LOCUS       NZ_LT732548            22456 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Paenibacillus bouchesdurhonensis strain Marseille-P3071T, whole
            genome shotgun sequence.
ACCESSION   NZ_LT732548
VERSION     NZ_LT732548.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus bouchesdurhonensis
  ORGANISM  Paenibacillus bouchesdurhonensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1
  CONSRTM   Urmite Genomes
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2017) URMITE, 27 Bd J Moulin, 13385 Marseille
            Cedex 05, France, 13385, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900155685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:11:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,206
            CDSs (total)                      :: 5,108
            Genes (coding)                    :: 5,019
            CDSs (with protein)               :: 5,019
            Genes (RNA)                       :: 98
            rRNAs                             :: 8, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 3, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 31 of 89
            Pseudo Genes (incomplete)         :: 75 of 89
            Pseudo Genes (internal stop)      :: 9 of 89
            Pseudo Genes (multiple problems)  :: 21 of 89
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:18:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2772085
            Orig. end                         :: 2794541
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT732548.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22456
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="8"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22456
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22456
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12456](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12456
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(696..707)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            937..1821
                     /locus_tag="CZ379_RS16790"
     CDS             937..1821
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS16790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_110932673.1"
                     /transl_table=11
                     /translation="MKKTKINRKWLVLPLCAGLVASLITPGSIGFAEEFVGKMNEVMFG
                     LPSRDHMIQVPDQEPHLQFELNHDLEPFTGFHTEEQVVFENEEIQPEVNPAVARTLTVD
                     VEKKDLFQLTEEQMEELVTGGYSIEDVYQLDHLANKLIIEPMELAERRDASGLDWNELE
                     VQVTRENQLKQLSQLSEEHPQAYAQLSRETLEDEEQLIILIAFDMGKGTIAELIKAYQT
                     GGEQAVANYQPQPNAKMQTQSVKSNNSNSSVDADVLKSIRSIAEETGISESELIQQYHA
                     AKEASKHALAEKE"
     gene            1826..6955
                     /locus_tag="CZ379_RS16795"
     CDS             1826..6955
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /locus_tag="CZ379_RS16795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="WP_199925647.1"
                     /transl_table=11
                     /translation="MRKVAAFIRNCIVAVLVFVIASQSGVSSVHAQIDSQQLERVLNGL
                     VTPKLVNESNKPNLSDRSMVSETVDPASGTLALYETDVSLPGKDGLDLTLGRIYNSNQA
                     EVGTKRVSVTSSTSQRAGWGSGYYVTILYWDKNTNKYGTHFPGYYSTTTAAHNIANHYI
                     KNQPDSSRVYLDYDMEYKDVLYIQVTYTTTTKIYPDENSYSRLRYDLGGGWSLAFPSLQ
                     IEGTYLHYHDGAGAAYTVKFDANNRGKLEDYSRNDVELLRDTGYSNGQMTSTYVLVDQN
                     KKKTYFGSDGRLLGIKDRFNNEIKFTHINRTLNGRSYPVISKIVDSIGRNVDFAYQSNL
                     TDPNFDNQNMTENITITISHPSTSERRSIVYAKKREEVSIFENGSLIGRRYEPYLYRVT
                     DMKGYSTYYEYYLASEKFNATSKSLNNSAGTAVYLLQYAMYPHSSSFYEYTVVPRNWGG
                     QGAYQAFQVTKRWDGLNRYNYDAANPSMYAEGPYNQRDYTYFGDVTGYPTYYAEESIPE
                     SYRFGSEYVNQDGIRTKYTFNGKKQLLMTEQTAANGEKITETVQAFHTAYKYKPTKIET
                     KTTSGTRENKLYQTYDYYDWGDLKSTTRPLTAAQLNDTTQVQQHTTTYDYDTNYRLPIK
                     IEYYQSADNLLTEQFTYDAQGRLKTAQNANGEMTTYHFTQASDGRTEEVIMPLENGKTA
                     KTVSHYSQSGSYQLFPTTIKSYYTNESGQQVEVSVQRTYNVLLGLMTSETNADNKTTQY
                     QYDVYGRLTKTLYPATNNQSGERYQTEEVFVYNDQTVDNTPNYFDSENKYLITTRVDSH
                     TMTTRLSDSAVNYDNITHEFYDGFGNAVLIGQLDNTTNRHLIVAQYHYDVMTRPNYVID
                     TSHNVSTAKYDAWGRAFESTDPFGNLYRTDYDIIDRKSTSYMVAASDIASFRNSPQDGL
                     KRNVLETTSDQWGRGISSKAFSNWPNRTAGVVQEDVAYDHLGNVISYTNPNRNTTSYRY
                     DKHNRLISVVDALNQTTSYSYNKLGQLQSISQSEGSKTWATTKSHDETGFLRTSTDPAA
                     NQDVFTRNKLGQIASRKDPNNTLISYAYDETGRNIIKVAGSTTLKNVYQYRIFGPLRQE
                     EIRNGSNYMTVYNDYNIFGSLKYKATVYDGVATVVRHEYDDQNRLKNVADAFDYFTHYS
                     YDKTRISRVQTNGTYSLTTAENANAQYIYEPDGKLKRVTYPKLTDGSFLTSDYAYDGIG
                     RLLKVTNKKGTTILSEYQYQYDANGNITAVTDGAGTTSYQYDKLDRLIQVKRPSGQTIV
                     YTYDARGNRKTLKGDSLIEDSNEQTYTFNIWDQLKSVAKENVTTEFEYEMQGLRLSKTT
                     TTTPAHESGTATPPTPVTEKVRYAYNNSGQVISESDASNRAIANYVWGPDRMLAKRDVA
                     TNKKYYYLYNGHGDVVQIVDENGTKVNSYQYDEWGNILAQEEGIRNSFKYAGEILDQET
                     GLYYLRARYYNPEIGRFVSKDTYEGNVTNPLSQNLYTYVHNNPLIYTDPSGHKVWLIHG
                     TNLKKRKNPEATWTPEFIDYIGNLYNEDVATPRWSGGKTGNNKAAREKAAEAIAEDILK
                     WQEKNPDDPIRLVGHSHGGNVAILVANILGEKKIKVDTVVTVATPVRGYQLKQEVGQHL
                     HVYSDRDSIQVNGGTPWLLLKAGRTFSAAANVKIDVDKKYNNIEAHSAMHSNVDVWKQY
                     IQSLLADFYVKP"
     gene            7031..7657
                     /locus_tag="CZ379_RS16800"
     CDS             7031..7657
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012685494.1"
                     /locus_tag="CZ379_RS16800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_110932675.1"
                     /transl_table=11
                     /translation="MLLLIRGVWILALLINLSAVMWFIFGTTANFQRGMDLVSTVIFVY
                     FGIPSILLIVLSIFLIIKGWIPSSPWRIVAVSILILGLLSLSPTLFKYVDTSGWLEENV
                     TTDTLQITSDNAYEYNLEIINLFQRNSYARLHLKSTSTDEEIRIPLDIPVKEIVVLFEE
                     KNYHLIFLKATSEADVYILHPTSKLPFPNEKYKIDVKKKEAVKIP"
     gene            complement(7774..7938)
                     /locus_tag="CZ379_RS27075"
     CDS             complement(7774..7938)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024729.5"
                     /locus_tag="CZ379_RS27075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_324616461.1"
                     /transl_table=11
                     /translation="MLFFKSFSHLKTEELYPYHIRNLEEIHIRFYNQQRPQWKLNKLTP
                     ILYRRQLAS"
     gene            8699..9355
                     /locus_tag="CZ379_RS16810"
     CDS             8699..9355
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS16810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_110932676.1"
                     /transl_table=11
                     /translation="MQTEISNKFPKKHYNIFGSLDAFDYFTHYTYDKKRISQVQINGTY
                     SLTTAENADAQYSYEPDGKLKRITYPKLTDGSFLTGDYAYDGKGRILKVTNKKGMILSE
                     YQYQHDANGNISADVPDENATNFGRTIFDAGVGKWYPESSFHINWDRTVISDAYIGCAY
                     DSQCGGFVGAAIVEIPAAYNIAKSGGSKSTGFVKGLINKKITANTKSYKDIQRKH"
     misc_feature    complement(9507..9521)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.3"
                     /tool="antismash"
     gene            10001..10255
                     /locus_tag="CZ379_RS16820"
     CDS             10001..10255
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="CZ379_RS16820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_110932678.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.6e-16,
                     bitscore: 58.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-12, bitscore: 45.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRKDDQIYEAQENGEFVLLNLRTGQFYGLNHIGSEFWKLLFTTE
                     MSEIHQYFEKAYKADPVIVRRDLEALLSDLIRNGLVHRS"
     aSDomain        10007..10249
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CZ379_RS16820_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.00E-18"
                     /identifier="RREFam002.1"
                     /label="CZ379_RS16820"
                     /locus_tag="CZ379_RS16820"
                     /protein_end="83"
                     /protein_start="2"
                     /score="58.1"
                     /tool="antismash"
                     /translation="RKDDQIYEAQENGEFVLLNLRTGQFYGLNHIGSEFWKLLFTTEMS
                     EIHQYFEKAYKADPVIVRRDLEALLSDLIRNGLVHR"
     gene            10252..10662
                     /locus_tag="CZ379_RS27185"
     CDS             10252..10662
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="CZ379_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_110932679.1"
                     /sec_met_domain="PF13471 (E-value: 2.5e-18, bitscore: 64.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRYFQFIQVAFALIRFQIELRIYGFQKIFPKYVERYPIPKHSEN
                     ERNHIGQMNHLLRTIDMACALAPFKAECLHRSFLGFRFVRTKCSIPVDLVIGVKKFPFT
                     SHAWLVLNDKNINEAEGYTKQFIIILSSKGLK"
     gene            10669..12456
                     /locus_tag="CZ379_RS16830"
     CDS             10669..12456
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="CZ379_RS16830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthetase B"
                     /protein_id="WP_110932680.1"
                     /sec_met_domain="GATase_7 (E-value: 5.9e-16, bitscore:
                     56.5, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.3e-36, bitscore:
                     125.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWFSGVIKLDHSELSFEEIGRINRNTSFNYNVYKHQIIQKSLAL
                     FSIDSSYEHNPITHKDNCYFVGDVRLDNRKELLTLLPFLGADISDEQLILHLFQEKGPD
                     VFSILLGEFSFLIWDTSRYQAIFVRDQLGIKTLFWSLQETTLYFASDIFLMESCIRLQR
                     INDEYFFDFYKSNASADNDITPFKDLFRIRSGTRVLVDTRGANSQRYWSIANVNQSINY
                     RDLSEYIEHLFHLLAESVQYRLNSTHPNAVLMSGGLDSTSVFAIAQHLSKFNSGYKTFA
                     VSGVFNLHKSSDEREYIHPVLQQYEVEPRFEVCDDYGVFYNFPQDTSFSFEPAVNAATY
                     ALTRATIERSVKEGAKTILTGYGGDHVMGGSEAVLADLAGQLKIKALFSHLYPFALHRR
                     LSVPKVLWHSAIAPHLNLGLIKEWTTDRKAEYIYELKKINTFNKQNFFRQISGTKARIF
                     SDRVIAAEFGVDISHPFLDRRLIEFLYSIPGELCWNAGTTKWLLRRTMQNKLPNEVIWR
                     ENKTDHLSLTFQGLRQSWPVLYPAIEEGRVCRFGFIDLKEWRAALELWRQGHLTRDDIW
                     VLLAIEIWLYRLEQKTSVS"
     gene            12840..13280
                     /locus_tag="CZ379_RS16835"
     CDS             12840..13280
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS16835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_110932681.1"
                     /transl_table=11
                     /translation="MIIFSLSISLALILILVITARRQIFQQENALASMMPVREVRNKLY
                     GGFTGFVLCLDFTRYPNTRKMRDFICQHIESEKILIYDISMFSSSDMSMFQGITDYFYP
                     SLGCVKEGILDQDMIVLNRFDSEYKNQIVEFIKHFEKENEHD"
     gene            13273..13698
                     /locus_tag="CZ379_RS16840"
     CDS             13273..13698
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030416 - methylamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018942.5"
                     /locus_tag="CZ379_RS16840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MauE/DoxX family redox-associated membrane
                     protein"
                     /protein_id="WP_199925649.1"
                     /transl_table=11
                     /translation="MINWLGILQWMTAIGMAVIYYKSSTQKLRNAYGFYCIVTGDYKLT
                     NKQKATVLSPFLGAIELITALWLVVPWMQVFGFMMVACLQILFLFVLIPRKGLVLKNGC
                     GCFGLNTPKEITGRDLVNNSAILSVVLIFIGINSLGV"
     gene            13716..14228
                     /locus_tag="CZ379_RS16845"
     CDS             13716..14228
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030416 - methylamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018942.5"
                     /locus_tag="CZ379_RS16845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MauE/DoxX family redox-associated membrane
                     protein"
                     /protein_id="WP_110932683.1"
                     /transl_table=11
                     /translation="MLEITSLLMAYAIAITLLLSGISKIYDIQGTIRSAIAVGILPTNL
                     ARGFGFLLPFAEVILAVILFITSESYLLLAALLLVFVSFVIANAKVMLEKKDLACHCFG
                     RFITGEMGLGTLMHSLILIIYWIPVCIQPTNYTKLLHTIHDPSSIAIIFMGILCLVGTG
                     MISRLID"
     gene            14247..14762
                     /locus_tag="CZ379_RS16850"
     CDS             14247..14762
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS16850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_110932684.1"
                     /transl_table=11
                     /translation="MVQSQLALWMLLSIQTVLLCTLALQFRKQKNGGGLPPGMRIPNIP
                     VETASDTQYLRSIAKENNITFILLVSGGCKFCVAVLKELSKQYNDQMIPIRILYYGKKD
                     ETIDIPTEIPVYQIRKEMTSLLKINKFPFGLILDQKSVILRRDIVSVQQLESWLKAQLE
                     NFPEFTGE"
     gene            14765..16594
                     /locus_tag="CZ379_RS16855"
     CDS             14765..16594
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="CZ379_RS16855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_110932685.1"
                     /transl_table=11
                     /translation="MNQGDIRRLSLDSLRHIKLIFMIGWKAHPRLMSVWIFIMFILAFI
                     PTVQIWLHKTLIDQVSTLSTGQGSIYIVMFSLFIYYGSGFVLVTITEIQKYIYTIVQQD
                     ANMKMKHDLLKKINDVPLQHFEDHAFFNQMTMAQTALNLGCFDFIQYLFQGMRTLLTII
                     SVFGLLAYVSWALPLGLIASTFPGILLLFIAKKKRFRFTLHSTEEGREMDYLYRLLQLK
                     ESAREIRIFQLAEHLISRWKQIQLTFREFQLKNKKQEALGGTFGSMFMTSSAIVVGLLL
                     LWQVKDGAISIGSFVALIASVLTIQGMVGSLGAAVMQLWESLFNLNHYYSFLNKNIETE
                     QGTLSFPKPHFHAIEFQEVSFRYGNHKESIRNVSLQIRQGEKIAIVGENGAGKTTLVQL
                     MLGLYSPTQGRILIGGLDIREIDQTSFLANVTCVFQDFVRYRLSLRDNVGFGQLAEIEN
                     DEKIRDVLENTGLNSLVKQLPKGLETKLSSQFISGQELSGGQWQRVAIARALMKNAEIV
                     ILDEPTAALDPRTEVDIIQQMHQLSNQKTSIIISHRLGPARLCDRIIVMKQGEIIEIGN
                     HKELLSLNGEYAKMYHTQSQWYQDTEIESRRAL"
     gene            16597..17358
                     /locus_tag="CZ379_RS16860"
     CDS             16597..17358
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="CZ379_RS16860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_234405058.1"
                     /transl_table=11
                     /translation="MILEIEKLSKFYTTHSEMTYVIKDINLTISRGEFIVVMGKSGSGK
                     TTLLQLIGALIDPSDGNIRVDGQSLQEISVEPHATQYRREKVGFIFQFFNLIASINAED
                     NVAMPLLLAGVKKKEAYDKARDLLEKVGLLNKRKQYPHTLSGGEQQRIAIARALVQNPC
                     LLLADEPTGNLDSVTTSHILSLLVQLQKHRNQTILLVTHDPQVAAHADRVIFLHDGKLV
                     LDHANDKACDHNKRVSVIVDLQLESQGKVGI"
     gene            17358..19943
                     /locus_tag="CZ379_RS16865"
     CDS             17358..19943
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF014717.5"
                     /locus_tag="CZ379_RS16865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_110932687.1"
                     /transl_table=11
                     /translation="MVILMLARKMLLAKKSRMMYMLVGVMLGTILLTSVVLLGQMLHAS
                     IKKQQFVQFGYTDIMVGYRTAEQGLTPEQIDQITSSTMVQGFAQILAAPKIPGLSPDFY
                     VVGVDNSEIAKSTYKFTQALQPFEIVLTERLAERWGVELHGKTSIPSFPSSQPWVVKEI
                     IPDRYGPDGPLPDYAIFHLQSLQENVGSDVKVNLLLINLVKDHDKQRFSRFVKDNFDPI
                     PDVDIVGDSEEGDKLNSFLVIGYALGVMVVFASGFMMLSSFYITVQQRKKELALLRMIG
                     GSPSQLKLMVCIEGLAIAIIGSFLGSLMGVLLTKLTINWMARYLAIPLFSVSISYEYVA
                     VTAISIALFVFLTSLIPAHKSSRVLPMEFLNEILDENLRPRNTQKWIAVGLLVISLLCA
                     GIGRWGDQESSLHVLFYVVGGLMISSSLYMFTPFWISPVLRILSPLLERIAGIESKIAV
                     QNLIFQRAQSTLAVIIIGLSMTLTIPIVTIYTWIGDNMLKQIESNYISDILVSSNKSMR
                     STVPLEIQEDLQQIPGVKTAIAVSVNRTLILDNYDFSKSNQRWLNLKSSPSPLFKNEHN
                     KPVLNREVANYKLVNIHSLVKELNLQLPQEIELQNAVMITARYAEMLGVRKGDTLEFLT
                     VPSAYKEPYRQVKVTIAAVLDQLYANEDTLLLLDWNNSALTGLDQPNVHSVMLYVDPTQ
                     KALVAQHIKMLQMNKYDEINWSDRSTQLQELSKQMSERILILGATFVLLLIMGLSGMAN
                     HLSAILLTKRREMSILRMISATHGQIRKIIIVQCGLFGMIGIVIGVITGWLITLYFSQI
                     DNGHIYNAIREQVYIVICVVVFTFILSFLLGSKEARMVSESKKSNIQMD"
     gene            20296..20562
                     /locus_tag="CZ379_RS16870"
     CDS             20296..20562
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CZ379_RS16870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_110932688.1"
                     /transl_table=11
                     /translation="MKELEMIIDQSAEEYLKSIINEMIKLFQISEEEAYGRINRFWSGK
                     NLVGDHIMLYHLNENYWANTIYYRKNSYWWLREGEKIEPLPYP"
     misc_feature    complement(21147..21165)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: medium, score: 29.23"
                     /tool="antismash"
     gene            21507..22406
                     /locus_tag="CZ379_RS16885"
     CDS             21507..22406
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003386820.1"
                     /locus_tag="CZ379_RS16885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YitT family protein"
                     /protein_id="WP_110932691.1"
                     /transl_table=11
                     /translation="MAESKPKTSKAGSRKSNVSKPVEFISKILFITIGAIIAGVALELF
                     LVPNAIIDGGITGISLMLTNITGIPLGIFLFVINLPFIFVGYKQVGKKFALASLYGIAV
                     LSLTTGYLHHVEAFTHDKLLAVLFGALLLGVGVGLVLRLGGTTDGAEIVAILISKKINV
                     SVGQIILIINIFIFIAAGFLLGWDSAMYSIFTYYIASKVMDVIVQGLDESKSVTVITKQ
                     YEEVAEAIMSSLGRSTTYLYARGGMNKEDTQVIYCVVSRLELSMLKTVIREIDPGAFIA
                     IETVSDVTGGSFTEEKTH"
ORIGIN
        1 tatcgacact ttccggcaaa ctgatttatg aatttgagca gctgccaggc attacgcatt
       61 cgggcgataa gcttagcatg ctggaagaaa gcaaatccag cgcgggactc cacgctttct
      121 atgaatccaa tgctacagga gattggattg agatgccttt cactgctgag aaaggtacct
      181 atcaactgga tatgagaatc aaacaattta ataatcgggg tatttcacaa gtttacgtca
      241 atggttcagc tattgggcaa cctatagatt tctataatca atctgctaga catatcgata
      301 ctcaggtggg gcaaatcgct ttggatcaga gaccaactca tacgattcgt ttccaactta
      361 ctggcaagaa ttcggcaagt acgaattata ttcttggctt ggatgcgatg tatttaacac
      421 ctgtgaacat tgacacattc gagcctaacg acacgccgga gaccgcaacc gcagtcaatg
      481 ttctccaaac ctatgaatcg tatatttcca gcaagacaga tgtggatttc tataagttca
      541 cggccctgga gggggacacc tatttcttga ccttacaatc tccaagcgac catgaataca
      601 aattagagat actgaatgcc aataaacaac ctgtttcaac gctgagacaa actcagggcg
      661 gggatgaaga ggtttccgtt tatttagcga aaaatgcgtt catatatatc aaagtgactt
      721 ccttgaacgg tgatttcagc tttgagccct atcgttttag aatcacgccg gctcctacga
      781 aacaatatgt ttacgatgat gctaaccggc taactagaac ggaatatgtc caaggattgt
      841 accgttatca aattcaatac gaatatgatc ggaatggaaa tctgttaaag aaaaaagtgg
      901 taagaactat aattactcct taatgaggtg gaaaaaatga aaaaaacgaa aataaatcgc
      961 aagtggcttg tattaccgct ttgtgctggg cttgttgctt ctctaattac tccgggctcc
     1021 attgggtttg ctgaagagtt cgtcggaaag atgaacgaag tgatgtttgg tttgccgtcg
     1081 cgggatcata tgattcaggt tccagatcag gagccacatc ttcaatttga attaaatcat
     1141 gatttggaac cttttacagg gtttcatacg gaagaacagg tcgtgtttga gaatgaagaa
     1201 attcagcctg aagtgaatcc cgcagttgcc cgaacactga cggttgacgt ggaaaagaaa
     1261 gacctgttcc agctaaccga agaacaaatg gaagagctgg ttaccggcgg gtattcgatt
     1321 gaagatgtat accagctgga tcatttagcc aataagctaa tcattgaacc catggaattg
     1381 gcggaacgta gagatgccag tgggctggat tggaatgagt tggaggtgca ggtcactagg
     1441 gaaaatcaac tgaagcagtt atcccaatta tccgaagagc atcctcaggc ctatgcccaa
     1501 cttagtcgtg agacgctaga agatgaggaa caactcatta tattaattgc ttttgacatg
     1561 gggaaaggaa caattgcgga actcatcaag gcctatcaaa cgggcggtga acaggcggtt
     1621 gccaactatc agcctcaacc gaatgcgaaa atgcagaccc aaagcgttaa aagcaacaac
     1681 agcaattcat ctgtcgatgc ggatgttctc aagtccatcc gttcgattgc agaggagaca
     1741 gggatttctg aaagtgaact gatccagcaa taccacgctg ctaaagaagc gagcaaacat
     1801 gctttggcag agaaggagta gcgaaatgag aaaagtcgca gcatttattc gaaattgtat
     1861 cgttgccgta ctggtatttg ttatcgcttc tcaatcaggc gtctccagtg tacatgctca
     1921 gatcgatagt cagcagcttg aaagggtatt gaatggcctg gttacgccca agcttgtgaa
     1981 tgaatccaat aaacctaatc tatcagatcg cagcatggta tccgagaccg ttgatccagc
     2041 ctcaggaaca cttgcgcttt acgaaacgga tgttagtcta cccggaaagg atggcttgga
     2101 tttaacgtta ggacgcatat acaattctaa ccaagccgaa gtaggaacga aacgtgtatc
     2161 tgtgacatcg agcacttctc aacgggcggg atggggatcc ggttattatg tcaccatact
     2221 ctattgggac aaaaatacca acaaatacgg cactcatttt ccaggatatt attctactac
     2281 tactgcagca cacaacatag ctaaccatta tattaaaaat caacctgata gcagccgtgt
     2341 ctacttggat tatgatatgg agtacaagga tgttctctac atccaagtga cctacacgac
     2401 aacgacgaaa atttatcctg atgaaaattc atatagccgt ctaaggtatg atttgggcgg
     2461 tggttggtcc cttgccttcc cgtctttaca aatcgaggga acttatcttc attatcatga
     2521 tggagctgga gcggcttata ccgtaaaatt tgatgcgaat aaccggggga aattggaaga
     2581 ttacagtcga aatgatgttg aactgttaag agataccgga tattcaaacg gtcagatgac
     2641 ttctacctat gtgctcgtcg atcagaataa gaaaaagact tatttcggga gcgacggaag
     2701 actgcttggg attaaggatc ggttcaataa tgagataaag ttcacacata ttaatcgaac
     2761 attgaatggc cggagttatc ctgtaatttc aaaaatagtg gattctattg gtcgaaatgt
     2821 tgattttgcc tatcaaagca atttgactga tcctaacttt gacaatcaaa acatgacgga
     2881 gaatattacg ataacgatta gtcatccttc tacgtcagaa agacgttcta ttgtttatgc
     2941 caaaaaacgt gaggaagtta gtatatttga aaatggttcg ctgatcgggc gcagatatga
     3001 gccgtattta tatcgagtaa ccgatatgaa aggctacagc acttactatg agtattattt
     3061 ggcgtccgaa aaatttaacg caaccagtaa atcgcttaat aattctgccg gcaccgcagt
     3121 ctatttattg caatatgcga tgtatcctca ttcctcttca ttttatgaat atactgtggt
     3181 acctcgaaat tgggggggcc agggcgcata tcaagctttt caagtgacca aaagatggga
     3241 tgggttaaat cgctacaatt atgatgcggc aaatccatcg atgtatgctg agggacctta
     3301 taaccaacgg gattatactt atttcggcga tgtgacagga tatcctacct attatgccga
     3361 ggagtccatt ccggagtcct accgattcgg gtcggaatat gtgaatcagg atggaatcag
     3421 aacaaagtac actttcaatg gcaagaagca attgctaatg accgagcaaa cggctgcgaa
     3481 tggagaaaaa attacagaaa cagtacaagc ctttcacaca gcttataaat ataagccgac
     3541 aaagatcgaa acgaagacaa ctagcggaac cagggagaac aagctttatc aaacatatga
     3601 ttactacgac tggggggatt tgaaaagtac aacacgccca ttaactgctg ctcagttaaa
     3661 tgatacaact caagttcagc agcatacgac aacctatgat tatgatacaa actatagact
     3721 gccgattaaa attgaatatt atcaatcggc tgacaacttg cttactgagc aatttacgta
     3781 tgacgcccag ggaaggctaa aaacagcaca aaatgctaat ggagaaatga caacatatca
     3841 ttttacgcaa gcgagtgacg gcagaaccga agaagtaatc atgccgctag agaatggcaa
     3901 gacggcgaaa acggtctcgc attatagcca aagtggatcc tatcagctat tccctaccac
     3961 aataaaaagc tattatacga atgagtcagg ccagcaagta gaggtgtcgg ttcagcggac
     4021 atataatgtg ctgcttggac tgatgacttc cgagacgaat gcagacaata agacaacaca
     4081 ataccagtat gatgtctacg gaagattgac caaaacgctc tatcccgcga ccaataacca
     4141 aagcggagag cgttatcaaa cggaagaggt ctttgtgtat aacgatcaga ccgtagataa
     4201 cactcctaat tattttgata gtgagaataa atatctgatc acgacgcggg ttgattcgca
     4261 tacgatgacg acgcgtttaa gtgatagtgc cgtcaattac gacaacatta cacacgagtt
     4321 ttacgacgga tttggaaatg cagtccttat tgggcagctg gacaatacaa ctaaccgtca
     4381 tttaattgtc gcgcaatatc attatgatgt tatgactagg cccaattatg tgatagatac
     4441 gagtcacaat gtatccactg ctaaatatga tgcttgggga agagcattcg aatctacaga
     4501 tccgtttgga aatttgtatc gtacggatta tgacatcatt gatcgcaaga gtacctccta
     4561 tatggtggcg gcgagtgata ttgcctcttt ccgtaatagt ccacaggatg gcttgaaacg
     4621 aaacgtatta gaaacgacct ctgatcagtg gggacgaggg atatcctcca aggcattttc
     4681 aaattggccg aatcggacgg caggtgttgt gcaagaagac gttgcttatg atcatttggg
     4741 aaatgtgatt agctatacga atccgaatcg gaacacaaca agctataggt atgataagca
     4801 taatcgctta atatcggtgg tagacgcatt aaaccagacg acttcatatt cgtataacaa
     4861 gctcggacag cttcaatcca tatcacaaag cgaggggagc aaaacctggg caacgacaaa
     4921 aagccatgat gagacaggat ttttgcggac gagtacggat cctgctgcca atcaggatgt
     4981 gttcactcga aacaaactcg gacaaattgc tagccgcaaa gatccgaata acactcttat
     5041 tagctacgct tacgatgaaa ctggccgcaa tatcattaaa gttgctggat caaccacttt
     5101 aaaaaatgta tatcaatatc gtatttttgg ccctttgcgt caagaggaaa tccgtaatgg
     5161 ctccaattat atgacagtgt ataatgatta caatatcttc ggttccttga aatacaaagc
     5221 gaccgtatac gatggagttg ccacggttgt ccgccatgaa tatgatgacc agaatcgatt
     5281 gaagaacgtg gctgacgcct tcgattactt tacacattat tcgtacgata agacgcgaat
     5341 tagccgggta cagaccaacg gtacgtattc attgacgact gccgaaaatg cgaatgccca
     5401 gtacatctac gaaccggacg gcaagctgaa gcgggtgacc tatcccaaac tgacggatgg
     5461 cagtttcctg accagtgatt atgcctatga tggtattggc agactcttga aagtcacgaa
     5521 taagaaaggg acgacgatcc tatccgagta ccaatatcaa tatgatgcca atggcaacat
     5581 caccgccgtg acggatgggg cgggtacgac gagctaccag tatgataagc tggatcggtt
     5641 aattcaagta aaacgccctt ccggtcagac catcgtctat acttacgatg ctagggggaa
     5701 ccgcaagacg ctgaaaggcg acagcctaat tgaagacagc aatgaacaga cgtacacctt
     5761 caacatttgg gatcagctta agagtgtggc gaaagagaat gtgacgaccg agtttgagta
     5821 tgagatgcaa ggactacggc tgtctaagac gaccactaca acaccagccc acgaaagtgg
     5881 aacggctact ccccctacgc cagttacgga gaaagtacgt tacgcgtata acaatagtgg
     5941 ccaagttatt tccgaatctg atgcttcgaa tcgggcgata gcgaattacg tctggggccc
     6001 ggatcggatg ctcgccaaac gggatgtagc cacaaacaag aagtactact atctctataa
     6061 cggccacggt gatgtcgtac agattgtgga cgagaacggc acgaaggtca acagctatca
     6121 gtacgatgaa tggggcaaca tcctggctca ggaagagggc attcgcaact ccttcaaata
     6181 tgctggggag atcttagatc aggagacggg gctatattat ttgcgggcta gatattataa
     6241 tccagagata gggcggtttg taagtaagga tacgtatgag gggaacgtta caaatccgct
     6301 tagtcagaac ttgtatacgt atgtgcataa taatccgttg atttatactg atccaagcgg
     6361 acataaagtt tggctaatac atggtactaa tcttaaaaaa cgaaaaaatc ctgaagcaac
     6421 ctggacacct gaatttattg attatatagg aaatttatat aatgaagatg ttgctactcc
     6481 acgctggtca ggggggaaaa caggaaataa taaggctgct agagagaagg ctgctgaagc
     6541 tatagccgag gatatattaa aatggcaaga aaagaatcct gatgatccca ttagattagt
     6601 aggccacagc cacggtggaa atgttgctat tttggttgct aacatactag gtgagaaaaa
     6661 aataaaagtc gatactgttg taactgttgc aactccagta cgagggtatc aacttaagca
     6721 agaagtagga cagcatcttc atgtgtatag tgatcgagat agcattcaag taaatggggg
     6781 taccccatgg ttgttattaa aggcaggacg gacattttct gcagcagcca atgtgaaaat
     6841 tgatgtagat aaaaaataca ataacattga ggctcattca gcaatgcact caaatgtaga
     6901 tgtgtggaaa caatatatac aatcactttt agcagatttc tatgtaaaac cataattaat
     6961 tcaccgatat ataaggacta cgcttagtag tccttatata tctaataagc ataacaaagg
     7021 ggggatatta ttgttgcttt taataagagg cgtatggata ctagctcttt taattaatct
     7081 atccgctgtt atgtggttta tctttgggac aacagcaaat tttcaacgag gaatggatct
     7141 agtatcaact gtcatttttg tctattttgg aataccatcg atattgttga ttgttttatc
     7201 aatattttta attatcaaag gatggattcc ttcatctcca tggcgtatag ttgctgtttc
     7261 catactaata ttgggcctgc tatccttaag tccaacattg tttaagtacg tagacactag
     7321 tggatggcta gaagagaatg ttacaactga cacattacaa attacatcgg ataatgcgta
     7381 tgagtataac ctcgagataa ttaatttgtt tcaaaggaat agttatgctc ggctacatct
     7441 taaaagtaca tcaacagatg aagaaatacg tattccatta gacatcccag tgaaagagat
     7501 tgttgtactg ttcgaagaga agaattatca tttaattttt ctgaaagcga cttcagaagc
     7561 agatgtttat atattacatc cgacatcaaa actgcccttt cctaatgaaa aatataaaat
     7621 tgatgtaaag aaaaaagaag cagtgaaaat accatgaagt tcactactat actatataaa
     7681 atagatgatt tccactgtta tcaataattt tatactaagc cacatgcgag agtaacaggt
     7741 caagacccta tttagtgaac attgaaaata aagctaggat gcgagctgac gccggtaaag
     7801 tatcggcgtc agcttattta atttccactg tggccgttgt tgattataaa atcgtatgtg
     7861 tatctcttcc aagttgcgga tatgataggg atagagctct tctgttttga gatgcgagaa
     7921 tgacttgaaa aataacaata taaggagaga ggattagttt ggtaactttt ctttatccat
     7981 atgaattaga tggtaattgg gactatgttc gagaaaatgg gatgtgtagc atccttccta
     8041 attttctgaa gtagattttt tcagaaaaga ttacaaacct ttagaattat tctcggatgg
     8101 cttagcgttg gttcttttcc taaattattg gtttggttat attaataaac aaggggaagt
     8161 tgttattcct gcaagtacta aagttggtag ttcctattct gaagaaatgg cttatttcta
     8221 caatcccaca aaatctaaat acggcacatt aagttaaaag gtgaaatttc tattccacct
     8281 cggtatgatt ttaccctttg ttgaggggct tgcatttgtc aaacgaggtg atcaacctaa
     8341 agtgcttgat aagcagggta agaccttata ttattttcca aaggaaatcc agattgactt
     8401 agaaacatat tctaataagt caaagcttat ttcaattaca gatactatga ggagaaatta
     8461 atcctacggc cttcggggca gataattaat gtaagcaagc cagcgcttta atataaggtt
     8521 agctagtcat tcttcttcct gtaaaattat attaatgaaa cacataaaag cttagttctt
     8581 cgtgaagttt tagccgcaat tgagtcattt ttctcaattg ctgtttttta ataatggaac
     8641 gggtcattca ggtagtaacg gcactagaca cgctaaagct agtaaatgat gactaggaat
     8701 gcaaactgaa atttcaaaca aatttccaaa aaaacattac aatatctttg gctccttgga
     8761 tgccttcgat tacttcacgc attatacgta cgataagaag cgaattagcc aggttcagat
     8821 caacggtaca tattcattga cgactgccga aaatgcggat gcccaataca gctacgaacc
     8881 ggacggcaag ctgaagcgaa taacctatcc gaaactaacg gatggcagtt tcctaaccgg
     8941 tgattatgcc tacgatggta agggcagaat cttgaaagtc acgaataaga aaggaatgat
     9001 cctatccgag taccaatatc agcatgatgc caatggcaac atcagcgcag atgttcctga
     9061 cgagaatgct acaaactttg ggcgaacaat tttcgatgcg ggagtaggga aatggtatcc
     9121 agaaagttca tttcatatta attgggatag gactgtaata tcagatgcat acattggttg
     9181 tgcttatgat agtcaatgtg gtggttttgt tggtgcagct atagttgaaa tccctgcagc
     9241 atataatatt gctaagtctg gtggttcaaa aagtactggc tttgtaaaag ggttaataaa
     9301 taaaaaaata actgctaaca ccaaaagtta taaagatata caaaggaaac attaatatct
     9361 attcgcgcgt aatgtaatgt gaacctaagt tggctattaa acgctgtcgc tacaccagac
     9421 gggaagacag atgaagatga attcgagaaa aggctgattg aagtttttag aaatcttgat
     9481 gaaggaaata attgagttta tatgagtaaa aatgaattta agatcatcaa tctaatatat
     9541 acctttattc ctctagcaag ctaccaaaca aagttagaca aagcacagca agaaatacag
     9601 tgactttaag gagttacaaa caaaattcgc agccataagt gcagtaaaca acaattcaaa
     9661 ttagaatatg tcaaatgccc taagctgtca aaaagatact tttatcgaaa cgcgcgtaat
     9721 tatgatcggc ggtcaggctg aaattttcta tggtaagtgc gattattccg aaattgaaac
     9781 tagtcaagta gaaaaggaga aaatcaataa aatacataat acccagaaaa aggtatacaa
     9841 aaatgcagat atttggtaat atatgtacat gatacctttt tgaaggctct ttatgtcata
     9901 ttttctttga ggacttctgc cgaattcgta tgggatagga atgagattga ggcttgaatt
     9961 tgtgtaaagg tgacaaagct gaagtttgga gaggattaag atgtttagaa aagacgatca
    10021 gatttatgaa gctcaagaaa atggagaatt tgttctgctc aatctccgaa cagggcaatt
    10081 ttatgggcta aatcatattg ggagcgaatt ttggaaactc ttatttacta ccgaaatgag
    10141 tgaaattcac caatattttg aaaaggcata taaagccgat ccggtcattg tgcgtcgcga
    10201 cctcgaggcc ctattaagtg atctcatccg gaacgggctg gtacatagat catgaaaaga
    10261 tattttcaat ttatacaagt cgcgtttgct cttattcgat ttcaaatcga acttcgaata
    10321 tacggttttc aaaagatttt ccctaaatat gtcgaacgat atccgatacc caagcactca
    10381 gaaaatgaac gaaatcatat tggtcaaatg aatcatttac tacgtacaat cgacatggca
    10441 tgcgcactgg ctccatttaa agcagaatgt ttacatcggt catttctcgg ttttcgattt
    10501 gttaggacaa aatgctctat acctgtagat ctagtgatcg gagtaaaaaa atttccattc
    10561 acctcacacg catggcttgt tcttaatgat aaaaacatta atgaagccga gggatacaca
    10621 aaacaattta ttatcattct aagttcgaaa ggattgaaat aatatacgat gcgatggttc
    10681 tcaggagtca taaaacttga tcattctgag ctttcatttg aggaaattgg aaggataaat
    10741 cgtaatacat cctttaatta taacgtctat aaacatcaaa ttattcaaaa atcgttggca
    10801 cttttcagta tcgattcttc ctatgaacat aatcccataa cacacaaaga caattgttat
    10861 tttgttggcg atgtacggct tgacaataga aaagagcttt taactctgtt gcccttttta
    10921 ggagcagaca tatctgatga acaacttatt ttacacttgt ttcaagaaaa gggacccgat
    10981 gtattttcca tattgctcgg agaattttca tttttgatct gggatacatc tcgttatcaa
    11041 gcaatattcg ttcgcgatca gcttggaata aagacattat tttggtctct tcaagaaacg
    11101 acactttact ttgctagtga cattttttta atggaatctt gtatacggtt acagcgtatt
    11161 aacgatgaat atttttttga tttctataag tccaatgcaa gcgccgacaa tgatatcaca
    11221 ccatttaaag atttatttcg gattaggagc ggaacgaggg tattggttga tactagagga
    11281 gcaaattctc aacgctattg gagtatagcg aatgtcaatc aatcgattaa ctatcgagat
    11341 ttgagtgaat acatcgagca cttattccat ctattagcgg agagcgttca atatcggctc
    11401 aattctacac atcccaatgc tgtcttaatg agtggcgggt tggattcgac atctgttttt
    11461 gcaattgcac aacatctatc caagttcaat tccggttata agacttttgc ggtaagtgga
    11521 gtctttaatc ttcataagtc aagtgatgaa agggaatata ttcatcctgt tcttcaacaa
    11581 tacgaggtcg aaccgcgctt tgaagtttgc gacgactatg gagtatttta taattttcct
    11641 caagacacat cgttttcatt tgaacctgct gtcaacgccg cgacatatgc cttgactaga
    11701 gcaacaattg agcggagcgt caaggaagga gcaaagacaa tcctgactgg ttatggtggt
    11761 gaccatgtta tgggaggatc agaagcagtt ctcgcagatc tagctggaca actaaaaata
    11821 aaagccttgt tcagtcattt atatccgttc gcgcttcata gacggttgtc tgtcccgaaa
    11881 gtgctctggc atagtgcgat tgctcctcat cttaatctcg gattaataaa agagtggacg
    11941 accgatcgaa aagcagaata tatctatgag ctaaaaaaaa taaatacgtt taataaacaa
    12001 aatttttttc gtcaaatttc gggtacaaaa gcacgcattt tttctgatcg agttatcgca
    12061 gcggaatttg gcgttgatat tagccatcca tttcttgatc ggcgattaat tgaattccta
    12121 tattcgattc cgggagagct gtgctggaat gccggaacga cgaagtggct acttaggcgt
    12181 acgatgcaga acaaattgcc taatgaagtg atttggaggg aaaacaaaac cgatcatctc
    12241 tcgctaacct ttcaaggttt gcggcagagt tggccggttt tgtatcccgc tattgaagaa
    12301 ggaagagtat gtcgatttgg atttatcgac ttgaaagaat ggcgagcagc attagagcta
    12361 tggagacaag gccatttgac aagagatgac atatgggttt tattggcgat cgagatttgg
    12421 ctgtataggc ttgaacaaaa aacgagtgtg tcatgatctg aagattaaat atcggtgtgc
    12481 gtacccgcaa agggagttaa aatacaaatt atttgggagg aattctaatg aattattcaa
    12541 ctccaatgct tactgtttac ggagattcaa gcaatttgat caaaggtgat tgcgactggg
    12601 gcactgaaaa ttggtgggca gacaaaacgg gatattataa atatacgtac tccgactgca
    12661 ttatgacggt aacttgcgcc accattggtg attgtcattg tgggtcaact tccatgtgta
    12721 caacgtctca accaagggat caatgcagtt ctgataacga ttgctaatct atatcattaa
    12781 gtaatctaat tgcaggtgcg cacattcttt tttcactgct atcggaagtg agtgattaga
    12841 tgataatatt ttctttatcc attagcttag cacttatatt gatcctcgtg ataaccgcta
    12901 ggagacagat atttcagcaa gaaaatgctt tagcgagcat gatgcctgtt agagaagtta
    12961 ggaataaatt gtatggaggg tttactggct ttgttttatg tcttgatttt acgcgttatc
    13021 cgaatactcg gaagatgaga gatttcattt gccaacatat tgagagcgaa aagattctta
    13081 tttatgacat ttctatgttt agctctagcg atatgtcaat gtttcaaggg attactgatt
    13141 atttttatcc gtcacttgga tgcgttaaag aagggatcct ggatcaggat atgattgttc
    13201 taaacagatt tgactctgaa tataaaaatc aaatcgtaga gtttattaaa cattttgaaa
    13261 aggaaaatga gcatgattaa ctggctgggt atcctccaat ggatgactgc gatcggaatg
    13321 gcagttatct actataaaag cagcacacaa aaattacgaa atgcgtatgg cttttactgt
    13381 atcgttacag gggactataa attgacaaac aagcaaaaag caaccgtact ttctcccttt
    13441 cttggtgcaa ttgaactcat cactgccctt tggctggttg taccttggat gcaggtgttt
    13501 ggcttcatga tggttgcgtg tttgcagatc ctatttctat ttgtgttgat accaaggaaa
    13561 gggcttgtac tcaagaatgg atgtggatgt tttggcttaa acactcctaa agagattaca
    13621 ggtcgtgatc ttgttaataa cagtgcgata ttatctgttg tattaatatt tatcggtatt
    13681 aattcgttgg gagtatgaaa ttgtaggagg gccgaatgtt ggaaattact tcgcttttga
    13741 tggcttatgc aattgcgatt acactccttt tgtctggtat tagtaagatt tacgatattc
    13801 aaggtacgat aagaagtgca attgccgttg ggattttacc gactaatctt gcccgtggtt
    13861 ttggcttctt actgccgttt gcggaagtca tactagcggt aatcttattt attacttcag
    13921 aatcgtatct gttgctcgct gccttgcttc ttgtgtttgt ctcgtttgta attgcgaatg
    13981 caaaagtaat gcttgagaaa aaagacctcg cctgccattg ttttggaaga tttataacag
    14041 gtgagatggg attaggaact ttgatgcatt cgctaatctt aatcatctat tggattcctg
    14101 tttgcataca gcctacaaat tatactaaac tgcttcacac cattcatgat cctagttcaa
    14161 tagctatcat ttttatggga attctttgtt tggttggaac tggaatgatt tctcgtctca
    14221 tcgattaaat gaggaggtta gaatctttgg tgcaaagtca acttgctctt tggatgttat
    14281 tgagtattca aacagtgctc ctatgtaccc tggctttaca atttcgcaaa caaaaaaacg
    14341 gggggggatt gccccccggc atgcgcattc cgaatattcc agttgaaacg gcaagcgaca
    14401 cacaatactt acgaagcatt gctaaggaaa ataatattac ttttattttg ctcgtctcgg
    14461 gcgggtgtaa attttgtgtg gccgtactta aagaactttc aaaacagtat aacgatcaaa
    14521 tgattccaat tcgaattctt tattatggga aaaaagatga aacgatagat attcctacag
    14581 aaattcctgt ataccagatc agaaaagaga tgactagtct tttaaaaatt aataaatttc
    14641 cattcggttt aatattagat cagaaatcag ttattttgcg ccgggatatt gtatctgttc
    14701 aacaattaga gtcttggcta aaagcacagc tagaaaactt ccctgaattt acgggtgaat
    14761 agggatgaac cagggggata tacgtcgctt atctttggat tcattacggc atattaaatt
    14821 aatatttatg atcggatgga aagcgcatcc tagattgatg tctgtatgga tcttcatcat
    14881 gtttattttg gcctttatac ctactgttca aatctggctt cataaaaccc tgattgatca
    14941 agtttcgact ttatcaacag gacaagggtc tatttacatc gttatgtttt ctttatttat
    15001 ttactatggc tcaggattcg tgttggttac cataacagaa atccaaaaat acatttacac
    15061 aattgttcag caagatgcca acatgaagat gaaacatgac ttgttgaaaa agattaacga
    15121 cgtccctctt caacacttcg aagatcatgc atttttcaat caaatgacga tggctcaaac
    15181 tgcattaaat ttgggatgtt ttgatttcat acagtacttg tttcaaggga tgagaactct
    15241 actaacaatt ataagtgtat ttggactttt agcatacgtc agttgggctc ttcccttggg
    15301 attaattgcg tctacgtttc ccgggattct cttactattt attgcaaaaa agaaacgttt
    15361 ccgttttacg cttcacagta cggaagaagg acgtgaaatg gattatttgt accgattatt
    15421 gcagcttaaa gaatcagcgc gtgaaataag aatctttcaa cttgcagaac acctgatatc
    15481 gcggtggaaa caaattcagt taacctttcg agagttccaa ctaaagaata aaaagcaaga
    15541 agctctcggt ggtacttttg gttcgatgtt tatgacatcc tctgcgattg ttgtgggttt
    15601 gttattactt tggcaagtaa aagatggggc gattagtatt ggtagttttg tagcattaat
    15661 tgcgtcagta ttaaccattc agggtatggt gggcagtttg ggggcagcgg tgatgcaact
    15721 gtgggagagc ctgtttaatc taaatcatta ttattcattt ctgaacaaga atatcgaaac
    15781 ggagcaggga actctttctt ttccaaagcc tcattttcac gcaatagaat tccaagaagt
    15841 tagtttccga tatggaaacc ataaagagag tattcggaat gtttcactcc aaattaggca
    15901 aggtgaaaaa attgctatcg taggggagaa cggtgcgggt aaaacaacat tagtccaact
    15961 gatgctaggc ctctattctc caacacaggg gcggatatta attggcgggc tagatatccg
    16021 tgaaatcgat caaacttctt tcctagcaaa tgtcacttgc gtatttcagg attttgtacg
    16081 ctaccgtcta tcgttacgcg acaatgtcgg tttcgggcaa cttgcagaaa tcgaaaatga
    16141 tgaaaaaatt agagatgtgc ttgaaaatac aggtttaaat tcattagtaa aacaattacc
    16201 gaagggtctg gaaacgaaat taagcagtca gttcatttca ggacaagaac tttcaggggg
    16261 acaatggcag cgagtagcga tagctagagc tctaatgaaa aatgcagaga tcgttatact
    16321 agatgaaccg acagctgcac tagatccgcg taccgaagta gacatcatac aacaaatgca
    16381 ccaactatcg aatcagaaaa caagtattat catttcgcac cgacttggtc cagctcgatt
    16441 atgcgatcgt ataatagtta tgaagcaagg tgaaataatt gaaattggaa accataagga
    16501 attgctttcg ttaaacgggg agtatgctaa aatgtaccac acccaatcgc aatggtatca
    16561 agacaccgaa atcgaatcga ggcgagcact ttgactgtga ttctggaaat agaaaaactc
    16621 agcaaattct atacaacgca ttcagaaatg acgtatgtca ttaaggatat taacctaact
    16681 atatcgcgtg gagaattcat tgtcgtcatg gggaaaagcg gctctggtaa aacaacttta
    16741 ctacaactta tcggagcatt gattgatccg tctgatggta atatacgagt ggatggtcaa
    16801 tctttgcaag agatttccgt tgaaccacat gccacacaat accgaagaga aaaagtcgga
    16861 ttcatattcc agttttttaa tctcattgct tcgattaatg ccgaagacaa tgttgctatg
    16921 cccttgttgc tggcaggcgt gaagaagaaa gaggcttatg ataaagcgag agatctgctt
    16981 gagaaagtag gtttactcaa caaaagaaaa caataccccc acactttatc gggtggggag
    17041 cagcaacgta tcgcgatcgc gagagcactc gtgcaaaatc cttgcctact gcttgctgat
    17101 gaaccaacag gaaatttgga ttcagtaacg acctctcata ttttgtctct gctggttcaa
    17161 cttcaaaaac atcgtaatca gaccattttg ttagttactc acgatcctca agtcgctgct
    17221 catgcggatc gggtcatttt tttacacgat ggcaaactgg ttcttgatca tgctaatgat
    17281 aaggcatgtg accacaataa gcgagtttcg gttatcgtcg atcttcaact tgaatcgcaa
    17341 ggaaaggttg gtatctgatg gttattctga tgctagcccg gaagatgctt cttgcgaaaa
    17401 agagcagaat gatgtatatg ctcgtcggcg taatgttagg tacgattctt ttaactagtg
    17461 tagtgctctt gggtcagatg cttcatgctt caataaaaaa acaacagttt gttcaatttg
    17521 gatatacaga tattatggtg ggatatagga ctgctgaaca aggacttacc ccagaacaaa
    17581 tagatcaaat tacaagcagt acgatggttc aaggctttgc gcaaatattg gcggcgccta
    17641 agattcccgg gctttctcct gatttttatg ttgttggggt tgataattcc gaaattgcga
    17701 aatcaaccta taaatttacg caagccctgc agccctttga aattgtgttg accgagaggc
    17761 ttgccgaacg ttggggtgtc gaattacacg gcaaaacatc cataccgtca tttccatctt
    17821 cacagccctg ggtggtaaag gaaattattc ctgatcgtta cggaccagac ggcccgttgc
    17881 cggattatgc catttttcat ctgcaatccc tgcaagagaa tgtaggaagc gacgtaaaag
    17941 ttaatcttct tttaataaat ttagtcaaag atcatgataa gcaaaggttt tcgcggtttg
    18001 tgaaggataa ctttgatccc ataccggatg tggatatcgt aggtgactct gaagagggag
    18061 ataaattaaa tagttttctc gtcatcggat atgcattagg ggttatggtt gtatttgcta
    18121 gtggttttat gatgctgagt agtttctaca ttactgttca acagagaaaa aaagagttag
    18181 ctcttctacg tatgatcggt ggaagtccga gtcaattgaa gttgatggtc tgtatagagg
    18241 ggttggcgat tgccattatc gggtcatttc tcggctcgct tatgggtgta ttattaacaa
    18301 agttaactat aaactggatg gctcgatatc ttgcgatccc attattttca gtgtcaattt
    18361 catatgagta cgttgcggtc actgcaataa gcatcgcttt atttgttttt ttaacttcct
    18421 tgattcctgc ccataaatcc tcaagagttt tgccaatgga attccttaat gagatacttg
    18481 atgaaaattt gcgtcctcgg aatactcaga aatggatagc ggtcggatta ttggtgatta
    18541 gtcttctttg cgcaggtata ggcagatggg gggatcagga aagttccttg catgttctgt
    18601 tctatgtagt aggaggatta atgatctcca gctcccttta tatgttcact cccttttgga
    18661 tatcacctgt tttgcgcata ttgtccccgc tccttgaacg aatagcaggc atagaatcca
    18721 aaattgctgt tcaaaatctg atttttcaac gagcccaaag tacattggct gttattatca
    18781 ttggtttatc catgacattg actattccga ttgtcactat ttatacatgg attggagata
    18841 acatgttgaa gcaaatagag tcaaattaca tctctgatat tttagtatcg agcaataaaa
    18901 gcatgcgttc cactgttccg ttggaaatac aagaagattt gcaacaaata ccaggtgtga
    18961 aaacggctat tgcggttagc gtcaatcgga cattaattct ggataattat gatttctcaa
    19021 agagcaatca gagatggttg aatttaaagt catctccttc tccacttttt aaaaatgaac
    19081 acaataaacc tgttttgaat cgagaagtgg cgaactataa attagtaaat atccattctc
    19141 tcgtcaagga acttaatctg caattgccac aagaaatcga actacaaaat gcggtaatga
    19201 taacagcgcg ttacgccgaa atgttgggtg ttaggaaggg ggatactttg gagtttttaa
    19261 ccgttccttc agcttataaa gaaccttacc gccaggtgaa agttacgatt gcagcagtac
    19321 tagatcagtt gtatgcaaac gaagacacgc tgctgctttt ggattggaac aactctgcgc
    19381 tcacaggact ggatcaaccc aatgtgcata gtgtcatgct atacgtcgat ccgacccaga
    19441 aagcgcttgt ggctcagcat ataaagatgc ttcaaatgaa taaatatgac gaaattaatt
    19501 ggagcgacag atctactcag ttgcaggagc tgtcaaagca aatgtccgag cgcattttga
    19561 tattgggagc gacttttgtg ttgttgctga taatgggact gagcgggatg gctaatcatc
    19621 tatcggccat cctcctgact aaacgtcgtg aaatgtcaat acttcgtatg ataagtgcaa
    19681 cccacggtca aattcggaag attattatcg ttcaatgtgg attatttggc atgataggaa
    19741 ttgtcatcgg agttatcacg gggtggctca tcactttata cttttcacag atagacaatg
    19801 gtcacattta taatgctata agagaacaag tatatattgt aatatgtgtt gtggttttta
    19861 cttttatctt atcgttccta ttaggaagca aagaagccag aatggtttct gagtccaaga
    19921 agtccaacat tcaaatggat tagtaaacag cttcaccgat ggttctccct tggtcaagac
    19981 cccatttagt ggacattgaa aaaacaccta ggctgtaaac tggcgacggc aatctgccgg
    20041 cgtcatgttg atttaatttg cgttacggcc gtaatgggaa aatattcact cctactaata
    20101 aagattggga aaacttcatt catatgatta tgtagaagat ccgatgcttg gtaatacagg
    20161 gaggttgaaa ggcaaaggag atcctaaacc ttaggggcat caaatgagta taaactcatc
    20221 aaaaatggca aaatggttat ttgaagatat acaaccagtc atattacttc caggttatgg
    20281 aggaaaaaaa gagggttgaa agagctagaa atgataatag atcaaagtgc tgaagaatat
    20341 ttaaaatcta ttattaatga aatgattaaa ttatttcaaa tttccgagga agaagcatac
    20401 ggacgaatca atagattttg gtctggaaag aatctagttg gtgaccatat catgctttac
    20461 catcttaatg aaaattattg ggcaaacacg atttattata ggaaaaactc gtactggtgg
    20521 ttacgagaag gtgaaaaaat agaaccttta ccgtacccat aagaatggat cacatggagt
    20581 aacataactc catgtggttt tctaaaagta tattctattg ctactactga ttggttcaat
    20641 gcttctgtat aagttggtgc aactactata aatactgtga ggaagtattt aaaccacaat
    20701 gcgtttaatt ctcgaaatgt gattagctat acgaatccga gtcggaacac aacaagctat
    20761 cgatatgata agcttaaccg cttaatatct gttgtggacg cttttaaacc agaggacttc
    20821 ttattcgtat aacaagctca aacagcttca atccacgtac aaagcgaagg cagcaaaacc
    20881 tgggtaacga caaaaaacta tgatgagaca ggatttttgc ggacgattta cggatcctgc
    20941 tgccaatcag gatgctttca ctcgaaataa actaggacaa attgctagcc caaagatccg
    21001 aataacgctt attagctatg cttacgatga ggttggctgg aatatcatta aaaatgtagg
    21061 atcaacaaca gtaaaaatgt ctaccaatcg tatatttggc ccgccgcgtc aagaggaagt
    21121 tcgtaatggc tcaaactaca tgacggtgta taatgtttac aatattttgg ttctttgaaa
    21181 tacaaggcta ccgtatacga tggagtagcc acagttggtt gtccggcatg aatgtgatga
    21241 ccaaaatcga ttgaagaacg tagcggacgc atgagattat ttcacgcatt atacgtaaga
    21301 tcgcgaaagc aaccactggg atttcacgaa tacgctctat tgggacagta gatttaggaa
    21361 tcctggtatc aataagtggt agcttcctag ccagtgatta ttcacggact aggcagtttc
    21421 agaccaactg ctcgctctcc atttgatttt catttaaaat ttcattaaat tatttatatg
    21481 tcaaatttaa tgaaagggtt gaagtgatgg cagaaagcaa gccaaaaaca agtaaggcag
    21541 gtagtagaaa gtcgaatgta agcaaaccag tggaatttat ttcaaagatt ttatttatta
    21601 caatcggagc gattatagct ggggttgctt tggaattatt cctcgtgccc aatgcgatta
    21661 tcgatggtgg aataacgggg atatcgctga tgttaacgaa tattacaggc attcctttag
    21721 ggatcttcct ctttgtgatc aaccttccat ttatatttgt cggctataag caggtaggca
    21781 aaaagttcgc cctcgcttca ctttatggta ttgctgtact ctctttaacg acggggtatt
    21841 tgcaccacgt ggaggctttt acgcacgata aattactcgc tgtactattc ggtgctcttc
    21901 ttcttggtgt aggagtcggg ttagtgctaa ggcttggggg aacgacggat ggagcggaga
    21961 tcgtagctat tttaatttcg aaaaaaataa atgtttccgt gggtcagatc attctcatca
    22021 ttaacatttt tatttttatc gctgcaggct tcttgcttgg ctgggattcg gcgatgtatt
    22081 cgatttttac ttactatatt gcctctaagg taatggatgt tattgtacaa ggtctcgatg
    22141 agtcgaagtc agtcacggtc attacgaagc aatatgagga agtagcagaa gcgattatga
    22201 gcagtctggg gagaagtacg acctacttgt atgctagagg cggtatgaac aaagaagata
    22261 ctcaggtcat ttactgcgta gtcagtcggc tggaactgtc catgctaaag acggtcattc
    22321 gcgaaattga tcctggagcg ttcattgcga ttgagaccgt gtctgatgtt acgggcggta
    22381 gctttacaga ggaaaaaacg cattgatgtg ttaagggagg ctgcagccat gcacctgtca
    22441 acggggaggg tatggg
//
