LOCUS       NZ_LT732548            26393 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Paenibacillus bouchesdurhonensis strain Marseille-P3071T, whole
            genome shotgun sequence.
ACCESSION   NZ_LT732548
VERSION     NZ_LT732548.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus bouchesdurhonensis
  ORGANISM  Paenibacillus bouchesdurhonensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1
  CONSRTM   Urmite Genomes
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2017) URMITE, 27 Bd J Moulin, 13385 Marseille
            Cedex 05, France, 13385, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900155685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:11:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,206
            CDSs (total)                      :: 5,108
            Genes (coding)                    :: 5,019
            CDSs (with protein)               :: 5,019
            Genes (RNA)                       :: 98
            rRNAs                             :: 8, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 3, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 31 of 89
            Pseudo Genes (incomplete)         :: 75 of 89
            Pseudo Genes (internal stop)      :: 9 of 89
            Pseudo Genes (multiple problems)  :: 21 of 89
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:18:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3427359
            Orig. end                         :: 3453752
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT732548.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26393
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="10"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26393
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26393
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16393](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16393)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(877..1497)
                     /locus_tag="CZ379_RS19440"
     CDS             complement(877..1497)
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006211351.1"
                     /locus_tag="CZ379_RS19440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonuclease HII"
                     /protein_id="WP_110933133.1"
                     /transl_table=11
                     /translation="MSDLLTYEKEYWQRSFQHIAGIDEVGRGCLFGDVVAAAVILPHGL
                     ILEEVNDSKKLTAKKRERLYDIIMKEALAVSTGFVDAEAIDRLNIKQATRLAMKQAVEQ
                     LVIRPDVLLVDAEKIDVGIEQMAVIKGDAVSQSIAAASIVAKVTRDRLCEGEWDVLYPE
                     YGIATHKGYATKLHRERIQALGPTPMHRKSFMRNLFVQEQTLF"
     gene            complement(1683..2657)
                     /locus_tag="CZ379_RS19445"
     CDS             complement(1683..2657)
                     /EC_number="2.7.8.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_4"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018751011.1"
                     /locus_tag="CZ379_RS19445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MraY family glycosyltransferase"
                     /protein_id="WP_199925841.1"
                     /sec_met_domain="Glycos_transf_4 (E-value: 7.1e-40,
                     bitscore: 134.6, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVLIILYVISFIMSFLIVYLLIPPFGRLAFRLDFVDKPRKDVER
                     KLHREPIPLTASYVIFIGFFVTYLIVGREYNLETAAIFIGGILLLVIGTLDDWYKTKGK
                     DFPALPKLIVQVSAAVIVYASGISFTGFFNPISGEYVVLPGILQFILTILWIFGVTTVI
                     NFSDGLDGLAGGLSAISAITLFIVAVTKGQSNSAIMAMILVGVALAYLRYNKPPAKIFM
                     GDAGATFLGFILAVIALDGAFKQATVLSLFIPVLALGVPIFDNIFVVVKRFLQGKSIYE
                     ADASQVHYRLLRAGLSHRQTVMFLWLISTCLCLSSIILLLIQT"
     misc_feature    2728..2741
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.07"
                     /tool="antismash"
     gene            complement(2795..3658)
                     /gene="ylqF"
                     /locus_tag="CZ379_RS19450"
     CDS             complement(2795..3658)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ylqF"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015736353.1"
                     /locus_tag="CZ379_RS19450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="WP_110933134.1"
                     /transl_table=11
                     /translation="MTIQWFPGHMTRARRQIQEKLKLIDVVIELLDARLPLSSRNPMID
                     EILQGKPRLILLNKADLADPAITREWIDYFEKEGFAAIAVDASSGQGVKEIPALAKELL
                     KDKIEKQLAKGMNPRSIRALIVGIPNVGKSTLINRMAGRNIAATGDRPGITKGQQWIKV
                     GTEMELLDTPGILWPKFEDQNVGYRLAVTGAIREEILNIEDIAFFAVKYLAKYYWQPFA
                     ERFEMEEAPEDFENPDEIVAVMEAVGRKRGCLMSGGRVDLEKASSVLLRELRAGKLGRY
                     SLEAPY"
     gene            complement(3699..4322)
                     /gene="lepB"
                     /locus_tag="CZ379_RS19455"
     CDS             complement(3699..4322)
                     /EC_number="3.4.21.89"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lepB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638101.1"
                     /locus_tag="CZ379_RS19455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="signal peptidase I"
                     /protein_id="WP_110933135.1"
                     /transl_table=11
                     /translation="MEQQFQSETGQTGLPEDPPSKEKNEALEWLKAIVIAVVLVLLIRW
                     LLFAPFIVDGESMQPNFHTSERIIVNKIIYDIRAPKHGEVVVFHVPSQGRDFIKRVIGI
                     PGDTVQVEGDTLMVNGEVVDETYIKDVVTEKHNNNQLYNTEGNFPNEFVQESTVPEGHI
                     FVLGDNRSNSTDSRRIGFVPYKDIVGRADLVFWPLPDIKAIKHK"
     gene            complement(4431..4775)
                     /gene="rplS"
                     /locus_tag="CZ379_RS19460"
     CDS             complement(4431..4775)
                     /GO_component="GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019910375.1"
                     /locus_tag="CZ379_RS19460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="50S ribosomal protein L19"
                     /protein_id="WP_110933136.1"
                     /transl_table=11
                     /translation="MNIVQAITQEQLRKDIPSFRAGDTLKVHVKVIEGTRERIQLFEGV
                     VIKRRGGGISETFTVRKISNGVGVERTFPLHSPKLDKIEVARRGKVRRAKLYYLRELRG
                     KAARIKEARR"
     gene            complement(5018..5140)
                     /locus_tag="CZ379_RS26995"
     CDS             complement(5018..5140)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS26995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267890500.1"
                     /transl_table=11
                     /translation="MEKRNAISVLIKWVGILEIVVGVIIGLNQDIPLYWIIGSV"
     gene            complement(5189..5986)
                     /locus_tag="CZ379_RS19465"
     CDS             complement(5189..5986)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS19465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_110933137.1"
                     /transl_table=11
                     /translation="MKFLGLGCLGMLLFATLVIIGISTESGFLVVIGLAGIGFSAFKGL
                     SLDKKEEEDLKSEVEQMALKSLEKDGDFTPSQKFLAEDGETCIAIDETRKKVCILENEY
                     DNTGKTLIKGLSKYSFRKKVFDYKDIFQAQIIIAEDSKTRIYRSTIETEEEVSGIQLQI
                     VVNDTKKSFYRITFGDYPESIRKYSPLFQDNYKNAMHWKNILNYIIMDSDDSEDEHVQD
                     AVVELNKPDHSTADELIKLSNLLKEGFITREEFDKQKNKLINS"
     tRNA            complement(6182..6260)
                     /anticodon=(pos:complement(3433582..3433584),aa:Pro,
                     seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CZ379_RS19470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Pro"
     gene            complement(6182..6260)
                     /locus_tag="CZ379_RS19470"
     gene            complement(6570..6698)
                     /locus_tag="CZ379_RS27000"
     CDS             complement(6570..6698)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS27000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267890501.1"
                     /transl_table=11
                     /translation="MEQTEKNESKQSQDNGRREDDRMLTVDDILDFYAGGRKKLLQ"
     gene            6961..7869
                     /locus_tag="CZ379_RS19475"
     CDS             6961..7869
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009222981.1"
                     /locus_tag="CZ379_RS19475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_110933138.1"
                     /transl_table=11
                     /translation="MSRFKKYALISLAFMIILYAVAVANPGTVLSRKACSSWSLVKDQA
                     FLMTHPKLDGSLKLPANFTIQPGTAEQVPVLMYHYITPKAYNDQPDNNSIMNLEDFEAG
                     IDYLYEQGYYTATMEELEQYVLGKATLPAKSVVITFDDGYQNNYTYAYPILKKYGFHAA
                     IFLIGSRVQTETSVFDPAKKSFLSQEEIEASSDVFEYHSHTYDLHHKGFMKCGLNYASG
                     FDTTSLESDIAKMKELGIDSPYFAYPYGEKSTPMVYYLQKNNYRMAMTVHQGFVKPGDS
                     PMRLKRLTVTSATNMADLLQP"
     gene            complement(7950..9341)
                     /locus_tag="CZ379_RS19480"
     CDS             complement(7950..9341)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020754735.1"
                     /locus_tag="CZ379_RS19480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_110933139.1"
                     /transl_table=11
                     /translation="MRHKTLKRDFYLLVVKVVSFTIVSTIVAYLLLVIFLFSDTAKPTD
                     YYVKYFNIIERMVENNPEGVLLGELPDLTGMSDQIKSEVLDTSGHHLYGELGIGNPSVD
                     LWKNLNKEIVRNNYVYRYIPIVKDDALQGVYLLKAPFGYVVNNYKDQPVSVFLYIALIM
                     SPIFFFMLYLVLFTKQLYEKMSRNITSLLQGAEHISTGDFDFRINELEGKEFNVIQQSF
                     NGMVSSLKEADLALQKMELERSMMVQSIAHDIRTPITVIKGQLELITQLQNSSAFTFDA
                     FKQTIDSNCNKMINLTNNLAVLYKVEKVDFMLHPEQVHLEDTLLEKKKEFSAMAQLKGI
                     SIRFEIQLTKLVYWIDEAMLIRVLDNILYNSLRFTSHGVIKLEVHDDPEKNRIHFCCTD
                     TGMGFKQQDTKALFEAMYQEDYYKDHFGLGLYIAKRIVSNFKGEIRASNSPQGGAVIQF
                     YIEEC"
     gene            complement(9331..9978)
                     /locus_tag="CZ379_RS19485"
     CDS             complement(9331..9978)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013522847.1"
                     /locus_tag="CZ379_RS19485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_234404958.1"
                     /transl_table=11
                     /translation="MIQQYLELYAFRVTAVSSGEQALKAVLHHHYDIIILDVMMPDLDG
                     VALCEMIREKVICPIVFLSAKTLEEDKIKALSSGGDDYIEKPFSLAELKARIECHIRRD
                     ERIRDKGTSKVSSGRLVVDLDAKILTCNGMPIHLTKKEYQIVEFMILHKGRVFTKEDIF
                     ERIWGHESQSYYDTVTESIKNIRKKIREHDSDYAYIKTLYGLGYRWEVQHET"
     gene            complement(10001..11347)
                     /locus_tag="CZ379_RS19490"
     CDS             complement(10001..11347)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014194793.1"
                     /locus_tag="CZ379_RS19490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_110933141.1"
                     /sec_met_domain="LANC_like (E-value: 2.5e-70, bitscore:
                     235.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHEQIDYIVKSIGRKLSDYDYLRQVSNEESNYLETESGLINPFQE
                     LSLSHGLPSLCMLYGEMNEHYPEEGWDRIGHQYMQRIGQQLEEEGVQSLSMFTGAAGIG
                     LSALCISKQRRRYSSFISSINELIANSIDPLLEQIQSRQDLHMQDYDPISGVTGVAAYT
                     LLFHNDSNFPVMKEINRKIVNYIIHVCQDKECNGKLVPGWYISAANQFSEVDKLRWPNG
                     CFNIGLAHGIPSLLITLCDSYLKGIKEEGQLDSIRKLADFLLQSRIESEGQYYWGTHIS
                     IEEYNDLTVTSTYTRDAWCYGTPGVAYSLLAAGKALQDDKYLTPAVESMKRAAVRQQEI
                     YCPTFCHGLSNLAMISKHFYSVTKDAEFLQITSSLTEQMMSYYNEELPFGFQTVDKKTG
                     IEKLYDYVGLIDGVTGVALTLLAVNKDKKTPWDSAFLLGGLSDEEHTRC"
     gene            complement(11340..13196)
                     /locus_tag="CZ379_RS19495"
     CDS             complement(11340..13196)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011229812.1"
                     /locus_tag="CZ379_RS19495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_110933142.1"
                     /transl_table=11
                     /translation="MNKKTLNDTDTVDDRVSFRDIRETMKLLPKTLRLVAASDKRNFFM
                     ISLLSLLVGFSPILTLFGSQHLLNMLVTGTFQAVVWAFGIYIVLHLYSDVINSIKSFYE
                     QKFETILRFKINYSVMEKCSKLTLAHLEDAAVYDKLQRVQSEVAYRPFQIFQAIISMIT
                     AFITLISSIIILLNWKPWVLLILIVIPVLLSTYFFRIGQREYNVEWNRTSERRKSWYLT
                     YLLTKDVTFKEVKLYGISRYVLSKFENINKKFIKQDIALFKRRTVFTVLFDFIEQICTN
                     VVLFIIIYSAYLGEILIGNVVGFIKALSLIQSNSKLIINTIYTLYQSNLYMSQLFDFLA
                     LEEAGESVDTLETPAAADNTISRIETIKISDLTFAYPSFAHPVLNNINLEFRRGERIAI
                     VGTNGSGKSTLVKLLIKMYQIDDDMIQFNNKSINSYRTEQLQSCITVLFQDFVKYELTL
                     RENVGFGQIDRMHEEEAISEALFKGKVDFENDLDTQLGLWFDEGKQLSGGQWQKVAIAR
                     SFFRDASLYILDEPSSALDPMAEKQIIDMFLQMTKDKIGIFISHRLSTAMLADRIVVMH
                     KGEVIGIGEHQELLKSVSLYREMYELEQSKISGYRKEEFVDA"
     gene            complement(13223..16393)
                     /locus_tag="CZ379_RS19500"
     CDS             complement(13223..16393)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="CZ379_RS19500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_110933143.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.7e-145,
                     bitscore: 481.9, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.6e-15,
                     bitscore: 54.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.6e-35, bitscore:
                     120.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVQQWFQDTGTFMIRSAILPLSRYYHFFNEGISEDEAEEYIKKWS
                     ENSVFRESILVASKNLYETMDLFSKGEILKKKEHFMNSLYKYLIRMSTRPTPFGLFAGV
                     GFGEFTKESTALLGSRKYTKKARPDLEWLMKLVRKIETDYTEALCYSNNKCSFVKGNRV
                     VLPHSTLKETDTRSIQEVNIRATKAYHIVYEAAAESASFSQLVKALEQHYPEIEQHVFQ
                     HFLQELIEKEYLISNIRPPLTVIDQLDYVIKQLTERLGDAELLIKLKEIQSKIDAYNCT
                     ALGAGEENYLELHRLMTEVMESKSPLQVDLSLQGDEPIRLNGYILQEVNHLINKLLGFL
                     RPPDETGLSLNKYRQDFIEKYGQNREVPLLEMIDGDRGIGAPSGYTNPPSMRVEQSSSV
                     TPYFHEKVQAYFWNKYLEALTHGSSCIEIQEEDILALSLPSCPYEELPDSFEINLIFAD
                     KNNLDEPLYYVGPNVGSTKAGKSFGRFAHVMDSPEKFFDRLHELNQGLIDREEYIGCEV
                     SYLPNELRNANVTRNIHGNKYELALFTNSSREPFYSLTLNDILIGVEGTSFYAKSKRLN
                     KKIIFHFNNMLNPQISPNAVRFLYDISLEDERKWYNFPWEVIFRDLPYTPMIKYRNFVL
                     APEKWVLNSSTIKLDKRQGFKRFMELFTGYRHSRNIPKYAYIASGDNRIIMNLDDQKCL
                     KILYHEFVNNGNNVMLTAVEDFLEKAWGGDMDGHAQEIVIPMIKMAQEAVENPKAAYPE
                     ERFNGISSTSPDRLKLPFEEWIYLKLYGTQSREEELISVEIADYCAELINQERVKGHFY
                     LRYADPNPHVRLRIRGDQQQLLEAYPDIQLWLRSLIEKGLISHFVLDCYDREIERYGGL
                     FFMEAAEQVFCQDSVTVEKLIKARKDKLIDWSDEIVGVAATICYMEQWGWDYSMQLEFL
                     SSQVKPSDYRDDFKRVRSQLINVCHSMNQMEALQTDSQEASLFNLLNERFSAVRSYSAQ
                     INSNLSRLSTHPWAIVDSLIHMHCNRLFGIDRELEKKLRALTCHTLYVLKHQQIHLTKV
                     QQNAQVYK"
     aSDomain        complement(15671..15928)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CZ379_RS19500_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.40E-17"
                     /identifier="RREFam001.1"
                     /label="CZ379_RS19500"
                     /locus_tag="CZ379_RS19500"
                     /protein_end="241"
                     /protein_start="155"
                     /score="54.4"
                     /tool="antismash"
                     /translation="SFVKGNRVVLPHSTLKETDTRSIQEVNIRATKAYHIVYEAAAESA
                     SFSQLVKALEQHYPEIEQHVFQHFLQELIEKEYLISNIRPP"
     gene            complement(16502..16669)
                     /locus_tag="CZ379_RS19505"
     CDS             complement(16502..16669)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_a"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881441.1"
                     /locus_tag="CZ379_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_110933144.1"
                     /sec_met_domain="TIGR03731 (E-value: 6e-17, bitscore: 59.4,
                     seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_a (E-value: 1e-05, bitscore: 22.7,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKLDDFELDVQIKTSVSKVEPQITSKSLCTPGCITGVLMCFTKG
                     CEISHSCVKC"
     CDS_motif       complement(16601..16669)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKLDDFELDVQIKTSVSKVEPQ"
                     /locus_tag="CZ379_RS19505_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16502..16600)
                     /prepeptide="core"
                     /locus_tag="CZ379_RS19505_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="10.20"
                     /molecular_weight="3206.9"
                     /monoisotopic_mass="3204.6"
                     /core_sequence="ITSKSLCTPGCITGVLMCFTKGCEISHSCVKC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKLDDFELDVQIKTSVSKVEPQ"
                     /leader_location="[16600:16669](-)"
                     /alternative_weights="3224.9"
                     /alternative_weights="3242.9"
     misc_feature    complement(16772..16792)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.8"
                     /tool="antismash"
     misc_feature    16816..16832
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 25.82"
                     /tool="antismash"
     gene            complement(16860..17681)
                     /locus_tag="CZ379_RS19510"
     CDS             complement(16860..17681)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.5"
                     /locus_tag="CZ379_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_110933145.1"
                     /transl_table=11
                     /translation="MSGIFQSELYRFLHRKTFYIFTILIVISTLLLSLGFSAVNQEGDS
                     MLAKSMLAAINYQSNEGPILQNADRLTLPHAVLSNLDIFLVFIVLPVISSLLIGDDRAS
                     GSLRMVLTRPISGGRLLLGKLAVLVLCNLFFIFVIFIVSQVSAFIFMPSVDSTTLVSNQ
                     STLTAMQSLRFNLLYYLIYFAKILLISFIFSLISTCIKNTAVAVVADIAVLIAGMYLSA
                     FLLDFLFSALTFIYDIITGHEPLLSLFYILLLSVALILTLSIRWSKMNYQD"
     gene            complement(17706..18536)
                     /locus_tag="CZ379_RS19515"
     CDS             complement(17706..18536)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.5"
                     /locus_tag="CZ379_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_199925687.1"
                     /transl_table=11
                     /translation="MALLKYEGYKFFRRKVMWLSFLAVPFLIALSYLYLSKNNITLSAI
                     APEDPSFASQISFPYLVIQEQLMLVFNGLVIFYTAIVITEERRSGELRQVIARGYTMWK
                     VLASKMLLLAIVFFILFVECLGLSWIAGYLLMPKVDYAYTFFSYVPIRGLSALSYTIKY
                     YGLAFLSVLGMLSLMTWVSILAKNKIITAGIGIGILIISMIYTQVISILYELGILRIDV
                     LLYASIVQIQFTGIASVLGGIQGLTKDIAIVFAIYLIVFNVLAFWHERVSDYTD"
     gene            complement(18541..19272)
                     /locus_tag="CZ379_RS19520"
     CDS             complement(18541..19272)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312511.1"
                     /locus_tag="CZ379_RS19520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_110933147.1"
                     /transl_table=11
                     /translation="MTHLIEVNNVSKVLSRRRVLDAVSFNVPKFSITGFIGPNGAGKTT
                     LIRILTGLISFQGDVKLNRVPISNKTEALREVGAMVETPVFSLYMTGYQNLYALAMLDS
                     SMSKQERKKRIAEVLELVGLTGREHHKVKGYSLGMKQRLGIAQALLNHPDLLILDEPTN
                     GLDPMGIKEIRDIILKLNRERGVTIFVSSHLLGELEKICDHFIVIQEGKIVKQGSKESI
                     LIEGGTEHLEDAFLQLMFGGQ"
     misc_feature    19317..19330
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.01"
                     /tool="antismash"
     misc_feature    complement(19320..19333)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.24"
                     /tool="antismash"
     gene            complement(19418..20167)
                     /gene="trmD"
                     /locus_tag="CZ379_RS19525"
     CDS             complement(19418..20167)
                     /EC_number="2.1.1.228"
                     /GO_function="GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="trmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638106.1"
                     /locus_tag="CZ379_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="WP_110933148.1"
                     /transl_table=11
                     /translation="MKVDVLTLFPEMFSGVFGTSILGKAQDKGIVSLKPVNFRDYAGNK
                     HGTVDDTPYGGGGGMVLKPDPIFRAVEDLLSVQPANAPAPRIILMCPQGESFSQRKAEE
                     LAKEEHLIFICGHYEGYDERIREHLVTDELSIGDYVLTGGELPAMVVIDSVVRLLPGVL
                     GNETSAISDSFSTGLLEYPHYTRPVEFRGWKVPDILLSGHHANVADWRRKEALRRTWLR
                     RPDLLEHIELTPKDRKWLQEIQAEQGE"
     gene            complement(20170..20688)
                     /gene="rimM"
                     /locus_tag="CZ379_RS19530"
     CDS             complement(20170..20688)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rimM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006676645.1"
                     /locus_tag="CZ379_RS19530"
                     /note="Essential for efficient processing of 16S rRNA;
                     Essential for efficient processing of 16S rRNA; Essential
                     for efficient processing of 16S rRNA; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="ribosome maturation factor RimM"
                     /protein_id="WP_110933149.1"
                     /transl_table=11
                     /translation="MSDSLLSVGKIVNTHGIRGELKVLSSTDFPEVRFAPKSKLIIVHP
                     ETGEQLEVTVASARPNKGMFIVRFAGYDNINEVEKYKGFDIKVSKGASVGLPDNEYYFY
                     EIIGCRVIDEEGKELGVIEEILRPGANDVWVVKMPSRKQLLLPVIDEVVLDVDVEAKIV
                     KVHLMEGLL"
     gene            complement(20804..21034)
                     /locus_tag="CZ379_RS19535"
     CDS             complement(20804..21034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007132100.1"
                     /locus_tag="CZ379_RS19535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="KH domain-containing protein"
                     /protein_id="WP_019638108.1"
                     /transl_table=11
                     /translation="MEQLVGVIAKALVDHPDDVRVEVVEKEHLIVYELSVHPDDVGKVI
                     GKQGRIAKALRTVVASAAVKMDKRVTVDIIS"
     misc_feature    21019..21033
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.85"
                     /tool="antismash"
     gene            complement(21058..21330)
                     /gene="rpsP"
                     /locus_tag="CZ379_RS19540"
     CDS             complement(21058..21330)
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281051.1"
                     /locus_tag="CZ379_RS19540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S16"
                     /protein_id="WP_110933150.1"
                     /transl_table=11
                     /translation="MAARIRLKRMGAHKAPFYRIVVSDSRSPRDGRFIEEIGYYNPVAE
                     PAVVNIDEEKALNWLQNGAQASDTVRNLLSKAGVMKKFHELKQQK"
     gene            complement(21377..22756)
                     /gene="ffh"
                     /locus_tag="CZ379_RS19545"
     CDS             complement(21377..22756)
                     /GO_component="GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005048 - signal sequence binding
                     [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="ffh"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309861.1"
                     /locus_tag="CZ379_RS19545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="signal recognition particle protein"
                     /protein_id="WP_110933151.1"
                     /transl_table=11
                     /translation="MAFEGLTSRLQGVFSKLRGKGKVSEDDVNEAMREVRLALLEADVN
                     FKVVKEFISKVKEKAVGKEVMDSFTPGMVIIDIVNKELTDLMGGSQAKLAKSNRPPTVV
                     MMAGLQGAGKTTTSAKLAKLLLKGNHRPLLVAGDIYRPAAIKQLQVLGEQIKVPVFSLP
                     EGNSPVEIARQALQHAKDNGNDYLLIDTAGRLHVDEELMEELRQIHEITQPDEVLLVVD
                     AMTGQDAVNVAESFNQQLQLTGVVLTKLDGDTRGGAALSVKAVTGCPIKFAALGEKIDA
                     LEPFHPERMASRILGMGDMLSLIEKAQSNIDADKAKEMERKMRNAEFTFDDFLEQMDQV
                     KKLGPIDQIMDMIPGMGKMKQMKDIKVDEKQMGRVEAIVHSMTKEEKQNPDMINHSRRK
                     RIAAGSGTTLADVNRLIKQFDEMRRMMKQFSDMMGPKGKGSKLMKQMQGKAGKGMRFPF
                     R"
     gene            complement(22819..23172)
                     /locus_tag="CZ379_RS19550"
     CDS             complement(22819..23172)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009222975.1"
                     /locus_tag="CZ379_RS19550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative DNA-binding protein"
                     /protein_id="WP_110933152.1"
                     /transl_table=11
                     /translation="MSQENRLEKTNRINLLFDFYETLLTEKQQTFLKYYFHDDFSLGEI
                     AAEFGISRQAVYEHIKRAEGMLEVYEEKLGLLHKHEELSTVLVRLGELIADSELSAVHK
                     ERARSLLDQAEQL"
     misc_feature    complement(23286..23299)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.5"
                     /tool="antismash"
     gene            complement(23385..24032)
                     /locus_tag="CZ379_RS19555"
     CDS             complement(23385..24032)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015736361.1"
                     /locus_tag="CZ379_RS19555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hemolysin III family protein"
                     /protein_id="WP_110933153.1"
                     /transl_table=11
                     /translation="MANTHTYPRREEIANAITHGIGTVLSVAALVLLIVFSSLKGTAWH
                     VVSFTIYGVSMLLLYVCSTLVHSFKEGKVKDLFEIFDHSSIYLYIAGTYTPFLLVAIRG
                     PLGWSLFGVIWGIALLGVLFKAFFVKRFLFMSTFFYLIMGWLIVIAWGPLTAAVPFQGI
                     ALLVAGGILYSLGTVFYVWRAFPYHHAIWHLFVLAGSVTHFFAILLYLLPKW"
     gene            complement(24074..25087)
                     /gene="ftsY"
                     /locus_tag="CZ379_RS19560"
     CDS             complement(24074..25087)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005047 - signal recognition particle
                     binding [Evidence IEA]"
                     /GO_process="GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016819275.1"
                     /locus_tag="CZ379_RS19560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="signal recognition particle-docking protein FtsY"
                     /protein_id="WP_110933154.1"
                     /transl_table=11
                     /translation="MSFFKKLKDSIASKTETVTKQFKDGLEKSRKGFVEKVTDLVIRRK
                     KIDEEFFEELEEILIGADVGVNTVITLIDDLRSEVKKRRIEDAAELQPILSEKLTELLR
                     GDEDNAMKLNPHGISVILFVGVNGVGKTTTIGKLAHHYKQQGKKVLLAAGDTFRAGAIE
                     QLEVWGERVGVDVVKQQPGSDPAAVMFDAVQAAKQRGVDILLCDTAGRLQNKSNLMEEL
                     NKIYRVIQREIPDAPHEVLMVLDATTGQNALSQAKLFGEKSGVTGLVLTKLDGTAKGGI
                     VIAIRQELSLPVKFVGLGEKIDDLQRFDSEQFVHGLFAGLIQEEEAAEEDYTASQD"
     misc_feature    25069..25082
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.67"
                     /tool="antismash"
     misc_feature    25943..25958
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.67"
                     /tool="antismash"
ORIGIN
        1 tgccctcctt gcgccatctg tgcagcggtt tggcctgccg ccaaattgac cgctgatcca
       61 cttgatgaaa ccgtagtcga agctagggca gcatggaccg gaagcgaagc tgcgctcgct
      121 agattaggcg acgtttgacc cgcctgtgcc tgagtttgtg acgacactgt cgcatttgca
      181 gccccttccc tggcacccat tccgctggct gaacgactca tattccccag catttcttcc
      241 agcgtagaaa gcagttcatg aagaggcgcg ccaaatattg tctgatgcag actggcaacc
      301 gtctcccccg tgagcggaag gccacgtccc aacgcgatcc ctgctgtctg aatccattcc
      361 gataaaggaa cagatgcggg tttatgtaag gttaactgct gtaagctttg cagactctct
      421 ttggtcagcg gcaaaccgct tgtcctcatc atctgcacta gctcccgatt ggctgccgta
      481 tcctccagtc ccatgtccgc cagtacacca gccagcaacg cagcagacat cggagcggag
      541 gaatttgagc tgacaggctt caatacagcc aaaccatcgg ctgacggctg ctgtacctgc
      601 agcagtgtcg tttctccttg acgcagcgga gtttctaaag cagcgtgaag cttcacgcct
      661 tgcacctgaa tcaccgcttc ctgtccattc tctgagacac tcagcacagt tcctcttacc
      721 acctgtccgg tttttagttc taaggcccgc ggctctcccg gccgggaatc ccccataaga
      781 ctgcgcagca gcggtccgat attcatgagt atcctcctgt aattccatca atggtacgga
      841 aaacccgcct tgctaaagac gggtcaatga agaacattaa aacaacgtct gttcctgaac
      901 gaataaattg cgcataaaac tcttgcgatg catgggtgtc ggccctaggg cttgtatacg
      961 ctcccgatga agcttggttg catatccctt atgagtagcg atgccgtatt ccgggtacag
     1021 cacatcccac tcgccttcgc aaagccgatc ccgcgtcact ttggccacaa tggaagctgc
     1081 ggctatagac tgacttacgg catctccctt aatgacggcc atttgctcga tgcccacatc
     1141 gattttctcc gcatcgacga gcagtacatc cggtctgatc accagctgtt ctacagcctg
     1201 tttcatagca aggcgcgttg cctgtttaat attgagccga tcaatcgcct ctgcatcgac
     1261 aaagccagtg cttacagcta acgcttcttt cataatgatg tcgtatagtc tttctcgctt
     1321 cttggcggtc agctttttcg aatcattgac ttcctctaag attaatccat gcggcaaaat
     1381 gactgccgca gcaacaacgt cgccaaacaa acaacctcgt cccacttcgt caattcccgc
     1441 gatatgctga aacgagcgct gccagtattc tttttcatac gttaataaat cactcattgt
     1501 gcctccttgt tatttacaag cccaccgacc ccaacctgga aaattaaatc gatctaacaa
     1561 ctccgaatgc ccgctaacgc aagccctaca catggttata tcagtaatat cggaagctga
     1621 gcctgattta tatagacctt aaataaaata aagaccgggt cgcttacccg gccagacata
     1681 ctttaagttt gtataaggag caatatgatc gatgacaggc aaaggcatgt gctaattaac
     1741 caaagaaaca ttacggtttg ccgatggctc aggcctgcgc gaagcaagcg gtagtgcacc
     1801 tggctcgcat cagcctcata aattgatttt ccttgcaaga atcgtttgac tacgacaaaa
     1861 atattgtcaa aaatcggcac cccaagcgct aatacaggaa taaacagcga taagaccgta
     1921 gcttgcttaa aggcaccatc caacgcaata accgccaaaa taaagcctag aaacgttgct
     1981 cccgcatccc ccataaatat tttggcagga ggcttgttgt agcgcaagta ggccaatgcc
     2041 acgcccacta gaatcatagc catgatggct gaattggatt gacctttagt cacagccacg
     2101 atgaacagcg tgatcgcgga tatggcggat aatccgcctg ccagcccgtc caatccatcc
     2161 gagaaattaa ttaccgtggt tactccgaag atccacagaa tcgtcagtat aaactgcaat
     2221 attcccggca aaacaacgta ctccccggaa atcgggttaa aaaaacctgt aaaggaaatg
     2281 cctgaagcat atacgattac ggcagccgac acttgaacga tcagtttggg aagcgccgga
     2341 aaatccttgc ctttggtctt ataccaatcg tcaagcgtgc cgatgacgag gagcaatatt
     2401 cctccgatga agatcgctgc cgtttccagg ttgtactctc tgccgacaat caaatatgta
     2461 acaaagaaac caatgaagat gacgtagctg gcagtaagcg gaatcggttc acggtgcagc
     2521 tttcgttcga cgtccttccg gggtttatct acaaaatcaa gccgaaaggc caatcttccg
     2581 aatgggggga ttagcaaata tacgattaga aaagacataa taaacgaaat tacatataaa
     2641 atgatcaaca ccaccatcaa gtataatcaa caagattata caatcttacc ggaagattgt
     2701 cgatattctt ggtaacttgg aagacaaggc agcgcatttg ccgtatttgt caaaataacc
     2761 gtcttcccta aaggaagacg gttattgcat tgatttaata aggagcttcc agggaatatc
     2821 ttcctagctt accagctctc agctcacgca aaagcacgct tgaagccttc tccaggtcta
     2881 cccgcccgcc gctcatcaag cagcctcgtt tacggcctac agcctccata acggcaacaa
     2941 tctcatcggg attctcgaaa tcctccggag cctcttccat ttcaaagcgc tcggcaaatg
     3001 gctgccaata atatttcgcc aaatatttca ctgcaaaaaa agcaatatcc tcgatgttca
     3061 gtatctcttc acggatcgct ccggttactg ctagtcgata tcctacattc tgatcctcaa
     3121 attttggcca caatatccct ggcgtatcga gcagttccat ctcggtgcct actttgatcc
     3181 actgctgccc tttcgttatt cccggccgat ccccagtcgc tgcaatattt cgccctgcca
     3241 tccggttaat aagcgtcgat tttccaacgt tcggaattcc gacaatcagt gccctgatcg
     3301 acctcggatt cattccttta gccaactgct tctcgatctt atccttcagc agttccttag
     3361 ccaaagccgg aatttctttg acgccttgtc cgctcgaagc atctactgca atagcggcaa
     3421 agccctcttt ctcaaaataa tcgatccact cacgcgttat cgccgggtca gccaagtccg
     3481 ctttgttcag caggatgagc cgcggcttgc cctgcaatat ttcatcgatc atcggattgc
     3541 ggctagacag cggcaacctt gcgtccaaca gctctattac gacgtctatc agcttcaatt
     3601 tctcctgaat ctggcgacgt gctctcgtca tatgtccggg aaaccactgt atcgtcatgt
     3661 catcacctca gttcccgtta atcccttttg tcgggtcatc atttatgctt aatcgcttta
     3721 atatccggta aaggccagaa caccagatct gctcttccga cgatatcctt gtacggcaca
     3781 aagccgattc tccggctatc cgtgctgttg gagcgattat ctcctagcac gaagatatgt
     3841 ccctcaggaa ccgtactctc ctgaacaaac tcatttggga aatttccctc tgtattatag
     3901 agctgattat tgttatgttt ctcagttaca acatctttaa tgtacgtttc atcaactact
     3961 tccccgttca ccataagggt atcgccctca acctgtaccg tatctccggg aatgccaatc
     4021 acccgcttaa tgaaatcacg gccttgcgaa gggacgtgga agacgacaac ttcgccatgc
     4081 ttcggcgcac ggatgtcata aataatttta ttaacaatga ttctttcact cgtatggaag
     4141 ttcggctgca tcgactctcc atcaacaata aaaggagcga acaacagcca acggataaga
     4201 agaaccaaca cgacagcaat aactatggcc ttcagccact ccaacgcttc gttcttttct
     4261 ttgcttggcg gatcctccgg caacccggtc tggcccgttt ccgattgaaa ttgctgttcc
     4321 atagttcgca acctcgcttt gtcataaaat atgtaacgaa acggctatta cttaataaaa
     4381 atagtaaagg ggcttgaata aatacaagcc cccacttgat cgttaacgga ttaacgacgc
     4441 gcttctttaa ttctagctgc tttaccgcga agttcacgaa gatagtacag tttcgcacga
     4501 cgcactttac cacggcgagc cacttcgatt ttatcgagtt tcggggaatg aagtgggaaa
     4561 gttctttcca caccaacacc gttagaaatt ttacgaactg taaaagtctc actgattccg
     4621 ccgccacgac gcttaattac aacaccttca aacaattgga tacgctcacg agttccctcg
     4681 ataaccttaa cgtgcacttt caaagtgtca ccggcgcgaa agctcggaat atctttgcga
     4741 agttgttctt gcgtaatcgc ttgtacgata ttcatctatg actccctcct tccactcagg
     4801 tgttcttgcc tcttccggag aaccccttgt tctccctcat catccgcagc ggaccaccga
     4861 attcacaaca agaaaaattt tatcacattt aaccagcgtt agcaagctat aataagaacc
     4921 tctgacacct taatcactaa ggatagtttc tgcattttaa gaagcgctgt ttaaatgttt
     4981 tttatgagaa cattacaaat aattattaat agcactatta tactgaccca ataatccaat
     5041 atagaggtat gtcttgattt aagcctatta tcactccaac tacgatttca agaataccta
     5101 cccacttaat taaaacacta attgcattac gcttttccat ttacaatgcc ctccatgaac
     5161 ttaacattat ttaatgcctc tataggaatc aggagtttat tagtttattc ttttgcttat
     5221 caaattcttc tcgtgtaata aatccttctt ttaataaatt agataattta attaattcgt
     5281 ctgctgttga gtgatccggt ttattcaatt caacaactgc atcctgaaca tgctcatcct
     5341 ctgaatcatc tgaatccata attatgtagt tcaaaatatt tttccagtgc attgcatttt
     5401 tgtaattgtc ttggaataaa gggctatatt ttcgaatact ctcagggtaa tctccaaagg
     5461 taattctata gaatgatttt ttagtatcat taactacaat ttgcagttga attcctgata
     5521 cctcttcttc ggtttcgatc gtcgagcgat atattctggt ttttgaatcc tccgcaataa
     5581 ttatttgtgc ttggaagata tccttgtagt caaacacttt ttttcggaaa gaatatttac
     5641 ttagcccttt aataagtgtt ttgccagtat tatcatattc attttctaga atgcatactt
     5701 ttttcctagt ctcgtcaata gctatgcacg tttctccatc ttccgccaaa aatttttggg
     5761 aaggagtaaa atcaccatct ttttccaacg atttaagagc catttgttca acttcactct
     5821 ttaaatcttc ctcttctttt ttatccaatg atagtccttt aaaagcactg aatcctattc
     5881 ctgccaaacc aataacgaca agaaatccac tttctgttga tataccgata ataacaagag
     5941 ttgcaaaaag tagcatacct aagcagccta aacctaagaa cttcaaacta tcgcccccac
     6001 ctaatatttg ccagttaatt gtatcatttt cgacaaaata ggtctacagg actagtaagc
     6061 tggtgaaggt aaagaggaat tagttccata tatcctaagt gcttgataaa tatctatttt
     6121 accagtagcg acaaagaaaa aagttatgca agagaatgga catctctatg cataacttta
     6181 ctggatcgga gtagcgggat tcgaacccac ggcctcaccc accccaaggg tgcgcgctac
     6241 ctgactgcgc cataccccga tataattata tatgtatatg tccaaagctg ctaaaaagaa
     6301 ccctatctac gatgataacg taatagatat aatcaatccc gtcaactcgt atatgagaaa
     6361 tcgtagcata actcatacat ctatgtctag tgcttgtgcc cctaacaaga gtaaagagcg
     6421 cgcggcgatc ttcctcgctg caagcgctct tatattagct tgagtattaa ccaacgataa
     6481 tcaatcatac ggcaatactt cattcaataa ctcaaattct tcatcgatcg ggtcaattaa
     6541 gtattcactt aacatccagg taaccccctt cactgcaaaa gctttttccg gccgccggca
     6601 taaaaatcaa ggatatcatc taccgttaac atccgatcat cttctcttcg tccattatcc
     6661 tgtgactgct ttgattcgtt tttctctgtc tgttccatga agctctgcct cccaaactaa
     6721 taagcgtgat taggcgcctc tagttttatt aaccagaagc tctaatcctg aaacagcgtt
     6781 gccgcaagat cttttgtaat ccgccaaata atatacagtg acataatcat catattacgc
     6841 agggtctata agtgtgccag tctacaaaaa attgatgaac aatttacatt ttctacactt
     6901 attccgcacc tgctttcata tacaatagag ttagcaagtt aactatgaag gagagtcatt
     6961 atgagtcgct ttaagaagta tgcattaatt tcattagctt ttatgatcat tctttacgcc
     7021 gtagctgtgg caaatcccgg tacggttctc tcgcggaaag cctgcagctc ctggagtcta
     7081 gttaaggatc aggcctttct aatgactcac cccaagctag acggcagcct aaagctgcct
     7141 gccaatttca cgatccagcc cggtaccgcc gaacaggttc cagtccttat gtatcattac
     7201 ataactccta aagcctacaa cgatcaaccg gacaacaatt cgatcatgaa tctggaagac
     7261 ttcgaggccg gaattgatta cttatatgaa caaggttact atacggctac tatggaagag
     7321 ctggagcaat atgtgctcgg caaagcaact cttcctgcca agagcgtagt cattacattt
     7381 gatgacggtt accagaacaa ctatacttac gcttatccca ttttgaaaaa atacggattc
     7441 catgcggcga tttttctcat cggcagtaga gttcaaacgg agacatcagt attcgatccc
     7501 gcgaagaaaa gctttctctc gcaagaagaa atagaagctt cttccgacgt atttgaatat
     7561 cacagccata cgtatgatct tcaccacaag ggatttatga aatgtggatt gaactacgcg
     7621 tcgggctttg acacgaccag cttggagagt gatatcgcca aaatgaagga gctcggcatc
     7681 gatagtcctt atttcgcata tccctatggt gaaaaaagca cgcccatggt ctactacttg
     7741 caaaaaaaca actaccgcat ggccatgacc gtccatcaag gtttcgtcaa acctggcgat
     7801 tctcccatga gattaaagcg acttacagtt acttcagcaa caaacatggc tgatttatta
     7861 cagccttaaa ataatttgaa tcaccgtgat tattgtaaaa gcctcaccct agggtgaggc
     7921 ttttacagca acaatgatta actagtgaac taacattctt ctatatagaa ctgaataaca
     7981 gcaccgcctt ggggactgtt gcttgctctg atctcccctt taaaattcga tacgattctt
     8041 ttggcaatat atagtccaag accgaaatga tccttgtaat aatcttcctg atacatagct
     8101 tcaaataaag ctttggtatc ctgctgcttg aagcccattc ctgtatccgt gcagcaaaaa
     8161 tgaatgcgat tcttctctgg gtcatcatgc acctcaagct taatgacacc atggcttgta
     8221 aaacgaagac tattatagag aatattatcg agcactcgta ttagcattgc ttcatcaatc
     8281 caatagacta acttggttaa ttgaatctcg aatcgaatcg aaatcccctt taattgagcc
     8341 attgccgaaa attccttttt cttctccagc aaagtatcct ctaggtgaac ttgttcagga
     8401 tgcagcataa aatccacttt ttcgacttta tataatacag ccaagttgtt ggttaaatta
     8461 atcatcttgt tgcaattgct atcgatcgtc tgcttaaaag catcaaatgt aaaagcactg
     8521 ctattttgca gctgtgttat taactccaat tgacctttaa tgaccgtaat cggcgtacga
     8581 atatcatgag caatagattg aaccatcatg cttcgttcca gctccatctt ctgcaaagca
     8641 agatcagcct cttttaaaga agacaccata ccgttaaaag attgttggat tacattaaat
     8701 tccttgcctt caagctcatt gattctaaaa tcaaaatctc ccgtagaaat atgctcagcc
     8761 ccttgaagta aggaagtaat atttctggac attttctcgt acaattgctt tgtaaaaaga
     8821 actaaatata acatgaaaaa aaatatagga gacattataa gagcgatata caaaaacaca
     8881 gacaccggct ggtctttata attgtttacc acatatccga aaggcgcctt caacaaataa
     8941 acgccctgca aagcatcgtc cttcacaatg ggaatatatc tatatacata gttatttcta
     9001 acgatctctt tattcaaatt cttccacaaa tcaacactgg gatttcctat ccctaattct
     9061 ccatacaaat gatgacctga ggtatcgagc acttcacttt ttatctggtc agacatcccc
     9121 gttaaatccg gtaactctcc aagcaaaaca ccttccggat tgttctcgac cattctctca
     9181 ataatgttga aatatttcac ataataatcc gtcggctttg ccgtatcgct gaataaaaat
     9241 atgaccaaca gcaaataagc cacgatcgtg gaaacgattg taaaacttac tactttaaca
     9301 acaagtaaat aaaagtccct tttaagcgtt ttatgtctca tgctggactt cccatcgata
     9361 tccgagtcca tacaaagttt ttatgtatgc atagtccgaa tcgtgctctc taattttttt
     9421 acggatattt tttatactct cggtcaccgt gtcataatag ctctgcgact catgtcccca
     9481 aattcgctca aatatatcct ccttcgtaaa tacacgaccc ttatgtaaaa tcataaattc
     9541 aacaatctga tattcctttt tcgttaaatg aatcggcatt ccattgcagg ttaagatttt
     9601 agcgtccaaa tcaacaacaa gtcgacctga acttactttc gaagtgcctt tatcccttat
     9661 tcgctcatcg cgccgaatat gacattcgat tctagcctta agttcagcta aactaaatgg
     9721 tttttctata taatcatccc cgcctgagga aagagctttt attttatctt cttccaatgt
     9781 cttagcactc aaaaaaacaa taggacaaat gactttttcc ctaatcatct cgcataatgc
     9841 taccccgtct aaatcaggca tcatgacatc caaaataata atatcgtaat gatgatgcaa
     9901 gacagccttt aacgcttgtt ccccactgct tacagccgta actcgaaagg catacagctc
     9961 aagatactgc tgaatcatgc tgcagatgtc ctcttcatca tcaacaacga gtatgttcct
    10021 catctgacaa gcctcctagt aaaaacgcgg agtcccatgg cgttttctta tccttattca
    10081 cagctagcaa agtcaatgct actcctgtaa ctccatcaat caatccgaca taatcataca
    10141 gcttctcaat gcccgtcttt ttatcgactg tttgaaagcc aaaaggcagt tcttcattat
    10201 aatacgacat catttgctcc gttagagaag aagtgatctg taaaaactct gcatccttgg
    10261 tcacgctata aaaatgtttc gatatcattg caaggtttga taacccgtgg caaaacgttg
    10321 gacaatatat ttcctgctgc cgcacagcag cacgcttcat ggattcaaca gccggagtta
    10381 aatacttatc gtcttgtaat gctttccctg ctgcaagtaa tgaataggca acaccaggtg
    10441 tgccataaca ccacgcatct cttgtatacg tactggttac tgttaaatca ttatactctt
    10501 ctatagaaat gtgggttccc cagtaatatt ggccctcaga ttcgatccgc gactgaagca
    10561 agaaatcggc aagctttcta atggaatcta gttgtccctc ctccttaatc ccttttaaat
    10621 atgaatcaca taacgtaatc aaaagcgaag gaattccgtg tgcgagtcca atattaaaac
    10681 agccatttgg ccaacgcagc ttatccactt cggaaaactg gttagcagca gaaatatacc
    10741 accctggaac aagcttgccg ttgcattcct tgtcctgaca aacatggatg atataattca
    10801 ctattttccg atttatttct ttcatcacag gaaaattaga atcattatga aatagtaaag
    10861 tatacgctgc tactcctgta acgccagaaa tcggatcata atcctgcata tgcagatctt
    10921 gccgagactg gatctgttct aacaaaggat caatactgtt tgcaattaac tcattgatag
    10981 aggatataaa cgatgaatat cgccgcctct gcttggatat gcacaaggct gataatccaa
    11041 tgcccgcagc gccagtaaac atcgaaagag actggactcc ctcctcctct agctgctgtc
    11101 ctatacgctg catatattga tgaccaatcc gatcccagcc ttcctccgga tagtgttcgt
    11161 tcatctctcc atacaacatg caaagggagg gcaagccgtg gcttaaagac agctcctgga
    11221 aaggattgat taaacctgac tcggtctcca agtaattgct ttcctcattc gatacttgcc
    11281 gaagataatc atagtcggat aacttgcgac cgatgctctt tacaatataa tcaatctgct
    11341 catgcatcaa cgaactcctc cttcctataa ccagaaatct tggattgctc caattcatac
    11401 atttctcgat aaaggctcac gcttttcaat aattcttgat gttctccgat tccaataacc
    11461 tcacctttat gcattacgac aatacgatct gccagcatcg ccgttgacaa acgatgcgaa
    11521 ataaagattc caattttatc ctttgtcatt tgcaggaaca tatcgataat ttgcttttcg
    11581 gccataggat ccagtgcaga actaggttca tccaagatat acaacgaggc atcccggaaa
    11641 aatgatctag ctatggccac cttctgccac tgtccgccgg ataattgctt cccttcatca
    11701 aaccaaagtc ccaattgagt gtccagatcg ttctcaaaat ctacctttcc cttgaacaga
    11761 gcttcactaa tggcttcttc ttcatgcatt ctatcaatct gcccaaagcc cacattttcc
    11821 ctcaaggtca gttcgtattt cacgaaatct tgaaacagta ctgtaataca gctttgcagt
    11881 tgttcggttc tgtaactgtt aatcgactta ttgttgaact gaatcatgtc atcatcaatt
    11941 tgatacattt taattaataa ttttacaagt gtgcttttac cagatccgtt cgtgcccaca
    12001 atcgctattc gttcaccacg ccgaaactcc aaattaatat tgttcagaac cggatgagca
    12061 aaggatgggt acgcaaacgt taaatcgcta atttttatag tttcgattcg tgagatagta
    12121 ttatctgcag cggcaggtgt ttctaaagta tctaccgatt ctccagcttc ctccaatgcc
    12181 aaaaaatcaa atagctgact catatagaga ttactctgat acagtgtata tatcgtatta
    12241 attattaact tcgaattgct ttgaattaaa ctcagcgcct tgataaaacc aacaacatta
    12301 cctatcaata tctcaccaag atatgccgaa taaataatga taaataacac aacattagta
    12361 catatttgct cgatgaaatc aaatagaact gtaaacactg tccttctttt gaacagagct
    12421 atatcctgct taataaattt cttgttaata ttctcaaatt tgcttaatac gtaccgacta
    12481 attccatata atttaacttc tttaaatgta acatccttcg tcagtaaata agtcaaatac
    12541 caactcttcc ttcgttctga cgttctgttc cattcgacat tgtactctct ttgcccgatt
    12601 cgaaaaaaat aagtagataa tagcactgga ataacgatca gaattaatag tacccaaggt
    12661 ttccaattta gcagaataat aatcgaggaa atcagtgtaa tgaaagctgt tatcatcgat
    12721 ataattgctt gaaaaatttg aaagggtcta tacgctacct cgctttgcac ccgctgtagc
    12781 ttgtcataca cagcagcatc ctctaaatgt gcaagggtta atttgctgca cttttccata
    12841 acactataat taattttaaa acgaaggatc gtttcgaact tttgttcata gaaactcttt
    12901 atactattga ttacgtcgct atataaatgt aaaacaatat atatcccaaa agcccagacc
    12961 accgcctgaa acgtccccgt tacaagcata ttcagcaaat gttgtgaccc aaaaagcgtt
    13021 aaaatcgggg agaatcccac cagcaaactt aataatgaaa tcataaagaa atttcgctta
    13081 tcggaagctg caactagcct tagcgttttt ggcagcagct tcatcgtctc tcgaatatct
    13141 ctaaagctta cacgatcatc aaccgtatct gtgtcattca gcgttttctt gttcatcagc
    13201 aatttcctgc tttctttaca agttatttgt agacctgtgc attctgctgc actttagtca
    13261 gatgtatctg ctgatgctta agcacatata aagtgtgaca ggtaagagct ctgagtttct
    13321 tctcaagttc tcggtctatc ccaaataaac ggttgcaatg catatgaatt aagctatcta
    13381 caatagccca agggtgggtt gataatcgag aaagattact gttgatttgg gcactgtatg
    13441 atcgtacagc actgaatctt tcatttaaaa gattgaatag actagcctct tgagaatcgg
    13501 tttgtaacgc ctccatctga ttcatggaat gacaaacatt tatcaactgt gatcgcactc
    13561 gcttgaaatc atcccggtag tcgcttggct tgacttgaga agacagaaat tctaattgca
    13621 tactgtaatc ccatccccat tgctccatat aacatatcgt tgctgcaact ccgactattt
    13681 catctgacca atcgataagt ttgtcttttc tcgctttaat caacttttca acagtaacgc
    13741 tatcctggca aaacacttgc tcggcagctt ccataaagaa taaaccgccg tatctctcaa
    13801 tttcccgatc ataacaatcc agcacaaaat ggcttataag gcctttctct attaaggatc
    13861 ttagccacaa ctgaatatcg ggataagcct ctagcaactg ttgctgatct ccacgaatcc
    13921 ttaagcggac atgcggattt gggtcagcat aacgcaaata gaaatggcct ttaacccgct
    13981 cttgatttat aagctcggcg caataatcag caatctctac gctaataagc tcttcctccc
    14041 tagattgagt cccgtatagc tttaaataaa tccattcctc aaagggcagc ttcaaccgat
    14101 caggcgaagt gctggaaatc ccgttaaacc tttcctccgg ataagcagcc ttaggatttt
    14161 ctaccgcttc ttgagccatt tttatcatcg gtattacgat ttcttgagca tgtccatcca
    14221 tatccccgcc ccaggccttt tcaaggaaat cctcaacagc ggttaacatc acattattgc
    14281 cattgttcac gaactcgtgg taaagaattt tcaaacattt ttgatcatct aaattcataa
    14341 taattctgtt atcgcctgaa gcaatatatg catatttcgg tatatttcta gaatggcgat
    14401 aacccgtaaa caactccata aatctcttaa acccttgacg cttatccaac tttattgttg
    14461 aagaattcag aacccacttc tccggggcca gcacaaagtt ccgatattta atcatgggag
    14521 tgtagggtaa atccctaaag ataacctccc aagggaaatt ataccacttt ctctcgtctt
    14581 ctaggctaat atcgtataaa aatcgtacag catttggaga aatctgtgga ttcaacatat
    14641 tattaaaatg aaagattatt tttttattga gacgcttgct cttcgcataa aatgaagtcc
    14701 cttctacacc aatcaaaata tcattcaagg ttaaagaata aaatggttct ctagagctgt
    14761 ttgtaaaaag ggccagctcg tatttattcc catgaatatt ccttgtaaca ttggcgtttc
    14821 gcagctcatt aggcaaataa gaaacctcgc agccgatata ctcttcacga tcaattaaac
    14881 cctgatttaa ttcgtgcagc ctatcgaaaa atttctcggg agaatccatc acatgggcaa
    14941 agcgtccaaa actttttcct gctttcgtag atccaacatt tggaccgaca taatatagtg
    15001 gctcatccaa attattttta tcagcaaaga ttaaattaat ttcaaaggaa tctggaagtt
    15061 cctcatacgg acaactcggc aatgagaggg ccagaatatc ttcctcttgt atttctatac
    15121 aggaacttcc atgggtcagc gcttccaaat atttattcca aaaatatgcc tgtactttct
    15181 catgaaaata cggggtaact gagctgcttt gctccacccg catactgggc gggtttgtat
    15241 agccggaagg cgccccgatt ccacgatctc catctatcat ttcaagtaaa ggaacttccc
    15301 tattttggcc gtatttctca ataaaatctt gacgatactt atttagtgac aaccctgttt
    15361 catcaggagg ccttaggaag cccaataatt tgttgattaa gtgatttact tcctgaagaa
    15421 tatatccgtt taatcgaata ggctcatcac cttgtaagga taaatctacc tgtaatggag
    15481 atttagattc cataacctca gtcataagcc gatgaagctc cagataattt tcttctccag
    15541 cccctagtgc agtacagtta taggcatcta ttttagattg gatttcttta agcttgatga
    15601 gaagctctgc atcacccaat ctctccgtta gttgcttaat tacataatcc agctgatcaa
    15661 ttacagttag tggcggccta atattagata tcaaatactc cttctcaatc aattcctgca
    15721 aaaaatgctg aaaaacatgt tgctcaattt ccggatagtg ttgttcaaga gcctttacaa
    15781 gctgggagaa cgaggctgat tcagccgcag cttcataaac aatatgatag gccttcgttg
    15841 ctctgatatt cacttcctgg atacttcgcg tatccgtttc ttttaaggtt gaatgtggca
    15901 atacaactct atttcctttt acaaaagagc atttattatt gctgtaacac aacgcttctg
    15961 tgtaatccgt ctcgatcttt ctaaccaatt tcattagcca ttccaaatcg ggtctcgcct
    16021 tctttgtata tttacgggaa cccaaaagag ccgtgctttc tttcgtaaac tcaccaaatc
    16081 cgacacctgc gaataatcca aacggagttg gtcgagtgct catcctaatc aaatatttat
    16141 aaagtgaatt catgaaatgt tctttcttct taagaatctc ccctttcgaa aataaatcca
    16201 tagtttcgta caaattttta ctggctacta atatgctttc tctgaataca ctgttttcag
    16261 accatttttt aatatattcc tccgcctcat cctcgctgat tccctcatta aaaaagtgat
    16321 aatatctcga caatggcaaa atagccgaac gaatcataaa agttcctgta tcttgaaacc
    16381 actgttgaac cacctttttg acctcctaat aaaaaatagt tcttatattt ttaaaaggta
    16441 caaaggagtc gaaatcaact tcgcctttgt accttttaat gtggttagac aaaatttata
    16501 actagcattt tacgcatgag tgtgagattt cgcagccttt tgtaaaacac atcagaacac
    16561 ctgtgatgca tcctggagtg caaagacttt tacttgtaat ttgtggctcg actttactaa
    16621 ctgatgtttt aatttgaaca tccaattcaa aatcatccag tttggccatt taacttcctc
    16681 ctttctattt tttatatatt tgcattgtac aatccaggat tctaatcctt agatcttcca
    16741 atgaaatatc aaactaataa aaggattctg ttaatcttct aactaactaa ataatagaat
    16801 acaattctaa ggattttata atttttctac aaaaatcatt taaaggaatt attttataat
    16861 taatcctggt aattcatttt actccaacga attgacaaag ttaagataag cgctactgat
    16921 agcaggagaa tatagaagag actcagtaat ggctcatgtc cagtaatgat gtcataaata
    16981 aaggtaaggg cactaaacag aaaatcaagc aggaaagcag acagatacat cccagctatg
    17041 agtacagcaa tatccgccac tacagctact gcggtgtttt ttatacaggt tgaaataaga
    17101 ctaaaaataa aggaaatcaa taaaatctta gcgaaataga taagataata aagcagatta
    17161 aatcttaagc tttgcatggc cgtcaaggtg gattggttgg aaactaaagt agtcgaatcc
    17221 acactaggca taaagataaa agccgaaacc tggctaacaa taaaaataac gaaaataaaa
    17281 aataaattac ataaaacaag taccgctaac ttgccgagca gtaatcttcc cccgctaata
    17341 ggccgggtaa gcaccatcct gagactgcct gaagcccgat catctccgat taaaagtgat
    17401 gaaataaccg gcagaacaat gaatacaagg aaaatatcca aattgctcaa tacagcatgg
    17461 ggtaacgtca gcctatctgc attttgcaat attggccctt catttgattg ataatttatc
    17521 gctgccagca tagatttagc caacatagag tcgccttctt gatttactgc tgagaacccc
    17581 agcgatagaa gcagtgttga tatcacaatg agtatcgtga atatataaaa ggtttttcga
    17641 tgaagaaatc ggtataattc actttggaat atcccgctca taggtttccc cccactttct
    17701 agtccttaat ctgtataatc gctaactcgt tcatgccaaa atgcaagaac gttaaatact
    17761 atcaaataga tcgcgaaaac aatcgcaatg tctttcgtca gcccttggat tccacccaaa
    17821 accgaggcaa tgcctgtaaa ttgaatttga acaatcgaag catataaaag cacatcaatt
    17881 cgcagaatgc cgagctcgta gagaatacta atcacttgcg tgtaaatcat actaataatc
    17941 aaaattccaa ttccgatccc tgcagtgatt attttattct tggctaagat gctaacccag
    18001 gtcatcaggg acaacatgcc gagaacagat agaaaagcca agccataata ttttatggta
    18061 taactaagtg cagacaagcc ccgaatagga acataactga aaaaggtata cgcgtaatca
    18121 acctttggca tcaataaata gcctgcaatc caggacaatc ccaagcattc cacgaacaat
    18181 ataaaaaata cgatggctag cagcagcatt ttgctggcta ataccttcca catggtgtag
    18241 cccctagcga tcacttgcct taactcgccc gatcttcgct cctctgtaat tacaatggct
    18301 gtataaaaaa ttaccagtcc attaaaaacc agcattaact gctcttgaat aaccaggtaa
    18361 ggaaaactta tttgcgaagc aaagctggga tcctcaggcg ctattgctga aagtgtaata
    18421 ttgtttttcg ataggtataa ataagataga gctataagaa atggaacagc caggaaggac
    18481 agccacatga ccttcctgcg aaaaaattta tacccttcat actttaataa ggccaacaat
    18541 ttattgtcct ccgaacatca attgaagaaa agcatcctct aagtgctcgg tgcctccttc
    18601 gatcagaata ctctccttgc tgccttgctt cacgattttg ccctcttgga ttacgatgaa
    18661 gtgatcacat attttctcca attctccaag aaggtggctt gacacaaata tcgttactcc
    18721 ccgttcgcga tttaatttta aaatgatgtc tctaatctct ttgattccca tcgggtcaag
    18781 tccattggtc ggttcatcta agatcaacaa atcgggatga ttgagcaggg cctgcgcaat
    18841 gcctaatcgc tgcttcatcc ctagggaata gccttttact ttatgatgct cccggccagt
    18901 caaaccaacc agttcaagca cctctgcaat tctctttttt ctctcctgtt tactcatgga
    18961 gctgtccagc atggcaagtg catataagtt ttggtatcca gtcatgtata gcgagaacac
    19021 cggggtttct accatcgcgc caacctctct taacgcttcc gtcttattcg atattgggac
    19081 tctattcagc ttaacgtcac cctgaaacga tatcagacct gtcaaaatac gaattaaagt
    19141 tgttttcccc gctccgttcg ggccaataaa tccggtaata ctaaattttg gcacattgaa
    19201 gctgaccgca tccagcaccc gccttcttga tagaacctta ctaacattgt taacttcaat
    19261 taaatgagtc atccacatcg cttcctttct ttaaaacata ataaacagca aatatcatgt
    19321 tttaataaaa aaaacgccat ttaggcgttt ttttaatcaa gactttgact cacttcaata
    19381 ttcagcttgt aattaaaaat tcttcgttta aatcatctta ctctccttgc tctgcctgaa
    19441 tctcctgcag ccatttgcga tccttcggag tgagctcgat atgctccagc aaatcaggac
    19501 ggcgcagcca cgttctgcgc agcgcctcct tgcgccgcca gtccgctaca ttcgcatgat
    19561 gcccactgag caggatatcc ggcaccttcc aacccctaaa ctccactggg cgggtgtaat
    19621 gcgggtactc cagcaatccc gtactgaagg agtcgctaat ggcactggtc tcattcccaa
    19681 gcacgccagg cagcaaacga acgacactat cgatcacgac catcgccgga agctccccgc
    19741 ccgtcagcac gtaatcgccg atcgacagct catccgtgac aagatgttcc ctgattcgct
    19801 cgtcataccc ctcataatgg ccgcatatga agatcagatg ctcctccttg gccagttcct
    19861 ccgctttgcg ctgcgagaag ctttcgcctt gcggacacat caggataata cgcggggctg
    19921 gcgcattggc aggctggaca gataacagat cctcgaccgc tcgaaagatc gggtcaggct
    19981 tgagcaccat ccccccacca ccgccgtacg gcgtatcgtc tactgtaccg tgtttgtttc
    20041 cggcatagtc ccgaaaatta accggcttta gcgatacgat ccccttatct tgagccttgc
    20101 caagaatact cgttccaaac acgcctgaga acatctccgg aaatagagtt aatacatcta
    20161 ctttcatcct tatagcagcc cttccatcaa atgaactttg acgatcttgg cctccacgtc
    20221 gacatcaagg acaacttcgt caataacagg gagcaaaagc tgcttgcggc taggcatttt
    20281 aaccacccaa acatcgttgg cgccagggcg aagtatttcc tcgatcacac caagctcttt
    20341 tccttcttca tcgatgacgc ggcagccgat aatttcatag aagtaatatt cattatccgg
    20401 cagcccgacg gatgcacctt tgctgacttt gatatcgaag cccttgtact tctcgacctc
    20461 attaatattg tcatagcctg cgaatcgtac aatgaacatc cctttgttcg ggcgcgcaga
    20521 agctacagtc acttcaagtt gctcgccggt ttcagggtga acgataatca gcttgctctt
    20581 cggagcgaag cgcacctccg ggaaatccgt actcgataac acctttaatt ctccacgtat
    20641 gccgtgcgta tttacaattt tgccaacaga cagcaatgaa tccgacataa cttcctcctt
    20701 gaaaaaaatc atcactcgca gaactgtgtt ccatctcccg cttcagcttc agcatgtacg
    20761 aaaaagggct aggacagtca tcctaaccct ctttcgtata tttttaagat atgatatcaa
    20821 cggtgacccg cttatccatc ttaacggctg ccgatgctac aaccgtgcgg agcgccttag
    20881 cgattcttcc ctgcttgcca atcactttcc ccacatcatc aggatgcacg gacagctcat
    20941 acacaatcag gtgttctttc tccacgacct ccacacgaac atcgtccgga tgatcaacaa
    21001 gagccttcgc aataacgccg actaattgtt ccataaaggg accctccgaa tcagcaatta
    21061 tttttgctgc ttaagctcat gaaatttctt cattacgcct gctttgctaa gcaagttgcg
    21121 aacagtatca gatgcttgcg caccgttctg aagccagttc aacgctttct cttcgtcaat
    21181 gtttactact gccggctcag cgaccgggtt gtagtaacca atttcctcga taaaacggcc
    21241 gtcacgcggg gaacgggaat ccgaaaccac gatacggtaa aaaggagctt tatgagcacc
    21301 catgcgtttc aaacgaatac gagctgccac gaaattcacc tccttcaaag aatgaacgat
    21361 taaatatcat actggcttat cggaaaggaa atctcatccc tttgcctgct ttgccctgca
    21421 tttgcttcat caacttggag cccttgccct tcggccccat catatcggag aattgcttca
    21481 tcatccggcg catttcatca aactgcttaa tcagccggtt cacatcggca agcgtcgtac
    21541 cgcttcctgc ggcgatccgt ttgcgtctgc tgtggttgat catatccgga ttctgcttct
    21601 cttctttggt catagagtgg acgattgcct caacgcggcc catctgcttc tcatcgacct
    21661 tgatatcctt catctgcttc atcttgccca tgcctgggat catatccatg atctgatcaa
    21721 ttgggcctag cttcttcact tgatccattt gctccaggaa atcatcaaac gtaaattccg
    21781 cattgcgcat tttgcgttcc atttccttcg ctttgtcggc atcgatattc gattgcgcct
    21841 tctcaatgag agacagcata tcgcccatgc ctagaattcg cgaagccatc cgctctggat
    21901 ggaacggctc aagcgcgtcg atcttctccc cgagcgctgc gaatttgatc gggcagccgg
    21961 taaccgcctt gacggacaac gccgcaccgc cgcgagtatc gccgtccagc ttggtcagca
    22021 cgacccccgt caactggagc tgctgattga agctctcagc cacgttgacg gcatcttgcc
    22081 ccgtcatcgc atcgacgaca agcagcactt catccggctg cgttatttca tgaatctgac
    22141 gaagctcctc catcagttct tcgtcaacat gcagccgtcc cgcggtgtca atcagcaagt
    22201 aatcgttgcc gttatccttc gcatgctgca aggcctgtct ggcaatctcc acggggctgt
    22261 ttccctcggg aagcgagaat acgggaacct tgatctgctc gccaagcacc tgaagctgct
    22321 taatagccgc tggacgataa atatctcccg ccacaagcaa aggacggtga ttccccttca
    22381 ataacagctt ggccagcttc gcagaagtcg ttgtcttacc cgcaccttgc agacccgcca
    22441 tcatgacgac ggtcggcggt cgattgctct tcgccagctt ggcttggctg ccgcccatca
    22501 gatctgtcaa ctctttgtta acaatatcta taatgaccat gcccggcgtg aagctgtcca
    22561 tcacttcctt gccgacggcc ttctccttta ccttggagat aaattccttg accactttga
    22621 agttgacgtc cgcttcgagc aatgcgagcc gcacttctct catagcttcg tttacatcgt
    22681 cctccgacac cttgcctttg ccgcgcaact tactgaatac gccctgcaat cggctcgtta
    22741 aaccttcaaa agccatcttc ggtcacctcc gcttcaaggg ttatatacta tgaatccctc
    22801 ataaatcatt cttcctattt ataattgctc agcttggtcg agcaggctcc ttgctctctc
    22861 cttatgtacg gcggacaact cactatctgc aatcagttcc ccaagccgaa caagcaccgt
    22921 actgagctct tcatgcttat gaagcagccc cagcttctcc tcgtatacct caagcattcc
    22981 ttctgcccgt ttgatatgct cataaacggc ctgtctgctg attccaaact cggctgcaat
    23041 ttcgccaagc gagaaatcat catggaaata atatttaagg aacgtctgct gcttctctgt
    23101 aagcagcgtc tcatagaaat caaacaaaag gttgatccga ttcgtcttct caagcctatt
    23161 ctcctgactc atatgggcac tccctccgtc aaggaaaaac actttacagc gcgcatcaac
    23221 gttctttatc atacctaatg gaaagtagga tgtcaagtag tttcccttaa catatcatcg
    23281 acagcttttc ttcaaaaatt tctgcctgca aatgaacaag ggccgcatgt cattcaaacg
    23341 gacagcggcc ttgtcatatt caaattacag gcaatattta gaccttacca cttaggcagc
    23401 agatacaaca aaatggcgaa gaaatgcgtg acactgcctg cgagtacgaa caaatgccaa
    23461 atcgcatgat ggtaaggaaa agcccgccat acataaaaca ctgtgcctag cgaataaaga
    23521 ataccgccag ctacgagcaa tgctatgccc tggaaaggaa ccgcagccgt cagcggcccc
    23581 cacgcaataa caatcagcca gcccatgatc aaatagaaga acgtggacat gaacaagaat
    23641 cgtttgacaa agaatgcttt gaacagtaca ccgagcaagg cgattcccca aatgaccccg
    23701 aataggctcc agccaagcgg gccgcggatc gcgacaagta ggaatggagt atacgtgccg
    23761 gcgatataaa ggtaaatgga ggagtgatcg aaaatttcga acaaatcctt cactttgcct
    23821 tctttaaaac tgtgaacgag agtggagcaa acatacaaca gaagcatgct gaccccataa
    23881 attgtaaagc tgactacgtg ccaggccgtc cccttcaagc tggaaaaaac aatgagcaga
    23941 acaagcgccg ctacacttag tacagttcca atcccatggg taatggcatt ggcgatttct
    24001 tccctgcgcg gataagtatg cgtatttgcc atactgtatc gcctcctaga tttttggtat
    24061 gcttctctct aaattaatct tggcttgccg tataatcttc ctctgccgct tcttcttcct
    24121 gaatcagtcc agcgaacaat ccgtgaacaa actgctcgga atcaaatctt tgcaaatcat
    24181 cgattttctc tccaaggcct acgaacttca ctggaaggct cagctcttga cgaatcgcga
    24241 tgacgatgcc gcccttggct gttccatcaa gcttcgtcag tacgagtccg gttaccccgc
    24301 tcttctcacc aaacaacttc gcctggctca gtgcattctg acccgttgtg gcgtcaagca
    24361 ccatcaacac ttcatgcggt gcatctggaa tctcccgttg aatcactcgg taaatcttat
    24421 tcagttcctc catcaaattc gacttgttct gcaaacggcc tgccgtatcg cagagcagaa
    24481 tgtcaacgcc gcgctgctta gcggcctgga cagcgtcaaa cataacggcg gccggatcgg
    24541 aacccggctg ctgcttgacg acgtctacgc caacgcgctc accccacacc tcaagctgct
    24601 caatggcccc ggcacggaac gtatctccgg cagccaaaag cactttcttg ccctgctgct
    24661 tataatggtg agccagcttg ccgatcgtag tcgtcttgcc tactccatta acgccaacaa
    24721 atagaataac actgatgcca tggggattca gcttcattgc gttatcctca tcgccgcgaa
    24781 gcagctctgt aagcttctcc gataggatcg gctgcagttc agccgcgtcc tcgatccgcc
    24841 gtttcttcac ttcactgcgc aaatcgtcaa ttaatgtaat tacggtattc acgccgacgt
    24901 cggccccgat taatatttct tccaattcct cgaaaaattc ctcatcgatt tttttgcggc
    24961 gaatgacgag atcagtcact ttctccacaa agcctttacg gcttttttcg aggccgtcct
    25021 taaattgctt cgtcaccgtc tccgttttag atgcgatgct gtccttcaat tttttaaaga
    25081 aactcatgag gttcctccct taagtaatct tcctggatcc aattccggaa ctatctgtga
    25141 tgttctaatt atgccatggc ttagcggctc aagcaatttc tacggtctct tcatcctcca
    25201 gctttacaga gacaagcttg gataccccgc cttcctccat cgttacccca tagagaacat
    25261 ccgcttcttc catcgtccct ttgcggtgag taacgacgat aaactgggtc tgttcagaga
    25321 attcacgcaa atattgagcg aagcgcgcca cattcgcttc atccagtgca gcttcaacct
    25381 catcgagcac gcagaacggc acaggcttca cgtgcagaat tgcaaagagc agcgccattg
    25441 ccgtcaatgc tcgctctccc cccgaaagca gctgcaggtt ctgcaacttc ttgcccggag
    25501 gctgggccac gacatcgatt cccgtctcca gcagattctc tggatcaatg agcacgagat
    25561 ccgcccgtcc gcccccaaag agcttggtga acacggtacc gaattcccgt cttatggcgt
    25621 cgaaggttat tttaaaacgc ttggacattt cgtcatccat ttccttaatg acctgataaa
    25681 gcgtcgtctt ggcctcgacg agatcatcct tctgctcgct taggaattga tagcgctcgg
    25741 acacccgctc gtattcgtca atcgctccca gattcacttc acccagcatc gtgatctgcc
    25801 gtttgagctc tttaacttct ccttgtgtct ggggcacgtc ctccggtaca gcgtagcgct
    25861 gttttgccag ctcaaagcta agctcatact cgtcgctcag cttatgcaga atattgtcaa
    25921 gctccacatc aagcctgttc gcttgaattt ctgtttgacg aagctgctcc tcaacggcct
    25981 taaggccaat cctttgctcc ttcgtctcac tttcgccgtc ctcgagcttc ttaaccaata
    26041 cggttcgcga agcgcgctcc atctcaagct gctcgctcgt acgctctttc tttaacttga
    26101 aatcgttcag ctcttcgcgc tgattgacgc tttgcaattc attctgcttc aaatccgcct
    26161 caatcgattg tagaatgctg cgattctgct ctaattcttt cctctgtatt tcgaattctt
    26221 cctgcgagcg ttgcagttgc tcacgaagcg agtggcactc ctgatccagc ttgccttctc
    26281 gtactttaag tccggtcaat tgatgctgca attcttcctt cacggactcg ttcgccttac
    26341 gggcaaattc cgccgcctga atcgactggc gaatcgtttg ctcctctttc tcc
//
