LOCUS       NZ_FOYL01000010        22043 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea waywayandensis strain DSM 44232, whole genome shotgun
            sequence.
ACCESSION   NZ_FOYL01000010
VERSION     NZ_FOYL01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea waywayandensis
  ORGANISM  Lentzea waywayandensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900115955.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:54:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,449
            CDSs (total)                      :: 9,363
            Genes (coding)                    :: 9,244
            CDSs (with protein)               :: 9,244
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 26 of 119
            Pseudo Genes (incomplete)         :: 101 of 119
            Pseudo Genes (internal stop)      :: 5 of 119
            Pseudo Genes (multiple problems)  :: 12 of 119
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:39:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 308313
            Orig. end                         :: 330356
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOYL01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22043
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22043
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22043
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12043](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12043
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            464..1684
                     /locus_tag="BM417_RS32975"
                     /old_locus_tag="SAMN04488564_110290"
     CDS             464..1684
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466189.1"
                     /locus_tag="BM417_RS32975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110290"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_093602611.1"
                     /transl_table=11
                     /translation="MPEAVIVSAARSPIGRAGKGSLKDVRPDDLVARMIRAALDKVPQL
                     DPAQIDDLMLGCGLPGGEQGFNMARVVSVLLGYDNLPGTTVTRYCASSLQTTRMALHAI
                     KAGEGDVFISAGVEAVSRFAKGSSDSWPDTHNPLFGEAEARTASVAASGASEWVDPRSV
                     DVVPDVYIPMGQTAENLALLRGISRQEMDEFGVRSQNLAEKAIADGFWAREITPVTLPD
                     GTVVSSDDGPRAGVTYEAVSQLKPVFRPDGRINAGNCCPLNDGAAALVIMSDTKARELG
                     ITPLARIVSTGVSGLSPEIMGLGPVEASKRALALAGLSVSDIDLVEINEAFAAQVIPSY
                     QDLGIELDRLNVNGGAIAVGHPFGMTGARITTTLINSLQFHDKQFGLETMCVGGGQGMA
                     MVIERLS"
     gene            1848..2057
                     /locus_tag="BM417_RS32980"
                     /old_locus_tag="SAMN04488564_110291"
     CDS             1848..2057
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS32980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_110291"
                     /product="hypothetical protein"
                     /protein_id="WP_143138892.1"
                     /transl_table=11
                     /translation="MPYVWWQSEYDLQCHAFSLDQTDGSRSFYEAVCEHSVPDERVSRA
                     QAGALCTTCLIKVGTELPDVRWRV"
     misc_feature    complement(1851..1865)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.95"
                     /tool="antismash"
     gene            complement(2054..2464)
                     /locus_tag="BM417_RS32985"
                     /old_locus_tag="SAMN04488564_110292"
     CDS             complement(2054..2464)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015802092.1"
                     /locus_tag="BM417_RS32985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110292"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_093602615.1"
                     /transl_table=11
                     /translation="MDSAYRLVLEPPSVDDYLRLRKESGLSARTREEAENGINGAWASA
                     SVIHVESGESVGMGRVLSDGGWYFHVIDMAVLPDHQRKGVGDAILTALLDHIDACAPNA
                     YVNLLADPPGRRLYERHGFTESAPASVGMRRV"
     gene            complement(2476..2808)
                     /locus_tag="BM417_RS32990"
                     /old_locus_tag="SAMN04488564_110293"
     CDS             complement(2476..2808)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025030.5"
                     /locus_tag="BM417_RS32990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110293"
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_093602617.1"
                     /transl_table=11
                     /translation="MTKRFDEGMRLLRRKGEDRENGFCLLQRHAVELLDELIEAFRGEE
                     AENMRVLLLTLIGEARSPRALPILAEHLDHEDESLAYWAVRGLEMLDTKEARTVLYRHR
                     ANNAHT"
     gene            complement(2878..3684)
                     /locus_tag="BM417_RS32995"
                     /old_locus_tag="SAMN04488564_110294"
     CDS             complement(2878..3684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155843.1"
                     /locus_tag="BM417_RS32995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110294"
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="WP_093602619.1"
                     /transl_table=11
                     /translation="MRSSSNPAFRNLPTGGGYGGYAGFGQPDQAGYQQAPPPLTSERPM
                     TIDDVVTKTGITLAVVAATAVVTYLMQAWFLLFPAAIVGLVLALIIMFKRMPSPPLVIA
                     YAAVEGVFLGAFSGIIGNMVDRMTGNPGQGVVMIGQAIIGTLGVFFGMLVVYKTGAIRV
                     TPKFTKWITGAIIGVAVLMLFNLIMSFFTAGGLGLRNGGTLAIIFSLVCIGLAAFSFLI
                     DFDAADQAIRAGVPAKFAWQIAFGLTVTLVWLYTEILRLLSYFNSD"
     misc_feature    complement(3826..3841)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     misc_feature    3864..3879
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.05"
                     /tool="antismash"
     gene            4005..5393
                     /locus_tag="BM417_RS33000"
                     /old_locus_tag="SAMN04488564_110295"
     CDS             4005..5393
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098213.1"
                     /locus_tag="BM417_RS33000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110295"
                     /product="collagen binding domain-containing protein"
                     /protein_id="WP_093602621.1"
                     /transl_table=11
                     /translation="MGWKRLAAVAMVSGLALLTVPATASAIGVKGIGHNASGLQPNATP
                     GSEWHGSYVWQDKQVWCVQYALPAPDSNVGYKEGDALRTKAGKDLAPDVAANISYLLLR
                     YSTTKSPEEAAALAHLLHSWTSAPDGAVRFDTTDAKYLAYDASFYAARLPQSVMDTVAR
                     IKADAEANRGPWTLTATAPKEPLIIDTESTWTLSLIKANEKGVTNAPIAFTLTDAKLAD
                     GKTSGTATTGADGQPAAVKVIPTGPKPSIAAVADSPADRPVVHFPIQTDNMQRMVTTGG
                     EKKLNAAANGQAKTAPGAVKITKIDSETKKAIAGVALRVTAKDQTTAAKKQDDTDLVGT
                     DGKPLVLQTGPDGTVEVPDLRTPQEICLVEVAAPKGYEEFFDPKAPPASCGTVAAGQTL
                     ALELVNKPNKPVVPSTIPAGADGQTPVATASFDTQLSPGLMLTAGGLVLLGAALAGFLV
                     WRRQ"
     gene            5378..6088
                     /locus_tag="BM417_RS33005"
                     /old_locus_tag="SAMN04488564_110296"
     CDS             5378..6088
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683244.1"
                     /locus_tag="BM417_RS33005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110296"
                     /product="class F sortase"
                     /protein_id="WP_177320720.1"
                     /transl_table=11
                     /translation="MAQAVSPKAFLTGTLVAGIAAASVLVTTSETEVLKGHAVADEIPV
                     VGPGPVADSLSTGRGPDLTGLLGGANTANARPADPTPQQQQPAPPKAGPGSVRLPSGGS
                     ATLVRKEVKDGVLPVPDGIGEATWWGTELAGAEGATVLAGHVDWKGAKGPFAELWQAQN
                     GREVVIADSAGKEFKFRIRQIETVRKEELPARAVEFFGPRGPHRLVLVTCGGTWVGGQQ
                     GYEANRVVIAEPVQ"
     gene            6159..7310
                     /locus_tag="BM417_RS33010"
                     /old_locus_tag="SAMN04488564_110297"
     CDS             6159..7310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013676747.1"
                     /locus_tag="BM417_RS33010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110297"
                     /product="polysaccharide deacetylase"
                     /protein_id="WP_245822311.1"
                     /transl_table=11
                     /translation="MTTGVALGLVLAIVMTLGSHKEQTSQADSGPLPMAPRLPAPKDAG
                     PTPTVPAPSAEQLQKQPWMHKLAPGEKPPQFVLFSFDGAVSKQHWDKVLPIAKSKNAHV
                     TGLLSGVYMLADPDKNQYQPPAGLKRGLSDIDFGGTRQDVNSRIAYLNQVIADGHEIGT
                     HYNGHFCSNGTQPSVDKWDTAAWNAELAQFKQIVDRSRAAGLNLPADAVRGGRTPCLEG
                     NWDQAFPAMAANGLVYDTSKVALGVQWPTVQNGLYEFPMPEVKVPGLGKQVVMMDFNLW
                     YSLNQAKDEPSRAADFSQIVLDTYKSVHQAALNGNRAPIVVGNHFNEWNGNAFSTAMEQ
                     FMEYVCDKPDTVCATYTEVIQWMQLQDPAVLDQLRRMPAARNW"
     gene            complement(7311..8345)
                     /locus_tag="BM417_RS33015"
                     /old_locus_tag="SAMN04488564_110298"
     CDS             complement(7311..8345)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098210.1"
                     /locus_tag="BM417_RS33015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110298"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_093602625.1"
                     /transl_table=11
                     /translation="MRARRIAAVAACTAVAASLCALPASAQDGPSVLAERTLATKLHIP
                     WDIEFLPDGSGIFTERDTKKIKKIKGTTVTDLDTVEQAQTTGGEGGLLGLAVSKSFATD
                     NSVFIYYSTASDNRVAKLQLGGTPQPIVTGIPKNRYHNGGGLEWGPDGFLWATTGDGQN
                     TANAQNWNSLGGKVLRFDATGKPAAGNPRAGSVVYSIGHRNVQGITWIGSTAYATEFGN
                     NTTDEINRIEAGKNYGWPTCEGNCNTAGMTNPVKTWSTSQAGPTGIAFYKNALYVGAVT
                     GKRVWKIPVNGTTLGTPQAVFTGYGRVRAVTTAPDGTLWIGTSNRDANGSPGANDDRII
                     STDG"
     gene            complement(8525..9520)
                     /locus_tag="BM417_RS33020"
                     /old_locus_tag="SAMN04488564_110299"
     CDS             complement(8525..9520)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033796.1"
                     /locus_tag="BM417_RS33020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110299"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_177320721.1"
                     /transl_table=11
                     /translation="MGARRSAHIGVLALAVGLSSAPLASAATPDDVGAMAVKTIASGLS
                     QAWSIDFLPDGTGVFTQKDAKTVSTITKEGKVTKVGDIPGVSVTKEAGLLGIAVSPTYA
                     ADKTLFLYYTTGSDNRIATWQIGGGAPKPIVTGIPRGSQYHHGGRIKFGPDGFLYAGTG
                     DGQNGNNAQNKNSLGGKVLRMTKDGKAAPGNPFGSLVYSYGHRNVQGLTWVGTQLYVSD
                     IGASKVDELNRIDAGKNYGWPTCEGSCSTSGMTNPVKQWPTSQATPSGLTTYKGSLYMA
                     SLKGGTFKLNTSGAGGKIYTNLGRTRDEVAGPDGSLWVITPGGIHLADGN"
     misc_feature    complement(9734..9745)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            9791..9913
                     /gene="pqqA"
                     /locus_tag="BM417_RS33025"
                     /old_locus_tag="SAMN04488564_110300"
     CDS             9791..9913
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005464294.1"
                     /locus_tag="BM417_RS33025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110300"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_063758378.1"
                     /transl_table=11
                     /translation="MNVAVTTTETKLPEVRREWVKPDFRDFETPMEVTAYAARS"
     gene            10001..10696
                     /gene="pqqC"
                     /locus_tag="BM417_RS33030"
                     /old_locus_tag="SAMN04488564_110301"
     CDS             10001..10696
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005150533.1"
                     /locus_tag="BM417_RS33030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110301"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_093602629.1"
                     /sec_met_domain="TIGR02111 (E-value: 1.2e-84, bitscore:
                     277.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVSPAEFVAELRALAPRYWDSHPFHLRMHAGQLSKHELQAWAA
                     NRWYYQRCIAQKDAAILSNCPSPEIRRQWRERIVWHDGTQPGEGGAENWIRLAEAVGLT
                     REEVLDERHVLPGTRFAVDAYVNFARTKPWVEAIASGLTEMFSGALMRKRLAALREQYP
                     WIAEEGFAYFTNRIQAVAGEGQATVDIVVAHSLTREQQLAAVDALSFKCDVLRAVLDAV
                     DYYSGKGRP"
     gene            10693..10971
                     /gene="pqqD"
                     /locus_tag="BM417_RS33035"
                     /old_locus_tag="SAMN04488564_110302"
     CDS             10693..10971
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098207.1"
                     /locus_tag="BM417_RS33035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110302"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_245822312.1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.1e-21, bitscore:
                     69.5, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.2e-13, bitscore: 43.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAVALDAVPRIRRGVKCAYDQIREAHVVLFPEGVLVLNETAAS
                     VVALCDGVRSVGDIAVVLADEYDGVEPEDVAELVARMVERRVVDVDG"
     aSDomain        10702..10959
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BM417_RS33035_PqqD_RRE.1"
                     /evalue="2.30E-22"
                     /identifier="RREFam006.1"
                     /label="BM417_RS33035"
                     /locus_tag="BM417_RS33035"
                     /protein_end="89"
                     /protein_start="3"
                     /score="69.5"
                     /tool="antismash"
                     /translation="AVALDAVPRIRRGVKCAYDQIREAHVVLFPEGVLVLNETAASVVA
                     LCDGVRSVGDIAVVLADEYDGVEPEDVAELVARMVERRVVD"
     gene            10964..12043
                     /gene="pqqE"
                     /locus_tag="BM417_RS33040"
                     /old_locus_tag="SAMN04488564_110303"
     CDS             10964..12043
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005150538.1"
                     /locus_tag="BM417_RS33040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110303"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_093602631.1"
                     /sec_met_domain="PTHR43273 (E-value: 3.1e-32, bitscore:
                     106.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-24, bitscore: 81.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 8.3e-14, bitscore: 46.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.6e-13, bitscore:
                     43.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAPFGLLAELTHRCPLQCGYCSNPLELVRRDAELSTEDWRRVF
                     DQARALGCLQIHLSGGEPLLRPDLPELVAHANSLGCYVNLVTSGVGLSRDRLRELASLG
                     VDHVQLSLQDATKEGNDRIAGIKAFDRKVEAAAHVLDEGLPLTVNTVLHRQNLDNIAGI
                     IAMAEQMGAERLELANTQYYGWALRNRAVLLPTRAQLAIADPIVAAAQERLRGRMEIVY
                     VIADYHEAHPKPCMYGWGARQLTVAPNGDVLPCPAATVISSLTIENVRDSSLHEIWHDS
                     PSFNAFRGFEWMQDPCRSCPRKEIDFGGCRCQAFQLTGDAAATDPVCSLSPERSTVDLI
                     LETEMAPAEVPAMAMRKMR"
     gene            12040..12921
                     /gene="pqqB"
                     /locus_tag="BM417_RS33045"
                     /old_locus_tag="SAMN04488564_110304"
     CDS             12040..12921
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631257.1"
                     /locus_tag="BM417_RS33045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110304"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_093602633.1"
                     /transl_table=11
                     /translation="MKAVLLGTTAGGGFPQWNCACALCVRARSGSLPSRSQDCLAISGN
                     GTDWWLVNASPDIRTQIASCSFLNPGPGARDTPLRGALFTDAELDHTLGLLTLRGGAGL
                     TVWAPGPVLHALQDQFDLRTVIDGYAPVAWRQVEADQSFSISGLRVSAIPISGKRPKYA
                     RSSTVDGHWVVAYRFEDPVSGGVLVYAPCLASWPSGFDEVVAGADCVLLDGTFYAASEM
                     GSATGSSSGQAAMGHLPISASLPELRRFPSVRRLYTHLNNTNPVLDPSSPEFSKVREAG
                     VEVPLDGTVIEL"
     gene            12940..14085
                     /locus_tag="BM417_RS33050"
                     /old_locus_tag="SAMN04488564_110305"
     CDS             12940..14085
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030324.1"
                     /locus_tag="BM417_RS33050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110305"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_093602635.1"
                     /transl_table=11
                     /translation="MSYVIGGRPLADRLVAEMPSFVRQVIASLVQRVPAYAQLPAEELD
                     GDIFRVTEHALRGFAAVLATGSLPSADELRFLRESAARRAEEGVPIDVVLTAYHVGIQV
                     VWETLVPEARPEEVSDVLALNALALRYLQLVTPVVSAGYLDERQTMFDDERSARATLLT
                     GLLSGTVEASGPYVVLALHIPPHPDELLDGVDAAVAGRRKLRRLRTELERHSREPVLSS
                     LTPEGGLALLPGEDPPLERIVADVTRSAGTPVTVAAVAASPSEVAAAAVLAREVLAVAV
                     RSGPGLYRLADVLLEYQLSRPSAALRPLASIVEPLTEELVQTLEVYLRRGSRRPAASEL
                     HVHPNTVDYRLRRVAELTGLDPTRIEHVTLLAAALAARRAR"
     gene            complement(14126..14968)
                     /locus_tag="BM417_RS33055"
                     /old_locus_tag="SAMN04488564_110306"
     CDS             complement(14126..14968)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640311.1"
                     /locus_tag="BM417_RS33055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110306"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_177320722.1"
                     /transl_table=11
                     /translation="MRIVAGLAVVAMLVAGTSTAQADSLDYVALGDSAAAGPLIPNQDP
                     ALWCLRSDRNYPQVAAKVLGARLTDVTCSGAKTDDFGGRQFGFVAPQYDALKPTTDLVS
                     LTIGANDIGLFQTALSCVNLLPEPVGVSCHDRYNAGGTDQLAQAVDAWAPEFGAALDEI
                     KRRSPNARLLVTGYGTYIRPGGCYPRQPVWGRDGDYLQSVMNRISATAKAEAAKRGATF
                     VDFAAVTVGHDICAAPADRYLEGLIPTTIAAPLHPNAAGMKAFGTAVAKATDLVGPAA"
     gene            15086..15826
                     /locus_tag="BM417_RS33060"
                     /old_locus_tag="SAMN04488564_110307"
     CDS             15086..15826
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012673.5"
                     /locus_tag="BM417_RS33060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110307"
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_218164637.1"
                     /transl_table=11
                     /translation="MTPGELLTLAAQSCVDAAKLLHDVRVDVSPKGTFDQVSTADLEVE
                     AFLRAALVSGAPGSAVVGEELGSSSAPLTWYVDPIDGTRNFVRGIPLSCISVAAAVEGT
                     LVAGCVLDPFRDELFTAAVGVPFRVRSSGLSIPPGTSPRPLVLTDIPLPGSPHQGEMEL
                     LNDLLDVADVRRVYSTALSLAWVATGRADAAANIGIHPWDVAAGAVLVREAGGEFREIG
                     SNGFVAGRGEIVGWLAQRMEGIVS"
     gene            15823..16506
                     /locus_tag="BM417_RS33065"
                     /old_locus_tag="SAMN04488564_110308"
     CDS             15823..16506
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (25-144). E-value: 8e-07. Score:
                     21.1. Matches aSDomain:
                     nrpspksdomains_BM417_RS33065_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034196.1"
                     /locus_tag="BM417_RS33065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110308"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_093602639.1"
                     /transl_table=11
                     /translation="MIDLSGRVVLVTGTDGPIGNGIALRFEAAGAQVVRHRGVGDGDLR
                     TSAKRVVDDAFARHGRLDAVVNNAGVQPVEPLPDMTSAQWQFVVDTNLTAPFAVTQAAA
                     AHLPEGGSVTHIASIEGTSPAPGHAHYAASKAGLIMHARAAALEYGSRGIRVNTVSPGL
                     ITRPGIEEQWPEGVARWRAAAPLTRLGTPEDVGDACVFLASDLARWITGHDLVVDGGVT
                     ARPTW"
     aSDomain        15898..16254
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS33065_PKS_KR.1"
                     /evalue="8.00E-07"
                     /label="BM417_RS33065_PKS_KR.1"
                     /locus_tag="BM417_RS33065"
                     /protein_end="144"
                     /protein_start="25"
                     /score="21.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="FEAAGAQVVRHRGVGDGDLRTSAKRVVDDAFARHGRLDAVVNNAG
                     VQPVEPLPDMTSAQWQFVVDTNLTAPFAVTQAAAAHLPEGGSVTHIASIEGTSPAPGHA
                     HYAASKAGLIMHARA"
     gene            16801..17850
                     /locus_tag="BM417_RS33070"
                     /old_locus_tag="SAMN04488564_110309"
     CDS             16801..17850
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS33070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_110309"
                     /product="YncE family protein"
                     /protein_id="WP_143138893.1"
                     /transl_table=11
                     /translation="MTSGNRAVSRRTLLTAALGGAAVGVVGHSLFAGAANAAPAAGRKK
                     LLIGSVDPLGNGIVQLTDPSLTGEQTIVAVNGQPNGIVGSPDGLRAYVGTVFGPGLSVV
                     DVDGGRVTSEVAVGGFVNELVVSPDGKTVYVATGSSGAGGSRGHVAVVDTATGKVRALI
                     NAGLLPRTLALTPDGTQLFVGDERAKGITIIDTAKNAVSGSFKTEKSPLQLAIDPKGKS
                     LYVASSRELITFDLRGGKSGSTELEGVPCGLAVHPNGTFAVVSLYTGRATDSQLVTVNI
                     NSNKVRTKEGNGKANGPLAMSKDGARAFVLDKKNRKVISADTDSGKPDSSLSTPNSNTP
                     TSVAFVETA"
     gene            17870..19237
                     /locus_tag="BM417_RS33075"
                     /old_locus_tag="SAMN04488564_110310"
     CDS             17870..19237
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS33075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_110310"
                     /product="hypothetical protein"
                     /protein_id="WP_093602643.1"
                     /transl_table=11
                     /translation="MPISMSVKTLDYTPAYPPYPSLWMAGYGGAPRGNQGLVDRRLRAQ
                     CIVIDDGAGPKVMLRVDVVSIPRYVHQAIRSGVTPMVDDHDGNFLIICSHTHSGPFIGT
                     TRPNPYVMMSLTPADVSAIEDTTNVFIAQMIELVEQTLAMARTQVTLWYKEGNASIGYN
                     RAGEPNDLSTVNALIARRTSDNGLHTVLFGYACHAVARGNDRYFCSDFPGAATDVISNA
                     LGVQALFFQGAAGDQEPNDPHGPGQVTNLGTILGNEVVAMVNSGGWTAVTGPISTYYEE
                     LSLPLTVDLGDPAAVIRARNSYSDRLDNLPPSDFAYRHAEVMLEEIAGVGLPRVFPMPI
                     QRWKMGGLNIFAMSHEVLSEYAVKLRNQTPGKLWVMAYANETEGYVAANGILQDGGAVR
                     WGYEAGWVDNPDISGEATWTTFYPWPAPLKFSPSGPAAPGTTERVVLDASTAMLNL"
     gene            19254..20114
                     /locus_tag="BM417_RS33080"
                     /old_locus_tag="SAMN04488564_110311"
     CDS             19254..20114
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025870.5"
                     /locus_tag="BM417_RS33080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110311"
                     /product="tachylectin-related carbohydrate-binding protein"
                     /protein_id="WP_093602645.1"
                     /transl_table=11
                     /translation="MPGPSTTLSARYGLTPVYPCGTTGDLFLFEHMTPTTGTFAWGQSY
                     QVGAGWQGRVLAGPSGWMFSITTTGELRLLHYNGTNWDDLDGSQYRVLGQGWSYTAANT
                     RNRISVDEDGVLYTLDAAGNLKAHYFNFTTQQWAVQGALLATGLTQYNAIVATSRGVVY
                     ARNAAGAMYRYYINFWSGATATWFTPASPVTTGWQNLKNLSSAGGEAFYAVNQNNGNLL
                     WYSYNPVTNAWKNAKIIGSGWSNEQDVVVQSNACSRFPWDTACNSFGMQDGGAVITRLN
                     QVKKN"
     tRNA            complement(20335..20411)
                     /anticodon=(pos:complement(328688..328690),aa:Leu,seq:taa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BM417_RS33085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN04488564_110312"
                     /product="tRNA-Leu"
     gene            complement(20335..20411)
                     /locus_tag="BM417_RS33085"
                     /old_locus_tag="SAMN04488564_110312"
     gene            complement(20530..21636)
                     /locus_tag="BM417_RS33090"
                     /old_locus_tag="SAMN04488564_110313"
     CDS             complement(20530..21636)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098200.1"
                     /locus_tag="BM417_RS33090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_110313"
                     /product="hypothetical protein"
                     /protein_id="WP_245822313.1"
                     /transl_table=11
                     /translation="MSRSADGRVPGAPSEAARPLLLQGQEYLFRSPPKCLDFQEQVHRL
                     GMVDEGDGNPQPCVLVLARAADMEMNELSIALAERGIRMARIDADRCVDLPLSVYTDQP
                     LIELDRWLLRPLLVWRRHFELSAVPVEPGTLAGAYAVDQWASVANWLSSRSDWAHVNPS
                     RFSTHLDRLTQLSDASAFGLRVPRTAVTTRPGRTRPGGGACIVKTAGRHLLEPRPGVQH
                     GLFPRPLETSRASDAPEPAPVIVQEYVPSDTELRVFVVGERCIAYQVDKLDPAQLWVDP
                     DAVRVTPTSVPASLSDRLFALARHWRVQVAAFDLLVTGSGDHVFLEINVNCDWRWFEHR
                     AGDNSVSAAVHDWVALRFKELLGAGRAR"
     gene            complement(21633..21755)
                     /locus_tag="BM417_RS49940"
                     /old_locus_tag="SAMN04488564_110314"
     CDS             complement(21633..21755)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS49940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_110314"
                     /product="hypothetical protein"
                     /protein_id="WP_256238980.1"
                     /transl_table=11
                     /translation="MSLEELAAQLRRGEIEDPALAQYAAEYAQAGQVFRSKKDD"
     misc_feature    21850..21866
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     misc_feature    complement(21939..21952)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.83"
                     /tool="antismash"
     misc_feature    21949..21963
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.68"
                     /tool="antismash"
ORIGIN
        1 ggcacgtgcc ccgacctcgg gatcgtgcgg ccgattcccc agccgttgcg gatggtcggg
       61 catcagtaca gcctgcgtct cgcggcggcg cagaccgccg cggtgcgagc ggccggtggc
      121 gtgccggtgt cgttggcgaa tctgctggcg ccggagttca tggctcggca cgccgacatg
      181 ttcagctcgg accgctttca ccccagttcc gtcggctacg aggcggcggc gggcgtgctg
      241 ctggcgccgt tgtgccaggt agcggggctg tggccgggct gggtcgctcc cgctctgccg
      301 ttgcggtcgg cggccgcgct ggcggtgcgc ccctctcgcg tgccggggtg gctgcagaag
      361 cggcacgcct gagtttcgga attctcgtca ctcgcgctgg ccggggtgag cgggcgttaa
      421 ctaggctcga cggcaacctt gactctcaac gaggagtttc gtgatgcctg aggccgtgat
      481 cgtctccgcc gcccgttccc ccatcggacg tgcgggcaag ggctcgctga aggacgtgcg
      541 gcccgacgac ctggtggcgc ggatgattcg cgcggcactg gacaaggtgc cgcagctcga
      601 ccccgcgcag atcgacgacc tgatgctcgg ctgcggcctg cccggcggcg agcagggctt
      661 caacatggcg cgcgtcgtgt ccgtgctgct gggctacgac aacctgcccg gcacgaccgt
      721 gacccggtac tgcgcctcgt ccttgcagac cacgcgcatg gcgctgcacg ccatcaaggc
      781 gggcgagggc gacgtgttca tcagcgccgg cgtcgaggcc gtgtcgcggt tcgccaaggg
      841 cagctccgac tcgtggccgg acacccacaa cccgctgttc ggcgaggccg aggcgcgcac
      901 cgcctccgtt gccgcgtccg gcgcttccga gtgggtcgac ccgcgttcgg tggacgtcgt
      961 gccggacgtc tacatcccga tgggccagac cgccgagaac ctcgctctgc tcagggggat
     1021 ctcgcgccag gagatggacg agttcggcgt ccgctcgcag aacctcgccg agaaggccat
     1081 cgcggacggc ttctgggccc gcgagatcac gcccgtgacg ttgcccgacg gcaccgtggt
     1141 ctcgtccgac gacggcccgc gcgccggcgt cacctacgag gcggtttccc agctgaagcc
     1201 cgtcttccgc cccgacggcc gcatcaacgc cggcaactgc tgcccgctga acgacggcgc
     1261 cgcggccctc gtgatcatgt ccgacacgaa ggcccgcgaa ctcggcatca cgccgctcgc
     1321 ccggatcgtg tcgaccggcg tctcgggcct gtcgcccgag atcatgggcc tcggcccggt
     1381 cgaggcctcg aagcgcgcgc tggcgctggc cggcctgtcg gtctccgaca tcgacctcgt
     1441 ggagatcaac gaggcgttcg ccgcccaggt gattccgtcc taccaggacc tcggaatcga
     1501 actggaccgg ttgaacgtga atggtggcgc catcgccgtc ggtcacccgt tcggcatgac
     1561 cggcgcccgc atcaccacga ccttgatcaa ttcgctgcag ttccacgaca agcagttcgg
     1621 tctcgagacc atgtgcgtgg gcggtggcca gggcatggcg atggtcatcg agcggctgag
     1681 ctgacctttc gctcaagatc tgcaaattga cgcctgcaag tagctccgct tcacccgaac
     1741 ggagctactc gcaggcaccc tttctgccga tgagatgaaa catcgcgcaa tggcgtcatc
     1801 tggcgagggg aagtccgtcc ctaccgatga gtaaggaggg gtcggacatg ccctacgtgt
     1861 ggtggcaaag cgaatacgac ctgcaatgcc atgctttctc cctcgaccag accgacggct
     1921 cgcgcagctt ttacgaggcc gtctgcgaac attcggtgcc cgacgaacgg gtgtcacgcg
     1981 cccaagcggg cgcgctctgc acgacctgcc tgatcaaggt gggaaccgaa ctgcccgacg
     2041 tccgctggcg ggtctagacc cgcctcatgc cgacactcgc cggtgcgctc tcggtgaagc
     2101 cgtgccgttc gtagagacga cggccgggcg ggtcggccag gagattgacg tacgcgttcg
     2161 gcgcacaggc gtcgatgtgg tccagcaacg cggtgaggat cgcatcgccg acgcctttgc
     2221 gttgatgatc cggcagcacc gccatgtcga tgacgtggaa gtaccagccg ccgtcactga
     2281 gcacacgccc catgccgacg ctttcgcctg attccacgtg aatgacactg gcgctggccc
     2341 acgcgccgtt gatgccgttt tcggcttctt cgcgagttcg cgcgctcagt ccggattcct
     2401 tgcgcaggcg caggtagtcg tcgaccgatg gcggctccag gacgagccga tatgcggagt
     2461 ccactgaatt ccccctcacg tgtgcgcgtt gttggcacgg tgacggtaaa ggacagttcg
     2521 cgcttccttg gtgtcgagca tctcgagacc acggacagcc cagtacgcga gtgactcgtc
     2581 ctcgtggtcc aggtgctcgg ccaggatcgg cagggctcgc ggcgaccggg cctcaccgat
     2641 cagcgtgagc agcagaacgc gcatgttctc ggcctcttcg cccctgaacg cctcgatcaa
     2701 ctcgtcgagg agctccacgg catgccgttg cagcaggcag aagccgttct cccggtcctc
     2761 gcccttgcgg cgcagcaacc gcattccctc gtcgaacctc ttcgtcatcc catctccccc
     2821 agaacggcga aggggcgccc cgccgcagcg gaacgcccct tcaactcacc cgaaacgtca
     2881 gtccgagttg aagtacgaca gcaggcgcag gatctcggtg tacagccaca ccagggtcac
     2941 ggtgaggccg aacgcgatct gccacgcgaa cttggccggc acgccggcgc ggatcgcctg
     3001 gtccgcggcg tcgaagtcga tcaggaagct gaacgccgcg aggccgatgc agacgaggct
     3061 gaagatgatc gcgagcgtgc caccgttgcg caggccgagg ccgccggcgg tgaagaagct
     3121 catgatcagg ttgaagagca tgaggacggc gacgccgatg atggcgccgg tgatccactt
     3181 ggtgaacttc ggcgtgactc ggatcgcgcc cgtcttgtag accacgagca tgccgaagaa
     3241 cacgccgagc gtgccgatga tggcctggcc gatcatcacg acaccctgac ccgggttgcc
     3301 ggtcatgcgg tcgaccatgt tgccgatgat cccgctgaac gcgccgagga agacaccttc
     3361 gacggcggcg taggcgatga cgagcggcgg gctcggcatg cgcttgaaca tgatgatcag
     3421 cgcgagcacg aggccgacga tcgcggccgg gaacagcagg aaccacgcct gcatgaggta
     3481 ggtgacgacc gcggtggcgg ccaccacggc gagcgtgatg cccgtcttgg tgacgacgtc
     3541 gtcgatcgtc atcggccgct cgctggtcag cggcggcgga gcctgctggt agccagcctg
     3601 gtctggctgg ccgaagcctg cgtagcctcc gtacccgccg ccggtcggca ggttacggaa
     3661 agccgggttg ctgctcgagc gcacctggtc ctcctgtggc gttgctttac gccgtcactg
     3721 ggttcaacga gcacgctcgg tgccatgttc cccatcggta aaggcgactt tacccccgac
     3781 gacgatcaca cgtgcgcaaa tactgcgcca actccagagc gttatgtgac tacggcgtgt
     3841 cgcggcgtgt cccgcacgaa gggcgtaagc cccgtcacat tccaatcacg ttcacaccca
     3901 gagtagcgag agacttcccc ctcgtggcgg cttgtccccg gtgtggggga ccgacaagct
     3961 cgcacgcggg ataatccgca ggtcagaggg gatcaagatc caaaatgggc tggaaacgtc
     4021 tggccgccgt ggcgatggtt tcggggctcg cgctcctgac cgttcccgcg acggcgtcag
     4081 cgatcggcgt caagggcatc ggccacaacg cgtcagggct ccagcccaac gccacaccgg
     4141 gcagtgagtg gcacgggtca tacgtctggc aggacaagca ggtgtggtgc gtgcagtacg
     4201 cactgcccgc gccggacagc aacgtcggtt acaaggaagg cgacgcgctg cgcaccaagg
     4261 cgggcaagga cctcgccccg gacgtcgcgg cgaacatctc ctacctgctg ctgcgctact
     4321 ccacgaccaa gtcgccggag gaggccgccg cgctcgcaca cctgttgcac agctggactt
     4381 cggcgcccga cggcgcggtg cggttcgaca cgactgacgc gaagtacctc gcctacgacg
     4441 cgtcgttcta cgccgcgcgg ctgccgcagt ccgtcatgga caccgtcgcg cgcatcaagg
     4501 ccgacgccga ggccaaccgc ggcccgtgga cgctcaccgc gaccgcgccg aaggaaccgc
     4561 tgatcatcga cacggagtcc acctggacgc tgtcgctgat caaggccaac gagaagggcg
     4621 tgacgaacgc cccgatcgcg ttcaccctga ccgacgccaa gctggccgac ggcaagacga
     4681 gcggcacggc caccacgggc gccgacggcc agcccgccgc cgtgaaggtc atcccgaccg
     4741 ggccgaagcc gtcgatcgcg gccgtcgcgg actcccccgc cgaccggccg gtcgtgcact
     4801 tcccgatcca gacggacaac atgcagcgca tggtcacgac cggcggcgag aagaagctga
     4861 acgccgccgc gaacggccag gccaagaccg cgcccggcgc cgtgaagatc acgaagatcg
     4921 actcggagac caagaaggcc atcgcgggcg tcgcgctgcg cgtcacggcc aaggaccaga
     4981 ccacggccgc gaagaagcag gacgacacgg acctcgtcgg cacggacggc aagccgctgg
     5041 tgctgcagac cggccccgac ggcacggtcg aggtgccgga cctgcgcacc ccgcaggaga
     5101 tctgtctcgt cgaagtggcc gcccccaagg gttatgagga gttcttcgac ccgaaggcgc
     5161 cgccggcctc gtgcggcacg gtcgcggcgg gtcagacgct cgcgctcgaa ctggtgaaca
     5221 agccgaacaa gccggtcgtg cccagcacga ttcccgccgg tgcggacggt cagacgccgg
     5281 tcgcgaccgc gtcgttcgac actcagctga gtccgggcct gatgctgacg gcgggtggcc
     5341 tggtgctgct cggcgcggcg ctggcaggct tcctggtgtg gcgcaggcag tgagtcccaa
     5401 ggcttttctg accggcacgc tggtggcggg catcgccgct gccagcgtgc tggtcaccac
     5461 gtccgagacc gaggtcctca aaggacacgc ggtcgcggac gagatcccgg tggtcgggcc
     5521 ggggccggtg gcggacagcc tgagcaccgg ccgcggcccc gacctcaccg ggctgctcgg
     5581 cggggcgaac acggccaacg ccaggcccgc cgaccccacc ccgcagcagc aacagcccgc
     5641 accgcccaag gccggtccgg gttcggtgcg gctgccctcg ggcggttcgg ccacgctggt
     5701 gcgcaaagag gtcaaggacg gcgtgctgcc ggtgcccgac ggcatcggcg aggcgacctg
     5761 gtggggcacc gagctcgcgg gtgccgaggg ggcgacggtg ctggcggggc acgtcgactg
     5821 gaagggcgcg aagggcccgt tcgcggagct gtggcaggcg cagaacggcc gtgaggtcgt
     5881 gatcgccgac agcgcgggca aggagttcaa gttccgcatc aggcagatcg agaccgtccg
     5941 caaggaggag ctcccggcgc gtgccgtcga gttcttcggg ccgcgtgggc cgcaccggtt
     6001 ggtgctggtc acctgcggcg gcacgtgggt cggcggtcag caggggtacg aggcgaaccg
     6061 agtggtcatc gccgaacccg ttcagtagcc aattgcctcc accgcgcaac ccgttcgggt
     6121 gaccagtcgt ctcctaaggt gtgaagcggt ggggatggtt gaccacgggc gtggcgctgg
     6181 ggctggttct ggcgatcgtg atgaccctgg ggtcgcacaa ggagcagaca agtcaggcgg
     6241 actccggccc gttgccgatg gcccccagac tgcccgctcc caaggacgcg ggaccgacgc
     6301 cgaccgtgcc cgcgcccagt gccgaacagc tgcagaagca gccgtggatg cacaagctcg
     6361 caccgggcga gaagcccccg cagttcgtgc tcttctcctt cgacggcgcg gtgtccaagc
     6421 agcactggga caaggtcctg ccgatcgcga agtccaagaa cgcgcacgtg acgggcctgc
     6481 tgtccggcgt ctacatgctg gcggacccgg acaagaacca gtaccagcca ccggcgggac
     6541 tcaagcgcgg cctgtccgac atcgacttcg gcggcacccg gcaggacgtc aactcccgaa
     6601 tcgcctacct gaaccaggtg atcgccgacg gccacgagat cggcacgcac tacaacgggc
     6661 acttctgctc gaacggcacg cagccgtcgg tcgacaagtg ggacactgcg gcctggaacg
     6721 cggagctcgc ccagttcaaa cagatcgtcg acaggtcccg tgccgcgggg ctgaacctgc
     6781 ccgccgacgc cgtccggggt ggacggacgc cgtgcctgga aggcaactgg gaccaggctt
     6841 tccccgcgat ggccgcgaac ggcctcgtct acgacaccag caaggtcgcg ctcggcgtgc
     6901 agtggccgac cgtccaaaac ggactgtacg agttcccgat gcccgaggtg aaggttcccg
     6961 ggctgggcaa gcaggtcgtc atgatggact tcaacctctg gtactcgctc aaccaggcga
     7021 aggacgaacc ctcgcgggcg gccgacttct cccagatcgt cctcgacacc tacaagtcgg
     7081 tgcaccaggc cgcgctgaac ggcaaccgcg cgccgatagt cgtcggcaac cacttcaacg
     7141 agtggaacgg caacgcgttc tcgaccgcga tggaacagtt catggagtac gtgtgcgaca
     7201 agccggacac ggtgtgcgcc acctacaccg aggtgatcca gtggatgcag ctgcaggatc
     7261 cggcggtgct cgaccagctc cgccggatgc ccgctgctcg caactggtga ctagccgtcg
     7321 gtggagatga tccggtcgtc gttcgcgccc ggtgagccgt tcgcgtcccg gttggacgtt
     7381 ccgatccaca acgtgccgtc cggcgccgtg gtcaccgcac gcacccggcc gtagccggtg
     7441 aacaccgcct gcggggtgcc gagcgtggtg ccgttcaccg ggatcttcca cacgcgcttg
     7501 ccggtgaccg cgccgacgta cagggcgttc ttgtagaagg cgatgccggt cggaccggcc
     7561 tggctggtgg accacgtctt gaccgggttg gtcatgcccg cggtgttgca gttgccctca
     7621 caggtgggcc agccgtagtt cttgccggcc tcgatccggt tgatctcgtc ggtcgtgttg
     7681 ttgccgaact ccgtggcgta cgcggtgctg ccgatccagg tgatgccctg gacgttgcgg
     7741 tggccgatcg agtagacgac gctgccggcg cgagggttgc cggcagcggg cttgcccgtc
     7801 gcgtcgaagc ggagaacctt gccgcccaac gagttccagt tctgcgcgtt ggcggtgttc
     7861 tggccgtcgc ccgtggtggc ccacaggaag ccgtccggac cccattcgag gccgccgccg
     7921 ttgtggtagc ggttcttggg gatcccggtc acgatcggct gcggcgtgcc gccgagctgg
     7981 agcttggcga cgcggttgtc gctcgccgtc gagtagtaga tgaagaccga gttgtcggtc
     8041 gcgaagctct tcgacacggc gaggccgagc aggccgccct caccgccggt cgtctgggcc
     8101 tgttccaccg tgtccaggtc ggtcacggtc gtgcccttga tcttcttgat cttcttggtg
     8161 tcccgctcgg tgaagatgcc gctgccgtcc ggcaggaact cgatgtccca cgggatgtgc
     8221 agcttcgtgg cgagggtccg ttccgccaga accgacgggc cgtcctgtgc cgaggcgggc
     8281 agtgcgcaga gggatgcggc cacggcggtg caggccgcca cggctgcgat acgacgagca
     8341 cgcatgtgct ctccttcggg tccgctcgta aattgtctgc ggcggcggtg ttgcagggcg
     8401 tatttacgca atcacacatc gcaggcaccc gcaatagtga tcggatgtcc cgggacgccc
     8461 ctcgcctccg agcgggtgaa gcgaggggcg ttctccgcta cctctggtag ccgagctgtg
     8521 tgggtcagtt gccgtcggcg aggtggattc cgccgggcgt gatcacccag agtgagccgt
     8581 cgggaccggc gacctcgtcc cgcgtgcgac cgaggttggt gtagatcttg ccgcccgctc
     8641 cgctggtgtt cagcttgaac gtgccgccct tgagcgaggc catgtacagc gagcccttgt
     8701 aggtggtgag accggacgga gtggcctgcg aggtcggcca ctgcttcacc gggttggtca
     8761 tgccggacgt gctgcaggaa ccctcacagg tcggccagcc gtagttcttg ccggcgtcga
     8821 tccggttgag ctcgtcgacc ttgctggcgc cgatgtcgga gacgtagagc tgcgtgccga
     8881 cccaggtcag gccctgcacg ttgcggtggc cgtaggagta gacgagcgag ccgaacgggt
     8941 tgcccggcgc ggccttgccg tccttggtca tgcggaggac cttgccgccc aaggagttct
     9001 tgttctgcgc gttgttcccg ttctggccgt caccggtacc ggcgtagagg aagccgtcgg
     9061 gaccgaactt gatgcggccg ccgtggtggt actgcgagcc gcgcggaatt ccggtgacga
     9121 tcggcttcgg ggcgccgccg ccgatctgcc aggtggcgat ccggttgtcg gatcccgttg
     9181 tgtagtagag gaagagcgtc ttgtccgccg cgtacgtcgg tgacacggcg atgcccagca
     9241 ggcccgcctc cttggtcacc gagacgccgg ggatgtcgcc gaccttggtg accttgccct
     9301 ccttggtgat ggtggagacg gtcttggcgt ccttctgcgt gaagacgccg gtgccgtccg
     9361 gcaggaagtc gatgctccag gcctggctga ggccgctcgc gatggtcttc acggccatcg
     9421 cgccgacgtc gtccggtgtt gccgcggacg ccagtggagc actggagagt cctacggcga
     9481 gcgcgaggac gccgatgtgc gcacttcgac gagcacccat tgtgctgacc cctcaacttt
     9541 cgcgtcgtgc ggcgacggcg agcccgaaat cggagttttc gggctggggg cctctcgata
     9601 caaccacggt gtgtagtcac gggcgcatcc gccaatcggg tcacccctcc gatgacttta
     9661 ggtaacttta tgtacggtct agaccgtgac ggcccgacca cataccgtgt ggtcagccgc
     9721 cgcgccccca acggaaagcg cttgcacgcc cgccacgggc tggcaggcag gacacccgag
     9781 gagttgcgcc atgaacgttg ccgtcaccac caccgagacc aagctccccg aggtcaggcg
     9841 cgagtgggtc aagcccgact tccgcgactt cgagaccccg atggaggtca ccgcctacgc
     9901 ggctcgcagc tgacgtcagg cttcgcgccg gggttcccga ctgatgccgg gaatcccggc
     9961 tcccgcgcgt cgttcgtggt agaccgagga gtttccgacc atgactgccg tctctcccgc
    10021 ggagttcgtc gccgagctgc gcgccctcgc accccggtac tgggacagcc acccgttcca
    10081 cctgcgcatg cacgcgggcc agctgagcaa gcacgagctt caggcgtggg ccgcgaaccg
    10141 ctggtactac cagcgctgca tcgcgcagaa ggacgccgcg atcctctcga actgcccgtc
    10201 gccggagatc cgccgccagt ggcgtgagcg gatcgtctgg cacgacggca cgcagccggg
    10261 cgagggcggc gcggagaact ggatccgcct cgcggaagcc gtggggctga cgcgggaaga
    10321 ggtgctcgac gaacgtcacg tgctgcccgg cacgcgcttc gccgtcgacg cctacgtgaa
    10381 cttcgcgcgc accaagccgt gggtcgaggc catcgcctcc ggcctcaccg agatgttctc
    10441 gggcgcgttg atgcgcaagc gcttggcggc gttgcgggag cagtacccgt ggatcgccga
    10501 ggagggcttc gcctacttca ccaaccgcat ccaggcggtc gccggcgagg gacaggccac
    10561 tgtggacatc gtggtcgctc actcgctgac ccgcgaacag cagctggccg ccgtcgacgc
    10621 gctgtcgttc aagtgcgacg tgctgcgggc cgtgctggac gccgtcgact actactcggg
    10681 caagggcagg ccgtgacgac cgcggtcgcg ctggacgccg tgccgcggat ccggcgcggc
    10741 gtgaagtgcg cctacgacca gatccgggag gcgcacgtcg tgctgttccc cgagggtgtg
    10801 ctggtgctga acgagaccgc ggcttccgtt gtagcgcttt gtgatggcgt ccggtcggtc
    10861 ggcgacatcg ctgtcgtgct ggcggacgag tacgacggtg tcgaacccga ggacgtggcc
    10921 gaactggtcg cgcgcatggt cgaacgaagg gtggtggacg tcgatggctg aggcgccttt
    10981 cggcctgctg gccgagctga cgcaccggtg cccgttgcag tgcggttact gctcgaaccc
    11041 gctggagctg gtgcggcgcg acgccgagct gtcgaccgag gactggcggc gggtgttcga
    11101 ccaggcccgg gcgctgggct gcctccagat acacctgtcc ggcggcgagc cgttgctgcg
    11161 gccggacctg cccgaactgg tggcgcacgc gaacagcctc ggctgctacg tcaacctggt
    11221 cacgtcggga gtcggtctct cccgcgaccg gttgcgggaa ctggcttccc tgggtgtcga
    11281 ccacgtgcag ctctccctgc aggacgcgac gaaggaaggc aacgaccgga tcgccggcat
    11341 caaggcgttc gaccgcaagg tggaggccgc ggcgcacgtt ctggacgagg gcctgccgct
    11401 gacggtcaac accgtgctgc accggcagaa cctcgacaac atcgccggca tcatcgcgat
    11461 ggcggaacag atgggcgccg agcgcctgga actcgccaac acccagtact acggctgggc
    11521 gctgcgcaac cgcgcggtgc tgctgcccac gcgcgcacag ctcgccatcg ctgacccgat
    11581 cgtggctgcg gcgcaggaac gtctgcgcgg acggatggag atcgtctacg tcatcgcgga
    11641 ctaccacgag gcccacccga aaccctgcat gtacgggtgg ggcgcgcggc agctgacggt
    11701 ggcaccgaat ggcgacgtac tcccctgtcc cgccgccacg gtgatctcgt cgctgacgat
    11761 cgagaacgtg cgcgactcct cgttgcacga gatctggcac gactcgccgt cgttcaacgc
    11821 cttccgcggc ttcgagtgga tgcaggaccc ctgccgctcg tgcccgcgca aggagatcga
    11881 cttcggcggg tgccgctgtc aggcgttcca gctgaccggg gacgccgccg cgaccgatcc
    11941 cgtctgttcc ctgtcacctg agcggtccac tgtggacctg atcctggaga ccgagatggc
    12001 accggccgag gttcccgcga tggcgatgag gaagatgcgg tgaaggcggt actgctcggc
    12061 acgacggcgg gtggcggttt cccgcagtgg aactgcgcgt gcgccctgtg cgtgcgcgct
    12121 cggtccggct cgttgccgtc gcggtcgcag gactgcctgg cgatcagcgg caacggcacc
    12181 gactggtggc tggtcaacgc ttccccggac atccggacgc agatcgcctc gtgttcgttc
    12241 ctgaaccccg gtcccggcgc gcgcgacacc ccgttgcgcg gcgccctgtt caccgacgcg
    12301 gagctcgacc acactctcgg gctgctgacg ctgcgcgggg gcgcgggtct gacggtgtgg
    12361 gcgccgggcc cggttctgca cgcgttgcag gaccagttcg acctgcgcac ggtgatcgac
    12421 ggctacgcgc cggtggcgtg gcgtcaggtc gaggccgacc agtcgttctc gatcagcggg
    12481 ctgcgcgtgt cggcgatccc gatcagcggc aagcggccga agtacgcccg ttcgtccact
    12541 gtggatggtc attgggtggt cgcgtaccgg ttcgaggatc ctgtttccgg cggtgtgctg
    12601 gtctacgcgc cctgtctggc gtcgtggccc tccggtttcg acgaggtggt ggccggggcc
    12661 gactgcgtgc tgctggacgg cacgttctac gcggcgtcgg agatgggttc ggcgaccggc
    12721 agttcgtccg gccaggccgc catgggccac ctgccgatct ccgcgagcct gcctgagctg
    12781 cggcgattcc cgtccgtccg ccggctctac acgcacctca acaacaccaa cccggtgctc
    12841 gacccgtcgt cgccggagtt ctcgaaggtc cgggaggccg gcgtcgaggt tccgttggac
    12901 ggcacggtga tcgagctgta gatcggccac aatcaccgga tgtcctacgt gatcggtggc
    12961 cggccgctgg cagatcgact cgtcgcggag atgccgtcgt tcgtgcggca ggtgatcgcg
    13021 tcgctggtgc agcgcgtgcc cgcgtacgcc cagctgcccg cggaggagct cgacggcgac
    13081 atcttccgcg tcaccgagca cgccctgcgc gggttcgcgg ccgtgctcgc caccggctcg
    13141 ttgccctcgg ccgacgaact gcggttcctg cgcgagtcgg cggcgcggcg ggccgaggag
    13201 ggcgtgccga tcgacgtggt gctcaccgcc taccacgtgg gcatccaggt cgtgtgggag
    13261 acgctggtgc ccgaggcgcg cccggaggag gtctcggacg tgctcgcgct caacgcgttg
    13321 gcactgcggt acttgcagct cgtgacgccc gtggtgagcg ccgggtacct cgacgagcgg
    13381 cagacgatgt tcgacgacga acgctcggcg cgtgccacgt tgctcaccgg tctgctctcc
    13441 ggaaccgttg aggcgtcagg accgtacgtg gtgctggcgc tgcacatacc gccgcatccg
    13501 gacgagctgc tggacggggt ggacgcggcg gtcgccgggc ggcggaagct gcgccgcctg
    13561 cggaccgagc tggagcggca cagccgggag ccggtgctgt cgtcgctcac gcccgagggc
    13621 ggcctcgcgt tgctgccggg tgaggacccg ccgctggaac ggatcgtcgc ggacgtgacc
    13681 cgttcggcgg ggacaccggt gacggtggcg gcggtcgcgg cctcaccctc cgaggtcgcg
    13741 gccgccgcgg tcctggcgcg cgaggtgctg gccgtcgcgg tgcggtcggg tcccggcctc
    13801 taccggctcg ccgacgtgtt gctggagtac cagctgtccc ggccgagcgc ggccctgcga
    13861 ccgttggcgt cgatcgtcga gccgctgacc gaggaactcg tgcagacgct ggaggtctac
    13921 ctgcgacgcg ggtcgcggcg gccggctgct tccgagctgc acgtgcatcc gaacaccgtg
    13981 gactacaggt tgcgtcgagt cgcggagttg accgggctgg acccgacgcg gatcgagcac
    14041 gtcacgctgc tcgcggcggc gctggcggcg cggagggcgc gctgacgcag gggtaccccc
    14101 tggctgggaa cccctgcgtc acaacttacg cagcgggtcc gacaagatca gtcgccttcg
    14161 ccaccgcggt gccgaaggcc ttcatgccgg ccgcgttcgg gtgcagcggc gccgcgatcg
    14221 tcgtcgggat caggccctcc aggtagcggt ccgccggcgc cgcgcagatg tcgtgcccga
    14281 ccgtcacggc cgcgaagtcc acgaacgtcg cgccgcgctt ggccgcctcg gccttcgcgg
    14341 tcgcgctgat cctgttcatc acgctctgca ggtagtcgcc gtcgcggccc cagaccggct
    14401 ggcgcgggta gcagccaccg ggcctgatgt aggtgccgta gccggtgacc agcagcctcg
    14461 cgttcggcga gcggcgcttg atctcgtcca gcgcggcacc gaactccggc gcccacgcgt
    14521 cgacggcctg ggcgagctgg tcggtgccgc cggcgttgta gcggtcgtga caggagacgc
    14581 ctaccggttc cggcaggagg ttgacgcagc tcagcgcggt ctggaacagg ccgatgtcgt
    14641 tggcgccgat cgtcagcgac acgaggtcgg tggtgggctt cagcgcgtcg tactgcggcg
    14701 cgacgaaccc gaactggcgg cccccgaagt cgtcggtctt cgcaccggag cacgtgacgt
    14761 cggtgagcct cgcgccgagg accttggcgg cgacctgcgg gtagttccgg tcactgcgca
    14821 ggcaccacag ggccgggtcc tggttcggga tcagcgggcc ggccgccgcc gagtcgccca
    14881 gggccacgta gtcgagggag tccgcctgtg cggtacttgt tccggcgacc aacatcgcca
    14941 cgacagccaa cccggccacg attcgcatcc cgatcctcca acgtcgttgt caggtctgct
    15001 catcgtggtg gctcaggtca cttgtgcggg tgggacgttg cccagagtca tccggtcgtg
    15061 tttgtgaccg atcacaatgg gcctcgtgac tcctggggaa ctcctcacgt tggccgcgca
    15121 gtcctgcgtg gacgccgcca aactgctgca cgacgtccgc gtcgacgtgt cgccgaaggg
    15181 cacgttcgac caggtcagca cggccgatct ggaggtggag gcgttcctgc gggcggccct
    15241 ggtctccggt gcccccggct cggccgtggt cggcgaggag ctgggcagct cgtccgcccc
    15301 gctcacctgg tacgtcgacc cgatcgacgg cacgcggaac ttcgtgcgcg gcatcccgtt
    15361 gtcgtgcatc tcggtcgcgg cggccgtcga gggcacgctg gtcgcgggct gcgtgctcga
    15421 cccgttccgc gacgagctgt tcacggcggc cgtcggcgtt ccgttccgcg tccgctccag
    15481 cggcctctcg atcccgcccg gcacgagccc gcggccgctc gtgctgaccg acatcccgtt
    15541 gcccggcagc ccgcaccagg gcgagatgga gctcctgaac gaccttctgg acgtcgctga
    15601 cgtgcgccgc gtctactcga cggccctgtc gctcgcgtgg gtcgcgacgg gcagggcgga
    15661 cgcggcggcg aacatcggca tccacccgtg ggacgtcgcg gcgggcgcgg tcctggtccg
    15721 cgaggcgggc ggggagttcc gcgagatcgg ttcgaacggg ttcgtcgccg gccggggtga
    15781 gatcgtcggc tggctggcgc aacgaatgga aggcatcgtc tcgtgatcga tctcagcggc
    15841 agggtcgtgc tcgtcaccgg caccgacggc cccatcggca acggcatcgc tctccggttc
    15901 gaggccgcag gcgcccaggt cgtccgtcac cggggcgtcg gggacggcga cctgcgcacg
    15961 tcggccaagc gcgtggtcga cgacgccttc gcccggcacg gcaggttgga cgcggtggtc
    16021 aacaacgccg gcgtccaacc cgtggaaccg ttgccggaca tgacatccgc gcagtggcag
    16081 ttcgtcgtgg acaccaacct gacggccccg ttcgccgtca cccaggccgc cgccgcgcac
    16141 ctcccggaag gcggctcggt cacgcacatc gcgtcgatcg agggcacgag tccggcaccc
    16201 ggccacgccc actacgcggc ctcgaaggcc ggcctgatca tgcacgcgcg agcggcggcg
    16261 ctggagtacg gatcgcgcgg catccgggtc aacacggtct cgccgggcct gatcacgcgc
    16321 cccggcatcg aggagcagtg gccggagggc gttgcccggt ggcgtgcggc ggcaccgctc
    16381 acccgcctcg gcactcccga ggacgtcggt gatgcgtgcg tgttcctggc cagcgacctg
    16441 gctcggtgga tcaccggcca cgacctcgtg gtcgatggag gagtgaccgc ccggccgacc
    16501 tggtgacccc ggtcaccaca acagcatgtc gacatgacac taagtaatca catgcgcgtt
    16561 ttacaccagt tcgtacagga ccgacagggc acaaagaccc caccggaagt gtccatctat
    16621 aggcgataaa aaacctggtc agacgcgata agtaactcag cgcgcacggt ccgtatccat
    16681 cggctatgaa atgtctcaac tcggtcacat gtcaaaattt gcctacccag agtgataaca
    16741 ggcacgtcct tctcgtcgaa acctcaacca gtcgcactgg accagagggg gacggacgac
    16801 atgacatctg ggaaccgagc agtttcccga cgcacgctcc tgaccgccgc actcggcggt
    16861 gccgccgtgg gcgtcgtcgg ccacagcctg ttcgccggag ccgccaacgc ggcgcccgcg
    16921 gccggccgca agaaactcct gatcggcagc gtggatccgc tcggcaacgg gatcgtccag
    16981 ctgaccgacc cgagcctgac cggcgagcag acgatcgtcg ccgtcaacgg ccagccgaac
    17041 gggatcgtgg gctcgcccga cggtctgcgc gcttacgtgg ggacggtctt cggaccggga
    17101 ctgagcgtcg tggacgtgga cggcggccgg gtgaccagcg aggtcgcggt cggcgggttc
    17161 gtcaacgaac tcgtcgtctc accggacggc aagaccgtct acgtcgcgac cgggtccagc
    17221 ggcgccgggg gctcccgcgg acacgtggcc gtggtcgaca cggcgaccgg caaggtgcgc
    17281 gcgctgatca acgcaggtct gctgccgcgc acgctggcgc tgacgccgga cggcacgcag
    17341 ctgttcgtcg gggacgagcg agccaagggc atcacgatca tcgacaccgc gaagaacgcc
    17401 gtgtcgggtt cgttcaagac cgagaagtcg ccgttgcagc tcgccatcga ccccaagggc
    17461 aagagcctgt acgtggcgtc gtcgcgtgag ctgatcacgt tcgacctgcg cggcgggaag
    17521 tccggttcga ccgagctcga aggcgtcccc tgcggtctgg cggtgcaccc gaacggaacg
    17581 ttcgcggtgg tgagcctcta cacgggccgc gccaccgact cccagctggt gacggtgaac
    17641 atcaactcca acaaggtcag gacgaaggag ggcaacggca aggcgaacgg tcctctggcg
    17701 atgagcaagg acggtgcgcg cgcgttcgtg ctggacaaga agaaccgcaa ggtcatctca
    17761 gcggacacgg actccggcaa gccggacagc tctctgtcga cccccaactc gaacacgccg
    17821 acctccgtcg cgttcgtcga aaccgcctga gcgccggagg gaatccacga tgcccatctc
    17881 catgtccgtg aagaccctgg actacacccc ggcctacccg ccctacccga gcctctggat
    17941 ggccggctac ggcggcgcgc cgcgcggcaa ccagggcctg gtcgaccgca ggctgcgcgc
    18001 ccagtgcatc gtcatcgacg acggcgccgg gcccaaggtc atgctccgcg tcgacgtcgt
    18061 cagcatcccg cgatacgtcc atcaggcgat caggtccggc gtgacaccga tggtggacga
    18121 ccacgacggc aacttcctga ttatctgcag ccacacccac tccggcccgt tcatcggcac
    18181 cacacggccg aatccctacg tgatgatgag cctcacgccc gcggacgtca gcgcgatcga
    18241 ggacacgacc aacgtcttca tcgcgcagat gatcgagctc gtggagcaga ccctcgcgat
    18301 ggcccgcacg caggtcacgt tgtggtacaa ggaaggcaac gcgtcgatcg gctacaaccg
    18361 cgccggggag cccaacgacc tctccacggt caacgcgctg atcgcccgcc gcacgagcga
    18421 caacggcctg cacaccgtcc tcttcggata cgcctgccac gccgtggcac ggggcaacga
    18481 caggtacttc tgcagcgact tccccggtgc cgccaccgac gtgatcagca acgcgctcgg
    18541 cgtgcaggca ctgttcttcc agggcgccgc cggtgaccag gaacccaacg acccgcatgg
    18601 ccccggccag gtcacgaacc tcggcacgat cctcggcaac gaggtcgtgg cgatggtgaa
    18661 ctcgggcggc tggaccgccg tcaccggccc gatcagcacg tactacgagg agctcagcct
    18721 cccgctcacc gtggacctcg gcgacccggc cgcggtgatc cgcgctcgca acagctacag
    18781 cgaccggctc gacaacctcc ccccgagcga cttcgcctac cgccacgccg aggtcatgct
    18841 cgaggagatc gcgggcgtgg gccttccccg tgtgttcccg atgcccatcc agcgctggaa
    18901 gatgggtggc ctcaacatct tcgcgatgtc gcacgaggtt ctctcggaat acgcggtgaa
    18961 gttgcggaac cagaccccgg gcaagctgtg ggtgatggcc tacgccaacg agaccgaggg
    19021 ctacgtggcg gccaacggca tcctgcagga cggcggcgcg gtgcgctggg gttacgaagc
    19081 cggctgggtc gacaaccccg atatctccgg cgaggccacg tggacgacct tctacccctg
    19141 gcccgcacca ctgaagttca gcccgagcgg ccccgccgca ccagggacga ccgagcgcgt
    19201 cgtcctcgac gccagcacag ccatgctgaa tctctgaggg gtggatcgaa gacatgccag
    19261 gacccagcac cacactgtcg gcccgctacg gcctgactcc ggtctacccg tgcggcacga
    19321 ccggcgacct cttcctgttc gagcacatga caccgaccac cggcaccttc gcctggggcc
    19381 agagctacca ggtcggcgcc ggctggcagg gccgggtgct cgcaggcccg agcggctgga
    19441 tgttcagcat caccaccacc ggtgagctga gactgttgca ctacaacgga accaactggg
    19501 acgacctcga cggcagccag taccgcgtcc tcggccaggg ctggtcgtac accgcggcga
    19561 acacccgcaa ccgcatctcg gtcgacgagg acggcgtcct ctacaccctc gacgcggccg
    19621 gcaacctcaa ggcgcactac ttcaacttca ccacccagca gtgggcggtg cagggcgcac
    19681 tgctggccac gggcctgacc cagtacaacg cgatcgtcgc aacgagccgt ggcgtggtct
    19741 acgcgcgcaa cgcggccggc gcgatgtacc gctactacat caacttctgg tcgggcgcga
    19801 ccgcgacgtg gttcacgccg gcctcccccg tcacgacggg gtggcagaac ctgaagaacc
    19861 tcagctcggc cggcggcgag gcgttctacg ccgtgaacca gaacaacgga aacctgctct
    19921 ggtacagcta caacccggtg accaacgcgt ggaagaacgc gaagatcatc ggcagcgggt
    19981 ggagcaacga gcaggacgtc gtcgtgcagt ccaacgcgtg cagccggttc ccctgggaca
    20041 cggcgtgcaa ctcgttcggg atgcaggacg gcggggccgt gatcacgcgg ctcaaccagg
    20101 tgaagaagaa ctgacctgac gccgatggcg tcgtgaccaa gaccacaccg ttgacgcgcc
    20161 gctcactcgg ctcggcgtcc acctgaacgc tgaccaagat caacttacga ttactctccg
    20221 ctcccctccg gacaccgttc ggaggggagc ggagctcgtt cagacgaccg cgagaccacc
    20281 gccgagaacg gctgaaatgc ctgatcaggc accagatcct ggggtggatt cagatggtgc
    20341 ccccgacggg attcgaaccc gtactgtgat ccttttaagg gacctgcctc taccgattgg
    20401 gctacggggg cgcggtgagc ctaggccttg atcgtcggct tgtgtgagcg gatggtcttt
    20461 tctcgcccga gcggcccagc gaattggact agagcgagca tccggctaag cgtcgaacgg
    20521 acccgaacat cagcgtgccc tccccgctcc gagcagctcc ttgaagcgca gcgccaccca
    20581 gtcgtgcacg gccgcggaga cgctgttgtc gcccgccctg tgttcgaacc agcgccagtc
    20641 gcagttgacg ttgatctcca ggaacacgtg gtcaccactg ccggtcacca gcaggtcgaa
    20701 cgccgccacc tggacgcgcc agtggcgggc cagggcgaag agcctgtccg agagggacgc
    20761 gggcaccgag gtcggcgtga cgcggaccgc gtcgggatcc acccagagct gggccgggtc
    20821 gagtttgtcg acctggtagg cgatgcagcg ctcgcccacg acgaacacgc gcagttcggt
    20881 gtccgagggg acgtactcct ggacgatcac cggtgcgggt tcgggggcgt ccgaggccct
    20941 ggaggtttcc agggggcgcg ggaacaggcc gtgttgtacg cctgggcgtg gttccaggag
    21001 gtgcctgccg gccgttttga cgatgcaggc gccgccgcct ggacgcgtgc ggcctggacg
    21061 cgtcgtcacg gccgtgcgcg gtacacgcaa gccgaacgcg ctggcgtcgg aaagctgcgt
    21121 gagacggtcc aggtgcgtcg agaagcgtga tgggttcacg tgagcccagt cggagcgtga
    21181 ggacagccag ttggccactg aggcccattg gtcgacggcg taggcgccgg ccagggttcc
    21241 cggctccacc gggactgcgg agagctcgaa gtggcggcgc cagaccagca gggggcgcag
    21301 gagccagcgg tcgagttcga tcagcggctg gtcggtgtag accgacaagg ggaggtcgac
    21361 gcagcggtcg gcgtcgatgc gggccatccg gatgccgcgc tcggccagtg cgatggagag
    21421 ttcgttcatc tccatgtcgg cggcgcgggc caggacgagc acgcagggtt gcgggttgcc
    21481 gtcgccctcg tcgaccatgc cgaggcggtg gacctgttcc tggaagtcca gacacttggg
    21541 cggggagcgg aagagatatt cctgaccctg gagcagaagt ggtctggcag cctcggacgg
    21601 ggcacctggc acccgtccgt cagccgacct gctcaatcgt ccttcttgct gcggaaaacc
    21661 tgccccgcct gcgcgtactc tgcggcgtac tgcgccagcg cggggtcctc gatctcgcca
    21721 cgacgaagct gtgcggccag ctcctcgaga gacatcggga tcacctctct ccccacatgg
    21781 cgaatcacgc attcaggtga tgcaccagcc gtagtctccg aaacacgtaa cgcaatgtca
    21841 aggcgaccct tggagcttta ctccgattgg gcgcttaagt tccgcctgcg gtccagcgaa
    21901 gtgccccgaa cgaggagatc gtccggggca cacgtcactc acagagagtg aacgtcagtg
    21961 tcactcccag aagcagtctc ctgaggttgt cgacacgaga agagcgctcg tgtcgacaac
    22021 ctcaggactg cactgcgcga tcg
//
