ttggtcttgg tcggccttca gttcaattgc
     8881 aattctcccg ccggcagaag caaacttaat tgcatttgac atgagattga tccatacctg
     8941 acttagaagt tcttcatccg cgtgaatcat cgtacgctcc cctttcatct ccacctccag
     9001 ctgtttttcc gaccagaggg cttcaaaagt gagaaccgta cgccggattt gttcagcaag
     9061 atcgaaatgg gttggagcca tcacatgcct ttccgactcc aatgcggcca aacggagtaa
     9121 attttcgctt aaccgcgata agcgttcact ctcctgcatg ataatttgaa gggctcgcga
     9181 gcgctccggt gctttaagcg acccttcgag aagcatagcg gagaaacctt taaccagtgt
     9241 taacggagat tggaattcat gagaaacgtt agcgacaaac tcctgccgtt cacgatccaa
     9301 ttcccccaac tcagcagcca tatgatttat agccttggcc aatgttccca tctcatcgcg
     9361 ctgattctcg gacagcctta cattaaagtc accggttgcc aattgcttag cggcagcggt
     9421 taccgtctgt acaggggtaa ccaagcgcct tgcaaaaaat aagataataa gcccgcctac
     9481 caataggacg ataactaata tcactgtaat ttccgttaag cctgaggatt cactgaaagc
     9541 tgcctgtgca agttcgattt ggtaaacacc ttcatccagc ggccatggca ttgtgactga
     9601 aatatcacaa tcacagaagt tatctgcatc aggccagtta aatagttgga tctcctgaga
     9661 gtttggggca gtcaccttca atctgacgga agagagctga gctgcatttt ccagaaatgt
     9721 ctgttgatcc tccggttgag cttggctgta caattgtata agctgctgcc cttttcttgt
     9781 aagctccctc tcagtgtaac gttcggcgga atcctgaaat ataaagattg ctgcagccca
     9841 ggcgactata accccaatga gtactgcagc aagataatag aagacaattc gaacatatag
     9901 ggtcttaaac atgctttacc tccagcttgt acccgagtcc tctgacggtc acgatttcaa
     9961 agctgtccgt caactcagag aatctttctc ttagccgttt tacgtgtacg tctaccgtcc
    10021 gttcatcccc ttcaaagtca ctgccccata catgttcaat gatttgttca cgggtcaaag
    10081 tgcgattggg ctgggaggca agccgataca agagttcaaa ctctttagga ggtaatgata
    10141 cttctttctc acccacggac acttgtctct gggcattcaa atacaattgt ccgacttgaa
    10201 gagaatatcc gcggtcaaac cgatatcttc gcaaaagtgc tttcacccta tagcttagct
    10261 ccttagggtc aaaaggcttc accacgtaat catccgttcc tgcctgaaag cccgctacct
    10321 tgtcgatgtt cgttcccttc gcagtcagca taagcactgg gatgtcaaag taccgtttga
    10381 tttcgcggca cacttcgagc ccatccgtgc caggcatcat gatgtccaca atcacaagct
    10441 ccagtctctc ttcatgaata aaagcgatag cctctgtacc atttttcgct tccagaatgt
    10501 tgtaatcatc tgaccgcaat gcaagtctga ccagttcgcg aatgaaagga tcgtcatcta
    10561 ctactaatat ttttatcatc cggttctcct ctgccatttc acgcttattc cactaacttc
    10621 acatatttat ccttaacgta atcatcgaaa aactgcacta atttctcatt aatttcccca
    10681 agcagagata cgtcacggct gccaaataga ggcgagtaca gcgtgatatc agaaaagctc
    10741 atatggtcag ctccaggaac cacccattcg atcccgccat ttttcaaaat tccttccttt
    10801 ctttgaacga gctctgccgc ttccttcacg tattcctcct ttacggcgag tcctgggtac
    10861 ttatcaggat cagaccactc ttcctctaaa agctccagat tggcgaactc atcgctgtat
    10921 gtcgtttgaa tgtataagaa cggattgggc aggccgtctt cgatcacagc accatacgga
    10981 aatccgtcca tatttacgcc tgagctcaac cgagaatcct ggtgcatgac ctgtgctgcg
    11041 gctgcgcctc caaaagaatg gccaagcata cccagccgct gaagatccat cttcccggtt
    11101 aaaatatgct gggaatcctt ttcattcaga tcatacaatc tatcgagaac aaacttaaca
    11161 tcgtctaccc acagctgcat atgttcctcc atgctgtccc aaactgacga atcatcagcg
    11221 atgaccgctt tttctttggt gatccgtcca tcaggaaaca aagtcgggat ttccgtgtaa
    11281 tacggatgct cgatcgctac tacgatatat ccatggctcg ctaaattttc cgtcatactg
    11341 gtgtacatga agttggatgc tccaaaaccc ggagataaga gaagaacggg ataccccgcc
    11401 ttatccgatg agatcggtac ttgcagatag gaatgtgtcg ttatgtttat catagaatct
    11461 acgattgctt tcacatacaa tggttggcca tcgcttaatg acttcatctc ttcaacagaa
    11521 tgcgcataag gagcgggctt cataggatcg attgacttag caggatacca gactcgaacc
    11581 acaatctccc gtttatcgtc ctcttcagcc gtccaaggct ccgagcggct gtcatcaatc
    11641 cagtggtagt tgatcgtacc gatatcatga gatcccgttg gattcggcaa gacgattggc
    11701 ggcaatacat atagaggaat gacaagcgcg gctgccagcg tcaaggtgcc caagctcaaa
    11761 acggcgagcc gcttccataa ttttgatctt ccatgcattt taaccgttct tctaaataag
    11821 cccgatagaa tgaagcataa ccaaattact gcgaagagaa gatagaacaa tatcatttgt
    11881 accctatagc cttccagcag aacatgcaat ccaacggtca aaacgccaat accag
//
