LOCUS       NZ_FPAA01000006        25089 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Marininema halotolerans strain DSM 45789, whole genome shotgun
            sequence.
ACCESSION   NZ_FPAA01000006
VERSION     NZ_FPAA01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Marininema halotolerans
  ORGANISM  Marininema halotolerans
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Marininema.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900116235.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:20:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,453
            CDSs (total)                      :: 3,387
            Genes (coding)                    :: 3,359
            CDSs (with protein)               :: 3,359
            Genes (RNA)                       :: 66
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 28
            CDSs (without protein)            :: 28
            Pseudo Genes (ambiguous residues) :: 0 of 28
            Pseudo Genes (frameshifted)       :: 5 of 28
            Pseudo Genes (incomplete)         :: 25 of 28
            Pseudo Genes (internal stop)      :: 3 of 28
            Pseudo Genes (multiple problems)  :: 4 of 28
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:12:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 166922
            Orig. end                         :: 192011
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FPAA01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25089
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25089
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25089
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15089](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15089
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            1294..2637
                     /locus_tag="CHX35_RS18030"
                     /old_locus_tag="SAMN05444972_106165"
     CDS             1294..2637
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014544.4"
                     /locus_tag="CHX35_RS18030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106165"
                     /product="HYR domain-containing protein"
                     /protein_id="WP_176392008.1"
                     /transl_table=11
                     /translation="MPAFTYTGALQTLTIPGGVCRVTIQAQGAAGGSNLFYSSFDEDGG
                     GLGASIQGTFAVAPGDVLSIVVGGQGGDTPDINEPNGGGGGGGGSFVWQGSSFGELNPS
                     TLLVAAGGGGGGAGFDFGEDDSGSASGGSGMIGSIGQDGGNAAGGFGAGGTAGNGGSGG
                     NGGMMAGLGGGGGGGGGINFNGGNGFGNAGGDGGVSIVAGGAGGAGGVGAMGDYIGGDG
                     GFGGGGGGSDRNGGGGGGFSGGGGGTGVGFFVAAGGGGGGGSFNGGTNPVHMEGVRAGN
                     GIVEIIYEAPTLTCSNITVANDRGACGANVTYNELETCPGLDVTCSPASGSFFSVGTTT
                     VTCTAMDTVGGSTTCRFIVTVIDTEPPEISGLNDIDVETNDPNGTVVTYPDPIVTDNCP
                     GEITVTCSPASGSFFPFGMTTVTCTATDPSGNTATETFTVFVTSSQEE"
     misc_feature    2776..2790
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.38"
                     /tool="antismash"
     gene            2858..3508
                     /locus_tag="CHX35_RS09690"
                     /old_locus_tag="SAMN05444972_106166"
     CDS             2858..3508
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020893.4"
                     /locus_tag="CHX35_RS09690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106166"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_091836972.1"
                     /transl_table=11
                     /translation="MINKKNLSLMVWLIVLVLGACTFLFMDRGQFNPETIRYVVLSYGV
                     WAPILYLLMHIVRPLFLVPATVLAVASGITFGPWWGTLLDASGSLAGAMVAFSLARWLG
                     KETVSRWLNQFTHWERWMVDEGFRTIVISRLIPFLPFDAISYGAGFSNIKVNDYFWATV
                     IGILPGAFVFNVLGYSLHDLFSPLFFASLGAALVLAISPWLFRRLRRNYVKQK"
     gene            complement(3569..3988)
                     /locus_tag="CHX35_RS09695"
                     /old_locus_tag="SAMN05444972_106167"
     CDS             complement(3569..3988)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024854.4"
                     /locus_tag="CHX35_RS09695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106167"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_091836974.1"
                     /transl_table=11
                     /translation="MSDRTQMTHDTIQAFQHVVHKLRRGIQQQLEENWGVADFVFLHQL
                     HTQGPSKGSDLSSELNVTNSHVTQHVNRMVKKGWISRHRSTDDKRIVELAITPAGTEVY
                     NEMVKRRFQYFQQLFHTLSDEELDSLLHLLQKLID"
     gene            4250..5938
                     /gene="ilvD"
                     /locus_tag="CHX35_RS09700"
                     /old_locus_tag="SAMN05444972_106168"
     CDS             4250..5938
                     /EC_number="4.2.1.9"
                     /GO_function="GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004435046.1"
                     /locus_tag="CHX35_RS09700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106168"
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="WP_091836976.1"
                     /transl_table=11
                     /translation="MSTNETKDLRIRSHVISEGANRVPNRAMLRATGFTDEDFQKPMIG
                     VASTWSEVTPCNMHIKELAEEAKRGAVEAGGAPMIFNTITVSDGISMGHEGMHYSLPSR
                     EVIADSIETVIGAERLDAYVAIGGCDKNMPGCMIAIGRTDVPAVFVYGGTIRPGKLDGK
                     DIDIVSAFEGVGQYNQGTIDREGLHEIECHACPGAGSCGGMYTANTMSSAIEALGMSLP
                     GSSSNPAETKEKLADCREAGAAAVELLRKGIYPKDIMTKEAFENAITVVMALGGSTNAI
                     LHLLAMAHSVDVDLTMDDFERVRERVPHIADLKPSGRFVMQDLYEAGGVPAVMKVLLEQ
                     GLLHGDCLTVTGKTIKENLAEAEPLRAGQEVIRPFDKPFRKTGPLVVLEGNLAPEGAVA
                     KVSGLKVNQLTGPARVFDSEEAATAAILSDQIKVGDVVIIRYEGPKGGPGMPEMLSITG
                     MLVGKGLGEKVALLTDGRFSGGSHGLVIGHIAPEAQVGGPIALVEDGDQVTIDSVKREL
                     SVALSPEELSRRRSAWQERPLPVRRGVLHKYSKLVSSASKGAVTD"
     misc_feature    complement(6220..6235)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.23"
                     /tool="antismash"
     gene            6305..6511
                     /locus_tag="CHX35_RS17275"
     CDS             6305..6511
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS17275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_140413592.1"
                     /transl_table=11
                     /translation="MLKPGQWTQRRAHLGAVRRKVGNPLVERYRMIAVTDQGISKLEYL
                     PSLFAARRQRYWVVPRTLRPNQL"
     gene            6599..8320
                     /gene="ilvB"
                     /locus_tag="CHX35_RS09705"
                     /old_locus_tag="SAMN05444972_106170"
     CDS             6599..8320
                     /EC_number="2.2.1.6"
                     /GO_component="GO:0005948 - acetolactate synthase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003984 - acetolactate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012685343.1"
                     /locus_tag="CHX35_RS09705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106170"
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="WP_245838749.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.1e-56, bitscore:
                     184.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.2e-52, bitscore:
                     168.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGSQSGKAESPKTEYTGSEILLRCLIEEQVDVVFGYPGGAVLPI
                     YDSLYEGGLRHLLARHEQGAIHAADGYARATGKPGVVIATSGPGATNLVTGIATAQMDS
                     IPMVCITGNVSQELMGTDAFQEADIMGITMPIVKHSYLVTDVCDLPRIVKEAFHLASTG
                     RPGPVLIDIPKDVANARDTFHYPKGVSIRGYQPTSSAHPLQLARLREVIAEAKRPVILA
                     GGGVVTAGAEKELITFAEQTQIPVITTLMGLGGFPGQHPLWLGMPGMHGTYAANHALLE
                     TDLLIGIGARFDDRVTMGRLDKFATKAKIVHMDIDPAEIGKNVNTFIPIVGDVKNVLQA
                     ANVDLPQSDSAAWIEKVTGWRESYPLCYRDSEDRLKPQWVIRHLYETTGGDAVVTTDVG
                     QHQMWVAQYFHFARPRSFISSGGLGTMGFGFPAALGAQLATPEQLVISVTGDGGFQMTN
                     QELAVASLANIPVKVVIINNQNLGMVRQWQEVFYHKRYSEVDLSGSPDFVKLTEAYGVK
                     AWRAKTKEEAITAWAEALAHPGPAVVDFWVAPDENVYPMVAPGKGLDEMIMGDEKA"
     gene            8317..8808
                     /gene="ilvN"
                     /locus_tag="CHX35_RS09710"
                     /old_locus_tag="SAMN05444972_106171"
     CDS             8317..8808
                     /EC_number="2.2.1.6"
                     /GO_function="GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018753046.1"
                     /locus_tag="CHX35_RS09710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106171"
                     /product="acetolactate synthase small subunit"
                     /protein_id="WP_091836980.1"
                     /transl_table=11
                     /translation="MRHVLSVLVNDQPRVLARVSTLLGRRNFNIESISVGESEEKGLSR
                     MVIVTHGDERTMEQVQKQLHKLIDVIKVHDLSNHPAVERELLLIKVEAGPAARMEISGV
                     VEPFRAAVVDVGSQNMMVQATGERAKLDALIELLRPYGIKEIARTGVTALSRSMVQGNS
                     "
     gene            8864..9871
                     /gene="ilvC"
                     /locus_tag="CHX35_RS09715"
                     /old_locus_tag="SAMN05444972_106172"
     CDS             8864..9871
                     /EC_number="1.1.1.86"
                     /codon_start=1
                     /gene="ilvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712070.1"
                     /locus_tag="CHX35_RS09715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106172"
                     /product="ketol-acid reductoisomerase"
                     /protein_id="WP_091836982.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.9e-10, bitscore:
                     34.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATVYYAKDADLKQLAGKTVAIIGYGSQGHAQAQNLRDSGVQVVI
                     GLRKGKSWEKAEKDGFIVLEVAEAVKRSEVINLLMPDETMAQVYKEEVEPNLKPEAALL
                     FSHGFNIHFNQIQPPPHIDVALIAPKGPGHLVRRVYTEGFGVPGLIAIHQDASGSAKAI
                     GLAYAEGIGATRAGVIETTFKEETETDLFGEQAVLCGGASELVKKGFETLTEAGYQPEI
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAEYGDYVSGKRVVGDASKAAMKEVLKEI
                     QDGTFAQQWITENKNGRQEFTRIRKEEGEHLLETTGEKLRETMAWINQKQSVKA"
     gene            10001..11563
                     /locus_tag="CHX35_RS09720"
                     /old_locus_tag="SAMN05444972_106173"
     CDS             10001..11563
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005829322.1"
                     /locus_tag="CHX35_RS09720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106173"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_091836983.1"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-98, bitscore:
                     323.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSRTVQFFDTTLRDGEQSPGVNLNVEEKVEIALQLEKLGIQVIE
                     AGFAASSAGDREAVRRVGEAVHTPIVVSLARAVDVDIDAAWDALKTATNPGVHIFLATS
                     PIHRQYKLNMTKEEILNQVEAAVRYAKRFFPHVEFSPEDGGRTELDFLCQVAERVIEAG
                     ADVLNIPDTVGYLSPQEYGNIFRHLKSHVNGIEKVKLSAHCHDDLGMATANTLAAIEAG
                     VEQVEGTINGIGERAGNAALEEVAMALATRSTYYGVKTNLQLAEIARTSRIVSKMTGMF
                     VPGNKAVVGANAFAHESGIHQDGMLKHASTYEIMRPETVGQADTRLVLGKHSGRHAFRD
                     KLVQLGYAFNDQQINHLFHRFKELTDRKKLIEDDDLVSLVEERIGDEEEVYSFETVQVA
                     YGNQSVPTASLRIKDNRDQRLLEEAACGNGSVDAIFKAIDRITNEAWHLEDYRIVSVTH
                     GKDALGEVYVKLSDGEESTVQGRGVSTDVLEASARAYIHGVNRLLARRNREKQPAGVGS
                     ISG"
     gene            11586..12704
                     /gene="leuB"
                     /locus_tag="CHX35_RS09725"
                     /old_locus_tag="SAMN05444972_106174"
     CDS             11586..12704
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712072.1"
                     /locus_tag="CHX35_RS09725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106174"
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="WP_091837093.1"
                     /transl_table=11
                     /translation="MTRPKRIAVLPGDGIGPEIVEEGVKVMKAAGERFGYHFEIDFGWI
                     GGSAIDRLKNPLPQETLTLCHQADAVLLGAVGGPRWDQHPPALRPEKALLGLRKELDLF
                     ANLRPTTLFPGLEDSSTLKPEVLKGVDFLVVRELTGGIYFGEKFTEDTPAGEKATDTLV
                     YSETEVERILRRAFDIAQLRGKKVTSVDKANVLESSRLWRKVADRVAKDYPDVELTHLL
                     VDNCAMQMIRRPADFDVVVTENMFGDILSDEAAILTGSIGLLPSASLGEGHQGLYEPVH
                     GSAPDIAGQGVANPIATILSVALMFRYSFHDDTVAKAIEGAVTDTLASGARTMDLVSTG
                     RLAYSTEEFGDKVVEALNKYQPDPTLPVEAMM"
     misc_feature    complement(12820..12833)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.28"
                     /tool="antismash"
     gene            12878..13246
                     /locus_tag="CHX35_RS09730"
                     /old_locus_tag="SAMN05444972_106175"
     CDS             12878..13246
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS09730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444972_106175"
                     /product="hypothetical protein"
                     /protein_id="WP_091836985.1"
                     /transl_table=11
                     /translation="MAINEGWLAHLHALNALERLYHEYWDLDLAEKVRSELARSVDLLG
                     SHVDKVPCPCGDTREDVTFYRSLLRHAEASVAERNLFPLPLVQEALTHHFTHKSEKHRC
                     IGRLIGREHDWVKGMETG"
     misc_feature    complement(13393..13404)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.58"
                     /tool="antismash"
     gene            13473..15089
                     /locus_tag="CHX35_RS09735"
                     /old_locus_tag="SAMN05444972_106176"
     CDS             13473..15089
                     /NRPS_PKS="Domain: AMP-binding (13-436). E-value: 2.3e-86.
                     Score: 281.8. Matches aSDomain:
                     nrpspksdomains_CHX35_RS09735_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007084251.1"
                     /locus_tag="CHX35_RS09735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106176"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_091836987.1"
                     /sec_met_domain="AMP-binding (E-value: 6.7e-102, bitscore:
                     334.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNVPLLISPMLERAERVFPKKEIVSCTPSGIHRQTYAQMGERTR
                     KLSDALQKLGVKQGDRVGTLAWNHYRHLEAYFAIPSMGAVLHTINLRLSPEHLAYVINH
                     AEDRILLIDDSLLPLIEAIREKLTTVEAFIIMSDQSELPKTTLSPLYSYEDLLSEGDPH
                     FEYPKDLDENSPAGMCYTSATTGMPKGVVYTQRSIYLHSMTAGLADTIGLSEGDTCLSV
                     VPMFHVNAWGLPFAATWFGAKQVLPGPMLKAEVLANLIQSEKVTVTGGIPTIWMELLKE
                     LEHKTYDLSSLRMLLFGGLSAPPSMIRAFEEKHGIPVVHAYGMTETSPIVTVSHLKSYQ
                     KDLPLEERLAIKAKQGLVSPGLEVRAIGSDGKEIAWDGKEMGELLIRGPWIADAYYKGD
                     RSSDAFQDGWLHTGDVVTIDEEGTIKVADRTKDLIKSGGEWISSVDLENGIMSHEGVYE
                     AAVVGMPHEKWQERPVACVVLKENYKNKVSEENIIDFLKPQVAKWWLPDEVIFMDELPK
                     STVGKFLKRALREQLEHRLSK"
     aSDomain        13512..14780
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHX35_RS09735_AMP-binding.1"
                     /evalue="2.30E-86"
                     /label="CHX35_RS09735_AMP-binding.1"
                     /locus_tag="CHX35_RS09735"
                     /protein_end="436"
                     /protein_start="13"
                     /score="281.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RAERVFPKKEIVSCTPSGIHRQTYAQMGERTRKLSDALQKLGVKQ
                     GDRVGTLAWNHYRHLEAYFAIPSMGAVLHTINLRLSPEHLAYVINHAEDRILLIDDSLL
                     PLIEAIREKLTTVEAFIIMSDQSELPKTTLSPLYSYEDLLSEGDPHFEYPKDLDENSPA
                     GMCYTSATTGMPKGVVYTQRSIYLHSMTAGLADTIGLSEGDTCLSVVPMFHVNAWGLPF
                     AATWFGAKQVLPGPMLKAEVLANLIQSEKVTVTGGIPTIWMELLKELEHKTYDLSSLRM
                     LLFGGLSAPPSMIRAFEEKHGIPVVHAYGMTETSPIVTVSHLKSYQKDLPLEERLAIKA
                     KQGLVSPGLEVRAIGSDGKEIAWDGKEMGELLIRGPWIADAYYKGDRSSDAFQDGWLHT
                     GDVVTIDEEGTIKVADRTKDLIKS"
     CDS_motif       14004..14054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHX35_RS09735_0001"
                     /evalue="7.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="CHX35_RS09735"
                     /protein_end="194"
                     /protein_start="177"
                     /score="15.6"
                     /tool="antismash"
                     /translation="MCYTSATTGMPKGVVYT"
     CDS_motif       14430..14477
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHX35_RS09735_0002"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="CHX35_RS09735"
                     /protein_end="335"
                     /protein_start="319"
                     /score="-3.0"
                     /tool="antismash"
                     /translation="HAYGMTETSPIVTVSH"
     misc_feature    15148..15157
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(15148..15162)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.73"
                     /tool="antismash"
     misc_feature    15149..15162
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.56"
                     /tool="antismash"
     misc_feature    complement(15186..15201)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.45"
                     /tool="antismash"
     gene            15187..16134
                     /gene="corA"
                     /locus_tag="CHX35_RS09740"
                     /old_locus_tag="SAMN05444972_106177"
     CDS             15187..16134
                     /GO_function="GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="corA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016766616.1"
                     /locus_tag="CHX35_RS09740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106177"
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="WP_091836989.1"
                     /transl_table=11
                     /translation="MVYTYAVTQDGEALHDIQLSQLKEDHIQWYWVDFAKPSADETQLL
                     ADFFDFHPLAIEDCLHRLQRPKMDYYHDHVFLIVHDVHPDTLEPEEVNLFVGENFIVTF
                     HLHGSEELAETRARVWREKDPSVLNPSVIAHRIMDKIVDTLFPVIHKIEDRLDELDSRQ
                     EVSTPELIDEVFDIRSELIRLRHSVIPMRDLLYRIINSRRFMQNDERRFYFSDIHDHLV
                     KLAHMIDSNREMTADIRDSYLSLNSFRMNRIMKTLTVITVIFMPLTFLAGVYGMNFVYM
                     PELHNREGYFIVLGVMVLLALSLTLWFKSKGWFN"
     gene            complement(16201..17433)
                     /locus_tag="CHX35_RS09745"
                     /old_locus_tag="SAMN05444972_106178"
     CDS             complement(16201..17433)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="CHX35_RS09745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106178"
                     /product="MFS transporter"
                     /protein_id="WP_091836991.1"
                     /transl_table=11
                     /translation="MNKFPPPFYALWIGQGIANLADSLYTIAMVTMLYTMSGSATMAAS
                     FPLVRMGAMMLGGFIAPLLFERWRLHRILLVSQLGQTMLLAILAIMTSGKLHPLYSLLL
                     VLCISFLDGWTTPTRNALLPQLIPSDLLMRGNSWLATTDQTVMLLGWASGGLLVTWMGS
                     DTLLWGCVILFSISCLALAPVRVPKSPSIDATTTPSRWQTLKQGWLMILHNPSLRRITW
                     MDAIETVASSIWVGAIMLVFVKEVLHRGSIWWSWMNTSYLLGTVLGGVLILALSRLLAH
                     RLAIGMLIGSTCNSFLVLLFALVPYPFVSLALCVLMGPCYQLRDITQQTLFQQAIPADV
                     LPKAFSAHGTLMYGIFGLGVVINGAIADHFGARSVYLVASVLLISSVLIGAPMLKNQPS
                     SAKTRSSITNL"
     misc_feature    17500..17514
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     gene            17627..18175
                     /locus_tag="CHX35_RS09750"
                     /old_locus_tag="SAMN05444972_106179"
     CDS             17627..18175
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003251319.1"
                     /locus_tag="CHX35_RS09750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106179"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_091836993.1"
                     /transl_table=11
                     /translation="MMAKILILTGDAVEALEVFYPYYRLLEEGHEAVIASPTKKKLQTV
                     VHDFEPHLDTFTEKQAYGLESHLSFDEINPTDYDGLIIPGGRAPEHIRMHGKLPDIVRH
                     FFTTNKPVGAICHATLVFNVVPDVLKGRSLTAFSNCRPEVEATGARYVEETLHTDGNLV
                     SGHAWPDLPGFMREFLRLL"
     gene            18322..18477
                     /locus_tag="CHX35_RS17550"
                     /old_locus_tag="SAMN05444972_106180"
     CDS             18322..18477
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS17550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444972_106180"
                     /product="hypothetical protein"
                     /protein_id="WP_176392009.1"
                     /transl_table=11
                     /translation="MTKAETSGGYFGYARGGWYPGLWIAIAVIVILLIFFACFWWWSAL
                     GGGPYY"
     gene            18537..18905
                     /locus_tag="CHX35_RS09755"
                     /old_locus_tag="SAMN05444972_106181"
     CDS             18537..18905
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012241.4"
                     /locus_tag="CHX35_RS09755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106181"
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="WP_091836995.1"
                     /transl_table=11
                     /translation="MLRPWLTKGPENWLGEIFNQMEQLSLQLEHNRIRGDLYQKNGKVV
                     VMMEIPGLQDRHEIDVRVEDQILIVRGTTGSGSSTTTSVEESSFIYEMLLPTKVEVSKM
                     ETVINPTERLLTIRLPVL"
     misc_feature    complement(18984..18998)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.25"
                     /tool="antismash"
     gene            19098..20186
                     /locus_tag="CHX35_RS09760"
                     /old_locus_tag="SAMN05444972_106182"
     CDS             19098..20186
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M42"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229495.1"
                     /locus_tag="CHX35_RS09760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106182"
                     /product="M42 family metallopeptidase"
                     /protein_id="WP_245838731.1"
                     /sec_met_domain="Peptidase_M42 (E-value: 2.2e-102,
                     bitscore: 335.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKSWSRLKQSLAELANVAGPPGHERATREVMERQMAPFADEISQ
                     DHLGSVIARQGSEGPRIMIAGHLDEVGFMVTRITREGYLHFRALGGWWSPVVTAQRVEV
                     MTKKGKVLGVVGSKPPHLMSLEQRKKVTPLDDLFIDIGASSEEEVESWGVQLGDVVVPY
                     SPFTEMNNPKYWLAKAMDNRLGCAVTVEVLRRLESIDHPNAVFGVGTVMEEIGRRGAYT
                     ATAVVKPDIGFAVDVGIASTPGCTPDEASSHMGDGPTLVLYDAGHIPHRGLLRLIQETA
                     KEKGIPLQYEWINGGATDASRIHLHGEGVPTVSLGVPARYIHSHTSLVHEDDTEQLVDL
                     LVAVVQKLDQNMVDQLADGTYT"
     gene            complement(20261..20497)
                     /gene="sspI"
                     /locus_tag="CHX35_RS09765"
                     /old_locus_tag="SAMN05444972_106183"
     CDS             complement(20261..20497)
                     /codon_start=1
                     /gene="sspI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012095709.1"
                     /locus_tag="CHX35_RS09765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106183"
                     /product="small acid-soluble spore protein SspI"
                     /protein_id="WP_091836998.1"
                     /transl_table=11
                     /translation="MNFPIRGAVYHNIKDMEASELRDMVLDSIKSGDEKLLPGLGVLFE
                     VIWKNSDASEQERLINTLHEHMPRDKAQPPVAQ"
     gene            20810..21601
                     /locus_tag="CHX35_RS09770"
                     /old_locus_tag="SAMN05444972_106184"
     CDS             20810..21601
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012797.4"
                     /locus_tag="CHX35_RS09770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106184"
                     /product="RNA methyltransferase"
                     /protein_id="WP_091837000.1"
                     /transl_table=11
                     /translation="MEIRKISSARNDRVKHWRKLSTRKGRDEYGSLLIEGIHLLEEAVR
                     AGWSVRSVIIPEEGTEILNRLPKLEGVPVYSLLDSTFRQVVETQAPQGVAAEVGMALER
                     GPFQPEANNRVLLLDAIQDPGNLGAILRTAEAAGVRDVWLGSGTVDPYNPKVVRSAMGS
                     LFRTRIRRVDLKKAIPDLQELGYTVIGTSPRANKSHFAFDYPDRVAILLGNEGKGISPV
                     IGALADTNVRIPMPGEVESLNVSVTAGILLYELVRQSEDSP"
     misc_binding    21659..21904
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            21955..22989
                     /gene="pheS"
                     /locus_tag="CHX35_RS09775"
                     /old_locus_tag="SAMN05444972_106185"
     CDS             21955..22989
                     /EC_number="6.1.1.20"
                     /GO_component="GO:0009328 - phenylalanine-tRNA ligase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pheS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015864754.1"
                     /locus_tag="CHX35_RS09775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_106185"
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="WP_091837001.1"
                     /transl_table=11
                     /translation="MRERLEALRKEAEVAIQAADDLEQLRDLRVQYLGKKGELTAVLRG
                     MKDVSAEDRPVIGGLANEIRSQIENLLAEKETAEREAALEKRLAAEAIDVTLAARPQPL
                     GGMHPITAVVEQIEDIFTGMGFVVAEGPEVETDRYNFEALNLPQDHPARDMQDSFYITP
                     EILLRTHTSPVQVRTMEEKEGQVPVKIICPGKVYRRDDDDATHSHQFYQVEGLVVDRGI
                     AMSELHGILAAFAEKMFGMALETRLRPSYFPFTEPSVEMDISCIKCSGKGCRMCKQTGW
                     IEILGAGMVHPRVLEGAGYDSERYTGFAFGMGPDRIALLKYGIDDIRHLYTNDLKFLRQ
                     FQSV"
     misc_feature    complement(23586..23604)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.67"
                     /tool="antismash"
     misc_feature    complement(24047..24056)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.24"
                     /tool="antismash"
     misc_feature    24244..24257
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.42"
                     /tool="antismash"
ORIGIN
        1 tggggaggta aacccgtcca ccctgttggt cgcagctggt ggtggcggcg ggggtggtgg
       61 attgaataca tcaagtgaag taggcggaga tgggatgaca acgagtagtg gtcaggacgg
      121 tgggaatgca gccggtggat ttggtgctgg ggggatggat gggaatagtg ggtccggtgg
      181 gaattttgaa atgggtttgg ctacgggagg tggagccgga ggcggtggaa gtccttactt
      241 taacggagga gatggggcgg ggaacgctgg tggaattggg ggagtgagta tcgtagcagg
      301 tggagccgga ggagcgggag gaaccggtgg cggtgagttt acaggtggag ccggaggatt
      361 tggcggaggt ggcggtggga gtgatcggaa tggcgggggt ggcggtggat ttagtggagg
      421 cggaggcggc acaggaacta gtaatgctat gggaggtgga agcgctggag gcggaggagg
      481 cggcggctcc tttaatgggg gatccaatcc agtgaatatg gcgggggtac gtgcggggaa
      541 tgggattgtg gaggtcacct atgaagcgcc aactcttacc tgctccaata tgaccgtcgc
      601 caatgatcgt ggcgcctgtg gagccaacgt tacctttagc gggcttggga cgtgtcccgg
      661 gctcatgatc gattgttccc ctgcctcagg ttctttcttt tccgtaggga ctacgagcgt
      721 gacgtgtacg gcaatggata ccgtgggagg gagtgctacc tgtagcttta ctgtcactgt
      781 catcgataca gaacctccag tcatttccgg gctccacgat atcgatgtgg aaacgaacaa
      841 tcccaatggt acggtcgtta cctatcccga tcccacggtg acggacaatt gtccgggaga
      901 gatcaccgtc acctgttccc ctgcctcagg ttctttcttc cccttaggaa tgacgatggt
      961 tacttgtact gcgacggatc caagcggcaa tacggcaacg ggcaccttta ttgtcgtggt
     1021 tacttcgtcc caagaggagt aagaaatcgt ttttcagcga agaattaacc agaacaccat
     1081 ccgattgtag gtacaggtca aaggaaggtg aaaaactttc atagaaagca gaatgatcgc
     1141 aatatcgatt ttatttatta gcaatcttaa ataataaagc tgtttagaga gtcgatatca
     1201 aactaaacag ctttttttat gtgctatgac gttcatccga tgaatatctg caacatacat
     1261 aaagagataa gagtttgaaa aggagggcgt gttatgcccg catttacata tacaggagca
     1321 ttgcagacgc taacaatccc aggaggggtc tgtcgtgtga cgattcaggc ccaaggtgct
     1381 gcagggggaa gtaatctatt ttatagttcc tttgatgagg atggaggcgg gctaggtgca
     1441 tcgattcaag ggacgtttgc ggttgcacct ggtgatgtgt tatcgattgt cgttggcggg
     1501 caagggggcg acacaccgga tattaatgaa ccgaatggtg ggggtggagg cggaggtggt
     1561 tccttcgttt ggcaaggcag tagttttggg gagttaaatc cgtctacctt attagtagcg
     1621 gcagggggtg gaggcggggg tgcgggattt gactttggtg aagatgacag tgggagtgct
     1681 tctggtggaa gtgggatgat tgggagtatc gggcaggatg gggggaatgc agccggtgga
     1741 tttggtgcag gggggactgc tgggaacggt gggtcaggtg gaaatggcgg gatgatggcg
     1801 gggttgggcg gaggaggcgg aggcggaggc ggaataaatt ttaacggagg aaatggtttt
     1861 gggaacgcag gcggtgatgg gggagtgagc attgttgcgg gtggagctgg cggtgcaggg
     1921 ggtgtgggtg ccatgggtga ctatatcgga ggcgatggag gatttggtgg cggcgggggt
     1981 gggagtgatc ggaatggagg aggcggaggt gggtttagtg gcggtggtgg cggtacgggt
     2041 gttggttttt ttgtagcggc tggaggaggc ggaggcggag gttcctttaa tgggggcact
     2101 aatccggtcc atatggaggg agtacgcgcg gggaatggca ttgtagagat tatttatgaa
     2161 gcgccgaccc ttacctgctc gaacattacg gtcgccaatg atcgtggcgc ctgtggagcc
     2221 aacgttacct ataacgagct tgaaacatgc cccggactcg acgtcacttg ctctcctgcc
     2281 tcgggttcct tcttttccgt gggtacaacg acggtgacgt gtaccgcgat ggataccgtg
     2341 ggagggagca ctacctgtcg ttttatcgtt acggttattg atacggagcc ccctgagatc
     2401 tccggactta acgatatcga tgtcgaaacg aatgatccca atggtacggt cgtcacctac
     2461 cccgatccca tagtgacgga taactgtccg ggagagatca ccgtcacctg ttcccctgcc
     2521 tcgggttcct ttttcccctt cgggatgacg acggttactt gtactgcgac agatccgagt
     2581 ggcaacacgg caaccgagac gtttacggtg tttgtgacct catctcaaga agagtaatgg
     2641 atttttttgc aaacggtatc gatcaattac accctcgtga agatccccta catgatgaat
     2701 gtaggggatc tttatggaga aaaaaggtaa tgaaatatgg ttttgattct tcactgaaga
     2761 ttgaaataag gccttctttc aatttgaaaa ggagggattt tacgaaattg ggggatatta
     2821 atagggacaa gggtgtttga gggggcgtgt agggtcattg attaataaga aaaatttatc
     2881 cttgatggta tggctcatcg tgcttgtact gggtgcctgc acgttcctat tcatggatcg
     2941 agggcaattc aacccagaga ccattcgata tgtggtgctt tcatatggtg tttgggcacc
     3001 gattctctat ttgttgatgc atatcgttcg gcctttattc ttggtgcctg ccacggtact
     3061 agcggttgcc tcagggatta cttttggacc ctggtggggg actttgttgg atgcaagtgg
     3121 ttctcttgct ggagcgatgg tagctttttc gcttgcccgc tggttaggca aggagacagt
     3181 gagtcgatgg ctaaatcaat ttacgcattg ggaacgatgg atggtggatg aagggtttcg
     3241 tacgattgtg atttctcgtt taatcccctt tcttcccttt gatgcgatta gctatggtgc
     3301 agggttctcc aatatcaagg tgaacgatta tttttgggcg acagtgattg ggattctccc
     3361 tggggccttt gtgtttaatg tgctagggta ttcgcttcat gatctgttct ctccgttgtt
     3421 ctttgcctca ctgggagcag ctcttgtact cgccatctca ccctggttgt ttcgacgact
     3481 tcgtcgtaat tatgtgaaac aaaagtaaga aagtgacccg ggaaaataga tcactttctc
     3541 tttcatgatg acggtttatg tacaatgctt aatcaattaa tttttggaga aggtgcaaca
     3601 gtgaatcaag ctcctcatcg gatagtgtat gaaagagctg ttggaaatac tggaaccgac
     3661 gttttaccat ttcattgtaa acctcggttc cagctggggt aatcgcaagt tctacaattc
     3721 gtttgtcatc agtggagcgg tgacgactga tccaaccttt tttcaccatg cgattcacat
     3781 gttgcgtaac atggctgttg gttacgttta gttcgctaga aagatcggaa cctttgctag
     3841 ggccctgtgt atgtaattga tgcaaaaata caaaatcagc gactccccag ttctcttcca
     3901 gttgttgttg aatgccgcga cgaagtttat gaacgacatg ttgaaaggct tgaatagtat
     3961 catgggtcat ttgtgtacga tcagacaagg tgatccttcc tctcgagtaa ctaatagtta
     4021 atattgttaa gtatatgcca tttgcattct acagtgcgga aacttttttg tcaatcaatg
     4081 ggtatgaaaa tgttgccaat gagaaagcat ccactgagcc gagaagaaga attcttccat
     4141 gcagatccag ctttttagat ccaatcaggg aaaaaaatcg tgacttctgt cagggaatcg
     4201 attaaactgg tctgaaaaat gttgaccgat gacaaggagg taacaacaat tgagcaccaa
     4261 tgagacaaaa gatctgcgga ttcgaagcca tgtcatcagc gaaggggcaa accgcgtacc
     4321 gaatcgggcg atgcttagag cgacaggctt tacggacgaa gattttcaaa aaccgatgat
     4381 tggtgttgca agtacctggt ctgaagtaac gccgtgtaat atgcacatta aagagttggc
     4441 agaagaggcg aaacgaggcg cagtggaagc gggtggggct ccgatgattt ttaataccat
     4501 taccgtttcc gatggcattt ccatgggaca cgagggaatg cattattccc tacctagccg
     4561 tgaagtgatt gccgattcga tcgaaacggt gattggtgct gagcgattgg atgcctatgt
     4621 agcgattggc ggttgtgata aaaacatgcc agggtgcatg atcgcaatcg gacgtaccga
     4681 tgttcctgca gtttttgtct atggcgggac gattcgacca ggaaaactgg acggaaaaga
     4741 tattgacatt gtctctgcct ttgaaggggt gggccagtat aaccaaggaa caatcgatcg
     4801 ggaaggcttg cacgagattg agtgtcatgc ctgtccagga gcaggttctt gtggtgggat
     4861 gtataccgcc aataccatgt cctcagcgat tgaagcctta gggatgagtc tgccaggaag
     4921 ttcctctaat cccgctgaaa ccaaggagaa attagcggat tgtcgggagg ctggagcagc
     4981 agctgtcgaa ctattgcgta aaggaatcta tcccaaggat attatgacga aagaagcatt
     5041 tgaaaatgcc attactgtgg tgatggcgtt gggagggtcc accaatgcca ttctgcattt
     5101 actggcaatg gcccattcgg tggatgtgga tctaaccatg gatgattttg aacgagtgag
     5161 ggaacgggtg ccccatatcg cagatttaaa accttcgggt cgatttgtta tgcaggatct
     5221 gtatgaagct ggaggtgtgc cagcagtgat gaaagtcttg ttagaacaag gtcttcttca
     5281 tggtgattgc cttacggtga cgggtaaaac gataaaagaa aatttggcgg aggcagagcc
     5341 ccttcgcgcg ggacaagaag taatacgccc ttttgacaaa ccattccgaa aaactggtcc
     5401 actggtggtt ttagaaggga atctcgcacc tgaaggggca gttgcgaagg tgtcgggcct
     5461 caaggtgaat cagttgactg gtcctgcgcg tgtttttgat tccgaagagg cagcgacagc
     5521 agccatcctt tctgatcaga ttaaggtagg cgatgtggtc attatccgct acgagggacc
     5581 caaagggggg ccagggatgc cggaaatgct ctccatcaca ggaatgttgg tcggaaaggg
     5641 actaggtgag aaggtagccc tgttgacaga tggtcgattt tcggggggtt ctcatgggtt
     5701 ggtcattgga catattgccc cagaagccca agtagggggt ccaatcgcac tggtagaaga
     5761 tggtgatcag gtaaccattg attcggtaaa gcgagaatta tccgtagcgc tttctcctga
     5821 ggagctaagc cgtcgccgct ctgcgtggca agaacggccc cttcctgtac gccgtggtgt
     5881 ccttcataag tacagtaaac tcgtctcttc tgcctcaaag ggagctgtca ccgattgatc
     5941 aaaatttatt ttgagagact ggttgacaaa ggtagaagca cctgcctata atagcaccta
     6001 aataattcaa gaatttagcg atgagatgca tgaaagcaac tccgtgtatg atgggagggt
     6061 acctagggtt ccgctcgctt tgcgaggtct gtgaccgagt ggtaccaaca ccaactggtg
     6121 tacaccgtga ggataaaagc ctctgcggaa ggtcctacct tgattgaggt tgaaaggtat
     6181 ggattttccc caggggcttc ttgtatgccc taggaaactg aaaataatta agattcaatg
     6241 gattatgtga atgcgatgaa gaggccatac cctttggaaa atcctatcac agagagtcct
     6301 ggaaatgctg aaaccaggac agtggaccca aaggcgtgct cacctcggag ctgtgcgtcg
     6361 aaaggtggga aaccccttag tagaacgtta ccggatgatc gccgttaccg atcagggtat
     6421 ttcaaagttg gaatacctgc cgagtctgtt cgccgcgagg cgacagagat attgggtggt
     6481 accgcgaacc cttcgcccca atcaactgta acagcgttag actgtctatg gttggtgggc
     6541 gaagggtttt attattttac aattaggggg ttgaacctgg atgggccata cagtgacaat
     6601 ggttggcagt cagtcaggaa aggcggaatc acccaaaaca gagtatacgg gctccgaaat
     6661 tttacttcgg tgcttgattg aagagcaggt tgatgtcgta tttggctatc caggaggcgc
     6721 tgttcttcca atctatgatt cgctctatga agggggtttg cggcatcttt tggctcgtca
     6781 tgaacaagga gccattcacg ctgctgatgg atatgcaagg gcgacgggga aaccgggtgt
     6841 ggtgatagcg acatcgggtc caggtgcgac gaatctagtc acgggaattg cgacggctca
     6901 gatggattcg attcccatgg tctgtatcac ggggaatgta tcccaggaat tgatgggtac
     6961 ggatgctttt caagaggcag acattatggg aattaccatg cccatcgtca aacatagcta
     7021 cttggttacg gatgtatgtg accttcctcg catcgtcaag gaagccttcc atcttgcaag
     7081 tacagggcga cccggtccgg ttctcatcga tattcccaag gatgtggcta atgcaagaga
     7141 cacctttcac tatccaaagg gcgtctccat tcgtggctat cagccaacat caagtgccca
     7201 ccccttgcag ttagcacggc ttcgagaagt gattgcagaa gcaaaaaggc cagtgatcct
     7261 tgcaggtggt ggggtggtga cagcaggtgc ggaaaaggaa ttgatcacct ttgccgaaca
     7321 aacgcaaatt cctgtcatta cgaccttgat ggggctaggg ggatttcccg ggcaacatcc
     7381 tttgtggttg gggatgccgg ggatgcatgg aacctatgca gcgaaccatg cactcttgga
     7441 aaccgacctc ttgattggaa tcggagctcg ctttgatgat cgggtcacca tggggcgtct
     7501 tgataaattt gcaacaaagg cgaaaattgt gcacatggat atcgatcccg ctgagattgg
     7561 aaaaaacgtc aacacattta ttcccatcgt cggggatgtg aaaaatgttt tacaggcggc
     7621 caatgtcgat ttaccacaaa gtgactcagc cgcctggatt gaaaaagtga cgggctggcg
     7681 agagtcttac ccgctttgct atcgggattc cgaagaccgg ttaaagcccc aatgggtcat
     7741 acgccatctc tatgaaacaa caggcgggga tgccgttgta acgacggatg tgggacagca
     7801 tcagatgtgg gtggcacaat atttccactt tgcacgtccg cgttctttta tctcatcggg
     7861 aggactcggt acgatggggt ttggctttcc cgccgccctg ggtgcacaac tcgctacacc
     7921 agaacagctg gtgatcagtg ttaccgggga tggcggtttt caaatgacca atcaagaatt
     7981 ggctgtagct agcttggcca atattccggt gaaagttgtc attatcaaca atcaaaatct
     8041 tggcatggta cgccaatggc aagaggtttt ttaccataaa cggtacagtg aagtggatct
     8101 atcggggagt cccgatttcg tgaaattgac cgaagcatac ggagtgaagg cttggcgcgc
     8161 aaaaacgaag gaagaggcaa ttaccgcatg ggcggaggcg ttggcccatc cgggtcccgc
     8221 agttgttgat ttttgggtgg cccctgatga aaatgtctat ccgatggtcg ctccagggaa
     8281 agggctcgat gaaatgatca tgggagatga aaaagcgtga gacatgtcct atcagttcta
     8341 gtcaatgatc aaccccgtgt actggctcgg gtatccacac tattggggcg tcgtaatttc
     8401 aatattgaga gtattagtgt gggagaatct gaagaaaaag ggttgtcacg gatggtgatc
     8461 gtgactcacg gggatgaacg aacgatggag caggtgcaaa aacaacttca caagttgatt
     8521 gatgtgatta aagtgcatga tttgtcgaat catcctgcag ttgagcgaga gctcctcttg
     8581 attaaggtgg aagctggacc cgcggcgcgt atggagatat cgggagtggt tgagcccttt
     8641 cgtgcggcag tggtcgatgt aggctcgcag aatatgatgg tgcaggccac gggggaacgg
     8701 gcgaaattag atgcattgat tgagttactt cgcccctatg gaattaaaga gatcgctcgg
     8761 accggcgtga ccgccctctc acgaagcatg gtgcagggaa acagttaaaa agatgatgca
     8821 aggaacttcg atgaaaaata tccacttata gggggaatgg aacatggcaa cagtctatta
     8881 cgcaaaggac gcagatctca agcaattagc aggtaagacg gtagcgatca tcgggtatgg
     8941 tagccaaggt catgcacaag cacaaaacct acgggatagt ggtgtgcaag ttgtaatcgg
     9001 attacgcaaa gggaagtcct gggagaaagc tgaaaaggat ggatttatag tattggaagt
     9061 agctgaagct gtgaaaagat ccgaggtaat caaccttttg atgccagatg aaacgatggc
     9121 acaggtgtat aaagaagaag ttgaaccgaa tctaaagccc gaagcggctc tcctattctc
     9181 ccatggattt aatattcatt ttaatcagat ccagccacct cctcatatcg atgttgcctt
     9241 aattgcaccc aaaggacccg gtcacttagt acggcgggtc tatacagaag ggtttggcgt
     9301 cccagggttg attgctattc atcaagatgc gagtggatct gcaaaagcga ttggtttagc
     9361 ctatgccgag gggattgggg caacgcgtgc cggtgtgatt gaaacgacat ttaaagaaga
     9421 aaccgaaacg gatttgtttg gtgagcaagc ggtactttgt ggtggggcga gtgaactcgt
     9481 gaaaaaaggg tttgaaaccc taacggaagc agggtatcaa ccagaaattg cgtattttga
     9541 atgtcttcat gaactgaagt tgatcgtgga cctcatgtat gaggaagggc ttgcaggaat
     9601 gcggtattcc attagtgaca cggcggagta cggggattat gtcagtggga aacgtgtggt
     9661 tggcgatgct tccaaagcag caatgaagga agtgcttaag gaaattcaag atggtacctt
     9721 tgctcaacaa tggattaccg aaaataaaaa tggtcgtcaa gagtttacga ggattcggaa
     9781 agaagaaggg gagcacctgt tagaaaccac tggagaaaaa ctaagggaaa caatggcttg
     9841 gatcaatcaa aaacagagtg ttaaagcctg aacgacaaac tcttagcagg ctctcgcagt
     9901 ccctgggatg aaaacgaagg aggcttgact cgctcccaac ttgagcaggg tttcgtaact
     9961 tcggtaaaca gtttaacaaa aatcggaagg aggatgcggc atgagtagtc gaaccgtcca
    10021 attttttgat acgaccctac gcgatgggga gcaatcccct ggtgtgaacc tcaatgtaga
    10081 agagaaggtg gagatcgctc tacaacttga aaaattgggc attcaagtga ttgaagcagg
    10141 atttgccgcc tcctctgccg gcgatcgtga agcggtaagg agggttgggg aagcggttca
    10201 caccccgatt gttgtcagtc tggctcgcgc tgtggatgtc gatattgatg cggcttggga
    10261 tgcgttaaaa acggcaacaa acccaggggt ccatattttt ttagccacct cgcccattca
    10321 tcggcagtat aagctcaaca tgaccaagga ggagatttta aatcaggtgg aggcggctgt
    10381 ccgctatgca aagcgattct tcccccatgt tgaattttct ccagaggatg gcggacgtac
    10441 ggagctggat tttctgtgcc aagttgccga acgagtcatt gaagcgggtg cggatgtctt
    10501 aaatattcca gatacggtag gatacctttc tccccaggag tatgggaata tctttcggca
    10561 tttaaagtcc catgtaaatg gaatcgaaaa ggtaaaacta tcggcacact gtcatgatga
    10621 cttgggtatg gcgacagcta atacattggc agccattgaa gccggtgtgg aacaagtaga
    10681 ggggacaatc aatggcattg gtgaacgtgc tggaaacgct gcgcttgaag aggttgcaat
    10741 ggctttggcc acccgctcaa cctattatgg tgtgaagacg aatcttcaat tggcggaaat
    10801 tgctcgcacg agccggattg tctcgaagat gacggggatg tttgttccag gaaataaggc
    10861 ggttgtcggt gcgaatgcat ttgcccatga gtctgggatc catcaagatg gcatgttaaa
    10921 gcatgcatct acttatgaaa tcatgcgccc agagacggtg ggacaggcgg atacacggct
    10981 tgtattaggg aagcattctg gtcgccatgc tttccgcgat aaactggtgc aattgggtta
    11041 tgcctttaat gatcagcaga ttaatcatct ctttcaccgg tttaaagaac tgactgatcg
    11101 gaagaaattg attgaagatg atgatctggt ttcccttgtc gaagaacgga tcggtgacga
    11161 agaagaagtg tactcctttg aaacggtaca ggtagcttat ggtaatcaat ccgtgccaac
    11221 ggcatcgcta cgaattaaag ataaccgaga tcaacgccta ctcgaagaag cagcctgtgg
    11281 aaatggctcc gtcgatgcca tctttaaagc gatcgatcgc atcaccaatg aagcttggca
    11341 ccttgaggat tatcgcattg tgtccgtgac gcacggaaag gatgcgctgg gtgaggtata
    11401 cgtaaagctt tcggatggag aagagagcac ggttcaagga agaggggtat cgacggatgt
    11461 gttagaggca agtgcacgtg cctatataca tggggtcaat cgcttactcg ctcggcgaaa
    11521 tcgtgagaaa caacccgctg gagttggatc aataagtggg taatgaaggg gaaggagtga
    11581 tcaagatgac aagaccgaag cgtatcgcag tactacctgg agatggaatt ggtccggaaa
    11641 tcgtggaaga aggggtcaaa gtgatgaaag cggctggaga gcgcttcggt tatcactttg
    11701 agattgactt tggatggata ggcggttccg cgattgatcg cttgaaaaat ccattgccac
    11761 aagagacgtt aaccttgtgt catcaagcgg atgctgtatt gctcggtgct gttgggggac
    11821 ctcgttggga tcaacatcct cctgcattac gacctgaaaa agcccttctc ggattacgaa
    11881 aagagctgga tttgtttgct aatttacgac ctaccactct tttcccaggg ttagaggaca
    11941 gctctacctt aaagccggaa gtgctaaaag gcgttgattt tctggtggtg agagagttaa
    12001 ctggtgggat ttactttggt gaaaagttta ccgaagatac accggcagga gagaaggcaa
    12061 cggatacgtt agtttattcg gagacagagg tagaacgcat tctccgccgt gcctttgaca
    12121 ttgcgcaact tcgtggtaaa aaagtgacct ccgtcgataa agccaatgta cttgaaagtt
    12181 ctcgattgtg gcgaaaagtg gccgatcggg tagcgaagga ttacccggat gtcgaactga
    12241 cgcacctctt agtggataat tgtgcaatgc aaatgattcg tcgaccagca gactttgatg
    12301 tcgtcgttac tgaaaatatg tttggggata ttctgagtga tgaggcggcg attcttacgg
    12361 gctccatcgg tcttcttcct tctgcaagtc tgggtgaggg tcatcaaggg ttgtatgagc
    12421 cggtacatgg ttcagccccc gatatcgcag ggcaaggggt agctaatccg attgcaacga
    12481 tcctttccgt tgcactgatg ttccgctact cctttcatga tgacaccgtt gccaaggcga
    12541 ttgagggagc cgtaaccgat acccttgctt ctggagcgcg gacgatggat ctggtctcga
    12601 caggtagatt ggcttactcg acggaggaat tcggggataa ggtggtcgaa gcgcttaaca
    12661 agtatcaacc cgaccctact ctgccagtag aagcgatgat gtagtggatc cttgtaagat
    12721 ggataagtga gatgcaagac tgcggaaggt gtatggatgg gagatccgca gtcttttcat
    12781 ttcataaaaa agtggtttat aaatcatgaa ttaacggaat aataagaatt ataaacccaa
    12841 gtgatcggat agaaattggg agaaagggag atgctctgtg gcgataaatg aagggtggct
    12901 agctcacctc catgccttga atgctttgga aaggctgtat catgagtatt gggatttgga
    12961 tttagcggaa aaagtacgca gtgaattagc gcggagtgtg gatctgctcg gttcccatgt
    13021 agacaaagtg ccatgtcctt gtggggatac ccgtgaagat gtaacctttt atcgatcgct
    13081 cctccgacat gcggaagcat ctgtagcaga gcgaaatctt tttcctctac ccttggtaca
    13141 agaggcactg actcaccatt tcacccataa aagcgaaaaa catcgttgta tcgggcgact
    13201 aattgggcgg gagcatgatt gggtgaaagg gatggaaaca ggttgaggtg aatgattaaa
    13261 gaagaaaaag agggaggcga tgaatcctcc ttctttttct tctttataaa ggtcatccaa
    13321 ttggaaacaa attctatctt atgggatagc aatctatatt tttcaaggga ttgagtgtgg
    13381 atcactttct gcggaagcgt tttcaatata gtttgtatcg agtataatga agaatagaat
    13441 atactacaga tcaagagagg tgggaatggg cgatgatgaa tgtgcctttg ttgatttccc
    13501 ccatgttgga acgggcggaa cgcgtgtttc cgaaaaaaga gatcgtttcc tgtacccctt
    13561 cgggaattca ccggcaaact tatgcacaga tgggtgagcg gacacgaaag ctgtctgacg
    13621 cactgcaaaa actaggtgta aaacagggag atcgagtcgg taccttagcc tggaaccact
    13681 atcgccactt agaagcctat tttgcgattc catcgatggg agccgttctt cataccatca
    13741 atttgcgact ctctcctgaa catcttgcct atgtcattaa ccatgcagaa gatcggattt
    13801 tgttaattga cgatagctta cttccactta ttgaagccat tcgtgagaaa ttaaccaccg
    13861 tcgaagcctt cattattatg tcagatcaat cagaattgcc aaaaacaacc ttgtcgccac
    13921 tgtactcgta tgaagatctc ttatccgaag gggatcccca ttttgaatat ccaaaggacc
    13981 ttgacgagaa ttctcctgcg ggaatgtgct atacttccgc aaccaccggg atgcctaagg
    14041 gcgttgtcta cacgcaacgg agtatttacc tgcacagcat gacagcgggc ttagccgata
    14101 ccattggttt gtctgaggga gatacctgtc tatccgtggt acctatgttc catgtaaatg
    14161 cttgggggct tccctttgca gcgacgtggt ttggtgcaaa acaagtctta cccggtccga
    14221 tgctaaaagc agaggtactc gctaacttga ttcaatcgga gaaggttacc gtgactggtg
    14281 ggataccaac gatttggatg gaacttttga aagaattaga gcataagacc tatgatcttt
    14341 ctagtctccg gatgttgtta tttggcggat tatcggcgcc tcctagcatg attcgggcgt
    14401 ttgaagagaa acatggcatt ccagtggtac atgcttatgg catgaccgag acgagtccga
    14461 ttgtaacggt ctcccatttg aaaagctatc aaaaggattt gcccttagaa gaacgtttag
    14521 ccattaaagc caaacaaggg ttagtttccc cgggtctaga agttcgtgcc ataggctctg
    14581 atggaaaaga gattgcctgg gacggcaaag agatggggga gctactgatt cgtggtcctt
    14641 ggattgcgga tgcgtactat aaaggggatc gttcgagtga tgccttccaa gatgggtggc
    14701 tgcatacagg cgatgtggtg accattgatg aggaagggac gatcaaagtt gccgatcgaa
    14761 ccaaagattt gataaaaagt ggcggcgagt ggattagttc ggtggatctt gaaaatggga
    14821 ttatgtcaca cgaaggggta tatgaagcgg cggtggttgg gatgccccat gaaaagtggc
    14881 aggaacgacc cgttgcttgt gtcgtgttaa aagagaacta taaaaataag gtttcggaag
    14941 agaacattat cgattttttg aaaccacaag ttgcgaaatg gtggttacct gatgaagtga
    15001 tttttatgga tgaattgcct aaatccaccg ttgggaagtt tttgaaacgt gccttacggg
    15061 aacaactaga gcatcggctt tccaagtaaa gggcttcaac gtgaagcagg gagataaaac
    15121 aacgcccccg ataaaggggc gttgttttat tttttgaaaa agcgactcga ttacggaggg
    15181 gtttcgatgg tttataccta tgccgttact caggacgggg aagcacttca tgacatccaa
    15241 ttatcgcaat taaaagaaga ccacattcag tggtattggg tagactttgc caaaccatca
    15301 gcggatgaga cgcagttatt agcggacttt tttgattttc atcccctcgc gattgaggac
    15361 tgtcttcatc gacttcaacg gcctaaaatg gactattatc acgatcatgt ttttcttatc
    15421 gtccatgatg tacatccgga taccctagag ccagaggaag tgaatctttt tgtaggtgaa
    15481 aattttattg tcacttttca tctgcatggc tctgaagaac tagcagaaac tagggcacgt
    15541 gtatggaggg agaaggatcc ttcagtgcta aaccccagcg tgattgccca tcggattatg
    15601 gataagattg tggatacgtt atttcctgtg atccataaga ttgaagatcg cttggatgaa
    15661 ttggacagcc ggcaggaggt ctctacacct gaattaattg acgaggtatt tgatatacga
    15721 agtgaactga tccgccttcg tcacagcgta atcccgatgc gagatctttt gtatcgcatt
    15781 attaactcca ggcgatttat gcaaaacgat gaacgtcgtt tttattttag tgatattcat
    15841 gatcacttag tgaagctagc tcatatgatt gactccaatc gggagatgac ggcggatatt
    15901 cgtgatagtt acctatctct caactccttc cgaatgaacc ggatcatgaa aaccctaacg
    15961 gtcatcacgg tgatatttat gcccctcacc tttttagcag gggtttatgg catgaatttt
    16021 gtgtatatgc ccgagttaca caaccgagag ggatatttta ttgttcttgg cgtcatggta
    16081 ctgcttgcct taagtctgac gctctggttt aaaagtaaag gttggtttaa ttaaggtttc
    16141 cttacgctaa aaggccccac acacctgtaa tgacggtgat gtggggcctt ttcaatacga
    16201 ttacaaattc gttatggagg atcttgtttt tgcgctactc ggttgattct tcaacatagg
    16261 agctccgatt aagaccgagc tgatcaataa aacagaggcg accaggtaga cggatcgggc
    16321 gccaaagtga tccgcgatgg caccgttgat tacgacaccg aggccaaata ttccatacat
    16381 caaggtccca tgagcggaaa aggccttagg gagaacatca gcaggaatcg cttgttgaaa
    16441 aagcgtttgt tgtgttatat cacgcaattg gtaacaggga cccatcaaga cgcaaagcgc
    16501 aagggatacg aacggatagg ggacgagggc gaataagagt actaaaaagc tattgcacgt
    16561 cgaaccgata agcatcccaa tggcgagtcg gtgagccaat agacgcgaaa gggcaaggat
    16621 tagtacgcct cccaatactg tgcccagtaa ataactggtg ttcatccacg accaccagat
    16681 ggatccgcga tggagaacct ctttgacaaa gaccaacatg attgcaccga cccagatcga
    16741 gctggcgact gtctcaatcg catccatcca ggtaattcga cgtaggctgg gattgtgtag
    16801 gatcatcaac caaccttgtt tcagggtctg ccagcgcgaa ggggttgttg tcgcatcaat
    16861 cgatggactt ttcggaacac gcacgggtgc tagggcaagg caggaaatcg agaagaggat
    16921 gacacacccc cataaaaggg tgtcgcttcc catccatgtg acaaggagac cgccgctggc
    16981 ccatcccaaa agcatgacgg tttgatccgt ggttgccagc cagctatttc cccgcataag
    17041 caagtccgat ggaatcagct ggggtaataa ggcgtttctt gtcggtgtgg tccatccatc
    17101 taaaaaggag atacataaaa cgagcaacag actatagagt gggtgtaact ttccacttgt
    17161 catgattgca agaatagcaa ggagcatggt ttgccccaat tgggagacca atagaatccg
    17221 gtgtaatcgc catcgttcaa ataaaagggg agcaatgaat cctcctagca tcatcgctcc
    17281 catccggaca aggggaaagg atgcggccat ggtcgcagaa ccgctcatcg tgtataacat
    17341 cgtcaccatg gcaatcgtgt ataaggaatc cgcaagatta gcgattcctt gaccgatcca
    17401 gagtgcataa aacgggggtg ggaacttgtt catcgttgct ctcctattga tcgcagtatt
    17461 tgattgtatg aggtttttat atatcagcga ttaataggga tcacacgggt cgattccgcc
    17521 ctttcatgca aggtatcctt actgtaacac aaattttttg gcgaagagag gtttaatgat
    17581 tttcatatca ggaaaaatat catacaaact tgtgcgggag ggtgttatga tggcgaagat
    17641 tttaatctta acgggggatg ctgttgaggc gttggaggta ttctacccat actatcgctt
    17701 gcttgaagaa ggacatgaag ccgtgattgc ttcaccaaca aagaaaaaat tacaaaccgt
    17761 ggttcatgat tttgaacctc acctcgatac ctttacagaa aaacaagcct atggcttaga
    17821 gagccatctc tccttcgatg aaattaaccc aacggattac gatggattga ttatacctgg
    17881 ggggcgtgct ccagagcata ttcggatgca tggaaaattg ccagatatcg tgcggcattt
    17941 ttttacgaca aataagccag taggagccat ctgtcatgcg acgttagtgt ttaatgtcgt
    18001 tcccgatgta ttgaaaggac ggtccctcac ggccttttca aattgtcgcc cggaagtaga
    18061 ggcaactgga gcgcgatacg ttgaggaaac tcttcacacc gatgggaatt tggtttcagg
    18121 tcacgcttgg cctgatctac ctgggtttat gagggagttc ctacgcctcc tataaatcat
    18181 taaagagtgg gggatacaga aaaacgctcg cgatttgcgg gcgttttttc atgggaatta
    18241 gggcatttat ccataccgga atggttcttt atacataccc tataccgagc gcctgtgtgg
    18301 ggggagagga ggtggaagtc gatgactaaa gcagaaacca gcggtggtta ttttggttat
    18361 gccagaggag ggtggtaccc tggcctctgg attgcaattg cagtaatcgt catcctcttg
    18421 atcttcttcg catgcttctg gtggtggagt gccttgggtg gcggtccata ttattaaatc
    18481 attgctagtg gaagcccctt aacggtggga ttcactggtg ggaaaggagg atcgggatgt
    18541 tacggccatg gttaacaaag ggtcccgaga attggttggg agagattttt aaccaaatgg
    18601 aacaactctc ccttcagtta gaacacaatc gaatacgggg agatctctac cagaaaaatg
    18661 ggaaggtcgt tgtgatgatg gagattccag ggctgcagga ccgacatgaa atcgatgtgc
    18721 gtgtggaaga ccagatcctg atcgttcgag gaaccacagg gtcgggttca tcgacaacaa
    18781 catcagtgga ggaatccagt tttatctatg agatgcttct cccaacaaaa gtcgaagtat
    18841 ccaagatgga aacggttatc aatcccactg agcgcttgtt gacgatccgc cttccagtcc
    18901 tgtgaatgga acaccgtcaa ggtttaatta agtaaagccc ggaactaacc gggctttact
    18961 tatgtgttga tggtttgcat ccattcgtaa attgtgaatg aggaataagg agtggcgctt
    19021 atgataagat agcaagagtg aacaattagc acttaaaacc ggaatggttt tgtggttagg
    19081 aagaggtgga tggaatggtg gaaaaatcat ggagtaggtt gaaacaatcc ttagcagaat
    19141 tggcgaatgt tgctggcccc cccgggcatg aaagagccac cagggaagtg atggagcggc
    19201 agatggcccc ctttgcggat gaaatttctc aggatcattt gggaagtgtg attgcacggc
    19261 aaggaagtga gggtcctcgc atcatgatcg ccggtcacct ggatgaagtc ggctttatgg
    19321 tgacacgaat tactcgtgaa gggtaccttc actttcgagc attaggtggt tggtggagtc
    19381 ctgtcgtcac cgcgcaacgg gtagaagtga tgacgaaaaa ggggaaagtg ctaggggtcg
    19441 tgggttctaa acctccacac ttgatgtctt tggaacaacg gaaaaaggta acgccgttgg
    19501 atgatctttt tattgatatt ggggcatcca gtgaagaaga agtggaatcc tggggagtac
    19561 aactgggtga tgtagtggta ccctattcac catttaccga gatgaacaat ccgaagtatt
    19621 ggttagccaa agccatggat aatcggttag gttgtgcagt aacagtggaa gttcttcgtc
    19681 gcctagaatc gatcgatcat cccaatgctg tttttggagt ggggactgtg atggaagaaa
    19741 tcggtcgcag gggcgcctat acggctactg cagttgtaaa acccgatatc gggtttgctg
    19801 tggatgtagg gattgcctcc acaccaggtt gtactccaga tgaagcctcg agtcatatgg
    19861 gggatggccc cacattagtg ctttatgatg cggggcatat tcctcatcga gggcttcttc
    19921 gcttgattca agaaacagca aaggaaaagg gtattccgct tcaatatgaa tggattaatg
    19981 gtggggcgac tgatgcgagt cgcattcatt tacatgggga aggtgtaccg acggtgtcac
    20041 tgggggttcc tgcccggtat atccatagcc atacttcctt ggttcacgaa gatgacacgg
    20101 aacaattggt ggatttattg gtggctgtgg tacaaaaatt agatcaaaac atggtcgatc
    20161 agttggcaga tggtacttat acataaaatg acatcaaaag acggcccttc atcgttgagg
    20221 gccgtttttc gatataaagg tccataccag ttaaatgatt ttattgagcg acaggaggct
    20281 gagccttatc ccgaggcatg tgttcgtgca aggtatttat gaggcgttct tgctccgatg
    20341 cgtcagagtt tttccagatc acctcaaata agacaccgag tccagggagt aacttttcat
    20401 ctccactttt gatggagtct agaaccatat cacgtaattc actggcctcc atgtctttaa
    20461 tattgtgata caccgcacca cgtatgggaa aattcatcaa gtttccctcc tttcttctgg
    20521 tattgttgcc aggagtcacc cggttcaccc catttgtctg gacgaattct ctggtaagtg
    20581 ctggagaagc gtatttgatg gatcgagaga ttgatagttc ggtgtgatat aatgtaaatc
    20641 aatgaagtac cgttagaaaa ccgattcaac aacaagtcgg atgcgtaata taaaatgatc
    20701 gatcattgat ctgaatggat cgagataaga acgaaaacgg ttgattggga tgaaccgaat
    20761 cgagatgaag gatcttatgt acatatgagg aggataaggc gtaacgctta tggaaatccg
    20821 aaaaattagt tccgcacgga atgatcgcgt gaaacactgg cgtaagctaa gtacacgaaa
    20881 aggaagagat gagtatggct cccttttgat tgaagggatt catctgttag aggaagccgt
    20941 gcgtgcaggt tggtctgttc gttcggtgat tataccggaa gaaggaacgg agatccttaa
    21001 ccgattgcct aaactggagg gtgtaccggt ctattcactt cttgattcca ccttccgtca
    21061 agtggtggag acacaagctc ctcagggtgt tgcagcggaa gtaggaatgg ctcttgagcg
    21121 tggccctttt caaccagagg caaataatcg ggtattgcta ttggatgcga ttcaggatcc
    21181 aggtaacttg ggtgcgatcc tacggacagc agaagccgct ggggtacgag atgtatggtt
    21241 gggttcaggt actgtggatc cttataatcc taaggtagtt cgttctgcga tgggctctct
    21301 atttcggaca cgaattcggc gagtggatct taagaaggcg attcctgatt tgcaagaact
    21361 gggttacacc gtgatcggga cgagtccacg tgcaaacaaa agtcattttg cctttgatta
    21421 cccggatcgc gtagcgatcc ttttaggaaa tgaggggaag ggcatttccc ccgtcattgg
    21481 tgccttggca gataccaatg tacgtattcc catgcccggg gaagtagaat ccctgaatgt
    21541 atcggtaaca gcgggaattt tattgtatga acttgtgcgt caaagcgagg attcccctta
    21601 aggtccccat tgcattgcgt aagggttttc gctatactat ggagcacaac tgttataatg
    21661 attggcgttg aaggagaaga gtactacaaa tcgccccacc agggagaagg tgtcatgact
    21721 ggaagcacct ttaggtgtgc gattgtagga agttcgctct ggagctgtgc ctcgaaccca
    21781 ggtttggatc tggcagtaaa ggtgaccggt tcataccgtt atcgttgaag gagtggggct
    21841 attccaggca tcgggtgctt ggatggccca accagggtgg taccacgaat ctctcgtccc
    21901 tcggacgtgg ggttttttta ttttaaagag gaaaaatgag gaggcttgac gggtatgcgt
    21961 gaacggttag aagcattgag aaaagaagca gaagtggcaa tccaagctgc tgatgacttg
    22021 gaacaattac gtgacttgcg cgtgcaatat ctcgggaaaa agggtgaatt aaccgcggtt
    22081 cttcgtggaa tgaaggatgt atcagcagag gaccgtcctg tcattggggg actcgctaac
    22141 gagattcgca gccagattga aaatctgttg gcagaaaaag agacggcaga acgggaagca
    22201 gcgttagaaa aacgcctagc ggctgaggcg attgatgtga cattagcagc ccgtccccaa
    22261 cccttaggtg gtatgcatcc cattacggcc gttgttgaac agatcgaaga tatttttaca
    22321 ggaatggggt ttgttgtagc agaagggcct gaagttgaaa cggatcggta taattttgaa
    22381 gcccttaacc tcccccagga tcaccccgct cgtgatatgc aggattcctt ttatatcacg
    22441 ccagagattt tgcttcgtac ccacacctct ccggttcaag tacgcacgat ggaagaaaag
    22501 gaaggtcaag ttcctgtgaa aattatttgc cctgggaagg tgtaccggcg ggatgacgat
    22561 gatgctaccc attcccatca attttatcaa gtggaaggtt tagtagtgga tcgtgggatt
    22621 gcaatgagcg aactgcatgg tattttggct gcctttgctg agaaaatgtt tggcatggca
    22681 cttgaaacgc gtctacgtcc aagctacttc cccttcacgg aaccgagcgt tgaaatggac
    22741 atctcttgta ttaagtgtag cggtaaaggg tgtcgcatgt gtaaacagac cggatggatc
    22801 gaaattttag gtgcaggaat ggttcatccc cgtgtattgg aaggggcggg ttacgattcg
    22861 gaacggtata ctgggtttgc ctttggtatg ggacctgacc gaatcgctct actcaagtat
    22921 ggtattgatg atattcgcca cctctatacc aatgacttaa aattcctacg tcaatttcaa
    22981 tccgtataag agataaaggg ggaagtagcg atgctagtat catatcgatg gttacaaaaa
    23041 tacgtcgacc ttaaggagac gacacccgct caattggcag aagcgttgac gcgtggtgga
    23101 attgaggtgg atgtgattga aaatcgggat ggtggcgtag aaaaagtcat cgtaggcgag
    23161 gtagtcggaa tggagccaca ccccgatgcg gataagttac gcgtttgttc agtagatgtg
    23221 ggtaccgatg aactgctgca aatcgtatgt ggagcagcca atgttgcacc cggacaaaaa
    23281 gtaccagtcg cgatccatgg tgcaaagtta ccgggcggaa taaaaatcaa aaaatcaaag
    23341 ttgcggggcg ttccttccca aggaatgatc tgttcagcaa aggaattggg tttacctgaa
    23401 aaattactgc cgaaggaaca gcaagaggga attttggtac ttcctgatga ggctggtatc
    23461 gggaccgatg taaaagagat attagggcta aatgatcatg tattggaact ggatctaaca
    23521 cccaaccgat ccgattgtct gagtatgacc ggtgtggcct atgaagtcgc tgcgttgctg
    23581 gaccgagaag taagcctacc ccaatcgaaa gaagcagcaa ccaagggtga aaagccgtta
    23641 gaactggtgt tagatgcgga ggatgactgc cccttttatg cagcacaggt cgttgaagga
    23701 ctgcaagtcg ccccatcccc tcaatggatg caaaatatct tgcttgcctc aggcattcga
    23761 cccatcaata atattgttga catcacaaac tatgtgatgt tagaaatggg tcaaccctta
    23821 catgcatttg attatgacca agtgacagat ggggagattg tggtacgtcg ggctcatcct
    23881 ggtgaacagg tagtaacatt ggatggtgta acacgggcat gtgatgcgga aaccttactg
    23941 attacggatg gaacacagcc cataggaatt gcgggtgtga tgggtggagc taattcagag
    24001 gtgaaggaga cgacaaccac ccttttgttg gagtcggcct actttgcgcc cccttctatc
    24061 cggaaagcgg cccgtaaatt ggggcttcgc tccgaagcga gtagccgatt tgaaaaggga
    24121 gtcgatccag aacggatcat tccagcatta aatcgggctg ttgagctcct cggtgaatat
    24181 gctttaggta aaccggcgtc caatgtgaaa acccaatccc ttggtggaag caatgaggtt
    24241 accgtcaccc tgcgtcatga gcgattaatt ggtgttcttg gggtgcagat tcctgaggaa
    24301 gcggtccaag atattttccg ccgacttcgt tttcctatgg aaaaagggga tggagtctat
    24361 catgttcagg taccttctcg tcgtcctgat atttccatcg aagtggattt gattgaggag
    24421 gttgcgcgct tatacggata ccatcgtata ccgactacac ttccatgggg tcaacaatct
    24481 cctggcgtgt tgacagaaga gcaacgaatt cgccgtatca ttcgtcgtac attgcaggag
    24541 gtaggtctat ttgaagtcct caactatagt ttgacctctc ccgcacggtt gtctgaagtg
    24601 gaatttcccc ttgcaacagg ttaccgaccg attcgcttaa ccatgcctat gagtgatgag
    24661 cggaaggttc tacgcacctg cctcattcct caattgattg agaccgcaga gtataatgtt
    24721 caccgacgtg aggcaggagc acagcttttt gagcttggta aaatctattt gagtgacgaa
    24781 aagaagttga cgcaactccc tgaagaacgt tgggaactgg cgggtcttat tacgggggag
    24841 acgcttgcga aacattggga tcaagaagca caaagccctg acttcttctc ggtaaaagga
    24901 attctcgaac accttttcct acggcttggg gtgaaggatg tgtccatgcg gagtgcgcgt
    24961 tataaaggct ggcatcctgg gcgaaccgca gagattttgt tagatgggac tccgattggt
    25021 ttgctgggtc aattgcaccc tcaagttgag gaggcacatg atttaggtga gacctatgcc
    25081 ttccaagtg
//
