LOCUS       NZ_FOYL01000007        23606 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea waywayandensis strain DSM 44232, whole genome shotgun
            sequence.
ACCESSION   NZ_FOYL01000007
VERSION     NZ_FOYL01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea waywayandensis
  ORGANISM  Lentzea waywayandensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900115955.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:54:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,449
            CDSs (total)                      :: 9,363
            Genes (coding)                    :: 9,244
            CDSs (with protein)               :: 9,244
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 26 of 119
            Pseudo Genes (incomplete)         :: 101 of 119
            Pseudo Genes (internal stop)      :: 5 of 119
            Pseudo Genes (multiple problems)  :: 12 of 119
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:39:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 173724
            Orig. end                         :: 197330
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOYL01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23606
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23606
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23606
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13606](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13606
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(213..1199)
                     /locus_tag="BM417_RS26270"
                     /old_locus_tag="SAMN04488564_107154"
     CDS             complement(213..1199)
                     /EC_number="3.5.99.7"
                     /GO_function="GO:0008660 -
                     1-aminocyclopropane-1-carboxylate deaminase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009310 - amine catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420554.1"
                     /locus_tag="BM417_RS26270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107154"
                     /product="1-aminocyclopropane-1-carboxylate deaminase"
                     /protein_id="WP_093599802.1"
                     /sec_met_domain="PALP (E-value: 4e-47, bitscore: 155.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRFPLLFGPSPVHRLDRLTAHLGGAAVWAKREDCNSGLAYGGNK
                     TRKLEYLVADALATGCDTLVSIGGIQSNHTRQVAAAAARAGLKAVLVQESWVDWADVGS
                     DRVGNILLSRMMGADVRLVSAEFGIGVKPAWEQAIEEVRANGGKPYPIPAGASDHPLGG
                     MGFANWADEVRQQEAQLGVFFDTVVVCSVTGSTQAGMVAGFANDTGRRVLGIDASAKPA
                     ETLAQITRIAHNTAKLCEVTVSEEDILLDDRFHAGIYGIADESTVDAMRLGASLEGMIT
                     DPVYEGKSLAGLIHLVSSGEIGRDSTVLYAHLGGQPALNAYSSLFPA"
     gene            complement(1196..1825)
                     /locus_tag="BM417_RS26275"
                     /old_locus_tag="SAMN04488564_107155"
     CDS             complement(1196..1825)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099104.1"
                     /locus_tag="BM417_RS26275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107155"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_093599805.1"
                     /transl_table=11
                     /translation="MQYIGYGSLKERAAAEIRSAIVRGDLEPGTPIKDVELAEKLGLSR
                     TPVREALATLTDEGLVETKPHAYTRVTALEAEPVRDALVVVQSMHALAIGIAVPKMPAE
                     DIAAMRAANKAFKKALDANDAVAALAADDDFHAVAVHRCDNFAIAATIDRFTPLVRRAE
                     HSRFSSPDARHSVTQHQQIIEACEKGDTALAATLVDENWSTLEDEL"
     misc_feature    complement(1816..1831)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.62"
                     /tool="antismash"
     gene            complement(1916..2479)
                     /locus_tag="BM417_RS26280"
                     /old_locus_tag="SAMN04488564_107156"
     CDS             complement(1916..2479)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099095.1"
                     /locus_tag="BM417_RS26280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107156"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_093599808.1"
                     /transl_table=11
                     /translation="MTASPRLERIVEMTASELNVRLGEALALYVTAMNYPPGTVEQRAP
                     MWLAHMMREDWRCVVALGEQDELVGIGYGYRGAAGQWWHEQVRRGLMQVSPPTVVEDWL
                     TDYFELTELHVLPRAQGRGLGEDLLHRLMEGVSSSRVLLSTPEGPSKAWKLYRRVGFVD
                     VLRHYQFTGDPRPFAVLGRALPVS"
     gene            complement(2476..2964)
                     /locus_tag="BM417_RS26285"
                     /old_locus_tag="SAMN04488564_107157"
     CDS             complement(2476..2964)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419640.1"
                     /locus_tag="BM417_RS26285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107157"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_093599811.1"
                     /transl_table=11
                     /translation="MSALEHPGIRKVAEALPPATAERIVVLPDAVRTAAAAAEAVGVQV
                     GAIANSLLFAAVRDGVAAPLLVLTSGAHRADTSMVAELVGADAVKRADPEFVREHTGQV
                     IGGVSPVGHPAPIETIVDRALSGHEEIWAAAGHPHAVYPTTFADLVALTGGRVAVVTA"
     misc_feature    complement(3046..3061)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.24"
                     /tool="antismash"
     misc_feature    3047..3060
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.98"
                     /tool="antismash"
     gene            3168..3587
                     /locus_tag="BM417_RS26290"
                     /old_locus_tag="SAMN04488564_107158"
     CDS             3168..3587
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686257.1"
                     /locus_tag="BM417_RS26290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107158"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_093599814.1"
                     /transl_table=11
                     /translation="MTADLSNPAAFPIPLPPASALALLRQAHDSLAESERTPEPPERFA
                     TAYLAALRAAAAVLALRGRPHRGRSRPTSAWVLLGALAPEMSEWAAFFASWSSTRAAVL
                     AGITRHVDARTADDLVRQTHQFVLLVDRVMSEATR"
     misc_feature    3348..3350
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3584..4330
                     /locus_tag="BM417_RS26295"
                     /old_locus_tag="SAMN04488564_107159"
     CDS             3584..4330
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099098.1"
                     /locus_tag="BM417_RS26295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107159"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_245822179.1"
                     /transl_table=11
                     /translation="MNSLDILRREAELLAMSAIGQPPHKGVPACPGLNLGETVRHVGGG
                     YRGVLAWIRLGREPRAGEWQDYPAAGEDTLDFMRSGAEAVIAELEAHDEDEPCATWWPD
                     RQNYGFWRRRLAHETTVHRMDVQGASGVEPGAVADEVAIDGVDEVLTLWLGHKLDVLGV
                     RGSRESLVTIQVEDHLWLTRCGPHGASAWRVVDPEDTHVADAQVSASPMTMYRWLWGRL
                     PDRMVEAIGDHDAIAQLWALLRLATK"
     gene            complement(4307..5875)
                     /locus_tag="BM417_RS26300"
                     /old_locus_tag="SAMN04488564_107160"
     CDS             complement(4307..5875)
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0004035 - alkaline phosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099099.1"
                     /locus_tag="BM417_RS26300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107160"
                     /product="alkaline phosphatase D family protein"
                     /protein_id="WP_093599817.1"
                     /transl_table=11
                     /translation="MAKLVLGPLLRHVDESSATVWVETDASCEVVIAGHIARTFQAGRQ
                     HFALVRLENLGPRTEYDVRLDGETVWPEPGSGFPTPVIRTGEVRRIAFGSCRAAPTQPV
                     GPDALDAFAQRLMETSEDEWPQALVLLGDQVYADEPTEATKQWLRDRRQGTEEPDGEVV
                     HFGEYARLYHETWGDPEIRWLLSVVPTAMIFDDHDVRDDWNTSAVWRAEMADKPWWRDR
                     IRGALSSYWVYQHLGNLGPNELARDPLYAKVKAQDTDVLPLLEEFAEEADREVEGRKST
                     WWSFRRDFGRVRLLMVDTRSGRILDEGKRQMVSDAEFEWIERNTDGDDIDHLLIGSSLP
                     WLMPHALSHFQSLNEIGARKPGWQGKAAEGIRQAVDLEHWPAFRESFDRLSRMIEKAAG
                     NGAATVCVLSGDVHHSYVAEAEFARPTKAVVAQLVCSPIHNEAPKFLRPGFRLSWSRAA
                     SWVFRRLATLAGVPEDLVHWRKTSGPHFGNSVALLDFDGRRARYRLLSATGEETASVLL
                     GREPQ"
     gene            5900..6394
                     /locus_tag="BM417_RS26305"
                     /old_locus_tag="SAMN04488564_107161"
     CDS             5900..6394
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037170.5"
                     /locus_tag="BM417_RS26305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107161"
                     /product="VOC family protein"
                     /protein_id="WP_093599820.1"
                     /transl_table=11
                     /translation="MEITFEAADPPALAAFWSEFAGDELELTFVWSDAPKIEKNRVHID
                     LASSSPEHQADIVARALKLGAELADVGQTDVPWVVLRDPQGNEFCVLEPRHEYPGVIAA
                     VVVDSRDPLASAQATGHPVVRSGDGFASVRPEPGPWLEFVRTDDAEPITNRVRVRWADP
                     A"
     misc_feature    5901..5915
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    5901..5916
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            complement(6641..8293)
                     /locus_tag="BM417_RS26310"
                     /old_locus_tag="SAMN04488564_107162"
     CDS             complement(6641..8293)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099093.1"
                     /locus_tag="BM417_RS26310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107162"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_093599823.1"
                     /transl_table=11
                     /translation="MASVHEISNKFVSDYVALDPITATSLGFAGADDQLTDLSPEGHAA
                     RDELAVRALAAITAAQPADASEEAARAVFLERTGLEHELYEAGETESSLNVIASPIQSV
                     RDIFDQMPTDTPEQWATIGRRLSAVPAALDGLRASLSHAASRGHVSAIRQVTQVAKQCD
                     TFATTFFGPFAASADVDGSVRSSLDAGATAAAAAYADFASFLRTTLAPQAPQKDAVGEE
                     RYRLGSRYFTGSRLDLAEAYAWGWEEFLGIEAEMKKVAARLKPGASLAETAAFLDEHPR
                     YQVHGQDGLQTWMQELSDKALLDLRDVHFDLPDALMSLECKIAPPGGAVGAYYTPPTAD
                     FSRPGRMWWSIAEGKSVFPTWRETSTVYHEGVPGHHLQCATAVYQSETLNDFQRLMCWV
                     SGHGEGWALYAERLMRELGYLDDDGDLLGMLDAHLFRAARVIIDIGMHLELEIPAGTGF
                     HPGERWTPELGLEFMMTRTLSEPAHIRDEIDRYLGWPGQAPAYKIGERLWLAAREDART
                     RKGADFDLKRFHKEALEMGAMGLDTLRERLAAL"
     gene            8401..9054
                     /locus_tag="BM417_RS26315"
                     /old_locus_tag="SAMN04488564_107163"
     CDS             8401..9054
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099092.1"
                     /locus_tag="BM417_RS26315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107163"
                     /product="DUF3153 domain-containing protein"
                     /protein_id="WP_093599826.1"
                     /transl_table=11
                     /translation="MRRSRALLLPVFLLLTLFSLSGCVRVYAAMAVSDDDRISGEIVAA
                     TPPTQDNDPGPQLKVPPELASRVTTKPYRVESYAGTQLFFNGLSFDEMRTLSTSTSSSN
                     SRYSLSFRRSGDLVTLSGSVDLTQVPVERADIQVKVSFPGKIVNTNGREEENNTIAWSP
                     KPGQASMLQATVQYAGENSSSFFGWALLVAGLTGGAALIVVVLALIAHKRNVTL"
     gene            complement(9051..9932)
                     /gene="metF"
                     /locus_tag="BM417_RS26320"
                     /old_locus_tag="SAMN04488564_107164"
     CDS             complement(9051..9932)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332694.1"
                     /locus_tag="BM417_RS26320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107164"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_093599829.1"
                     /transl_table=11
                     /translation="MTSVVERLRGESPKFSVEFLPPRDAEDEKILWKAVRELEGLDPAF
                     VSITYGAGGSRRDRTIRATGRIAQETTLLPVAHLTAVEHSVAELRNVIGWYAAIGVRNI
                     LALRGDPPGDPMGEWVAHPEGLNYADELVRLVRELGDFCVGVAAFPYGHPRSGDLDTDL
                     KFLLRKLDAGADYAVAQLFHAPEPFLRMRDRVADAGCSAAILPGIMPMLSPRGLAKIVE
                     LSGADLPLDVSRRLEPYADDVAGFRATGIDIATEMCQRLLDEGVPALHFYTMNRSKATK
                     EVLGRLGLVTRA"
     gene            10001..11104
                     /locus_tag="BM417_RS26325"
                     /old_locus_tag="SAMN04488564_107165"
     CDS             10001..11104
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099089.1"
                     /locus_tag="BM417_RS26325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107165"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_093600685.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-46, bitscore:
                     153.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVPDTADHGRVSHHPIDVALPQHVEAALTTYLASRRASGEAMD
                     PSFASAVDALSDFVLGGGKRIRPTYAWWGWRAAGGDPDGELADEVLTAVSSLELIQACA
                     LIHDDLMDASSVRRGKPTVHIAFGARHREQGWLGSSERFGMSAAVLIGDVALAWADDML
                     FAAGLPSEVLRRMSEPWRDMRTEMLAGQYLDVLTQARGDSSADAALRIDRLKTAAYTVE
                     RPLHMGAAMAGGSPELIDGLRAFGADIGVAFQLRDDLLGVFGDPEVTGKPAGDDLAEGK
                     RTLLVALGMQFGADILDIALGKPDLDLDTVEEVRRTLVKVGAVDAVEERIEELTKSALA
                     ALDAAPVAEPAAAKLAGLAISSTKRAF"
     gene            11274..12722
                     /gene="mptB"
                     /locus_tag="BM417_RS26330"
                     /old_locus_tag="SAMN04488564_107166"
     CDS             11274..12722
                     /codon_start=1
                     /gene="mptB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800240.1"
                     /locus_tag="BM417_RS26330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107166"
                     /product="polyprenol phosphomannose-dependent alpha 1,6
                     mannosyltransferase MptB"
                     /protein_id="WP_245822181.1"
                     /transl_table=11
                     /translation="MRTNTYAIPIRTTMLGLLGVALIALGGMGAGAILERDPLLAQVGL
                     SWLRYGHGRDLASMVLYLGLGLVIWAWIRLGRLVRWGEIGDFAVLVAVTVWTLPLLFAP
                     PLFSKDIYSYLAQGQLALSGYDPYTVGPAVLQSTLSENVSWVWQHTPAPYGPLFILVAK
                     AIVWITDASVILGVVAMRLSLAGGLVLLCWALPGLSRHLGGKSAIALWLVAANPLVLVH
                     LIGGAHNDLLMIGLMAAGVLLVLDRRHVLGFVLLSLAFSVKATAVVIVPFLVWIWAARL
                     EGDKRAQFRKALLPGLATFLGTFLVCTLIAGVSLGWIPALRSSSMIINWLSLPSAVGDF
                     VRMVVNWFVYVDGGIFIGVARALGSVVLIWIAYTQWWASRDGEVRDAVRRGALTLLAVA
                     LLSPATLPWYFTWALALAAGFAWSTGALVTVTTASLFLLLVTFPNGDTALYSWGYLAFA
                     LVVSALAARSLVKPDPFGLSSRYE"
     gene            12719..13606
                     /locus_tag="BM417_RS26335"
                     /old_locus_tag="SAMN04488564_107167"
     CDS             12719..13606
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686266.1"
                     /locus_tag="BM417_RS26335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107167"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_093599832.1"
                     /sec_met_domain="phytoene_synt (E-value: 5e-102, bitscore:
                     335.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.9e-60,
                     bitscore: 197.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPGTVDLGSAYAACRRVNARYGKTFFLATTLLRPDQRPAVHALY
                     AFARWADEIVDAAGVTDRAGELDRVERLLEKAPSNPILHALADTMHRYDIDRSLFTDFL
                     ASMRMDLDVTEYADLDALGVYVHGSAEVIGLQMLPVLGTVVPREEAEPYAARLGAAFQL
                     TNFLRDVGEDLDRGRVYLPQDVLGAHGVDRDLLQWCRRHRRANDRVQRALDDLVAHSYA
                     IYQSAEPGIGMLSATSRPCMQTAYTLYRDILGLVGCEVLWRRVAVPNSRRLAVAAPGVG
                     RALLARVTTHGIPG"
     gene            complement(13687..14052)
                     /locus_tag="BM417_RS26340"
                     /old_locus_tag="SAMN04488564_107168"
     CDS             complement(13687..14052)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="BM417_RS26340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107168"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_030474641.1"
                     /transl_table=11
                     /translation="MSAIPAAADVLAADLEVLPLPEVADRMGLPVTRVHQMLRDGQLLA
                     ERRAGVLVVPEAFLAAGGVVKGLPGTITVLRDQNYSTDEILRWLFTEDESLPGTPIEAL
                     RGDRGREVKRRAQAMGF"
     gene            14130..16151
                     /gene="pknB"
                     /locus_tag="BM417_RS26345"
                     /old_locus_tag="SAMN04488564_107169"
     CDS             14130..16151
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637672.1"
                     /locus_tag="BM417_RS26345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107169"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_093599835.1"
                     /sec_met_domain="Pkinase (E-value: 8.6e-49, bitscore:
                     161.1, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERSVSNVMGGLLEQRYRVDSVLARGGMSTVYRGRDTRLDRDVAI
                     KVMDPHLTADPAFVARFEREARAAAQLHHPAVVSVHDQGVDGDQVYLVMELIDGGNLRD
                     LLNQRGKLAPAVALSILGPVLSALGAAHRAGLVHRDVKPENVLIGPGGQVKVADFGLAR
                     AIAENGVTSDSEILGTVAYLSPEQVESGAADARSDVYAAGIVLYEMLAGQAPYRGETAI
                     SVAYQHVNSDVPSVPEIPLALDTLVRKATRRDPVLRPANADAFLAELERVGTDLGLTPQ
                     PVPVPGSAPENDRTVIMRPVPVAVGATPPSAAELTRPVVPKPSLNSAAMTTVSTGPPPP
                     PPGISGTRTMQRPEPPRRRPPQKKKPKVDPVEEERKRRKKLFTIWGSVVVVVAIIVGLF
                     SWYVGAGRYTEMPSVAGQSEQNAMVLLSKADLTGLVEKVPSNDVPNGTVISSDPGPGAE
                     LRKNQQVKLVVSRGRPVVPFINTGVDEAAATKDIEAAGLKAVKDATKDAFHDTVPIGKV
                     VGVDPRPGTALALDAPVTLILSKGPPPRLPVPNVTGKTKDEAVAELQRAGLEAVDAGGE
                     DAPENNGSRVVRTDPPAGTVLDPTQNKRVTLFYQNNQEIEVPDVTRQKVREAKEQLEQA
                     GLRVKVEFNKSNNATVVNQSIPPRTRVKRGTEITIVGL"
     gene            complement(16237..17625)
                     /locus_tag="BM417_RS26350"
                     /old_locus_tag="SAMN04488564_107170"
     CDS             complement(16237..17625)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800237.1"
                     /locus_tag="BM417_RS26350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107170"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_093600691.1"
                     /transl_table=11
                     /translation="MNWTVDVPIDTLPELPPLPPEMRKRLDDALSRPAAQQPDWPDAEQ
                     VRRVRTVLESVPPITVPAEIDRLHTQLAQVANGEAFLLQGGDCAETFADNTEPHIRANI
                     RTLLQMAVVLTYGASLPVVKVGRIAGQYAKPRSSGIDALGLPSYRGDIINSLVATPEAR
                     VADPGRMIRAYANAGAAMNLLRALTGAGLADLHRVHDWNRDFVRTSPAGERYEALAGEI
                     DRGLKFMSACGVNDQSLHGTEIFASHEALLLDYERALLRLDTTRDEPRLYDLSSHFVWI
                     GERTRQLDGAHIAFAEMLSNPIGLKIGPTTTPEMAVEYVERLDPRNEPGRLTLISRMGN
                     QKVRDVLPAIVEKVEASGHKVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGFFEVHR
                     RLGTHPGGIHIELTGEDVTECLGGAQEISDDDLAGRYETACDPRLNTQQSLELAFLVAE
                     MLRS"
     gene            17801..18808
                     /locus_tag="BM417_RS26355"
                     /old_locus_tag="SAMN04488564_107171"
     CDS             17801..18808
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022646.5"
                     /locus_tag="BM417_RS26355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107171"
                     /product="DUF2891 domain-containing protein"
                     /protein_id="WP_177320612.1"
                     /transl_table=11
                     /translation="MDATRLDDSTATRLLGIAIDNIQRDHPVHWTHVIDGDHGLVPQRV
                     LHPVFAGSFDWHSCVHQTWLAVRLLRLRPSLAGADTARNALDKLITPENCAVEASFFAS
                     RAGRHWERPYGWAWLLLLDAELRTSGLPWSVAPIADVLRDRWLEWISAARLPIRTGTHS
                     NTAFATGLVYDTAQVNGDSELASACVDAALRWHRDEAGYGGFEPDAADFLSPALTTADL
                     MRRALSTAEFADWFDAYLPDLESERWRVLREPYPVDDPSDPYGSHLAGLALSRAWNWEA
                     IAGALPDGHRYTSLARTASAAHREAGWTYVFGGHGYMADHWLGSFGAYLDAKAF"
     gene            complement(18904..19668)
                     /locus_tag="BM417_RS26360"
                     /old_locus_tag="SAMN04488564_107172"
     CDS             complement(18904..19668)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013676255.1"
                     /locus_tag="BM417_RS26360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107172"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_093599841.1"
                     /transl_table=11
                     /translation="MTEVPNTLLGKVMSVLNAFGADDDELGFAELGRRTGLSKATLHRL
                     LGDLAEVRLLDRGTRGYRLGGHLFQLGIRASVERRLVEVSTPYLEDLYERTHETVHLGL
                     LEGHEVVYAAKIGGHRQASSPSRLGGRMPLHATAIGKALLAHSQPSLRTEVLSAPLARR
                     TPRTVVTPGMLRRQLATIRQTGVAYEFEESRVGLACVASPVLGHDGAVVAAVSVAGPTT
                     RFDPRVHAASVHAAATGIALTLIRRATLSSGT"
     gene            19749..20528
                     /locus_tag="BM417_RS26365"
                     /old_locus_tag="SAMN04488564_107173"
     CDS             19749..20528
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005464750.1"
                     /locus_tag="BM417_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107173"
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="WP_093599844.1"
                     /transl_table=11
                     /translation="MNEVLIAAERLATAAREKVPCAPVRDLIGDAEAYAVQQHNIAARI
                     ADGATVVGRKIGLTSPAVQQQLGVDQPDFGVLLDDMAYKDGDELPVSGLLQPKIEAELA
                     FVLKADLAEGPFDEQTVANAVGHVKASLEIVDSRISGWDITFADTVADNASSGLFVLGT
                     EQADLGEVVPKNVSMVLSVNGEERSAGSGAACLGDPLTALAWLATTAADLGAPLKAGDV
                     VLSGALGPMVGVQAGDQVEATITGLGTVRATFAKQEA"
     gene            20528..21451
                     /locus_tag="BM417_RS26370"
                     /old_locus_tag="SAMN04488564_107174"
     CDS             20528..21451
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013676256.1"
                     /locus_tag="BM417_RS26370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107174"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_093600694.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.2e-09, bitscore:
                     32.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTKVAIIGSGNIGTDLVIKVLKRSTTLQVAALVGIDPESDGLAK
                     ARKLGVPTTSDGIQGLVAMPGFEEIEIVFDATSAGAHAKHAEILAAHGKRVIDLTPAAI
                     GPMVVPTVNLDEHLSAPNVNMVTCGGQATIPIVAAINTVTPVPYAEIVASISSRSAGPG
                     TRANIDEFTETTAQAIADVGGAHRGKAVIVLNPADPPITMRDTVLALVNAPDPQTQHRI
                     RASVEYMITQVAAYVPGYRLKQPVQIDPVDQPHTLTEEPVTHQVTVLLEVEGAADYLPA
                     YAGNLDIMTSAALRVAETMAKAVVRA"
     gene            21448..22452
                     /gene="dmpG"
                     /locus_tag="BM417_RS26375"
                     /old_locus_tag="SAMN04488564_107175"
     CDS             21448..22452
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011489333.1"
                     /locus_tag="BM417_RS26375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107175"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_093599847.1"
                     /sec_met_domain="HMGL-like (E-value: 7.4e-65, bitscore:
                     214.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYLQDVTLRDGMHALRHRIDPQKVTEIARALDQAGVDAVEVSH
                     GDGLSGGSLVYGPGSHTDWEWIEAAAEALTQAKLTTLLLPGIGTLHDLKRAHSLGVRSV
                     RIATHCTEADISAQHIAGARDLGMDVSGFLMMSHLAEPQELARQAKLMESYGANCVYVT
                     DSGGRLLPHDVRTRIRAYKDVLDADTEIGIHAHENLSLAVANSITAVEEGATRVDASLA
                     GLGAGAGNCPIEPFVAVANLQEWQHNADLFALQDAADDLVRPLMDRPVRVDRESLTLGY
                     AGVYGSFLRHADTAAQRTGADVRTLLLEAGRRRLVGGQEDMLTDIALDLTRQT"
     gene            complement(22436..23368)
                     /locus_tag="BM417_RS26380"
                     /old_locus_tag="SAMN04488564_107176"
     CDS             complement(22436..23368)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227515.1"
                     /locus_tag="BM417_RS26380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_107176"
                     /product="2,3-dihydroxyphenylpropionate 1,2-dioxygenase"
                     /protein_id="WP_093599850.1"
                     /transl_table=11
                     /translation="MAEIIGFAGMSHSPFATLLPPDGSDGPGSVFLRDADRVRLAVEKL
                     APDAIVVIGPDHFHANFYDVMPPFVLGVEEAVGFGDFGSSSGPLPVAQTLAWSAHSGLA
                     DAGFDVSLSYSLTVDHGIVQSYEMITGGTTLPLVPLVVNTAAPPLPSLDRCVELGRALG
                     AALRSSVFPGRVLVVASGGLSHWLPSNDPRDPSVVGERRESLIRGRAYAKEFAAAREPR
                     VKAMGGNPEAKVNAVWDGWFLDRLSAGSAGEIASLGHEALEDHAGSGGHEIRCWLIGQV
                     AVGLPLVWTSYEPVPEWITGMGIGTTFAV"
     misc_feature    complement(23102..23104)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 aggaggtaag tcactgctgt cgttcaccga cgacgagccg accctgcgca ccgccgcgaa
       61 cgccctgagc cgggcggtcc gcgacggctg gctgggccag ctggcggtcc agcgagccga
      121 cggcgaggtc gcgctcacct cgcacctggc gacggtgctt caggaagccg gtttccgcgc
      181 cacaccgaag ggtctgcgcc tgcgcgcgtg atttacgcgg ggaacaggga gctgtaggcg
      241 ttgagagccg gctgtccgcc gaggtgggcg tagaggaccg tgctgtcgcg gccgatctcg
      301 cccgacgaca cgaggtggat gagccccgcc agggactttc cctcgtagac cgggtcggtg
      361 atcatgcctt cgaggctcgc acccaggcgc atggcgtcca cggtggactc gtcggcgatg
      421 ccgtagatgc cggcgtggaa gcggtcgtcg aggaggatgt cctcttcgga caccgtgacc
      481 tcgcacagct tggcggtgtt gtgcgcgatg cgggtgatct gggcgagagt ctcggccggc
      541 ttggcggagg cgtcgatgcc cagcacgcgg cggccggtgt cgttcgcgaa accggcgacc
      601 atgcccgcct gggtgctacc ggtgaccgag cagacgacga cggtgtcgaa gaagacgccg
      661 agctgggcct cctgctgtcg gacctcgtcg gcccagttcg cgaagcccat gccgcccagc
      721 gggtggtcgg aggcgccggc ggggatcggg tagggcttgc cgccgttcgc gcggacctct
      781 tcgatcgcct gttcccaggc gggtttgacg ccgatgccga actcggcgct caccagccgg
      841 acgtcggctc ccatcatgcg gctgagcagg atgttgccca cccggtcgct gccgacgtcg
      901 gcccagtcga cccagctctc ctgcaccagc acggctttca gaccggcccg cgccgcggcg
      961 gccgcgacct ggcgggtgtg gttggactgg atgccgccga tcgacacgag ggtgtcgcag
     1021 ccggtggcca gggcgtcggc gacgaggtac tcgagcttgc gggtcttgtt gccgccgtag
     1081 gcgaggccgg agttgcagtc ctcgcgcttg gcccagaccg cggcgccacc gaggtgggcg
     1141 gtgagacggt ccaggcggtg cacgggcgag ggaccgaaga ggagcgggaa tctgttcaca
     1201 gttcgtcctc cagggtgctc cagttctcgt cgaccagggt ggcggccagc gcggtgtcgc
     1261 ccttctcgca cgcctcgatg atctgctggt gctgcgtgac ggagtggcgg gcgtccggtg
     1321 aggagaaccg gctgtgctcg gcccggcgca ccagcggggt gaagcggtcg atggtcgcgg
     1381 cgatcgcgaa gttgtcgcag cggtgcacgg ccaccgcgtg gaagtcgtcg tcggcggcca
     1441 gcgcggcgac ggcgtcgttc gcgtcgagcg ccttcttgaa ggccttgttc gcggcccgca
     1501 tggcggcgat gtcctcagcc ggcatcttcg gcaccgcgat gccgatggcg agggcgtgca
     1561 tggactggac gacgacgaga gcgtcccgca cgggttccgc ttccagcgcg gtgacacggg
     1621 tgtacgcgtg cggcttggtc tcgaccaggc cctcgtcggt cagcgtggcg agcgcctcgc
     1681 gcaccggggt gcgggacagg ccgagcttct ccgccagttc gacgtccttg atgggcgtgc
     1741 ccggctccag gtcgccgcgc acgatcgccg accggatctc ggccgccgcc cgttccttca
     1801 gtgacccata tccaatatat tgcatatcag tgagcgtagg acgcgggccg ggtgatcgca
     1861 acaacaagcc cccgagccgc agtgcgactc gggggcttgg atggttccag gcgagttagc
     1921 tgacaggcag ggcgcggccg aggaccgcga acggccgtgg gtcgcccgtg aactggtagt
     1981 gccgcaacac gtccacgaag ccgacgcggc ggtagagctt ccacgccttg ctcgggcctt
     2041 cgggcgtgga cagcagcacg cgggaggacg acacgccctc catcaggcga tgcaacaggt
     2101 cctcgccgag gccacggccc tgggcgcgcg gcagcacgtg cagttcggtc agctcgaagt
     2161 agtcggtgag ccagtcctcg acgacggtgg gcggcgagac ctgcatcagc ccgcgccgca
     2221 cctgctcgtg ccaccactgg ccggccgcgc cgcggtagcc gtagccgatg ccgacgagct
     2281 cgtcctgctc tcccagcgcg acgacgcagc gccagtcctc gcgcatcatg tgcgcgagcc
     2341 acatcggggc gcgctgctcg acggtgcccg gcgggtagtt catcgccgtc acgtacagcg
     2401 cgagcgcttc gcccagccgc acgttcagct ccgaggcggt catctcgacg atgcgctcca
     2461 ggcgcggcga ggccgtcatg ccgtcaccac cgccacgcgt ccgcccgtca gcgccaccag
     2521 atccgcgaag gtcgtggggt agacggcgtg cggatgaccc gcggccgccc agatctcctc
     2581 gtggccggac aacgccctgt ccacgatggt ctcgatcggc gccgggtgcc cgaccggcga
     2641 caccccgccg atcacctggc ccgtgtgctc gcggacgaac tcggggtcgg cgcgcttcac
     2701 cgcgtccgcg cccaccagtt cggccaccat cgacgtgtcc gcgcggtgcg cacccgaggt
     2761 caggaccagc agcggggccg cgaccccgtc gcgcaccgcg gcgaacagca ggctgttcgc
     2821 gatcgcgccg acctgcacgc ccaccgcttc cgcggcggcc gccgcggtcc gcacggcgtc
     2881 cggcagcacg acgatgcgtt cggcggtggc gggcggcagg gcttccgcga ccttgcggat
     2941 tccggggtgt tcgagcgcac tcacgtctcc atcagaccac gactcgcgcc cacgtggtgg
     3001 ggcgggttga ggaatccatc ggccgggagc tacgctgatg aggactcgaa catgtgttcg
     3061 agtcgaacca tgcctcggag gtggggtggg ggaagcaccc cacctccgag agccgccggc
     3121 ttcccctcgg cggtgacgtc gttcaccgac gccactagga ggccgagatg acagccgatc
     3181 tttcgaatcc ggcagccttc cccatcccgt tgccacccgc gtccgcgctc gccctgctgc
     3241 ggcaggccca cgactcgctc gccgagtcgg agcgcacgcc cgaaccccct gagcggttcg
     3301 cgaccgctta cctcgccgca ctgcgcgcag ccgccgcggt gctcgcctta cgtggacgac
     3361 cccatcgcgg gcgatcgagg ccgaccagcg cgtgggtgct gctcggcgcg ctcgcgccgg
     3421 agatgagtga gtgggcagct ttcttcgcgt cgtggtcgtc cacacgggcg gccgtgctcg
     3481 cggggatcac ccggcacgtc gacgcgcgca cggccgacga cctggtgcgc cagacccatc
     3541 agttcgtgct gctcgtcgac cgcgtgatga gcgaggcgac gcggtgaact ctctcgacat
     3601 cttgcgtcgt gaggcggaac tgctcgccat gtccgcgatc ggccagccac cgcacaaggg
     3661 cgtgccggcc tgtcccggac tgaacctcgg ggagaccgtg cggcacgtcg gcggcggtta
     3721 tcgcggcgtg ctggcgtgga tcaggctcgg ccgtgagccc agggccggcg agtggcagga
     3781 ctacccggcg gcgggcgagg acacgctcga cttcatgcgg tcgggcgcgg aggccgtgat
     3841 cgcggagctt gaagcgcacg acgaggacga gccgtgcgcg acgtggtggc ctgaccggca
     3901 gaactacggg ttctggcggc gacggctcgc gcacgagacg acggtgcacc gcatggacgt
     3961 ccagggcgcc tccggcgtgg aacccggtgc cgtcgccgac gaggtcgcga tcgacggcgt
     4021 cgacgaggtg ctcacgttgt ggctggggca caagctggac gtgctcgggg tgcgggggtc
     4081 gcgggagagc ctcgtgacca tccaggtcga ggaccacctg tggctcacgc gctgcggtcc
     4141 gcacggcgcg tcggcgtggc gcgtggtcga cccggaggac acccacgtcg ccgacgcgca
     4201 ggtgtcggcg agtccgatga cgatgtaccg ctggctgtgg ggacggttgc ccgaccggat
     4261 ggtcgaggcg atcggcgacc acgacgccat cgcgcagctg tgggcgctac tgcggctcgc
     4321 gaccaagtag gacggacgcg gtctcctcgc ccgttgccga caacagccgg tagcgggcgc
     4381 ggcggccgtc gaagtccagc agcgccacgg agttcccgaa gtgcgggccg ctggtcttgc
     4441 gccagtgcac caggtcctcc ggcacgccgg ccagtgtcgc gaggcggcgg aacacccacg
     4501 aggccgcgcg ggaccacgac agccggaacc ccggtcgcag gaacttcggc gcctcgttgt
     4561 ggatgggcga gcacacgagc tgcgcgacca ctgccttggt gggcctggcg aactcggcct
     4621 cggcgacgta gctgtggtgg acgtcgccgg acagcacgca caccgtcgcg gcgccgttgc
     4681 ccgcggcctt ctcgatcatc cgcgagagcc ggtcgaacga ctcccggaac gccggccagt
     4741 gctccaggtc gaccgcctgc ctgatccctt cggcggcctt gccctgccag cccggtttgc
     4801 gcgcgccgat ctcgttgagg gactggaagt gactgagcgc gtgcggcatc agccacggca
     4861 gcgacgagcc gatcagcagg tggtcgatgt cgtcgccgtc ggtgttccgc tcgatccact
     4921 caaactcggc gtcgctgacc atctgccgct tgccctcgtc gaggatgcgg cccgagcgcg
     4981 tgtcgaccat gagcagccgg acgcggccga agtcgcggcg gaagctccac cacgtcgact
     5041 tgcggccctc cacctccctg tccgcctcct cggcgaactc ctccagcaac ggcagcacgt
     5101 ccgtgtcctg ggccttcacc ttggcgtaca agggatcccg cgcgagctcg ttcgggccga
     5161 ggttgcccaa gtgctgatag acccagtacg aggagagggc gccgcggatc ctgtcgcgcc
     5221 accacggctt gtccgccatc tccgcgcgcc acaccgcgga cgtgttccag tcgtcgcgca
     5281 cgtcgtggtc gtcgaagatc atcgccgtcg gcacgaccga cagcagccag cggatctcgg
     5341 ggtcgcccca ggtctcgtgg tagaggcggg catactcgcc gaagtgcacg acctcgccgt
     5401 cgggctcctc cgtgccctgc ctgcgatcac gcagccactg cttggtggcc tcggtgggtt
     5461 cgtcggcgta gacctggtct cccagcagga caagcgcctg cggccactcg tcctcggacg
     5521 tctccatgag ccgttgcgcg aacgcgtcga gggcgtcggg cccgaccggc tgggtcggcg
     5581 cggcacggca cgacccgaag gcgatccggc ggacctcacc ggtgcggatg accggcgtcg
     5641 ggaacccgct gccgggttcc ggccagaccg tctcgccgtc gagcctgacg tcgtattccg
     5701 tgcgcgggcc gaggttctcg agtctgacga gcgcgaagtg ctgccggccg gcctggaacg
     5761 tgcgcgcgat gtgcccggcg atcacgacct cgcacgaggc gtcggtctcg acccacaccg
     5821 tcgcggacga ttcgtcgaca tgcctcagga gcggtccgag caccagcttc gccacgcgcg
     5881 agacagtacc ctcgtacgcg tggaaatcac gttcgaggca gcggatcccc cggccctggc
     5941 cgcgttctgg tccgagttcg ccggtgacga gctcgagctg acgttcgtgt ggagtgacgc
     6001 gccgaagatc gagaagaacc gggtgcacat cgacctggcc tcgtcgtcgc ccgaacacca
     6061 ggcggacatc gtggcgcgcg cgttgaagct cggcgccgaa ctcgccgacg tcggtcagac
     6121 cgacgtgccg tgggtggtgc tgcgcgatcc gcagggcaac gagttctgcg tcctcgaacc
     6181 ccgccacgaa tatcccggcg tgatcgccgc cgtcgtcgtc gactcgcgtg atccgctggc
     6241 gtcggcccag gcgaccgggc atccggtggt gcgcagcggg gacggcttcg cctcggtccg
     6301 gcccgagccg ggtccgtggc tcgagttcgt gcggaccgat gacgcggagc cgatcacgaa
     6361 ccgcgtgcgc gtccggtggg ccgatccggc gtaacgggtc gaaagaaggc ccgcgaggcg
     6421 ctcagcggat caaggacgcc gaaccgttcg acaacagcct cacggacacc ggcttcgacg
     6481 tctcgatgtt ccgcccgcgc cgcaccggca cccactgata tccgatatat cagccccctc
     6541 gccacaccgg cttgtgcaaa agacgtttgc ggacgtccgc aaacgtcttt tgcataaggg
     6601 tggatcggcg cagttcagaa ggttgcgcgg cgggcgtgga tcagagggcg gccaaccgtt
     6661 cacgaagggt gtcgaggccc atcgcgccca tctccagggc ctccttgtgg aagcgcttga
     6721 ggtcgaagtc ggcgcccttg cgggtgcgtg cgtcctcgcg ggcggcgagc cacaggcgct
     6781 cgccgatctt gtacgccggt gcctggcccg gccagccgag gtagcggtcg atctcgtcgc
     6841 ggatgtgggc gggttccgag agcgtcctgg tcatcatgaa ctccaggccg agctcgggcg
     6901 tccagcgctc gccggggtgg aagccggtgc cggccgggat ctccagctcc aggtgcatgc
     6961 cgatgtcgat gatcacgcgg gccgcgcgga acaggtgcgc gtcgagcatg ccgagcaggt
     7021 cgccgtcgtc gtcgaggtag ccgagttcgc gcatgaggcg ttccgcgtag agcgcccagc
     7081 cctctccgtg gcccgagacc cagcacatca ggcgctggaa gtcgttcagc gtctccgact
     7141 ggtacacggc cgtcgcgcac tggaggtgat ggcccggcac gccctcgtgg tagaccgtcg
     7201 aggtctcgcg ccacgtcggg aacaccgact tgccctcggc gatcgaccac cacatgcggc
     7261 cgggccggga gaagtccgcg gtcggcggcg tgtagtaggc gccgacggca ccgccgggcg
     7321 gggcgatctt gcactcgagg ctcatcagcg cgtccggcag gtcgaagtgc acgtcgcgca
     7381 ggtcgagcag ggccttgtcg gacagttcct gcatccacgt ctgcaggccg tcctggccgt
     7441 gcacctggta gcgcgggtgc tcgtcgagga acgccgcggt ctccgccagc gaagcgcccg
     7501 gcttgagccg cgcggccacc ttcttcatct cggcctcgat gccgaggaac tcctcccagc
     7561 cccacgcgta ggcctcggcc aggtcgagcc gcgacccggt gaagtagcgc gagccgaggc
     7621 ggtagcgctc ctcgccgacc gcgtccttct gcggtgcttg cggggccagc gtcgtgcgca
     7681 ggaacgaagc gaagtccgcg taggcggcgg cagcggcggt ggcgccggcg tcgagagagg
     7741 aacgcaccga gccgtccacg tctgcggacg cggcgaacgg accgaagaag gtcgtcgcga
     7801 aggtgtcgca ctgcttggcg acctgagtga cctgacggat cgcggagacg tgtccgcggg
     7861 aagcggcgtg tgagagagag gcgcgcaggc cgtcgagagc ggcgggcacg gcggagagac
     7921 gacggccgat cgtggcccac tgttccggcg tgtcggtcgg catctggtcg aagatgtcgc
     7981 gcaccgactg gatcgggctc gcgatgacgt tcagcgagga ctcggtctca ccggcctcgt
     8041 acagctcgtg ctccaggccc gtccgttcca ggaagacggc gcgtgccgcc tcctccgagg
     8101 catccgcggg ctgtgcggcg gtgatggcgg cgagagcgcg gacggcgagt tcgtcgcgcg
     8161 ccgcgtgccc ttccggagag aggtccgtca gctggtcatc ggctcccgcg aagcccagac
     8221 tggtggcggt gatggggtcc agcgccacgt agtcgctgac gaatttgttg ctgatttcgt
     8281 gcacggatgc catgtttcga gacgctacct cgcgcccctc cacaccaaaa ggtagttagt
     8341 caagctcacg accttcggag gggacctgcg tcgtttgggc cgtgctggca ggatgtccgc
     8401 gtgcgtcgtt cccgggcact tctgctgccg gtcttcttgc tgctcaccct gttttcgttg
     8461 agcggctgcg ttcgcgtgta cgccgccatg gccgtgtcgg acgacgaccg catctccggc
     8521 gagatcgtcg cggccacgcc accgacccag gacaacgacc ccggaccaca gctcaaggtg
     8581 ccgccggagc tcgcgagccg cgtcaccacc aagccgtacc gggtggagtc gtacgcgggc
     8641 acgcagctgt tcttcaacgg cctgtcgttc gacgagatgc ggacgctgtc gacgtccacc
     8701 agctcgtcga acagccgcta cagcctcagc ttccgccggt cgggtgatct tgtcacgctg
     8761 tcggggtcgg tcgacctgac ccaggttccg gtggaacgcg cggacatcca ggtgaaggtc
     8821 agcttccccg gcaagatcgt gaacaccaac ggccgcgagg aggagaacaa cacgatcgcg
     8881 tggtctccga aacccggtca ggcgtcgatg ctgcaggcca ccgtgcagta cgcgggcgag
     8941 aactccagct cgttcttcgg ctgggcgctg ctggtcgccg ggctcaccgg cggtgccgcg
     9001 ctgatcgtcg tcgtgctcgc cctcatcgcg cacaagcgca acgtcacgct ctaagcgcgc
     9061 gtcaccaggc ccaggcgccc cagcacttcc ttcgtcgcct tggacctgtt catcgtgtag
     9121 aagtgcagcg cgggaacgcc ctcgtcgagc agccgctgac acatctcggt cgcgatgtcg
     9181 atgccggtcg cccggaaccc cgcgacgtcg tccgcgtacg gctccaaccg gcgcgagacg
     9241 tcgagcggca ggtcggcgcc ggacagctcc acgatcttgg ccaggccgcg cggcgagagc
     9301 atcggcatga ttccaggcag gatcgccgcg gaacagcccg cgtccgccac ccggtcccgc
     9361 atccgcagga acggctccgg cgcgtggaac agctgggcca ccgcgtagtc cgcgcccgcg
     9421 tcgagcttgc gcagcaggaa cttcaggtcg gtgtcgaggt cgccggagcg cgggtgcccg
     9481 tacgggaacg ccgccacgcc cacgcagaag tcgccgagct cgcggaccag acgcaccagc
     9541 tcgtcggcgt agttcaggcc ctccgggtgc gcgacccact cgcccatcgg gtcgccggga
     9601 gggtcgccgc gcagcgcgag gatgttgcgc acgccgatgg ccgcgtacca gccgatcacg
     9661 ttgcgcagct cggccaccga gtgctcgacg gcggtgaggt gcgcgacggg aagcagtgtc
     9721 gtctcctgcg cgatgcggcc ggtggcgcgg atcgtgcggt cccggcgcga cccgccggcg
     9781 ccgtaggtga tcgacacgaa cgccgggtcg aggccttcca gctcgcggac ggccttccag
     9841 aggatcttct cgtcctccgc gtcccgaggc ggcaggaact ccaccgagaa cttgggtgac
     9901 tctccccgga gccgctccac caccgacgtc ataggaccaa ccctagtggg tcttccgcta
     9961 ggtgagactc cagctcacca tgtggtacgc gggccccggc atgcgggtgg tcccggacac
    10021 agcggaccat ggacgtgtgt cccaccaccc catcgacgtc gcgttgcccc agcacgtcga
    10081 agcagcactg accacctatc tggcctcccg gcgcgcgtcc ggggaggcga tggacccgag
    10141 cttcgcgagc gcggtggacg cgctctccga tttcgtgctg ggcggcggca agcgcatccg
    10201 cccgacctac gcgtggtggg gctggcgagc ggccggcggc gaccccgacg gtgagctcgc
    10261 ggacgaggtg ctcacggcgg tcagctcgct ggagctgatc caggcgtgcg cgctgatcca
    10321 cgacgacctg atggacgcct cgtcggtgcg ccggggcaag ccgaccgtgc acatcgcgtt
    10381 cggcgcgcgg caccgcgagc agggctggct cggttcgtcg gagcgcttcg gcatgtcggc
    10441 ggcggtgctg atcggtgacg tcgcgctggc gtgggcggac gacatgctct tcgccgccgg
    10501 gctgccgtcg gaggtgctgc gccggatgag cgaaccgtgg cgggacatgc gcaccgagat
    10561 gctcgcgggc cagtacctcg acgtgctgac gcaggcgcgg ggcgactcgt ccgcggacgc
    10621 cgcgctgcgc atcgaccggc tcaagaccgc cgcctacacc gtcgaacggc cgctgcacat
    10681 gggtgcggcg atggcgggcg gctcgcccga gctgatcgac ggcctgcgcg cgttcggtgc
    10741 cgacatcggc gtcgcgttcc agctgcgcga cgacctgctc ggcgtgttcg gcgaccccga
    10801 ggtcaccggc aagcccgcgg gcgacgacct cgccgagggc aagcgcacgc tgctcgtcgc
    10861 gctcggcatg cagttcggcg ccgatatatt ggatatcgcc ctgggcaagc ccgatctcga
    10921 cctcgacacc gtcgaagagg tccggcgcac gctcgtgaag gtcggcgccg tcgacgccgt
    10981 cgaggaacgc atcgaggagc tgacgaagag cgcgctggcc gccctcgacg ccgctcccgt
    11041 ggccgaaccg gccgccgcca agctcgccgg cctcgcgatc agctccacca agcgcgcgtt
    11101 ctgaagttga tcacatttcc cgggcggacg gcttgattaa gtccacgtga ccagtgtggc
    11161 ccgttgcttg ccgacgcttc agcgccttgt gcaacgatgt tcgggcgatg gcagcaactc
    11221 cgtccctccc ccgcacgagc tccgaggcac ctctacagga gcttgatcca gtcgtgcgca
    11281 cgaacaccta cgccatcccc atccgcacga ccatgctcgg cctgctgggc gtggctctga
    11341 tcgcgctcgg gggcatgggt gccggcgcga tcctcgagcg cgacccactg ctcgcccagg
    11401 tcgggctgag ctggctgcgc tacggccacg gccgcgacct cgcgagcatg gtcctgtacc
    11461 tcgggctcgg cctcgtcatc tgggcgtgga tccggctcgg ccgtctcgtg cggtggggcg
    11521 agatcggcga cttcgcggtg ctggtcgcgg tgacggtctg gacgttgccg ctgctgttcg
    11581 cgccgccgct gttcagcaag gacatctaca gctacctggc ccagggccag ctcgcgctga
    11641 gcggttacga cccgtacacg gtcgggccgg ccgtcctgca gagcacgctg agcgagaacg
    11701 tcagctgggt gtggcagcac acgcccgcgc cgtacgggcc gttgttcatc ctggtcgcca
    11761 aggcgatcgt gtggatcacg gacgcgagcg tcatcctcgg cgtcgtcgcc atgcgcctct
    11821 ccctcgcggg cgggctggtg ctgctgtgct gggcgctgcc gggcctgagc aggcacctgg
    11881 gcggcaagtc ggcgatcgcc ttgtggctgg tcgcggcgaa cccgctggtg ctggtccacc
    11941 tgatcggtgg cgcgcacaac gacctgctga tgatcgggct gatggcggcc ggtgtgctgc
    12001 tggtgctcga ccgcaggcac gtgctcggct tcgtactgct ctccctcgcg ttctcggtga
    12061 aggcgacggc ggtcgtgatc gtgccgttcc tcgtctggat ctgggcggcg cgcctggagg
    12121 gcgacaagcg cgcccagttc cgcaaggcgc tgctgccggg cctggccacg ttcctcggga
    12181 cgttcctcgt gtgcacgctg atcgccgggg tgagcctcgg ctggatcccg gccctgcgca
    12241 gctcgtcgat gatcatcaac tggttgtcgc tgccgagcgc ggtcggtgac ttcgtgcgca
    12301 tggtcgtgaa ctggttcgtc tacgtcgacg gcggcatctt catcggcgtg gcgcgggcgc
    12361 tgggctccgt ggtgctgatc tggatcgcgt acacgcagtg gtgggcgtcc cgcgacggtg
    12421 aggtgcgcga cgccgtccgg cgtggcgcgc tgacgttgct ggccgtggcg ctgctgtccc
    12481 ccgcgacgct gccctggtac ttcacctggg cgctggcgct ggccgccggg ttcgcgtgga
    12541 gcacgggcgc gctggtcacg gtgacgaccg cgtcgctgtt cctgctgctg gtgacgttcc
    12601 cgaacggcga cacggcgctg tactcgtggg gctacctggc cttcgcgctg gtggtgtcgg
    12661 cgctcgccgc gcgttctttg gtgaagccgg acccgttcgg cctgtcctct cgttacgaat
    12721 gagccccggg accgtggacc tgggctccgc ctatgccgcc tgccgtcgcg tgaacgcgcg
    12781 gtacggcaag acgttcttcc tggccacgac gttgctgcgg cctgaccagc ggcccgcggt
    12841 gcatgccctg tacgcgttcg cccggtgggc cgacgagatc gtcgacgcgg ccggggtgac
    12901 cgaccgcgcg ggtgagctgg accgggtgga gcggctgctg gagaaggcgc cgtcgaaccc
    12961 gatcctgcac gcgctggccg acacgatgca tcgctacgac atcgacaggt cgctgttcac
    13021 ggacttcctc gcgtcgatgc ggatggacct cgacgtgacg gagtacgcgg acctcgacgc
    13081 gctcggcgtc tacgtgcacg gctcggcgga ggtcatcggg ctgcagatgc tgccggtgct
    13141 cggcaccgtc gtgccccgcg aggaggccga accgtacgcg gcccggctcg gggcggcgtt
    13201 ccagctcacg aacttcctgc gcgacgtcgg cgaggacctc gaccgcggcc gcgtgtacct
    13261 gccgcaggac gtcctcggcg cgcacggcgt cgaccgcgac cttttgcaat ggtgtcgtcg
    13321 tcatcgtcgc gcaaacgacc gggtgcaacg ggcgctcgac gacctcgtcg cgcactcgta
    13381 tgcgatatat cagtccgcgg agcccggcat cgggatgctg tccgcgacgt cccggccctg
    13441 tatgcagacc gcatacaccc tgtaccgcga catcctcggg ctcgttggct gcgaggtgtt
    13501 gtggcgacgt gtggccgtgc cgaactcacg gcggctcgcc gtggcggcgc ccggcgtcgg
    13561 ccgagccctc ctcgcccgtg tgacgactca cgggattccg gggtgagccc cgctctttta
    13621 gcctcgcgca gcggttccgg acgtctctca cctgcggaga cgtccggaac agctgtgatc
    13681 ggtgacttag aagcccatgg cctgcgcgcg gcgctttacc tcacgcccac ggtctccgcg
    13741 caatgcttcg atcggagtgc cagggaggct ttcgtcctcc gtgaagagcc agcgcaggat
    13801 ctcgtccgtg gagtagttct ggtcgcgcag caccgtgatg gtgccgggca gacccttcac
    13861 cacccctccg gcagcgagaa acgcctcggg gacgacgaga acgccggccc gccgctcggc
    13921 gagcagttgc ccgtcgcgca acatttggtg gacccgggtg accggaagtc ccattcggtc
    13981 ggccacctcg gggagaggaa gaacctccag gtcggcagcc aatacatccg cagcggcagg
    14041 aatcgcactc acgggggtca cgatgccata accgaactgg gaacgccctt ccgccaaccg
    14101 ggtcatcctg agctttacca tctcgcactg tggagaggtc ggtttcgaac gtgatgggtg
    14161 gactgctgga gcagcgctac cgggtggact ccgtgctcgc gcgcggtggc atgtccaccg
    14221 tctatcgagg tcgcgacact cgcctcgatc gcgatgtggc catcaaggtg atggatccgc
    14281 acctgacggc ggacccggcg tttgtcgcgc gcttcgagcg cgaggcacgc gcggcggccc
    14341 agttgcacca cccggcagtg gtgtccgtgc acgaccaggg cgtcgacggt gaccaggtgt
    14401 acctggtgat ggagctgatc gacggcggaa acctccgtga cctgctcaat cagcgcggca
    14461 agctcgctcc cgccgtggcg ctgagcatcc tcggcccggt gctgtccgcg ttgggcgcgg
    14521 ctcaccgcgc ggggctcgtg caccgggacg tgaagccgga gaacgtgctg atcggacccg
    14581 gtggccaggt gaaggtggcg gacttcgggc tggcccgtgc gatcgccgag aacggcgtca
    14641 cgagcgacag cgagatcctg ggcaccgtcg cctatctttc acccgaacag gtggaatcgg
    14701 gcgctgcgga cgcgcgtagt gacgtctacg cggccgggat cgtgctctac gagatgctgg
    14761 cgggtcaggc gccctatcgc ggcgagacgg ccatctcggt ggcctatcag cacgtgaact
    14821 cggacgtccc gtcggttccg gagatcccgc tggcgctcga cacgctggtg cgcaaggcga
    14881 cgcggcgcga cccggtgctg cggcccgcga acgccgacgc gttcctggcc gaactggagc
    14941 gcgtgggcac ggacctgggc ctcacgccgc agccggtgcc cgtacccggt tcggcgcccg
    15001 agaacgacag gacggtcatc atgcgaccgg ttccggtcgc ggtcggcgcc actcctccct
    15061 ccgctgccga gctgaccagg ccggtggtgc cgaagccgtc cctgaactcg gcggcgatga
    15121 cgacggtgag caccgggccg ccgccgcctc ctcccggtat ctccggcacg cgcacgatgc
    15181 agcggccgga gccgccacgc cgtcgtcccc cgcagaagaa gaagccgaag gtcgacccgg
    15241 tcgaggagga gcgcaagcgg cgcaagaagc tcttcacgat ctggggttcc gtggtcgtcg
    15301 tggtggcgat catcgtcggc ctgttctcct ggtacgtcgg cgcgggccgc tacacggaga
    15361 tgccgtcggt ggccgggcag tccgagcaga acgcgatggt gctgctctcg aaggccgacc
    15421 tcaccgggct ggtcgagaag gtgccgtcca acgacgtgcc caacggcacg gtcatcagct
    15481 ccgaccctgg tcctggcgcg gagctgcgca agaaccagca ggtgaagctc gtcgtgtcgc
    15541 gcggcaggcc cgtggtgccg ttcatcaaca ccggcgtcga cgaggccgcc gccaccaagg
    15601 acatcgaggc cgcgggcctg aaggcggtca aggacgccac gaaggacgcg ttccacgaca
    15661 ccgtgccgat cggcaaggtc gtgggcgtcg atccacgccc cggcacggcg ctcgctctcg
    15721 acgccccggt gacgctgatc ctgagcaagg gaccgccgcc gcgcctgccc gtgccgaacg
    15781 tgacgggcaa gacgaaggac gaggcggtcg ccgaactcca gcgcgccggt ctggaagcgg
    15841 tcgacgcggg tggcgaggac gcgccggaga acaacgggtc gcgcgtggtg cggacggatc
    15901 cgccggcggg caccgtgctg gacccgacgc agaacaagcg cgtcacgctc ttctaccaga
    15961 acaaccagga gatcgaggtt cccgacgtca cccggcagaa ggtgcgggag gccaaggagc
    16021 agctcgaaca ggccggtctg cgggtgaagg tcgagttcaa caagagcaac aacgcgaccg
    16081 tggtgaacca gtcgatcccg ccgcgcacgc gggtgaagcg aggaaccgag atcacgatcg
    16141 tcggcctctg atcacggcaa aggcgaaggg ccccgcgttc tcgacgcggg gcccttcgtt
    16201 cttcagctcg tcttcaggaa actcgtccgg aaggtgttac gaccggagca tctcggcgac
    16261 gaggaacgcg agctcgagcg actgctgcgt gttcaggcgc gggtcgcacg ccgtctcgta
    16321 gcggccggcg aggtcgtcgt cggagatctc ctgggcgccg ccgaggcact cggtgacgtc
    16381 ctcacccgtg agctcgatgt ggatgccacc ggggtgcgtg ccgaggcggc ggtgcacctc
    16441 gaagaagccc tggacctcgt cgacgatgcg gtcgaagtgc cgggtcttgt agccggtcga
    16501 cgactcgtgc gtgttgccgt gcatcgggtc gcactgccag atgaccttgt ggccgctggc
    16561 ctcgaccttc tccacgatgg cggggagcac gtcgcgcacc ttctggttgc ccatgcgcga
    16621 gatgagcgtc aggcggcccg gctcgttgcg ggggtcgagg cgctcgacgt actcgacggc
    16681 catctcgggc gtcgtcgtcg gaccgatctt gagaccgatc gggttcgaca gcatctccgc
    16741 gaacgcgatg tgcgcgccgt cgagctgacg ggtgcgctca ccgatccaca cgaagtgcga
    16801 cgacaggtcg tacaggcggg gctcgtcgcg cgtcgtgtcg aggcgcagca gcgcgcgctc
    16861 gtagtcgagg agcagcgcct cgtgcgaggc gaagatctcg gtgccgtgca gcgactggtc
    16921 gttcacgccg cacgccgaca tgaacttgag gccgcggtcg atctcgccgg ccagggcctc
    16981 gtagcgctcg cccgcgggcg aggtgcgcac gaagtcgcgg ttccagtcgt gcacgcggtg
    17041 caggtcagcg agacccgcgc cggtgagcgc ccgcagcagg ttcatggccg cgccggcgtt
    17101 cgcgtaggcg cggatcatgc ggccggggtc ggcgacgcgg gcttcgggcg tcgctaccag
    17161 ggagttgatg atgtcgccgc ggtaggacgg caggccgaga gcgtcgatgc ccgacgaacg
    17221 cggcttggcg tactggccgg cgatgcggcc gaccttcacc accggaaggc tcgcgccgta
    17281 ggtcagcacc acggccatct gcagcagggt ccggatgttc gcgcggatgt gcggctcggt
    17341 gttgtcagcg aacgtctccg cgcagtcacc gccctgcaga agaaatgcct caccgttcgc
    17401 gacctgcgcc agttgcgtgt gcagccggtc gatctcggcg ggcacggtga tcggcggcac
    17461 gctctcgagc acggtccgca cgcgacgcac ctgttcggcg tcgggccagt cgggctgctg
    17521 ggcggccggg cgcgacagtg cgtcgtccag gcgcttgcgc atctcgggag gcagcggcgg
    17581 aagctcggga agcgtgtcga tgggcacgtc cacggtccag ttcacgctgc tcatcctagt
    17641 tgtcccacac tgagagaccc tgccgggcct gtcagctgtt cagcacgtgt tttccaggtc
    17701 acccgcccgt gtgccgatcc tccgccggcg gcgtgaggtc tgttacttgt caactatctg
    17761 cctctgccct attgagatgt cgcactgcat gatgtgggcc atggacgcca cccgattgga
    17821 tgacagcacc gcgacccggc tgctgggcat cgcgatcgac aacatccaac gcgaccaccc
    17881 ggtgcactgg acgcacgtga tcgacggaga ccacggcctg gtgccccagc gggtgctgca
    17941 cccggtgttc gccgggtcgt tcgactggca ctcgtgcgtg caccagacgt ggttggccgt
    18001 gcgcttgctg cggctgcggc cctctctcgc gggagcggac acggcccgca acgccctgga
    18061 caagctgatc acgcccgaga actgcgccgt cgaggcctcc ttcttcgcct cccgggccgg
    18121 acggcactgg gagcggccgt acgggtgggc gtggctgctg ctgctcgacg ccgagctgcg
    18181 cacctcgggc ctgccgtggt cggtcgcgcc gatcgcggac gtgctgcgcg accgctggct
    18241 ggaatggatc tcggcggcgc gcctgccgat ccgcaccggc acgcacagca acaccgcgtt
    18301 cgcgaccgga ctcgtgtacg acaccgccca ggtgaacggc gactccgaac tggcctccgc
    18361 gtgcgtcgac gcggcgctgc gatggcaccg ggacgaggcc ggatacggcg gcttcgaacc
    18421 ggacgccgcc gacttcctct cccccgcgct gacaacggcc gacctgatgc gccgcgccct
    18481 gagcaccgcc gagttcgccg actggttcga cgcctacctg ccggacctcg agtcggaacg
    18541 gtggcgggtg ctgcgcgagc cgtatccggt cgacgacccc agcgacccct acggctcgca
    18601 cctggccggg ctcgcgttgt cgcgcgcctg gaactgggag gcgatcgctg gggcgctccc
    18661 ggacggccac cgctacacct cgctggcccg gacggcttcc gccgcgcatc gtgaggccgg
    18721 gtggacgtac gtgttcggcg ggcacggcta catggccgac cactggctcg gctcgttcgg
    18781 cgcctacctc gacgcaaagg ccttctgacc tgcacttacc cacccattgc aaaagacgtt
    18841 tgcggacgtc cgcaaacgtc ttttgcataa gggcggacaa aacgggcacc gatatattgg
    18901 atttcaggtg cctgacgaca acgtcgcgcg ccggatcagc gtcagggcga tgcccgtcgc
    18961 cgccgcgtgc accgaagccg cgtgcacgcg agggtcgaac cgcgtggtcg gcccggcgac
    19021 actgaccgcg gccacaacgg caccgtcgtg accgagcacc ggcgacgcca cacaggcgag
    19081 gccgaccctg gactcctcga actcgtaggc cacccccgtc tgccggatcg tggccagctg
    19141 acgccggagc atgccgggcg tgacgactgt gcgcggagtc cggcgagcca agggggcgga
    19201 caggacttcg gtgcgcaagg acggctggga gtgggcgagc agggccttgc cgatcgccgt
    19261 cgcgtgcagc ggcatgcgac cgcccagacg cgacggtgag gacgcctggc ggtggccgcc
    19321 gatcttggcg gcgtagacga cctcgtggcc ttcgaggagt ccgaggtgga cggtttcgtg
    19381 ggtgcgttcg tagaggtctt ccaggtaggg cgtggacacc tcgaccaggc ggcgttcgac
    19441 cgacgcgcgg atgcccagct ggaacaggtg accgcccagg cggtagccgc gcgtgccccg
    19501 gtcgagcagg cggacctcgg ccaggtcgcc cagcaggcgg tgcagcgtcg ccttcgacag
    19561 gccggtgcgt ctgcccagtt ccgcgaagcc gagctcgtcg tcgtcggcac cgaaggcgtt
    19621 cagcaccgac atcaccttgc ccagcagggt gttcggtacc tcggtcatca cctgatcgtg
    19681 ccaccgagtt ccggtcagcg gaactccgaa gtccccacag gaccgagaac accgccacga
    19741 tgagcggcat gaacgaagtc ctcattgcag cggagcgcct ggccacggcg gcgcgcgaga
    19801 aggttccgtg tgcgcccgtg cgggacctca tcggcgacgc cgaggcctac gcggtgcagc
    19861 agcacaacat cgccgcgcgg atcgcggacg gcgccacagt cgtcggccgc aagatcggcc
    19921 tgacctctcc ggcggtccag cagcagctcg gggtggacca gccggacttc ggggtgctgc
    19981 tcgacgacat ggcgtacaag gacggcgacg aactgccggt gtccggtctg ttgcagccga
    20041 agatcgaggc ggaactggcg ttcgtgctga aggcggacct cgccgagggg ccgttcgacg
    20101 agcagaccgt cgcgaacgcc gtcgggcacg tcaaggcatc gctggagatc gtggacagcc
    20161 ggatcagcgg ctgggacatc accttcgccg acaccgtcgc ggacaacgcc tcgtcggggc
    20221 tgttcgtcct cggcaccgag caggcggatc tgggtgaggt cgtgccgaag aacgtgtcga
    20281 tggtgctcag cgtcaacggc gaggaacgtt cggcggggtc cggtgccgcg tgcctgggcg
    20341 acccgctgac cgcgctggcc tggctcgcca cgaccgccgc ggacctcggc gctccgttga
    20401 aggcgggcga cgtcgtgctc agcggcgcgc tcggcccgat ggtcggagtc caggcgggcg
    20461 accaggtcga ggccacgatc accgggctcg gcaccgtgcg ggccactttc gcgaagcagg
    20521 aggcgtgatg cgcacgaagg tcgcgatcat cgggtcgggc aacatcggca ccgacctcgt
    20581 catcaaggtg ctcaagcggt ccaccaccct gcaggtggcg gcgctcgtcg gcatcgaccc
    20641 cgagtcggac ggcctcgcca aggcccgcaa gctcggcgtt ccgaccactt cggacggcat
    20701 ccagggcctg gtcgcgatgc cggggttcga agagatcgag atcgtgttcg acgccacctc
    20761 cgcgggcgcc cacgcgaaac acgccgaaat cctcgccgcg cacggcaaac gggtcatcga
    20821 cctcaccccg gcggcgatcg ggccgatggt ggtgccgacg gtcaacctcg acgaacacct
    20881 gagcgcgccg aacgtcaaca tggtcacctg cggcggtcag gccacgatcc cgatcgtcgc
    20941 cgcgatcaac acggtcactc ccgtgccgta cgcggagatc gtcgcctcga tctcgtcccg
    21001 aagcgcggga ccgggcacgc gcgcgaacat cgacgagttc accgagacga ccgcgcaggc
    21061 catcgcggac gtgggcggcg cgcacagggg caaggccgtc atcgtgctca acccggccga
    21121 cccgccgatc accatgcggg acaccgttct cgcactcgtc aacgcaccgg atccccagac
    21181 acagcaccgg atccgcgcct ccgtcgagta catgatcacc caggtggccg cctacgtccc
    21241 cggctaccgc ctcaaacagc cggttcagat cgacccggtc gaccagccgc acacgctcac
    21301 cgaggaaccg gtgacgcacc aggtcaccgt gctgctggag gtcgagggcg cggccgacta
    21361 cctgcctgcc tacgcgggca acctggacat catgaccagc gcggcgctgc gagtcgcgga
    21421 gaccatggcg aaggcggtcg tgcgcgcatg aagatctacc tccaggacgt gacgctccgg
    21481 gacggcatgc acgccctgcg gcatcgcatc gatccccaga aggtcaccga gatcgccagg
    21541 gcgctggacc aggccggagt cgatgccgtc gaggtctcgc acggcgacgg cctcagcggc
    21601 ggatcgctcg tctacggccc cggcagccac accgactggg agtggatcga ggcggccgcg
    21661 gaagcgttga cccaggccaa actcacgacg ctgctgctgc cgggcatcgg cacgctccac
    21721 gacctcaagc gcgcccacag ccttggcgtg cggtccgtgc gcatcgccac gcactgcacc
    21781 gaggccgaca tctccgccca gcacatcgcc ggcgcgcgcg atctcggcat ggacgtgtcc
    21841 gggttcctga tgatgagcca cctcgccgaa ccgcaggagc tcgctcggca ggcgaagctg
    21901 atggagtcct acggcgcgaa ctgcgtctac gtaacggatt ccggcggccg tctgctcccc
    21961 cacgacgtcc gcaccaggat ccgtgcctac aaggacgtgc tcgacgccga caccgagatc
    22021 ggcatccacg cgcacgagaa cctctcacta gcggtggcga actccatcac cgccgtcgaa
    22081 gaaggcgcta cccgagtcga cgcctccctg gccggactcg gcgccggagc ggggaactgc
    22141 cccatcgaac cgttcgtggc cgtcgcgaac ctccaggaat ggcagcacaa cgccgacctg
    22201 ttcgcgctcc aggacgccgc cgacgacctg gtccggccgc tcatggaccg cccggtccgc
    22261 gtcgaccgcg agagcctcac cctcggctac gcgggcgtct acggctcgtt cctgcgccac
    22321 gccgacacgg ccgcccaacg caccggcgcc gacgtacgga ccctcctgct ggaagccgga
    22381 cgccggcgct tggtgggcgg tcaggaggac atgctgaccg acatcgccct ggacctcaca
    22441 cggcaaacgt agttccgata cccatgccgg tgatccactc gggcaccggc tcgtagctcg
    22501 tccacaccag cggcaggccg acagcgacct gtccgatgag ccagcagcgg atctcgtgcc
    22561 caccgctgcc ggcgtggtcc tccagcgcct cgtgcccgag ggaggcgatc tcaccggcag
    22621 accccgccga cagccggtcg aggaaccacc cgtcccacac cgcgttcacc ttcgcctcgg
    22681 ggttgccgcc catggccttc acccgaggct cgcgcgccgc ggcgaactcc ttcgcgtacg
    22741 cccgtccccg gatcaacgac tcacgccgct cccccaccac ggacggatcg cgcgggtcgt
    22801 tggacggcaa ccagtgcgac aagccaccac tggcgacgac cagcacccgt ccgggaaaca
    22861 ccgacgaccg cagcgcggct cccaaagcac gccccagctc cacgcacctg tccagcgacg
    22921 gcaacggcgg cgcggccgtg ttgaccacca acggcaccaa cggaagcgtc gtaccgccgg
    22981 tgatcatctc gtagctctgc acgatgccgt ggtcgacggt cagcgagtac gacagcgaca
    23041 cgtcgaagcc cgcgtccgcc agaccgctgt gcgccgacca ggccagcgtc tgggccaccg
    23101 gtaacggccc cgagctgctg ccgaagtcac cgaaccccac ggcttcctcg accccgagca
    23161 cgaacggcgg catcacgtcg tagaagttgg cgtggaagtg gtccggcccg atcacgacga
    23221 tcgcgtccgg cgccagcttc tccaccgcca gccgcacgcg gtccgcgtcg cgcaggaaca
    23281 ccgaccccgg cccgtcggag ccgtccggtg gcagcagcgt cgcgaacggg ctgtgcgaca
    23341 tccccgcgaa tccgatgatc tctgccatca ggacgggtcc tttccgtgca gcaaccaggt
    23401 gcggtgcgtg tcgaggaact cggagacctt ctcccactgc ggccagtgcc cggcgtcgtc
    23461 gatgacgtgc aaccgcgcgt cgggcaacca ctccagcaac atgtcggcct cgtccagccc
    23521 gcccgtcggg tcgtggctcg tccacagcag cagcgtcggt gccgcgacct tgcccaccca
    23581 cgccgggtcc cacgcgaagt ccttgc
//
