LOCUS       NZ_FPAA01000003        23555 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Marininema halotolerans strain DSM 45789, whole genome shotgun
            sequence.
ACCESSION   NZ_FPAA01000003
VERSION     NZ_FPAA01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Marininema halotolerans
  ORGANISM  Marininema halotolerans
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Marininema.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900116235.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:20:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,453
            CDSs (total)                      :: 3,387
            Genes (coding)                    :: 3,359
            CDSs (with protein)               :: 3,359
            Genes (RNA)                       :: 66
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 28
            CDSs (without protein)            :: 28
            Pseudo Genes (ambiguous residues) :: 0 of 28
            Pseudo Genes (frameshifted)       :: 5 of 28
            Pseudo Genes (incomplete)         :: 25 of 28
            Pseudo Genes (internal stop)      :: 3 of 28
            Pseudo Genes (multiple problems)  :: 4 of 28
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:12:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 206710
            Orig. end                         :: 230265
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FPAA01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23555
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23555
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23555
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13555](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13555
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(260..279)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 21.83"
                     /tool="antismash"
     gene            856..1452
                     /locus_tag="CHX35_RS05320"
                     /old_locus_tag="SAMN05444972_103209"
     CDS             856..1452
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS05320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444972_103209"
                     /product="hypothetical protein"
                     /protein_id="WP_091835019.1"
                     /transl_table=11
                     /translation="MSRNVKKGTRRKPVAKGSKGIQKASGLKKVHPSSICTCCIAPMQK
                     ALSQIVGQQVTLVTEADQPNRELLFQTATIQTVDNYLVSMVNESLTHVVSICDVVAVLF
                     NTGPMMALAQPQASKGECLCKERPFREQFNTLINMPIDVTFKNGLVLKSGIVLRTGEGT
                     IYLQSSDATQSCVASIEKMSYFTEAKEKKGSIVLS"
     misc_feature    complement(1545..1554)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            1568..1825
                     /locus_tag="CHX35_RS05325"
                     /old_locus_tag="SAMN05444972_103210"
     CDS             1568..1825
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444972_103210"
                     /product="hypothetical protein"
                     /protein_id="WP_091835022.1"
                     /transl_table=11
                     /translation="MEVDIIPYIINGNLAIVWALAMVLLVLSIWLWVRIFVKGNDDGEW
                     RQKDTMDKVIHFVSDVVIGTVLIGTGFLSIGTMLMIVTGS"
     gene            complement(1879..2355)
                     /locus_tag="CHX35_RS05330"
                     /old_locus_tag="SAMN05444972_103211"
     CDS             complement(1879..2355)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017015.4"
                     /locus_tag="CHX35_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103211"
                     /product="DinB family protein"
                     /protein_id="WP_245838663.1"
                     /transl_table=11
                     /translation="MDLILHECNNASQANDWFISLKQALAGLTAEQASWKPEGENISSI
                     WELTSHMLYYKERLFLRLQGKETDYSLSNEETFHPSGHSQADWDQLVNRMLTLNDNLLN
                     QLQTMRETDFSNDTSDSPLWQHISNIIHHDVYHTGQMVTLRKLQKAWHPEPQNA"
     gene            2808..4274
                     /gene="proS"
                     /locus_tag="CHX35_RS05335"
                     /old_locus_tag="SAMN05444972_103212"
     CDS             2808..4274
                     /EC_number="6.1.1.15"
                     /GO_function="GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009711168.1"
                     /locus_tag="CHX35_RS05335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103212"
                     /product="proline--tRNA ligase"
                     /protein_id="WP_091835028.1"
                     /transl_table=11
                     /translation="MSDQKKNEKGITPQSENFSRWYIDAIRKADLMDYTPVRGCIAFKP
                     DGFELWERIQSKMDQRFKETGHRNAYFPMLIPESFFQKEKEHVEGFNPELPWVTEAGSE
                     KLEERLALRPTSETMIGHLYSQWIQSYRDLPVLINQWANVFRWEKRTLPFLRTSEFLWQ
                     EGHTAHATEQEAREETMQMLQIYQEVVEQELAIPVWMGQKTPSERFAGAIDTYSIEAMM
                     KDGKAVQAGTSHYLGENFARSFEIQFLDRDNQQKYVHTTSWGTSTRLIGAMIMVHGDDQ
                     GLVIPPRMAPTQLVMIPVGPGKLREKVMEKFDPLYDQLKAGGIRVRADLRDETPGWKFN
                     EWELRGVPLRLEIGPRDVDNNQVILVRRDTGEKITVGLDRVVEHVEELLVHIQKTMVQR
                     AVAFRDKHSHFTVDTLDDLKAHIVHQENVGEIAGWVLAGWCGEEECESQVKDETKFTSR
                     NIPFDAPMEKKKCIVCAKESKYTVWFGRAY"
     gene            complement(4324..4644)
                     /locus_tag="CHX35_RS05340"
                     /old_locus_tag="SAMN05444972_103213"
     CDS             complement(4324..4644)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017380358.1"
                     /locus_tag="CHX35_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103213"
                     /product="TM2 domain-containing protein"
                     /protein_id="WP_091835031.1"
                     /transl_table=11
                     /translation="MDNNIQLKQQLTPDQLQMLHGELEMRKKSKVVMYLLWIFMSTFGA
                     HRFYLGDTGYAVAMLFFGWLTLFLWPLIDVFFIGKRIDEKNTQLELEIISQIRANQQPQ
                     SA"
     gene            5134..5334
                     /locus_tag="CHX35_RS05345"
     CDS             5134..5334
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_091835034.1"
                     /transl_table=11
                     /translation="MIIIPGAQQPEIDWVNQLIIPLGADLGVFILKALVVALLASWVLK
                     KYVQPLFKSNREHEKTEKVDE"
     gene            complement(5426..5563)
                     /locus_tag="CHX35_RS17425"
     CDS             complement(5426..5563)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS17425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_176391903.1"
                     /transl_table=11
                     /translation="MRKKIQLLFGILTLLFSIGSYPFITTHVPTLTILTDFSDSDPTGT
                     "
     gene            complement(5560..6873)
                     /locus_tag="CHX35_RS05350"
                     /old_locus_tag="SAMN05444972_103214"
     CDS             complement(5560..6873)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009709839.1"
                     /locus_tag="CHX35_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103214"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_091835037.1"
                     /transl_table=11
                     /translation="MNPLDIHEIGEIIRKVRKERGLRLEDLADENISPATISNIERGVT
                     HVSMKKAHYLLSKLNIDIHNLPDLILKEQKEHQDLSFQLLSIESMCATQHSDKALQSLE
                     QLTIDDTHPYASTVYYLIGKCHIQKKNWKRAERILFKAIQLTNQGDPAHNIEAASLAEL
                     GLCSYYQNDLDSALKYTENGINSFDPQGQRPYVQFVLKQNKAVYLERLGRIGESMRVVE
                     SVWDHLHQMDESNMVLTFYWLRSELLRRSKVYEDAIYYATEGLEKARRNTNYNLMYDLW
                     TVLGSVHMDGEDWDAAKTCFSRAIELEDFLSSKHKFIITYARLGVLYIQLNAWEEAHIV
                     IEKAVQIGKEYNDIPRLTYALHTLGDYYRLQGEINEAIPHYQYCYELCNQHHLKEKEYQ
                     ALLRLAQCWEEIDEVEFQKHIRNMYEVQLQLNTLGGRF"
     gene            7032..7226
                     /locus_tag="CHX35_RS05355"
                     /old_locus_tag="SAMN05444972_103215"
     CDS             7032..7226
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009708236.1"
                     /locus_tag="CHX35_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103215"
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /protein_id="WP_091835040.1"
                     /transl_table=11
                     /translation="MHLPTIQGIILISLVALLLFGPKKLPELGRSVGKTLREFKSATSS
                     MLNDEDPRTGERKSDEGKN"
     gene            7497..7928
                     /locus_tag="CHX35_RS05360"
                     /old_locus_tag="SAMN05444972_103216"
     CDS             7497..7928
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444972_103216"
                     /product="heterocycloanthracin/sonorensin family
                     bacteriocin"
                     /protein_id="WP_176391904.1"
                     /transl_table=11
                     /translation="MDDFKKDLQELSINEFSQSDAIPWDYDDPNHPEVAQRCGGCARCA
                     GGCGARCAGGCGARCGGCGGGRCAPCAGPCGGRCAGACGVRCAGACGVRCAGCVGCVGC
                     VGCAGCGGGCGGCGGCAVPLPVPVPLPAYPPYPYPYLVP"
     aSDomain        8087..8386
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CHX35_RS05365_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.50E-43"
                     /identifier="RREFam011.1"
                     /label="CHX35_RS05365"
                     /locus_tag="CHX35_RS05365"
                     /protein_end="100"
                     /protein_start="0"
                     /score="136.5"
                     /tool="antismash"
                     /translation="MASLQSSTRLKMNKDTFVLPDAQGGVYIRNNRCSFRLDGGMIAQW
                     IEKLIPVFNGKEPLGEITAGLPKAHQERVYQIANMLYNQGMARDVSQETPHQLSE"
     gene            8087..10000
                     /locus_tag="CHX35_RS05365"
                     /old_locus_tag="SAMN05444972_103217"
     CDS             8087..10000
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHX35_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444972_103217"
                     /product="hypothetical protein"
                     /protein_id="WP_091835044.1"
                     /sec_met_domain="TIGR03693 (E-value: 6.1e-164, bitscore:
                     540.9, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     3.9e-42, bitscore: 136.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 6.8e-12,
                     bitscore: 39.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASLQSSTRLKMNKDTFVLPDAQGGVYIRNNRCSFRLDGGMIAQW
                     IEKLIPVFNGKEPLGEITAGLPKAHQERVYQIANMLYNQGMARDVSQETPHQLSEKVMN
                     AFASQLAFLDAAVGDSGASRFESYRQTKVLLMGESSLMTAVIDALWQSGLPHVHTCVTH
                     EDPLDEERMAELKSQALLMDPSITHTELSLDRKDQSSWEELIKSFDVVLYVARENGLDQ
                     LRHLQSICKKEHIALLPGICSNNLVWVGPWMDGVAIGCWESAWRRIHRQEWEEGISCTD
                     TSTIRGVLGHVMAFTCFKEITQSNELKPHNAIFLHRGESMESNWYPTFLHPEVVGSEPV
                     KKVTKAWWIAERSEEDRNEEAMFLAFADWSLPVTGIFRSWEEGALRQLPLAQCKIQVMN
                     PLSEGPADPLPESISVGITHREARKEAGLYGIEAYVSQWMKARNHEKQVTGLGAGRTLS
                     EGVCRGLQKCLVNRWKSSLEKQLPTISLLRLGAMEDRECRFYLEAWSSRGELPRFGLGE
                     EVCGFPVIWVGDHDTWYGSVGLHKSFALKRALRFALGAQQHPDANFTEEGVRVSKVNLR
                     EGSPQQLEVSMGMREVDYLPAAREILQQNQQHLKVVDWTVEPFIKQGLAGVFGVSLVEE
                     GD"
     aSDomain        8108..8344
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CHX35_RS05365_Thiopeptide_F_RRE.1"
                     /evalue="6.00E-13"
                     /identifier="RREFam004.1"
                     /label="CHX35_RS05365"
                     /locus_tag="CHX35_RS05365"
                     /protein_end="86"
                     /protein_start="7"
                     /score="39.6"
                     /tool="antismash"
                     /translation="TRLKMNKDTFVLPDAQGGVYIRNNRCSFRLDGGMIAQWIEKLIPV
                     FNGKEPLGEITAGLPKAHQERVYQIANMLYNQGM"
     gene            10001..11947
                     /locus_tag="CHX35_RS05370"
                     /old_locus_tag="SAMN05444972_103218"
     CDS             10001..11947
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013877478.1"
                     /locus_tag="CHX35_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103218"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_091835046.1"
                     /sec_met_domain="YcaO (E-value: 8e-81, bitscore: 266.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.8e-123, bitscore:
                     406.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVVGIFGDGILAERVEEDLSNDYQVIKKADVHSEVSESLRLAL
                     VLHDTWKPAVHLQAEKVFRDRGIPWLRGFIAFGQGIIGPFVQPNRRGCTQCADLRTLIA
                     GNDRKDMWVLRQSLVAHHGLNGEDIWSSENGLGFMASFLTKEVRQVLTGDQGLSQDHLY
                     YIHMKTLATSSHYVLPDGKCPLCSALPDDSSLRARITLKPSSKLSPTSFRTRSMEELKK
                     VLPRTYLDSRTGLMNGSVPDFDSPFADVTVNLPLFIGDEATAGRTHSYEESEITAILEG
                     LERHCGYSPQGVRPVIRDCYFNREGEALYPPKVGVHQRAQYEKEDFPFQPFDPEQPMDW
                     VWGWSFTQNRAILVPQLLAYYSFGCGGGFVYETSNGCAMGGSLEEAIFHGIMEIVERDA
                     FLLTWYAQLPLPRIDPSTTQDRELQWMIHRMREVAGYELHLFNATMEHGIPAVWAIAKN
                     IRSEGAHLICAAGAHLDPLRAVKSSIHELVGIIPMLDEGLTKEYDRAREMVTDATKVRE
                     MKDHSLLYCLPETETRLHFLLEGEQPVQRLDEAFPKIPVSMDITEDLTRILHPFQKRNL
                     EVIVVNQTSPEVAQLGLHCVKVLIPGMLPMTFGHHLVRLEGLERVLHVPKELGYVSQSL
                     TMNQLNPHPHPFP"
     gene            11966..13555
                     /locus_tag="CHX35_RS05375"
                     /old_locus_tag="SAMN05444972_103219"
     CDS             11966..13555
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003340794.1"
                     /locus_tag="CHX35_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103219"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_091835049.1"
                     /sec_met_domain="PF00881 (E-value: 9.8e-09, bitscore: 29.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLRQFIHDLHYDVEKVLPSDWEIDWANAPRPYKLYHEQPEVDLP
                     GNVPLTLEEAPTHSLTELQRFSYFLWYVYGLNHCIETPDFMGGSPVLRRYVPSGGALYP
                     TELYTYLKIEGLEEGIYHYNVAHHRLVLLRKGNYDALLMQMLGGRCNVKECSGVILVST
                     MFWKNFFKYHNFSYRLQGLDAGVVIGQLNEVAERLSYSTAVYYCFLDRGVNRLFGIHEE
                     EESAYALLPLYQSTLKEEGRIKDDPSATSDQLCQQIPELSLKTSSPEKKFGEYPMLIAM
                     NKAAMLDSSRDFPRPEQEKNGKRTRNGGEGGEEKSSRILFSEKKPLIYDFVKVCRQRFS
                     PGMDFVLDKVEPEHLGQLCKEVAPLLGDHNGEGGRKLWEDVDQPLFLYISLYGVKGIPN
                     GAYFYDGDHHGLKQLRTGDQRLWLQQGMTLHNVNLTQVPLCFHIAGMKDFGHDRLGERG
                     YRMNQMKAGIIVQRLLLTATALGWAGHPLLGFNSSLCDSLYNLSTCDQTCFIQIPVGPY
                     RSRAQLIGSIYG"
     misc_feature    complement(13708..13717)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            13803..15155
                     /locus_tag="CHX35_RS05380"
                     /old_locus_tag="SAMN05444972_103220"
     CDS             13803..15155
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012321.4"
                     /locus_tag="CHX35_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103220"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_176391905.1"
                     /transl_table=11
                     /translation="MQRLVCFAIMISLLMVSGCSMLMDSSPKNAAQNDRDQHVKKSSKK
                     QPALLKVEVPDELIGLNVLAGPGKYNGDTYDVNQVKKEVDHFPKNLTAEQYLVKFLALI
                     GEDYRPYIKLNNDFNTLARQNDQEPGGIRSAKLPQGKKVNVEVLFDSSGSMAGKVEGGV
                     KMDLAKQAVEKFSSQLPSDVNVALRVYGHKGSNSKSQKEISCKSTDVVYSFGPYQDKKF
                     QQSLNKFHPAGWTPLADSIRAAAKDLEEENGDNVENIIYVVSDGEETCGGDPVAEARKL
                     NGSNTDTIINIVGFDVDNAGQRALKKVADAGGGKYSKVNSKEALNEYFEGEKARLISEW
                     EKWESRNVEDSYQTESEKINALESNEKKMVDLAELEERRIRGYTEYMESKGWDDRVTID
                     IRSINSLRGIDLRNYARNTGIELRNEVRNHELDRRNETREKALNKRNKLRE"
     misc_feature    15171..15185
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            15325..16686
                     /gene="murF"
                     /locus_tag="CHX35_RS05385"
                     /old_locus_tag="SAMN05444972_103221"
     CDS             15325..16686
                     /EC_number="6.3.2.10"
                     /GO_function="GO:0008766 -
                     UDP-N-acetylmuramoylalanyl-D-glutamyl-2,
                     6-diaminopimelate-D-alanyl-D-alanine ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="murF"
                     /inference="COORDINATES: protein motif:HMM:TIGR01143.1"
                     /locus_tag="CHX35_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103221"
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="WP_245838664.1"
                     /transl_table=11
                     /translation="MRLGQFASLAGGSVVRGNPQSIVNKVVFSLQERLNPQSIKLIHPA
                     KSMERQLSYLRQQRSGVVVTVPSLKNHIPKHLMLITVASLKRSLWKVCAWQRNHSKATF
                     IGITGSSGKTTTKEMATAILMRRYRTLKSQENMNIASLMHYHHLRLDSRYQVAVLEMGM
                     KTLGDIRQQCVVARPTIGVVTCVKEAHVGHLGNSLQNVVRAKQELVDGVKPGGILIINA
                     DDPGVRKLRVNPKKHRVLTFGTRPGATYQATHIRYTKQGMEFNLGKTQYHIPIWGEHNV
                     YNALAAIAIAKQLKVPDPIIKDALRKFPVPKMRLQRVPGKNRRLLINDAYNANPSAMIA
                     GLDVLRKVSGPSFSVAVLGSMNELGSHSTKGHLQVGQRVAATRPRLLVTVGNEGKKIAQ
                     GAISAGFPRNKVHTFPNQPNVVASFLNRHVPPGAVLYFKASRSLKLEHIVNRLK"
     gene            <16867..17133
                     /locus_tag="CHX35_RS05390"
                     /old_locus_tag="SAMN05444972_103222"
                     /pseudo=""
     CDS             <16867..17133
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016103188.1"
                     /locus_tag="CHX35_RS05390"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103222"
                     /product="methyltransferase"
                     /pseudo=""
                     /sec_met_domain="Methyltransf_3 (E-value: 4.8e-11,
                     bitscore: 36.6, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DADKPNNPHYFQWALQLSRSGTQIIVDNVIRNGEVTDSNSSDPSV
                     LGVQQFYERVAAELRVSATAIQTVGSKGYVAWRLSWLQEGNKV"
     gene            complement(17309..18214)
                     /locus_tag="CHX35_RS05395"
                     /old_locus_tag="SAMN05444972_103223"
     CDS             complement(17309..18214)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007503901.1"
                     /locus_tag="CHX35_RS05395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103223"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_091835057.1"
                     /transl_table=11
                     /translation="MDFKQIQYFIEVARREHVTEAAHALHVAQSAISRQIANLETELGV
                     QLFLREGRNVRLTPLGKIFQDHAEKAMREMEIARREIDEFLDPEKGTIRVGFPSSLASH
                     ILPSVISAFRARYPHVGFQLRQGSFRHLIDSVIRGEADIAFVAPVPKEEKDVEGHIFFS
                     EKLVALLPANHELADQPAIRLDQIQEDPFVLFPNGFILHQIVLDACHQMGFHPQVSFEG
                     EDIDAIKGLVAAGLGVTLLPEVTLIESIPRATVKVPVSEPELIRTVGAVIPSNRDLPPS
                     EKLFFEFLKEFFNNLQRFRL"
     gene            18440..23032
                     /gene="gltB"
                     /locus_tag="CHX35_RS05400"
                     /old_locus_tag="SAMN05444972_103224"
     CDS             18440..23032
                     /EC_number="1.4.1.13"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="gltB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013877147.1"
                     /locus_tag="CHX35_RS05400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444972_103224"
                     /product="glutamate synthase large subunit"
                     /protein_id="WP_091835060.1"
                     /transl_table=11
                     /translation="MISKGLPQKQGLYDPAYEHDACGIGFVASLRKEATHEIVEQGLEI
                     LRRLEHRGGQKDADAGDGAGIMVQISHNYFQNILDIQLPEPGHYGVGMFFLPKEDSRRT
                     LWEKRLGEITEEEGQHVLGWRDVPVDPSCLGESSLESQPTIRQVFIALGKDQQTGLPFE
                     RKLYVIRKRLEQEAREELYVVSLSSQTLVYKGLLTPEQVGGYYMDLRNEAYTSAFSLIH
                     NRFSTNTFPSWHRAHPNRYILHNGEINTLRGNVNWMYAREKMFETDVFGDDLDKVHPIM
                     DMEGSDSAILDNCFEFLALSGRSLPHVAMMMIPEPWDKTPMDKEKHAFYEYHSCLMEPW
                     DGPTAISFCDGHQIGAVLDRNGLRPARYYVTSEDMIIFSSEVGVVDVPEETIVEKGRLQ
                     PGRMLLVDLDEGRVVSDEELKTRIATEHPYQEWLDEHVLPLAKLPDVPIMEDFDEETLF
                     RLHKAFGYTYEELSKNLAPMVTEGKDPIGSMGNDTPLAVLSDRPQLLYNYFKQSFAQVT
                     NPPIDAIREECVTSTRTNLGAEGNLLRPEPSHCHRIRLETPMISNETMAKLRGNSFPEF
                     QSETLSLLFSTKTEDPKLADILTDLFTKADRAIEKGVTLLILSDRGVNQELAAMPTLLA
                     LSGLHHHLVRQGTRTKVSLLVETGEARDVHHFSMLLGYGADAINPYLGIATLTHMVEDG
                     LIEEVTSEEAVGKYLATATDGVVKVMSKMGISTIQSYRGAQIFEAIGIGQSVIEEYFTR
                     TTSSLSGIGLDVIARETVMRHQEAYPVRDDGERSLDPGSELQWRRNGEYHAFNPMTIHT
                     LQQACRLGSYDRFKEYSKRANEEQMAFLRSLLDFKEDRKPIPLEEVESEESIVRRFKTG
                     AMSYGALSEEAHEVLAIAMNRIGAKSNSGEGGEDPARFTPDANGDARRSAIKQVASGRF
                     GVSSHYLVNADEIQIKMAQGAKPGEGGQLPGNKVYPKIADVRGSTPGVGLISPPPHHDI
                     YSIEDLAQLIHDLKNSNPAARISVKLVSKPGVGTIAAGVAKGLADVIVISGYEGGTGAS
                     PRTSIKHTGLPWELGIAEAHQTLLLNDLRDRVALETDGKMMTGRDVVIAALLGAEEFGF
                     ATAPLVVMGCIMMRACHLDTCPVGVATQNPDLRRKFTGDPDHVVNYMMFVARETREMMA
                     ELGFRSVEELVGRNDVLEMAASAKGHWKAKTLDLTPLLYQPDVPASATRYFSRPQDHRL
                     DASLDRRELIPACQSALEMGEPVEATFPIRNVDRVTGTILGSEVTKKYGLKGLPEDTIR
                     LHFQGSAGQSFGAFVPKGITLTVEGDANDYVGKGLSGGKIAVFPSPVSTFVPEEETLIG
                     NVSFYGATAGEAYIRGIAGERFCVRNSGVHAVVEGVGDHGCEYMTGGRVVILGPVGKNF
                     AAGMSGGVAYVLAEDLDGFTASCNQELVDLETLDEDEDITEVKEMIEKHVHHTGSEHAR
                     RILENWERSLPKFVKVIPHDYKEVLESIAELMDAGMSQSEARTEAFKRKQTNQPVMIAK
                     KGEGEPVLTG"
     misc_feature    23107..23124
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     misc_feature    complement(23161..23170)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
ORIGIN
        1 gtcattaacc tttggagaag atccatcctc tcttcatttt ctaggttact atacggctgc
       61 attcattttg gataagcaag ggatggatga aaagtatcgg aaatccttct acatgttgcc
      121 gcgtccaaat cgacagattt cagtttaccc tatcgatgag gggagactgg ccactttctt
      181 cgtgtatcga tcccctcggt tggaggagcc aatcactcga gaagtcactg ctcgggaact
      241 gcggcaccat tatggggatc tagagtggat ggtcccagag ctgttatcca tggtggagac
      301 agcgtcggat ctgtactttg atgaggtttc ccaggtacgg ttgcctaaat ggacgaaggg
      361 acgcgtggta ctgattggag atgcctgtca agcggtttca ttgatcgcag gacaaggggc
      421 ttccatggcg atggctggtg cttgggttct ctctcgtgaa atcgaaaaag aaccgaatct
      481 tttcgcagca ttgcaaaact atgaggaatt gatgcgccct ccgattgcca acatccaaca
      541 atccgcccaa aagcttgcga aatggtttgt cccggaaaac cacttaaccc tgtggcttca
      601 agagtccatg atgcgattgg ctgttcttcc gccatttaga cggttcgtca atctgaaccg
      661 aacgaagttg cctaaatgac tgcaatcaaa caagtgagtg cttttttgaa gctgcacttg
      721 caagaacaat tgctagagaa gagaacccga tttcatcgga tcgagaatca aatcatttcc
      781 cattgacttg caagcacaag aatcatgggt ttttcatata aatggaacat gtgaccatgg
      841 ttaggggtga tttgggtgag ccgaaacgta aaaaaaggga cacggcggaa accggtagca
      901 aaagggagca aagggatcca aaaggcgagt ggtttgaaaa aagtgcatcc ctcatccatt
      961 tgcacatgtt gcattgcacc catgcaaaag gcattaagtc aaatcgttgg tcaacaagtt
     1021 acgttagtga cagaggcgga ccaaccgaat cgagagcttc tttttcagac agcaacgatc
     1081 caaacggtag ataactacct ggtctccatg gtaaatgagt cgttaacgca tgttgtcagc
     1141 atctgtgatg tggttgccgt attatttaat acaggtccta tgatggcatt agcacaaccg
     1201 caagcaagta aaggggaatg cttgtgtaaa gagagaccct ttcgggagca gtttaatacg
     1261 ttgatcaata tgccaatcga tgtcacgttt aagaatggat tggttttgaa gtcgggcatt
     1321 gtattacgta caggggaagg caccatctat ctgcaatcca gtgatgccac gcaaagttgt
     1381 gtggcgtcca ttgaaaagat gagctacttt acagaggcaa aagagaagaa aggatcgatc
     1441 gtgttatcct aaagggtggc acaataaccc attcaaaaaa cgtggggggg cagcctacgt
     1501 ttttttgaat gggttataag aacgggatgg atgatcgtgt atactaaaaa aataatagag
     1561 ttcgatagtg gaggtggaca taattcccta tattattaat ggaaatttag cgatcgtatg
     1621 ggcattggcg atggtgttgt tagtcctgtc gatttggtta tgggttcgta tttttgtgaa
     1681 ggggaacgat gatggcgagt ggcgtcagaa agatacaatg gacaaggtga ttcattttgt
     1741 ttcggatgta gtaattggta cggttttaat cggtacaggt tttttaagta taggaactat
     1801 gctcatgatt gtaacaggga gttaaatata agtgcctccc ataggggggg cactgagctt
     1861 gattctagtg atgatttact aggcattttg aggttcagga tgccatgctt tttgcaattt
     1921 tcgcagggtg accatttgtc cagtgtgata aacatcgtga tgaatgatgt tgctaatgtg
     1981 ctgccataat ggagaatcgg atgtatcgtt gctaaaatcc gtttctctca tggtctgaag
     2041 ttgattaaga aggttgtcat tgagggttaa catgcgatta acgagttgat cccagtccgc
     2101 ttggctgtgg cccgagggat gaaacgtttc ctcattactt aaggagtagt cggtctcctt
     2161 cccttgcaag cgaagaaata gtcgttcttt gtaataaagc atgtgggaag tgagttccca
     2221 aatagaactg atgttttctc cttcaggttt ccatgaggct tgttccgcag ttaatccggc
     2281 gagtgcttgt tttaaggaga taaaccaatc gttggcctgg gaagcattgt tacattcgtg
     2341 aaggattaga tccatactgt tcaccatgat tcctccttag gtgttgatgc gttttttttc
     2401 atcccaaagg ggttcgacag atggagggtt catcctgcaa aaaaaggtat atggtttgga
     2461 attcttgact tgggtaaatg atcgtgctac gattttgcta attatttaca cagaggcaat
     2521 gaaggggatg gtagcctcat gacgcgttta agagagtcaa cccgagtctg gaaggttgat
     2581 acgctaagga gctacttccc accccagagc tgatggtgat gagccatttc ggatatcctc
     2641 ccgttatcga gggtgtggag tgaatcatac cccatgggta tggttaatca gggtggtacc
     2701 gcgggaaatt cccgtcccta tgggacaggg gatttttttg tgcaggaaaa aagggacgtt
     2761 gggttgtatc gatgaaaata accgatcttt gttaggagtg aacagtgatg agcgatcaaa
     2821 aaaagaatga aaaaggcatt accccacaat cagaaaactt ttcacgttgg tatattgatg
     2881 ccatccgtaa agcggattta atggattata cacccgtgcg tggttgcatc gcctttaaac
     2941 cggatgggtt tgagttatgg gaacgcattc agtctaaaat ggatcaacga tttaaagaga
     3001 cggggcatcg aaatgcttat ttcccgatgc tgatacccga gtcttttttt cagaaagaga
     3061 aggagcacgt agaaggcttt aatcccgagt taccctgggt aacggaagca gggagtgaaa
     3121 agctggagga acgcctagcg cttcgcccta cttctgaaac gatgattggt catttatata
     3181 gccaatggat tcaaagctat cgggatttac ctgtcttaat taatcaatgg gccaatgttt
     3241 ttcgttggga aaaaagaacc ttgccatttt tgcgtacatc ggagttcttg tggcaagaag
     3301 gtcataccgc ccatgctacc gagcaagaag cgcgggaaga gacgatgcag atgctacaaa
     3361 tttatcagga agtggtggaa caagaactcg ccatacccgt ctggatggga caaaagacgc
     3421 cgagtgaacg gtttgcaggg gcgattgata cgtattccat cgaggcgatg atgaaggatg
     3481 gaaaggcggt acaggcgggt acctctcatt atttagggga gaattttgca aggagctttg
     3541 agattcaatt ccttgatcga gataaccaac aaaagtatgt acataccact tcgtggggaa
     3601 catctacacg cctaattggt gcgatgatta tggttcacgg cgatgatcaa gggttagtaa
     3661 taccaccgcg tatggcacca actcaactgg taatgattcc tgtagggcca gggaaattac
     3721 gtgagaaggt gatggagaaa tttgatccac tttatgacca actgaaggcg ggtggtatac
     3781 gtgttcgagc ggatttgcga gatgagacgc cgggctggaa gtttaatgag tgggagctac
     3841 ggggggtacc tcttcgactt gaaatcgggc cgcgggatgt ggataacaat caggtgattc
     3901 tggtgcggcg cgatactgga gaaaaaataa ccgtcggact ggatcgtgta gttgagcatg
     3961 ttgaggaact gttggttcat attcagaaaa ccatggttca aagagcagtt gccttcagag
     4021 ataagcactc ccattttaca gtggataccc tggatgattt aaaagcccat attgttcatc
     4081 aggaaaatgt aggtgagata gcaggttggg tattagcagg ttggtgtgga gaagaagagt
     4141 gtgaatcaca ggtgaaggat gaaacaaaat ttacttcccg taatattccc tttgatgcac
     4201 ctatggaaaa gaagaaatgc atcgtttgtg ctaaggaatc caaatatacc gtctggtttg
     4261 ggcgggcgta ctaaagcgta ggtgagataa agaagagacc ttccatggaa ggtctcttct
     4321 ttatcatgca gattgtggct gttggtttgc tcgaatttgt gaaatgattt caagttccaa
     4381 ctgggtgttc ttttcatcaa ttcgtttgcc aataaaaaag acatcaatta ggggccaaag
     4441 aaaaagagtc agccagccaa aaaagagcat cgctacggca tagcctgtat caccaaggta
     4501 gaagcgatgt gccccaaaag tagacataaa gatccatagt agatacatga ccactttgct
     4561 ttttttccgc atttctagtt cgccgtgtag catttgcaac tgatcgggtg ttaattgttg
     4621 ctttaattga atgttattat ccatgatgaa ccctgcctca tataaaattt ttgagttttt
     4681 ctcctcacat atttactgaa ctttgtggga tatatcgata cagcatgcag cagatcgttt
     4741 tattaatatc tataaatgat ttcgttgctg aatggtgagt aagtatcaaa ggactatact
     4801 agtctacaaa ccattcccat tcaaagaata atagagcatc tgcgtacaaa aaaccaaaca
     4861 aagatcagtt aatcgatggg aagatccctc tttcttagaa taaaggtgaa gccatcttat
     4921 tataccaaaa attgttcggg ttttgtctgt ttaccagtga ttttgtcgaa aaaaattgaa
     4981 actcaaatta attagtcaaa aaaacccaat taatagatgg tagtttacaa atgtgtcgcc
     5041 agggaaactt gtaaaaatgc ttttaaaagg aggtagtttg tgttaaaaat taaataacag
     5101 atgccactcg gcatgtgacg tactaactaa ggagtgatta ttattccagg cgcacaacaa
     5161 ccggagattg attgggtaaa ccaattgatc atcccactcg gagcagattt aggagtattt
     5221 attttaaaag cccttgtcgt ggcattactt gcttcatggg tactcaaaaa atacgttcaa
     5281 ccgctattta aaagtaatcg tgagcatgaa aagactgaaa aagtcgatga ataagaagat
     5341 aaaaacaagc catggcgaca tggcttgttt ttatctttct ggacatttga ttttctgccc
     5401 gtattttttt gtcatcagca gtctcttacg tacctgttgg gtcactatcg gaaaagtcgg
     5461 tcaggatggt caaggtgggg acgtgagtgg tgatgaatgg ataactaccg atagagaata
     5521 aaagagtcaa aataccaaag aggagttgga ttttcttcct caaaagcgtc ctcctaacgt
     5581 attcagttgt agttgtactt catacatatt acgtatatgt ttttgaaatt ccacttcatc
     5641 gatttcttcc caacattgag cgagccgtaa caatgcttgg tattcctttt ctttaaggtg
     5701 atgttggttg cagagttcat agcagtattg atagtgggga attgcttcat taatttctcc
     5761 ttggaggcgg taataatctc ccaaggtatg taaggcgtaa gttagacgcg gaatatcatt
     5821 gtattccttc ccaatttgta ccgccttttc aataacgata tgggcttctt cccacgcatt
     5881 taattgaata tataaaacac cgagacgagc ataggtgata ataaatttat gtttactgga
     5941 taaaaagtct tctaattcaa tggcacgact aaagcaggtc tttgctgcat cccaatcttc
     6001 gccatccata tgaacactac ccaggacggt ccataaatca tacatcaagt tgtaattggt
     6061 atttcgccgc gctttttcta atccctcggt agcataatag attgcgtcct cgtagacttt
     6121 agagcgacgt agtaattcag aacgtaacca atagaaggta agtaccatat tggactcatc
     6181 catctgatga agatggtccc acaccgattc gacgacacgc atgctttcgc caattcgacc
     6241 gagcctctct aaatagacgg ctttattttg ctttaataca aattgaacat agggacgttg
     6301 accctgggga tcaaaggaat tgatgccgtt ttccgtatac tttaaagcac tatccaaatc
     6361 attttgataa tagctacaaa gtcctaattc agccaaggag gcggcttcga tattgtgggc
     6421 ggggtcgcct tgatttgtta actgaatggc tttaaagaga atgcgttcag ctcgcttcca
     6481 gttctttttt tggatatggc atttcccaat gagataatac acggtgctcg cataaggatg
     6541 ggtgtcatcg atggtaagtt gttccaagga ttgcagtgct ttatcagaat gttgcgttgc
     6601 gcacatggat tcgatggata acaattgaaa gctgaggtcc tgatgttctt tttgttcttt
     6661 caggataagg tcaggaaggt tatgtatatc aatgtttaat ttacttaaca agtagtgggc
     6721 ttttttcata ctcacatggg taacaccacg ctcaatatta ctaatggtag ctggcgatat
     6781 attttcatcg gctagatctt caagacgtaa gccacgttct ttacgtacct tacgaatgat
     6841 ttcaccaatt tcatgaatat ctaatggatt cataaaattc ctcccacctt atccctagtg
     6901 aatactcata gtttaaccta agaagaggga ttgaaaaagg attacgaggt cgagataaaa
     6961 atcaacatca atgacgatgg tcttggattc atgataggat tggaatagcg ttgaaaaagg
     7021 aggatgttgt gatgcatcta cctactattc aagggattat tttgatttcg ctggttgctc
     7081 ttcttctttt tggacccaaa aagttacctg agctcggacg ctctgtaggg aaaactttac
     7141 gggaatttaa atcagcgacc tctagcatgt taaatgacga agatccgagg acgggtgaac
     7201 ggaaaagcga cgaaggtaaa aactagggat cgatggagtg ttggtattgc aatcaggatg
     7261 cgtatgagag aggcgagaac gttggtgaat gaacccactc gctgattcca tacgtatttt
     7321 ttgtattttg tttcgaatct tcccatgcag aataggatct ttaaatatag cttgcccctg
     7381 gaaaaatagc tatcccggct cataagtatc aattatctag ataattgggg gggtgaagtg
     7441 acggcgagga ggttgaagag tagagctgac gatcagcttt ttttgggggg atagaaatgg
     7501 atgactttaa aaaagatcta caagagctaa gtattaatga attttcgcaa agtgatgcaa
     7561 ttccatggga ttatgacgat ccgaatcatc ctgaggtcgc gcaacgatgt ggtggctgtg
     7621 ctcggtgtgc agggggttgc ggtgctcggt gtgcgggtgg ttgtggtgcc cgatgtggcg
     7681 gatgcggcgg aggacggtgc gctccctgtg ctggcccatg tggaggtcgt tgtgctggtg
     7741 catgcggtgt tcgctgtgcg ggggcctgtg gtgtccgctg tgcgggctgt gtgggttgtg
     7801 tgggctgtgt gggctgtgct ggttgcggcg gcggctgtgg cggatgcggc ggttgcgctg
     7861 tgccgttacc tgtcccggtt ccattgcctg cgtacccacc gtatccttat ccttacttgg
     7921 tgccttaaaa cgaaacgggt ggatactgag ctgagcattt cattgccaat ctttcttggt
     7981 aatgaagtgc ttttttctcg tggtaagcaa gtggacggta gaagatacat aaaatggacg
     8041 ggagaggatc gattcggatt ttgaatgata gcaaggagga atgggaatgg cgagcttgca
     8101 atcttccaca cgtctcaaga tgaataaaga tacgtttgtt cttccagatg cccagggcgg
     8161 agtctatatt cgaaataatc gctgttcttt tcggttagat ggtgggatga tcgcgcaatg
     8221 gattgaaaaa ttaattccgg tttttaatgg caaggaacca ttgggcgaga taaccgcagg
     8281 attgcctaag gctcatcagg aacgcgtgta tcagatcgca aacatgttat acaaccaggg
     8341 tatggcaagg gatgtaagtc aagaaacacc ccaccagtta tctgagaaag tcatgaatgc
     8401 ctttgcttca caactggctt ttttagatgc tgctgtggga gactctgggg cctctcgttt
     8461 tgaaagttac cgccaaacaa aggtattgct tatgggtgaa agttcgttga tgacggcggt
     8521 gattgatgcg ttgtggcaat cgggtctccc tcatgtccat acctgtgtga cccatgaaga
     8581 tccgttggat gaagagagaa tggcggaact gaaatcccag gctttactca tggatccatc
     8641 gattacacac acggagctct cccttgacag aaaggatcag tcaagctggg aagaacttat
     8701 caagtcattt gatgtcgttc tctatgtggc acgagaaaat ggcttggatc aattacgcca
     8761 tttacaatcc atatgtaaaa aagagcatat cgcattgtta ccaggcattt gctccaataa
     8821 ccttgtttgg gtgggtccct ggatggatgg tgtagcgata gggtgctggg agtcagcttg
     8881 gcggcgtatt caccgtcaag agtgggaaga aggaatttcc tgcacagata cctccacgat
     8941 cagaggcgtc ctcggacatg tgatggcatt tacctgcttt aaagagatca cacaatccaa
     9001 tgaactaaaa ccccacaacg caatctttct ccatcgaggg gaatcgatgg agagcaattg
     9061 gtaccctact ttccttcacc cagaagtagt agggagtgaa cccgttaaaa aagtgactaa
     9121 ggcgtggtgg atagcggaaa gaagtgaaga ggatcggaat gaagaggcga tgtttcttgc
     9181 ctttgccgat tggtccttac ccgtcacagg tatttttcga tcctgggaag agggagcact
     9241 tcgtcaactt cctctcgctc aatgtaagat tcaagtcatg aatccactgt ctgaaggtcc
     9301 ggcggatccg ttacctgaga gcatcagtgt ggggattact catcgagaag cacgaaagga
     9361 agcgggctta tacgggatcg aagcctatgt ttctcaatgg atgaaagcga gaaatcacga
     9421 gaaacaggtt accggattgg gtgcgggtcg cacgttgtca gagggtgtgt gccgtggttt
     9481 gcaaaaatgc ctggtgaaca ggtggaaaag tagcttagag aagcaacttc ctacgatttc
     9541 attgctacgt ttgggtgcga tggaggatcg agagtgtcgg ttttatttag aagcatggtc
     9601 aagcagagga gagcttcctc gattcggtct gggtgaggag gtttgtggct ttcctgtcat
     9661 ctgggtgggg gatcatgaca catggtatgg cagcgtagga cttcataaat cctttgcttt
     9721 aaaacgagcg ttacgatttg cactcggggc tcagcaacat ccagacgcca attttactga
     9781 agaaggtgta cgggtttcaa aggtgaacct tcgtgaaggt tcaccgcaac agctggaagt
     9841 gtcaatgggg atgagggaag tggattacct cccagctgca cgtgagatat tgcaacaaaa
     9901 tcaacaacat ctcaaggttg tcgattggac cgtagagcct tttatcaagc aaggattggc
     9961 tggtgtcttt ggagtatcgt tggttgagga gggagattga gtgacggatg tagttggcat
    10021 tttcggcgat ggtatactgg cggaacgggt tgaagaagac ttgtccaatg attatcaggt
    10081 gatcaaaaag gcagatgtcc actcagaggt gtcagagtca ttacgattgg cgttagtcct
    10141 tcatgatacc tggaaacctg ctgtccacct tcaagcagaa aaggtttttc gtgatcgagg
    10201 gattccctgg ttacgaggct ttattgcctt tggccagggg attatcggac cattcgttca
    10261 accgaatcgc aggggttgca cccaatgtgc agatcttcgt accctcatcg cagggaatga
    10321 tcggaaggac atgtgggtat tacgacaaag tcttgttgct catcacggtc tcaacggtga
    10381 agatatttgg tcatcagaaa acggtttggg gtttatggcg tccttcttga cgaaggaagt
    10441 aaggcaagta ttaacgggag atcaagggtt atcccaggat cacctttact acatccatat
    10501 gaaaacattg gcgacgtcct cccattatgt acttcccgat ggaaagtgtc ctctatgcag
    10561 cgcactaccg gatgattcgt ctttgcgggc acgcatcaca ttaaagccat cttccaaact
    10621 ttctcctacc agctttcgga cacgatccat ggaggaatta aagaaggtac tcccccgtac
    10681 ttatcttgac agtcgaacgg ggttaatgaa tggtagcgtg ccggattttg atagtccctt
    10741 tgcggatgtg acggtgaacc tcccgctttt tatcggcgat gaagcgacgg cagggcgcac
    10801 tcactcctat gaggagagtg aaataacggc cattttagaa gggttagaaa ggcattgtgg
    10861 gtacagtcct caaggtgtgc gacccgtcat tcgtgattgc tatttcaatc gtgaaggaga
    10921 agctctctac ccacccaagg tgggagtcca ccaacgagcg caatatgaaa aggaagattt
    10981 cccctttcag ccttttgatc cggaacaacc gatggactgg gtatggggct ggtcttttac
    11041 tcagaatcgt gccatcttgg ttccgcaatt actggcgtat tatagctttg gttgtggagg
    11101 gggatttgtt tacgaaacat cgaatggctg tgctatgggg ggaagcctag aagaggcgat
    11161 ctttcatgga atcatggaaa ttgtcgagcg ggatgccttt ctccttacgt ggtacgcaca
    11221 gttgccactt ccacgaatcg atccctccac aacacaggat cgagagcttc agtggatgat
    11281 ccaccgcatg cgagaggtag cagggtatga actccattta tttaatgcaa ccatggaaca
    11341 tggcattcca gcggtctggg cgattgctaa aaatattcgg tcggagggtg cccatctaat
    11401 ttgtgctgct ggggctcatc ttgacccgtt gcgagcggtg aaaagttcaa ttcatgagtt
    11461 agtagggatt attccaatgc tggatgaggg gttaacaaag gaatatgatc gagcacgtga
    11521 gatggtgacg gatgccacga aagttcgcga aatgaaggat cattctctac tatattgctt
    11581 gcctgagaca gagacacgac ttcatttttt acttgaagga gagcaaccgg ttcagcgttt
    11641 ggatgaggca tttccaaaga ttcctgtctc catggatatt actgaggatt taaccaggat
    11701 tctgcatccg tttcaaaagc gaaatcttga agtgattgtg gttaatcaaa cctctcctga
    11761 agttgctcaa cttggtttac actgtgtcaa agtactcata cctgggatgc tcccgatgac
    11821 ctttgggcat catttggtgc gactggaagg gcttgaacgt gtactccatg ttccgaagga
    11881 gctgggttat gtctcacaat cattaacgat gaatcagttg aatccccatc cccatccatt
    11941 tccttaaggg agaggaggta ctctggtgca tcttcgtcaa tttatacacg atcttcatta
    12001 tgatgtggag aaagtacttc cttcagactg ggagatcgat tgggcgaatg ccccgcgacc
    12061 gtataagtta tatcatgaac agccagaggt agatctacct gggaatgtgc cgttaacctt
    12121 ggaggaggcg cctactcatt ctctgactga gttacaacgg ttcagctatt tcttgtggta
    12181 tgtctatggc ttaaatcatt gtatcgaaac ccctgatttt atgggaggtt cgcctgtttt
    12241 gcgaaggtat gttccttcgg gtggggcgtt gtatccaacg gaattgtaca cgtatttaaa
    12301 aatagaggga ttggaagaag ggatttatca ctataatgtt gctcatcatc gcttagtctt
    12361 attgcgtaaa gggaattacg acgcactgtt gatgcaaatg cttggcgggc gttgtaatgt
    12421 gaaagagtgc agtggggtta tcctggtgtc gaccatgttt tggaaaaatt tctttaagta
    12481 ccataacttt tcttaccgat tacagggatt agatgcgggg gtcgtcattg gccaattgaa
    12541 tgaagtagca gagaggcttt catattcaac agcggtatac tattgttttt tagatcgtgg
    12601 ggttaatcga ttattcggta tccatgaaga ggaagagagt gcatatgcgc ttctcccttt
    12661 atatcaatca accttgaaag aagagggtag gattaaggac gatccgagcg ctacgtcgga
    12721 ccaattgtgc caacagatcc ctgaactgtc tctaaaaacg agcagtccag aaaaaaagtt
    12781 cggtgaatat cccatgttaa ttgccatgaa caaagccgct atgttggatt cttcacgtga
    12841 ttttcctaga ccagagcaag aaaaaaacgg gaaaagaacc aggaacggtg gggagggtgg
    12901 ggaggaaaaa agttcaagga tccttttttc tgaaaaaaaa ccactcatct acgattttgt
    12961 taaagtttgt cgacagcgct tctcgccagg gatggatttt gtgctagata aagtggagcc
    13021 agaacatctg gggcagttgt gtaaggaagt agctccattg ttaggggatc ataatgggga
    13081 gggtgggagg aaactttggg aagatgtcga tcaacccctt ttcctttata tcagtttata
    13141 tggagtgaag ggcattccaa acggggctta cttttacgat ggcgatcacc atgggttaaa
    13201 gcaacttcga accggagatc agcgcctgtg gttacaacaa gggatgacac tacataatgt
    13261 caatctgact caggtgcctc tttgtttcca tattgcaggg atgaaagact ttgggcatga
    13321 tcgattggga gaacgagggt atcgcatgaa tcagatgaaa gcgggaatca ttgtacagcg
    13381 tttactgttg acggctacag cattgggatg ggcagggcat ccccttcttg gatttaactc
    13441 atccttatgt gactctcttt acaacctatc gacttgcgat cagacatgtt tcattcaaat
    13501 tccagttggt ccgtatcgga gtcgggcaca gctaatagga agtatttatg ggtaatgaac
    13561 gaagaaactc cgtagattgc ttttaatatc atacggttat agctaatcct ccattattag
    13621 gaggtttttt gttgtaatta gattgacaga atcgaaacta tttatcatat tattttattt
    13681 attgtgtaag acttcggata accaatttaa aaaaacatct ccgtaatgaa tagcattagt
    13741 tatttattta taatataata gaataaatag gatgtataca tttctaatgg aggtaattta
    13801 tgatgcaacg attagtttgt tttgcaataa tgataagttt attaatggtt agtggttgtt
    13861 cgatgttgat ggatagcagc cccaaaaatg cagctcagaa tgatagagat caacatgtta
    13921 aaaaatcatc aaaaaaacaa cccgctctcc ttaaagtaga agtacctgat gagttgatag
    13981 gtttaaatgt tttagcaggt ccaggaaaat acaatgggga tacctatgat gtaaatcaag
    14041 tgaaaaaaga ggtggaccac ttccccaaaa acttaacagc tgaacagtat ttagttaaat
    14101 tccttgcttt gataggggaa gattaccgcc catatataaa gcttaataac gattttaata
    14161 cattagcgag acagaatgac caagagccag gtggaatacg gtctgcaaaa ttaccccaag
    14221 gaaaaaaagt gaatgtggag gtgttgttcg attcaagtgg tagtatggca ggaaaggttg
    14281 aaggtggagt caagatggat cttgctaaac aagcggttga aaagttttct agtcaattgc
    14341 ctagcgatgt caacgtagca ctgcgagtct acgggcataa agggagcaat agtaaaagtc
    14401 aaaaggagat ttcttgcaag agtacagatg tagtgtattc ttttggccct tatcaagaca
    14461 aaaagtttca acagtcgtta aataaatttc atcccgcagg ttggacacct ttagcagact
    14521 ctatacgtgc cgctgcaaag gatttggaag aagagaatgg agataatgta gaaaatatca
    14581 tatatgtagt cagtgatggt gaggaaactt gcggaggaga cccagtggca gaagcaagaa
    14641 aattgaatgg atctaataca gataccatca ttaacattgt tggatttgat gttgataatg
    14701 caggacaacg cgcattgaaa aaagtggcag atgctggcgg aggtaaatac tctaaagtaa
    14761 attcaaagga agccttaaat gaatattttg aaggggaaaa ggcacggctt atttcagaat
    14821 gggagaagtg ggaaagtagg aatgtggaag actcttatca gacagagtca gaaaaaataa
    14881 atgctttaga gtctaatgaa aagaaaatgg tagatcttgc agaattagag gagaggcgta
    14941 tcaggggata taccgagtat atggaaagta aaggttggga tgatagagta accattgaca
    15001 tacgatcgat caattcgcta agggggattg acctccgtaa ttatgcgcga aatacaggga
    15061 ttgaattacg aaatgaagtc cgaaatcacg aactagatcg cagaaatgaa actcgagaaa
    15121 aagccttaaa taaacggaat aagcttcgtg aataagtata aaaatggccc atcaatcatg
    15181 ttgatgattg atgggccacg attttatttg ggccttggag cagagcccat ttcggtgaat
    15241 actgtccata tgcctcacac tgtcatcaac ggacagacat aatttatgtt gatgataggg
    15301 aagaggtgag ccaacgtgtt tcctatgcgt ttgggccagt ttgcgtcatt agccggtggg
    15361 agtgtcgtcc gtgggaaccc gcaaagcatt gtgaataaag tcgtatttag cctacaggaa
    15421 agacttaatc ctcaatccat caaactcatc catcccgcta aaagtatgga acgacaatta
    15481 agttaccttc gtcagcagcg cagtggtgta gtagtgactg tcccttcgct taaaaatcat
    15541 attccaaagc atctcatgct gatcactgtt gccagcttaa aacgatcctt atggaaggta
    15601 tgtgcatggc aacgaaacca ttcgaaagcc acctttattg gcattactgg aagctcagga
    15661 aaaacaacca ccaaagagat ggcaacagcg atattaatga ggcgataccg tacattaaaa
    15721 tcacaggaaa atatgaatat cgcatcatta atgcattatc atcatctacg tttggatagt
    15781 cgttaccaag ttgccgtact tgaaatgggc atgaagacac tcggcgacat tcgtcagcag
    15841 tgtgttgtgg caagacccac tatcggtgtt gtcacctgtg taaaagaagc acatgtgggg
    15901 cacttaggta attcacttca aaatgtagta cgtgcaaaac aagagctagt cgacggtgtg
    15961 aagcctggcg gaattcttat catcaatgca gatgatccag gagtccgtaa gttaagagtg
    16021 aatcctaaaa aacatcgcgt tcttaccttc ggcacacgac ccggagccac gtatcaggca
    16081 actcacattc gttatacaaa acaagggatg gaatttaatc ttggaaaaac ccaataccat
    16141 attccaatat ggggcgaaca caatgtctat aatgcattag cggcaatcgc cattgccaag
    16201 caacttaaag tgccagatcc aattattaaa gatgctctcc gtaaatttcc agttcctaaa
    16261 atgcgattac aacgagtccc tggtaaaaac agacgtcttt taatcaatga tgcctacaat
    16321 gccaacccct cggcgatgat tgcaggactt gacgttctaa gaaaagtgtc aggacctagt
    16381 ttcagcgttg ccgtattggg cagcatgaac gaattgggaa gtcattctac aaaggggcac
    16441 cttcaagtag ggcaaagagt ggctgccact cgtccccgat tacttgtaac agtagggaat
    16501 gaaggcaaaa aaattgcaca aggagccatc tctgcaggtt tccccagaaa taaagtgcat
    16561 acctttccaa accaacccaa tgtggtcgca agcttcctta accgtcatgt tccccctggg
    16621 gcagtattat actttaaagc ttccaggagc ttaaagctgg aacatatcgt aaaccggttg
    16681 aaataatctg aagcaagcgt aggtaaatac gcttgctttt tttgatgttt ttaacatgaa
    16741 taatgaatag gagtctatat taatagagga ataggcggtt gggcaggccg tctaagcttg
    16801 gggtggatcc tgtcaggtga tgggagcttt caagaatccc tgccttcagg catggggagt
    16861 gtcgatgatg cggataagcc aaataacccg cattattttc aatgggcatt gcaactctct
    16921 cgctctggta cgcaaataat cgtagataat gttattcgta acggggaagt aacggatagc
    16981 aatagcagtg atccgagtgt actcggtgtt caacaattct atgagagggt ggctgctgaa
    17041 ctaagagtaa gtgctacggc aatccagacg gtgggtagta aggggtatgt ggcttggcga
    17101 ttgtcttggt tacaggaggg gaataaggtt taaatggcag cagggtacat gatatgtcgt
    17161 tttcaatagg ttagttatct attaaatcga ggttgtgcta ttgtaagaga aaataagagg
    17221 cgagtataga agcaattgaa tgtaatacaa ggatcataaa aggtgaacgg ctcgtctaaa
    17281 cgagccgttc accttttttc tcaactcctc acaatcgaaa ccgctgcaaa ttattaaaga
    17341 actcctttaa aaactcgaaa aacaatttct ctgacggggg gaggtcgcgg ttgctgggga
    17401 tgacggcacc tacggttcgg attagctcgg gttcactcac gggaaccttc actgtcgcac
    17461 gggggatgct ttctattaag gtgacttcag gtaagagagt gacccccagc ccggcggcaa
    17521 cgagcccttt gatggcgtca atatcctctc cttcaaagga cacttggggg tgaaagccca
    17581 tctgatgaca ggcatccaaa acaatttgat gaaggataaa gccatttggg aagagtacaa
    17641 agggatcctc ttgaatctga tccagccgaa ttgcaggttg atcggctaat tcatgatttg
    17701 caggaagcaa ggcaacgagt ttctcagaga agaagatatg gccttcgaca tctttttctt
    17761 cctttggtac gggagcgacg aaggcaatat cggcttctcc gcggataacg gagtcaatga
    17821 gatggcgaaa ggaaccttgg cgcaactgaa atcccacgtg ggggtaacgg gcgcggaagg
    17881 cagagatgac cgaggggagg atatgggagg ctaggctact cggaaatcct acacggatcg
    17941 ttcctttttc tggatcgagg aactcgtcaa tttcccggcg ggcgatctcc atttctcgca
    18001 tcgctttctc ggcgtgatct tgaaaaattt taccaagcgg agtaagacga acgtttcgtc
    18061 cttcgcgcag aaacagctgt acccctagtt cggtttctaa gttggcaatt tgacgactaa
    18121 tcgccgattg cgctacatgt agagcatggg cagcttcggt gacatgctct cgtctggcca
    18181 cctcgataaa gtattgaatc tgcttaaaat ccaaatcgaa tcgcctcgca gaagttaatt
    18241 gatctcgaaa tgagattgat ctgatcggaa atatatattg ttaatattaa ttcgtacata
    18301 taaaataaca agaacaacca ctatcggcaa gatagtgtga catttgtaga gacaacgacg
    18361 tctctaacgg taggaatacc ttgaggtctg gactaagaca gtcgagacac tacacatcga
    18421 tgtgcgaggg gtgataacca tgatcagcaa aggattaccg caaaaacagg gtctttatga
    18481 tccagcctat gaacacgacg cgtgcgggat cggcttcgtc gccagcttac gaaaagaggc
    18541 gacccatgag attgtggaac aaggactgga gatcctccgc agattggagc atcggggtgg
    18601 acagaaggat gccgatgcgg gtgacggagc gggcatcatg gtgcaaatct cccataacta
    18661 ttttcaaaac atattggaca ttcagttgcc tgagccgggt cattatggcg taggaatgtt
    18721 ttttttacca aaagaggatt cccggcgaac cctctgggaa aaacgcttgg gtgaaatcac
    18781 ggaggaagaa ggacagcatg tattgggttg gcgggatgtc cctgtcgatc caagttgtct
    18841 aggcgaatct tcgttagaga gtcagccgac gattcgtcag gtatttatag cgctggggaa
    18901 ggatcaacaa acagggctcc cctttgaaag aaagttatat gtgattagaa aacgtctgga
    18961 acaagaagcg cgtgaggagc tttatgtggt cagcctttcg agccagacgc tggtttataa
    19021 aggactgtta acgcctgagc aagtcggagg atactatatg gatcttcgca atgaagcgta
    19081 tacctctgcc ttctcactca ttcataatcg ctttagtacc aacaccttcc caagttggca
    19141 ccgggctcac ccgaatcgat atatcctgca taatggggag attaataccc tgcgggggaa
    19201 tgtcaactgg atgtatgccc gtgaaaaaat gtttgaaacg gatgtatttg gtgatgattt
    19261 ggataaagtg catccaatca tggatatgga gggtagtgat tctgcgattt tagataactg
    19321 ctttgaattc ttagcgttat ctggacggtc gctcccccat gttgcgatga tgatgattcc
    19381 tgagccatgg gataaaacgc cgatggataa ggagaagcac gcgttttatg agtaccatag
    19441 ttgcttaatg gagccatggg atgggccgac ggcgatctct ttctgtgatg gtcaccagat
    19501 cggagcggtt cttgatcgga acgggcttcg tccagcacga tactatgtca cttcggagga
    19561 tatgattatt ttttcctctg aagtgggtgt ggtagatgtc cctgaggaga ccattgtaga
    19621 aaagggtcgt ctgcaacctg gtcggatgtt attggtcgat ctggatgagg gtcgggttgt
    19681 ctcggatgag gagttaaaaa ctcgaatcgc aaccgagcat ccctatcaag aatggttgga
    19741 tgaacatgta cttccgttag cgaagttacc cgatgtaccg atcatggaag acttcgatga
    19801 ggagacatta ttccggctgc ataaagcttt tgggtatacc tatgaagaac tatcgaaaaa
    19861 tttagcgcct atggtgaccg aaggaaaaga tcccatcggc tccatgggga atgatacgcc
    19921 cttagctgtt ctgtcagatc gacctcaact cctatataac tactttaaac agtcatttgc
    19981 tcaggtgacg aaccccccaa tcgatgcgat acgggaagaa tgtgtcacct caacacgtac
    20041 caacttagga gctgaaggga atctcttacg acctgaaccg agtcattgtc accgtattcg
    20101 tttggaaaca cccatgatat ccaacgaaac aatggctaaa ttacggggaa actcttttcc
    20161 agagttccag tcagaaaccc tttctctcct cttttctaca aagaccgagg atccaaagtt
    20221 agctgatatt cttacggatc tctttacaaa ggcagatcgt gcgatagaaa agggtgtgac
    20281 tctcctcatt ctgtctgacc gtggggtgaa tcaagagctt gcggcgatgc ctacattgct
    20341 cgcattaagt ggtttgcacc atcacttggt tcgccaggga acaaggacca aagtaagcct
    20401 tttagtggaa acgggagaag ctcgggatgt gcatcacttt tcaatgttac ttggatatgg
    20461 ggcggatgcg atcaatccat accttgggat tgctacctta acccatatgg tggaggacgg
    20521 attgattgaa gaagtgacat ccgaagaagc ggtagggaag taccttgcga cggcaacgga
    20581 tggggtcgtt aaagtgatgt ccaaaatggg catctcaacc atccaaagtt accgtggggc
    20641 tcaaatcttt gaagcgattg gcattggtca gtctgtgatc gaggaatatt ttacacggac
    20701 gacctcttcg ctttcgggta ttggtttgga tgtcattgct cgggaaacgg taatgcgtca
    20761 tcaagaagcc tatccagtac gcgatgatgg cgaacgtagt ttagatccgg gaagtgaatt
    20821 gcaatggcga cgcaatggag agtatcatgc cttcaatccg atgaccattc atacgttgca
    20881 acaagcgtgc cgtctaggaa gctatgatcg gtttaaggag tactccaagc gcgccaatga
    20941 agagcagatg gcctttttaa gaagtcttct cgattttaaa gaagatcgca aaccgatccc
    21001 acttgaggaa gtggagtccg aagaatcgat tgttcgtcgt tttaagacag gggcgatgtc
    21061 ctatggggca ttgtcagaag aagcccatga agtgctcgcg atcgcgatga accgtatcgg
    21121 cgcgaagagt aatagtggag aagggggaga agaccctgct cgctttacac ccgatgcgaa
    21181 tggagacgcg cggcgtagtg cgattaagca ggtggcgtcg ggacgttttg gagtatccag
    21241 tcactacctt gtgaatgcag atgaaattca gattaagatg gcgcaaggag caaagcctgg
    21301 tgaagggggc caacttcctg ggaataaagt ttatcctaag attgccgacg tacggggttc
    21361 tactccaggc gttggtttga tctcaccacc acctcaccac gatatttatt ccatcgagga
    21421 tttggctcag ctgatccatg acttaaaaaa tagcaaccca gcagcaagaa tcagtgtgaa
    21481 attggtatcg aaacccggtg tgggaaccat tgctgctgga gtggctaaag gtttagctga
    21541 tgtgattgtc attagtggct atgaaggagg aaccggggca tcgccgcgta cgagtattaa
    21601 gcatactgga ctcccctggg aactgggtat tgctgaggct catcagacac tccttctaaa
    21661 tgaccttcgg gatcgtgtag cccttgagac cgatgggaaa atgatgacgg gtcgagatgt
    21721 tgtcattgct gcgctacttg gtgctgagga gtttggtttt gcgacggccc cgcttgttgt
    21781 catgggatgt atcatgatgc gcgcatgcca tctggataca tgtccagttg gggtggctac
    21841 ccaaaatccg gaccttcgcc gtaagtttac gggtgatcct gatcatgtag tgaactacat
    21901 gatgtttgtt gctcgggaaa cccgggagat gatggcggag ttaggtttcc ggtcggtgga
    21961 agaacttgtg ggacgaaatg atgtgcttga gatggcagca agtgcaaaag ggcattggaa
    22021 ggcgaaaacc cttgacctaa cgccgctctt gtatcaaccc gatgtgcctg ctagtgccac
    22081 tcgttatttt tcccgtccac aagatcatcg cttggatgcg agtcttgacc gacgcgagtt
    22141 gattccggca tgtcaaagcg cgttagaaat gggagaaccc gtcgaagcaa ctttcccaat
    22201 tcgcaatgtt gatcgcgtga caggaacgat cctaggaagt gaagtgacga aaaagtacgg
    22261 tctaaagggt cttcctgaag acaccattcg ccttcatttc caaggttctg cgggtcaaag
    22321 ttttggtgcc tttgttccga aggggatcac cttgaccgtc gaaggggacg ccaatgatta
    22381 cgtaggaaaa gggttatctg gtgggaaaat tgcggtattt ccttcgccag tatccacctt
    22441 tgtgccagag gaagagacgc tgatcgggaa cgtttccttc tatggtgcga cggctggtga
    22501 agcctacatt cgcgggatcg ctggtgaacg cttctgcgta cgcaacagcg gggttcatgc
    22561 ggttgtagaa ggtgtgggtg accatggttg tgagtacatg acgggtggtc gtgttgtcat
    22621 cctgggtcct gtagggaaaa actttgcggc tgggatgtct ggtggcgtcg cctatgtgct
    22681 ggcggaggat ttggatggtt tcaccgcttc ctgtaatcag gaactcgtcg acctagagac
    22741 actcgatgag gatgaagata tcacggaagt gaaagagatg attgaaaagc atgttcatca
    22801 tactgggagt gagcatgccc gtcggatctt ggaaaattgg gagagatcct tgccgaagtt
    22861 tgtgaaagtg attccccatg attataaaga agtattggaa tccatcgcgg agttgatgga
    22921 cgcagggatg agtcaaagtg aggcaaggac tgaagccttt aaacggaaac agacgaatca
    22981 accggttatg attgcaaaaa agggtgaagg agaaccggta ctcacaggat aaggagggga
    23041 gtcacatggg aaaagccaca ggttttatgg aatatgatcg gaagacagca gcagagagag
    23101 atccattatc ccgccaagag gattggaaag agtacacctt gcctcttcct gaacaagaac
    23161 taaaaaaaca gggcgcccgc tgtatggact gcgcgactcc cttctgccat acaggaattc
    23221 caattaacgg gacggattcg ggttgcccct tgtataatct aattcccgaa tggaatgatc
    23281 ttgtctatcg tggacgttgg aaagaagcct tagaacgtct cttaaaaacc aataactttc
    23341 cggaattcac aggtcgtgtc tgtcccgctc cttgtgaagg aggttgcacg gtggcgattc
    23401 atgatccagc ggtggccatt aagagcattg agcgagaaat tatcgaccgt gggtttgcgg
    23461 aaggctggat cgttcccacc cccccaacgt ctcgtacagg caaagagatt gcaattgtag
    23521 gctctggccc ggccggcctc gctgctgcgg atcag
//
