LOCUS       NZ_FOYL01000007        22562 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea waywayandensis strain DSM 44232, whole genome shotgun
            sequence.
ACCESSION   NZ_FOYL01000007
VERSION     NZ_FOYL01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea waywayandensis
  ORGANISM  Lentzea waywayandensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900115955.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:54:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,449
            CDSs (total)                      :: 9,363
            Genes (coding)                    :: 9,244
            CDSs (with protein)               :: 9,244
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 26 of 119
            Pseudo Genes (incomplete)         :: 101 of 119
            Pseudo Genes (internal stop)      :: 5 of 119
            Pseudo Genes (multiple problems)  :: 12 of 119
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:39:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 326427
            Orig. end                         :: 348989
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOYL01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22562
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22562
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22562
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12562](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12562
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(173..187)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(648..1418)
                     /locus_tag="BM417_RS27095"
                     /old_locus_tag="SAMN04488564_107320"
     CDS             complement(648..1418)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223993.1"
                     /locus_tag="BM417_RS27095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107320"
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_093600219.1"
                     /transl_table=11
                     /translation="MGSQITEGLGQAWAMIATFVPKLLGFLLVLVIGWFIAKALAKGVQ
                     FLLKRVGFEKLVEKSGLTGAMRQSSMDASGLIAKIVYYFVLLIALQLAFGVFGASNPVS
                     TLLNEVIAYLPRIVVALVLVIVASAIGTALKGLVSGALGQRTYTKLMGNITYGFVMALG
                     IIAALNQLGIAISVTMPVLIAVLATVAGVIVIGVGGGLVRPMQQRWEGWLTRVQDEAQA
                     QSPMPRASQEMPANVGGRMGDMQTPPSGTPMSER"
     misc_feature    1594..1607
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            complement(1625..3181)
                     /locus_tag="BM417_RS27100"
                     /old_locus_tag="SAMN04488564_107321"
     CDS             complement(1625..3181)
                     /NRPS_PKS="Domain: Abhydrolase_1 (88-275). E-value:
                     2.9e-19. Score: 61.6. Matches aSDomain:
                     nrpspksdomains_BM417_RS27100_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099013.1"
                     /locus_tag="BM417_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107321"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_245822189.1"
                     /sec_met_domain="PF00561 (E-value: 4.7e-24, bitscore: 80.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRFPALALSVVALLTTGVTAAADPPDPLAEFHAQPVKWAPCSGK
                     LAELECATLVAPLDYAKPGGDRINLTISRKKAVAADRRRGVLFTNPGGPGGSGLGLPLF
                     LAKSELSQVYDVIGIDPRGVGGSTALNCRTAPAIAEPESRPADGEFGKWAAEAREAEEA
                     CQKSGGGIRQFISTANTARDMDVVRAVLGEQKINYLGYSYGTYLGAVYGTLFPNRLDRS
                     VLDSAVHPEWIWHEQFRQQAVAYRMDVEAWAAWVGERNEKFGLGKSRDEVLAEVEKVAA
                     KLHATPIGEHNRSSFDGATGVGARYRPLWSDLAAIVTKLRSGEKPDNAEGAKAGQVLAK
                     TGLEELRSGVFDTVTCESDWPTDLHVYYEDMRMFRERYPYGFGIVRAAPMTCTFRSFTP
                     PEPAVRIGRNGYPIGVVVQSEGDTQTQYASGPAMAQRLGHNLITVTDEGKHGLYNGGNK
                     CVDDKVNRYLIDGALPGSSSECTGDPRPDVPKDGQGGAAPALSPEGIQAYLDGRGLSAR
                     P"
     aSDomain        complement(2357..2917)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS27100_Abhydrolase_1.1"
                     /evalue="2.90E-19"
                     /label="BM417_RS27100_Abhydrolase_1.1"
                     /locus_tag="BM417_RS27100"
                     /protein_end="275"
                     /protein_start="88"
                     /score="61.6"
                     /tool="antismash"
                     /translation="TNPGGPGGSGLGLPLFLAKSELSQVYDVIGIDPRGVGGSTALNCR
                     TAPAIAEPESRPADGEFGKWAAEAREAEEACQKSGGGIRQFISTANTARDMDVVRAVLG
                     EQKINYLGYSYGTYLGAVYGTLFPNRLDRSVLDSAVHPEWIWHEQFRQQAVAYRMDVEA
                     WAAWVGERNEKFGLGKSRDEVLAE"
     gene            3686..>4453
                     /locus_tag="BM417_RS50325"
                     /pseudo=""
     CDS             3686..>4453
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037653.5"
                     /locus_tag="BM417_RS50325"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="PucR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEGVLRYGREIAFSAATSYATAAEARGAWDARLEALVVDGIVRGD
                     PEESLLSRAAALGWDPAIEATVLVGNPGGEDPPTIIYSVRSKAARAGRPVLLSVQGSRL
                     VVVLGGPTETGDDVLGRISEGFGEGPVVAGPTVTNLSEAHRSASDALSGLRAVVGWPAA
                     PRPVRSLDLLPERALAGDPEAEWQLVDRVARPLEDAGGALLETVDAFLEVGGVLETCAK
                     RLFVHPNTVRYRLRRVQEMTGRNAHDARDALVLR"
     gene            complement(<4428..4532)
                     /locus_tag="BM417_RS50330"
                     /pseudo=""
     CDS             complement(<4428..4532)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017333.5"
                     /locus_tag="BM417_RS50330"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCAKSVTARSATTGPGREQGVLQTKRREAQARLER"
     misc_feature    complement(4512..4527)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     misc_feature    4612..4628
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.9"
                     /tool="antismash"
     gene            4697..5626
                     /locus_tag="BM417_RS27110"
                     /old_locus_tag="SAMN04488564_107323"
     CDS             4697..5626
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (6-285). E-value: 1e-44. Score:
                     145.1. Matches aSDomain:
                     nrpspksdomains_BM417_RS27110_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099011.1"
                     /locus_tag="BM417_RS27110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107323"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_093600228.1"
                     /sec_met_domain="PKS_AT (E-value: 8.1e-44, bitscore: 145.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIALLAPGQGSQTPGMLTPWLELEGAEKQVRAWSEITGLDLVRLG
                     TTAEADEIVDTAITQPLVVALALLAFGELRRRVELPSAVIVGGHSVGELAAASVAGVIS
                     ADDAVALAAVRGAAMAEACAQEPTGMAAVLGGDEPEVLARLEELGLVPANRNGAGQIVA
                     AGPRAALDELAENPPGTAKVRKLAVAGAFHTKYMAPAEDAVRARAAEVTTHDPLLPLLS
                     NKDGQVVTEGTEVLRRLVSQVTSPVRWDVCQATLVEKGIAGSIELPPAGALTGLAKRAM
                     KGTATLALKTPDQFEKVAELFDTVGADK"
     CDS_motif       4715..4747
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM417_RS27110_0001"
                     /evalue="3.70E-03"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="BM417_RS27110"
                     /protein_end="17"
                     /protein_start="6"
                     /score="10.4"
                     /tool="antismash"
                     /translation="PGQGSQTPGML"
     aSDomain        4715..5551
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS27110_PKS_AT.1"
                     /evalue="1.00E-44"
                     /label="BM417_RS27110_PKS_AT.1"
                     /locus_tag="BM417_RS27110"
                     /protein_end="285"
                     /protein_start="6"
                     /score="145.1"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PGQGSQTPGMLTPWLELEGAEKQVRAWSEITGLDLVRLGTTAEAD
                     EIVDTAITQPLVVALALLAFGELRRRVELPSAVIVGGHSVGELAAASVAGVISADDAVA
                     LAAVRGAAMAEACAQEPTGMAAVLGGDEPEVLARLEELGLVPANRNGAGQIVAAGPRAA
                     LDELAENPPGTAKVRKLAVAGAFHTKYMAPAEDAVRARAAEVTTHDPLLPLLSNKDGQV
                     VTEGTEVLRRLVSQVTSPVRWDVCQATLVEKGIAGSIELPPAGALTGLAKRAMKGTA"
     CDS_motif       4955..5056
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM417_RS27110_0002"
                     /evalue="1.20E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="BM417_RS27110"
                     /protein_end="120"
                     /protein_start="86"
                     /score="43.0"
                     /tool="antismash"
                     /translation="GGHSVGELAAASVAGVISADDAVALAAVRGAAMA"
     gene            5623..6600
                     /locus_tag="BM417_RS27115"
                     /old_locus_tag="SAMN04488564_107324"
     CDS             5623..6600
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683046.1"
                     /locus_tag="BM417_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107324"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_093600231.1"
                     /sec_met_domain="fabH (E-value: 1e-103, bitscore: 341.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTFQAPHAAAGSRIIGLGSYQPETVVSNHDLAQRMDTSDEWVRE
                     RVGIVNRHVAAKDEGVVDMSVAAGTKAIADAGLTAADIGGVIVATCTMPSTIPNAAAQV
                     ATRLGIKAAAAFDLNAACAGFCYAVATAADIVRGGAVKNFLVIGAEKLTDWTHPDDRST
                     AIIFADGAGAVVVGASDENHIGPVAWGSDGSMSEVIRIDDRDSFIHQEGQTVFRWATTQ
                     IAPVALRAAELAGVELSEVDVFAPHQANLRIIEAIAKRLRNNGAREDLKVARDIVESGN
                     TSSASIPMALDHMRSAGEISSGDVVLMVGFGAGLSYAGQVIRCP"
     gene            6647..6883
                     /locus_tag="BM417_RS27120"
                     /old_locus_tag="SAMN04488564_107325"
     CDS             6647..6883
                     /NRPS_PKS="Domain: PP-binding (8-74). E-value: 4.7e-19.
                     Score: 60.5. Matches aSDomain:
                     nrpspksdomains_BM417_RS27120_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657583.1"
                     /locus_tag="BM417_RS27120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107325"
                     /product="acyl carrier protein"
                     /protein_id="WP_030465146.1"
                     /sec_met_domain="PP-binding (E-value: 1.9e-18, bitscore:
                     61.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 0.00067, bitscore:
                     14.8, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNVLSGLAEIVEEVAGVAADDVTAEKSFVDDLDIDSLSMVEIA
                     VQAEDKFGVKIPDDELANLKTVGDAVNYITSNK"
     aSDomain        6671..6868
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS27120_PP-binding.1"
                     /evalue="4.70E-19"
                     /label="BM417_RS27120_PP-binding.1"
                     /locus_tag="BM417_RS27120"
                     /protein_end="74"
                     /protein_start="8"
                     /score="60.5"
                     /tool="antismash"
                     /translation="LAEIVEEVAGVAADDVTAEKSFVDDLDIDSLSMVEIAVQAEDKFG
                     VKIPDDELANLKTVGDAVNYI"
     gene            6880..8115
                     /gene="fabF"
                     /locus_tag="BM417_RS27125"
                     /old_locus_tag="SAMN04488564_107326"
     CDS             6880..8115
                     /EC_number="2.3.1.179"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (65-406). E-value:
                     3.2e-48. Score: 156.6. Matches aSDomain:
                     nrpspksdomains_BM417_RS27125_PKS_KS.1"
                     /codon_start=1
                     /gene="fabF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FabF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017984122.1"
                     /locus_tag="BM417_RS27125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107326"
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="WP_093600234.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.9e-60, bitscore:
                     198.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="FabF (E-value: 4.4e-172, bitscore: 567.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSGIEVVITGLGATTPLGGDVTSTWDALLAGKSGVGPMTHEWVA
                     KYDLPVKIASELVVDPTEVLPRVEARRLDRSEQVAIVASRQAWSDAGHNDDTVDKQRLA
                     VIIGTGIGGAITLLTQDDLLEQHGLRKVSPLTVPMLMPNGPAAHVGLELKAQAGVHAPV
                     SACASGAEAIAWAYRMIMSGEADVVVAGGAEACITAIPVAGFSQARTMSTRNDEPEKAS
                     RPFDTARDGFVLGEGAGVMVLERREFAEARGAKIYGRLAGIGTSADGYHITAPDPEGVG
                     QSRAIAAALRSGGIDPSDVGHVNCHATSTPVGDVAETVAIRKAIGDHPVLTAPKGSLGH
                     LLGAAGAVEAIITVLSIRDGIVPQTLNLENLDPAVTLDVVAGEPRKIKLDAAVNDSFGF
                     GGHNVALAFTPA"
     aSDomain        7075..8097
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS27125_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.20E-48"
                     /label="BM417_RS27125_PKS_KS.1"
                     /locus_tag="BM417_RS27125"
                     /protein_end="406"
                     /protein_start="65"
                     /score="156.6"
                     /tool="antismash"
                     /translation="PRVEARRLDRSEQVAIVASRQAWSDAGHNDDTVDKQRLAVIIGTG
                     IGGAITLLTQDDLLEQHGLRKVSPLTVPMLMPNGPAAHVGLELKAQAGVHAPVSACASG
                     AEAIAWAYRMIMSGEADVVVAGGAEACITAIPVAGFSQARTMSTRNDEPEKASRPFDTA
                     RDGFVLGEGAGVMVLERREFAEARGAKIYGRLAGIGTSADGYHITAPDPEGVGQSRAIA
                     AALRSGGIDPSDVGHVNCHATSTPVGDVAETVAIRKAIGDHPVLTAPKGSLGHLLGAAG
                     AVEAIITVLSIRDGIVPQTLNLENLDPAVTLDVVAGEPRKIKLDAAVNDSFGFGGHNVA
                     L"
     gene            complement(8825..9397)
                     /locus_tag="BM417_RS27130"
                     /old_locus_tag="SAMN04488564_107327"
     CDS             complement(8825..9397)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS27130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_107327"
                     /product="hypothetical protein"
                     /protein_id="WP_143138814.1"
                     /transl_table=11
                     /translation="MGSVASRWLVPAVVVITGAAVAAGMVGRTVYSRPAEAKGAPVVAS
                     SSVAGPVPGSAEVRLSPDSFTHPDRTAVQRVLQAYFDAINSRDFDAWRGVVSARRVSST
                     PEASWVAAYETTEDGGMVVQRIESDVVARRLRALISFVSTQDVAKAPPALPEGCIRWRV
                     VYVLVWEGGVLKVDEAAENRNPQMEKC"
     misc_feature    complement(9442..9451)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     misc_feature    9456..9469
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.6"
                     /tool="antismash"
     misc_feature    9456..9472
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 21.88"
                     /tool="antismash"
     misc_feature    complement(9466..9480)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.26"
                     /tool="antismash"
     misc_feature    9515..9527
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     misc_feature    9534..9547
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.1"
                     /tool="antismash"
     misc_feature    9535..9548
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.58"
                     /tool="antismash"
     misc_feature    complement(9536..9549)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.59"
                     /tool="antismash"
     misc_feature    9948..9964
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            10001..12562
                     /gene="lanKC"
                     /locus_tag="BM417_RS27135"
                     /old_locus_tag="SAMN04488564_107328"
     CDS             10001..12562
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099006.1"
                     /locus_tag="BM417_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107328"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_093600240.1"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1065.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.9e-15, bitscore: 51.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.1e-15, bitscore:
                     50.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYEAYCFADRQFYDLQSSTESTPKDDFSTELPALPPDWATVE
                     RNVWRHHHPMGVQLPNQGWKIHVSAGLDNAGRVLKATYDYCVERRISFKYLQTMSIVLA
                     RNSKYAPREGSGKLVTIYPLDSAHLEAILTGLAHVLEGEHGAYILSDLRFGKGPLYVRY
                     GGFAEQWLEVDGQQVLAIEGADGTLIPDRRKPVFSLPEWIELPAFLKPHLAERNAGDPA
                     RFQYQIKSSLHFSNGGGVYLATRKSDGKEVVLKEARPHAGLDREGEDAVARLDREYEIL
                     TKLQGIKGVPEVYDRFTEWEHLFVAMEFMPGRSLGQWLGRHYPLTHKDVSDETITEYKA
                     RALAMVDRVESLMAEVHERGVVFGDLHTLNILVDDEDEISLIDFELSSTIDAVRKPTLG
                     APGFQAPRDRDGFDIDAHPLAALRLWIFLPLNTVLELAPAKIRQHVRVIQQRFGLTDEY
                     CAPIVDVLTPRVDPPTDPAFTEFDEETPDWALVRKEIATAILHSATPHRQDRLFPGDIE
                     QFETGGAGFGYGAAGVLHALAESGEGRFPEHEEWLLDALRKDPPKQPGFYVGAHGIAHV
                     LENFGHHDAATEIVESYAELVPSTQDHGLSAGLSGIGLNLLHFANSREDDSFAAQAEHL
                     AQRLAKQLADAPGPADKAKAGLLHGWSGPALFFLRMFEHTGERRWLKLSEQALERDLAE
                     TMIALDGSLQVRDGTLRSLPYVGIGGAGIALVLTEFAQQAPERPCVEKLPELLTGCTGE
                     FVIQPAFTLGRAGLLATLAHATRHRPNERFERAIGQHLKALGWHATRYGGGLAFPGVQL
                     RRLSMDLNTGGAGVLLALASTVDGRAPLPFLGSRTPVLADR"
     gene            12603..12764
                     /locus_tag="BM417_RS27140"
                     /old_locus_tag="SAMN04488564_107329"
     CDS             12603..12764
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800163.1"
                     /locus_tag="BM417_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107329"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_093600243.1"
                     /transl_table=11
                     /translation="MGFILDMQDLETPEAPANMMAGGSGGGGGGSTTASSASLLLPCSH
                     SSASLLLC"
     CDS_motif       12603..12668
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGFILDMQDLETPEAPANMMAG"
                     /locus_tag="BM417_RS27140_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12669..12764
                     /prepeptide="core"
                     /locus_tag="BM417_RS27140_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="4.80"
                     /molecular_weight="2537.8"
                     /monoisotopic_mass="2536.3"
                     /core_sequence="GSGGGGGGSTTASSASLLLPCSHSSASLLLC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGFILDMQDLETPEAPANMMAG"
                     /leader_location="[12602:12668](+)"
                     /alternative_weights="2555.8"
                     /alternative_weights="2573.8"
                     /alternative_weights="2591.8"
                     /alternative_weights="2609.9"
                     /alternative_weights="2627.9"
                     /alternative_weights="2645.9"
                     /alternative_weights="2663.9"
                     /alternative_weights="2681.9"
                     /alternative_weights="2700.0"
     gene            12909..14525
                     /locus_tag="BM417_RS27145"
                     /old_locus_tag="SAMN04488564_107330"
     CDS             12909..14525
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669539.1"
                     /locus_tag="BM417_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107330"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_093600246.1"
                     /transl_table=11
                     /translation="MTKPGDQLLFSTVKRDYRPWLLLLNAAVATTGGLLLPAALAGAVD
                     MALSGTFVLATIVFLLVLAGVEILGDAIGIILAASITARATAWLRRRLTRRLLTLGHPS
                     PFAAGDAVSRVTGDCGNAGSVAVTVISLAVTAVSSVGSVIALALLDWRLAAVFLVSAPL
                     AGYLVRTHMRLTADDVLAYQEVSGEVSARLLDSVSGLRTIAAAGIADRETNRVLEPLPR
                     LAAAGAGMWRTQAKMMWRAGLLLPAVEVAVLTAAGFGVMEGRLSTGDVLAALGYAALGM
                     GIVGQMTQLTVLERTRASAGRIAEVLDTPAPKRPAPKPSNGVIELRHVSVGDALHDVNL
                     MIPAGTFAAIVGSSGAGKSTLAAVLGGLSAVDAGEVVGDDAVGYAFERPALLGATIGRS
                     IGYGTDADEIQVRDAAVAAQVHDVLIRLPQGYETPMADAPLSGGEAQRVGLARAIIRDP
                     EVLVLDDATASLDTVTEAKVDKALTTALPGRTRVVVTHRPATAARADLVVWLEDGRVRG
                     TGTHQELWNDEDYRAVFTGGE"
     gene            14525..16243
                     /locus_tag="BM417_RS27150"
                     /old_locus_tag="SAMN04488564_107331"
     CDS             14525..16243
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030767.1"
                     /locus_tag="BM417_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107331"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_093600249.1"
                     /transl_table=11
                     /translation="MRFYLSTLAGHRRGVLILLGWSMLEGIPAFFGGRLVGTAVDQGFA
                     AGDPLAGVLWLLAFAALAVAGALGQRQVFARLGAVVEPMRDALVTRVVKGVLNDPSHRR
                     TPDASAVAMITRHVEVVRDATAGVLVQARALLVTTIAALIGLATTAAALIWLVVLPIVA
                     ALLLFGLMLPSLAKRQRDAVMADERTAEASGAVLTGLRDVAACDAAAEAYGDVAKQINL
                     QARATVTVAWANSLRATVIAIGGFTPVVLLVAFAPPLVASGQLTTGAVLAAVVYLTNSV
                     NPALHGLARTTSTVVMRLMVALKRLQEAAPRTGKEIGTEIPANGEFVLRDVTFGWSPDA
                     EPVLRGLSLDLRPGDHLAVVGPSGIGKSTMASLLTGLMPPDNGCVLFGGAPVDRVAPTV
                     RHHAIALIPQETYLFTGTVRENLTLLAPWATDEDLVDAVKKVGAKPLLDGLGGLDAALG
                     HGGEGLSAGEAQLLALARVYVTSAGVVILDEATSHLDPAAEARVERAFAQRNGILVVIA
                     HRLSSALRANRVLVMDGGKPLLGSHEHLLKTSALYGQLMLAWDPTHRKETPLPKR"
     gene            complement(16274..16777)
                     /locus_tag="BM417_RS27155"
                     /old_locus_tag="SAMN04488564_107332"
     CDS             complement(16274..16777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074684.1"
                     /locus_tag="BM417_RS27155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107332"
                     /product="DUF3145 domain-containing protein"
                     /protein_id="WP_030474501.1"
                     /transl_table=11
                     /translation="MSTRGSTSGVVYVHSSPSAVCPHVEWAISGTLGVRVDLRWAAQPA
                     APGQLRAECAWTGDAGTGAKLVAALRAWPMLRFEVTEEPSSGQDGERFCFAPVLGLWHA
                     RTSANGDIVVNEDQLRSLAVRARGGESFAHGVDELLGAAWDDALEPFRRAGDGAPVTWL
                     HRVG"
     gene            complement(16978..18318)
                     /locus_tag="BM417_RS27160"
                     /old_locus_tag="SAMN04488564_107333"
     CDS             complement(16978..18318)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153078.1"
                     /locus_tag="BM417_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107333"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_093600252.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 9.4e-44, bitscore:
                     144.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTRAALLAALLVAAASPVATAAPTSTVYVHGADITAAEQAVEAA
                     GLQKLTSFRKIGVVAARGDSAQISSARAKAGVTRVEVQKPIKFLGSTSHTATRGLDARN
                     SLGLTGAGVSVAVIDSGVDPNHPSFGGRIVRNLKSLCLDGSTQTNCIVPVPNFVDTDTT
                     SLGGHGTHVTGIAIGGDVQTTGGPVIHGAAPGAKGVVISTGAAILILGADAALNWVLEN
                     HQAPCGAGVPASTCPPIKVINNSYGPSGGGAFDPESVTVKLQRQLVAEGVVVVWANGND
                     GGDGSANLSNPPGIDPTPGVISVASYNDQETGTRDGAVSDFSSRGLATNSATWPDISAP
                     GENITSSCRLYLPICATGLKPQNGPGLLDLGTFNTISGTSMAAPHIAGIVAQLFQAKPS
                     ATPADIERALKSTAYKYGTGYGPVGPFTSSFDKGTGLVDVVAAVNAL"
     misc_feature    18372..18387
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    18433..18450
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            18462..19694
                     /locus_tag="BM417_RS27165"
                     /old_locus_tag="SAMN04488564_107334"
     CDS             18462..19694
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099001.1"
                     /locus_tag="BM417_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107334"
                     /product="hypothetical protein"
                     /protein_id="WP_093600254.1"
                     /transl_table=11
                     /translation="MRLIRLGAEPSAIGADVRAALTACGAGTQALGGVALIGVQPPDCP
                     MPLDAIVVLPKGVLVIVGVDLPDPALKLEAPLGGQWTIDGWPLVAQDGAPNPATEAVAA
                     ATAVAQRIQAMRAEPLPVSTVVAVGPFVDQVVQPTVDLNRGVRVLHPKPSTLLSAAREL
                     ATSTVPCTADHAVKLLAILQTTGTPPDARSLLSEGFSDAVSDLASANTMLIPKAAMRPM
                     LSRKRLPGKLTWPYLAVAAVVALILVGWLVVALPGDDKPADATPAPTSTQPTTVVVDGT
                     TFVPKEMKKDQDCQSQAFGDVKAWLIANDCGVLLRATYETSVQGKAATVLVADMDLYDA
                     PSAKSLHAVVVLPGSGGVHGLDGKPLENAAFANGTKGSHVTLAFAVWSGGAGDRTLDPI
                     AKQALRLPATR"
     gene            19707..20066
                     /locus_tag="BM417_RS27170"
                     /old_locus_tag="SAMN04488564_107335"
     CDS             19707..20066
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645186.1"
                     /locus_tag="BM417_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107335"
                     /product="VOC family protein"
                     /protein_id="WP_093600257.1"
                     /transl_table=11
                     /translation="MVGQLRSVVLDCPNPAELASFYEDLLGAERLPYGDDTWVVIVANG
                     TRLAFQLAPEYVAPVFPDPHASQQVHLDVVVDDVEKAEPKVLALGARLLQKDTGGWFRV
                     YADPVGHPFCLVWLS"
     gene            20252..21592
                     /locus_tag="BM417_RS27175"
                     /old_locus_tag="SAMN04488564_107336"
     CDS             20252..21592
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657578.1"
                     /locus_tag="BM417_RS27175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107336"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_093600260.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.3e-41, bitscore:
                     135.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFDVIVIGGGPVGENVAWRTAAGGLSTAMIEKELVGGECSYWAC
                     MPSKALLRSGHALAAAKRVKGVVGGSLDAAAVLERRTGFTSNWDDTGQVKWAESENIHV
                     IRGDGEVTGEREVTVGGEVYRARQAVVVCTGSVPKMPPLEGLADTPVWTSREATSAREV
                     PESLVVLGGGVVGVEMAQAWARLGSKVKLVVSGDRPLPRLEDFVGPLVVEGLREDGVEV
                     LLNGRASSIKPGELTLQDGRVVQGSHILVATGRVPATKDGKPLTIDDSGLVSGVDGRWL
                     YAAGDVTGRALLTHQGKYQGRAVGTAILERSRGFEPKQWSAGQAWADHVAVPQVVFTDP
                     EVAFVGHTAEEARAQGRDIKVVDLDIAVAGSSLHADGYKGKARMVVDERTRTLVGVTFV
                     GQDVAELLHSATVAIVGEVTVDRLWHAVPSYPTISEVWLRLLESYGL"
     gene            complement(21580..22206)
                     /locus_tag="BM417_RS27180"
                     /old_locus_tag="SAMN04488564_107337"
     CDS             complement(21580..22206)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800156.1"
                     /locus_tag="BM417_RS27180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107337"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_093600263.1"
                     /transl_table=11
                     /translation="MRRQPVQQRGAATVSAILDACASLLNEYDYDDITTARIVDVAGVP
                     IGSFYQYFPDKRSVVHALALRGMETYLREIEELFAADLIADTWRGAMTQIVAVYMRMLT
                     DVPGFGRVRFSDMLDSHRLDSSVDQYELMAERLAEMFVNRFGAHGDAPVMLTFRIAVQT
                     ADALFKLAERVDEDDRAYVIGTANELLTGMLGSVLEEPQDPIQSP"
     misc_feature    complement(22228..22244)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.58"
                     /tool="antismash"
     gene            complement(22301..22519)
                     /locus_tag="BM417_RS27185"
                     /old_locus_tag="SAMN04488564_107338"
     CDS             complement(22301..22519)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692718.1"
                     /locus_tag="BM417_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107338"
                     /product="DUF6343 family protein"
                     /protein_id="WP_093600266.1"
                     /transl_table=11
                     /translation="MSDYLPPPAPPRSALTLRLWLAGFGLVFNSVAGWLALRADLVWLG
                     ILLLLLAVVCLVDFGWVVHRKRRGDPG"
     misc_feature    complement(22373..22375)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 gaagtagacg ccgatcatcg cgaggtcgct gcgcggctcc tgggggtgct cgatcagccg
       61 cgtcacgcgc gagttctcgt ccacctccgc gacgccgtac aggcgcgggt cctccacctt
      121 gtccacgagc acctgcgcgg acggccgcag gcgggcgaac tcgtcggcga tctggccgat
      181 gccctcgacg agcacgttgt cgcccacgta catcacgaag tcgtcgtcac cgaggaacgg
      241 ccgggcgatc cgcacgcagt gtgcgagacc cagcgccacg tcctgctgga tgtaggtgat
      301 cgagacaccc aggtacgcgc catcaccgaa cagctcggag atctcctgcg cgccgtcacc
      361 cacgacgatg ccgatgtcgg tgatcccgac gtcccgcagg ttctccacga cgtactcgag
      421 caccggcttg ttcgcgatgg ggacgatctg ccgtggcagc gagtatccgg ccgggcgtac
      481 gcccgcggac agcacaaggg ctttcatagg tcctccaccg cgacggaaca gttcgggtgg
      541 atacgaggct gcggccgggc actggaccga aactggagaa ctgtcagaac accagaaagg
      601 ggccctacgc aagatgtttg cgcagggccc cttccaggag gtgagaacta cctctcagac
      661 atcggagtgc ccgacggagg cgtctgcatg tcacccatgc ggccgccgac gttcgccggc
      721 atctcctgcg acgcacgcgg catcggcgac tgggcctgcg cctcgtcctg cacgcgggtc
      781 agccagccct cccagcgctg ctgcatcggg cggaccaggc cgccacccac accgatgacg
      841 atcacgccgg cgacggtggc gagcacggcg atcaggaccg gcatggtcac cgagatcgcg
      901 atgcccagct ggttgagcgc cgcgatgatg ccgagcgcca tcacgaagcc gtaggtgatg
      961 ttgcccatga gcttcgtgta cgtgcgctgg cccagcgcac cggagacgag acccttgagc
     1021 gccgtgccga tggccgatgc gacgatcacg agcaccagcg ccacgacgat gcgcggcagg
     1081 tacgcgatga cctcgttgag cagcgtgctg accgggttcg aggcgccgaa gacgccgaac
     1141 gccagctgga gcgcgatgag cagcacgaag tagtacacga tcttggcgat caggccggac
     1201 gcgtccatcg acgactgccg catggcgccg gtgaggcccg acttctcgac gagcttctcg
     1261 aagccgacgc gcttgagcag gaactggacg cccttggcga gcgccttcgc gatgaaccag
     1321 ccgatgacca gaacgagcag gaagccgagc agcttcggca cgaacgtggc gatcatcgcc
     1381 cacgcctggc ccaggccctc ggtgatttgc gagcccacgg gccctcctag aacaaagttg
     1441 cggtgagtga agatcagacg aggtgatcgt ttcgtggatc acaccgctcc acaacttcga
     1501 caccgctaca cgaaagggtg gctgacgtgg atttttgtcg caatacagtc cagagtggaa
     1561 ccaccggtgg ggaccgggga gagggaagcg cccgccacgc tccgtggcgg gcgcttccac
     1621 atttctacgg tcgtgcggag agccctcggc cgtcgaggta ggcctggatc ccctcgggtg
     1681 acaacgccgg cgccgcgccg ccctgaccgt ccttcggcac gtccggccgc gggtcaccgg
     1741 tgcactcgga actgctgccc ggcagcgccc cgtcgatcag gtaccggttg accttgtcgt
     1801 cgacgcactt gttgcccccg ttgtagaggc cgtgcttgcc ctcgtcggtg acggtgatca
     1861 ggttgtgccc gagccgctgg gccatcgccg ggccgctcgc gtactgggtc tgcgtgtcgc
     1921 cctcggactg cacgacgacg ccgatcgggt agccgttgcg gccgatcctg accgccggct
     1981 ccggcggcgt gaacgagcgg aacgtgcagg tcatcggcgc ggccctgacg atgccgaagc
     2041 cgtacgggta gcgctcgcgg aacatgcgca tgtcctcgta gtagacgtgc aggtcggtcg
     2101 gccagtccga ctcgcaggtg accgtgtcga acacgcccga ccgcagctcc tccagcccgg
     2161 tcttggcgag cacctgaccg gccttggcgc cctcggcgtt gtccggcttc tcccccgacc
     2221 ggagcttggt cacgatcgcc gccaggtccg accacagtgg acggtagcgg gcaccgacac
     2281 ccgttgcgcc gtcgaaggaa gagcggttgt gctcaccgat cggcgtcgcg tgcagcttcg
     2341 cggcgacctt ctcgacctcg gccagcacct cgtcgcgtga cttgcccagc ccgaacttct
     2401 cgttgcgctc ccccacccac gccgcccacg cctcgacgtc catccggtac gccacggcct
     2461 gctggcggaa ctgctcgtgc cagatccact ccgggtgcac ggccgagtcg agcacgctgc
     2521 ggtcgagccg gttcgggaac aacgtcccgt acaccgcgcc caggtacgtg ccgtaggagt
     2581 aacccaagta gttgatcttc tgctcgccca gcacggcgcg cacgacgtcc atgtcccgcg
     2641 cggtgttcgc ggtgctgatg aactgccgga tcccgccgcc cgacttctgg caggcctcct
     2701 cggcctcgcg cgcctcggcg gcccacttgc cgaactcgcc gtccgcgggc cgggactccg
     2761 gctcggcgat cgcgggcgcg gtgcggcagt tcagcgccgt cgaaccaccg acgccgcgcg
     2821 ggtcgatgcc gatcacgtcg tagacctgcg agagttcgga cttcgccagg aacaacggca
     2881 ggccgaggcc ggaaccgcca ggtccacccg gattggtgaa cagcacgccg cgcctgcggt
     2941 cggccgccac cgccttcttg cggctgatcg tcaggttgat cctgtcgccg ccgggtttgg
     3001 cgtagtcgag cggcgcgacg agcgtggcgc attccagttc agcgagcttt ccgctgcacg
     3061 gcgcccactt caccggttgg gcgtggaact cggcgagagg gtcgggagga tcggccgcgg
     3121 cggtcacgcc cgtcgtcagc aacgccacca cgctcagggc aagggccggg aacctacgca
     3181 agacgaacct ccgcgccgca ctgaaagatc tctgccgccc gacggtatgg ccgcgcaaac
     3241 agccacatgg gttgtgtcac ccatcccggt gatgtcccct cctgagccct aagctgcggg
     3301 tatgaccagc agcaaggcga aggaggagca cccgcccacg ctctccgccc gcacgatgcg
     3361 caagatcgaa cgcgcgtcgg gttcgctcgc caccgccagc gtggccgaga tggaacggcg
     3421 gctgtcgtgg ttcgcgcgaa tgcccgcgga ccagcgcgcg agcgtgctgc tgctgatcca
     3481 gaacggcgtg gccgggttcg tcgagtggct gcacgaccgg cagcaggcga tccggctcac
     3541 cgcggacgcg ttccgcagcg cccccaagga catctcccgc tgggtcagcc tgcgccagac
     3601 cgtggaactg gtccggatag cgctggaact gttcgaggag cagatgccgc agatggcggc
     3661 ggacgaggcg gagcgcgcgc tgctgatgga aggcgtgctg cggtacgggc gggagatcgc
     3721 cttctcggcc gccacctcgt acgcgaccgc cgccgaggcg cgcggcgcct gggacgcacg
     3781 gctggaagcg ctggtcgtgg acggcatcgt gcgtggcgac cccgaggagt cgctgctgtc
     3841 ccgcgccgcc gcgctcggct gggacccggc gatcgaggcg acggtgctgg tcggcaaccc
     3901 cggcggcgag gaccctccga cgatcatcta ctcggtgcgc agcaaggccg cccgcgcggg
     3961 caggccggtg ctgctgtccg tgcagggctc ccggctcgtc gtcgtgctcg gtggcccgac
     4021 cgagacaggc gacgacgtgc tgggccgcat ctccgagggc ttcggcgagg gccccgtggt
     4081 cgccggaccc accgtgacca acctttctga ggctcatcgc agcgccagcg acgcgctgag
     4141 cggcctgcgc gcggtcgtcg gctggcccgc cgcgccccgg cccgttcggt cgctggacct
     4201 gctgccggaa cgggcgctgg ccggtgatcc ggaggccgag tggcagctcg tcgacagggt
     4261 cgcgcggccg ctggaggacg ccggcggggc gctgctggag accgtggacg ccttcctgga
     4321 ggtcgggggc gtgctggaga cgtgcgcgaa aagactgttc gtgcacccga acacggtcag
     4381 atatcgcctt cggcgcgttc aggaaatgac gggaagaaat gcacatgacg ctcgagacgc
     4441 gcttgtgctt cgcgtcgctt tgtctgtagg acgccttgct cgcgcccggg gcctgtggta
     4501 gccgaacggg ctgtgacgga cttcgcacac atccgttagg gtgagggcca aacgaccccc
     4561 caccgcgctg agctgggctt acgtcgcgga gcgttcacct ggcagacact tttgtagggt
     4621 ctctacaaat acgatcgcag tacttcgttc tttacagcat ggggtaccgg tgggttcacc
     4681 agctttagta atcgacgtga tcgcactcct cgcgcccgga caagggtccc agacgcccgg
     4741 catgctcacc ccctggctcg aactggaggg ggccgagaag caggtccggg cgtggtcgga
     4801 gatcacgggc ctcgacctcg tgcgtctcgg caccaccgcg gaggctgacg agatcgtcga
     4861 caccgcgatc acccagccgc tcgtcgtggc tctcgcgctg ctcgcgttcg gtgagctgcg
     4921 ccgccgcgtc gaactgccct ccgccgtgat cgtcggcggc cactcggtcg gcgagctcgc
     4981 cgccgcgtcg gtcgcgggcg tcatcagcgc cgacgacgcc gtcgcgctgg ccgccgtgcg
     5041 cggtgccgcg atggccgagg cctgcgccca ggagccgacc ggcatggccg cggtgctcgg
     5101 tggcgacgag ccggaggtgc tcgcgcgcct cgaggagctc ggtctcgtgc ccgccaaccg
     5161 caacggcgcc ggccagatcg tcgccgccgg tccgcgtgcc gcactcgacg agctcgcgga
     5221 gaaccctccg ggcacggcga aggtccgcaa gctggccgtc gcgggcgcgt tccacaccaa
     5281 gtacatggcg ccggccgaag acgccgtgcg cgcgcgtgcc gccgaagtca ccacgcacga
     5341 cccgttgctg ccgctgctgt ccaacaagga cggtcaggtc gtcaccgagg gcaccgaggt
     5401 cctgcgccgc ctggtctccc aggtcacgag cccggtccgc tgggacgtct gccaggccac
     5461 cctcgtcgag aagggcatcg ccggctcgat cgagctgccg cccgccggcg cgctcacggg
     5521 tctcgccaag cgtgcgatga agggcaccgc caccctcgcc ctgaagaccc cagaccagtt
     5581 cgagaaggtc gcggagctct tcgacaccgt tggagccgat aagtgacgac cttccaggcc
     5641 ccgcacgcgg ctgcgggtag ccgcatcatc ggtctcggca gctaccagcc cgagacggtg
     5701 gtgagcaacc acgacctcgc ccagcgcatg gacacctcgg acgagtgggt ccgcgagcgc
     5761 gtcggcatcg tcaaccggca cgtggcggcc aaggacgagg gcgtcgtgga catgtccgtc
     5821 gcggcgggca ccaaggcgat cgcggacgcg ggcctcaccg cggccgacat cggtggcgtg
     5881 atcgtggcga cgtgcaccat gccgtcgacc atcccgaacg ccgccgcgca ggtcgccacc
     5941 cggctgggca tcaaggccgc ggccgcgttc gacctgaacg ccgcgtgcgc gggcttctgc
     6001 tacgccgtcg cgaccgccgc ggacatcgtt cgcggcggcg cggtgaagaa cttcctcgtc
     6061 atcggcgcgg agaagctcac cgactggacc caccccgacg accgctcgac cgcgatcatc
     6121 ttcgcggacg gcgcgggtgc cgtcgtcgtc ggtgccagcg acgagaacca catcggcccc
     6181 gtcgcctggg gctcggacgg ctcgatgtcc gaggtcatca ggatcgacga ccgcgactcg
     6241 ttcatccacc aggaaggcca gacggtcttc cggtgggcga cgacccagat cgcaccggta
     6301 gcgctccgtg ccgccgaact cgcgggtgtc gaactgtccg aagtggacgt gttcgccccg
     6361 caccaggcca acctcaggat catcgaggcc atcgccaagc gcctgcgcaa caatggtgcg
     6421 cgcgaggacc tgaaggtcgc tcgagacatc gtcgaatccg gcaacacctc ctcggcctcg
     6481 atccccatgg cgctggacca catgaggtcg gcgggcgaga tctcctccgg agacgtggtg
     6541 ctgatggtcg ggttcggcgc tggcctgtcc tacgcgggcc aggtgatccg gtgcccgtga
     6601 gcaccacccc gagtttttcc atcgtttcaa tcgaaaggga acttcagtga gcgacaacgt
     6661 cctgtccggt cttgccgaga tcgtcgaaga ggtcgccggc gttgccgccg acgacgtcac
     6721 cgctgagaag tccttcgtgg acgacctcga catcgactcg ctgtcgatgg tcgagatcgc
     6781 cgtccaggct gaggacaagt tcggcgtgaa gatcccggac gacgagctgg ccaacctcaa
     6841 gaccgttggt gacgcggtga actacatcac cagcaacaag tgagttcggg catcgaggtc
     6901 gtcatcaccg ggctgggtgc caccaccccg ctcggtggtg atgtcacgtc cacctgggac
     6961 gcgcttctgg caggcaagag cggggtcggc cccatgaccc acgagtgggt cgcgaagtac
     7021 gacctgcctg tcaagatcgc gtccgagctc gtggtggacc cgaccgaggt gctcccccga
     7081 gtggaagctc gacgcctgga ccgctccgag caggtcgcca tcgtggcgtc ccgccaggcg
     7141 tggtccgacg cgggacacaa cgacgacacc gtcgacaaac agcgcctcgc cgtgatcatc
     7201 ggcacgggca tcggcggcgc gatcaccctg ctgacccagg acgacctcct ggagcagcac
     7261 ggcctgcgca aggtgtcgcc gctgaccgtc cccatgctca tgccgaacgg accggccgcg
     7321 cacgtgggcc tggaactgaa ggcacaggcg ggcgtgcacg ccccggtctc cgcctgcgcg
     7381 tcaggcgcgg aggccatcgc gtgggcctac cgcatgatca tgtccggcga agccgacgtg
     7441 gtcgtggcag gcggcgcgga agcgtgcatc acggcgatcc cggtcgcggg cttctcgcag
     7501 gcccgcacca tgagcacccg caacgacgag ccggagaagg cctcgcgacc gttcgacacg
     7561 gcccgcgacg gcttcgtcct cggcgagggc gcgggcgtca tggtcctgga acgccgcgag
     7621 ttcgcagagg cccgcggagc caagatctac ggccgtctcg ccggtatcgg cacgtcggcc
     7681 gacggctacc acatcaccgc cccggacccc gagggcgtcg gccagtcgcg cgccatcgcc
     7741 gcagccctgc gctccggcgg catcgacccg tccgacgtcg gccacgtgaa ctgccacgcc
     7801 acgtccaccc cggtgggcga cgtcgcggag accgtggcga tccgcaaggc gatcggcgac
     7861 cacccggtcc tgaccgcccc gaagggctcc ctgggccacc tgctgggagc agcaggcgcg
     7921 gtcgaggcca tcatcaccgt cctctcgatc cgcgacggca tcgttcccca gacgctcaac
     7981 ctggagaacc tcgacccggc cgtcacgctg gacgtggtgg cgggcgaacc ccgcaagatc
     8041 aagctggacg ccgcggtgaa cgactcgttc gggttcggcg gccacaacgt ggccctggcc
     8101 ttcaccccgg cctaagcacc accgttccac cgcacgcccc ggtccgccca gcggcccggg
     8161 gcgttgcgct ttcccggcca gggattcggc acgctcgcgc aggggtcccc ttggattcag
     8221 cgtccccgcg acccaacgta gcgagcgggt ctgacagtcc cgcgaggacg agagcgagag
     8281 ccggagcgag cgtggggcaa cgcgggagca gggggagcag agcggggagt gatgcgaggc
     8341 gcggagcggg cgaggcgagg gtgggaccga gctggcagcc cgcacgccca cccgatcgca
     8401 gatcgcacgc gatgccgaag gcgagccgtc cttaccgcgc ggtcagggtg gggtggtccc
     8461 gtcacgagtc gcacctcagc acttgctgca tctgaggagg aggggcaagt cgacacgctt
     8521 ttcgtcgact tgcccctcct cctcagatgt ggcccgctcg ggtgcgactc gtgacgggac
     8581 caccccacca acgcacccca gctacgcaac gcgcctccgc ccaacgcaac aggcgtgcca
     8641 tcaacctgcg cgtggcgtgg gccggtcttt gatcagattg tgggggtctg ggggcggagt
     8701 ccccaggaag cagcagccac acccgcactc aacgcaccca cctacgaacg acaaaccgcc
     8761 gcccgccaac gaaacagggg gacgacctac gcaaccgacg cgccaacgcc gaaggcgagg
     8821 cgcctcagca cttctccatc tgagggttcc ggttctccgc ggcctcatcc accttcaaaa
     8881 ccccaccctc ccagaccaac acataaacca cccgccaccg aatacaccct tcaggcaacg
     8941 caggcggagc cttggcaaca tcctgagtgg acacgaacga gatcaacgcc cgcagccgcc
     9001 gagcaaccac atcggactcg atccgctgca ccaccatccc gccgtcctca gtggtctcgt
     9061 aagccgcgac ccaggaagcc tcaggcgtgg acgaaacccg ccgagccgac accaccccgc
     9121 gccaggcatc gaagtcccgc gagttgatcg cgtcgaagta ggcctgcaac acccgctgca
     9181 cagccgtccg atccggatgc gtgaacgagt ccgggctgag ccggacctcc gcggacccgg
     9241 gcaccggccc cgcgacggac gaggacgcga ccacgggcgc ccccttggcc tcggccggac
     9301 gcgagtacac ggtccggccc accattcctg ccgccaccgc ggcaccggtg atcaccacca
     9361 cggccggcac cagccagcgg cttgccacgc tccccacacg cgcagcctag ccgcacggca
     9421 cgccggggag cagagggccg ctcacaaaac gtgtctcgtt acaacaaaac acggatttca
     9481 ctcgaacgat tacatcacat agggatttgc ccagttgcat gtagcaagac aatgtttgat
     9541 acataaaaag tcggtgccca atctcatcct acgaatgggt tcctacgggc tacgccatac
     9601 cgccgttcgg ccgtatcaaa cacgcaatgg cagccaattt ttgcttcact cgtaaagagc
     9661 aaccgacaca gcgcgtacac gacgtttgca cacacctaac tatacgtcgg gatcgaactg
     9721 gaataccgca gctcagaggc acccatgatc aggaacgcct cggtgccgtt tagcgaaaac
     9781 gcgggatacg ccggacaaac cgtccggcag caaacatctc aaccgggtga gacggaccca
     9841 aacctcatga ctcgacgtca catacgcacc ggtaaccgat gttctttcgg acacgaacgg
     9901 ggtacccata tgaccctaac ggcggattcc ccatagcctc gagattgtgc ggaaatatgc
     9961 ggcatcaaag aaacgaaaac gagtcaggga ggggaattcg gtggacctca gatacgaggc
    10021 gtactgcttc gccgatcggc agttctacga tctgcagagc agcaccgaaa gcactcccaa
    10081 ggacgacttt tccaccgaac tccccgcgct cccacccgac tgggcgacgg ttgagcgcaa
    10141 cgtgtggcga caccaccacc cgatgggggt acagcttccc aaccaagggt ggaaaatcca
    10201 cgtttccgct ggactcgaca acgccggccg ggtactgaag gccacttacg actattgcgt
    10261 cgagcggcgc atcagtttca agtacctgca gacgatgtcg atcgtgctgg cgcgaaactc
    10321 gaagtacgcg ccccgtgagg gcagcggcaa gctggtcacg atctacccgc tcgactccgc
    10381 gcacctcgaa gcgatcctca ccgggctcgc ccacgtgctc gaaggcgagc acggcgcgta
    10441 catcctgagc gacctgcggt tcggcaaggg gccgctgtac gtgcgctacg gcgggttcgc
    10501 cgagcagtgg ctggaggtcg acgggcagca ggtgctcgcg atcgaagggg ccgacggcac
    10561 gctcatcccg gacaggcgca agcccgtctt cagcctgccc gagtggatcg agctgccggc
    10621 gttcctcaag ccgcacctcg ccgagcgcaa cgccggtgac ccggcccggt tccagtacca
    10681 gatcaagagc tcgctgcact tctccaacgg cggcggcgtc tacctcgcga ctcggaagtc
    10741 cgacggcaag gaggtcgtgc tcaaggaagc gcggccgcac gccgggctcg accgcgaggg
    10801 cgaggacgcg gtggcacggc tggaccgcga gtacgagatc ctgacgaagc tccagggcat
    10861 caagggcgtg ccggaggtgt acgaccgctt caccgagtgg gagcacctct tcgtcgccat
    10921 ggagttcatg cccggccgct cgctcgggca gtggctcggc aggcactacc cgttgacgca
    10981 caaggacgtc agcgacgaga cgatcaccga gtacaaggca cgcgcactcg ccatggtcga
    11041 ccgggtcgag agcctgatgg ccgaggtcca cgagcgcggc gtcgtgttcg gtgacctgca
    11101 cacgctcaac atcctcgtgg acgacgagga cgagatctcg ctcatcgact tcgagctgag
    11161 ctcgacgatc gacgccgtcc gcaagcccac gctcggcgcg ccggggttcc aggcgccgcg
    11221 ggaccgcgac gggttcgaca tcgacgcgca cccgctcgcc gctctccggc tctggatctt
    11281 cctgccgctc aacacggtgc tggaactcgc gccggccaag atcaggcagc acgtcagggt
    11341 catccagcag cgtttcgggc tcaccgacga gtactgcgcg ccgatcgtcg acgtgctgac
    11401 cccgcgggtc gaccctccga cggacccggc gttcaccgag ttcgacgagg agacgccgga
    11461 ctgggcgttg gtgcgcaagg agatcgccac ggcgatcctg cacagcgcca cgccccaccg
    11521 ccaggaccgg ctgttccccg gcgacatcga gcagttcgag accggtggcg cgggcttcgg
    11581 gtacggcgcg gcgggagtgc tgcacgcact cgcggagtcc ggcgagggcc gcttccccga
    11641 gcacgaggag tggttgctcg acgcgctcag gaaagacccg ccgaagcagc ccggtttcta
    11701 cgtcggtgcc cacggcatcg cgcacgtgct ggagaacttc ggccaccacg acgccgcgac
    11761 cgagatcgtc gagagctacg ccgagctcgt tccgtccact caggaccacg gactgagcgc
    11821 gggcctgtcc ggcataggcc tgaacctgtt gcacttcgcg aactcccgcg aggacgacag
    11881 cttcgcggcc caggccgagc acctcgcgca acggctcgcg aagcagctcg cggacgcgcc
    11941 gggcccggcg gacaaggcga aggcgggcct gctgcacggc tggtccggac cggcgctgtt
    12001 cttcctgcgg atgttcgagc acaccggtga acgccgctgg ctcaagctgt ccgagcaggc
    12061 actggaacgc gacctggccg agacgatgat cgcgctcgac ggttcgttgc aggtgcgcga
    12121 cggcacgctg cgaagccttc cgtacgtggg catcggcggc gccggcatcg ctctcgtgct
    12181 gaccgagttc gcccagcagg cgccggaacg gccgtgcgtc gagaagctgc ccgaactgct
    12241 caccggctgc accggcgagt tcgtcatcca gcccgcgttc acgctgggca gggccggact
    12301 gctcgccacc ctggcgcacg ccacgcgtca ccggccgaac gagcgcttcg agcgcgccat
    12361 cgggcagcac ctcaaagccc tgggctggca cgccacgcgc tacggcggcg ggctcgcgtt
    12421 ccccggtgtg cagctgcgcc ggctctccat ggacctcaac accggcggcg cgggcgttct
    12481 gctcgccctg gcgtccacag tggacggccg tgcaccactg cccttcctgg gctcacgaac
    12541 gccggtcctc gcggaccggt agcagtaaag agatcgatcc ctcgaaacta ggagatagcg
    12601 tcatgggctt catccttgac atgcaggacc tcgagacgcc cgaggccccc gccaacatga
    12661 tggccggcgg ttccggtggt ggcggcggcg gttcgaccac cgcgtcgagc gcctccctgc
    12721 tgctcccgtg cagccacagc agcgcgtccc tgctgctgtg ctgatctggc ttcaccagca
    12781 cgtgatcggc cggtgagcgg cataggcgaa gtatgccgct cacccgcctg aagaggggct
    12841 cggcagccgg ccagctgtcg ggcccctcgc ttcatgatgg gcccagatga gcctcggagg
    12901 aacagccgat gaccaaaccc ggtgaccagc tgttgttctc caccgtcaaa cgcgactacc
    12961 gcccgtggtt gctgcttctc aacgccgccg tcgccacgac cggcggcctt ctgcttcccg
    13021 ccgccctcgc cggggccgtc gacatggccc tgagcggcac gttcgtgctg gccacgatcg
    13081 tgttcctgct ggtgctggcg ggtgtcgaga tcctcggcga cgcgatcggc atcatcctcg
    13141 ccgcgagcat caccgcccgc gccacggcct ggctccggcg ccgcctgacc cggcgtttgc
    13201 tcactctcgg tcacccgtca ccgttcgccg caggggacgc cgtcagccgc gtcaccggcg
    13261 actgcggcaa cgcgggcagc gtcgcggtga ccgtgatcag tctcgccgtc accgccgtgt
    13321 cgtcggtcgg ctcggtgatc gcactggccc ttctggactg gcggctcgcg gccgtgttcc
    13381 tggtgagcgc ccctctcgcg ggctatctcg tccgcacgca catgcgcctc accgccgacg
    13441 acgtcctggc gtaccaggag gtgtccggcg aggtgtccgc gcggctgctc gactcggtgt
    13501 ccggcctgcg cacgatcgcc gccgccggca tcgccgatcg cgagacgaac cgcgtgctgg
    13561 agccgctccc ccggctcgcc gcggcgggcg ccggcatgtg gcgcacccag gcgaagatga
    13621 tgtggcgggc cgggttgttg ctgcccgccg tcgaggtcgc ggtgctcacc gccgccggtt
    13681 tcggtgtgat ggaaggcagg ctgagcaccg gtgacgtgct cgccgccctc gggtacgcgg
    13741 cgctcggcat gggcatcgtc ggccagatga cccagctgac cgtgctggaa cggacccgcg
    13801 ccagcgccgg caggatcgcc gaggtcctcg acaccccggc accgaaacgc ccagccccga
    13861 agccgtccaa cggagtcatc gaactccggc acgtcagcgt cggcgacgcg ctgcacgacg
    13921 tgaacctgat gatcccggcc ggcacgttcg ccgcgatcgt cggcagttcc ggcgcgggca
    13981 agtcgacgct ggccgccgtg ctcggcggac tgtccgctgt ggacgcgggc gaggtggtgg
    14041 gagacgacgc ggtcggatac gccttcgaac gccccgcgct gctcggcgcc acgatcggtc
    14101 gttctatcgg ctatggaacg gacgccgacg agatccaggt gcgcgacgcc gccgtcgccg
    14161 cccaggtgca cgacgtgctg atccgtctgc cgcagggata cgagacgccg atggccgacg
    14221 caccgttgtc cggcggtgag gcgcaacgag tcggcctggc ccgcgcgatc atccgggatc
    14281 ccgaggtgct cgtgctcgac gacgccaccg cgagtctgga caccgtgacc gaggccaaag
    14341 tggacaaggc gctcaccacg gcactgcccg gccggacccg cgtggtcgtg acgcaccgcc
    14401 cggccacagc cgcgagagcg gatctcgtgg tgtggctgga agacggccgg gtccgcggca
    14461 ccggcaccca tcaggagctg tggaacgacg aggactaccg cgctgtgttc accgggggcg
    14521 agtgatgcgt ttctacctct ccacgctggc aggacaccgc aggggcgtcc tgatcctgct
    14581 cggctggtcc atgctcgaag gcatcccggc gttcttcggt ggcaggctcg tcggcaccgc
    14641 cgtcgaccag ggcttcgcgg caggagatcc gctggccggc gtgctgtggc tgctcgcgtt
    14701 cgcggcgctc gcggtggcgg gcgcgctcgg ccagcggcag gtgttcgcac ggctcggagc
    14761 cgtcgtcgaa ccgatgcgcg acgccctggt cacgcgggtc gtgaagggcg tgctgaacga
    14821 cccgtcgcac cgccgcacac cggacgccag cgcggtcgcc atgatcaccc ggcacgtcga
    14881 ggtggtccgc gacgccactg cgggcgttct ggtgcaggct cgcgcacttc tggtcacgac
    14941 gatcgccgcg ctcatcggtc tcgcgaccac ggccgccgcg ctgatctggc tggtcgtgct
    15001 gccgatcgtg gcggcgctgc tgctcttcgg gttgatgctt ccctcgctgg ccaaacgaca
    15061 gcgcgacgcc gtcatggccg acgaacgcac ggcggaggcg tccggtgcgg tgctgaccgg
    15121 actgcgtgac gtcgccgcct gcgacgcggc cgccgaggcg tacggggacg tcgcgaagca
    15181 gatcaacctg caggccaggg ccacggtcac ggtcgcgtgg gcgaactcgt tgcgcgccac
    15241 ggtgatcgcg atcggcggct tcacgcccgt cgtgctgctg gtggcgttcg ctcccccgct
    15301 ggtcgcttcc ggtcagctca ccacgggtgc cgtcctggcg gcggtcgtct acctgaccaa
    15361 cagcgtgaac cccgcgctgc acggcctcgc ccgcaccacc agcaccgtcg tgatgcggct
    15421 gatggtcgcg ctcaaacgac ttcaggaggc cgcgccgcgc accggcaagg agatcggcac
    15481 cgaaattccg gccaacggcg agttcgtgct gcgggacgtc acgttcggct ggagcccgga
    15541 cgcggaaccg gtgctgcgcg gcctgtcact cgacctgcgt cccggcgacc acctggcggt
    15601 ggtcggcccg tccggcatcg gcaagtccac aatggccagt ctgctcaccg gtctgatgcc
    15661 accggacaac ggctgcgtcc tgttcggtgg cgcgccggtc gaccgggtag cgccgacggt
    15721 caggcaccac gcgatcgcac tgattccgca ggagacgtac ctgttcacgg gcactgtgcg
    15781 cgagaacctc acgcttctcg cgccgtgggc gaccgacgag gatctcgtcg acgcagtgaa
    15841 aaaggttggc gccaaaccac ttctggacgg actgggtggc ctggacgccg cgctcggcca
    15901 tggcggagaa ggactttccg ctggtgaggc gcagcttctg gcactcgcgc gggtctacgt
    15961 cacgtccgcg ggcgtcgtca tcctcgacga ggcgacctca catctggatc ccgccgccga
    16021 ggcccgggtc gaacgggctt tcgcgcaacg gaacggaatt ctcgtggtga tcgcgcaccg
    16081 gctgagctcg gctctgcgag cgaaccgcgt gctggtcatg gacggcggca agccgttgct
    16141 cggctcccac gaacacctgc tcaagacgtc cgcgctctac gggcagctca tgctggcctg
    16201 ggatcccacg caccggaagg aaaccccgct gcccaaacgg tgagcggggt ccacacagga
    16261 ctaaacagtc ccgttagccg acacggtgca gccaggtcac cggagcgccg tcgcccgcgc
    16321 gacggaacgg ttccagcgcg tcgtcccacg cggcgccgag cagctcatca acgccgtgcg
    16381 cgaaggattc gccgcctctg gcacgtacag ccagtgaccg cagctggtcc tcgttcacga
    16441 cgatgtcgcc gttcgccgac gtgcgggcgt gccacagccc caaaacgggc gcgaagcaga
    16501 agcgctcgcc gtcctgaccg gaggacggtt cctcggtcac ctcgaacctg agcatgggcc
    16561 acgcgcgcag cgcagccacg agtttggcgc cggtgccggc gtctccggtc catgcgcatt
    16621 cagcgcgcaa ctggcctggt gccgcgggtt gcgctgccca cctgaggtct acccggacac
    16681 cgagggtgcc cgagatcgcc cactcgacgt gcggacagac cgcagacggc gacgagtgga
    16741 cgtaaaccac gccactggtg ctgccacggg tgctcactgc tgacctccgc tactcgacga
    16801 gggacgtctt cccctacgcc tttgtcgaga gtgaggtgat caccgcgaaa cccgttcgct
    16861 gcattctgcc tcgacttgag gcatgtccgc cataagaacc agctcgatca tcacccgacc
    16921 ggggcagata caggtcttaa gtcccgatct cccggccgag tgatgcctga tcgtgatcta
    16981 cagagcgttt accgcggcca ccacgtcgac tagacccgtc cccttgtcga acgacgaggt
    17041 gaaggggccg acgggcccgt aaccggtgcc gtacttgtag gccgtcgact tcagcgcccg
    17101 ctcgatgtcg gccggggtcg cggaaggctt ggcctggaac agctgtgcga cgatcccggc
    17161 gatgtgcggt gccgccatcg acgtgccgct gatcgtgttg aacgtgccga ggtcgagcag
    17221 tccgggcccg ttctgcggct tcaggccggt cgcgcagatc ggcaggtaga gccggcacga
    17281 cgaggtgatg ttctcccccg gcgccgagat gtccggccac gtcgcggagt tcgtggcgag
    17341 accacgggac gagaagtccg acacggcgcc gtcgcgagta ccggtctcct ggtcgttgta
    17401 ggaggccacc gagatcacgc cgggcgtcgg gtcgatgccg ggcgggttcg acaggttcgc
    17461 tgaaccatcg ccgccgtcgt tgccgttcgc ccacaccacg acgacgcctt cggccacgag
    17521 ctgtcgttgc agcttgacag tgaccgactc agggtcgaac gcaccgccgc cagatggccc
    17581 ataggagttg ttgatcacct tgatcggcgg gcaggtcgag gcgggcacgc cggcgccgca
    17641 cggggcctgg tggttctcca gcacccagtt cagcgcggcg tccgcgccga ggatgaggat
    17701 cgccgcgccg gtcgagatca cgacgccctt cgcgcccggc gccgcgccgt ggatcaccgg
    17761 tccgccggtg gtctgcacgt cgccgccgat cgcgatgccg gtgacgtggg tgccgtggcc
    17821 gcccagcgag gtcgtgtcgg tgtcgacgaa gttcggcacc ggcacgatgc agttcgtctg
    17881 cgtcgagccg tccaggcaca ggctcttcag gttgcggacg atccggccgc cgaacgacgg
    17941 gtggttcggg tcgacgcccg agtcgatcac cgcgaccgac acgcccgcgc cggtcagccc
    18001 gaggctgttg cgggcgtcca ggccgcgcgt ggcggtgtgc gaggtcgacc cgaggaactt
    18061 gatcggcttc tggacctcga cgcgcgtcac gcccgctttg gccctggcgg aggagatctg
    18121 cgcggagtca ccccgcgcgg ctacgacgcc gatcttgcgg aagctcgtga gcttctgcag
    18181 accagccgct tcgaccgcct gttccgcggc ggtgatgtcg gctccgtgga cgtagaccgt
    18241 ggaggtcggc gcggccgtcg cgacagggga tgcggcggcc accagcagtg cggcgagcag
    18301 tgcagcgcgt gtgtacatgg accctccgtg aacattggca ggcaatccat ctaacgagtg
    18361 atccacttat cggtgacggc catcacgcaa tgtctcgacc ggctgcgttg ggacgacccc
    18421 ggaccgctac ggtgtccccc cgtgcggaaa ggtagggact cgtgcggctg atccgtctgg
    18481 gcgctgaacc ttcggccatt ggggcggacg tccgtgccgc cctcacggcc tgcggcgcgg
    18541 gtacccaagc tctgggtggc gttgcgctca tcggcgtgca accacccgac tgtccgatgc
    18601 cgctggacgc gatcgtcgtg ctgcccaagg gcgttctcgt gatcgtcggt gtcgatctgc
    18661 ccgaccccgc gctgaagctg gaggcaccgc tcggcggtca gtggacgatc gacggctggc
    18721 cgctggtcgc ccaggacggc gcgcccaacc cggcgaccga ggccgtggcg gcggcgaccg
    18781 cggtggcgca gcggatccag gcgatgcgcg cggaaccgct cccggtgagc accgtcgtgg
    18841 cggtcggccc gttcgtggac caggtcgtgc agccgacggt cgacctcaac cgaggcgtgc
    18901 gggtgctgca ccccaaaccg tccactttgc tcagtgcggc ccgtgagctc gcgacctcga
    18961 cggtgccctg cacggccgac cacgccgtga agctcctcgc gatcctgcag accaccggca
    19021 cgccaccgga cgcgcggtcg ttgctctccg agggcttcag cgacgcggtg tcggatctcg
    19081 cgtccgccaa cacgatgctg atccccaagg ccgcgatgag gccgatgctc tcgcgcaaac
    19141 gcttgcccgg caagctgacc tggccgtacc tcgcggtcgc ggcggtggtc gcgctgatcc
    19201 tcgtcgggtg gctggtggtg gcgctgcccg gcgacgacaa gccggccgac gcgacgcccg
    19261 cgccgacctc gacgcagccg acgacggtgg tcgtggacgg cacgacgttc gtgccgaagg
    19321 agatgaagaa ggaccaggac tgccagtcgc aggcgttcgg cgacgtgaag gcgtggctga
    19381 tcgcgaacga ctgcggcgtg ctgctgcgcg ccacctacga gacgtcggtg cagggcaagg
    19441 cggcgaccgt gctggtggcg gacatggacc tgtacgacgc gcccagcgcg aagtcgttgc
    19501 acgcggtcgt cgtgctgccg ggatccggtg gcgtgcacgg actggacggc aagccgctgg
    19561 agaacgcggc tttcgcgaac ggcaccaagg gcagccacgt gacgctggcg ttcgcggtgt
    19621 ggtcgggtgg cgcgggcgat cggacgctcg acccgatcgc caagcaggcg ttgcggcttc
    19681 ctgccacccg gtagaggctg gagggcatgg tcggacaact tcgttctgtc gtgctcgact
    19741 gcccgaatcc cgcggagctc gcgtcgttct acgaagacct gctcggcgcc gaacgtcttc
    19801 cctacggcga cgacacgtgg gtcgtgatcg tcgccaacgg cacacggctc gcgttccagc
    19861 tcgcccccga gtacgtggcg ccggtgttcc ctgatccgca cgcgtctcag caggtccatc
    19921 tcgacgtcgt ggtcgacgac gtcgagaagg cggagccgaa ggtgctggca ctcggcgcgc
    19981 ggctgctgca gaaggacacc ggcggctggt tccgggtcta cgcggacccg gtcgggcacc
    20041 ctttctgcct cgtgtggctt tcctgatccg ggcaggccct gcgccgcggg tctcgttcga
    20101 cgaaagtcgc ggctgaggtg gttcctggtg gtgcgggcgg ctgacctgca caccggtgtt
    20161 gtgttcgggt cggccgcccg tgccgtcagg ggccgcctca gccccggctt tcgcgaacac
    20221 ggacctgcgg cgcagggcct aatgtggcgc catggacttc gacgtcatcg tcatcggtgg
    20281 tggccccgta ggtgagaacg tggcttggcg gacggccgcg gggggcctgt ccaccgccat
    20341 gatcgagaag gagctcgtcg gcggcgagtg ttcgtactgg gcgtgcatgc cttcgaaggc
    20401 gctgctgcgt tcggggcacg cgctcgccgc cgcgaagcgg gtcaagggtg tggtcggcgg
    20461 gtcgctcgac gcggccgcgg tgctggagcg gcgcaccggc ttcacctcca actgggacga
    20521 caccggccag gtcaagtggg ccgagtcgga gaacatccac gtcatccgcg gcgacggtga
    20581 ggtcaccggc gaacgcgagg tcaccgtcgg tggtgaggtg taccgcgctc gccaggccgt
    20641 ggtggtgtgc accggcagcg tgccgaagat gccgccgctg gagggcctcg ccgacactcc
    20701 tgtgtggact tcgcgcgagg ccacgtcggc ccgtgaagtg cccgagtcgc tggtcgtgct
    20761 cggcggcggg gtcgtcggtg tcgagatggc gcaggcgtgg gcgcggctcg gctcgaaggt
    20821 gaagctggtg gtgtccggtg accggccgct gccgaggctg gaggatttcg tcggcccgct
    20881 ggtcgtggag ggcctgcggg aggacggcgt cgaggtgctg ctcaacgggc gtgcctcgtc
    20941 gatcaagccg ggcgagctga cgttgcagga cggccgggtc gtgcaggggt cgcacatcct
    21001 cgtcgcgacc gggcgggtac cggcgaccaa agacggcaag ccgctgacca tcgacgactc
    21061 cggtctggtg tccggtgtgg acggccgctg gctgtacgcg gccggtgacg tgaccggccg
    21121 ggcgttgctg acgcaccagg gcaagtacca ggggcgggcg gtcggcacgg cgatcctgga
    21181 gcggtcccgc gggttcgagc cgaagcagtg gtcggctggc caggcgtggg ctgatcacgt
    21241 ggcggtgccg caggtcgtgt tcaccgaccc ggaggtggcg ttcgtcgggc acaccgccga
    21301 ggaggcgcgg gctcagggcc gtgacatcaa ggtggtcgac ctggacatcg cggtcgccgg
    21361 gtcgtcgctg cacgccgacg ggtacaaggg caaggctcgg atggtggtgg acgagcgcac
    21421 gcggacgctc gtcggtgtca cgttcgtcgg tcaggacgtc gccgagctgc tgcactcggc
    21481 caccgtcgcg atcgtcgggg aggtcaccgt ggaccggttg tggcacgcgg tgccctcgta
    21541 cccgacgatc agcgaggtgt ggctgcggtt gctggagtcc tacgggctct gaatcgggtc
    21601 ctggggctct tcgagcacgg acccgagcat gccggtgagc agttcgttcg ccgtgccgat
    21661 cacgtacgcg cggtcgtcct cgtcgactcg ttcggcgagc ttgaacagcg cgtccgcggt
    21721 ctgcacggcg atccggaacg tcagcatcac cggggcgtcg ccgtgggcgc cgaaccggtt
    21781 gacgaacatc tccgccagcc gttcggccat cagctcgtac tggtcgacgc tggagtcgag
    21841 ccggtggctg tccagcatgt cgctgaaccg cacccggccg aagcccggca cgtccgtcag
    21901 catccgcatg tacaccgcga cgatctgcgt catggccccg cgccacgtgt ccgcgatcag
    21961 atccgcggcg aacagctcct cgatctcgcg gagataggtc tccataccgc gaagtgccag
    22021 agcgtgcaca acggatcgtt tgtcgggaaa gtactgatag aaggaaccaa tgggcactcc
    22081 ggccacatcg acgatgcgag ccgtggtgat gtcgtcgtag tcgtattcgt tcagcaggct
    22141 cgcacaagcg tccaggatcg cggagacagt cgccgcgccg cgctgttgca caggctgccg
    22201 gcgcatcacc ctggctaacc tgccttttgc cggatcttca tgcacacgaa catctttatc
    22261 cataagagtg cttattgccc agcacaggtt gccgacaggt tcagcccgga tctccgcgcc
    22321 gtttgcgatg aacgacccaa ccgaagtcca cgaggcagac gacggcgagt agtaaaagca
    22381 ggattccaag ccagacgagg tcagctcgca gcgccagcca gcccgccacc gagttgaaga
    22441 ccaggccgaa cccggccagc cacaaccgca aggtcagcgc gctgcgcggg ggcgcagggg
    22501 gtggcaggta gtcgctcacc tcacccggtt tcccgcagca acggtgcctc aacccgcctc
    22561 ag
//
