LOCUS       NZ_FOYL01000006        22154 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea waywayandensis strain DSM 44232, whole genome shotgun
            sequence.
ACCESSION   NZ_FOYL01000006
VERSION     NZ_FOYL01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea waywayandensis
  ORGANISM  Lentzea waywayandensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900115955.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:54:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,449
            CDSs (total)                      :: 9,363
            Genes (coding)                    :: 9,244
            CDSs (with protein)               :: 9,244
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 26 of 119
            Pseudo Genes (incomplete)         :: 101 of 119
            Pseudo Genes (internal stop)      :: 5 of 119
            Pseudo Genes (multiple problems)  :: 12 of 119
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:39:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 175034
            Orig. end                         :: 197188
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOYL01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22154
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22154
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22154
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12154](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12154
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            10..135
                     /locus_tag="BM417_RS49900"
                     /old_locus_tag="SAMN04488564_106183"
     CDS             10..135
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950189.1"
                     /locus_tag="BM417_RS49900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106183"
                     /product="hypothetical protein"
                     /protein_id="WP_281251347.1"
                     /transl_table=11
                     /translation="MSSPLENRSSTVLLIGAWLWVGLPLAYGLYRLFLNAAKLFV"
     gene            135..2213
                     /locus_tag="BM417_RS24015"
                     /old_locus_tag="SAMN04488564_106184"
     CDS             135..2213
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019974.5"
                     /locus_tag="BM417_RS24015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106184"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_093598528.1"
                     /transl_table=11
                     /translation="MFNALVNWRNWRLPVKLAAVLIVPVTIAVGSGVLQINSQIDRAES
                     YAALQRLVKVRAALIPVIEGVQAERRIVAEGVGPQLLAEQAKRTDDARAALRDEIAKTS
                     LGEVVTARMSDVQGRIGDLAALRERTDDVPAVIKTYSELTESLLDVDEVIASEFGDAAL
                     LRTAMGLHHVVHVRDQVLYQQAVVLSGLTRGQLTTAEVRALVESNVKLGYIAGEFAALA
                     TSDQLKTYGKNFNGPDIEAQRTMLAAAVLHPTSDAPSTGNNRPRPLPIAAADWTKASGA
                     VVTSMDGVVQGLQNDLRDTANRLRDESSDAAGTASAILFASLILAGTIGFVVGRYLLRS
                     LNALRRSALDVAWEKLPEMVATGRGSTEIERVPVDTTEEFGQVARAFDEVHQQAVKSVI
                     EQAGMRANMRNIFVNLSRRSQSLVERQLKLMEELEKYEEDPDQLANLFKLDHLATRMRR
                     NNENLMVLSGGDVARRFHKPIPLTDVLRAAAAEIEQYQRVMVHTAPNAEVVGYVASDLV
                     RLLAELLDNATAFSPPHTQVSISASIEAGDIVQIDVVDHGIGIDPEALAGVNQRLEAAG
                     EGMDVQVFREMGLFVVGRLAARHQIVVRLDAKQGQGTRAIVLVPAELAPRREESWESFR
                     GETIERQQASWFQQTTPAAAPPPPPAPARQTPESARGFLDAFQRGVQRGLPDHQESR"
     gene            2210..2608
                     /locus_tag="BM417_RS24020"
                     /old_locus_tag="SAMN04488564_106185"
     CDS             2210..2608
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501899.1"
                     /locus_tag="BM417_RS24020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106185"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_093598531.1"
                     /transl_table=11
                     /translation="MSTQVDQFGWLVTNFAERTPGIEHAVVISADGLVLISSSKLPEHV
                     APQFAAIVAGVVSLADSASKCFAGESVVRTVVQMDRGVMLLSAISDGSVLAVLASSSAD
                     VAQIAYEMTVVVRQVGQLLTPELRAELA"
     gene            2605..3138
                     /locus_tag="BM417_RS24025"
                     /old_locus_tag="SAMN04488564_106186"
     CDS             2605..3138
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010305141.1"
                     /locus_tag="BM417_RS24025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106186"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_093598534.1"
                     /transl_table=11
                     /translation="MSREPDDQVNFGDLISGFSFDSERIRKRGKKKGQRAPEPPPEQPD
                     PYATAPFEPVPPLPSIEDGIDTSSSIVRAYAWTGGRTTSDVHLEIETLVSVNEFSATAV
                     RPEHQDVLALCSQPRSVAEIAALRGLPLGVTKVLLGDMAGHGLIDVHRTASSYGGDRPD
                     GMLLERVLAGLRRL"
     gene            3196..3783
                     /locus_tag="BM417_RS24030"
                     /old_locus_tag="SAMN04488564_106187"
     CDS             3196..3783
                     /EC_number="1.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005166896.1"
                     /locus_tag="BM417_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106187"
                     /product="nitroreductase family protein"
                     /protein_id="WP_093599294.1"
                     /sec_met_domain="PF00881 (E-value: 1.7e-18, bitscore: 62.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFQDVVRRRRMVRKFTDEPVSEESVQRIMRNAVRGPSAGFSQGQ
                     GFLVLQGEPLKRLAEMFEWWGGEEAKTAPVVVIPFSSKQVYLDRYAQPDKAWAGLTEER
                     WPVPYWDIDTGMAALLILQTAVDEGLGAVFFGTEKETWPELRAAFGVPDTYVPIGMIAI
                     GHSAEEGVSEGASPLRRKRKAFDEVVHWGQWT"
     gene            3774..6707
                     /locus_tag="BM417_RS24035"
                     /old_locus_tag="SAMN04488564_106188"
     CDS             3774..6707
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="BM417_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106188"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_218164539.1"
                     /transl_table=11
                     /translation="MDVRSFGLLGPLDVVLDGRHVHIPPGKRRVVLAALLLRPGQVVGV
                     DELVELAGGSRNALQTTVGRLREVLPGLVLTKPGGYLLDVLPDEVDVHRFDRLEPREAL
                     ALWRGRPFADIGSDALERDHVPALTEKYLATLEARIETDLRDGEHERLVPELRSLTRQN
                     PTRERMWAQLIVALHRCDRQTEALQAYDDIRGRLAGELGLDPGKDLQKAHQQVLTADNR
                     PRARNDLPGDIADFAGRASDLDEILAAVPSGCVAITAIDGMAGIGKTTIAVRAAHRLAA
                     RFPDAQLFVDLHSYTAGVEPRTPSDALLALLTALGVPAQDIPDGLDARAARWRAEMAHR
                     KALVVLDNAGSTSQVRPLLPGTGLVLVTSRRRLVDLDAAHTISLDVLSEADSLNLLASI
                     IGRAKLDQDVDSAREIVRLCGYLPLAVRIVGARWRTRPAWSAQDLTRRLTGQRLSELTA
                     GERSVADAFTLSYQQLTPEQQRLFRRLGLHTGEDFDAYLAAAVVGTTRAEAERLLEELL
                     DAHLVQQKENGRYRFHDLLADHAKASVEEDERVEAVTRVLDHYLHNAAASAQKIAPGRP
                     QIHSAATYVPVDPPLFATPVEALAWQETERSNLRAAVYLAAYEGYYQHAWQLPHHFAHF
                     LLLRGSGRERVEVQSVALAAARHLGDLKARAEALRGLGSAYKDDNNPKAEEHLREALGL
                     MRQIGDLRGEASTLGLLGMIARERREYDKAMLYFERGVVLMRHVGAQTGEANALHNIGI
                     VHAERGETGQALAHLQEAVTLLEAHGDVRASAMTLHDMAHVHFDAFNDEESLNFSERSL
                     AAYRESGDRRGEALALADFAYWRYAMGDLAAAGRTAREVGRLCRAYMILPDDHAVLAAM
                     EDVRDHFGQVALLVSLSLDAHAAGRLSEALGHVRRCLAVVRSTSQWWSENRLLGQLSTL
                     HLALGDRDAAVRYGEKAVTAAEQLGQPRAVAVAKQALATASAPAPPA"
     misc_feature    complement(6874..6888)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.74"
                     /tool="antismash"
     gene            6917..8947
                     /locus_tag="BM417_RS24040"
                     /old_locus_tag="SAMN04488564_106190"
     CDS             6917..8947
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="BM417_RS24040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106190"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_093598540.1"
                     /transl_table=11
                     /translation="MQTALFPRPHQLPAAVADFVGREELLQSVVDRIIPFAQVVLLTGP
                     VGTGKTTLAVHAAHRVANGHFPDGQLFVRLRGTTPYEVLGRFLTAFGLPAPGDFAARLS
                     AYRDAVVRQSLLLVLDDATCVDQVKPLLPHAPGCAVLVTSRHTLKLPHVVEVGPLEPAQ
                     AMMLLGNQIGPDRLAAQDAGELVAASDCLPLAVRIAGAVLAARPHWPLALLTDRLRESR
                     LEALSYGGLSVRARLEETAGDLSPPARRLLGLLADVGARRLPSWAPVAAFGDVRGQSAV
                     DELVSAHLVSVSEDGYAVPELVREFAAGRSDAGEALRRVLGGWLYLLDQARTALYGGDF
                     SVIRGCSAREVVRPDRALRADPLAWLESERESLCDAVDLAAEADLDEPAWELAHRLVTF
                     FEARTDFEGWQHTHDIALAACERAGNRRGAAVLHCSLASLHISQSRYDLAHEMTLRAKD
                     FFEDHDDLAGLGLVYRNLGIVARSSGELAAARRWYQRALAVYERFTDPVGEASVLQNLA
                     QIDLYDGDPAGARERLSAALAACDGAGPARVLAQINYRLGKLLAVDGRHDEAFDVLTVA
                     LDLARTARDRRGESFVLYALGRNEFARCRMGPARTLLREAAALCEANFDVVGAARARLE
                     LSRVHQACGEVQLAAELEAAARAVYSEFGLKPVLGDLIFQP"
     misc_feature    8997..9015
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     misc_feature    complement(9045..9054)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.31"
                     /tool="antismash"
     misc_feature    9050..9064
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.89"
                     /tool="antismash"
     misc_feature    complement(9060..9074)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.72"
                     /tool="antismash"
     misc_feature    complement(9061..9075)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.1"
                     /tool="antismash"
     misc_feature    9064..9080
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.63"
                     /tool="antismash"
     misc_feature    complement(9067..9076)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     misc_feature    complement(9215..9231)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.57"
                     /tool="antismash"
     gene            9308..9856
                     /locus_tag="BM417_RS24045"
                     /old_locus_tag="SAMN04488564_106191"
     CDS             9308..9856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098743.1"
                     /locus_tag="BM417_RS24045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106191"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_093599297.1"
                     /transl_table=11
                     /translation="MGGVPTFPHGRPLTWADLEAMPDDGHRFELVDGVLVMSPSPRPVH
                     QRVVARLLVALTAVCPPELEVLPAPVDVVLADDTVFIPDLVVGRREQFSKQALIGPPVL
                     AVEVLSPRTRHVDLELKRAKFQEVGCENYWMIDYDSPWLRCLHLENGVYVEQARSDGEE
                     IIELQFPFAVKLSAQSLVR"
     gene            10001..12154
                     /locus_tag="BM417_RS24050"
                     /old_locus_tag="SAMN04488564_106192"
     CDS             10001..12154
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948856.1"
                     /locus_tag="BM417_RS24050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106192"
                     /product="terpene synthase family protein"
                     /protein_id="WP_093598543.1"
                     /sec_met_domain="T1TS (E-value: 1.3e-74, bitscore: 247.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPFQLPEFYTPHPARLNPNLERARVHTRAWAHEMDMIDVPQHGT
                     VIWTDDDLESHDYALLCAYTHPDCDGETLDLVTDWYVWVFYFDDHFVELYKRNPDIKGA
                     QAYLDRLPLFMPVNGVITETPTNPVEKGLADLWRRTVAKHSLDWRERFASNTKHLLDES
                     MWELHNISAQRLSNPIEYIEMRRKVGGAPWSANLVEHAVGLEVPAPIALSRPIGVLRDT
                     FSDAVHLRNDLFSYEREVLDEGELSNSVLVFEKFLDIPTQDAAEAVNDLLTSRLHQFEH
                     TALTEVPILLDEHAIDPIGRAAVLGYVKGLQDWQAGGHEWHLRSSRYMNKGAKTGLSAT
                     NILGSYAKTMPQRLKQFSSTPKVVEPYTLPEFKTPFTLTLSPHLDQAREEVITWGREMG
                     IHDEGIWDEAKHRGFDLALCSSGLDPDATPEELFLSAAWLTWGTYADDVYPWVFGRLRD
                     LAGLKIQTARLKQCMPLDMVLTVAPVNAMERGLADLWQKTAGPMSGEFGATFRQTVDDM
                     VDAWVWEVVNIQQNRVPDPVDYLEMRRSTFGSELTTSLSRFSHSTTVPPEIWGTRVIQT
                     MERSAMDYCCLLNDVFSYLKEIQYEGEVHNMVKVIENFLGVSQSRAFELTYALMDARLG
                     QFIASVDTHLPKMFDDLSLDSATRASLTRYADELKDWIVAIINWHKGTSRYGEDEIRTP
                     VNSGAFSQGPSGIGTSAARLLAR"
     gene            12245..13333
                     /locus_tag="BM417_RS24055"
                     /old_locus_tag="SAMN04488564_106193"
     CDS             12245..13333
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100554.1"
                     /locus_tag="BM417_RS24055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106193"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_093598546.1"
                     /transl_table=11
                     /translation="MKNVLISGASIGGPALAYWLRRNGFSVTVVERSRGMRPGGQAIDV
                     RGPALEVIERMGLGDQLRSFSTNMRGMNVVDADGNELFRSTTHTLSGGDLSSPDVELLR
                     DDLARMLFDAADGVEYLFDDTITSIDGTRVTFEKAAPRDFDVIVGADGLHSNVRRLVFG
                     PESEFITHLGMNLAVFTAPNFLGLDHWQTFQQGEVVGGGIMSARSNAECRVYMGFNGVT
                     DFDHRDVDAQRTLIAEKFADAGWAWPTALKHMWEAPDFHFDSMSQIRMDSWSRGNVVLL
                     GDAGYCGSPLSGQGTSMALVGAYVLAGELAKDPSTAFQRYEEILRPYVIANQDMALKNQ
                     ANGGAPTEEFTDVVNSLTLPAY"
     gene            13462..15162
                     /locus_tag="BM417_RS24060"
                     /old_locus_tag="SAMN04488564_106194"
     CDS             13462..15162
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016697585.1"
                     /locus_tag="BM417_RS24060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106194"
                     /product="family 20 glycosylhydrolase"
                     /protein_id="WP_281251351.1"
                     /transl_table=11
                     /translation="MAVTAALSVSAQSQAAEPLQSLVPVPVSVQARSGVTHTLTAATKI
                     YTAPAARDVGTFLAGVLRPSTGYALPVSDATGTPADGISLLLSGAPGTVGDQGYQLDVA
                     ANSIVLRANTSEGLFTGVQTLRQLLPAKVESTTAQTGPWTVPGTVIVDYPRFSYRGAML
                     DVARHFHPVSTVKRYIDQLALYKINYFHLHLSDDQGWRIVVDSWPRLATYGGSTQVGGG
                     PGGYYTKAQYSEIVQYAASRKITVIPEIDMPGHTNAAQASYAELNCNGQAPPLRTDIEV
                     GYSSLCVNKEITYQFVEDVVREIAALTPGPYFHIGGDEAHATSDADYQTFMNRALPIVK
                     KYGKTVLGWHEFVKTTTDTTAIPQYWGTSTSNATVQAAVARGNKVIMSPANKAYLDMKY
                     NSSTPLGLSWAGLIEVQTAYEWNPGTHLSGVPESAVRGVEAPLWTETLVTGRDIEFMAF
                     PRLGAIAELAWSPWSTHNWDQFKVRLGNQGPRWTTMGINFYRSTQVPWDTGGPGPGPCT
                     QPAWERDKVYTGGNVVSHNGHKWTAQWWTRGEEPGTTGQWGVWRDGGVC"
     gene            15224..15970
                     /gene="surE"
                     /locus_tag="BM417_RS24065"
                     /old_locus_tag="SAMN04488564_106195"
     CDS             15224..15970
                     /EC_number="3.1.3.5"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004309 - exopolyphosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008254 - 3'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0106411 - XMP 5'-nucleosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="surE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229561.1"
                     /locus_tag="BM417_RS24065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106195"
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="WP_093598552.1"
                     /transl_table=11
                     /translation="MRVLVTNDDGIDSPGLYALARAASSLGWEVLVAAPSTEASGTGTS
                     LASASGRSRIPLERRQVDGFEAFAVPGHPALISFIACQGGFGERPDLVLSGVNLGANTS
                     TGILHSGTVGAALAASARGVSALAVSLDVEWDGSAPLWDTATDVARAVLPMLAEMPAAT
                     VLNLNVPNAATVRGIEWADIAPSSPYQVHFESNGDELKLRAVKTDLEPVPGTEIAFLAD
                     GYAALTPLRSVAAASTSGLPSPAWPA"
     gene            complement(15933..16262)
                     /locus_tag="BM417_RS24070"
                     /old_locus_tag="SAMN04488564_106196"
     CDS             complement(15933..16262)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS24070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_106196"
                     /product="hypothetical protein"
                     /protein_id="WP_093598555.1"
                     /transl_table=11
                     /translation="MALLSDQFEFTRPQALTLTAGLLQLAFGWFDVFGLDPNYHVIQIG
                     VGALGVAMAWRHDLARMYGILLLVSFGTLAFSLNDVTTESFLEVRTALIGLVITLARPA
                     KADRT"
     misc_feature    complement(16194..16196)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16269..16664)
                     /locus_tag="BM417_RS24075"
                     /old_locus_tag="SAMN04488564_106197"
     CDS             complement(16269..16664)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800804.1"
                     /locus_tag="BM417_RS24075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106197"
                     /product="DUF5313 family protein"
                     /protein_id="WP_093598558.1"
                     /transl_table=11
                     /translation="MNPALKLWYYAGGRLPQRYREFVFEDVTGPKWLMRFTVRSLVQVT
                     PLTTAITLVLVFGLGSAWPLAIACGALGFVVGLYFALSYAPESVDYRLTKYGYPRGSAT
                     QGRRDRHAVRDRERQAKYDAVWRRSEG"
     gene            complement(16661..17110)
                     /locus_tag="BM417_RS24080"
                     /old_locus_tag="SAMN04488564_106198"
     CDS             complement(16661..17110)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946288.1"
                     /locus_tag="BM417_RS24080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106198"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_093598561.1"
                     /transl_table=11
                     /translation="MISTPSIPENPLELERQVCFALAVASRTVIAVYRPILEPLNLTHP
                     QYLVMLALWERSPRTVKDLSNVLQLDPGTLSPLLKRLEAIGYVERQRDKADERALALTL
                     TEAGQELRKEALKIPFKVVEQLDMTFEELAQLNQVLHKVIAKAVR"
     gene            complement(17177..18001)
                     /locus_tag="BM417_RS24085"
                     /old_locus_tag="SAMN04488564_106199"
     CDS             complement(17177..18001)
                     /NRPS_PKS="Domain: Abhydrolase_1 (23-127). E-value:
                     3.1e-17. Score: 54.9. Matches aSDomain:
                     nrpspksdomains_BM417_RS24085_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="BM417_RS24085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106199"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_093598564.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-12, bitscore:
                     43.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 6.4e-16, bitscore: 53.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFVPVAGGDLAVEIHDGDTPPALAIHGVSGSRKLWNWVAAHHFSL
                     IAPDLRGRGDSFEVPGASIRQHADDMVRVLDALDLATVTVCGMSMGAYVAVDLAVRHPD
                     RVRTLVLVDGGFPMPAHAQMTEELLSAAFAPQLAARERTWTVDEYLGVQAVVNPLIDAT
                     DPLIHEYFAHDLTADGHLRLSADTLIADATDVVFGTSRWQELTVPTWFVHAEWSTGPDS
                     PPAYTVEQAQEFRTVLPVLREPVLINEVDHGGTVMTRAGAAVTAEVLAEALK"
     aSDomain        complement(17621..17932)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS24085_Abhydrolase_1.1"
                     /evalue="3.10E-17"
                     /label="BM417_RS24085_Abhydrolase_1.1"
                     /locus_tag="BM417_RS24085"
                     /protein_end="127"
                     /protein_start="23"
                     /score="54.9"
                     /tool="antismash"
                     /translation="AIHGVSGSRKLWNWVAAHHFSLIAPDLRGRGDSFEVPGASIRQHA
                     DDMVRVLDALDLATVTVCGMSMGAYVAVDLAVRHPDRVRTLVLVDGGFPMPAHAQMTEE
                     "
     misc_feature    17959..17973
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.13"
                     /tool="antismash"
     gene            complement(18011..19342)
                     /locus_tag="BM417_RS24090"
                     /old_locus_tag="SAMN04488564_106200"
     CDS             complement(18011..19342)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074580.1"
                     /locus_tag="BM417_RS24090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106200"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_093598567.1"
                     /transl_table=11
                     /translation="MKLPGLITDPNTLAGLSHDEAEWAPAGTPYAAFRPQSTEDVQQAV
                     KACAEHNVPIVPRGAGTGLSGGANATDGCLVLDLSRMDRILEIDRDNLLAVVQPGVVND
                     DLKKAVAAQGLWYPPDPASSPWSTIGGNVATNAGGLCCLKYGVTRDYVLGLEAVLGGPV
                     PYGTAVQLGRRTTKGVAGYDLTSLLVGSEGTLGVVTEITVRLRPAPRPAGTVVGAFDSL
                     VAAGQAVALSTSRGLQPAALELIDRACLQAVEDWKHLGIEPDTEAMLLARAETPEDADG
                     LVAAFTDAGAVWTERSTDSTEAEALFAARRLTYPALERLGPLLTEDVCVPRSAVPAMLA
                     RIEEIGARHQVRIATIAHAGDGNLHPLLITPPGDDNARIAAQAAFEDIIDQALALGGTV
                     TGEHGVGLLKRDGMIRELGPGAHAVQQAIKQTLDPLNLFNPGKA"
     gene            complement(19339..19917)
                     /locus_tag="BM417_RS24095"
                     /old_locus_tag="SAMN04488564_106201"
     CDS             complement(19339..19917)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="BM417_RS24095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106201"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_177320572.1"
                     /transl_table=11
                     /translation="MDTLTTRAAKDLRTRLAIQEAAIVLCLDQGFAATSTKAIADRAGV
                     SERTLFRTFGTKAAIFWYDAFLSRVVRALDPDPDPVAALSKAVRTAIDTITPEQWALEL
                     GRRAVIIKEPDLIATGTQELNTGAAQIATILTPPLASPEQAFDLVLFARFAVAGMGAVP
                     IHAATTPAEWGAELERVAHKAAHGALERS"
     gene            complement(19987..21063)
                     /locus_tag="BM417_RS24100"
                     /old_locus_tag="SAMN04488564_106202"
     CDS             complement(19987..21063)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (22-351). E-value:
                     7.8e-44. Score: 142.2. Matches aSDomain:
                     nrpspksdomains_BM417_RS24100_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682862.1"
                     /locus_tag="BM417_RS24100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_106202"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_218164540.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 6e-43, bitscore:
                     142.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASILFTRGAPSLDIIDQEGLREAAQKAFTDDPGGTFAYGTSVGY
                     VPLRTWLAEQHGVAPEQVLVTNGSMQADAFLFELLVQQGDDVVVEAPTYDRTLLNLRQR
                     GAKIHAIELETDGINVDALEKLLESGVRPKLAHIIPNFHNPAGYTLSEAKRARLLDLAA
                     KYDFVLFEDDPYVKVRFEGEPLPTMLSQDKNEKVVYASSFSKTMAPGIRCGYLVGPKAV
                     IKSIQDIATTTYISPNMVAQSIVNSYCRSGRLEESVVNVRTALRARRDALVAALQRELP
                     EAVFTAPQGGYFMWVELPGVSIDKLVPVAKEHGVEFVKGSDFLLEGGDNALRLAFSGVT
                     PEQIDEGITRLGAAVRAL"
     aSDomain        complement(20011..20997)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS24100_Aminotran_1_2.1"
                     /evalue="7.80E-44"
                     /label="BM417_RS24100_Aminotran_1_2.1"
                     /locus_tag="BM417_RS24100"
                     /protein_end="351"
                     /protein_start="22"
                     /score="142.2"
                     /tool="antismash"
                     /translation="EAAQKAFTDDPGGTFAYGTSVGYVPLRTWLAEQHGVAPEQVLVTN
                     GSMQADAFLFELLVQQGDDVVVEAPTYDRTLLNLRQRGAKIHAIELETDGINVDALEKL
                     LESGVRPKLAHIIPNFHNPAGYTLSEAKRARLLDLAAKYDFVLFEDDPYVKVRFEGEPL
                     PTMLSQDKNEKVVYASSFSKTMAPGIRCGYLVGPKAVIKSIQDIATTTYISPNMVAQSI
                     VNSYCRSGRLEESVVNVRTALRARRDALVAALQRELPEAVFTAPQGGYFMWVELPGVSI
                     DKLVPVAKEHGVEFVKGSDFLLEGGDNALRLAFSGVTPEQIDEGITRL"
ORIGIN
        1 ggtgaagaag tgagctcacc cctggagaac cgatcgagca cggtgctgct gatcggcgcg
       61 tggctgtggg tgggcctgcc gctcgcctac ggcctgtacc ggctcttcct gaacgcggcc
      121 aagctcttcg tctgatgttc aacgcgctcg tcaactggcg caactggcgc ctgccggtga
      181 agctcgccgc ggtgttgatc gttccggtca ccatcgcggt gggctccggc gtactgcaga
      241 tcaattcaca gattgatcgt gccgagtcct acgcggcact ccagcgactg gtgaaggtcc
      301 gcgccgctct gatccccgtg atcgagggcg tgcaggcgga acggcggatc gtcgccgagg
      361 gcgtcggccc gcaactcctc gccgaacagg ccaagcgcac cgacgacgcc cgcgcggcgt
      421 tgcgcgacga gatcgcgaag acctcgctcg gcgaggtcgt gaccgcccgc atgagcgacg
      481 tgcagggcag gatcggcgac ctggcggcgt tgcgcgagcg gaccgacgac gttcccgccg
      541 tgatcaagac ctacagcgag ctcaccgagt cgttgctcga cgtggacgag gtgatcgcca
      601 gcgagttcgg cgacgccgcg ctgctgcgca cggccatggg tctgcaccac gtcgtgcacg
      661 tgcgggacca ggtcctctac cagcaggcgg tcgtgctgtc cgggctcacc cgcggccagc
      721 tgacgaccgc cgaggtgcgg gcgctggtcg agtcgaacgt caagctcggc tacatcgcgg
      781 gcgagttcgc cgcgctcgcg acctcggacc agctcaagac ctacggcaag aacttcaacg
      841 gcccggacat cgaggcccag cgcacgatgc tggccgccgc ggtgctgcac ccgacctcgg
      901 acgcgccgag caccggcaac aacaggccga ggccgttgcc gatcgcggcg gcggactgga
      961 ccaaggcgtc gggcgccgtc gtgacgtcga tggacggcgt ggtgcagggt ctgcagaacg
     1021 acctgcgcga caccgcgaac cgcctgcgcg acgagagcag cgacgcggcc ggaacggcgt
     1081 ccgcgatcct gttcgccagc ctgatcctgg ccggcaccat cgggttcgtc gtcggccgct
     1141 acctgctgcg ctcgctgaac gcgctgcgcc gctccgcgct cgacgtggcg tgggagaagc
     1201 ttcccgagat ggtcgcgacc ggacgcggca gcaccgagat cgagcgcgtg ccggtggaca
     1261 ccaccgagga gttcggccag gtggcgcgcg cgttcgacga ggtgcaccag caggccgtca
     1321 agtcggtcat cgaacaggcc ggcatgcgcg cgaacatgcg caacatcttc gtgaacctct
     1381 cgcggcgcag ccagagcctc gtcgaacgcc agctcaagct gatggaggag ctggagaagt
     1441 acgaggagga cccggaccag ctcgcgaacc tcttcaagct cgaccacctc gccacccgca
     1501 tgcgccgcaa caacgagaac ctgatggtgc tctccggcgg cgacgtggcc cggcggttcc
     1561 acaagccgat cccgctcacc gacgtgctgc gcgcggcggc cgcggagatc gagcagtacc
     1621 agcgggtcat ggtgcacacg gcgcccaacg ccgaggtcgt cggttatgtg gcgagcgacc
     1681 tcgttcgact gctggccgaa cttcttgaca acgcgacggc gttctcgccg ccgcacaccc
     1741 aggtctcgat cagcgcgtcg atcgaggcgg gcgacatcgt gcagatcgac gtggtcgacc
     1801 acggcatcgg catcgacccc gaggcactcg cgggcgtgaa ccagcgcctg gaggccgcag
     1861 gggagggcat ggacgtccag gtgttccgcg aaatgggact tttcgtcgtc ggcaggctcg
     1921 ccgcacgcca ccagatcgtg gtacgtctgg acgccaaaca gggccaaggg actcgcgcga
     1981 tcgtgttggt tccggccgaa ctggcaccaa ggcgggaaga gtcctgggag tctttccgag
     2041 gggagacgat cgaacggcag caggcttcgt ggttccagca gacgacgccg gccgccgcac
     2101 cgccgcctcc ccccgcaccc gcacgtcaga cgccggaatc ggcccggggc ttcctcgacg
     2161 ccttccagcg tggtgtgcag cgcggccttc ccgaccacca ggagagtcga tgagcacgca
     2221 ggtggaccag ttcggctggc tggtcaccaa cttcgccgaa cgcacaccag gcatcgagca
     2281 cgccgtggtg atctcggccg acggcttggt gttgatctcg tcctcgaagc tgcccgaaca
     2341 cgtcgcaccg cagttcgcgg cgatcgtggc gggcgtggtc tcgctggccg actccgcgtc
     2401 gaagtgcttc gccggtgagt cggtcgtgcg caccgtcgtg cagatggacc ggggcgtgat
     2461 gctgttgtcg gcgatcagcg acggctcggt cctcgcggtg ctggcgtcgt cctcggcgga
     2521 cgtcgcgcag atcgcgtacg agatgaccgt ggtcgtgcgg caggtgggcc agctgctcac
     2581 gccggaactg cgggcagagc tggcatgagc agagagcctg acgatcaggt caacttcggt
     2641 gatctgatca gcggtttcag cttcgacagc gaacggatcc gcaagcgcgg caagaagaag
     2701 ggccagcgcg caccggaacc cccgccggag cagccggacc cgtacgccac ggcgccgttc
     2761 gaaccggtcc cgccgctgcc gtcgatcgag gacggcatcg acacgtcgtc gtcgatcgtg
     2821 cgcgcctacg cgtggacggg cggccgcacc acgtccgacg tgcatctgga gatcgagacg
     2881 ctggtctcgg tcaacgagtt ctcggccacc gccgtgcgcc cggagcacca ggacgtgctg
     2941 gccctgtgct cgcagccgcg ttcggtggcg gagatcgccg ccctgcgcgg gctgccgctg
     3001 ggcgtcacca aggtgctgct cggtgacatg gccgggcacg ggctgatcga cgtgcaccgc
     3061 acggcgtcgt cctacggcgg cgaccggccg gacgggatgc tgctcgaacg cgtgctggcg
     3121 ggtctgcgga ggctctagcc ctcggggacg gcccggccgc tgatacggtc gtggctcgac
     3181 tatctggggg tagcgatgga gttccaggac gtggtccgcc gccggcggat ggtgcgcaag
     3241 ttcaccgacg agccggtcag cgaggagagc gttcagcgga tcatgcgcaa cgccgtgcgc
     3301 ggcccgtccg ccgggttctc gcagggccag ggcttcctcg tcctgcaggg ggagccgctg
     3361 aagcggctcg ccgagatgtt cgagtggtgg ggcggggaag aggcgaagac ggccccggtc
     3421 gtcgtcatcc cgttctcgtc caagcaggtc tacctcgacc ggtacgcgca gcccgacaag
     3481 gcctgggccg gtctcaccga ggaacgctgg cccgtgccct actgggacat tgacaccggc
     3541 atggccgcgt tgctgatcct gcagacggcc gtggacgagg ggctgggtgc ggtgttcttc
     3601 ggcacggaga aggagacgtg gccggagttg cgcgcggcgt tcggcgtgcc ggacacgtac
     3661 gtgccgatcg gcatgatcgc gatcgggcac tcggcggagg agggcgtctc cgagggtgcc
     3721 tcgccgctgc ggcgcaagcg caaggcgttc gacgaggtcg tgcactgggg tcagtggacg
     3781 tgagatcgtt cggcctgctc gggccgctgg acgtggtgct cgacgggcgc cacgtccaca
     3841 tcccgcccgg taaacggcgg gtggtgctcg cagccttgtt gctgcgcccc ggtcaggtcg
     3901 tcggggtgga cgagctcgtc gagttggccg gtggctcgcg caacgccctg cagaccaccg
     3961 tcggccggct gcgcgaggtg ttgccggggc tggtgctgac caagccgggc ggatacctgc
     4021 tggacgtgct gcccgacgag gtcgacgtgc accggttcga ccggctggag ccacgcgagg
     4081 cgctggcgct ctggcgcggg cgcccgttcg cggacatcgg cagcgacgca ctcgaacgcg
     4141 accacgtgcc cgcgttgacc gagaagtacc tcgcgacgtt ggaagcgcgg atcgagaccg
     4201 acctgcgcga cggcgagcac gagcggctgg tgcccgaact gcgctcgctc acccgccaga
     4261 acccgaccag ggaacggatg tgggcccagc tgatcgtggc gctgcaccgc tgcgaccggc
     4321 agaccgaggc gttgcaggcc tacgacgaca tccgcggcag gctcgccggg gagctcggcc
     4381 tcgatcccgg caaggacctg cagaaagccc accagcaggt gctcacggcc gacaaccgcc
     4441 cgcgtgcccg caacgacctg cccggcgaca tcgccgactt cgcgggccgc gcctccgacc
     4501 tggacgagat cctcgccgcc gtgccgtccg ggtgcgtcgc gatcaccgcg atcgacggca
     4561 tggcgggcat cggcaagacc acgatcgcgg tccgcgccgc ccaccggctg gccgcccgct
     4621 tccccgacgc gcaactgttc gtggacctgc actcctacac cgcgggcgtc gagccgcgca
     4681 ccccgtccga cgcgctgctg gcgttgctga ccgcactcgg cgtgcccgcg caggacatcc
     4741 cggacggcct ggacgcccgc gccgcccggt ggcgggcgga aatggcgcac cgcaaggcac
     4801 tcgtcgtgct cgacaacgcg ggcagcacct cccaggtccg cccgttgctg cccggcaccg
     4861 gcctggtgct cgtcaccagc agacgccggc tcgtcgacct ggacgccgcg cacacgatct
     4921 cactggacgt gctgtcggaa gcggactccc tgaacctgct cgcgagcatc atcggccgcg
     4981 cgaagctcga ccaggacgtg gactccgcgc gcgagatcgt ccggctctgc ggctacctgc
     5041 ccctggccgt ccggatcgtc ggtgcccgct ggcgcaccag acccgcgtgg tccgcgcagg
     5101 acctgacccg ccgcctcacc gggcaacggc tgagcgagct gaccgcgggc gaacgcagcg
     5161 tcgcggacgc gttcaccctg tcctaccagc aactcacgcc cgagcagcaa cgcctgttcc
     5221 ggcgcctcgg cctgcacacc ggcgaggact tcgacgccta cctggccgcg gcggtcgtcg
     5281 gcacgacgcg ggccgaggcc gaacggctgc tggaagagct cctggacgca catctcgtgc
     5341 agcagaagga gaacggtcgc taccggttcc acgacctcct ggcggaccac gccaaagcca
     5401 gcgtggagga ggacgagagg gtagaggccg tcacccgcgt cctagaccac tacctgcaca
     5461 acgccgccgc ttccgcacag aagatcgcgc ccggccgccc gcagatccat tcggccgcca
     5521 cgtacgtgcc ggtcgaccca cccttgttcg ccacgccggt cgaggcactg gcgtggcagg
     5581 agacggagcg gtcgaacctc agggccgccg tctacctggc cgcgtacgag gggtactacc
     5641 agcacgcttg gcagctgccg caccacttcg cgcacttcct gctcctgcgc ggatccggcc
     5701 gtgaacgagt cgaggtgcag agcgtcgcgc tggcggccgc acgccacctc ggtgacctca
     5761 aggcacgcgc ggaagcgttg cggggcttgg gatcggcgta caaggacgac aacaatccga
     5821 aggcggagga gcacctgcgc gaggcactcg gcctgatgcg gcagatcggc gacctgcgcg
     5881 gtgaggcgtc gacgctgggg ttgctcggca tgatcgcgcg agaacggcgc gagtacgaca
     5941 aggcgatgct gtacttcgaa cgcggtgtcg tgctgatgcg gcatgtgggc gctcagaccg
     6001 gggaagcgaa cgcgctgcac aacatcggca tcgtccacgc cgagcgcgga gagaccggcc
     6061 aggccctcgc gcacctgcag gaggcggtca ccctgctgga agcgcacggc gacgtccggg
     6121 cctccgcgat gacgttgcac gacatggccc acgtgcactt cgacgcgttc aacgacgaag
     6181 agagcctgaa cttctcggag cggtcgctgg ccgcctaccg ggagtccggg gaccggcgtg
     6241 gtgaagcgct cgctctggcc gacttcgcgt actggcggta cgcgatgggc gacctcgccg
     6301 ccgccggcag gacggcgcgt gaggtgggca ggctgtgccg ggcgtacatg atcctgccgg
     6361 acgaccacgc agtgctggcc gcgatggagg acgtgcgcga ccacttcggc caggtcgcgc
     6421 tgctcgtgtc cctgtcgctc gacgcacacg cggcgggccg gttgtccgag gcgctcggcc
     6481 acgtccggcg gtgtctggcc gtggtcaggt cgaccagcca gtggtggagc gagaaccgcc
     6541 tgctcgggca gctctccacc ctgcacttgg cgctcggcga tcgcgacgcc gccgtgcggt
     6601 acggcgagaa ggcggtcacg gccgccgagc agctgggtca acccagggcc gtcgccgtgg
     6661 cgaagcaggc cctcgctaca gcgtcagccc cagcgccacc agcgtgatca cggccgccgc
     6721 cagcacggcg aaggccaccc actgccgcac cctgtcacct gtcgtgcgca tccccggctc
     6781 ccctcggtgg tgttgccacc gagggtcgtg aagcccgtcc ccatctcgtc cccaccgcga
     6841 tcacacggcc ggtgaagccg cgggaattct gtgtgaaact gaattccgac tgacggtctc
     6901 cggcgaaggg agcggtgtgc agaccgcgct gttcccacgc ccccaccagc tccccgcggc
     6961 tgtcgccgac ttcgtggggc gggaggaact gctccagtcc gtcgtcgacc ggatcatccc
     7021 gtttgcgcag gtggtgctgc tgaccggacc ggtcggcacc ggcaagacga cgctcgccgt
     7081 gcacgccgcg caccgggtcg cgaacggtca cttcccggac ggtcagctgt tcgtgcggct
     7141 gcgcggcacg acgccgtacg aggtgctagg ccggttcctc accgcgttcg ggctgcccgc
     7201 tcccggagat ttcgccgccc ggctgagcgc ctatcgagac gctgtcgtgc gccagtcgct
     7261 tctgctggtg ctggacgacg cgacgtgcgt cgaccaggtg aagccgttgc tgccgcacgc
     7321 acctggatgc gcggtgctcg tgacttcccg gcacaccttg aagttgcccc acgtcgtcga
     7381 ggtcggtccg ttggagcccg cgcaggcgat gatgttgctg ggcaaccaga tcggccctga
     7441 ccggctggcc gcccaggacg ccggggaact ggtggccgct tcggactgcc tgccgctcgc
     7501 ggtgcggatc gccggcgcgg tgctcgcggc ccgtccgcac tggcctctcg ccctgctgac
     7561 cgaccggctg cgcgaatcgc ggctggaagc cttgtcgtac ggcggtttgt cggtccgggc
     7621 gaggctggag gagacggcgg gggacctgag cccgcccgcc cgccggctgc tcggtctgct
     7681 cgcggacgtg ggcgcgcggc ggttgccgtc ctgggcgccg gtggcggcgt tcggtgacgt
     7741 gcgcggacag tccgctgtgg acgaactggt gtcggcgcac ctcgtctcgg tcagcgagga
     7801 cggctacgcg gtgccggagc tggtgcggga gttcgcggcg ggccggtccg acgccggcga
     7861 ggccctgcgg cgcgtgctcg gtggctggct gtacctgctg gaccaggccc gcacagcgtt
     7921 gtatggcggc gacttctccg tcatacgcgg ctgttcggca cgcgaggtgg tgcggccgga
     7981 tcgggccctc cgggccgatc cgctggcatg gctggagtcc gaacgggaaa gcctgtgcga
     8041 cgcggtcgac ctggccgccg aggccgacct ggacgaaccg gcctgggaac tggcgcaccg
     8101 gctggtgacg ttcttcgagg cgcgcaccga cttcgaaggc tggcagcaca cgcacgacat
     8161 cgcgctggcg gcgtgcgaga gggcgggcaa ccggcgcggc gcggccgtac tgcactgctc
     8221 gctcgcctcg ttgcacatca gccagagccg ctacgacctc gcgcacgaga tgaccttgcg
     8281 ggccaaggac ttcttcgagg accacgacga tcttgccggc ctcgggctcg tctaccgcaa
     8341 cctcggcatc gtcgcccgct cgtccggcga gctcgccgcc gcccgccgct ggtaccagcg
     8401 cgcgctcgcg gtctacgagc ggttcaccga cccggtcggc gaggcgtccg tgctccagaa
     8461 cctcgcccag atcgacctgt acgacgggga ccccgccggt gcgcgggaac gcctgagcgc
     8521 cgcgctggcc gcgtgcgacg gagccggacc cgcgcgggtc ctggcgcaga tcaactaccg
     8581 cctgggcaag ctgctggccg tggacggacg gcacgacgag gcgttcgacg tgctgaccgt
     8641 cgcgctcgac ctggcccgca ccgcacggga ccggcgcggt gagagcttcg tgctgtacgc
     8701 gttggggcgc aacgagttcg cgcgctgccg gatgggaccg gcgcgcaccc ttctgcgcga
     8761 ggcggcggcc ctttgcgagg cgaacttcga cgtcgtgggc gcggccaggg cacgactgga
     8821 gctgtcccgc gtgcaccagg cctgtggcga ggttcaactc gctgccgagc tggaagcggc
     8881 cgcccgtgcg gtttactcgg aattcggtct gaaaccggtg ctgggcgatt tgatctttca
     8941 gccataaggt tggtgtgagg tattgctcca accgagtgct tggctcgccc gtaagattcc
     9001 gttagggtcg cattcgcgga caattggcag ggcgggcgac gttatcaaaa atcgcccgaa
     9061 aattgatcaa aaattagtca cttgttcgtt tgcaaccatg acgctgctcc gtctgggtgg
     9121 tgccttccac ggcaggacca gccgctgctc accctgcggg acggtgttga cggagacgtg
     9181 tgcgtgcagt ggtgtggggt cggccaaaag gggcttgcga gtcgtgagaa tcggaccagt
     9241 cttgtctaat ggcatcgccg gtatccgtcc ggcggacagt ggcctcgaca cgggggtgga
     9301 acgcaccatg ggtggtgtcc ctacgtttcc ccacggcaga ccactgacgt gggcggacct
     9361 ggaggcgatg cctgatgacg ggcaccgttt cgaactcgtc gacggggtgc tcgtcatgag
     9421 cccctcaccc cgccccgtgc accagcgggt agtcgcccga ctgctggtgg cgctgaccgc
     9481 tgtctgccca ccggagctgg aggtccttcc cgctccggtc gacgtcgtgc tcgccgacga
     9541 cacggtcttc atccccgacc tggtggtggg ccgccgcgag cagttctcga aacaggcgct
     9601 catcgggccg ccggtgctgg cggtcgaggt cctgtcgccg cgcacgcgac acgtggacct
     9661 cgaactcaag cgcgcgaagt tccaggaagt cggctgcgag aactactgga tgatcgacta
     9721 cgacagtccg tggctgcggt gcctgcacct ggagaacggc gtctacgtcg aacaggcgag
     9781 gtccgacggc gaagagatca tcgagttgca gttcccgttc gcggtgaaac tgagcgccca
     9841 gtcactggtg cgctgagtgt tcgccggtcg aaaccgactg ggctgaacgg gcgacaccga
     9901 tctacgaacg tgtggatcaa cgtttcacca tctggcgtcc ccgcgcgtcg ggctggttgc
     9961 gtgcatcgcg acacgtccac cgcgcggagg tccaacgcac atgcagccgt tccagctgcc
    10021 ggagttctac acgcctcatc cggccaggct gaacccgaac ctcgaacgcg cccgcgtcca
    10081 cacacgtgcc tgggcgcacg agatggacat gatcgacgtg ccgcagcacg gaacggtgat
    10141 ctggaccgac gacgacctcg agtcccacga ctacgcgttg ctctgcgcgt acacccaccc
    10201 cgactgcgac ggtgagacgc tcgacctcgt caccgactgg tacgtgtggg tcttctactt
    10261 cgacgaccac ttcgtcgagc tctacaagcg caacccggac atcaagggcg cgcaggccta
    10321 cctcgaccgg ctgccgctgt tcatgccggt caacggcgtg atcaccgaga cgccgacgaa
    10381 cccggtcgag aagggcctcg cggacctctg gcgccgcacg gtcgccaagc actcgctcga
    10441 ctggcgcgag cggttcgcct ccaacaccaa gcacctgctc gacgagtcga tgtgggagct
    10501 gcacaacatc agtgcccagc ggctcagcaa ccccatcgag tacatcgaga tgcgccgcaa
    10561 ggtcggtgga gcgccgtgga gcgcgaacct ggtcgagcac gcggtcggcc tcgaggtgcc
    10621 ggcgcccatc gccctgtcca ggcccatcgg ggtcctcagg gacacgttca gcgacgccgt
    10681 gcacctgcgc aacgacctgt tctcctacga gcgcgaggtg ctcgacgagg gcgagctgtc
    10741 caacagcgtg ctggtgttcg agaagttcct cgacatcccc acccaggacg ccgcggaggc
    10801 cgtcaacgac ctgctgacgt cccggctgca ccagttcgag cacacggcgc tcacggaggt
    10861 gccgatcctg ctggacgagc acgccatcga ccccatcggg cgcgcggccg tcctgggcta
    10921 cgtgaagggc ctgcaggact ggcaggcggg cggccacgag tggcacctgc ggtcgtcgcg
    10981 gtacatgaac aagggggcca agacgggtct ctcggccacg aacatcctcg gctcgtacgc
    11041 caagaccatg ccgcaacgac tcaagcagtt cagcagcaca ccgaaggtcg tcgagccgta
    11101 cacgctgccg gagttcaaga cgcccttcac gctgaccctg tcgccgcacc tcgaccaggc
    11161 gcgcgaggag gtcatcacgt ggggccggga gatgggcatc cacgacgagg gcatctggga
    11221 cgaggccaag caccggggat tcgacctcgc gctgtgctcg tcggggctcg atccggacgc
    11281 gacgccggag gagctgttcc tctcggcggc ctggctcacc tggggcacct acgccgacga
    11341 cgtctacccg tgggtgttcg ggcggctgcg ggacctggcc gggttgaaga tccagaccgc
    11401 gcggctcaag cagtgcatgc cgctggacat ggtgctgacc gtggcgccgg tcaacgcgat
    11461 ggaacgcggc ctggccgacc tgtggcagaa gaccgccggt cccatgtccg gcgagttcgg
    11521 cgcgacgttc cggcagaccg tggacgacat ggtggacgcg tgggtgtggg aggtggtcaa
    11581 catccagcag aaccgcgtgc cagacccggt cgactacctg gagatgcggc ggtcgacgtt
    11641 cggttccgag ctgacgacgt ccttgtcgcg cttttcgcat tcgacgacgg tgccgccgga
    11701 gatctgggga accagggtca tccagaccat ggagcggtcg gccatggatt actgctgcct
    11761 gctcaacgac gtcttctcgt acttgaagga gattcagtac gagggcgaag tgcacaacat
    11821 ggtgaaggtg atcgagaact tcctcggcgt ttcccagtcc cgcgcgttcg aactgaccta
    11881 cgcgttgatg gacgcccgcc tcgggcagtt catcgcctcg gtcgacacgc acctgccgaa
    11941 gatgttcgac gacctctcac tggactcggc cacgcgcgcg tcgctgaccc ggtacgccga
    12001 cgagctgaag gactggatcg tcgcgatcat caactggcac aagggaacca gccggtacgg
    12061 cgaggacgag atccggaccc cggtgaactc gggagcgttc agccaaggcc cgtcgggcat
    12121 cggtacgtcg gccgcccggc tcctcgcccg gtagtcgctg tcaggcgctg accgccgacg
    12181 gtcagtggac ggtcagcgcc tgcccgcacc ttgtgagcaa caccgactca cagggggcaa
    12241 caccatgaag aacgtcctga tctccggcgc cagcatcggc ggacccgcgc tcgcctactg
    12301 gctgcgccgc aacggtttca gcgtcaccgt ggtggagcgg tcgcgcggca tgcggcccgg
    12361 cgggcaggcc atcgacgtgc gcggcccggc gctggaggtc atcgagcgca tggggctcgg
    12421 cgaccagttg cggtcgttca gcaccaacat gcgcggcatg aacgtggtcg acgcagacgg
    12481 caacgagctg ttccgctcca ccacgcacac cctgagcggc ggcgacctgt cgagccccga
    12541 cgtggaactc ctgcgcgacg acctcgcccg gatgctcttc gacgcggcgg acggcgtcga
    12601 gtacctgttc gacgacacga tcacctcgat cgacggcacc cgcgtcacgt tcgagaaggc
    12661 ggcaccgcgc gacttcgacg tcatcgtcgg cgcggacggc ctgcactcca acgtccgcag
    12721 gctcgtgttc ggacccgagt cggagttcat cacccacctc ggcatgaacc tcgccgtctt
    12781 caccgcgccg aacttcctcg ggctcgacca ctggcagacg ttccagcagg gcgaggtcgt
    12841 cggcggcggc atcatgagcg cccggtcgaa cgcggaatgc cgtgtctaca tgggtttcaa
    12901 cggcgtgacc gacttcgacc accgcgacgt cgacgctcag cgcaccctga tcgcggagaa
    12961 gttcgccgac gccggctggg cgtggccgac cgcgctcaag cacatgtggg aggcgccgga
    13021 cttccacttc gactcgatga gccagatccg gatggactcc tggtcacgcg gcaacgtcgt
    13081 gctgctcggc gacgccggct actgcggttc gccgttgtcc gggcagggca ccagcatggc
    13141 cctggtcggc gcgtacgtgc tcgccggtga gctcgccaag gacccgtcga ccgccttcca
    13201 gcgctacgag gagatcctgc ggccgtacgt gatcgccaac caggacatgg cgttgaagaa
    13261 ccaggcgaac ggcggcgcgc ccaccgagga gttcacggac gtcgtcaaca gcctcaccct
    13321 tccggcctac tgagcacgtc tcgagcaaag aattggctca gaccattgac gacaaaaggg
    13381 atgtttgagc aggctgaagg cagggccgcc gcccccgact cgtgaggagg agccgtgaga
    13441 actcgcgctc tcgccgcggt catcgctgtc acggcagcgt tgtccgtcag tgcgcagtcg
    13501 caagccgcgg aaccactgca gagcctggtg ccggtcccgg tgtcggtgca ggccagaagc
    13561 ggtgtcacgc acaccctgac ggcagccacg aagatctaca cagcccctgc cgcgcgcgac
    13621 gtcggcacct tcctcgccgg agtcctgcgg ccctcgaccg gctacgccct gccggtgtcc
    13681 gacgcgacag gaaccccggc ggacggaatc tcgctgctgc tctcgggcgc gccgggcacg
    13741 gtcggcgacc agggctacca gctcgacgtc gcggcgaact ccatcgtctt gcgcgccaac
    13801 acgtccgagg gtctcttcac gggcgtgcag acgctgcggc aactgttgcc cgccaaggtg
    13861 gagagcacga ccgcgcaaac cggtccgtgg accgtgccgg gcacggtgat cgtcgactac
    13921 ccgcggttct cctaccgcgg cgcgatgctc gacgtggccc gtcacttcca cccggtctcg
    13981 acggtcaagc gctacatcga ccagctggcg ctctacaaga tcaattattt ccacctgcac
    14041 ctgagtgacg accagggctg gcggatcgtg gtcgacagct ggccgcgcct cgcgacgtac
    14101 ggcggcagca cgcaggtcgg cggcggcccc ggcggttact acaccaaggc gcagtacagc
    14161 gagatcgtgc agtacgcggc gtcgcgcaag atcacggtga tccccgagat cgacatgccg
    14221 ggccacacca acgccgcgca ggcctcgtac gcggagctca actgcaacgg ccaggctccg
    14281 ccgctgcgca cggacatcga ggtcggctat tcctcgttgt gcgtcaacaa ggagatcacc
    14341 taccagttcg tcgaggacgt ggtgcgcgag atcgcggcgc tcacgcccgg cccgtacttc
    14401 cacatcggcg gcgacgaggc ccacgcgacg tcggacgccg actaccagac gttcatgaac
    14461 cgcgccctgc cgatcgtgaa gaagtacggc aagaccgtgc tcggctggca cgagttcgtg
    14521 aagaccacga ccgacaccac ggccatcccg cagtactggg gcacctcgac gtccaacgcg
    14581 acggtgcagg cggcggtggc gcgcggcaac aaggtcatca tgtcgcccgc gaacaaggcg
    14641 tacctggaca tgaagtacaa ctccagcacg cctctgggcc tgtcgtgggc cggtctgatc
    14701 gaggtgcaga ccgcctacga gtggaacccg ggaacgcacc tgagcggtgt cccggagtcc
    14761 gcggtccgcg gcgtcgaggc tccactgtgg acagagacgc tggtgaccgg gcgcgacatc
    14821 gagttcatgg cgttcccgag gctcggcgcg atcgccgaac tggcctggtc gccgtggtcg
    14881 acgcacaact gggaccagtt caaggtgcgc ctgggcaacc agggcccgcg ctggacgacc
    14941 atgggcatca acttctacag gtcgacccag gtgccgtggg acaccggcgg cccggggccc
    15001 ggcccgtgca cgcagccggc gtgggagcgc gacaaggtct acaccggcgg caacgtggtc
    15061 tcgcacaacg gccacaagtg gaccgcgcag tggtggacgc ggggtgagga accaggcacc
    15121 accgggcagt ggggagtctg gcgcgacggc ggcgtctgct gattgagttg tgagggccgc
    15181 gggactcttc ccgcggccct caccacgttc cacgggggtc ctgatgcgcg tgctggtcac
    15241 caacgacgac ggcatcgact cgccggggct ctacgcgctg gcccgcgcgg cctcgtcgct
    15301 cggctgggag gtgctggtcg ccgcgccctc gacggaggcg agcggaaccg gtaccagcct
    15361 cgcctcggcc tccgggcgga gcaggatccc gctcgaacga cggcaggtcg acgggttcga
    15421 ggcgttcgcc gttcctggac atcccgcgct gatctcgttc atcgcctgcc agggcggctt
    15481 cggcgagcgg ccggacctgg tgctgtccgg tgtgaacctc ggcgcgaaca ccagcaccgg
    15541 catcctgcac tccggcacgg tcggcgccgc gctggccgcg agcgcgcggg gagtctcggc
    15601 cctggcggtg tcgctggacg tggaatggga cggctccgcg cccttgtggg acacggcgac
    15661 cgacgtcgcg cgggcggtgc tgccgatgct cgcggagatg ccggccgcga ccgtgctcaa
    15721 cctcaacgtg ccgaacgccg ccacggtccg gggaatcgaa tgggcggaca tcgcgccgtc
    15781 gagcccctac caggtgcact tcgagtcgaa cggcgacgag ctgaagctgc gggccgtcaa
    15841 aaccgatctg gaacccgtgc cgggcaccga gatcgcgttc ctggcggacg gttacgcggc
    15901 gttgacgccg ttgcgctcgg tggccgccgc ctctacgtcc ggtctgcctt cgccggcctg
    15961 gccagcgtga tcaccagccc gatcagggcc gtccgcacct cgagaaaact ttcggtcgtc
    16021 acgtcgttga gcgagaaggc cagcgtcccg aacgacacca gcaggaggat tccgtacatc
    16081 cgcgcgaggt cgtgccgcca cgccatcgcg acgcccagcg ccccgacccc gatctggatc
    16141 acgtggtagt tcgggtccaa tccgaacacg tcgaaccaac cgaacgcgag ctgtaacaag
    16201 cctgccgtga gagtgagcgc ctgcggcctc gtgaactcga actgatcgct caacaaggcc
    16261 ataggtctct acccttcgga ccgccgccag accgcgtcgt acttcgcttg tcgttcgcgg
    16321 tcccgcacag cgtgtcgatc ccggcgaccc tgagtcgccg aaccccgtgg atacccgtac
    16381 ttcgtgagcc ggtaatccac gctttcgggt gcataggaga gcgcgaagta cagtcctaca
    16441 acgaaaccga gcgctccgca cgcaattgcg agtggccacg ccgagccgag tccgaagacc
    16501 agcaccagcg tgatggccgt cgtcagcggc gtgacctgca caaggctgcg caccgtgaag
    16561 cgcatcaacc acttcggacc ggtcacgtcc tcgaagacga actcccggta cctctgcggc
    16621 agcctgccgc ccgcgtagta ccagagcttc agcgcggggt tcatcggacg gccttggcga
    16681 tcaccttgtg cagcacctgg ttcagctgcg cgagctcttc gaacgtcatg tcgagctgct
    16741 ccacgacctt gaaggggatc ttcagcgctt cttttctcag ttcctgcccg gcctcggtca
    16801 gggtgagcgc gagcgcgcgc tcgtcggcct tgtcccgctg ccgctcgacg tacccgatcg
    16861 cctcgagccg cttgagcagt gggctgaggg tgccggggtc gagctgaagg acgttgctca
    16921 ggtccttgac ggtgcgcggc gaccgctccc agagcgccag catcaccagg tactggggat
    16981 gcgtgaggtt cagcggctcc aggatcgggc ggtagaccgc gatgaccgtc cggctggcca
    17041 cggccagcgc gaagcagacc tgccgctcga gttcgagcgg gttctccggg atacttggtg
    17101 tactaatcat tggtgtacac actaactcgg aggcgcgctg agatccaaga ggtgtggcgc
    17161 agtgctcaga cgtggactac ttcagggctt cggcgaggac ctcggcggtg acggcggcgc
    17221 ccgcgcgggt catcacggtg ccgccgtggt cgacctcgtt gatcagcacg ggttcgcgca
    17281 gaacgggcag cacggtgcgg aactcctgcg cctgctcgac ggtgtaggcg ggcgggctgt
    17341 ccgggccggt gctccactcg gcgtgcacga accaggtcgg cacggtcagt tcctgccagc
    17401 gcgacgtgcc gaagacgacg tcggtcgcgt cggcgatcag ggtgtcggca gacagcctca
    17461 ggtggccgtc ggcggtcagg tcgtgggcga agtactcgtg gatcaacggg tcggtcgcgt
    17521 cgatcagcgg gttcaccacg gcctggacgc cgaggtactc gtcgacggtc caggtgcgtt
    17581 cgcgggcggc cagttgcggg gcgaacgcgg ctgagagcag ttcctcggtc atctgggcgt
    17641 gggcgggcat ggggaagccg ccgtccacga gcacgagggt gcgcacgcgg tccgggtggc
    17701 gcacggccag gtcgacggcc acgtacgcgc ccatcgacat gccgcacacg gtgacggttg
    17761 cgaggtccag ggcgtcgagc acgcggacca tgtcgtcggc gtgctgcctg atggacgcgc
    17821 cggggacctc gaagctgtcg ccgcggccgc gcaggtccgg tgcgatgagg gagaagtggt
    17881 gcgccgccac ccagttccac agcttgcggc tgccgctgac gccgtggatc gccagcgcgg
    17941 gcggggtgtc gccgtcgtgg atctcgacgg ccaggtcgcc accggctacc ggaacgaaca
    18001 tgcggactcc ttaggccttg ccgggattga agaggttcag cgggtcgagc gtctgcttga
    18061 tcgcctgctg cacggcgtgg gcgccggggc cgagttcgcg gatcatgccg tcgcgcttga
    18121 gcaggccgac gccgtgctca ccggtgacgg tgccgccgag ggccagtgcc tggtcgatga
    18181 tgtcctcgaa cgccgcctgc gccgcgatcc gggcgttgtc gtcgccgggc ggggtgatca
    18241 gcaacgggtg caggttgccg tcgccggcgt gcgcgatggt cgcgatccgg acctggtggc
    18301 gcgcgccgat ctcctcgatg cgcgcgagca tcgcggggac cgcggaccgg ggcacgcaca
    18361 cgtcctcggt gagcagcggg ccgaggcgtt cgagtgccgg gtaggtgagg cggcgggcgg
    18421 cgaagagggc ctcggcctcg gtcgagtcgg tggaccgctc cgtccagacg gcgcccgcgt
    18481 cggtgaaggc cgcgaccagg ccgtcggcgt cctcgggcgt ttcggcgcga gccaggagca
    18541 tggcctcggt gtccggctcg atgcccaggt gcttccagtc ctcgacggcc tgcaggcacg
    18601 cgcggtcgat cagctccagc gcggcgggtt gcaggcctcg gctggtgctc agcgcaacgg
    18661 cctgacctgc ggcgacgagg ctgtcgaacg cgccgacgac ggtgccggcg gggcgcgggg
    18721 ccgggcggag gcggacggtg atctcggtga cgacgccgag cgtgccctcg gaaccgacga
    18781 gcaggctggt caggtcgtag ccggcgacgc ccttcgtggt gcgcctgccc agttgcaccg
    18841 cggtgccgta ggggacaggg ccgcccagca cggcctccag gccgagcacg tagtcgcgcg
    18901 tcacgccgta cttgaggcag cacaggccgc ccgcgttcgt ggcgacgttg ccgccgatcg
    18961 tcgaccacgg tgagctggcc gggtccggcg ggtaccagag tccttgcgcg gcaacggctt
    19021 tcttgaggtc gtcgttgacg acgcccggct gcaccacggc gagcaggttg tcccggtcga
    19081 tctcgaggat ccggtccatc cggctcaggt cgaggaccag gcagccgtcc gtcgcgttgg
    19141 cgccgccgga caggcccgtg cccgcacctc gcggcacgat cgggacgttg tgctcggcgc
    19201 aggctttcac ggcctgctga acgtcctcag tggactgcgg ccggaacgcc gcgtacggcg
    19261 tgcccgccgg agcccactcg gcctcgtcgt gactgaggcc ggccagcgtg ttcgggtcgg
    19321 tgatgagtcc gggcagcttc atgaccgctc caacgcgccg tgcgcggctt tgtgcgcgac
    19381 tcgttccagt tccgcgcccc attcggcggg cgtggtggcg gcgtggatcg ggaccgcgcc
    19441 catgcccgcc actgcgaacc gggcgaagag caccaggtcg aaggcctgtt cgggggacgc
    19501 gagcggggga gtcaggatcg tcgcgatctg cgcggcaccg gtgttgagct cctgcgtgcc
    19561 ggtcgcgatg aggtccggtt ccttgatgat caccgcgcgg cggccgagtt ccagcgccca
    19621 ctgctcgggg gtgatcgtgt cgatggccgt gcgcacggct ttgctcagtg ccgcgacggg
    19681 atccgggtcg ggatcgaggg cgcggacgac ccggctgagg aacgcgtcgt accagaagat
    19741 cgcggccttg gtgccgaacg tgcggaacag cgtgcgttcg gagacgcccg cgcggtcggc
    19801 gatcgccttg gtcgacgtgg cggcgaagcc ctggtcgagg cacaggacga tggccgcctc
    19861 ctggatcgcg aggcgggtgc gcaggtcctt cgcggcgcgc gtggtcaagg tgtccacggc
    19921 gccacggtag cgcgaagtgt cagttactgc cagaagttct ggcagtaact gacactttcg
    19981 agacgctcag agcgcgcgga cggccgcgcc gaggcgggtg atgccctcgt cgatctgctc
    20041 cggcgtgacg cccgagaacg cgaggcggag ggcgttgtcg ccgccctcca gcaggaagtc
    20101 cgagcccttc acgaactcga cgccgtgctc cttcgcgacc ggcaccagct tgtcgatcga
    20161 cacgcccggc agctcgaccc acatgaagta gccgccctgc ggcgcggtga agacggcttc
    20221 cggcagctcg cgctgaagcg ccgctacgag ggcgtccctg cgggcgcgca gcgcggtgcg
    20281 gacgttcacg accgactcct cgagacggcc ggagcggcag tacgagttca cgatcgactg
    20341 cgccaccatg ttcggcgaga tgtacgtggt ggtggcgatg tcctggatgc tcttgatgac
    20401 ggccttcggg cccaccaggt aaccgcagcg gatgccgggc gccatggtct tcgagaacga
    20461 cgacgcgtag acgaccttct cgttcttgtc ctgcgacagc atcgtcggca gcggctcgcc
    20521 ctcgaaccgc accttgacgt acgggtcgtc ctcgaacagc acgaagtcgt acttggccgc
    20581 gaggtcgagc agacgcgcgc gcttcgcctc ggacagcgtg tagccggccg ggttgtggaa
    20641 gttcgggatg atgtgcgcga gcttcgggcg cacaccgctc tccagcagct tctcgagcgc
    20701 gtcgacgttg atgccgtcgg tctccagctc gatcgcgtgg atcttggcgc cgcgctggcg
    20761 caggttcagc agcgtgcggt cgtaggtcgg cgcctcgacc accacgtcgt cgccctgctg
    20821 gacgagcagc tcgaacagga acgcgtcggc ctgcatcgag ccgttggtga cgagcacctg
    20881 ctccggcgcg acaccgtgct gctccgcgag ccaggtgcgc agcggtacgt agccgacgct
    20941 cgtgccgtac gcgaaggtgc cgccggggtc gtccgtgaag gctttctgcg ctgcttcgcg
    21001 cagaccttcc tggtcgatga tgtcgagaga gggcgctccg cgcgtgaaca ggatcgaggc
    21061 catgcgcgga gcgtacaact cccacaatct gggctacggc ctatatacgt atgagttgag
    21121 caggctcacc gctgcctgcg cgctgcccag gtgataaaga tcgactgcca ggaagttcgg
    21181 cttcttgcgc gccgcgggct ggcagaactg ctgtgcccgg ttcgcgagct tgccgttgtc
    21241 cgtcgtggcc gtgctcgtga acggaacgtc ccggaagtgg ttcatcacga acaaaggctg
    21301 gaagctgccc gtcgcggtga gcggtttttc atcccatcgg ctgtaacagg accagtcgga
    21361 actgcccagg cccgaaccca tcgaccagta gttctcgacc gtccagtcct tctggtagag
    21421 cacgccgctg tcctcgcgcc cgtccttgcc gtggtcggtg aagatgatca gccgcttgtt
    21481 gctgctccgc agctggctgc gggtgggcca cccgttctgc tgcacgcctt ccgcccggta
    21541 caggacgtcg ttcagcccct gcaccttgcg gagttcggcg cgcaacgtgt tcgcgtcgac
    21601 gtagtcctcc aggaagaccg tgatgatctc gccgcggttg ttcttgagga agtccacgat
    21661 ccgctggatg tcgacgttga gcgcgaccgg cttgctcacg agcgtgcagc tgttgtggca
    21721 gaggatcgcg ccgtccggcg tctggtgaat gtccagcatg aagccccgga cgccatcgcc
    21781 cagctgctgc acgatgccgc gcgtctggtt cttcgcgagg ttgacgaacg gcggcgcgaa
    21841 cccgccgtcc acgccgttcg cataggcgtt gtgggcggtc aggaacgtca tctggtcgag
    21901 ccgcggatcc gccggcatcg gctcggtcgg actgctgacc ggcgtcagat accagcgcga
    21961 ctcaccgccg agactgaaga attcccattg atcaccgaac tgacggggct cgtgaaccgt
    22021 atccccttgt gaacacgaac ccatggtgag ctgacgggtg atgcactgac ccggcgagtc
    22081 ggtgttctcg aacctcccgt cgctcagccg ccactgctgg cggtcctcgt tgcctttggg
    22141 gcggtgcagt gcca
//
