LOCUS       NZ_FPAT01000004        20201 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Actinopolyspora righensis strain DSM 45501, whole genome shotgun
            sequence.
ACCESSION   NZ_FPAT01000004
VERSION     NZ_FPAT01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinopolyspora righensis
  ORGANISM  Actinopolyspora righensis
            Bacteria; Actinomycetota; Actinomycetes; Actinopolysporales;
            Actinopolysporaceae; Actinopolyspora; Actinopolyspora alba group.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900116555.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,474
            CDSs (total)                      :: 4,407
            Genes (coding)                    :: 4,334
            CDSs (with protein)               :: 4,334
            Genes (RNA)                       :: 67
            rRNAs                             :: 5, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 27 of 73
            Pseudo Genes (incomplete)         :: 61 of 73
            Pseudo Genes (internal stop)      :: 12 of 73
            Pseudo Genes (multiple problems)  :: 20 of 73
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:10:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 162483
            Orig. end                         :: 182684
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FPAT01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20201
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20201
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20201
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10201](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10201)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(676..1377)
                     /locus_tag="BM394_RS23310"
                     /old_locus_tag="SAMN04487904_104154"
     CDS             complement(676..1377)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017976888.1"
                     /locus_tag="BM394_RS23310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104154"
                     /product="NADH-quinone oxidoreductase subunit B"
                     /protein_id="WP_092976665.1"
                     /transl_table=11
                     /translation="MGLEESLPNGILLANVEKLVNWTRKTSMWPATFGLACCAIEMMTV
                     GGSRYDIARFGMERFSATPRQADLMIVAGRVTNKMAPVLRQIYDQMPEPRWVLAMGVCA
                     SSGGMFNNYAVVQGVDHVVPVDMYLPGCPPRPEMLLDAILKLHAKVMDEPINGKRAAEQ
                     VEQGHRTELPASSEKYAPRSGSKRRMAERQQDAQRREMGAEGELGAAGIESLPPGDSRG
                     RAEPNETTAGR"
     gene            complement(1471..1836)
                     /locus_tag="BM394_RS09110"
                     /old_locus_tag="SAMN04487904_104155"
     CDS             complement(1471..1836)
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013677598.1"
                     /locus_tag="BM394_RS09110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104155"
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="WP_092626373.1"
                     /transl_table=11
                     /translation="MLDPYIPLVLMFALAFGFAAFSVAIAPLVGPRRYNKAKLDAYECG
                     IEPSPQPVGGGGRMPVAYYLTAMMFILFDIEMVFLFPYAVSADALGLYGVVAVILFILT
                     FGFADLYVWRRGGFDWN"
     misc_feature    complement(1932..1950)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 26.01"
                     /tool="antismash"
     gene            complement(1996..3294)
                     /locus_tag="BM394_RS09115"
                     /old_locus_tag="SAMN04487904_104156"
     CDS             complement(1996..3294)
                     /GO_function="GO:0045550 - geranylgeranyl reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015995 - chlorophyll biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0030494 - bacteriochlorophyll biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017976890.1"
                     /locus_tag="BM394_RS09115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104156"
                     /product="geranylgeranyl reductase family protein"
                     /protein_id="WP_092976668.1"
                     /sec_met_domain="Trp_halogenase (E-value: 6.8e-07,
                     bitscore: 23.1, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 6.8e-08, bitscore: 27.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTPIRGRATDDAEVIVVGAGPAGATAATYLAKAGLDVLVLEKS
                     AFPREKVCGDGITPRGVKELIDLGVDTRPEAGWLHNRGLRVVGGGVRLEMDWPELAEYP
                     PYGVVRPRNDFDDLLIRHAQRAGARLVQRTSVTEAITDERTGRITGVHAKSGPERAEVS
                     YRAPLVISCEGVSGRLALSMGLQRREDRPMGVAVRRYYESPRADDDYLESHVELWNNSN
                     PKGAELLPGYGWIFGMGDGTVNVGLGVLSTSKAYGKTDYRALLRTWLDGTPEEWGLREA
                     NATGRIGGAALPMGFNRMPHYSSGLLLVGDSGGMVNPFNGEGIAYAMEAARLAAECVIQ
                     ARSRTDAAARERALARYPGAVAESLGGYFRMGNLFSKIIGHPTVMRTATKYGLPRESLM
                     RFVLKLLANLYDSRGGDAVDRVISTTTRLTPSA"
     misc_feature    3395..3410
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            complement(3832..4521)
                     /locus_tag="BM394_RS09120"
                     /old_locus_tag="SAMN04487904_104157"
     CDS             complement(3832..4521)
                     /EC_number="2.1.1.163"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019852716.1"
                     /locus_tag="BM394_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104157"
                     /product="demethylmenaquinone methyltransferase"
                     /protein_id="WP_092976671.1"
                     /transl_table=11
                     /translation="MSRAGLDRNPRAVAAMFDGVARGYDRTNTVLSFGLDRHWRDATRR
                     ALAPAPEERILDLAAGTGVSTAEFSRSGAYCVAADFSLGMLAAGEHRELSMVAADALRL
                     PFADGAFDGVAMLFGLRNLADTEAGLREMARVVRPGGRLVICEFSTPTNRPLRAAYRNL
                     ALRAVPPVARTVASNPDAYVYLAESILAWPDQRELAATIARSGWSEVAWRDLTGGIVAL
                     HHARKPY"
     gene            4983..5822
                     /locus_tag="BM394_RS09125"
                     /old_locus_tag="SAMN04487904_104158"
     CDS             4983..5822
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017976892.1"
                     /locus_tag="BM394_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104158"
                     /product="inositol monophosphatase"
                     /protein_id="WP_092976674.1"
                     /transl_table=11
                     /translation="MSVSPPPKTGRAEQALISRALETAGRLANEAADVITATAGHDTPP
                     SEPDSPFDWVTDVGRTLERHTRRILAEHFPGIPVYGEEFDAAALGGGQGGFRWVVDPVD
                     GTANYVAGVPWCAYSLAMLDAQGPVVGVVADPYRAQIYAAARDRGMRANGKPVRLTEAR
                     SPRASIVCTEFTRYGPWRGMDRFITNAAADHVGVRVLGSPALAITQVALGQAVAAVLPS
                     YGEWDVAGALALAVESGANVLDSYGRPASLPHDGLLVAAPGITETAFGWWWHASGAG"
     gene            complement(5838..6482)
                     /locus_tag="BM394_RS09130"
                     /old_locus_tag="SAMN04487904_104159"
     CDS             complement(5838..6482)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM394_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487904_104159"
                     /product="hypothetical protein"
                     /protein_id="WP_092976676.1"
                     /transl_table=11
                     /translation="MGGFWTHLIVALAAGVLGVLLGVLARRSSSAPPVPEEPPKTTSGT
                     STDARGGLEHALTEHRDAWLCELNRCEQAVHRAVRAADTVSSLPVRRGLRQVVYRMDAE
                     LPTVRTLVQLARELDAGDSTVATADSTRRVALRRIQGGVVMAVSRFTELGDQLAGVVAE
                     LAAGADQEHAQRRIAALRERFPLLPAMSAILEGRAGSGGTPETPSLVRARV"
     misc_feature    complement(6645..6654)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     gene            complement(6716..7666)
                     /gene="paaC"
                     /locus_tag="BM394_RS09135"
                     /old_locus_tag="SAMN04487904_104160"
     CDS             complement(6716..7666)
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019852713.1"
                     /locus_tag="BM394_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104160"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaC"
                     /protein_id="WP_092976679.1"
                     /transl_table=11
                     /translation="MVTSGIGDAPRWFPERRGAREGGGTATPESISNPLGEQQRWTVRA
                     AGTPLTSTDRGVPDDVSAADLSVYCMMLGDDALVLARRQVGWCQHSPDLEEDCVQVGML
                     LESLGHARELLHRAATVEDSGRDENLLAHERGVEEFRNVRLVELDCGPGAGGDFAVSIA
                     RLMVCAAWRTALFGKLVASRDPVLSELARVALPEVRGHRDHAAQWVIRLGDGTSASRER
                     MSTGLARVWPMTGELFVPHPVERRLADLGFAVDPAGLRTEVAALLDEVLSVARLEPPDA
                     RVFHDDVEPLGRTGVHTTALEFLLAEMRQYETVEA"
     gene            complement(7833..8327)
                     /locus_tag="BM394_RS09140"
                     /old_locus_tag="SAMN04487904_104161"
     CDS             complement(7833..8327)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019852712.1"
                     /locus_tag="BM394_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104161"
                     /product="DUF3592 domain-containing protein"
                     /protein_id="WP_245780068.1"
                     /transl_table=11
                     /translation="MTGETQSERTVGTAEPNSADNRSGTRWFPRGFRRLAPSLVLAVGG
                     FFTALGLALLLACHIDDRSIEQDMGTASAEVVEKSYLRTVVRFNTDSGRVYTPPNGVLY
                     PVGLQEGQLVSVEFDRGNPDLVRVAGRNMSVALLPVGSALAVLWAIVLPAYWLTRRTVR
                     A"
     gene            8744..9958
                     /locus_tag="BM394_RS09145"
                     /old_locus_tag="SAMN04487904_104162"
     CDS             8744..9958
                     /EC_number="5.4.4.2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008909 - isochorismate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017976896.1"
                     /locus_tag="BM394_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104162"
                     /product="isochorismate synthase"
                     /protein_id="WP_245780069.1"
                     /transl_table=11
                     /translation="MDLLPEGISPDSGPLCWTRHGEGVVGWGEALRIETEREERFVAAD
                     ERWQRLAARMEVDDEVRLPGTGPVAFASIAFGDDPGSSVLIVPEVVLGQRGGVRWITTI
                     GEHDRRLSRAAPARAPGTIRYSDGEFPTTRYRQAVAEAVRRMRGSTELSKVVLAHDLLA
                     TTSEPLNSRYLLGNLGRRYPGCWTFAVDGLVGATPELLLQRNGNEVSSRVLAGTAWPHE
                     GRTQRQLMSELLGSAKNRGEHTYAVRSLADGLEPFCKELDVPTTPEVLRLRNVMHLASD
                     VSGQLDPMLAQNGHAGLLRLVQSVHPTAAVGGTPTAGAIELIDELEEMNRERYAGPVGW
                     VDADGNGEFGIALRCARITWHSGEGSRARLFAGCGVVPDSDPDTEVTEAEAKLLPVREA
                     LEGVR"
     misc_feature    9341..9343
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..10201)
                     /locus_tag="BM394_RS09150"
                     /old_locus_tag="SAMN04487904_104163"
     CDS             complement(10001..10201)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017976899.1"
                     /locus_tag="BM394_RS09150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104163"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_092976685.1"
                     /sec_met_domain="PF05402 (E-value: 5.3e-07, bitscore: 24.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.6e-12,
                     bitscore: 40.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLHDEESGQLNTTGARVLRDLLNGEDPERVTEKLIIAYRADPGA
                     AADDVNAVLRKLRAACLADHE"
     aSDomain        complement(10010..10174)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BM394_RS09150_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.20E-13"
                     /identifier="RREFam002.1"
                     /label="BM394_RS09150"
                     /locus_tag="BM394_RS09150"
                     /protein_end="64"
                     /protein_start="9"
                     /score="40.5"
                     /tool="antismash"
                     /translation="QLNTTGARVLRDLLNGEDPERVTEKLIIAYRADPGAAADDVNAVL
                     RKLRAACLAD"
     gene            complement(10426..11946)
                     /locus_tag="BM394_RS09155"
                     /old_locus_tag="SAMN04487904_104164"
     CDS             complement(10426..11946)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012795826.1"
                     /locus_tag="BM394_RS09155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104164"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_092976688.1"
                     /transl_table=11
                     /translation="MLRRRALRTAVATCAATVVLAAPALAGTGGAGAPGVGDSYYPEAG
                     NGGYDVSHYDIRLRYQPENDLLRGTTTIVAEPTEDLSSFNLDFALEIRSVRVNGAPARV
                     ERQGATEVTVTPKRALPEGSLATFVVSYADKPSTVEVDGQTPWKRTENGAVAVGQPLIS
                     EWWFPASDHPSDKASFDISVAVPNGTEVLSNGRMTARIRQGDWTRWNWRMPSPSATYLA
                     FLAIGQYDVHSKKGAFDQPMITAYADGLGDIKGPAEASLERTPEILEFLSEIVGPYPFE
                     TQGGVVPAEGLGFALENQTRPVYSPNFFRIGSNTSVVTHELAHQWFGDSVALDDWSSIW
                     LNEGFASYAEWLWAEHEGNGTAQELFDHYYSSYPADSPFWQVTPGGPGKEDLFHASVYN
                     RGAMTLHALRNRIGDAKMLRTVRTWFERNRGGNATVPEFIEHAERVSGQRLDGFFDEWL
                     FSEGKPRVGSATGVPRTAAARTADASAPKAVEQLNHTHELLAGMHDRG"
     gene            12098..12343
                     /locus_tag="BM394_RS09160"
                     /old_locus_tag="SAMN04487904_104165"
     CDS             12098..12343
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM394_RS09160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487904_104165"
                     /product="hypothetical protein"
                     /protein_id="WP_092976691.1"
                     /transl_table=11
                     /translation="MSNSTRGTSPSVRPIGNTALLAAGVVTAIQLSTDSPAAAGPYVVA
                     LLLCVLGTGLRIESAIRERVPETNPDTTTRQDHTSG"
     gene            complement(12377..12667)
                     /locus_tag="BM394_RS09165"
                     /old_locus_tag="SAMN04487904_104166"
     CDS             complement(12377..12667)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM394_RS09165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487904_104166"
                     /product="hypothetical protein"
                     /protein_id="WP_092976694.1"
                     /transl_table=11
                     /translation="MARLYTAEEITDQHYEPIVDQERATVGYEVYVAGDHLGSVMYNVD
                     PAGWIAYTTYTDVPIPHRRGPIAGTSIEAVLDLLQHLRDHDHIGPAMPGRE"
     gene            12815..12982
                     /locus_tag="BM394_RS22760"
     CDS             12815..12982
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM394_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_175530031.1"
                     /transl_table=11
                     /translation="MVTETRDHLIERIRRDVAAAWSAGESAVEEPLAERRTAAAVEISE
                     AAHVWPSRPG"
     gene            complement(13069..14790)
                     /gene="menD"
                     /locus_tag="BM394_RS09175"
                     /old_locus_tag="SAMN04487904_104167"
     CDS             complement(13069..14790)
                     /EC_number="2.2.1.9"
                     /GO_function="GO:0070204 -
                     2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylic-acid synthase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="menD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944029.1"
                     /locus_tag="BM394_RS09175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104167"
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="WP_092976700.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.7e-29, bitscore:
                     95.3, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPATAQAEVLVDELVRNGLRHAVLSPGSRNAALAFALHRAASRR
                     RLALHVRIDERSAGFLALGIAAASGEPVAVVCTSGTAATNLHPAVTEAGHAGVPLLVLT
                     ADRPPELRAAGANQTIDQHGLYGTSVRWFDELAVAENRPGQHAYWRGQTCRAVRAALGG
                     ARPAAPVHLNLPFREPLVPDEPAATVPTDSDGELATDRPEWCESLAGRPDGRPWTEFAE
                     APHEPARYEPESPYGLVLLAADGGEHDLDWARRLGWPVLAETGGVGHGGETLLPTGMWL
                     LELAEFLRAHRPDLVVCVGRPTVFRQVQRLLADRKVETVLLHGRSDTWPAPAHDVSLLA
                     DSVDPTAVTPDPAWLEAWSAADRKAGEELAAALDRESGPHGPVVAARVLDEIPADSTLV
                     VGSSNPARDVALSARARPDVRVHRNRGVAGIDGTVSTALGVALARETPTYALLGDLTFL
                     HDTNGLLLGPHEQRPDLTIVVCNDDGGGIFSLLEQGDPAYAQPFERVFGTPHGTDLAAL
                     CAAHGVPHRSVDHGGDLGAALRYRSGLRVVEVRTARDGQRELRERLSEAVASAVLG"
     gene            14983..16188
                     /gene="menE"
                     /locus_tag="BM394_RS09180"
                     /old_locus_tag="SAMN04487904_104168"
     CDS             14983..16188
                     /EC_number="6.2.1.26"
                     /NRPS_PKS="Domain: AMP-binding (60-307). E-value: 3e-45.
                     Score: 146.4. Matches aSDomain:
                     nrpspksdomains_BM394_RS09180_AMP-binding.1"
                     /codon_start=1
                     /gene="menE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944024.1"
                     /locus_tag="BM394_RS09180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104168"
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="WP_092977203.1"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-44, bitscore:
                     146.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSARELRPLTIPRDPGELTAVVAELRNALDGTGPALLPLAADDP
                     AAGETARALGAGEPLATVEDSESDPTSLVIATSGSTGAPKGVLLPASALRASARSTHDH
                     LGGPGQWLLAMPTHHIAGIQVLVRSIVAGHTPRAVDTREGFTAEAFADAAEPLLSTENQ
                     HYTALVPTQLGRLLDAASDPRGLRALRTFDAVLLGGAAAAPGLLERARAAGVNVVTTYG
                     MSETAGGCVYDGTPLPGVRVHVESPEPGRISLSGPTLARGYRRSPDNHGSDRAAFETGW
                     FRTGDVGQWRDGHLEVLGRADDMIVTGAVKVVPAVVERALTEHPGVREACVLGGPDPEW
                     GQAVLAAVVPERTVPDERELRRRVRQRLGAAAAPKRFVVLDELPLRGPGKPDKRALLEL
                     FG"
     aSDomain        15163..15903
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM394_RS09180_AMP-binding.1"
                     /evalue="3.00E-45"
                     /label="BM394_RS09180_AMP-binding.1"
                     /locus_tag="BM394_RS09180"
                     /protein_end="307"
                     /protein_start="60"
                     /score="146.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ATVEDSESDPTSLVIATSGSTGAPKGVLLPASALRASARSTHDHL
                     GGPGQWLLAMPTHHIAGIQVLVRSIVAGHTPRAVDTREGFTAEAFADAAEPLLSTENQH
                     YTALVPTQLGRLLDAASDPRGLRALRTFDAVLLGGAAAAPGLLERARAAGVNVVTTYGM
                     SETAGGCVYDGTPLPGVRVHVESPEPGRISLSGPTLARGYRRSPDNHGSDRAAFETGWF
                     RTGDVGQWRDGHLEVLGRADDMIVT"
     CDS_motif       15199..15249
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM394_RS09180_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="BM394_RS09180"
                     /protein_end="89"
                     /protein_start="72"
                     /score="19.8"
                     /tool="antismash"
                     /translation="LVIATSGSTGAPKGVLL"
     CDS_motif       15727..15786
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM394_RS09180_0002"
                     /evalue="2.60E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="BM394_RS09180"
                     /protein_end="268"
                     /protein_start="248"
                     /score="13.5"
                     /tool="antismash"
                     /translation="PGRISLSGPTLARGYRRSPD"
     gene            16312..17184
                     /locus_tag="BM394_RS09185"
                     /old_locus_tag="SAMN04487904_104169"
     CDS             16312..17184
                     /EC_number="2.5.1.74"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0046428 - 1,4-dihydroxy-2-naphthoate
                     octaprenyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010312430.1"
                     /locus_tag="BM394_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104169"
                     /product="1,4-dihydroxy-2-naphthoate polyprenyltransferase"
                     /protein_id="WP_092976703.1"
                     /sec_met_domain="ubiA (E-value: 1.5e-17, bitscore: 58.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASVAEWVEGVRVRTWPNAVAPVIAGSATAAGAAGFDLPLALLSL
                     VVALSLITGVNFANDYSDGIRGTDEVRTGPRRLVGSGSARPGSVLGVALGCFGIAAVAG
                     LAVLYLSGHWWLLSLGAVSIAGAWFYTGGKRPYGYAGWGELAVFCFFGPAAVLGTMYVQ
                     ADSINGSGIGAAVAMGAFSSAVLVANNLRDIPTDRQSGKRTLAVLLGDRDTRTLYVTLV
                     LAPFLITTLTGLRITPALLGFLALALVISPIRRVTRGDTGLSLLPVLRDTGLAMLLWAV
                     ATAVGLTLG"
     gene            complement(17233..17709)
                     /locus_tag="BM394_RS09190"
                     /old_locus_tag="SAMN04487904_104170"
     CDS             complement(17233..17709)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM394_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487904_104170"
                     /product="hypothetical protein"
                     /protein_id="WP_092976705.1"
                     /transl_table=11
                     /translation="MLRKAALYLAIGWVVLVVAGFGVLYGAATLNATTVYSDRGVTEEN
                     ADEYRWSGKTIALTDNLRKNGWASCEVVPDSGERRNIRSPRNDSTVSYRQYQPWFSGAA
                     TVTCGEQVTIRSGATLTMYKLATSRLVQFGSAAIAAIPLVLALIWHYGLVRVRR"
     misc_feature    complement(17704..17706)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17720..18154)
                     /locus_tag="BM394_RS09195"
                     /old_locus_tag="SAMN04487904_104171"
     CDS             complement(17720..18154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019852701.1"
                     /locus_tag="BM394_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104171"
                     /product="hypothetical protein"
                     /protein_id="WP_092976708.1"
                     /transl_table=11
                     /translation="MRDWKTQEIRDAEAALDEAVTDAERVAARAEEMNDELPEAELSEE
                     QTEQIEQLVRRGEAPAGIAELQRRIDEGELSWQQVTSGRAVADEGVRRAFEEGVPAMRQ
                     VKEMLDEGHEATEIIANDPNRAPEQDDEEPPDSFLRSGNW"
     gene            complement(18204..19187)
                     /locus_tag="BM394_RS09200"
                     /old_locus_tag="SAMN04487904_104172"
     CDS             complement(18204..19187)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019852700.1"
                     /locus_tag="BM394_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104172"
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_092976711.1"
                     /transl_table=11
                     /translation="MAFADVDDPIAKLEQRTGQADSETLKSAIQDASWQVQGVNWIYEQ
                     VAGQNLVESLISPITGDFAKIEQNAKAWNDIGESLRAVRRNLNHGVSDLRQSWDGAAAA
                     AFESMMVGGWTVALEADAAAADLVSTAFTKAADTSKMLCSKILELIDKLVNRLIQAACT
                     AWVPVGGWANAVRIVIQCIDIVFMIMDMIQAIIRIYQGVKQVIEGVKSTGTSLARIQEV
                     ASGDGPRGTGDAVNVALDRTRELTGAVSGVTDGVNQVREGATQVRGGASDVRQTTSDMG
                     GNGNTTVRQGDAEQRGGARQQGGTESPERSGEQHGSGRRTSMAGNL"
     gene            complement(19324..19653)
                     /locus_tag="BM394_RS09205"
                     /old_locus_tag="SAMN04487904_104173"
     CDS             complement(19324..19653)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944015.1"
                     /locus_tag="BM394_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_104173"
                     /product="hypothetical protein"
                     /protein_id="WP_092976714.1"
                     /transl_table=11
                     /translation="MSERVEAVPSRLRDYGGLLRRNAESFNGIESYANETASDTSGFTG
                     VMASLIPVVQGATALYSETLRLAHAKLLRVREELDNTAAEYEEREREIEQLLSGIETAL
                     SGMRP"
     misc_feature    19752..19763
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.59"
                     /tool="antismash"
ORIGIN
        1 gggtagtcct tgcgctgcgg gtggccgtcc cagtcgtccg gcatgaggat ccgcgtcagg
       61 gccgggtggt cgtcgtagac gatgccgtac atgtcccagg cctcccgctc ctggaagtcg
      121 gccgtcggat agacgtcgac caccgaggga acgtgcgggt cggccacgtc cacggcgacc
      181 tcgacgcgga tccgacgccg gtaggtcagc gaggtgaggt gacagaccga gtgcagccgc
      241 tgcggcacgt cgggaccgta gtccaccccg gacagactgc tgcagagctc gaaccgcagc
      301 gcgggctcgt cgcggaacgt ccggcagatc tcgaccagat gctcccggtc gacgtagaag
      361 gtgatctcgc cgcggtccac ggtgatccgc agtaccgccg agtccgggat accgcgccgc
      421 ttcatgccct cgaacagctc gtcggccacc tcgtcgaacc agcccccgta gggccgttcc
      481 gcctccggtg gcacgtaggc cggcacccgg agaccgccgt agcccgaggt gtccccgctg
      541 ccggtcacac cgaacatgcc cttccgggcg cggcccgcca ccatccgctc ggcggccact
      601 tcctccgtgg gaccggtgtg ctcggccgcc gtctccggga gtcccccgct ggattcgtca
      661 ccgctcatcg ccgaatcacc tgcccgccgt cgtctcgttc ggttccgcgc ggccgcggga
      721 gtcaccgggt ggcaaactct cgatcccggc ggcgcccagc tcgccctccg cgcccatctc
      781 gcggcgctgc gcgtcctgct gccgctcggc catgcgccgc ttggagccgc tgcggggtgc
      841 gtacttctcg gaggaggcgg gcagttccgt gcggtgcccc tgctccacct gctcggccgc
      901 gcgcttgccg ttgatgggct cgtccatgac cttggcgtgc agcttgagga tcgcgtcgag
      961 cagcatctcc gggcgcggcg gacagccggg cagatacatg tccaccggaa ccacgtggtc
     1021 cacgccctgc acgaccgcgt agttgttgaa catcccgccg ctggaggcgc agacccccat
     1081 cgcgagcacc cagcggggct cgggcatctg gtcgtagatc tgccgcagca ccggggccat
     1141 cttgttggtg acccgaccgg cgacgatcat cagatcggcc tgccggggcg tggccgagaa
     1201 ccgctccatc ccgaaccggg cgatgtcgta gcgggaacca cccacggtca tcatctcgat
     1261 ggcgcagcag gccagcccga acgtggcggg ccacatcgag gtcttacggg tccagttgac
     1321 gagtttttcc acattggcca gcaggatgcc gttgggcagg ctttcctcaa gccccatctc
     1381 ggcactcctt cccacgagtc gccccggcga acggggcacc accgatcccg acgcgcccgc
     1441 accgggcggc tgtcgtactc acttcgccgg tcagttccaa tcgaaaccac cacgccgcca
     1501 cacgtagaga tcggcgaaac cgaaggtcag gatgaacaga atcaccgcga ccacgccgta
     1561 gagcccgaga gcgtccgcgg aaacggcgta ggggaacaga aagaccatct cgatgtcgaa
     1621 gaggatgaac atcatggccg tcaggtagta ggcgaccggc atccggccac cgccaccgac
     1681 cggctgcggc gagggttcga tcccgcactc gtaggcgtcg agcttggcct tgttgtaccg
     1741 acgcggaccg accagcggcg cgatcgcgac ggagaacgcg gcgaagccga acgccaacgc
     1801 gaacatcagc accagcggga tgtagggatc cagcactgtg cctgcctcct taatccagtt
     1861 cccgctacgc cccgagcgaa ctcggcgacc acactcagca ctttatgcgc ccggttgtac
     1921 gcacctcgta ttgaggtgaa cctaacttta tgaattacgg cacaaagtcg ccgaaatctg
     1981 atcagacggg cgccctcagg cgctaggtgt gagccgagta gtggtactta tcacacggtc
     2041 cacggcgtca cctcccctgc tgtcgtagag gttggccagc agcttgagca cgaagcgcat
     2101 cagcgactcg cgggggagtc cgtacttggt ggcggtgcgc atcaccgtcg gatgaccgat
     2161 gatcttgctg aacaggtttc ccatccggaa gtagccgccc agcgactcgg cgacggcacc
     2221 ggggtagcgg gccagcgcgc gctccctggc cgcggcgtcc gtacgagacc tcgcctggat
     2281 cacgcactcg gctgccaacc gggccgcctc catcgcgtag gcgatcccct cgccgttgaa
     2341 cgggttgacc attccgccgg agtcgccgac caacaacagg ccggagctgt agtgcggcat
     2401 ccggttgaac cccatcggca gcgcggcacc gccgatcctg ccggtggcgt tggcctcccg
     2461 aagtccccac tcctccgggg tgccgtccaa ccaggtgcgg agcagcgcac ggtagtcggt
     2521 cttgccgtac gccttcgagg tggacagcac acccagcccc acgttgacgg tgccgtcgcc
     2581 catgccgaag atccagccgt agccgggcaa cagctcggcg cccttcggat tcgagttgtt
     2641 ccagagctcc acgtgcgact ccaggtagtc gtcgtcggcg cgtgggctct cgtagtaacg
     2701 ccggacggcc acccccatcg ggcggtcctc cctgcgctgc aggcccatgg acagcgccag
     2761 cctgccggaa accccctcgc aggagatgac cagcggggcc cggtagctga cctcggcgcg
     2821 ctccggtccg gacttggcgt gcacgccggt gatacgaccg gttcgctcgt cggtgatggc
     2881 ctcggtcacc gaggtccgct gcaccagcct cgctcccgcc cgctgcgcgt ggcgtatcag
     2941 caggtcgtcg aagtcgttcc tgggccggac gacgccgtag ggcgggtact cggccagttc
     3001 cggccagtcc atctccagcc gcacgccgcc cccgacgacc cggagccccc ggttgtgcag
     3061 ccagcccgct tccgggcggg tgtccacccc gaggtcgatg agttccttga ccccgcgcgg
     3121 tgtgattccg tcgccgcaca ccttctcccg ggggaaggcg ctcttctcca ggacgagaac
     3181 gtccagcccc gccttggcga ggtaggtggc tgcggtggcc cccgccggtc ccgctccgac
     3241 gacgatgacc tcggcgtcgt cggtggcccg gcctcggatg ggggtggttg tcatggtgct
     3301 ccttgtccag ccttgctgtt cggatcgacg tcgttcccct ccgatgatcc cggcggaaca
     3361 cgccgccgca ccgcccgagc gacatcggcg accttgtgaa taagttcact aacgagtcta
     3421 ggacggacat cccgcgcgat cgagacatcg cgagcgaaag aaactcacgg ccgcggcgga
     3481 agcagcgcgg gaggcacgaa cgcgggcagg cacggaacac ggcatcgtcc gcccgaaaca
     3541 gtgacggtca ctgcttcctt cgggggatcc gagtacgccg ttcgggggtg tcgatttctc
     3601 gcgaaatcgc cgcgccgctg gggtggcacg gtgccgcact ccgaccaccc tcgcaggccg
     3661 aactccagcc acctacgcaa tcggcaccgc cgcgggttct cccgtgcggc tctcgcgagg
     3721 acgccggaga cgttgtgtgg tacctacccg atgtctccgg ccccgcggcg agagccgtgc
     3781 gagaggttcc gccgagtgag cagtcgaagc aacccgaccg gaagagttcg atcagtaagg
     3841 tttgcgggcg tggtgcaggg ctacgattcc tccggtgaga tcccgccagg ccacctcgga
     3901 ccagccggag cgggcgatcg tagcggcgag ctcccgctga tcgggccagg cgaggatcga
     3961 ctcggccaga tagacgtagg cgtccggatt gctggcgacg gtccgtgcga ccggcgggac
     4021 cgcgcgcaac gcgaggttgc gataggcagc gcgcaacggc ctgttggtgg gggtggagaa
     4081 ctcgcagatc accagcctgc caccgggacg gaccacgcgg gccatctccc gcagcccggc
     4141 ctcggtgtcg gccaggttcc gcagtccgaa caacatggcg actccgtcga aagcaccatc
     4201 ggcgaacggg agccgcagcg cgtcggcggc caccatcgac agctcccggt gctccccggc
     4261 cgcgagcatc cccagtgaga agtcggcggc cacgcagtac gcaccactcc gggagaactc
     4321 ggcggtggag acgccggtgc cggcggccag atccaggatc cgctcctcgg gagccggagc
     4381 gagcgcccga cgggtggcgt cccgccagtg gcggtcgagc ccgaaggaga gcaccgtgtt
     4441 ggtgcggtcg tagccacggg cgacgccgtc gaacatcgcc gctaccgcac ggggattcct
     4501 gtccaggccg gctcgagaca cacccgcact ttactagtag gagtcggcga cccggtttcc
     4561 gcaggtgtcc actcggcgga acctctcgca cggcggtgcc gagtgcgtgc atggctggga
     4621 ttcggcacgc gtacgtggtc ggagttcggc tctgcgtaac aacggcccgg cgatttcgtg
     4681 ggaaatcgac ggtaaccggg ccgcgtggtg gtgaccgcta tccgacccgg tgccgccgca
     4741 ccgtgggacc ggcgatttcg tgggaaatcg acgccgttgc ccccgaaagc ggtaccgcgt
     4801 cccgggttga gcgattagaa tccctctcgg ccgatcgggc gtggcacgca ctgcgtgtgg
     4861 gccagtcggc ccggaccacc cgcaccgctc cgtacgccac ccgggattct tgaccggagc
     4921 atcgccgcgc gtccacacgc aattggtctg ccggttaccc atagcgacca caatggtgcg
     4981 gtatgagtgt ttcgcctccc ccgaagaccg gccgtgcgga acaggccctg atctcacgcg
     5041 ccttggagac cgcggggcgg ctggccaacg aagcggccga tgtcatcacg gcaacggcgg
     5101 gacacgacac accaccgtcg gagccggact cccccttcga ctgggtcacc gatgtgggac
     5161 gcaccctgga acgccacacc cggagaatcc tggcggagca ctttccggga ataccggtgt
     5221 acggcgagga gttcgacgcg gccgcgttgg gcgggggaca gggcggtttc cgctgggtgg
     5281 tcgacccggt ggacggcacc gcgaactacg tcgccggagt gccctggtgt gcctacagtc
     5341 tggcgatgct cgacgcacag gggcccgtgg tcggtgtggt ggccgatccc taccgggcgc
     5401 agatatacgc ggccgctcgc gaccggggga tgcgggcgaa cggaaaaccg gtgcggttga
     5461 cggaagcgcg ttcccccagg gcgagcatcg tctgcaccga gttcaccagg tacggcccct
     5521 ggcggggtat ggacaggttc ataaccaacg ccgctgccga tcacgtgggg gttcgggttc
     5581 tcggctcacc cgcgctggcg atcacgcagg tggcgctcgg gcaggcggtg gccgccgtgc
     5641 ttccctccta cggggagtgg gatgtggcgg gagcgctggc cctcgccgtg gagtccgggg
     5701 ccaacgtgct ggacagctac ggaaggcccg cctcgctgcc gcacgacggt cttctggtgg
     5761 ccgctcccgg gatcaccgag accgcgttcg gctggtggtg gcacgcatcg ggagcgggct
     5821 gatcaacagt ccaccgttca gacccgcgcc ctcaccagcg agggcgtctc gggcgttccg
     5881 cccgaaccgg cccttccctc caggatcgcc gacatcgcgg gcagcagggg gaatcgctcc
     5941 cgcaacgcgg cgattcgccg ctgtgcgtgc tcctggtcgg cccccgcggc cagctcggcg
     6001 accacacctg ccaactggtc tcccagttcg gtgaaccgcg ataccgccat cacgacaccg
     6061 ccctggatcc tgcggagcgc gacgcgccgt gtcgaatcgg cggtggcgac cgtggagtca
     6121 ccggcgtcga gctcacgggc gagctgcacc agcgttcgta ccgtgggcag ctcggcgtcc
     6181 atgcggtaaa cgacctgccg caacccgcga cgcaccggta gcgaggagac cgtgtcggcg
     6241 gctcgaaccg cccggtgcac ggcctgctcg caccggttga gttcgcacag ccacgcgtcg
     6301 cggtgctcgg tcagcgcgtg ttcgagcccg ccacgggcgt cggtgctggt gcccgacgtg
     6361 gtcttcggcg gctcttcggg gaccggaggc gcgctcgacg aacgtcgagc caacaccccc
     6421 aggagcacac cgagcacgcc ggcggccaac gccacgatca ggtgcgtcca gaatccgccc
     6481 atttcccgcg gtgcccttcg ctcgaactcc ccctggccgt gtaccggggt tcctcctgat
     6541 cggaacggat ggaacgctcc gctccacgag gactcccgag gcgcgcacta cgccactcga
     6601 agagtgtgcc cggagaacgg tccggttcgc ttgggggaaa gtactcaaat atcgaccggt
     6661 ggagtcccca ccggttctcg gattcccgac gggctctcgg gttccgaacg gccgctcagg
     6721 cctcgaccgt ctcgtactgc cgcatctcgg cgagcaggaa ctccagcgcg gtggtgtgca
     6781 caccggtgcg tcccagcggc tccacgtcgt cgtggaagac ccgcgcgtcg ggcggttcca
     6841 gtcgcgccac cgagagcact tcgtcgagca acgccgccac ttcggtgcgc agcccggccg
     6901 gatccaccgc gaagccgagg tcggccagcc tgcgctccac ggggtgtggg acgaacagtt
     6961 cgccggtcat cggccagacc cgagccagcc cggtgctcat ccgctcccgc gaggcggacg
     7021 tgccgtcgcc gaggcggata acccactgcg cggcgtgatc gcgatgtccg cgcacttccg
     7081 gcagcgccac ccgcgccagt tccgagagca ccggatcacg gctggcgacg agcttgccga
     7141 acagggctgt tcgccaggcc gcgcagacca tcagcctggc gatggagacg gcgaagtccc
     7201 cacccgctcc ggggccgcag tcgagctcga cgagccggac gttgcggaac tcctccacgc
     7261 ctcgttcgtg cgcgagcagg ttctcgtcgc gcccgctgtc ctccacggtc gcggcgcggt
     7321 gcaacagctc cctggcgtgg ccgagcgact ccagcaacat gccgacctga acacagtcct
     7381 cctccaggtc gggagagtgc tggcaccaac cgacctgacg tcgtgccagc acgagagcgt
     7441 cgtcgccgag catcatgcag tagaccgaga ggtcggcagc ggaaacatcg tccggaaccc
     7501 cgcgatccgt cgacgtcagt ggggtgcccg cggcccgcac ggtccaacgc tgctgttcac
     7561 cgaggggatt ggaaatgctt tcgggcgtgg cggtgccccc gccttcacga gctccccgcc
     7621 gttcggggaa ccacctcggt gcgtcgccga ttccggaagt aaccatggcc gcccccgttc
     7681 cgccccggtc cgctcggctc cggtccactc agcccgaacc gcgggatgcc acttcggccg
     7741 tcagcactgg ttgggctgtc agcgccgggt cacaccgcca ttctcccacc gcaacgcgat
     7801 acccccaata gagtgaagaa cagtggggcg cctcaagcgc ggacagtgcg ccgcgtcagc
     7861 cagtaagcgg gcagcacgat cgcccacagc accgccagcg cgctgccgac gggcagcagc
     7921 gccaccgaca tgttcctgcc cgccacgcgc accagatccg ggttccccct gtcgaactcg
     7981 acgctgacca gctgcccctc ctgcaacccc acgggataga gcacgccgtt cggcggggtg
     8041 tacacccggc cactgtcggt gttgaaccgg accacggtac gcaggtagga cttctccacg
     8101 acctcggccg aggcggttcc catgtcctgt tcgatgctgc ggtcgtcgat gtggcaggcc
     8161 agcaacaacg ccaacccgag ggcggtgaag aaaccaccca ccgccagcac cagcgacggc
     8221 gcgaggcgcc ggaacccgcg tggaaaccac cgcgttcccg aacggttgtc ggcgctgttc
     8281 ggttccgcgg tgccgaccgt ccgctccgat tgcgtctcgc cagtcacgac cagtgattgt
     8341 agtgcgcccg gcgaaccgga tcacgagacg acccgttcga aaacccgggg cgaggcccgc
     8401 cctccccggt ccgaggactt tccccgcgga gctcccgctc gctcgtgcgg gtattcgaag
     8461 acactgttcc gagcaggtca ccggctcgcg cgaccaggcg gttccgtgac gcgctccgcg
     8521 cgtcaggacc gacgtcacgt gcgcgccacc ccgtttcgcg tcgcgatgta cggcgcgcgt
     8581 ttcccgtgac ggccgacacc tccgaggtgg cggcgggcac gcgcgaggcg ggtgtcaccc
     8641 gacagagtcg caggacacct accctcgaaa cgtggaccac ttccagcaga atctgactgt
     8701 ccgcacacgt agggttccgt ctccagaggg acactacgat cttttggacc tgttgcccga
     8761 agggatatca cccgattcgg ggccgctttg ctggacgcga cacggtgaag gggtggtcgg
     8821 ctggggagaa gcgctgcgca tcgagacgga gcgcgaggag cggttcgtgg cggcggacga
     8881 gcggtggcaa cggctcgcgg cgcggatgga ggtcgacgac gaggtgaggc tgccggggac
     8941 gggtccggtg gccttcgcca gcatcgcctt cggcgacgat cccggttcgt cggtgctgat
     9001 agtccccgaa gtcgtgctcg ggcagcgcgg cggggtgcgt tggatcacca ccatcggtga
     9061 gcacgaccgg cggctttccc gtgccgctcc cgcacgggct cccggcacca tccgctacag
     9121 cgacggggag ttccccacca cgcgttaccg gcaggcggtg gccgaggcgg tacgccgaat
     9181 gcgcggctcg accgaactga gcaaggtggt gctggcgcac gatctgctgg ccaccacctc
     9241 ggaaccgctg aactcgcgct acctgctcgg caacctcggc aggcgctacc ccgggtgctg
     9301 gacgttcgcg gtggacgggc tggtgggagc cacgccggaa ttactgctgc agcgcaacgg
     9361 caacgaggtg agttcccggg tgctcgccgg gacggcttgg ccgcacgagg ggcgcaccca
     9421 gcggcagctg atgtcggagc tgctgggctc ggcgaagaac cgtggggagc acacttacgc
     9481 ggtgcgttca ctggcggacg ggctggagcc gttctgcaag gagctggacg tgcccaccac
     9541 ccccgaggtg ctgcgactgc gcaacgtgat gcacctggct tcggacgtct ccggacaact
     9601 ggacccgatg ctcgcgcaga acggccacgc cgggctgctg cgactggtgc agtcggtgca
     9661 tcccacggcc gcggtcggcg gaaccccgac ggcgggcgcg atcgaactga tcgacgagct
     9721 ggaggagatg aaccgggagc gctacgcggg accggtcggc tgggtggacg ccgacggcaa
     9781 cggggagttc ggtatcgcac tgcgctgtgc acggatcacg tggcactccg gcgaggggtc
     9841 gcgggcgcgg ttgttcgcgg gctgcggcgt ggttcccgac tccgatccgg acaccgaggt
     9901 caccgaggcg gaggcgaaac ttctccccgt ccgggaggct ctggaagggg tgcgttgaac
     9961 gcggatgctc gtgggcgccg aagtccctcc cggggagttc tcactcgtga tcggcgaggc
    10021 acgcggcgcg tagtttccgc agcaccgcgt tcacgtcgtc ggcggccgca ccgggatccg
    10081 cccggtaggc gatgatcagc ttctcggtca cacgctcggg atcctcaccg ttgagcagat
    10141 cgcgcaacac cctggctccg gtcgtgttga gctgtccgga ctcctcgtcg tgcaacaaca
    10201 tccttctcgg acctccacga gcccgcccga ccgaagacac ggctccgcga atccacagcg
    10261 gaccgatccg gtcctttcac tcgaaggcta gcggggtctc cgggcaccgc aaagccgccg
    10321 caccggaatt cacgcgaagg tacgactcgc ctcgatgtcg aggggccgcg aagaaccgtc
    10381 cccgcccgcg cggtgcgagc ggggacggtg gcggaacccg cgggttcagc cgcggtcgtg
    10441 catcccggcc agcaactcgt gagtgtggtt cagctgctcg accgccttcg gcgcggacgc
    10501 gtccgcggtc cgcgcggcgg cggtccgggg aaccccggtc gcactgccca cccgaggttt
    10561 gccctcgctg aacaaccact cgtcgaagaa gccgtccagc cgctgtccgg aaacgcgctc
    10621 ggcgtgctcg atgaactccg gcacggtggc gttgccgccc cggttccgct cgaaccaggt
    10681 tcgcacggtg cgcagcatct tcgcgtcgcc gatccggttc cgcagggcgt gcagcgtcat
    10741 ggccccgcgg ttgtagaccg aggcgtggaa gaggtcctcc ttgccggggc caccaggcgt
    10801 gacctgccag aacggcgagt cggccgggta cgacgagtag tagtggtcga acagctcctg
    10861 ggccgttccg ttcccctcgt gctcggccca cagccattcg gcgtaactcg cgaaaccctc
    10921 gttgagccag atgctcgacc agtcgtccag cgccaccgag tcgccgaacc actggtgcgc
    10981 gagctcgtgg gtgaccaccg aggtgttgga accgatccgg aagaagttcg ggctgtagac
    11041 gggcctggtc tggttctcca gggcgaaccc gagcccttcg gcgggcacca caccgccctg
    11101 ggtctcgaac gggtacggtc cgacgatttc cgagaggaat tccaggatct cgggagtgcg
    11161 ttccagactg gcctcggcgg gccccttgat gtcaccgagc ccgtcggcgt aagcggtgat
    11221 catcggctgg tcgaaggcac ccttcttgct gtgcacgtcg tactgcccga tggccaggaa
    11281 cgcgaggtag gtcgcactgg ggctgggcat gcgccagttc cagcgggtcc agtcgccctg
    11341 gcggatacga gcggtcatcc tgccgttgga gagcacttcg gttccgttcg gcacggccac
    11401 cgagatgtcg aaggacgcct tgtccgaggg gtggtcgctg gcggggaacc accactcgga
    11461 gatcaggggt tgtccgaccg cgacggcacc gttctcggtg cgcttccagg gggtctgccc
    11521 gtcgacctcc actgtggatg gtttgtcggc atagctgacc acgaacgtgg ccaggctccc
    11581 ctccggcagt gctcgcttcg gtgtgaccgt cacctcggtg gcgccctgcc gctcgacccg
    11641 cgcgggcgct ccgttgaccc gcacggaccg aatctccagc gcgaagtcca ggttgaacga
    11701 gctcaggtcc tcggtcggtt cggccacgat ggtcgtggtg ccgcgcagca ggtcgttctc
    11761 cggctggtag cgcagccgga tgtcgtagtg ggacacgtcg tagccgccgt tgcccgcctc
    11821 cgggtagtac gaatcgccga cgccgggtgc gcccgcgccg ccggttcccg ccagggccgg
    11881 ggccgcgaga accaccgtcg cggcgcaggt ggcgacagcg gtacgtagcg ctcgtctccg
    11941 caacaagtga caactcctaa cacggtgctc gatccggaac acaaccagtg atcatacgca
    12001 cacgaaacgg gatcggagcg gatcagcggg caccggtcga acatcgaacc gtgggcggcc
    12061 ctgtcggccc ccggaggctc ggacacacaa tgcgggcatg tcgaacagca cacggggaac
    12121 ctccccgagc gtccgtccga tcgggaacac cgccctgctc gcggccggag tcgtcaccgc
    12181 gatacagctg tcgacggaca gtcccgccgc ggcaggccct tacgtcgtgg ccctgctgct
    12241 ctgcgtgctg ggaacgggac tgcggatcga gtcggcgata cgggaacgcg tgccggaaac
    12301 gaatccggat acgacaacac gccaggacca cacgagtggg tgacgttctt cgtggcaccg
    12361 ggtgcgcgag aaaccgtcac tccctgccgg gcatggccgg tccgatgtgg tcgtgatcgc
    12421 gcaggtgctg cagcaggtcg agcacggcct cgatgctggt ccccgcgatc gggccgcgcc
    12481 ggtgcgggat cggcacgtcg gtgtaggtgg tgtaggcgat ccacccggca ggatcgacgt
    12541 tgtacatgac gctgccgagg tggtccccgg cgacgtagac ctcgtaaccg acggtcgccc
    12601 gctcctggtc gacgatcggt tcgtagtgct ggtcggtgat ctcctcggcg gtgtacaacc
    12661 gggccatcgc tgctcccgtg gtcggattcc ggcgtaacgg caccgcgcgc gttggtggca
    12721 cggcagcccc gtgatccgac agtctcgcac cgacaccgat ccgacacgag gggtgttcac
    12781 ccgaccgtcc ggcgaattcg ataaaaccgg acgcgtggtc accgaaaccc gcgatcatct
    12841 gatcgaacga atccggcggg acgtggcagc ggcctggagc gccggagaat ccgccgtaga
    12901 agaaccgctg gccgaacgcc gtacagccgc cgctgtcgag atctcggagg cagcgcatgt
    12961 ctggccgtcg cgacccggtt gaacgtcccg gccgtcaccg ctgatcgggt ttggaaggat
    13021 ccggatatcg gcgtggaggt ccgactgatt cgctgatttc ggctccgctc agccgagcac
    13081 ggcggacgcg acggcttccg acagccgttc ccgcagttcg cgctgcccgt cacgcgcggt
    13141 gcggacctcg accacccgca acccggaccg gtagcgcagc gccgcaccga ggtccccgcc
    13201 gtggtccacc gatcggtgcg gcaccccgtg cgccgcgcac agcgccgcca gatcggtgcc
    13261 gtgcggggtg ccgaagaccc gctcgaacgg ctgggcgtag gcagggtccc cctgctctag
    13321 cagcgagaag atcccgccgc cgtcgtcgtt gcacaccacg atcgtcaggt ccgggcgctg
    13381 ttcgtgcggc cccagcagca agccgttggt gtcgtgcagg aatgtgagat cacccagcag
    13441 cgcgtaggtg ggtgtctcgc gggccagggc cacgccgagc gccgtggaga ccgtgccgtc
    13501 gatgcccgcc acgccccggt tgcggtgcac ccgcacgtcg gggcgcgctc tggcggacag
    13561 cgccacgtca cgtgcggggt tcgaggatcc cacgaccagc gtggagtcgg ccggaatctc
    13621 gtcgagcact cgggcggcga cgacggggcc gtgcggaccg gactcgcggt cgagtgcggc
    13681 tgccagctcc tcccccgcct tccggtcggc cgccgaccac gcttccagcc acgccgggtc
    13741 gggagtcacc gccgtggggt ccaccgagtc ggccagcagc gagacgtcgt gcgcgggcgc
    13801 gggccaggtg tccgaccgcc cgtgcagcag gaccgtctcc accttgcggt cggccagcag
    13861 ccgctgcacc tgccggaaca ccgtcggcct gccgacgcag acgaccaggt cggggcggtg
    13921 ggcgcggagg aactcggcga gttccagcag ccacatcccg gtgggcagca gcgtctcccc
    13981 accgtggccc acacctccgg tctcggcgag aaccggccag ccgagtcgtc tcgcccagtc
    14041 gagatcgtgc tccccgccgt ccgcggcgag cagcaccagc ccgtacggcg attcgggctc
    14101 gtaccgggcg ggttcgtgcg gtgcctcggc gaactcggtc caggggcgcc cgtcggggcg
    14161 tcccgccagg gattcgcacc actccggtcg gtcggtggcg agctcgccgt ccgagtcggt
    14221 cgggacggtc gcggccggtt cgtcgggcac gagtggttcc cggaacggca ggttgaggtg
    14281 caccggcgcg gccgggcgag caccgccgag ggccgcccgc accgcccggc aggtctggcc
    14341 gcgccagtag gcgtgctgcc cggggcggtt ctcggcgacc gccagttcgt cgaaccaccg
    14401 caccgaggtg ccgtagagcc cgtgctggtc gatggtctgg ttggccccgg ccgcgcggag
    14461 ttcggggggc cggtcggcgg tgagcacgag cagcggcacc cccgcgtgcc ccgcctcggt
    14521 gacggctggg tgcaggttcg tcgcggcggt gccggaggtg cagaccacgg ccaccggttc
    14581 cccgctcgcg gcggcgatgc cgagggccag gaaccccgca ctgcgctcgt cgatccgcac
    14641 gtgcagcgcg agacgtcgcc gggacgcggc gcggtgcagc gcgaaggcca gcgcggcgtt
    14701 tcgcgacccc ggggacagca cggcgtgccg cagcccgttg cgcaccagct cgtcgacgag
    14761 cacctcggcc tgggccgtgg cgggattcaa aggatcaccc cggtgtccgg gagagctgcg
    14821 gtggactgct cgtcactcta cagaaccttc tcacctccgc tttcgcaggt tctgccgatc
    14881 gggaacccgg gcggcggagc acggcggacc tcggtgcggc cggcacggag acgggagcgg
    14941 ggacggcgga accacggccg ggccgggcgg acaatggagg ccatgagcag cgccagagaa
    15001 ctccgccccc tgacgattcc ccgtgatccg ggcgagctga cggcggtggt agcggagctg
    15061 cggaacgcgc tggacgggac cggcccggcg ttgctgccgc tggcggcgga cgaccccgcc
    15121 gccggggaaa cggcccgtgc gctcggcgcc ggggagccgc tggccactgt cgaggactcc
    15181 gagtcggatc ccacgagcct ggtgatcgcg acctccggct cgaccggcgc gcccaagggg
    15241 gtgctgctgc ccgcctccgc gcttcgtgcc tccgcccggt ccacccacga ccacctcggc
    15301 ggccccggtc agtggctgct ggcgatgccc acccaccaca tcgcgggaat ccaggtgctg
    15361 gtccgctcga tcgtggctgg tcacaccccg cgagccgtgg acacgcggga gggcttcacc
    15421 gccgaggcgt tcgccgacgc ggccgagccg ctgctgagca ccgaaaacca gcactacacg
    15481 gcgctggtgc ccacccagtt ggggcggctg ctcgacgcgg cgagcgatcc gcgcgggctc
    15541 cgggcgctgc gtaccttcga cgcggtgctg ctcggcggcg cggcggcggc accgggcctg
    15601 ctggagcggg cgcgcgcggc gggggtgaac gtggtcacca cctacggcat gagcgagacg
    15661 gcgggcggct gcgtctacga cggcaccccg ctgcccggtg tcagggttca cgtcgagtcc
    15721 ccggagccgg ggcggatcag cctgtccggc ccgacactgg cgcgtggtta tcgccgctcc
    15781 cccgacaacc acggctccga tcgggcggcg ttcgagacgg ggtggttccg caccggtgac
    15841 gtcggacagt ggcgcgacgg gcacctcgaa gtgctgggcc gggcggacga catgatcgtc
    15901 accggcgccg tcaaggtggt gcccgcggtg gtggaacgcg cgctgaccga gcaccccggc
    15961 gtccgcgagg cgtgcgtgct cggcggtccc gacccggaat gggggcaggc cgtgctggcg
    16021 gccgtggtcc ccgagcgcac cgtgccggac gagcgggagc tgcgcaggcg cgtccggcag
    16081 cgtctcggcg cggcggcggc cccgaaacgg ttcgtggtgc tcgacgagct gccgctgcgc
    16141 gggccgggca aacccgacaa gcgggcgctg ctggagctgt tcggctgacc gctccgcccc
    16201 tcgtgcgctc ctcgtacgca ccgcgtcgcg caccgtcacc gctcggtgac cgagatcagg
    16261 cgcgacaccc tggggcgata tcacggatca ccggtgcgcg aggattgccg catggcctca
    16321 gtcgctgaat gggttgaagg tgttcgggtc cggacctggc cgaacgccgt ggctcccgtg
    16381 atcgcgggta gcgccaccgc cgccggagca gccggattcg acctcccgtt ggcgttgttg
    16441 tcgctggtgg tggcgctctc cctgatcacg ggggtcaact tcgccaacga ctactcggac
    16501 ggcatccgcg gcaccgacga ggtgcggacc gggccgcgac ggctcgtggg atccggctcg
    16561 gcacgtccgg gcagtgtgct gggagtggcg ctgggctgct tcggcatcgc cgcggtcgcc
    16621 gggctggccg tgctctacct gagtggtcac tggtggctgc tgtcgctggg agcggtcagc
    16681 atcgcgggag cctggttcta caccggcggc aagcgaccct acggctacgc cggctggggc
    16741 gagctggcgg tgttctgctt cttcggcccg gccgccgtgc tcggcacgat gtacgtgcag
    16801 gccgacagca tcaacggttc ggggatcggc gcggccgtgg cgatgggggc gttctccagc
    16861 gcggtgctgg tggccaacaa cctgcgggac atccccaccg accggcagag cggcaagcgc
    16921 acgctggcgg tgctgctcgg cgaccgggac acccggacgc tgtacgtgac cctggtgctg
    16981 gcgccgttcc tgatcaccac gctgaccggg ctgcggatca cgcccgccct gctcggcttc
    17041 ctcgcgctgg cgttggtgat atcgccgata cggcgggtga cgcgcggcga caccgggctg
    17101 agcctgcttc cggtgctgcg cgacaccggg ttggcgatgc tgctgtgggc ggtggcgacc
    17161 gcggtggggc tgactctcgg ttgagagccc cggatgccgg accgggcacc ccggtccggc
    17221 accgagaacg cgtcaccgcc gaacgcgcac cagcccgtag tgccagatca gcgcgagcac
    17281 cagcgggatc gcggcgatcg cggcggagcc gaactgcacc agccgcgagg tcgccagctt
    17341 gtacatcgtc agtgtggccc ccgacctgat ggtcacctgc tcaccgcagg tcaccgtggc
    17401 ggcgccggag aaccacggct ggtactgccg gtaggagacg gtggagtcgt tgcgcggact
    17461 ccggatgttg cgtcgttcgc cgctgtcggg aacgacctcg caactggccc atccgttctt
    17521 cctgaggttg tcggtgagcg cgatggtctt cccgctccag cggtactcgt ccgcgttctc
    17581 ctcggtgacc ccgcgatcgg agtacaccgt ggtggcgttc agcgtcgcgg ccccgtagag
    17641 caccccgaac ccggcgacca cgagtacgac ccagccgatc gccaggtaca gcgctgcttt
    17701 ccgtaacatc cgtcctcact caccagttac cgctccgcag gaacgaatca ggcggttcct
    17761 cgtcgtcctg ttccggggcc cggttcggat cgttggcgat gatctcggtg gcctcgtgcc
    17821 cctcgtccag catctccttg acctgccgca tggcgggcac accctcctcg aaggcgcgcc
    17881 gcaccccctc gtccgccacc gcccggccgc tggtcacttg ctgccagctc aactccccct
    17941 cgtcgatgcg ccgctgcaac tcggcgatcc cggcaggagc ctcaccccgc cggacgagct
    18001 gttcgatctg ttcggtctgc tcctcggaga gctccgcttc cggtagttcg tcgttcatct
    18061 cctcggcacg cgccgcgacg cgctccgcgt cagtcacggc ctcgtcgagt gcggcctccg
    18121 cgtcgcggat ctcctgtgtt ttccagtccc gcaagtcctc acctcgggtt cgccggtttc
    18181 gacgggttcg gtggagtccg gcgtcacaga tttcccgcca tgctcgtgcg gcggcccgaa
    18241 ccgtgctgct caccggaccg ctccggcgac tcggttccac cctgttgtcg cgcaccgccc
    18301 cgctgctccg catcgccctg tcgcaccgtg gtgtttccgt tcccgcccat gtccgaggtg
    18361 gtctgccgca cgtcggaggc accaccgcgc acctgcgtcg cgccctctct cacctggttg
    18421 accccgtccg tcactccgga cacggcaccg gtgagctcac gtgttcggtc cagcgcgacg
    18481 ttgacggcgt caccggtacc gcgcggacca tcgccactgg cgacctcctg aatcctggcg
    18541 agtgaggttc cggtggattt gactccctcg atcacctgct tcacgccctg gtagatccgg
    18601 atgatcgcct ggatcatgtc catgatcatg aacacgatgt cgatgcactg gatcacgatg
    18661 cgaaccgcgt tggcccagcc cccgacaggc acccaggccg tgcaagccgc ctggatcagc
    18721 cggttcacga gcttgtcgat cagctccagg atcttcgagc agagcatctt cgaggtatcg
    18781 gcggccttgg tgaaagccgt gctcaccaga tcggccgccg ccgcgtcggc ctccagcgcg
    18841 accgtccaac caccgaccat catggactcg aaagccgcag cggcggcacc gtcccagctc
    18901 tgccgcagat cgctgacacc gtggttgagg ttgcgccgca ccgcccgcag cgactcgcct
    18961 atgtcgttcc acgccttggc gttctgctcg atcttggcga agtcaccggt gatgggcgag
    19021 atcaacgact cgacgaggtt ctgccccgcg acctgctcgt agatccagtt gaccccctgg
    19081 acctgccagc tcgcgtcctg gatggccgat ttcagggttt ccgagtccgc ctgcccggtg
    19141 cgctgttcga gcttcgcgat cggatcgtcc acatcggcga atgccattcg tccccctcgt
    19201 aagactgccc cgtaatggct cgcaccggcc ccggccccgg gaaatctccc gtggtcgctc
    19261 ctttcggagc ccgacacggt gatggggccg accggtgctg tcgatcgttc tgacgccgag
    19321 tgctcagggc cgcatcccgc tcagggctgt ctctatgccg ctgagcagct gttcgatctc
    19381 gcgttcacgt tcttcgtact cggcggccgt gttgtccagc tcctccctga cccggagcag
    19441 cttggcgtgc gccaggcgca gggtttcgga gtagagcgcg gtggccccct gcacgaccgg
    19501 gatcagggac gccatgacgc cggtgaaacc gctggtgtcc gaagcggtct cgttggcgta
    19561 gctctcgata ccgttgaacg actcggcgtt gcgccgcaac agaccgccgt agtcgcggag
    19621 ccgcgacggt acggcttcga ctctctccga caccgtttcc ccctctgcgg agccgttccg
    19681 gacgtggccg gacgcgtctc actcgttcgg accacgactg tgacgcgacc gcacgactta
    19741 cggttccggg agaaaccgat ttttcgagtc ggtggtggat cgagctttcc gctcagtgcg
    19801 ccacggagtc cagcaccagg cgcgagatcc gctcggcggc ctcgcactgt tcggtgccgg
    19861 cctcctgttc actgaccacg acctgcaggg tggctcccgt cacgtcggag tagacggtgc
    19921 agtcgttggc gtaggaggtt ccgctggcgg cgacggggaa gtcggagagc cgttcgccgc
    19981 cgagctggtc gaaaccgtcg ggctgggcgg cgaggagcac cgagtcgtcg gcctcgctgc
    20041 cctgctcggc cggaaagcgg cagccgcgca ccggaggatc gaagctgacc tcctccggct
    20101 gaccgttgcc caccgcgaac gcgggctcgc gcagctcggc gggctcgacc agcgagcaca
    20161 tccgctcggc ggagagttcg gccagcttgt cgcgctgctc c
//
