LOCUS       NZ_FOYG01000008        22271 bp    DNA     linear   CON 22-AUG-2024
DEFINITION  Paenibacillus sp. cl130, whole genome shotgun sequence.
ACCESSION   NZ_FOYG01000008
VERSION     NZ_FOYG01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. cl130
  ORGANISM  Paenibacillus sp. cl130
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900116035.1-RS_2024_08_22
            Annotation Date                   :: 08/22/2024 03:12:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,232
            CDSs (total)                      :: 5,132
            Genes (coding)                    :: 5,055
            CDSs (with protein)               :: 5,055
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 8, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 8, 5 (16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 40 of 77
            Pseudo Genes (incomplete)         :: 49 of 77
            Pseudo Genes (internal stop)      :: 13 of 77
            Pseudo Genes (multiple problems)  :: 20 of 77
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:52:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 233437
            Orig. end                         :: 255708
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOYG01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22271
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..22271
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22271
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>22271](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..>22271)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    complement(352..365)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    complement(505..518)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     misc_feature    complement(646..660)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            complement(1387..1623)
                     /locus_tag="BM358_RS21220"
                     /old_locus_tag="SAMN04488603_108211"
     CDS             complement(1387..1623)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM358_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488603_108211"
                     /product="hypothetical protein"
                     /protein_id="WP_023990439.1"
                     /transl_table=11
                     /translation="MHGLTHLLNNAGLDPNNLSAFSLRTEVIKITANFNSWPAEVIDLY
                     LTTSKNVLEGIKEIIQSFADPNTQLKELLKKRV"
     gene            complement(1832..2233)
                     /locus_tag="BM358_RS21225"
                     /old_locus_tag="SAMN04488603_108212"
     CDS             complement(1832..2233)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012772656.1"
                     /locus_tag="BM358_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108212"
                     /product="VOC family protein"
                     /protein_id="WP_028541752.1"
                     /transl_table=11
                     /translation="MSQEIWINLPVKDVERSTAFFNEIGLHAASVGNERAKLAIGQTTI
                     LLFPDAAFEKFTGSKIADTSHTAEVIFSIGAESREEVDAFIQKVEFAGGNIFGKPSEID
                     GWMYGAGFADLDGHRWNLLYMDESKMPKR"
     misc_feature    3110..3124
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    3437..3452
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            3539..6184
                     /gene="mprF"
                     /locus_tag="BM358_RS21230"
                     /old_locus_tag="SAMN04488603_108214"
     CDS             3539..6184
                     /NRPS_PKS="Domain: LPG_synthase_C (565-854). E-value:
                     4e-91. Score: 297.0. Matches aSDomain:
                     nrpspksdomains_BM358_RS21230_LPG_synthase_C.1"
                     /codon_start=1
                     /gene="mprF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LPG_synthase_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017812061.1"
                     /locus_tag="BM358_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108214"
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="WP_028541751.1"
                     /sec_met_domain="LPG_synthase_C (E-value: 1.5e-90,
                     bitscore: 297.0, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRELLRKLKILQLFLALYRAKIIRILIPVAILVIIYVYGRHEIQN
                     INLAKIIYELRMMPVHVVIQLIIASFIAVSVMSTYDYLIRKQFKLDINWKTTYRYAWIA
                     NTFNNMIGFAGLTGLGLRTLLYKRSGVPMKTMGAAALFLSPIVLVGLSLLGCLVLVGVF
                     PVEPIFEQLPWLRIGVWGVSLYLPFFLLMQRSSLFAKWFHKGDGKLPWKVVIASLGSSV
                     LEWACAGVLFWLFTFNDLNHLPFAPVFGVYIVAAIAGIISMAPGGIGAFDLIVLLGLQT
                     LGVDPSRALTILLLFRIFYFVVPWLIGLVLATFEMSPNSKQMREMITTSLDASRNTWVK
                     FWGWPSHFGLLSDLGAWALGKLVFTSGIILLLSAATPGLIARLRFMEHVLSLPIMRFSE
                     QLSVTIGIMLIVVSRGISMRTRRAYIWTGALLLAGAIFTFAKGFDYEEAIILLIVALVL
                     WISRARFNSESASISLRSIWIWAFLAFISSLSYYVIGTHIHPAILRHLPMRAQQWFLNP
                     HEYAVTALVGLIGALILMASIFTLRPHRYTGIRPDEAGIEKLTQFIAKEDGNLLTHLLY
                     LGDKNFYWAQNDQILIPYSRVRHKLIVLGDPVGNKNLVSAAIQEFQRYADQYALTVVFY
                     QATPEYLSIYHENGYKFFKLGEEALVPLTTFTLSGKSKQNLRTAKNKSDREGQIFEVLA
                     PPYHSELLSELRQISDEWLGDRKEKAYSLGWFNEAYIQRSPLTLLRNAEGHILAFATLA
                     PAYDQNKVISIDLMRHLNDTPNGTMDVLFVRIIEWAKEQGYSYFNLGMSPLSSVGENQN
                     AHREEKLARLVFRYGGHWYGFEGLRRYKEKFSPEWQARYLAYPAGMTLPMLTLDLVRLV
                     SRRPEQVELL"
     aSDomain        5234..6100
                     /aSDomain="LPG_synthase_C"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM358_RS21230_LPG_synthase_C.1"
                     /evalue="4.00E-91"
                     /label="BM358_RS21230_LPG_synthase_C.1"
                     /locus_tag="BM358_RS21230"
                     /protein_end="854"
                     /protein_start="565"
                     /score="297.0"
                     /tool="antismash"
                     /translation="EDGNLLTHLLYLGDKNFYWAQNDQILIPYSRVRHKLIVLGDPVGN
                     KNLVSAAIQEFQRYADQYALTVVFYQATPEYLSIYHENGYKFFKLGEEALVPLTTFTLS
                     GKSKQNLRTAKNKSDREGQIFEVLAPPYHSELLSELRQISDEWLGDRKEKAYSLGWFNE
                     AYIQRSPLTLLRNAEGHILAFATLAPAYDQNKVISIDLMRHLNDTPNGTMDVLFVRIIE
                     WAKEQGYSYFNLGMSPLSSVGENQNAHREEKLARLVFRYGGHWYGFEGLRRYKEKFSPE
                     WQARYLAY"
     gene            complement(6520..6771)
                     /locus_tag="BM358_RS21235"
     CDS             complement(6520..6771)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019265.5"
                     /locus_tag="BM358_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_226887837.1"
                     /transl_table=11
                     /translation="MREYSSHRELFDYHWDTLDFVIQEEVERILLMVSNDEQRTVLELR
                     LVQGYSIKETAKILNKSEAAVKSSLYRASKHIKLRYIS"
     gene            complement(6786..7259)
                     /locus_tag="BM358_RS21240"
                     /old_locus_tag="SAMN04488603_108215"
     CDS             complement(6786..7259)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM358_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488603_108215"
                     /product="hypothetical protein"
                     /protein_id="WP_231517200.1"
                     /transl_table=11
                     /translation="MKKRMFILLLLALSTSSFSGSFVQAEGQQLASNASVKLTLSQAQQ
                     WARSNSFSLKEAQQTIDRNRINLKNAGKNLDFIPAGTGNGEEDAASSSAWKGYASSTVS
                     YLESKKQIELAQDQTDYTTMKNYYEVLLADNKVKSSEDALSLALLEEKAAEAN"
     gene            complement(7470..8144)
                     /locus_tag="BM358_RS21245"
                     /old_locus_tag="SAMN04488603_108216"
     CDS             complement(7470..8144)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346500.1"
                     /locus_tag="BM358_RS21245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108216"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_028541750.1"
                     /transl_table=11
                     /translation="MTHPTKQTFLSTWLSLLWLTVVPLLYIFYGILNHPTEHVYSLVTD
                     LDRLTPFVPSFIIPYVLWYPFIASVLIGLAFKDRTAYYRTLLALCGGLILSYIVYALFQ
                     TAVHRPDNLAQTGVINRLVWLVYSHDQPFNCFPSIHVLTSYLMLRGARVFGRTIRWAVT
                     AMSIVIIASTLLVKQHVLADVVGGILAGELLYRSAGIALSYLRGHRNRLTLKGGERHVS
                     AE"
     misc_feature    8527..8541
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.93"
                     /tool="antismash"
     gene            8599..9189
                     /locus_tag="BM358_RS21250"
                     /old_locus_tag="SAMN04488603_108218"
     CDS             8599..9189
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312080.1"
                     /locus_tag="BM358_RS21250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108218"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_049828435.1"
                     /transl_table=11
                     /translation="MGEKQLNISECLLFLQGFLTNPQRVGSVIPSSRFLAAKIVESIPW
                     NEVKAVAELGSGTGAITRFMKPHLTGSTRVLLFERDKKMRATLKTKYSDFACHSNACQL
                     IKKLNQDDIGQLDCIISGLPFFNFTSEMRETLLNQIIKALKPEGIFVAYQYSLQMKKKF
                     AEDLIIEKIEFVPFNFPPAFVYTCRKRGGNNRY"
     gene            9278..9958
                     /locus_tag="BM358_RS21255"
                     /old_locus_tag="SAMN04488603_108219"
     CDS             9278..9958
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312091.1"
                     /locus_tag="BM358_RS21255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108219"
                     /product="response regulator transcription factor"
                     /protein_id="WP_028541748.1"
                     /transl_table=11
                     /translation="MDTILVVGDDTEIRDVIHVYLRNEGYFVIEAANGLEALDLIRSIS
                     FELVILDIKMPQMDGINACIKIREISSTPIIMLSGEEEDIGKISGLTPGADDYMIKPFN
                     PLELLARVKAHLQRQSLIGKEEFNSVIFIKDLVIDKSKHTVTLKENNISLTPLEFSILE
                     LLASHPGQVFSFDKIYESVWKDPIGYSDNTVMVHIRNLREKLEEFPRDPQYIKTIWGVG
                     YKID"
     gene            9951..11099
                     /locus_tag="BM358_RS21260"
                     /old_locus_tag="SAMN04488603_108220"
     CDS             9951..11099
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019910921.1"
                     /locus_tag="BM358_RS21260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108220"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_049828434.1"
                     /transl_table=11
                     /translation="MTEHVQKPKRKKRMIQVNILIRMMLSLIIATTINNMLILLLLDIG
                     HGMESEWLLNFIPYIFPPLFMVIFIITFLALTRRIVRDLISLEQGLQIISEGNLSYRVP
                     VMRNDELGRVAFNINLMAERLQQQIEKERELEISKLEMITGISHDLRTPLTSIIGYIEL
                     LRTNSFQNKDEYTRFVQNTYNKAIHLKKLLDDLFEYTRLTSVDTRLDLNKIDVFQLLDQ
                     LIFEFEPIAQENGIHIIKDLGNSPIITVIDSKKIARAIDNLLMNALKYSVKPGTVRILM
                     KLDNKQISIEIENKGNPLTQEQENKLFNRFYKVDHSRSSEGIQTGAGLGLSIARNIIEL
                     HGGTLTLIHINNIFKFTLTLPFEGVLTRSIGSEEGHSGNLDV"
     gene            complement(11293..11991)
                     /locus_tag="BM358_RS21265"
                     /old_locus_tag="SAMN04488603_108222"
     CDS             complement(11293..11991)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312083.1"
                     /locus_tag="BM358_RS21265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108222"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_023990451.1"
                     /transl_table=11
                     /translation="MKQTFIILISALLVYTIIPTLIIRLFGIGVYKRGTGEQPIALTFD
                     DGPDPEFTPLLLDLLKKYNIKGTFFVLGRKAEKYPDLIQRMHNEGHLVGIHNYVHWSNA
                     LMSPKRVREQVNKTANVINRIIGEKAFYYRPPWGVINLFDFFLMKQFRMILWSVIVGDW
                     KSSGGKQKIKQRLLSKLRGGAVIVLHDSGQTFGADRDAPAYMLEALNEFIIEALYTGYC
                     FQRVDEKRAA"
     gene            complement(12202..12987)
                     /locus_tag="BM358_RS21270"
                     /old_locus_tag="SAMN04488603_108223"
     CDS             complement(12202..12987)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018613.5"
                     /locus_tag="BM358_RS21270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108223"
                     /product="hypothetical protein"
                     /protein_id="WP_231517199.1"
                     /transl_table=11
                     /translation="MKKGTKEKMLILTGNYGDGHIQVAQAIQDAMQIRFPHMEPVIIDF
                     MEWVHPYMNHLSRNVYLQAVKTFPQVYGYLYQKTRRQNTLSYIIKTVFSTGIGRMMKLI
                     NEIQPAIVVCTFPLAAGVMSKLKSYGSIDIHTVTIITDHTDHSSWIYPYTDQYIVGSRS
                     VRDSLIQLGVEETRIADTGIPIRPQFSQSIEREKTAKKYGLDPHMPTVLVMGGGCGMIG
                     DGSSTIQKFDLLSQPVQFIIVCGHNEKLRMKLNERHLGI"
     gene            complement(13535..>13660)
                     /locus_tag="BM358_RS21280"
                     /pseudo=""
     CDS             complement(13535..>13660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003335274.1"
                     /locus_tag="BM358_RS21280"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VWNQPLGDLDNTVGVQILNLHEKIDDLPREPRYIKTVWGVG"
     gene            complement(13662..14258)
                     /locus_tag="BM358_RS21285"
                     /old_locus_tag="SAMN04488603_108224"
     CDS             complement(13662..14258)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346505.1"
                     /locus_tag="BM358_RS21285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108224"
                     /product="DedA family protein"
                     /protein_id="WP_028541747.1"
                     /transl_table=11
                     /translation="MSYDTLIHWIAQFGYAALFFALWLGIVGMPIPDEVVVMTGGAVSK
                     VGLLQYFPAFIITYLGVISGLSLGYILGRFFGSPVLDKLRHKKNLGKHIHTSEHLLNKY
                     GNIALSFSYFFPVVRHIVPYLVGINKMSFRRYILYSYTAGLVWTSVFFVVGQFAGGHVE
                     TIGTMIYHYGIYVGLALIIGIVIFMILKSRKRSKA"
     gene            complement(14259..14540)
                     /locus_tag="BM358_RS21290"
                     /old_locus_tag="SAMN04488603_108225"
     CDS             complement(14259..14540)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820432.1"
                     /locus_tag="BM358_RS21290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108225"
                     /product="hypothetical protein"
                     /protein_id="WP_028541746.1"
                     /transl_table=11
                     /translation="MTSNQYAMFLQRFIKNPKRVGSVLPSSRFLASKMVQSVSWDDVST
                     IAEFGSGTGAITRFIELRVNRSAIDKIDFVPLNFPPAFVYTCRKKEGI"
     gene            complement(14585..15175)
                     /locus_tag="BM358_RS21295"
                     /old_locus_tag="SAMN04488603_108226"
     CDS             complement(14585..15175)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312089.1"
                     /locus_tag="BM358_RS21295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108226"
                     /product="DedA family protein"
                     /protein_id="WP_028541745.1"
                     /transl_table=11
                     /translation="MISDIVLQLVDHYGYLFFFLAFCLGPFGIPVPNEITILTGGILSN
                     NGALNPWIVYIVILAGLFTAITIAYFAGRIFGEKFKLKFQNNRHFQKAEKFFEQHGDVA
                     MCLGHFIPVIRYILPVFVGLNGTSYKKFALISYSSAFVWTATFFTFGKFLGHYILNLLD
                     LIDPKLAVVALMIAVGTFITTKWFKSKLSNFTA"
     gene            15986..16552
                     /locus_tag="BM358_RS21300"
                     /old_locus_tag="SAMN04488603_108227"
     CDS             15986..16552
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820432.1"
                     /locus_tag="BM358_RS21300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108227"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_028541744.1"
                     /transl_table=11
                     /translation="MKLNEYLLFLQSFIHSPKNVGSVIPSSRFLATKMVKQAPWNEIKA
                     VAELGSGTGAITRFINAQVSEPTKVLLFEMNETMRNNLQTEYPDFSCHPNAAQLVEAMK
                     QENIHQLDCIFSGLPFFNFERELRDTLVEQIYKALKPGGLFIAFQYSLQMKKQLSEKFI
                     IEKIDLAPFNIPPAFVYVCRKKETI"
     misc_feature    16034..16048
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            16716..17396
                     /locus_tag="BM358_RS21305"
                     /old_locus_tag="SAMN04488603_108228"
     CDS             16716..17396
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312091.1"
                     /locus_tag="BM358_RS21305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108228"
                     /product="response regulator transcription factor"
                     /protein_id="WP_023990458.1"
                     /transl_table=11
                     /translation="MNTILVVDDDSEIRDVIHVYLRNEGYHVIEAADGEEALDAIKTTP
                     IQLVILDVMMPRMDGIRACLKIREISNTPIIMLSAKEEDIDKINGLTTGADDYMIKPFN
                     PLELLARVKAQLRRQTLIGKEEFNSLILIKDLIIDKSKHSVKLKGNEISLTPLEFAILV
                     LLASHPGQVFSSEHIYENVWKAPYGFSDNTVMVHIRNLREKLEQFPRDPQYIKTVWGVG
                     YKIE"
     gene            17389..18492
                     /locus_tag="BM358_RS21310"
                     /old_locus_tag="SAMN04488603_108229"
     CDS             17389..18492
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312092.1"
                     /locus_tag="BM358_RS21310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108229"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_028541743.1"
                     /transl_table=11
                     /translation="MNEHVQKSKRKKRIQVNILIRMVLSFIIAIAINDILILLFLKISS
                     TMEWHWFRNFFPYLLTPLFMVTFIFTFLVLTRRIVRDLITLEQGLQIISEGNLKYRVPV
                     VRQDELGRVALNINRMTERLEQQIVKEREIEKSKMDLITGISHDLRTPLTSIIGYIELL
                     RTDSYQDKDEYTRFVQNTYNKAIHLKKLLDDLFEYTRLTSVDTHLNLRRINLFQLLDQL
                     LFEFEPIAQENGVYIVKDIGDSPVVTSIDSDKIARAIDNLLMNALKYSLKPGGICIRLK
                     TSPEQITIEVENKGAPLTQDQEEKLFDRFYKVDHSRSSEGIQTGAGLGLSIARNIVELH
                     QGTLTLNHSHNVFTFQLNLPFVNNSSS"
     gene            complement(18585..18860)
                     /locus_tag="BM358_RS21315"
                     /old_locus_tag="SAMN04488603_108230"
     CDS             complement(18585..18860)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM358_RS21315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488603_108230"
                     /product="hypothetical protein"
                     /protein_id="WP_023990460.1"
                     /transl_table=11
                     /translation="MASLKEVNNELVRDLIEEFNKIKMDNNLTLVQKEHLKTALLLELS
                     RTTGRLVQIYGQWTKDGQIIRDNSLKKKIDHLSTLYATFSILRKWL"
     gene            complement(18835..19089)
                     /locus_tag="BM358_RS21320"
                     /old_locus_tag="SAMN04488603_108231"
     CDS             complement(18835..19089)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM358_RS21320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488603_108231"
                     /product="hypothetical protein"
                     /protein_id="WP_028541742.1"
                     /transl_table=11
                     /translation="MVDIIDSLKDYVHKGQLNGKKNLAKPNLDKLSYFLTICGKSIYKS
                     AELEYKDVQTEVCLVPGYQEIIRKREALGEDNGFIERSE"
     gene            complement(19236..19559)
                     /locus_tag="BM358_RS21325"
                     /old_locus_tag="SAMN04488603_108232"
     CDS             complement(19236..19559)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM358_RS21325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488603_108232"
                     /product="hypothetical protein"
                     /protein_id="WP_028541741.1"
                     /transl_table=11
                     /translation="MTLDTLEALEQQIKVIKHDNGIYKLRTITDEEDIIPVPAIGKLVY
                     NIEEEESTIRKEDVNGTELDYEEYDEGGDYFVPLPTNIKPIIDSLNSLDDRRVQTVINS
                     YYC"
     gene            complement(20001..>22271)
                     /locus_tag="BM358_RS21330"
                     /old_locus_tag="SAMN04488603_108233"
     CDS             complement(20001..>22271)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PCP (232-300). E-value: 1.9e-25. Score:
                     80.8. Matches aSDomain: nrpspksdomains_BM358_RS21330_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (316-600). E-value:
                     1.5e-103. Score: 337.9. Matches aSDomain:
                     nrpspksdomains_BM358_RS21330_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312094.1"
                     /locus_tag="BM358_RS21330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488603_108233"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_143109568.1"
                     /sec_met_domain="AMP-binding (E-value: 5.1e-48, bitscore:
                     157.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-18, bitscore:
                     61.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.6e-86, bitscore:
                     283.2, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GSLFRIINAYGVTEAAIDSSFYDEELAKLPQTGHVPIGKAWLNAK
                     FYIVDAHLNPVPVGVLGELVIGGVGVARGYLNRPELTEEKFVDSPFAAGERLYRTGDLA
                     RWMEDGNVDFIGRIDNQAKIRGYRIETGEVEAKLLSVGGVKEAVVVVREDQEGQKALCA
                     YYTAEEGLTAADLKRAISSELPGYMIPSYFVELERLPLTPNGKIDRKALPAPEGGASAG
                     REYVAPRTELEAKLVAIWQDVLGPVTIGVTDNFFDLGGHSLRATTLVSKLHKELRVDLP
                     LRDVFRHSTIEAMAEAISQLERQEYLSIPVLDKRDYYPLSSVQKRLYIQQQMEGAELSY
                     NMSGMTVLVGRLERNQFEAALKGLIARHEILRTGFEMVDGEPVQRIYPDLKFAVEYTKA
                     TESETKSIVDGFVRVFDLERPPLLRVGLVEWEAERHLLMLDIHHIVTDGMSMGIFVEEL
                     LRLYNGETLEPLRIQYKEFAAWQQSEPVKERLKRQEAYWLDVLEGELPTLELPTDFVRP
                     AARSFEGDVLPFSIDKQMTDSLQRIADENGATLYMVLLAAYSILLSKYSGQEDFIVGTP
                     VSGRTHADLEPLIGMFVNTLAIRHYPSGEKTFLAYLNEVKETMLGAYDHQDYPFEELVK
                     KLQAPRDQSRNPVFDVMFALETKEDNVQSFGDIKIESYPETHTVSQFDLTLVISLLDEG
                     MNGQFEYATKLFTLNLIDNFAQDLLVIITQICEQPSVLLKDISLNGQSEQEQDVLEAID
                     IIF"
     CDS_motif       complement(20304..20423)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM358_RS21330_0007"
                     /evalue="8.50E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BM358_RS21330"
                     /protein_end="655"
                     /protein_start="615"
                     /score="72.8"
                     /tool="antismash"
                     /translation="KETMLGAYDHQDYPFEELVKKLQAPRDQSRNPVFDVMFAL"
     aSDomain        complement(20469..21320)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM358_RS21330_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.50E-103"
                     /label="BM358_RS21330_Condensation_LCL.1"
                     /locus_tag="BM358_RS21330"
                     /protein_end="600"
                     /protein_start="316"
                     /score="337.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVTDG"
                     /tool="antismash"
                     /translation="YYPLSSVQKRLYIQQQMEGAELSYNMSGMTVLVGRLERNQFEAAL
                     KGLIARHEILRTGFEMVDGEPVQRIYPDLKFAVEYTKATESETKSIVDGFVRVFDLERP
                     PLLRVGLVEWEAERHLLMLDIHHIVTDGMSMGIFVEELLRLYNGETLEPLRIQYKEFAA
                     WQQSEPVKERLKRQEAYWLDVLEGELPTLELPTDFVRPAARSFEGDVLPFSIDKQMTDS
                     LQRIADENGATLYMVLLAAYSILLSKYSGQEDFIVGTPVSGRTHADLEPLIGMFVNTLA
                     IRH"
     CDS_motif       complement(20472..20561)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM358_RS21330_0006"
                     /evalue="5.80E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="BM358_RS21330"
                     /protein_end="599"
                     /protein_start="569"
                     /score="54.0"
                     /tool="antismash"
                     /translation="DFIVGTPVSGRTHADLEPLIGMFVNTLAIR"
     CDS_motif       complement(20820..20852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM358_RS21330_0005"
                     /evalue="1.00E-02"
                     /label="C4_LCL_164-176"
                     /locus_tag="BM358_RS21330"
                     /protein_end="483"
                     /protein_start="472"
                     /score="8.7"
                     /tool="antismash"
                     /translation="QYKEFAAWQQS"
     CDS_motif       complement(20883..20948)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM358_RS21330_0004"
                     /evalue="1.20E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="BM358_RS21330"
                     /protein_end="462"
                     /protein_start="440"
                     /score="33.7"
                     /tool="antismash"
                     /translation="IHHIVTDGMSMGIFVEELLRLY"
     CDS_motif       complement(21144..21251)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM358_RS21330_0003"
                     /evalue="2.70E-12"
                     /label="C2_dual_024-063"
                     /locus_tag="BM358_RS21330"
                     /protein_end="375"
                     /protein_start="339"
                     /score="39.2"
                     /tool="antismash"
                     /translation="YNMSGMTVLVGRLERNQFEAALKGLIARHEILRTGF"
     aSDomain        complement(21369..21572)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM358_RS21330_PCP.1"
                     /evalue="1.90E-25"
                     /label="BM358_RS21330_PCP.1"
                     /locus_tag="BM358_RS21330"
                     /protein_end="300"
                     /protein_start="232"
                     /score="80.8"
                     /tool="antismash"
                     /translation="EAKLVAIWQDVLGPVTIGVTDNFFDLGGHSLRATTLVSKLHKELR
                     VDLPLRDVFRHSTIEAMAEAISQ"
     CDS_motif       complement(21864..21929)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM358_RS21330_0002"
                     /evalue="1.50E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BM358_RS21330"
                     /protein_end="135"
                     /protein_start="113"
                     /score="33.1"
                     /tool="antismash"
                     /translation="FIGRIDNQAKIRGYRIETGEVE"
     CDS_motif       complement(22011..22100)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM358_RS21330_0001"
                     /evalue="1.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="BM358_RS21330"
                     /protein_end="86"
                     /protein_start="56"
                     /score="55.7"
                     /tool="antismash"
                     /translation="PVGVLGELVIGGVGVARGYLNRPELTEEKF"
ORIGIN
        1 cccgttacag agatgtctgg aacagtggaa ttccggcgat ctcgacgcca ttctatactt
       61 ggaaaagctc gaaatcgtat ccgggcgatg gaaagaatga ttacgcctcc aataaagtgt
      121 cggttgaaca agagtgggcg gacaactcta ctacagcagg acagccaacc tcgaacaatg
      181 ctctcttaaa cggaaatacc tatcatacgc ctgactattc aatgaaatcg ggcatggatg
      241 tgattgattt tccgatgcat tgggcattca agaccgcgca ggaagcattc aatatgagaa
      301 gtggtgatca atactataat gatgctacct ggaatgtaac ctatatcgac tcgcatgact
      361 atgcgcccga ccaggctccg gaaaatcaaa gatttgcggg cacacaggac acttgggccg
      421 agaatctcga tctgatgttc accttccgcg gaatacccgc tatcttctat ggttccgaaa
      481 tcgaattcca aaagggggct gtcattgatc cgggtccaaa cgcaccgcta agcaaaacgg
      541 gacgggctta ttacggcgat cacatggaag gcagtgttac agtacaagat tacggcaaat
      601 acacaaatgc taccggcacg cttgcggaat cgctcaacca tcctctggcc aaacatatca
      661 gacagcttaa tttaatcaga agagctgttc ccgccttgca aaaaggacag tattccacag
      721 agaatgtaac gggcaatctg gcgtttaaga gaagatatac cgacagcgcc aaaggcattg
      781 acagctttgc attggtcacg atttcaggaa acgccacatt taccggaatt ccgaacggaa
      841 cctatgtgga tgcggtgact ggtaattcca aaaccgttac tgatggcaag attaccctga
      901 catgctccgg caaaggaaac gcaagggtat atgtattgaa tggcagcggt ggaattggag
      961 aaacgggaac ctatctgaag taaacggcag tatgtcttag ttaactgaag caacctcagt
     1021 tcggtattgc accgtgctaa ggttgcttcc aattaaaaag tatatccaag agagagagtc
     1081 aggatattgc tctggactaa atttttaacg gatggggagt gaaccaagat gcaccaacga
     1141 cagcttctat gtgcgtacat tcctccgtat atttaatgac caacaaccat caagtattaa
     1201 cgggttctga ccggtcatcc ggatatgttc taccgcatac aacgggtaca agcgttagac
     1261 caaaagtacc taaagcatat gataattgag gatgtccttc atgaatgtat aatgctattg
     1321 ccataataat gataggcaaa actgtaatac aatcattata gttgtttcct ccatttgcat
     1381 tgtatttcac acacgtttct ttaacaattc tttcagctgt gtgttcgggt cagcaaaaga
     1441 ctgaataatc tcctttatac cttctagaac gttttttgaa gttgttagat acaaatctat
     1501 tacttccgca ggccagctgt taaagttggc cgtgattttt ataacttctg ttcttaaaga
     1561 aaaagcactt aaattattag ggtctaatcc cgcattatta agcaaatggg tcaatccatg
     1621 cacaagttct actcttgagc gatcgagatt ttcaaaagga ttggaaatat ctaatatatc
     1681 ccttagctta gggatagccc aggtgatttg tataaattta acccacgaat ttttccttct
     1741 aagcaacgat tttgatttga attacggata tgagattata gggggtgtaa aaaacgccgg
     1801 tgaccttaag gaggtgaccg gcgttttcat attagcgttt cggcattttg ctctcatcca
     1861 tgtacagcag gttccagcgg tgaccgtcca ggtcggcaaa tcctgcgccg tacatccagc
     1921 cgtcaatttc actcggtttg ccaaagatgt ttcctccggc aaactctact ttttgaataa
     1981 aggcatctac ttcttctctg ctttcagcgc caatggaaaa tattacttct gcggtatggg
     2041 aagtatctgc gatttttgaa cctgtaaatt tctcaaacgc cgcatccggg aacagcagaa
     2101 tcgttgtttg gcctatggca agcttggctc tctcgttacc aacgctagcc gcatgtaatc
     2161 caatctcatt gaaaaaggca gttgacctct caacatcttt gaccggcaga ttaatccaga
     2221 tctcctgtga catggctgta gcctcctgga atatattttc aactgctcct actatactct
     2281 acttctggca gcagaagcga atcttataaa agaaaccgca aggtatcgat ctagccaaga
     2341 atggatttcg catcaaagta atgactctct tacaacaatt ctgcactctt caagttcttc
     2401 gggatccgta tctaggtaaa gaagcttcca gtcagttggg tatattgaat gcgcatgccg
     2461 ataatggata cccaaaggtg tcactgaagc aaaatcatat attttcaaag aatctgattt
     2521 taggggcatc atcgttcctc cctttagctt ataactatat ttattggcaa taagattttt
     2581 tatatttata aaacaataaa atatccgagt atcaataaat tgaatacgat tcagtcaaga
     2641 atatattcaa ctcttcatgc gtagttagag ctttcacact gaattccgtc ttttaaccga
     2701 gatggggggc gctgaagctt aatcatggag cttgcaactg gagcacttgc gtaggaagcc
     2761 ctgttcaact ttaacggtgg agagtcttag cgaaagaatc tccatttcaa gttattactt
     2821 agctatacaa attctttaga ttttctttag aaatatactc attaattcct tagttttttt
     2881 tattatgctt tctgcattga aagaaagaga gagaagtaaa aaatggttag atataaccta
     2941 aaaatttatt aattcctagg gctatctatt cttatttcgc cctctctctg agttctttta
     3001 gaatacaatc ccatatgaaa ctacatctag tatcctcgta tctggcccac ggtaaggatg
     3061 aagcgtacgt agccacaata attgaacata aacccgcttg tatactccca tcaacaatgc
     3121 cgatcgtacg gagttgttca tagagattgc gctaggtgta atcatcacac agtaccccgc
     3181 aggcagctta ttcacagcca ctgctaactg aaccaagtag tttgcttgcc aggcggatat
     3241 ggaagctata cttaacctgc tagtttattt tgctgacgct atttgtccta gcaacgcagt
     3301 ttgaatgaaa atgctaacgg tttactgctg ggttcctccc caagagtact gatggcttgg
     3361 gtcacggacg aagatctcct tcatttactg gatctaatta acccccgacc ccgaaaatgt
     3421 ctggattgga ggaccgctca cgaatctttc acagaagtcc tgtcgcactt ggtttgacaa
     3481 tccgtcttgt attaaaaata tcgatattat tttgtccgaa ggtggagtcg acgacacaat
     3541 gagagaattg cttcgaaagc ttaaaatttt acagctattt ttggctttgt accgtgctaa
     3601 aattattagg atactgattc ctgtagctat tttagtcatt atctatgtat atggaagaca
     3661 cgaaattcag aatattaact tagctaaaat tatttatgaa ttacgcatga tgcccgttca
     3721 tgtcgttatt caattgatca ttgcttcttt tatagcggta tctgtaatga gtacttatga
     3781 ttatttaata cgaaaacaat ttaagcttga tatcaattgg aaaacgactt atcgatatgc
     3841 atggatagcc aatacattta acaatatgat tgggttcgct ggtcttaccg gtctaggact
     3901 acgtacatta ctgtataaga gaagtggcgt tcctatgaaa acaatgggag ctgctgcact
     3961 ctttttatcg cctatcgtat tagtcggtct atctttactt ggctgtcttg tactggtcgg
     4021 tgtttttcct gtagaaccta tttttgaaca acttccttgg cttcgtatcg gtgtatgggg
     4081 agtttcattg tacttaccgt tcttcctatt aatgcaacga tcttccctgt tcgccaaatg
     4141 gtttcataag ggcgatggca agttaccttg gaaagtagtc atcgcttctc taggttcctc
     4201 tgttctagag tgggcttgtg caggggtatt attttggtta ttcactttta atgatctgaa
     4261 tcatttaccg tttgccccgg tattcggtgt gtatattgta gcagcaattg cagggattat
     4321 tagtatggcg ccaggtggta ttggagcatt tgatctgatc gtgttgcttg gacttcagac
     4381 attaggtgtt gatccatcac gtgcactaac gattttgtta ttgttccgca ttttttactt
     4441 tgtagttcct tggttgatcg gtcttgtgct agctacgttt gagatgagtc cgaacagtaa
     4501 acaaatgcgt gaaatgatta caactagtct ggacgcttca cgtaacacat gggtcaaatt
     4561 ctggggctgg ccttctcatt tcggtctact tagtgatcta ggagcatggg cgcttggaaa
     4621 gttagtattc accagtggta tcatattact actttctgcg gctaccccag gcctaattgc
     4681 tcgcctacgt tttatggaac atgtgttatc tttacctatt atgcgttttt cagaacagtt
     4741 atctgtgact atcggtatta tgcttattgt cgtatcacgt ggtatttcaa tgcgtactcg
     4801 tcgcgcttac atatggacag gagcattgtt gttagcaggt gctatcttca catttgctaa
     4861 agggttcgat tacgaggaag ctattatttt acttattgtt gcattggtgc tatggatatc
     4921 tcgggctcga tttaacagtg aaagtgctag tatttcttta cgtagtatct ggatttgggc
     4981 gttccttgct tttatctcat cgttatcgta ttacgttatt ggtacacata ttcatccagc
     5041 tattttgcga catctaccaa tgcgtgctca acaatggttt ttgaacccgc atgaatatgc
     5101 agtgacggcc cttgttggat taatcggtgc tttaatttta atggcatcta tattcacctt
     5161 acgcccgcat cgctacacag gaatacgtcc agatgaggcg ggtatagaga aattaactca
     5221 atttattgcc aaagaagacg gtaatctttt gactcatctt ctctatctag gagacaaaaa
     5281 tttttattgg gcgcaaaatg atcaaatttt aattccctat tctcgagtgc gtcacaaatt
     5341 aattgtactt ggcgacccag ttggtaataa aaatcttgtc tctgctgcga ttcaagaatt
     5401 tcagaggtat gcggatcagt atgcattaac cgttgttttt tatcaagcaa cacctgaata
     5461 tctatcgatc tatcatgaga atggttacaa attcttcaaa ctaggcgaag aagctttggt
     5521 tcctctaact acattcacat taagtgggaa aagtaagcag aacttgcgaa ctgctaaaaa
     5581 taaatcagat cgtgaaggtc aaatatttga agtgcttgcc ccaccctatc attcagaatt
     5641 actgtctgaa ttacgtcaga tttcggatga gtggctaggc gatcgtaaag aaaaagctta
     5701 ttctttaggc tggttcaacg aagcgtatat tcaacgctct cccttaacat tgcttcgtaa
     5761 tgctgagggt cacattttgg cttttgcaac attagctcca gcttatgacc aaaataaagt
     5821 gatctcaatt gatctgatgc gccatttgaa tgatacaccg aatggaacga tggatgtgtt
     5881 atttgtacgt ataattgaat gggcaaaaga acaaggttat tcttatttca atttgggtat
     5941 gtctcctctc tccagtgtgg gtgaaaatca gaatgcgcat cgtgaagaaa aattagctcg
     6001 gctggtgttc cgatatggtg ggcactggta tggatttgag ggattgcgcc gttacaagga
     6061 aaaattctca cctgaatggc aagcaagata tttagcttat ccggcaggta tgacacttcc
     6121 aatgcttacg ctggatctgg tccgactggt atctcgtcgt ccagaacaag tagagcttct
     6181 ttaaccttca gaataaattc tttggatagg ctacagttac gtggactgaa aaaatgaggg
     6241 caatggaaag aaagcaatta tttttcacgg ttagatattc agaattcctt cacatcctaa
     6301 ggtggtcact tgaccacctt tttaatgttt tgactcaact attctaccta cactcttcta
     6361 gacataaaaa acgtggttta ttgtattaga taacagataa actagaggta ttggttggat
     6421 caataacaag atatttaagg atcagagctt gaaaaaaaag cttttttagc aaaaagaata
     6481 ctgtcagtcc tactgcttat taggttcttc ccaatcagtt catgaaatat atcttaattt
     6541 aatatgttta gaagctctgt acagcgacga cttcacggca gcttcgctct tgtttaaaat
     6601 tttagctgtt tcttttatgg agtatccttg gactaggcgc aattcgagta cagtcctttg
     6661 ctcgtcatta cttaccatca aaagaattcg ctcgacttcc tcttgaatta caaaatcgag
     6721 ggtatcccag tgataatcaa atagttctct atgtgaagag tattctctca tcttttttcg
     6781 ttttcttaat tcgcctcagc agctttttcc tccaataatg caagcgaaag tgcatcctca
     6841 ctgctcttca ccttgttatc agccagaagt acctcataat agttcttcat tgtagtgtag
     6901 tctgtctgat cttgggcaag ctcgatttgc ttcttggatt ccagataaga aaccgtcgat
     6961 gaggcatacc ccttccatgc tgaactactg gccgcatcct cttctccatt acctgtacct
     7021 gcgggaatga agtccagatt cttacctgca tttttcaagt taatccgatt gcgatctatc
     7081 gtttgctggg cctccttcaa gctaaagcta ttggatcgcg cccattgctg ggcttgactc
     7141 aatgttagtt tcacacttgc attggaagcc aattgctgcc cctctgcttg aacaaaggac
     7201 cctgaaaaag aactggttga taaggccaac agcaataaaa tgaacatacg ttttttcata
     7261 gaaccccctc tttctatttt taaataattg tacaaacaca ttcttatatg aattatctat
     7321 tgttctcttt tgagcaacta caaatgaatc atagacacgt gcagattgct ttctgctttg
     7381 gctaaaagta tttcgggatg aaacgatcta gcaatgtaat catatgtcag ggttttctca
     7441 taaaatgaga tatgaatgag cgtctctctt tactcagcag aaacatgacg ctcgcctcct
     7501 ttcagagtca ggcgatttct atgtccccgt aggtatgata aggctatgcc cgccgatcgg
     7561 tacaacagct ctccggctag gataccgcca acgacatccg ctagtacatg ctgcttgacc
     7621 agcaaagtgg acgctataat gacaatagac atcgcggtga ctgcccagcg aatcgttctt
     7681 ccgaataccc ttgctccacg aagcatcagg tagctggtta gcacatgaat gcttgggaaa
     7741 cagttaaacg gctggtcatg gctgtacacc aaccagacca aacggttgat gacgcctgtc
     7801 tgggctagat tgtctggacg gtgaacagcc gtttggaaaa gggcatagac gatataagaa
     7861 aggatcagcc ctccacagag cgcaagtagc gtccggtaat aagctgttct gtccttgaac
     7921 gcaagtccga tcagtacaga tgcaatgaac gggtaccaaa gaacataagg aataataaag
     7981 gacggaacga atggcgttag gcgatctaga tccgttacga ggctatagac gtgttcggta
     8041 ggatggttaa gtataccgta aaaaatatac aataacggaa ccactgtaag ccatagaaga
     8101 gacagccaag ttgaaaggaa ggtttgtttt gtagggtgag tcacgttatc atctcctgat
     8161 taggttcatc tatagcaatg aacccatcat aatgataaac tctgaagaac tttagaggat
     8221 ttttctaaag aattccttaa cattagttgg taaggggtat tccctctcac atcttattta
     8281 tagggaatct tatcaacaat ttacgtaata aaaagcctcg ccaacttttt tgttggcaag
     8341 gctttttggg ttcttcaatc agatcagctt tctgattttc atgcacttct tgcagacttc
     8401 gagtctgaat agtgtacata tcttcagatt ttctttagat atatcctcgt aaaatcctta
     8461 gattttttcg ttactatttt tatattgata taaataacaa aacgaggaga tatggcaata
     8521 tgttttggat tattccttcc agttgttcgg tatatcatcc ctttatttgt tgggtaccca
     8581 aaagggagaa attaaataat gggggaaaaa cagttgaata tcagtgaatg tctacttttt
     8641 ttgcaaggat ttctcacaaa tccacaacga gtaggaagtg ttatacctag ctcccgattt
     8701 ctagcagcta aaatcgttga gtctatacca tggaatgagg taaaggcagt cgcagaactc
     8761 gggtcaggta caggtgctat tacacgtttc atgaagccac atttaaccgg atcaacaaga
     8821 gtgctattgt tcgaaaggga taagaaaatg agagctactc tgaagacaaa atactcggat
     8881 ttcgcgtgtc attcaaacgc ttgccaatta atcaaaaaat tgaatcaaga tgacatcggc
     8941 cagcttgatt gtattattag cggattgcca ttttttaatt ttacgagtga aatgcgagaa
     9001 accttactca atcagattat taaggcacta aaaccagaag ggatttttgt cgcttatcag
     9061 tactcacttc aaatgaaaaa aaaatttgcc gaagatttaa tcatcgaaaa aatcgagttc
     9121 gtacctttca atttccctcc agcttttgta tatacctgtc gcaaaagggg gggcaataat
     9181 cggtattaat aaacttttcg tagcaatcat tgggtttgcc ttaattatag aattttagta
     9241 gccgtaatca taaaaagtag gaaaggagca tcatgtaatg gatacaatac ttgttgtagg
     9301 tgacgataca gagattcgag atgtcattca cgtttatttg cgcaatgaag gatactttgt
     9361 catagaagct gcaaatggtc tggaagcgtt agatttaata agatcaatct ctttcgaact
     9421 tgtcatctta gatattaaga tgccacaaat ggatggcatt aatgcttgca ttaaaataag
     9481 ggaaatatcg agcaccccca ttatcatgct atcgggggag gaagaagata ttggtaaaat
     9541 ttcgggtctt actcccggtg cggacgatta catgataaaa ccctttaatc cgttagaatt
     9601 actcgctcga gtaaaagctc atttgcagcg acaatcatta ataggaaaag aagaatttaa
     9661 ttctgttata ttcatcaaag atcttgtgat cgataagagt aaacataccg ttacattgaa
     9721 agaaaataac atttcgctga cccctcttga gttttcaatt ctagagttgc ttgcaagcca
     9781 ccctgggcaa gtatttagct ttgataagat ttacgaaagc gtgtggaaag atcctattgg
     9841 gtattccgat aataccgtga tggtccatat tcgtaattta cgagagaaat tagaggagtt
     9901 ccccagagat cctcagtata ttaaaacgat ttggggagtt ggttataaaa ttgactgaac
     9961 atgtgcaaaa accaaaacga aaaaaaagga tgattcaggt caatatttta atcagaatga
    10021 tgctaagtct cattatcgcc acaaccataa ataacatgct cattttactt ttactggata
    10081 ttggccatgg catggaatcc gagtggctcc tcaatttcat tccgtatatt ttcccccccc
    10141 tgtttatggt tatctttatt attactttcc tagctttaac tcgacgaatc gtaagagact
    10201 taatttcgtt ggagcagggg cttcaaatta tatccgaggg taatttaagc tatcgagtgc
    10261 ctgttatgcg aaatgatgag cttgggaggg ttgcgtttaa tatcaacttg atggcggaac
    10321 gtctacaaca gcagatcgaa aaggaacgtg aactagaaat ctccaagttg gaaatgataa
    10381 caggcatatc acacgacttg cgtacgccac ttacaagcat tattggctat atagaactct
    10441 taagaacaaa ttcatttcaa aataaagatg aatatacgcg atttgttcaa aacacttata
    10501 acaaagctat tcatttaaaa aaattgctcg atgatttgtt tgaatatacc cgacttactt
    10561 cggtcgatac ccgcctggac ctaaataaaa tcgatgtatt ccagcttcta gatcaattaa
    10621 tttttgaatt tgaaccgatc gctcaagaga acggtatcca tattattaaa gacttaggta
    10681 actctcctat tataaccgtt attgacagta aaaaaattgc cagagcaatc gataatctac
    10741 tcatgaatgc ccttaagtac tctgtaaagc caggaaccgt acgtatttta atgaagttgg
    10801 ataataagca aattagtatt gagatcgaaa ataaagggaa tcccctcaca caagagcaag
    10861 aaaataaact cttcaatcgt ttttataaag tagaccattc aagaagtagt gaaggcattc
    10921 aaacgggagc aggtctgggc ctttctattg ctagaaacat tattgagttg catggaggaa
    10981 ccttaacgct cattcatata aataacatat ttaaatttac tcttactttg cctttcgaag
    11041 gagttctgac ccgttccatt ggatcagaag aaggccactc cggcaacctt gatgtataag
    11101 ttaaaaaact taagccccga acaatacttt gtcccgggct taagttttga tttttagtat
    11161 ccaaattaaa cttactctgt tttttaagta taatcttcga gagtgctgac agttaatgtg
    11221 tttatgtaaa acaaaaaagc cgcgcttatc acggccgtac cataattaat gctcatatat
    11281 ttagcctgtt cattatgcag ctcttttctc atctactctc tgaaaacaat atcccgtata
    11341 taatgcttca atgataaatt catttaatgc ctccaacatg tatgcaggtg catccctgtc
    11401 tgctccaaac gtttgcccgc tatcatgaag aacgataaca gctccacccc ttagcttgga
    11461 cagcagcctt tgcttaattt tttgcttgcc gccagagctc ttccagtcac ctacaataac
    11521 agaccaaaga atcatgcgaa attgcttcat cagaaaaaaa tcaaataggt taatgactcc
    11581 ccacgggggc cgataataga aggctttctc tccaataata cgattaatga cattggccgt
    11641 tttgtttacc tgctcgcgaa ccctcttagg actcattaaa gcatttgacc aatgtacata
    11701 attatggatt ccgacaagat gtccttcatt gtgcatccgt tggattaaat cgggatattt
    11761 ctctgctttg cgaccaagga caaaaaaggt accctttata ttatatttct ttaataaatc
    11821 aagcaaaaga ggcgtaaatt ctgggtccgg accgtcatca aaagttaacg caatgggctg
    11881 ctcgcccgtt ccccttttat aaactccgat tccaaatagt cggattataa gggtcgggat
    11941 aatcgtgtat acgagtaatg cactaatgag aattatgaat gtctgcttca tgatcctgct
    12001 cctttttaac agtaataaat ccatgcttgc cttttttcta ggagcatatc tttatttcac
    12061 tggatctatt attcattgca atagttccaa aaataacttc taatgaagca aacgcggact
    12121 ctttaggatg gaactgttta gtattttcta tcatatgttg aagaagtttt gcatcatcta
    12181 gtaattccga taggcgctcg gttagatccc cagatgtctc tcattcaatt tcattcgaag
    12241 tttttcatta tgcccacaaa caatgatgaa ttgtacaggc tgtgacaata gatcaaattt
    12301 ctgaatagta gagcttccat cgccaatcat gccgcaacct cctcccatca caagcacagt
    12361 aggcatatga ggatctaaac catacttctt agctgttttc tctctttcta tggactgaga
    12421 aaattgcggg cgaatgggaa ttcccgtatc tgcaatccga gtctcttcaa cccctaattg
    12481 aattaaagaa tcacgtacac ttctggaacc cacaatatat tgatctgtat atggataaat
    12541 ccatgaacta tgatccgtgt gatcggtaat gatagtaaca gtatgaatat cgattgaacc
    12601 atatgatttc aacttcgaca tcacgcctgc cgccaagggg aaggtgcata ctacaatagc
    12661 tggctgtatt tcattaatca atttcatcat tcgtccgatt cctgtagaaa aaacggtctt
    12721 tataatatag gatagggtgt tttgtctccg cgttttctga tatagatatc cataaacttg
    12781 agggaatgtt tttacggctt ggagataaac atttcgactc aaatgattca tataaggatg
    12841 gacccattcc ataaaatcaa taatgacagg ttccatatga ggaaatcgaa tttgcatcgc
    12901 atcttgtatc gcttgggcta cttgaatgtg accatctcca taatttccgg taagaatcaa
    12961 cattttttct ttcgttcctt ttttcatgga acacagctct ccttttcaaa aaatcaaatc
    13021 tcagaaacgg ttaagaatta ctttccttta tgtcaagaga aatcggcata aactgaaggc
    13081 acagaaagga tgctttcata tgccaaagaa acgattctta ttattgatga tgaaatgaaa
    13141 ttcgggattt ggtgggagta tatctgacta tgacgattta tatttttaaa tcagcatttc
    13201 gccttatgtg aaaatcgttt gagctgctag aatatatagc aacagtgaaa tcataacttt
    13261 gttgtatttc ctttaaatct atcaaaagtg aacttgcgaa ccctcgggca aatcaaaaat
    13321 gtatttaaac atgtgtcggg tcagtttaaa aaaaggggaa aataaaggct ggtctagctt
    13381 tagaaaaaaa tatcccgctt gtaatcgatt tacaaacaaa ttgatgcaag ttattacaat
    13441 ggcgaaactg agatatgcaa tgacgagact gaaaactaac gccaaaaata tctcaaagca
    13501 aacatttctt ttgccgttta tcagtttcaa ttttctaccc aactccccaa acggttttta
    13561 tatatcgcgg ctctcttggg agatcatcta ttttctcgtg taaattcaga atttgaactc
    13621 ctaccgtatt atctaaatct cctaaaggtt gattccacac atcacgcttt gctccttttc
    13681 cgacttttaa gaatcatgaa tatgacaatt cctatgatta aggcaagtcc cacatatata
    13741 ccgtagtgat aaatcattgt cccgattgtt tccacatgac cacctgcaaa ttggccaact
    13801 acaaaaaaga cagacgtcca aacaagaccg gctgtatagg aataaagaat ataacggcga
    13861 aatgacattt tattaattcc gactaaatag ggaacaatat gcctcaccac cggaaaaaag
    13921 tagctaaaac tcaatgcaat atttccatat ttatttagaa ggtgttctga tgtatgtata
    13981 tgcttcccca aatttttttt atggcgaagt ttatccagca ccggcgaacc gaaaaacctg
    14041 cctagaatat aaccaagaga tagcccggag ataactccta aataagtgat aataaatgct
    14101 gggaaatact ggagtaatcc tactttgcta acggctccgc cggtcataac gacaacctcg
    14161 tccggtattg gcattccaac aattccgagc cataatgcaa agaataaagc agcataacca
    14221 aactgcgcaa tccaatgaat tagtgtgtca taactcactt aaatcccctc cttcttacgg
    14281 catgtataaa caaaagcagg aggaaaattg aggggcacaa aatcgatttt atcaatagca
    14341 gatcgattta ctcgcagttc gataaagcgt gtgatagctc ctgtgccaga accgaattct
    14401 gcaattgtgc tcacatcatc ccatgataca gattgaacca ttttactcgc cagaaaccgt
    14461 gaactgggca aaacacttcc aactcgcttt ggatttttaa taaatcgttg caagaacatt
    14521 gcatactgat ttgaagtcaa atgactctcc ccctttcttc tatttttttc atttgttcac
    14581 cagcttatgc agtaaagttg gataatttcg acttgaacca cttggttgtg ataaaggtgc
    14641 caacggctat cattagagca accacggcca atttaggatc gatcaaatct agcaaattca
    14701 atatataatg tccaaggaac ttgccaaagg taaagaacgt agcggtccaa acaaacgcgc
    14761 tggaatacga aatcaaagca aacttcttgt atgaggtacc gtttagacca acgaatacag
    14821 gcaaaatgta ccgaatgact ggtatgaaat gtccaagaca cattgcgaca tctccgtgtt
    14881 gttcaaaaaa tttctctgct ttctgaaagt gacggttgtt ttgaaacttt agtttaaatt
    14941 tttctccaaa gattctgccc gcaaaataag caattgtaat tgctgtaaat aagccagcga
    15001 gaataacaat atatacaatc cacgggttta aagctccgtt gttactcaaa attccacctg
    15061 ttagtatggt tatttcattt ggaaccggga tgccgaatgg gcctaggcag aaggctaaga
    15121 aaaaaaagag atatccataa tgatcgacta gctgtaagac gatatcgcta atcatgttct
    15181 aacctcctcg ttaatgtcga tgaaagtata ttattataaa aatcttagga gcttataggg
    15241 atatttctaa agaaattctg aagtaataca aaaacgcctt taattctccc ctccaagcca
    15301 tggcttgaca tcttaaactg ttttacgccc aatgtaggaa aggtctgatc agcttttaac
    15361 caagctaatc agacctcaac tttatcctaa cactttggta attctacttc tttagcactg
    15421 atggaaattg aaaaagagag agttcactct cctattcccg ctcgtactag tgaaaacata
    15481 gcttcacata caagtagaag aaaatacacg atctcataaa catccccctc cccaacatta
    15541 tgaagggata caaattagag tcacgctagg cctttctata gccataaata tcattgagtt
    15601 gcgtggcgga acagtttgcc cttataaaaa agccttaccg acttggttgg taaggctttt
    15661 tgggttggat gatatagatt ttaaaccttc tatagatgaa tctttagatt ttctttagaa
    15721 atatactcat taattcctta gtttttttca ttatgatttc tgtatcgaaa caataaagag
    15781 gtgcagaaat agaggagatt gggccatgtg catcggtatg ttcttcccaa tcgtacgata
    15841 ttttctccct atgtcttcac ttcaattttc tcatttttaa tcgtttcggt atccatccgt
    15901 ttcgataaaa gaaataaatt tgttaatttt tgtgccatat tcagcattgt tcctgacaat
    15961 aaaaacagta atggaggaaa atcagttgaa acttaatgaa taccttttat ttttgcaaag
    16021 ctttattcac agcccaaaaa atgtaggcag tgttatacca agctctcggt ttctagcgac
    16081 caaaatggtt aaacaagccc cctggaacga aattaaggca gtcgcagaac tcggatcggg
    16141 tacaggtgcc atcacccgct ttatcaacgc ccaggtgagt gaacccacga aagtgttatt
    16201 gtttgagatg aatgagacta tgaggaataa tttacagaca gaatacccag acttctcctg
    16261 tcatccgaac gctgctcagt tagtagaagc aatgaagcaa gagaacattc atcagctaga
    16321 ttgtattttt agcggactac ctttttttaa ttttgagcgt gaattgagag ataccttggt
    16381 tgaacagatc tataaagcac tcaaacctgg aggcttgttt atcgcctttc aatattcgct
    16441 tcaaatgaaa aagcagcttt ccgaaaaatt tatcattgaa aaaattgatt tagcaccttt
    16501 caatatccct cccgctttcg tttacgtctg tcgcaaaaag gaaacaattt aaatgatgct
    16561 ggcactttca ttcactccat taaatgtttc gcttatgcgt atgtagaaaa agtgaagact
    16621 ttaccttatt atcaggatat ctatactagt tgcgtaattt caggtacctt aaataccttt
    16681 attctaccca gtcaaaaaag aaggagcagt cagtaatgaa taccattctt gttgtggatg
    16741 atgattccga gattcgggat gtcattcatg tatatctacg taatgaagga taccatgtga
    16801 ttgaagcagc cgatggtgaa gaagccctgg atgccataaa gacaacaccg attcaactgg
    16861 ttatcttgga tgtcatgatg ccacgaatgg atggaatcag agcatgcctt aaaataaggg
    16921 aaatatcgaa tactccgatt atcatgctgt cagccaagga agaagatatt gataaaatta
    16981 acggactgac taccggggcc gatgactaca tgatcaaacc gttcaatcca ttagaattgc
    17041 ttgctcgtgt aaaagcgcag ctacgtcgtc aaacattaat aggaaaagaa gaatttaatt
    17101 cccttattct tattaaagac ctgatcatcg ataagagtaa acattccgta aagttaaagg
    17161 gcaacgaaat ttcgttgact cctctggagt ttgctattct ggtcttgctt gccagccatc
    17221 ctggacaggt ttttagttcg gagcacattt acgaaaatgt atggaaggcg ccatatggat
    17281 tttctgataa taccgtaatg gttcatattc gtaatttacg agaaaaatta gagcagttcc
    17341 caagagatcc tcagtatatt aaaacggtgt ggggagttgg ctataaaatt gaatgaacat
    17401 gtacaaaagt caaaacgaaa aaaacggatt caagtcaata ttttaatcag aatggtgcta
    17461 agttttatta tcgccattgc tataaatgat attctcattt tacttttctt gaaaattagc
    17521 agtactatgg aatggcattg gtttcgcaat tttttccctt atcttcttac ccccttgttt
    17581 atggtaacgt ttatttttac ttttttagtt ttgacacggc gaatcgttag agacttaatt
    17641 acattggagc aagggcttca gattatttcc gaaggtaatt taaaatatcg ggtacctgtt
    17701 gttcggcaag atgaacttgg acgggttgcg ctcaacatca atcgaatgac agaacgttta
    17761 gagcaacaga ttgtaaaaga acgtgaaata gagaaatcca agatggattt gatcacaggt
    17821 atttcacatg acttgcgcac gcctctgaca agcattatcg gctatatcga gcttttaaga
    17881 acagactcat atcaggataa agatgaatat acgcgctttg ttcaaaacac ctataacaaa
    17941 gcgattcatt tgaagaagtt gctcgatgac ttgttcgaat atactcggct cacttcagtc
    18001 gatacccact taaatctgag aaggatcaat ttatttcaac tcttggatca attgctgttc
    18061 gagttcgaac ccattgctca agaaaacggt gtatatatcg taaaagatat cggtgactcc
    18121 ccagtggtta cctccattga tagcgataaa attgctagag caatcgataa tcttctcatg
    18181 aacgccttaa agtattcctt gaagccggga ggcatttgca ttcgattgaa aacgagtcct
    18241 gagcaaatta cgattgaggt cgaaaataaa ggagctcccc tcacgcaaga tcaagaggag
    18301 aagctatttg atcgttttta taaggttgat cattcaagaa gtagcgaagg tatccaaact
    18361 ggagcaggac tgggtctttc catcgctagg aatattgttg agttacatca aggcacccta
    18421 acgctcaatc atagtcataa cgtatttaca ttccaattga atttaccttt tgtaaacaac
    18481 tcaagtagct aaccgcagtc cttaaagaat atttatacag tggcggatta ttatgatttt
    18541 acatcttaat aaatccattt acagcgactc aggatattcc tatttcataa ccatttcctc
    18601 aatatactga atgtcgcata taacgtgctt aaatgatcaa ttttcttttt caaagaatta
    18661 tctctaataa tctgtccatc tttagtccat tgtccatata tttgaactaa ccgccctgta
    18721 gttcgtgaga gttcaagaag aagtgctgtc ttcagatgct ctttttgaac taaagttagg
    18781 ttattatcca tttttatttt attaaattct tctatcaaat ctcttactag ttcattattc
    18841 acttctttca atgaagccat tgtcttctcc aagagcttca cgtttcctta ttatctcttg
    18901 ataccctgga actaaacata cttcggtttg gacatctttg tactctaatt cagcagattt
    18961 atagattgat tttccgcaaa tagttaaaaa gtagctcaat ttatctaagt ttggtttcgc
    19021 taaattcttt ttcccattaa gttgaccctt gtgaacatag tccttaagtg aatcaattat
    19081 atccaccatt aaaccgataa actcttcctt ctgatcttcc ttaaaatttt tttactctct
    19141 caattaaatt gtcataataa actgacaatt ggttctcgtt cgagatattt gagacaagtg
    19201 tatttataag taacgaaaga tgtgatacgc aacaattagc aataataaga atttataaca
    19261 gtttgaactc ttctgtcatc tagtgaattc aaactatcta ttattggttt aatattagta
    19321 ggtaatggaa caaagtaatc acccccttca tcatattctt cgtaatcgag ttcagttccg
    19381 ttaacgtctt cttttctaat tgttgattct tcctcttcaa tgttataaac cagtttacca
    19441 attgcaggta caggtattat atcctcttcg tctgtaatcg ttctaagttt ataaattcca
    19501 ttatcgtgct ttattacttt tatttgttgt tctaaggctt ccaaggtatc tagtgtcacg
    19561 agagccgcac agtcttcgtg ccatcatacg atattaaaaa acctaatgag gtgagcctat
    19621 tgttcgttca attaaccgtg agtgagataa tgatctgaaa acaaaaaaac tgcacaaaaa
    19681 atatctcgat ggataagcct tgaaaaaaca gcatcatttt atgataaatc taaatgggat
    19741 ttatgcagga aatgcaggat ataaagagag tcttaaaaat ctcaattcag cttattcgac
    19801 cccttttaca aaaaaaacta ccaagcagat ttggatggta gtctgttgtg ttttgtcgat
    19861 tttccaataa attgaaatag ttactcagcg gcacttgacg tcagattcct gtggtggatt
    19921 tttccctttc atttggaaaa aaacacccgg caggatgcgt accgagagaa atacggcata
    19981 cacccaagcc gggtaaggga ttagaaaata atatcaatgg cctctagcac atcttgctcc
    20041 tgttcggatt gcccgttcag ggaaatatcc ttcaacagca ccgaaggctg ttcgcaaatt
    20101 tgggtgatga tcacgagcag gtcctgagcg aaattgtcga tcagattgag cgtaaacaac
    20161 ttggtggcat attcaaactg cccgttcatt ccctcatcca gcaacgaaat gaccaaggta
    20221 agatcaaatt gggaaaccgt atgagtttcc ggataagatt cgatcttgat atccccgaag
    20281 ctttgaacgt tatcttcctt ggtttctaga gcaaacatga catcgaatac aggattgcgg
    20341 ctttgatctc gcggcgcctg cagctttttc acaagctcct cgaacggata atcctggtgg
    20401 tcgtaggccc ccagcatcgt ttctttgact tcgttcaagt aagcgaggaa cgtcttctcc
    20461 ccggacggat aatggcgaat cgccaaagtg ttgacaaaca ttccgatgag cggctccagg
    20521 tcggcatgtg tgcggcccga aaccggcgtg cctacaatga agtcttcttg tcccgagtac
    20581 ttgctgagca ggattgaata ggccgccaat aacaccatat aaagggtggc accgttctca
    20641 tcggcgatgc gctgcaagct gtcggtcatc tgcttgtcga tgctgaaagg cagcacatct
    20701 ccctcaaagc tgcgagcggc aggtctgaca aagtccgtag gcagttcaag cgtcggcagt
    20761 tcgccttcca gcacgtccag ccagtaggct tcctgacgtt tcagccgctc ttttacaggt
    20821 tcggactgct gccaagcggc gaattccttg tattgaatcc gaagcggttc cagagtctcg
    20881 ccgttataca ggcgcagcag ctcttcgacg aagatgccca tcgacatgcc atccgtgacg
    20941 atatgatgaa tgtccagcat gagcagatgt cgttccgctt cccattcgac taagcccaca
    21001 cgcagcagcg gcggccgctc caaatcaaag acgcgtacaa agccgtctac gatgctcttc
    21061 gtttcacttt ccgtcgcttt cgtatactcg acggcaaact tcaagtccgg ataaatccgt
    21121 tgtaccggtt cgccgtcgac catttcgaag ccggttcgca aaatttcgtg acgagctatc
    21181 aatcctttga gcgccgcctc gaattgattc cgttccaagc gcccgacgag aaccgtcatg
    21241 ccggacatgt tgtagctaag ctcggcgcct tccatctgct gctggatgta cagccgtttt
    21301 tgcacggagg aaagcggata gtaatccctc ttatccagaa ccggaatgga gaggtattcc
    21361 tgccgctcca attggctgat cgcttcggcc atcgcttcga tggtcgagtg ccggaacaca
    21421 tcgcgcagcg gcaggtccac cctcagctcc ttgtgcaact tgctgaccag cgtcgtcgcc
    21481 cgcagggagt gcccgccgag gtcgaagaag ttgtccgtca cgccaatcgt gaccggcccg
    21541 agcacgtcct gccagatggc gaccagtttc gcctccagtt cggtgcgcgg cgccacgtat
    21601 tcgcggcctg cgcttgctcc cccttccggc gccggcagcg ccttccggtc gattttcccg
    21661 ttcggcgtca gaggcaggcg ctccagctcc acgaagtacg acgggatcat gtaacccggc
    21721 agctcgctgg agatcgcccg tttcaggtcc gccgccgtca agccttcttc cgctgtataa
    21781 taagcgcaca aagctttctg accttcttga tcttccctga cgacgacgac cgcttccttc
    21841 acgccaccta cactcagcag cttcgcttcg acttcgcccg tctcaatccg gtacccccgg
    21901 attttcgcct ggttgtcgat ccggccgatg aagtccacgt tgccgtcttc catccaccgc
    21961 gccaagtctc ccgtgcggta cagccgctcg cccgcggcga acgggctgtc tacgaacttc
    22021 tcttctgtca gctccggacg gttcaagtac ccgcgcgcta ccccgactcc gccgatgacc
    22081 agctcgccca gcaccccgac cggcaccgga ttcagatgcg catccacgat gtagaatttc
    22141 gcattcagcc acgctttgcc gatcggcaca tggcctgtct gcggcagctt cgccagctcc
    22201 tcgtcgtaga agcttgagtc gatcgccgct tccgtcacgc cgtatgcgtt gatgatccgg
    22261 aacaacgagc c
//
