LOCUS       NZ_FPAT01000002        21230 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Actinopolyspora righensis strain DSM 45501, whole genome shotgun
            sequence.
ACCESSION   NZ_FPAT01000002
VERSION     NZ_FPAT01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinopolyspora righensis
  ORGANISM  Actinopolyspora righensis
            Bacteria; Actinomycetota; Actinomycetes; Actinopolysporales;
            Actinopolysporaceae; Actinopolyspora; Actinopolyspora alba group.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900116555.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,474
            CDSs (total)                      :: 4,407
            Genes (coding)                    :: 4,334
            CDSs (with protein)               :: 4,334
            Genes (RNA)                       :: 67
            rRNAs                             :: 5, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 27 of 73
            Pseudo Genes (incomplete)         :: 61 of 73
            Pseudo Genes (internal stop)      :: 12 of 73
            Pseudo Genes (multiple problems)  :: 20 of 73
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:10:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 525072
            Orig. end                         :: 546302
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FPAT01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21230
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="amglyccycl"
                     /region_number="3"
                     /rules="(DOIS or ValA or salQ or strH or strK1 or strK2 or
                     NeoL or SpcFG or SpcDK_glyc)"
                     /tool="antismash"
     cand_cluster    1..21230
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="single"
                     /product="amglyccycl"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21230
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11230](+)"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11230
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
     gene            215..547
                     /locus_tag="BM394_RS05860"
                     /old_locus_tag="SAMN04487904_102492"
     CDS             215..547
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017973419.1"
                     /locus_tag="BM394_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102492"
                     /product="type VII secretion target"
                     /protein_id="WP_092974822.1"
                     /transl_table=11
                     /translation="MGEQRFGVNTDEIRAHARNLQGVTDRIGTAQDAAGEVSLNGTDAY
                     GILCSPILTPLIGAIEVQGMAAIATANAAVEATATGIEGAAETYDAVDQHVSELLESVR
                     NELGEI"
     gene            549..1481
                     /locus_tag="BM394_RS05865"
                     /old_locus_tag="SAMN04487904_102493"
     CDS             549..1481
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017973420.1"
                     /locus_tag="BM394_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102493"
                     /product="hypothetical protein"
                     /protein_id="WP_092974825.1"
                     /transl_table=11
                     /translation="MSQDNPLVEAEPDSQKWEDGLMVVDFAVDSWRAIDNHDWGEAAIT
                     GGAAVVDGLATVANPFDALLTSTFAWMMEHVWPLPDMLDSLAGNHDQVQANAHTWANIS
                     DELKQAATEMQQAVDADTADWQGPAAESYRMFGSGEAKLIEGAAESAKAVGAAVSGAGT
                     AILIVRTTVRDIIASAMSELVTYLVRSSAAAGLSLGALTPLLIADGIRIVAKWASRVSE
                     WLDKIVRAFRQLAEIVSKVKPLLTKVDELLQPNSRIGKGIQNWVSNRSLSDLTRGQEIA
                     RNTAAIGATADDQDYAKHEMGKHEHTDSA"
     gene            1538..2041
                     /locus_tag="BM394_RS05870"
                     /old_locus_tag="SAMN04487904_102494"
     CDS             1538..2041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017973421.1"
                     /locus_tag="BM394_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102494"
                     /product="DUF6346 domain-containing protein"
                     /protein_id="WP_139235151.1"
                     /transl_table=11
                     /translation="MRVVRDVLLVPIGILLFLAAFFVVLPYFGTGAAGSEVSARGTAVA
                     QQCRFAGPIAKSSAPKRENVIGFGWICRARVHWNDGSVETREVSGSQLTGEDVGNSVDV
                     VERQIDYSKGSDTRPQIYRADFEPHVLLAWGSVLATCLLGFVFAALGFSGLSRIFSKKG
                     VPVE"
     gene            2093..2611
                     /locus_tag="BM394_RS05875"
                     /old_locus_tag="SAMN04487904_102495"
     CDS             2093..2611
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017973421.1"
                     /locus_tag="BM394_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102495"
                     /product="DUF6346 domain-containing protein"
                     /protein_id="WP_245780004.1"
                     /transl_table=11
                     /translation="MRVVRVVRDVLLIPVGMVLFLSGIFVVIPLFGIGAAGSEVTARGT
                     AVAQQCRFDGPITESDAPERGYVVGFGYICQARVTWRDGTTEMWEVSGSQLKPGDVGEE
                     VAVVRRAIADGGAGTTTTRPEVFRADYEPNRWLGVPVMLAVMLFGIVVGGPACSRLYQT
                     FSGKESAVT"
     gene            complement(2644..3609)
                     /locus_tag="BM394_RS05880"
                     /old_locus_tag="SAMN04487904_102496"
     CDS             complement(2644..3609)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010315625.1"
                     /locus_tag="BM394_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102496"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_092974831.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-22,
                     bitscore: 75.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVEQARSTIVVVTWRGAEHIGACLDALARQRNHRLVVVDNASDD
                     GTSELLARHPSAPEVLRLPRNLGYAGGLAAAFPLVRTPYFGWLNDDAAPAPDWLATLED
                     SLDRDPSVGAATSRMWNRRGPLSQGVRLTCTGHGADTVAEDSTVAADNAGTGDEVFGFC
                     GGAALLRTSALSAVDGIPADYFCYYEDTDTSWRLRLAGYGITRTTAGCEHSHGCSSAPG
                     SARFHRWNERNRLLTLLRCAPVEIALRELLRFGAITLALPWRGLRQRSVPDAANFRVPL
                     RLGVLAEVAARAPTTLRQRRRITEACAVDRRRVWRSWAGK"
     gene            3695..4852
                     /locus_tag="BM394_RS05885"
                     /old_locus_tag="SAMN04487904_102497"
     CDS             3695..4852
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668095.1"
                     /locus_tag="BM394_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102497"
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="WP_342752644.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.1e-27,
                     bitscore: 89.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELVVVAEQLLAPVPGGTGRYTRELLRALAATAPPGWEPRTVVS
                     SDGDPARAEIEGVGGPDVLPLPRRPLTLAWQYGRWPRVSADSVHAPTPLFPPVAPGRGL
                     VVTVHDTVPWTHPETLTARGAVWHRRAVSRAARKADSLVVPTAAVAVDLRRHVPDATRI
                     EVIGEGVSTAVLSPGAAEKGHTAETGHTAEKGESAEETARRLRLPPRYLLAVGTIEPRK
                     GYEWLIRALAEPEAPDIPLLVVGAPGWGGVSLSDLAARHGFPPGRVRYLGPVEDSDLAV
                     LLRRSAALVAPSMAEGFGLPVLEAMAAGTPVVHSDAPALVELADGAGITVPRTDVGALA
                     LALREVLDDRRRSAGMIEAGRSRARWFDWNETARRVWRLHTVRPT"
     misc_feature    3725..3727
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5010..6140
                     /locus_tag="BM394_RS05890"
                     /old_locus_tag="SAMN04487904_102498"
     CDS             5010..6140
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019855396.1"
                     /locus_tag="BM394_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102498"
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="WP_092974836.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6.8e-21,
                     bitscore: 69.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIDATAVPADRGGVGRYVDSLLAALDTAGTPMSVACQPRDAELY
                     GRIAPHTRIVPAAESVVTRTARLSWEQTTLPRLARRLNARVVHSPHYTVPLVNTSASVV
                     TLHDATFFSDAPLHSPVKARFFRAWTRAALRRATVCVVPSRATSDELVRAAGANAARLR
                     VMYHGVDPERFHPPAPEEVTAVRRSLGLGDQPYVAFLGALEPRKNVPALIRGFARAVAD
                     RRDSPALVLAGQAGWDTEVENALESVPHRVRVIRAGYQPFDRLAGFLGGAALVAYPSIG
                     EGFGLPVLEAMACGAAVLTTRRLSLPEVGGDAVAYCGVAERGIAHGIGELLDDPVRRSE
                     LSSAAQQRAKEFTWADCADRHRAAYEHAEYLHRRDR"
     gene            6259..7146
                     /locus_tag="BM394_RS05895"
                     /old_locus_tag="SAMN04487904_102499"
     CDS             6259..7146
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948714.1"
                     /locus_tag="BM394_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102499"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_092975198.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.8e-16,
                     bitscore: 53.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRENDDVRDSHSYGEGLAVVTVTYSPGNTLDRFLETLPKATDRQL
                     SVILADNGSTDGSPERAALRPGVELARMGANLGYGSAANRGIAELSDDIGWVVVANPDV
                     EWSAGSLDELLAATERWPRGGAFGPLIREPDGSVYPSARSLPSLGRGAGHALLGGIWPD
                     NPFSRAYRQSTDSSAERTAGWLSGSCLLLRRAALDSVTGFDPRYFMYFEDVDLGDRLGR
                     AGWLNVYVPDSEVTHIGGHATARSSGWMLHEHHRSAYRYLADRNVGPTRAPLRVALRAA
                     LGARARFVARNSDR"
     gene            complement(7396..7893)
                     /locus_tag="BM394_RS22720"
                     /old_locus_tag="SAMN04487904_102500"
     CDS             complement(7396..7893)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222925.1"
                     /locus_tag="BM394_RS22720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102500"
                     /product="hypothetical protein"
                     /protein_id="WP_092974839.1"
                     /transl_table=11
                     /translation="MDPRNRADETLARARARGAFVVTPDSATSPMDAAQTVRIPRDSVR
                     DVERDDPSSTQLIPDSTGQSSQREQRSNQQEQQNPRREQPNQWDRGPRQGEQESTRQPE
                     PQRPEQQRSAQYHPSEQPTAEQPTTEQRAWPTYDSDSPTTPHRIDNAAYQHDPRRGPQR
                     FD"
     gene            8237..9334
                     /locus_tag="BM394_RS05905"
                     /old_locus_tag="SAMN04487904_102501"
     CDS             8237..9334
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017973427.1"
                     /locus_tag="BM394_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102501"
                     /product="NDP-sugar synthase"
                     /protein_id="WP_092974841.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.8e-12, bitscore:
                     42.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPDDHAPVGGAEAVVLVGGRGTRLRPLTLSAPKPMLPTAGVPF
                     LTHLLSRIRAAGVTRVILSTSYRAETFTEYFGDGSGMGLELEYVVEHEPLDTAGAIRNV
                     ADRLREPDVLVFNGDILSGVDLPALLGEHRADAADVTLHLVRVDDPGRFGCVPTDENGR
                     VTAFLEKTPNPPVDQVNAGCYVFRREVIDGIPAGRPVSVERETFPGLLESGARLHGYVD
                     SSYWLDLGTPAAFARGSADLVRGVAPTEALDGRVGESLVLPGASIAESASLGGGTTIGA
                     DCVVSERAALSAATLFDGARVEAGAEITDSVVGAGAVIGAGTVLRGAVVADGAVVGARC
                     ELLEGVRVWPGVELPAGGVRFSHDC"
     misc_feature    9536..9549
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.01"
                     /tool="antismash"
     misc_feature    9537..9550
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.07"
                     /tool="antismash"
     misc_feature    9538..9551
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.43"
                     /tool="antismash"
     misc_feature    complement(9546..9555)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     misc_feature    complement(9552..9570)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.3"
                     /tool="antismash"
     misc_feature    9566..9575
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.81"
                     /tool="antismash"
     misc_feature    9637..9651
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.76"
                     /tool="antismash"
     misc_feature    complement(9721..9736)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.2"
                     /tool="antismash"
     misc_feature    complement(9729..9745)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    9731..9746
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            10001..11230
                     /locus_tag="BM394_RS05915"
                     /old_locus_tag="SAMN04487904_102502"
     CDS             10001..11230
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: salQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102640.1"
                     /locus_tag="BM394_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102502"
                     /product="sedoheptulose 7-phosphate cyclase"
                     /protein_id="WP_092974847.1"
                     /sec_met_domain="salQ (E-value: 1.6e-159, bitscore: 525.7,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-ADH (E-value: 7.5e-09, bitscore: 29.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.1e-68, bitscore:
                     226.2, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIPTVNPTPTSITAAFDLPKPPGVSWRVRSQQVVDYEVSMTRGL
                     LSTSNSTFAHACGADGKRRTRCLVVVDDAVEQLYGERLRAYFSAWRIAHNWRVVPGDEN
                     TKQLDTALGLVDDMSSMGILRRAEKIVAIGGGVVLDVVGMTASLYRRGIPYIRVPTTLI
                     GQVDAGIGVKTGINHGQHKNRLGTYCAPETALIDPEFLRTVDRRHINNGLAEIIKMALI
                     KDSQLFDLLEATVASIDPETLADCGPAGGEILSRSIAGMLDELEPNLWEKVLERAVDYG
                     HTFSPSLELRADPPLLHGEAVAVDMAICVALARNRGLLSEQDADRALTLMNAAGLPLTH
                     PVFTAELLERALEDAVKHRDGYQRMPLTAGIGSAVFVNDITADELRAALSFVAHRDHRA
                     ADSDVLESAR"
     misc_feature    10247..10249
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11227..12318
                     /locus_tag="BM394_RS05920"
                     /old_locus_tag="SAMN04487904_102503"
     CDS             11227..12318
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012692.4"
                     /locus_tag="BM394_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102503"
                     /product="ROK family protein"
                     /protein_id="WP_092974850.1"
                     /transl_table=11
                     /translation="MRVPETFQDEHTGAASAAREAVVFDIGGTHFRCARWSPESGVRRM
                     WSKPSPSVLVHPDAGADELRTRLIDEICAGVGQEKGTTAGISLGAALDQRSGVVYASAP
                     LWGDSVTRFDLLAGLRERRPDVDWHLVNDVTAALLGLGETPRFDGFRRLLLVTVSSGIA
                     CRLVDRRLRTIPVDVCGLQGEIGHIPSGTTLAGNRVELNCDCGSPDHLAAFASGPGIRR
                     LAERLRELEPRRCAVSPLFDEDIEFESTFRRLLDDDDPLAREILDAATSPLADVLRTAW
                     CLDPSIDRIALTGGVVDGLGEHYHRALAERLTRDGVYLTSRFHPEWLAERLVRCDSSEA
                     DGLVGAGVAAVGSGRSARIGVES"
     gene            12315..13451
                     /locus_tag="BM394_RS05925"
                     /old_locus_tag="SAMN04487904_102504"
     CDS             12315..13451
                     /NRPS_PKS="Domain: PKS_ER (21-187). E-value: 3e-08. Score:
                     25.1. Matches aSDomain:
                     nrpspksdomains_BM394_RS05925_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019845.4"
                     /locus_tag="BM394_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102504"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_175529979.1"
                     /sec_met_domain="ADH_N (E-value: 2.5e-12, bitscore: 41.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGNAQPRNNALVRAGARVTVRQRPTPVPAAGELVVATEVAGLCG
                     TDIQILRGSRKESASVLGHEGIATVVSVGEGIRDSFSPGDAVVINPTHPNDPGFLLGHN
                     VDGLLQRRTLVPATATRAGLVLGLDRRPEAELAALVEPLAVVNYALRALSRFRPSTLLV
                     VGDGTIGQLAVRSAARWATTVKRTVLVHHGESGRQWTLRSGLPPDDSLVDGEDMTGVLR
                     EGPVGVLLATPRESTGPCLERVLRSVGDGSVIDVIGGVPPGLTVKSLPGTDLAGIRAAN
                     LAGRPDVPLTAERTATTGSRINLFGHRGVSNAHLGTAVSELVRSPERYRELITHIGDLE
                     YASRIMSDLARGNERIADGRRVIKLAVRVSPTCRKGDD"
     aSDomain        12378..12875
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM394_RS05925_PKS_ER.1"
                     /evalue="3.00E-08"
                     /label="BM394_RS05925_PKS_ER.1"
                     /locus_tag="BM394_RS05925"
                     /protein_end="187"
                     /protein_start="21"
                     /score="25.1"
                     /tool="antismash"
                     /translation="RQRPTPVPAAGELVVATEVAGLCGTDIQILRGSRKESASVLGHEG
                     IATVVSVGEGIRDSFSPGDAVVINPTHPNDPGFLLGHNVDGLLQRRTLVPATATRAGLV
                     LGLDRRPEAELAALVEPLAVVNYALRALSRFRPSTLLVVGDGTIGQLAVRSAARWATTV
                     KRT"
     gene            13451..14218
                     /locus_tag="BM394_RS05930"
                     /old_locus_tag="SAMN04487904_102505"
     CDS             13451..14218
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (14-168). E-value: 3e-07. Score:
                     22.4. Matches aSDomain:
                     nrpspksdomains_BM394_RS05930_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385522.1"
                     /locus_tag="BM394_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102505"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_092974856.1"
                     /transl_table=11
                     /translation="MTQSDDESPAGKRALVVGGSTGIGRGIADAWAAEGMDVVVLSRSE
                     PSDASSSNLRWEPLDLLDAAKTKERLADLAVDPLLAVCFSAVDYGAKRAPLGEVTEAEW
                     RTQFEINLHGLWLTLSATLPALRASAPGLFVGVSSEVVHNAGPMRSGYAATKAAGAALL
                     DSVRLEESTDEIRIVQVLPEGMVDTPGIRRRRSSDFDFSSYMTPDTFAPLAAELVRTRG
                     AEFQGDSLVVGSGGDWRSLSSGTPVSQSRRAGS"
     CDS_motif       13493..13582
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM394_RS05930_0001"
                     /evalue="5.00E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="BM394_RS05930"
                     /protein_end="44"
                     /protein_start="14"
                     /score="9.6"
                     /tool="antismash"
                     /translation="LVVGGSTGIGRGIADAWAAEGMDVVVLSRS"
     aSDomain        13493..13954
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM394_RS05930_PKS_KR.1"
                     /evalue="3.00E-07"
                     /label="BM394_RS05930_PKS_KR.1"
                     /locus_tag="BM394_RS05930"
                     /protein_end="168"
                     /protein_start="14"
                     /score="22.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVVGGSTGIGRGIADAWAAEGMDVVVLSRSEPSDASSSNLRWEPL
                     DLLDAAKTKERLADLAVDPLLAVCFSAVDYGAKRAPLGEVTEAEWRTQFEINLHGLWLT
                     LSATLPALRASAPGLFVGVSSEVVHNAGPMRSGYAATKAAGAALLDSVRL"
     gene            14215..15048
                     /locus_tag="BM394_RS05935"
                     /old_locus_tag="SAMN04487904_102506"
     CDS             14215..15048
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013429.4"
                     /locus_tag="BM394_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102506"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_175529980.1"
                     /transl_table=11
                     /translation="MTGGNPAIGLAEWRLPVRGAEAVELAASYGVRGIQLDFGGSGRGV
                     PLDTPGRARSLRREANGSGVELLAVAGNLLNDIGLTAPERSRAARSARGAMIALLDSAV
                     ALGVRLVLVPSFRASTIDGPEELERTVSVLRWAAEEARTRNLVLANENVLSPTTAVELF
                     ERVGSDSFRLVLDTGNPDVEGTDVPGLVRTLGPRIADQVHLKDGPLGLGDEWRGSGEIR
                     ATELSRAFARSGISVNWLILENDYRVADPRVIGLDVAAARRFADRIVPTKTGDSG"
     gene            15048..15701
                     /locus_tag="BM394_RS05940"
                     /old_locus_tag="SAMN04487904_102507"
     CDS             15048..15701
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018189276.1"
                     /locus_tag="BM394_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102507"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_217643370.1"
                     /sec_met_domain="HAD_2 (E-value: 9.8e-22, bitscore: 72.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVFLSFSALLFDMDGTLVDSTVVVERTWRRFARRHGIDASEVLA
                     DAHGRPTGETVLRFAPDGVDVARETATLVAEEVEDIEGVVQVPGAAEFLRRVPESRMAV
                     VTSASRELAVRRMEAAGVPLPSVLVTADDISSGKPDPEGYLKAAELLGVPPSSTVVFED
                     AESGLLAAEAAGATPVVVGSHDRASAAGRIGIRDFHAISVAGFDEDERVGISFE"
     misc_feature    complement(15809..15818)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    15884..15896
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            15897..16853
                     /locus_tag="BM394_RS05945"
                     /old_locus_tag="SAMN04487904_102508"
     CDS             15897..16853
                     /NRPS_PKS="Domain: PKS_ER (1-178). E-value: 1.1e-09. Score:
                     29.8. Matches aSDomain:
                     nrpspksdomains_BM394_RS05945_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF028222.4"
                     /locus_tag="BM394_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102508"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_245780010.1"
                     /sec_met_domain="ADH_N (E-value: 6.2e-25, bitscore: 82.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.4e-16, bitscore:
                     53.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHEPAPGHCLVAVEHVGLCGTDLGFYTGTSSYLHTGRKSYPFVLG
                     HEWSGEVVLTGEGVTGLREGDRVSGHNFRRCGSCAVCAAGGTFHCPYRTEMGVVGEEPG
                     AASEYLSVPAETVHRIPDGVGNRAAALLEPCSASVHALRRLAVSGADSVAILGAGTLGL
                     AAAQLAVSRGASVTVLDPNPRLASLAAELGTDRVADPDEVRSGNYDVVVEASGASEAVR
                     QAIRLCGQNARLAQLGTPHGPVDAVPVDEAVGKNLVTHNVLSGADHWPRLLEEVASGNL
                     RLEPMVDREFSFHEADKAFERLNDSGRDRPKVLLNIR"
     aSDomain        15900..16430
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM394_RS05945_PKS_ER.1"
                     /evalue="1.10E-09"
                     /label="BM394_RS05945_PKS_ER.1"
                     /locus_tag="BM394_RS05945"
                     /protein_end="178"
                     /protein_start="1"
                     /score="29.8"
                     /tool="antismash"
                     /translation="HEPAPGHCLVAVEHVGLCGTDLGFYTGTSSYLHTGRKSYPFVLGH
                     EWSGEVVLTGEGVTGLREGDRVSGHNFRRCGSCAVCAAGGTFHCPYRTEMGVVGEEPGA
                     ASEYLSVPAETVHRIPDGVGNRAAALLEPCSASVHALRRLAVSGADSVAILGAGTLGLA
                     AAQLAVSRGASVTV"
     misc_feature    16710..16712
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16879..17781
                     /locus_tag="BM394_RS05950"
                     /old_locus_tag="SAMN04487904_102509"
     CDS             16879..17781
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (17-171). E-value: 2.2e-27.
                     Score: 87.9. Matches aSDomain:
                     nrpspksdomains_BM394_RS05950_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.4"
                     /locus_tag="BM394_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102509"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_092974865.1"
                     /sec_met_domain="ADH_N (E-value: 8.1e-11, bitscore: 36.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVRIEGTGDPEVVGVERVEDPAVGAGDVLIEVVAAGVNPIDVA
                     TRNGTVPTGLPAVLGWDVSGTVRDTGEDVTRFGVGDPVIAMSAQAATGRGTHAEYVALP
                     ESLLAPAPRELDQVEAAALPLAGLTASQTVTELGSPSNGAEELLVVGAQGAVGSLVVQL
                     ARLNGWRISTFVRPSDVTRKPPRGVLRQYSEEHPPPPAGFSAVVDTAGVPEHLRSVCDE
                     GRYLTTTPFAQPEPSRGVRIVLIGVEQDGDELARLGTLVDEGSIEPGKPSAVVDFERAD
                     WAHRTLENGGTRGKLILVP"
     aSDomain        16930..17391
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM394_RS05950_PKS_ER.1"
                     /evalue="2.20E-27"
                     /label="BM394_RS05950_PKS_ER.1"
                     /locus_tag="BM394_RS05950"
                     /protein_end="171"
                     /protein_start="17"
                     /score="87.9"
                     /tool="antismash"
                     /translation="ERVEDPAVGAGDVLIEVVAAGVNPIDVATRNGTVPTGLPAVLGWD
                     VSGTVRDTGEDVTRFGVGDPVIAMSAQAATGRGTHAEYVALPESLLAPAPRELDQVEAA
                     ALPLAGLTASQTVTELGSPSNGAEELLVVGAQGAVGSLVVQLARLNGWRI"
     gene            17903..19087
                     /locus_tag="BM394_RS05955"
                     /old_locus_tag="SAMN04487904_102510"
     CDS             17903..19087
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="BM394_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102510"
                     /product="acyltransferase"
                     /protein_id="WP_245780011.1"
                     /transl_table=11
                     /translation="MRFLAALAVFGFHSSLQIPANSVFAHDGVADTYQKIMSQAGAAGV
                     TFFFVLSGFVMTWSYKPHDRNVDFWRRRLVKIYPNHVVTWAVALLLFAAVYTHPYQAVA
                     NLFLVQAWIPEYDTYLSVNPPSWSLSTEVAFYLLFPLVFAVARKIREQYLWWFVWLTVA
                     LVAITALVAYVLLPEHPRPPDGLPISTYQYWVNYVFPPLRLFDFFLGILLARIVLAGRW
                     VRLGIGPLVLALLGCYTVSLFVPYLYGMRAVCIVPLALLIPAIATSDVRGERSFLRGRT
                     MVWLGEISFAFYLVHAIVLVTGRELLGDSYFGTPLATGVLLLYLVLSILLAWALYEFVE
                     KPTTKHWSKPKKKGSGKRNSAAAESLGAGGSRNERAVDSAVGENESRSSATADR"
     gene            19148..20365
                     /locus_tag="BM394_RS05960"
                     /old_locus_tag="SAMN04487904_102511"
     CDS             19148..20365
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="BM394_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487904_102511"
                     /product="MFS transporter"
                     /protein_id="WP_139235152.1"
                     /transl_table=11
                     /translation="MRQGDLVYLRIVGLIVAIFGVGTSELMPSGMLEQLAGGLDISLAT
                     AGLSVTVYALTMAVGGPLVSAATTAMTRKRILLFLLGIFVLGNGIIAVAPGYAVVLVGR
                     VLTALTHGTFMAVSVVTAGSMVPAHKSGSAVAGVQLGINLATVLGVPFGTLLAQRLSWR
                     SSFAAVCVIAVLAAVLIMITVPDSGTPESSSVRSEVRAFSRWNVVTTVVATVLCSAGMF
                     TIITYLAPLLTRGTGFPAEVVPLLLLGYGAGSVIGNSVGGKLADKSLSAATAVLSGSLT
                     LTCLLCWLGTFSRSAMIPVLLVFALVTFALIPCLQTRVVKTAEEAPTLSLTVNMSAFGL
                     GAAIGSWYGGKIIELGVGVRTVPIGAAVLAIAGMSVIVITVLLERRKTDASRADSRNRT
                     AEKEVI"
     misc_feature    20476..20496
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 23.35"
                     /tool="antismash"
ORIGIN
        1 ggcgcaggca cagctcacgg accggatgcg ggaagcgatg gaacccgtcc tggggcagga
       61 cagcgagacg atggattcgg tgctgtccgg gatgcgcgac cggttcccgg tggaaccgga
      121 gcagggggac gccgcgtcca ctcgtggtgg ccaggacgcc gacgaggagc agtacgacga
      181 gtacgactgg ctgaaccagc gcaggaggtg aaccttggga gaacagcgct tcggcgtcaa
      241 caccgacgag atccgcgcgc acgcgcgcaa tcttcaggga gtgaccgacc ggatcggcac
      301 ggcgcaggac gccgctggtg aggtctcgct gaacggcacg gacgcgtacg ggattctgtg
      361 cagccccatc ctcacgccgt tgatcggtgc gatcgaggtg cagggcatgg cggcgatcgc
      421 gacggccaac gcggcggtgg aggcgacggc caccgggatc gagggagcgg cggagaccta
      481 cgacgccgtg gaccagcacg tctccgaact gctggaatcg gtacgcaacg agttggggga
      541 gatctgacgt gagccaggac aacccgctgg tggaggcgga gccggattcc cagaagtggg
      601 aggacggcct catggtcgtc gatttcgcgg tcgactcatg gcgcgcgatc gacaatcatg
      661 actggggcga agcggccatc accggcggcg ctgccgttgt ggacggtctc gccaccgtgg
      721 ccaatccgtt cgacgcgctg ttgacctcca cgttcgcctg gatgatggag cacgtctggc
      781 cgttgccgga catgctggac tccctggcgg gcaaccacga ccaggtgcag gccaacgcgc
      841 acacctgggc caacatttcg gacgagttga agcaagccgc gacggagatg caacaggcgg
      901 tcgacgccga cacggctgac tggcagggac cggccgccga gtcctaccgg atgttcggat
      961 ccggcgaggc caagctcatc gaaggagccg ccgagtcggc caaggcggtg ggtgctgcgg
     1021 tttccggtgc gggaacggcc atcctgatcg tccgcaccac cgtgcgggac atcatcgcct
     1081 cggccatgtc cgaactggtc acctatctgg tgcggtcctc ggcagcggct ggtctctcgc
     1141 tcggtgcgct cacaccgctg ctcatcgccg acggcatccg gatcgtcgcg aagtgggcca
     1201 gcagggtctc agagtggctg gataagatcg ttcgcgcctt ccggcagctg gccgagatcg
     1261 tgagcaaggt caaaccactg ctgaccaaag tggacgagtt gctgcagccg aattcgcgga
     1321 tcgggaaggg tatccagaac tgggtgagca accgttcgct gtccgatctg actcgtggcc
     1381 aggagatcgc tcgcaatacc gccgcgatcg gtgccacggc ggatgaccag gactacgcga
     1441 agcacgagat gggcaagcac gagcacaccg acagtgcgtg acccgtgaag ctttcgtagc
     1501 tcgcggagca gctatcgggc cagttcttgg agaaatcgtg cgtgttgttc gtgatgtgtt
     1561 gctggtgccg attgggatac tgctgtttct ggccgcgttc ttcgttgtac tgccgtactt
     1621 cggaaccggt gcggcgggga gcgaggtctc ggcgcgcggt accgctgtcg cgcagcagtg
     1681 ccgcttcgcg ggaccgatcg cgaagtcgag tgccccgaag cgggagaacg tgatcggctt
     1741 cggttggatc tgccgagctc gggttcactg gaacgacggc agtgtggaga cgcgcgaagt
     1801 gagcggttca cagctgaccg gggaggacgt cgggaacagc gtggacgttg tcgagcggca
     1861 gatcgactat tccaagggca gcgacacgcg tccgcagatc taccgtgccg acttcgaacc
     1921 ccacgtgctc ttggcgtggg gctcggtctt ggccacgtgt ctgttgggat tcgtgttcgc
     1981 cgctctcggg ttttccgggc tgtcccggat tttctcgaag aagggcgttc cggtcgagtg
     2041 agtggagttc gttcggttcg atcgccgaaa aacgggggag gaagagttcg gcgtgcgtgt
     2101 tgttcgtgtt gtccgtgacg tgttgctgat tcccgtcggg atggtgttgt tcctgtcggg
     2161 gatcttcgtg gtgatcccgt tgttcggcat cggggctgcc ggttcggagg tgacggcccg
     2221 gggtacggct gtggcacagc agtgccggtt cgacggtccg atcacggagt cggacgctcc
     2281 ggaacggggg tatgtcgtcg gtttcggtta catctgtcag gcgcgggtga cctggcggga
     2341 cggtacgacg gagatgtggg aggtctcggg ttcgcagctc aagcccggcg atgtcggtga
     2401 ggaggtcgcg gtggtccggc gggccatcgc cgacggcggt gccgggacca ccaccactcg
     2461 accggaggtg ttccgggccg attacgagcc gaacaggtgg ctcggggtgc ccgtgatgct
     2521 ggccgtgatg ctgttcggga tcgtggtggg agggcccgcc tgttcccggc tctaccagac
     2581 gttcagcggg aaagagtccg ccgtaacctg atctcccggc cgggaatgtg ggagtcccgt
     2641 ccctcacttc ccggcccagc tccgccagac gcggcggcga tcgacggcac atgcctcagt
     2701 gatcctgcgt cgctgccgca gggtcgtcgg tgcccgcgcg gccacttccg ccagcacccc
     2761 cagccgcagc ggcacccgga agttcgcggc gtccgggact gaccgctgtc gcagtccgcg
     2821 ccagggtagt gcgagggtga tcgcgccgaa ccgcagcagt tcccgcaggg cgatctccac
     2881 aggtgcacaa cgcagcagcg tcagcagccg gttgcgctcg ttccagcggt ggaaccgtgc
     2941 cgaccccggt gctgatgagc aaccgtgcga gtgctcgcag ccggcggtgg tccgcgtgat
     3001 cccgtacccg gccaaccgca ggcgccagga ggtgtcggtg tcctcgtagt agcagaagta
     3061 gtcggccggg ataccgtcga ctgccgagag tgccgaggtg cgcagcaggg ccgcgccgcc
     3121 gcagaacccg aacacctcgt ccccggtacc ggcattgtcc gctgccacgg tgctgtcctc
     3181 cgccacggtg tcggcgccgt gccccgtgca ggtcagccgc accccttggg agagggggcc
     3241 tcgccggttc cacatccggc tcgtcgccgc accgacactc ggatcgcggt ccaacgaatc
     3301 ctccagtgtg gccaaccagt ccggtgccgg tgcggcgtcg tcgttgagcc agccgaagta
     3361 gggcgttcgt accagcggga aggcagccgc gagaccgccc gcatagccga gattgcgggg
     3421 caggcgcagc acctcgggag ccgaggggtg tcgggccagc agttcgctcg tgccgtcgtc
     3481 ggaggcgttg tccaccacca ccagccggtg gttccgctgc cgggcgagcg cgtccagaca
     3541 agctccgatg tgctccgcac cgcgccaggt caccaccacg atcgtgctgc gggcctgctc
     3601 cacggtcatg tccgaagcct atcgcctcgc cccgatcacg gatgtggttg tctggcgggc
     3661 agcggtcggt gaagcgtgtg gactgggggc ggttgtgccg gaactggtgg tcgtggccga
     3721 gcagttactg gcgccggtac cgggcggcac cgggcgctac acccgtgagt tgctgcgcgc
     3781 gttggcggca accgcgccac ccggttggga gccgcgcacg gtcgtcagct ccgacggtga
     3841 tccggcccgc gccgagatcg aaggagtggg cggccccgat gtgttgccgc tgccgagacg
     3901 gccgttgacc cttgcctggc agtacggccg atggccccgg gtatcggccg attcggtgca
     3961 cgcccccacg ccgctgttcc cgccggtcgc gcccggccgt gggctggtcg tcaccgtgca
     4021 cgacacggtt ccctggaccc accccgagac actcaccgca cgcggtgcgg tctggcaccg
     4081 acgagccgtg tccagggcgg cgcgaaaagc ggactcgctg gtggttccca ccgcggcggt
     4141 ggccgttgac ctgcggcgac atgtcccgga cgccacgcgg atcgaggtga tcggcgaagg
     4201 ggtcagcacc gccgtgctct cccccggcgc agcggagaag gggcacacag ccgagacggg
     4261 gcacacagcg gagaagggcg agtcagcgga ggagacggca cgtcggttgc ggctgccccc
     4321 gagatacctg ctcgccgtgg gcacgatcga accccgcaag ggctacgagt ggctgatccg
     4381 cgcgttggcc gagccggaag ctccggacat tccgctgctg gtcgtgggcg cgcccggctg
     4441 gggtggcgtc tcgttgtcgg atctcgcggc tcgtcacggg ttcccgcccg ggagggtccg
     4501 gtatctcggt cccgtcgagg acagcgacct ggctgtgctg ctgcgccgct cggccgcgct
     4561 cgtggcaccc agcatggccg aggggttcgg gctgccggtg ttggaggcga tggcggccgg
     4621 aaccccggtg gtgcattccg acgctcccgc gctcgtggaa ctcgccgacg gagcgggcat
     4681 cacagtgccc aggacggacg tgggcgcgct ggcgctggca ctgcgcgagg tactcgacga
     4741 tagacgtcga tcggccggga tgatcgaagc cggcaggtct cgggcgaggt ggttcgactg
     4801 gaacgagacc gcccgccgcg tctggcgcct gcacaccgtg cgaccgacgt gacgaaccac
     4861 ccctgtcacc ccggcgctcg gtgagcgatc cccgcgacgg gtgggaccgc tgtcacattt
     4921 cggacttcgc gacggtggat ttcaccatcc cgccacaatg accgatgcct acctcctagg
     4981 ctgctcgcgt gcaccgagga gatccacacg tgcttatcga cgccaccgcc gtaccagcgg
     5041 atcgaggtgg cgtcggcaga tacgtcgatt ccctgctcgc cgcgctggac accgccggaa
     5101 caccgatgag cgtggcctgc cagccgcgcg acgccgagct ctacggcagg atcgcgccgc
     5161 acacccggat agtgcccgcc gccgagtcgg tcgtcacccg caccgcccgg ctctcctggg
     5221 agcagaccac cctgccgagg ctggccaggc gtctgaacgc ccgtgtggtg cactccccgc
     5281 actacaccgt tcccctggtc aacaccagtg cctcggtggt gaccctgcac gacgccacgt
     5341 tcttctccga cgcgccgctg cactcgccgg tcaaggcgcg gttcttccgc gcctggacca
     5401 gggcggcgct gcgtcgcgcc acggtttgcg tggtgcccag cagagcgacc tccgacgaac
     5461 tcgtacgtgc ggccggagcc aacgccgcgc gactgcgggt gatgtatcac ggggtggacc
     5521 ccgagcggtt ccacccgccc gctcccgagg aggtcaccgc cgttcggcga tccctcggac
     5581 tgggcgatca gccctatgtg gcctttctgg gagcgttgga gccgcgcaag aacgtcccgg
     5641 cgctgatccg cggtttcgcc cgcgcggtcg ccgaccgccg cgattccccc gccctggtgc
     5701 tggccggaca ggccggatgg gacaccgagg tggagaacgc gctcgaatcg gtgccgcacc
     5761 gtgttcgggt gattcgtgcc ggttatcaac cgttcgaccg attggccggt ttcctcggcg
     5821 gtgcggccct ggtggcttat ccgagcatcg gggaggggtt cgggcttccg gtgctggaag
     5881 ccatggcctg cggtgcggcc gttctcacca cccgaagact cagcctgccg gaagtgggcg
     5941 gagacgcggt ggcctactgc ggtgtggcgg aacgagggat cgcgcacgga ataggtgagc
     6001 tgctcgacga tccggtgcgt cgttccgagc tgtccagcgc ggcgcagcag cgtgccaagg
     6061 agttcacctg ggccgactgc gcggacaggc accgcgccgc ctacgagcac gccgagtacc
     6121 tgcaccggcg cgaccggtga acccgctata cccggtgaaa ccgctccgga ccgacgcgcc
     6181 gtgcggcgcg gtcgcgaccg agccgtcccg gaccgcgcgt gccggtcggc ggctcccgga
     6241 gccgatcggt tcgccgccat gcgtgagaat gacgacgtgc gcgactccca cagttacggc
     6301 gaggggctcg ccgtcgtcac cgttacctat tcgcccggca acacgctgga ccgtttcctg
     6361 gagaccctgc ccaaggccac cgatcggcaa ctcagcgtga tcctcgccga caacggttcc
     6421 accgacggct ctccggaacg cgccgcactg cgcccaggtg tggagctcgc gaggatgggc
     6481 gccaatctgg gttacggttc ggccgcgaat cgcggcatcg ccgagttgag cgacgacatc
     6541 ggttgggtgg tggtcgccaa tcccgacgtc gagtggagcg cgggcagcct cgacgagttg
     6601 ctggcggcca ccgaacgctg gccgcgcggc ggtgcgttcg gcccgttgat ccgggaaccg
     6661 gacggcagcg tctacccctc ggcccgctcg ttgccgtcac ttggacgagg tgccgggcac
     6721 gccctgctgg gcgggatatg gcccgacaat ccgttcagcc gcgcctaccg gcagtccacc
     6781 gacagctccg ccgagcgcac ggccgggtgg ttgtccggct cctgcctgtt gctgcggcga
     6841 gccgcgctgg attcggtaac cggtttcgat ccgcgctact tcatgtactt cgaggacgtc
     6901 gacctcgggg accggttggg ccgagcgggc tggctcaacg tgtacgtgcc cgacagtgag
     6961 gtgacgcaca tcggtgggca cgccaccgcg cgttcctcgg ggtggatgct gcacgaacac
     7021 caccgcagtg cctaccggta cctcgccgac cggaatgtcg ggccgacccg ggcgccgttg
     7081 cgggtcgcgc tgcgggccgc gctgggtgcg cgcgcccggt tcgtcgcgcg caactccgac
     7141 cgttagtaac agagcgttcc acgtcagctg ctgggatggt tccgtggcgg aacctctggc
     7201 acggctctcg ctgcggggag gcccgacatc gggtagcgac ctacacaacg tcgggccttc
     7261 ctcgcgagag ccgcacggga gaacccgcgg cggtgccgat cgcgagggtg gtcggagttc
     7321 ggctcgggag cgctgcggcg tacgaccgtc cggtgagctt ctttcccgag cgagggggtc
     7381 tgccgggacg ccgagtcagt cgaaccgctg tggaccgcgc ctgggatcgt gctggtaggc
     7441 ggcgttgtcg atccggtgcg gcgtggtggg agagtcggag tcgtaggtag gccaggcccg
     7501 ctgttcggtc gtcggttgct cggctgttgg ctgctcggac gggtggtact gcgctgaccg
     7561 ttgctgctcg ggccgttgcg gctccggctg ccgggtgctc tcctgctccc cttgtcgggg
     7621 accccggtcc cactggttgg gttgttcccg tcgggggttc tgctgttcct gctggttgct
     7681 ccgctgctcc cgctgggagg actgtcccgt cgagtccggg atgagctgag tggagctcgg
     7741 atcgtcccgc tccacgtcac gcaccgagtc gcgcgggatg cgcacggtct gcgccgcgtc
     7801 catcggtgag gtagcgctgt ccggtgtgac gacgaacgca ccccgtgccc gcgcacgagc
     7861 aagtgtttcg tcggctcggt tgcgggggtc catggtccct ctcaatgctg gccgttggat
     7921 tttcagccgc agcgtggccc gtccgtccgg tggattagcc ggtcccgagt cggccgatct
     7981 cacggctcga ccccgtggtg gcaggtccat cgtgacagag tgttcgacac cgcgtggttt
     8041 cgcattggcg gaccgtgccg accaggggcg ccataccagg tgggtgctgc tactgccaga
     8101 gtattcctca tggattccta cgtcagggtg atgagttggt cgatttcgac gaccgaatga
     8161 aatcgccctg tcggaggcga cgatcacccg tgcgagtcgt atcgagcgga ccctcggtcc
     8221 ggggaggtgc atggcgatga cgagtcccga cgaccacgcg ccggtaggcg gtgcggaggc
     8281 cgtggtgctc gtgggaggcc gaggtacgcg gttgcggccg ctgaccctgt ccgcccccaa
     8341 accgatgctg cccaccgccg gagtgccgtt cctgacccac ctgctctcgc ggatccgcgc
     8401 cgcgggggtc accagggtga tactcagcac ctcctaccgg gccgagacct tcaccgagta
     8461 cttcggtgac ggttccggca tggggctgga gctggagtac gtggtggagc acgagccgct
     8521 ggacaccgca ggtgcgattc gcaacgtggc ggaccggctg cgggaacccg atgtgctggt
     8581 gttcaacggg gacatcctct cgggagtgga cctgcccgcg ctgctgggcg aacaccgcgc
     8641 ggacgcggcc gacgtcacac tgcatctggt cagggtggac gatcccggcc ggttcggttg
     8701 cgtgcccacc gacgagaacg gcagggtgac cgctttcctg gagaagacgc cgaatccacc
     8761 ggtggaccag gtcaacgcgg ggtgctacgt cttccgtcgc gaggtgatcg acgggatccc
     8821 cgccggccgt cccgtctcgg tggagcgcga gacgttcccc gggctgctgg agtccggagc
     8881 gcggttgcac gggtacgtgg actccagcta ctggctggac ctgggcacgc ccgccgcttt
     8941 cgcgcgcggc tcggcggatc tggtccgggg cgtcgctccc acggaggcgc tcgacggccg
     9001 ggtgggggag tcgttggtgc tgcccggcgc ctcgatcgcc gagagcgcct cactgggggg
     9061 aggtaccacg atcggtgcgg actgcgtcgt gtccgaacgg gccgcgctct cggcggccac
     9121 gctgttcgac ggggcccggg tggaagccgg cgccgagatc accgacagcg tcgtgggggc
     9181 gggtgccgtg atcggggcgg gcacggtgct gcgtggtgcc gtggtcgccg acggtgccgt
     9241 ggtcggcgcg cgctgcgaac tgctcgaagg cgtccgggtc tggcccggcg tggaactgcc
     9301 cgccggcggg gtgcgcttct cgcacgactg ctgaactccg gggcgacgtg gttcaggccc
     9361 gcttgccgtt ccggggccct tcgtccttca tcgtcgatga gttcgtttcc gacgggttga
     9421 ccggcctctc gaaccacaca gtgggacgtg agggttcggg cgtagccgaa accacctgcc
     9481 ggttcgtcgg gtttcgttcc gatctgtgca ggagagaggc tcagtgctcc ggtcggtttt
     9541 taacccaaaa aaacatactg ttaagtattt ttttcttgtg gttcatcttc gggtaactct
     9601 tgacgtcggg tcgcgcgcgg agtgcctgct atagcttttt tgctgctaat tccgctggtc
     9661 tgtggcgtcg acgcaggctc gtggggcgtt cttcgcagct cactggaagc tgtagtgaat
     9721 agtgatttat gttacatttt tttgccttga acaaacaaac tgggcggttt tatttttgtt
     9781 gaggcggtgc ggcagccgga aaccccggag gcggccgcga gggtgtccgc ggtaacggga
     9841 gcgaagcccg ttcgcccgtg gagcccaccg gacgagcgat gggggactga tccgctccgt
     9901 tacctgtctc gcccgtgttc gcgggtcgag cgcgtgcggg gtgagtaccc cgtgatcgga
     9961 cagttgtacg aatcgacttt caacggattg tgagctctcg atgtccattc ccactgtcaa
    10021 tccaacaccg acgagcatca ccgccgcgtt cgaccttccc aagcccccgg gggtcagctg
    10081 gcgcgtccgg tcccagcagg tggtggatta cgaagtgagc atgacccgtg gactgctgtc
    10141 cacatcgaac tccacgttcg cccatgcctg cggtgccgat ggaaagcgca ggactcgctg
    10201 tctggtggtg gtggacgatg ccgtggagca gctctacggc gaacggttac gtgcctactt
    10261 ctcggcttgg cggatagcgc acaattggag agtcgtcccc ggcgacgaga acacgaagca
    10321 actcgacacg gctctcgggc tcgtggacga catgagttcg atgggcatac tccgccgtgc
    10381 cgagaagatc gtggcgatcg gcggcggagt ggtgctcgac gtggtcggta tgaccgcgag
    10441 cctgtaccgc cgaggtattc cctacattcg ggttcccacc actctgatcg gccaggtcga
    10501 cgcgggaatc ggcgtcaaga ccggcataaa tcacgggcag cacaagaatc gactcggaac
    10561 gtactgtgcg ccggaaacgg ctctcatcga ccccgagttc ctgcgcaccg tggatcgtag
    10621 gcacatcaac aacgggctgg ccgagatcat caagatggct ttgatcaagg actcccagct
    10681 gttcgacctg ctcgaagcca ccgtcgcgtc gatcgatccg gaaacgctcg ccgactgtgg
    10741 tccggccggt ggtgagatcc tgtcccgttc gatcgcggga atgttggacg aactcgagcc
    10801 gaacctgtgg gagaaggtac tcgaaagggc cgtcgactac ggccacactt tcagtccctc
    10861 gctcgaactc cgtgccgacc ctccgctgct gcacggggaa gcggtggccg tggacatggc
    10921 catctgcgtc gctttggccc gcaaccgcgg cctgctgtcg gagcaggacg ccgaccgggc
    10981 actcacgctc atgaacgcgg cgggattgcc gctcactcat cccgtattca ccgcggagtt
    11041 gttggaacgt gcgctggagg acgccgtcaa acacagggat ggctaccagc gcatgccgct
    11101 gacggcaggt atcggttcag cggtgttcgt gaacgacatc accgccgacg agctgcgagc
    11161 ggcgttgtcg ttcgtggccc atcgcgatca tcgagcggct gactcggatg tgctggagag
    11221 cgcgcgatga gggtgccgga gacgttccag gacgaacata cgggcgccgc gagtgccgcg
    11281 cgtgaggccg tggtgttcga catcggtggt actcacttcc ggtgtgcccg ttggtctccc
    11341 gaatcgggag tgcgtcggat gtggtccaag ccttcgccga gcgttctcgt tcacccggac
    11401 gcgggcgccg acgaacttcg aacgcggctg atcgacgaga tatgcgccgg ggtgggccag
    11461 gaaaagggca ccacagccgg tatctcgttg ggagcggcgc tggatcagcg cagtggtgtg
    11521 gtctatgctt ccgctccgct ctggggtgac agcgtgactc ggttcgacct gctggccggg
    11581 ttgcgagagc gaaggccgga cgtcgattgg cacctggtca acgacgtgac agcggcactg
    11641 ctcggactgg gggagacgcc gcggttcgac gggtttcgtc ggctcctcct cgttacggtg
    11701 agcagtggta tcgcgtgcag gttggtggat cgtcgactgc gaaccatccc ggtcgacgtc
    11761 tgcggtctcc agggggagat cggtcatatc ccctccggca ccactctcgc gggaaaccgg
    11821 gtggagctga actgtgactg cgggagcccg gaccatctgg ccgccttcgc ctcggggccc
    11881 ggcatccgcc ggctggccga acgactccgc gagctggaac cgcgacgctg tgccgtctca
    11941 ccgctgttcg acgaggacat cgagttcgaa agtacgttcc gccgactcct ggacgacgat
    12001 gatccgctcg ctcgggagat cctcgacgcg gccacgtcgc cgttggcgga tgtactgcga
    12061 actgcctggt gcctggaccc ctccatagat cggatcgcgc tcaccggggg agtcgtggac
    12121 ggtctcggcg agcactatca ccgcgcgctg gctgagcggt tgaccaggga cggtgtctac
    12181 ctgacgagtc gattccaccc ggaatggcta gccgagcgcc tcgtgcgctg cgacagttcc
    12241 gaggccgatg gcctggtggg agccggtgtc gccgcggtcg gatccggacg ttcggccagg
    12301 atcggggtgg aatcgtgacg ggaaacgcac aaccccgcaa caacgcactc gtccgagcgg
    12361 gagctcgcgt cacggtacgg caacgtccga ccccggtccc ggccgcgggc gagttggtgg
    12421 tggccaccga ggtcgcggga ctctgcggca ccgatatcca gatactgcgc ggttcgcgga
    12481 aggaatcggc ctccgtgctg gggcacgaag ggatagcgac ggtggtctcg gtcggagagg
    12541 ggatccggga ctcgttctcg ccgggggatg ctgtcgtgat caaccccacc catccgaacg
    12601 atccgggttt cctcctcgga cacaacgtgg acggattgtt gcagcgacgg accctcgtgc
    12661 ccgccaccgc gacacgagca ggcttggtcc tcggactgga tcggcgcccc gaagccgagc
    12721 tcgccgcgct ggtggagcca ctggcggtgg tcaactacgc gctacgggcg ctgagccggt
    12781 ttcggccgtc gacactgctg gtggtcgggg acggaaccat cgggcagctg gccgttcgct
    12841 cagccgcaag atgggcgacg accgtgaagc ggaccgtgtt ggtgcaccac ggtgaatcgg
    12901 gcaggcagtg gacactgcgc tccggacttc cacccgatga ctctctcgtg gacggcgagg
    12961 atatgacggg ggtgctgcgc gaggggccgg tcggagtcct actggccacc ccgcgggaga
    13021 gcacggggcc ttgcctggaa cgagtgctgc gttccgtcgg agacggttcg gtcatcgacg
    13081 tcatcggcgg agtacccccc ggacttaccg tgaaaagcct tcccggaacc gatctggcgg
    13141 gaatccgggc ggcgaacctc gccgggcgac ccgatgtccc cttgactgcc gaacgcaccg
    13201 cgacaacggg aagtcggatc aacttgttcg gccatcgggg ggtgtccaac gctcacctcg
    13261 gcacggctgt ctccgaactg gtccgcagtc cggagcggta ccgggagctg atcacccata
    13321 tcggggatct cgaatacgcg tcacgaatca tgagcgacct cgcccgcggc aacgagcgaa
    13381 tcgccgatgg ccgaagagtg atcaagctgg ctgtccgggt gtcaccgacc tgtcgaaaag
    13441 gagacgactg atgacgcagt ccgatgacga atcccccgcg gggaagcgcg ccctggttgt
    13501 cggcggctcc accggtatcg gcaggggaat agccgacgcc tgggccgccg aaggaatgga
    13561 tgtcgtcgta ctcagccgaa gtgaaccctc cgatgcgtcg agctcgaacc ttcgctggga
    13621 accgttggac ctcctcgatg ccgcgaagac gaaggagcgg ctcgccgacc tcgcggtcga
    13681 tccgttgttg gcggtgtgtt tctccgccgt cgactacggg gcgaagcgcg ctccgctcgg
    13741 cgaggtcacc gaagcggaat ggcgaaccca gttcgagata aacctccacg ggttgtggct
    13801 gaccctgagc gcgacgctgc ccgcgttgcg tgcctcagct ccggggctct tcgtgggggt
    13861 ttcctccgaa gtcgtccaca atgccggacc gatgcggtcc ggctacgccg cgacgaaggc
    13921 ggcaggggct gccctgctcg attcggttcg gttggaggag agcacggacg aaatccggat
    13981 cgttcaggtg ctgcccgagg ggatggtgga cacccccggc atacgccgca ggcggtcctc
    14041 ggatttcgac ttcagctcct acatgactcc cgacaccttc gcgccgctcg ccgctgagct
    14101 cgtgcgaacc aggggagccg aattccaggg agacagcctc gtggtcggtt ccggaggcga
    14161 ctggcgctcg ctgtcctcgg ggactcccgt ctcgcagagt cggagagcgg gatcgtgacc
    14221 ggcgggaatc cagcgatcgg gctggccgag tggcgtctgc cggttcgtgg ggccgaagcg
    14281 gtcgagctgg ccgcctccta cggtgtccgg gggatccaac tcgacttcgg aggttcgggg
    14341 cgtggggtgc cgctggacac ccccggcagg gcgcgctcgc ttcgccggga agccaacggt
    14401 tcgggagtcg agttgttggc ggtggcggga aacctgctca acgacatcgg cctcaccgcg
    14461 ccggagagaa gccgggcggc acggagtgcc cgcggcgcga tgatcgcgtt gctcgactcg
    14521 gccgtggctc tcggcgtgcg actggtcctt gtgccgagct ttcgtgccag cacgatcgac
    14581 ggtccggaag agttggagcg gacggtcagc gtactgcggt gggcggccga ggaggctcgg
    14641 acccggaacc tggtgctggc caacgagaac gtgctgtcgc ccacgacggc ggtcgaactg
    14701 ttcgagcggg tcggatcgga ctcgttcagg ctcgtgctgg acaccgggaa cccggacgtg
    14761 gaagggacgg acgtaccggg actcgtccga accctggggc cgcgtatcgc ggaccaggtt
    14821 cacctgaagg acgggccgct cggactcgga gacgagtggc gtggttccgg agaaatccgc
    14881 gccactgaac tgtcgcgcgc attcgcgcga agcgggatat cggtgaactg gctgattctc
    14941 gagaacgact atcgcgtcgc cgatccccgt gtgatcggcc tcgatgtagc ggccgctcgt
    15001 cggttcgcgg atcggattgt tccaaccaag accggagaca gcgggtgatg cacgtgtttc
    15061 tgagtttctc cgccctgttg ttcgacatgg acggtacgtt ggtcgactca acggtcgtgg
    15121 tcgaacgcac ttggcgacgt ttcgcccgta ggcacggtat cgacgcctcg gaagtgctgg
    15181 ccgacgcgca cgggcgcccc accggtgaga ccgtgctgcg tttcgccccc gacggggtgg
    15241 acgtggcgcg tgagaccgcg accctcgtgg ccgaggaagt cgaggacatc gagggtgtgg
    15301 ttcaggtgcc gggggcggcg gagttccttc gccgcgttcc cgaatcccgc atggcggtgg
    15361 ttacttcagc cagccgcgag ctggccgtac ggcgaatgga ggcagcgggt gtaccactcc
    15421 cgagcgtact ggtgaccgcc gacgacatct cctccggaaa accggacccc gagggctacc
    15481 tcaaggcggc ggaactgttg ggagtgccgc cgtcctccac ggtcgtgttc gaggacgccg
    15541 aatccggcct gttggcagcg gaggcggccg gcgcgactcc ggtggtcgtg ggatcccacg
    15601 accgcgcctc cgccgcggga cgtatcggaa taagggattt ccacgcgata agtgtcgccg
    15661 gattcgacga ggacgagcgg gtcggaatat cgttcgaatg attactcgaa tcctgcctgt
    15721 tcggttccgc tgagtcggac cgatcgttga ggtcggtgac gattcttcgc atggattgac
    15781 tcgtaaaccc tttgtgggga gacatgaccc aaaaaacatc ttccggtcgg ctgccgactg
    15841 ccacggtttc tctcgtgttg gaatctccgg gacggctcgc gcatcgcagt ttgccagtgc
    15901 acgagcccgc gccgggccat tgtctcgtcg cggtggaaca cgtcggtctc tgcggcacgg
    15961 atctgggttt ctacacgggt accagtagct acctgcacac cggtcgcaag agctatccgt
    16021 tcgtactcgg ccacgagtgg agcggagaag tcgtcctcac cggcgagggc gttaccggtc
    16081 tgcgggaagg cgatcgggtg tccgggcaca acttcagacg ttgtggaagc tgtgccgttt
    16141 gtgcggcggg cgggaccttt cactgcccgt accgcaccga gatgggggtt gtcggcgagg
    16201 agccgggcgc cgcctcggag tatctctccg tgcccgccga gacggtccac cggatcccgg
    16261 acggagtcgg taatcgtgct gctgccctgc tggagccgtg ctccgcatcg gtacacgccc
    16321 tgcgacggct cgcggtttcc ggagcggaca gcgtcgcgat cctcggagcc ggaacactcg
    16381 gcttggcggc cgcccagttg gccgtttcgc gaggcgcgag tgtgacggtt ctcgacccca
    16441 acccccggct cgcctccctg gcagccgaac tggggacaga ccgcgtcgcg gatcccgacg
    16501 aggtgcgcag cggtaactac gacgtggttg tcgaggcatc cggtgcgagc gaggcggtgc
    16561 gtcaagcgat ccggctctgc ggccagaacg cccggttggc gcaactcggt acgccccacg
    16621 ggccggtcga tgccgtcccc gtcgacgaag cggtggggaa gaacctggtg acgcacaatg
    16681 ttctgtccgg cgcggaccac tggccgcgat tactggaaga ggtcgcttcg ggaaatctcc
    16741 ggttggaacc gatggtagat cgagagttct ctttccacga agcggacaag gcattcgaga
    16801 ggctgaacga cagcgggcgg gaccgtccga aagttctgct gaatatccgt tgaaatacat
    16861 accacgaacg gggctgaaat gcgtgcggta agaatcgagg gaaccgggga tccggaggtt
    16921 gtcggtgtcg agcgggtcga ggaccccgct gtcggtgccg gtgacgttct gatcgaggtg
    16981 gtagccgccg gggtgaaccc gatagatgtg gcgacgcgaa acggcacggt gccgaccggc
    17041 ctcccggccg tgctggggtg ggacgtctcc gggacggtgc gcgatacggg tgaggacgtg
    17101 acgcggttcg gcgtggggga tccggtcata gccatgtccg cgcaggcagc caccggacgg
    17161 ggaacccacg ccgagtacgt ggcgctgccc gagagtctcc tggcgcccgc accacgtgag
    17221 ctcgatcagg tggaagcggc tgccttgccg ttggcgggac tgaccgcttc ccagaccgtg
    17281 accgagctcg gttccccctc caacggcgcg gaggaattgc tggtggtggg ggcacagggc
    17341 gcggtgggca gcctcgtggt tcaactggcc cggctgaacg gctggcggat ctcgaccttc
    17401 gtgcggccga gcgacgtgac ccggaagccg ccccggggtg tgctgcgcca gtactccgag
    17461 gaacatccac cacctcccgc cggtttctcc gcggtcgtcg acaccgcggg agtcccggaa
    17521 cacctccggt cggtgtgcga cgaggggagg tacctcacga cgacaccgtt cgcgcaaccg
    17581 gaaccgagtc gaggagtgcg gatcgtgctg atcggtgtgg aacaggacgg tgacgaactc
    17641 gcccgactcg gaactctcgt cgacgaggga agtatcgaac cgggtaaacc ctcggctgtc
    17701 gtcgacttcg agcgagcgga ctgggcgcat cggacactcg aaaacggtgg aaccagggga
    17761 aaactgattc tggtcccctg agaaaccccg ggcggtgctc ctggaattac tacgcgaaag
    17821 aagtgaaatt atgacggttg tggaagaaaa agccaagtcg gaagcggatc ggcgcagatc
    17881 tcgattaccc tccttgaccg ggatgcgctt cctcgcggcg ctggcggttt tcgggttcca
    17941 ttcctcactg cagatacccg ccaattcggt gttcgcgcac gacggtgtgg ccgacacgta
    18001 ccagaagatc atgtcccagg ccggtgcggc gggcgtcacg ttcttcttcg tgttgagcgg
    18061 cttcgtgatg acctggtcgt acaagccgca cgaccgcaac gtggacttct ggcgccgcag
    18121 gctggtcaag atctacccga atcacgtggt gacgtgggct gttgcgctgc tgctgttcgc
    18181 ggccgtctac acgcacccct accaggccgt ggccaacctg tttctcgtgc aggcgtggat
    18241 cccggagtac gacacctacc tcagcgtcaa tccgccgagc tggtcgttgt ccaccgaagt
    18301 ggccttctac ctgctctttc cactggtgtt cgcggtagcg cgcaaaattc gcgagcagta
    18361 tctgtggtgg tttgtctggc tgaccgtggc gctggtggcg atcaccgccc tggtggccta
    18421 cgtcctgttg ccggagcatc cgcgtccacc ggacggcctc ccgatctcca cttaccagta
    18481 ctgggtgaac tacgtctttc caccgctgcg gctgttcgat ttcttcctcg gcatactgct
    18541 ggcccgcatc gtgctggccg gaaggtgggt gcgtctcggg atcggtccac tggtgttggc
    18601 gctgctcggt tgctataccg tttccctgtt cgtgccttac ctctacggca tgcgcgcggt
    18661 gtgcatcgtt ccgctggcac tgctgatccc cgcgatcgcg acgtccgatg ttcgaggtga
    18721 gcgttcgttc ctccgcggcc gcaccatggt atggctcggt gagatatcct tcgccttcta
    18781 cctggtgcac gccatagtgc tcgtcacggg acgcgagttg ctgggggaca gttatttcgg
    18841 gactccgttg gcaaccggag ttctcctgct ttatctggtg ctgagtattc tgctcgcctg
    18901 ggcgctgtac gagttcgtgg aaaagcccac gacgaaacac tggtcgaaac cgaagaagaa
    18961 gggttccgga aagaggaact cagctgccgc ggaaagcttg ggggctgggg gttcccggaa
    19021 cgagagggca gtggattccg ctgtcggaga aaacgagagc aggagctcgg cgaccgcgga
    19081 tcggtgaccg ggcggaaatt cggttgtcgg ctgaatcgcc tcggctgttc tcgtggaacg
    19141 ttacgagatg cgacaagggg acctcgtgta tctgcggata gtcggtctga tcgtggccat
    19201 cttcggggtg ggtacgtcgg aactaatgcc gagcggaatg ctcgaacagt tggcgggagg
    19261 actcgacatc agtctggcga ccgccggact gtccgtgacc gtttatgccc tgacgatggc
    19321 tgtcggtggt ccgctggtat cggcggccac cacggcgatg acgcggaaga ggatcctgct
    19381 gttcctgctc gggatcttcg tgctcggcaa cggcatcatc gccgtggccc ccggatacgc
    19441 ggtggtcctg gtcggccggg tgctgacggc tctcacccat ggaaccttca tggccgtcag
    19501 cgtcgtcacc gcgggcagca tggtcccggc tcacaagtcc ggaagcgccg tggccggggt
    19561 gcagctgggc atcaatctgg caaccgtgct gggggttccg ttcgggacgc tgctggcaca
    19621 acggctcagt tggcgttcga gtttcgcggc ggtgtgcgtc atagcggtgc tggccgccgt
    19681 gctcatcatg atcacggtac cggactcggg cacgcccgag tcctcgagcg tgcggtccga
    19741 ggtccgggca ttcagcaggt ggaacgtcgt caccacggtg gtcgcgaccg tgctgtgctc
    19801 agccgggatg ttcacgatca tcacgtactt ggctccgttg ttgaccaggg gaacggggtt
    19861 tccggccgag gtggtccccc tgctgttgct gggttacggg gccggttccg tgatcggcaa
    19921 ctccgtcgga ggcaagctgg cggacaagtc cctgtccgcg gcgacggcgg ttctgtcggg
    19981 gtcgctgaca ctgacctgcc tcctctgctg gctgggaacc ttctcgcgaa gtgccatgat
    20041 tccggtgctg ctggtgttcg cgctggtgac gttcgcgctg attccgtgcc tgcagacgag
    20101 agtggtgaaa actgcggagg aggctccgac cctttcgttg accgtgaaca tgtcggcatt
    20161 cggtctgggt gccgcgatcg gttcctggta cggcggaaag ataatcgagc tcggtgtcgg
    20221 tgtgcggacc gttccgatcg gtgccgcggt tctcgcgatc gcgggaatgt cggtgatcgt
    20281 gataaccgta cttctggagc gcaggaaaac cgacgcctct cgtgccgatt cgcgaaacag
    20341 gacggcggaa aaagaagtaa tttgatttgg ttcgagtcgc aggaaatact gaaaagggag
    20401 cgatatgtcg tcctcggtaa ttggtgagag agcctactcg gcttattcga ggttaccctc
    20461 gctcaccggg atgagattca tagcggcggc tatggtgttc ttcttccatg cctcgctgac
    20521 ggatccgccg cagaaccctt atgcggaccc gttcgcgtcc gatctctatc agacgctctt
    20581 cagtaaagcg ggttggatgg gagtgtcctt cttcttcgtg ctcagtggct tcgtgctgac
    20641 gtggtcagcg cgttccaccg acacgatggg aggattctgg cgaaggcggc tggtgaagat
    20701 attcccggcg cacgtggtca cctgggcgct ggccatgatc ctgttcgccg ccgctgcctc
    20761 cgatccgcac cagtggttgc cgaacctctt cctgatccac tcctggttcc cgcagcacga
    20821 gatcttcatc agcgtgaacc cgccgagctg gtcgttgtgc agcgagctgc tcttctacat
    20881 gtgcttcccg ttcatcatca agggtgtcgt gcggatcagg caggaacgcc tctggtcgta
    20941 cgctgggctg atgatcctgg ggatggtggg tgtccaggtt ttcacccagt tcgtgcttcc
    21001 cgacaccccg cagacccccg aagggttccc ggtgtcggtc tggcagttct ggttcggtta
    21061 caacttccct cccgtgcgac ttttcgagtt cgtgctgggg atgctgctgg cgcgaatcgt
    21121 gatgtccgga atgtggttcc gctcgctcgg attcgttcac gcgacggtac tggcggttgc
    21181 cggatatgcg ctcgccatgg tcgtgccgtg gttgtacggg ctcaacgtgg
//
