LOCUS       NZ_FOYL01000001        22607 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Lentzea waywayandensis strain DSM 44232, whole genome shotgun
            sequence.
ACCESSION   NZ_FOYL01000001
VERSION     NZ_FOYL01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lentzea waywayandensis
  ORGANISM  Lentzea waywayandensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Lentzea.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900115955.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:54:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,449
            CDSs (total)                      :: 9,363
            Genes (coding)                    :: 9,244
            CDSs (with protein)               :: 9,244
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 26 of 119
            Pseudo Genes (incomplete)         :: 101 of 119
            Pseudo Genes (internal stop)      :: 5 of 119
            Pseudo Genes (multiple problems)  :: 12 of 119
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:39:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 674460
            Orig. end                         :: 697067
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOYL01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22607
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22607
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22607
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12607](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12607
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(64..78)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.41"
                     /tool="antismash"
     gene            complement(171..1964)
                     /locus_tag="BM417_RS03170"
                     /old_locus_tag="SAMN04488564_101639"
     CDS             complement(171..1964)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.5"
                     /locus_tag="BM417_RS03170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101639"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_218164303.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.2e-51, bitscore:
                     170.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGLRRTSLCAAAVSAAVFSVVSPVNAAPSQIQSQPDSTQVNRPF
                     ERLIVGYKPGTAEASSDTAASDDARKKGKSVHRRTASGAVVVDLGAKTTNADSTIQAFK
                     SDPKVAYVEPDLLMQPFADPNDTEYSRQWDLFEATAGMNVPGAWSSSTGTGVTVAVIDT
                     GYVAHSDLASKVVAGYDFVSDSARARDNNGRDSNPADEGDWTARGECGTDANGQPVPAA
                     DQGSSWHGTHVAGTIAASTNNSKGIAGIAYDAKIQPLRVLAKCGGATSDIADAITWASG
                     GTVSGVPANTNVAKVINMSLGGQSSCSTTYQNAINGAINRGTTVVVAAGNSNANVANFT
                     PANCNGVITVAATGREGNKAFYSNFGTRIDIAAPGGETRRGTDTPGTITTPENGIWSTL
                     NAGTTTPGAENYKPYQGTSMAAPHIAGLAALLVAKKPSLTPAQVKDLIKTNSRPLPGTC
                     SGGCGAGLADATKAVNAVDTTPPPSGGLENTTDVAIPDRGTAVTSSITSTVTGNASSAT
                     KVGVDIVHTYRGDLVIDLIAPDGTAYRLKNSSSSDSAGNVVATYTVNASSEVAAGTWKL
                     RVQDVYSGDTGYINSWNLTLQ"
     misc_feature    2043..2058
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.05"
                     /tool="antismash"
     gene            2147..3073
                     /locus_tag="BM417_RS03175"
                     /old_locus_tag="SAMN04488564_101640"
     CDS             2147..3073
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="BM417_RS03175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101640"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_143138476.1"
                     /transl_table=11
                     /translation="MLGHLGVNAEQTAVYELLVTGGSRTTDEIGASSALLESMRELGMV
                     RHLPGDVWQAVPPDLAVEALIAAREEANRRARADVGPLMELYLRNRDEELADNAFVEVV
                     SGKDAVRDLWRTLLGGAREEVCVLDQPPYLSPQEEHAELEDSTRQRDVQWRVVYDRSAV
                     DLPGRVTEIIELVAAGERARVTPTLPFKLAVIDAHAAVLPVASGDVIDKVLLIRPSALL
                     DVLRSTFELYWDKGIPFSPGGIYAAAADVDPNLLGLLAAGLTDESIARQLGLAPRTVQR
                     RVRQLMDRCGAQTRFQAGVQAMRRGWL"
     gene            3146..3721
                     /locus_tag="BM417_RS03180"
                     /old_locus_tag="SAMN04488564_101641"
     CDS             3146..3721
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS03180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_101641"
                     /product="hypothetical protein"
                     /protein_id="WP_143138477.1"
                     /transl_table=11
                     /translation="MRMRKVMAAALTGLALIGLAGTASASGSGDLVWPPKDVTPVHKTK
                     AELEKQAAGFTARQRQTFPKVFHGAQNVAPGNWGGEAEGLFDDMQYLTNWTEFTVGDQG
                     RTVFMQVNAPGFFRESPAQLCERDKCTGRTSDHRGGVTVFTKNDLHGITVAWNFRRNGE
                     VVWAQSWTPGTEAQLAAVASDRAYTFTR"
     gene            complement(3776..5653)
                     /locus_tag="BM417_RS03185"
                     /old_locus_tag="SAMN04488564_101642"
     CDS             complement(3776..5653)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015531.5"
                     /locus_tag="BM417_RS03185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101642"
                     /product="S41 family peptidase"
                     /protein_id="WP_093588186.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 1.8e-12, bitscore:
                     43.1, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAHPNVANSVGLAEFLATAGTLTLAQRKLIVDQALILLEQNY
                     AHLPLKVAMHAVNPVQRLRVLRARLERQTDATAEAEWQFHRELSSTFHSVRDLHTNYLL
                     PAPFAGKIAFLPFQLERCFAADGTEQYLVARTVANFNGLAVGAEVTHWNGTPIARAVAL
                     NGAVFAGSNAAANHARGLESLTLRPLVIQLPPDEDWVVVTYRDETGAAADIRVDWQVTE
                     NLPPMTDVDSLSPAAAAQGVDLDSDEKARAKKLLHAPKVVQAEAAGGAVAMAAQDVATT
                     MPGVFRARPITTPSGTFGHLRIFTFSVDDPDAFLAEFVRLANLLPQNGLIVDVRDNGGG
                     HIFASEFLLQTMTPRPVQPEPVQFLSTPLNLRISRRHAENPTGQIDLGPWFPSLDSSTE
                     TGQAFSCSHTITPVEGANAVGQTYHGPVLLITDARCYSATDIFAAGWADHDLGPILGVD
                     DNTGAGGANVWTHGLLMTLLKIPAPGDGESPYKSLPNRANMRVSIRRTLRVGKLAGTPV
                     EDLGVRPTHQHKVTRADLLQGNVDLLARAGSLLAALPVRRLGVAVEGTTVSLDTVNLDR
                     VDIYVDGRPATSLDVTDGAHTATLTATGREVRVEGFADGQLVAARKVAS"
     gene            5774..8113
                     /locus_tag="BM417_RS03190"
                     /old_locus_tag="SAMN04488564_101643"
     CDS             5774..8113
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS03190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_101643"
                     /product="hypothetical protein"
                     /protein_id="WP_093588187.1"
                     /transl_table=11
                     /translation="MKPRVLELRIHGVNNTPPDAMLALPEHAVEQFRGDRFGSFWRPKP
                     DKLAELPAEHPGQVPAAVRREAYSWGGMARSSPGVPGSGVPSVLANALGRVGWALLLPF
                     GLANVAYWSRKLPDDSTPTTRHMVWWNAGRGAASTRLFGLGLTVLLVLAVCEVAIDVYA
                     IQCSLPGTTCKRLPDFLDVLGDPARHVRVLAASVVPVLLLLGLVALTSLSRSRYEQATM
                     RRRPVRRPGVMLSRASMWEGSPRIRRLTRLHISAGCCVVVLVTSAQLWRHAFFLVLTVL
                     AAGVLAVVMARVVVTATDCPDVPSTEKGGLWSWLLMISAVLVLVAHGFGLYAIEPAFDG
                     PLWLTSWGPPVVTVALLGSVLAAWSWRRNDAKGPLVMLVLFVAFMVATYWVPLAWIGAV
                     VFGGALAWRARPRAGDQWQAWRGAGPGVLLGLSLTSSVTLATVLVLTFRGWIGTGLQAP
                     PFYSWFSAAFAVALVPLVLLVLAQAVVLLSRLTKPAVLDDEAEVLVVRVRHVVAVTHRA
                     ENVAGVLSTLGVLALVLTCYLAFASPAWSQWSGVTWVVGKGDWVTGLAGVAVIGSFVGA
                     GMLTNRRPLGLVWDLMCFLPRTAHPFAPPCYAERAVPEIADRTREFLDESPDHRVVLSA
                     HSLGAVLAVAALFALPEGYLERVRLLTYGVQLRPYFGRIFPELLGPSVLGTPDVRAGAM
                     FSCDPWRRNPGDTPERGLTTLMGKNWINLWRRTDYLGFPVHGWEPNDLDRRAGETNGSP
                     DKVETHGDYHLCAAYRDALTELARPI"
     gene            8180..8770
                     /locus_tag="BM417_RS03195"
                     /old_locus_tag="SAMN04488564_101644"
     CDS             8180..8770
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672680.1"
                     /locus_tag="BM417_RS03195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101644"
                     /product="superoxide dismutase family protein"
                     /protein_id="WP_093588188.1"
                     /transl_table=11
                     /translation="MRTTVATLVGAVLLTGGLAACSSEPAPSSAPQTQAVKPVAETDVA
                     APAASGDQPKGITYDVARIPLGAKLSTGSSVANGRTTVELKVSGLLPNTKYGSHVHTKP
                     CGAKPADSGPHYQNEKDPVSPSVDSKYANAQNEIWLDFTTDAQGAATGTATVSWEFRKG
                     EANAVIVHATHSSTEHGKAGTAGDRLACLTAAF"
     gene            complement(8767..9858)
                     /locus_tag="BM417_RS03200"
                     /old_locus_tag="SAMN04488564_101645"
     CDS             complement(8767..9858)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="BM417_RS03200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101645"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_093588575.1"
                     /transl_table=11
                     /translation="MREFGELLRTHRIGAGLTQQQLADFAMVSVRAIRDLECGRTRSPR
                     AETVRLLADGLRLDDGSRADLQQAGGRSAGRTAVAPPAPAGPAGMIVGREAEAAALAAL
                     LTEGRPEAGGYESRRLVTVTGVSGVGKTRLALEVAGELHFRHGWSVLWHPAQASPSVAD
                     DQDTVLVTDHRPDPRLLEAHPRLRVVVTALAPTGLADEHLFPLGALADDAAMRLLLTHV
                     RRVRPAFKPEPANQAALMGLVHELDGLPSALEFAAGWFMVYSPQHLLDRLRTNPLDPTS
                     AHLRDSLRRSLSTLDDDGRRLLVRLAEGDEPEHGRSLRELCVRGLVRRVGPRHEVLNLV
                     RSAVLEPMSGPHLAGGVALTGPC"
     misc_feature    9907..9921
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            10001..12607
                     /locus_tag="BM417_RS03205"
                     /old_locus_tag="SAMN04488564_101646"
     CDS             10001..12607
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="BM417_RS03205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101646"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_177320253.1"
                     /sec_met_domain="DUF4135 (E-value: 4.2e-106, bitscore:
                     351.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4e-18, bitscore: 61.2,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSAAETSTGESWTAAFAHALRPLIDASRTEVAPPFDAAFAEQLG
                     RRLVAIAARTLVLELHQARDTLTGPSSSERFVEFTRTLSLSSVFNRYPVLARLLAQACE
                     QAVSTHHELSSRFTRDRREIIRTIFENDDPGALISIEMGQGDAHRQGRTVAILTFESGQ
                     KLIYRPRPVGLHARFQEQLDWLSQRTGLDFRTPRLLPRDGYGWLEHIPYEPCADVAGVA
                     EFYKRLGALLALLYAVDGTDMHYENLIACGDQPVLVDVETLFHPTLTPDTDPATLALVR
                     SVHRTALLPHVLLGDNGVADVSGVGGDHGVLSPLDAVDWADAGTDRMRLVRRPKTSSGA
                     LNRPLLHGEPAEPADYQDSLLAGFRAGYDAIVAHRDELLRLVRECVNEEVRFVARATRQ
                     YARLLDESTHPSVLADALDRDLAFGVLVVDDPLLDRLVPFEVSDLWRGDVPLFTCRPGS
                     TDLWTASGLRLPGMLPEPGLHAVTRKILAMSEVDRHDQQWVITALLASRPRPVSHHSGV
                     AVSGHVAPVDPDPARLLVAACGIADQILAHAVTGKDRVNWLGLELVDDRHWTVQPLGAG
                     LSNGYTGVALFLAELGALTGAARYEEFARDALRPLPALLEMFAGEPELVTAVGGGVHGL
                     GGICYGLARLTSLLGLDSELVAQAVRLMPKEDSSLTVVDGVAGSLAAMLAVGTPDSLAL
                     ADHYASTLRGAICPTNGFARGHAGIGWALRRYAATVRDELSDVTARSFLESDAIDPTDT
                     GWCTGLAGVALARDDERLTGLLASRKPLRDMSLCHGELGVVEALAAHHPSAATRRTALL
                     LGALEEHGAHCATPGGVPSPGLFTGLAGIGHGLLRQGFPIPSVLLLQSSPDKEECT"
     misc_feature    12200..12202
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12607..12795
                     /locus_tag="BM417_RS03210"
                     /old_locus_tag="SAMN04488564_101647"
     CDS             12607..12795
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM417_RS03210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488564_101647"
                     /product="hypothetical protein"
                     /protein_id="WP_143138478.1"
                     /transl_table=11
                     /translation="MNESLHRTADQPEQAEHAIGEMELAPKTFAGARARALMGVTMAMS
                     AFVAITPAISDTTVSDK"
     gene            12865..15741
                     /locus_tag="BM417_RS03215"
                     /old_locus_tag="SAMN04488564_101648"
     CDS             12865..15741
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016699815.1"
                     /locus_tag="BM417_RS03215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101648"
                     /product="AAA family ATPase"
                     /protein_id="WP_093588191.1"
                     /transl_table=11
                     /translation="MQTRAPHVVGRDREVTAITRALEHTRESRGGAVFLTGEAGIGKSR
                     LARYAAGHAYDEGMRVLKGRGTTIGPMVPFRPIAEALLGLFRGEPPDDSALGPYKPVLG
                     TLIPEWHDHRSTKESVVVLAEAVLRLLASVARKTPCLLVLEDLHEADAETLAVVEYLAD
                     NLEDQPVLLLATIRTEPGHALELVHRMGQRGSGRLVELRRLSQDEVGQMTAACLDSALI
                     PAELVDRLWTDSAGNPFVIEELLHGMVSGGLLVAGAHGWQVLGELKLPVPAAFVRSVAH
                     RTDRLGPQGREVLSIAAVLGHRFPLSVVQKVTGTDDRELLSHLHAGVAAQLVTPDEPAP
                     DWYAFRHPLTADALLAHLTPAERVDLSWRTADAIEDLHAGLPGDWCPLVAKLRFDAGSR
                     TQAGLLFAEAGRRALAGGAAESAVTLLDRAQSLLTDEAGARADVLDTLLPALAETGDFE
                     RAFALEMNDLQVLDGPRRAKLHTRLSRVAYLAGWFTEGVEQVRVARTLLGPDAPDELAA
                     QLDVNSAYLTLNIPSADRISSAAGLARQAASAADRAQLPMVACEAWQLLGIIAREQDIE
                     EANTCFSKALALADAHQMPIQHVYALVRLAGNDWLQHGSTASLGRTHAEACRTGAITVA
                     HNVDAILALQSVLTGDYAVAADEIDRCLRTTTRLRFHALTRYLLMAKATLAAHRGNRAE
                     TDDAISEFEAVAKSGAQEYPLCFGLARAFCALLEENHALAMAELDRALALESQNPTTFH
                     LSGTHGMRVLLGVLDGRFGWSDYWELTAASASGMRWNRQFTELAHAVLLGRDNRFAEAL
                     EAFQLAQEASELYPLARHLGRRLIAAEAAEWGDPVSWLRSAEEYFHQATIPAVASACRG
                     LLRQAGAPVQQRRNGTEQVPRQLRGHGVTVREFEVFVLLADRMGNKAIGTRLHISPRTV
                     EKHVASLIAKTGQPDREALSTYAAAFGR"
     gene            15855..16841
                     /locus_tag="BM417_RS03220"
                     /old_locus_tag="SAMN04488564_101649"
     CDS             15855..16841
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682144.1"
                     /locus_tag="BM417_RS03220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101649"
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_093588192.1"
                     /transl_table=11
                     /translation="MRKIVLAPLCALVTVTVAACSPSGPEQTNPELAPRGTPMTKVKPT
                     RQDLTTKISITGKVEMNPTFGLVAPVAGEVRYFDVPAPNGTPTRPIRVATVWKDQTPNY
                     VEAPPGSTFSGRLVDDKATVTAGMPIASAKHVGYAIVGDIDGQQAYKINGALTDVVVQI
                     KNGPGPFPCTVLGTIAALPQGTIPEKPPATPDTKDEKKDQPQQTQPKDQPQQPSTSTGL
                     RIVCTAPADVQMINGASASIEVTTGKSAQALVVPVEAVAGSQGKGKVDVIAGDGSRRTT
                     DVTLGLTDGKVIEVKSGLTGDEELAVPGPNLPEGQQQGGDQTKPTGP"
     gene            16841..17551
                     /locus_tag="BM417_RS03225"
                     /old_locus_tag="SAMN04488564_101650"
     CDS             16841..17551
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682143.1"
                     /locus_tag="BM417_RS03225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101650"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_093588193.1"
                     /transl_table=11
                     /translation="MTQSFDQPTVQVQAPLLQLNGITKVLKGQGEPRTILSGVDFTVHP
                     GQSVAILGRSGSGKSTLLSLIGLFDRADEGQYFLHGNDITKLPERRAAALRSAEFGFVF
                     QRFFLLKHLTAAQNVAMALVNGQGWSARRKRKQQVMEALEQVGIAHLAKSKPTRLSGGE
                     QQRVAIARALVRQPRIILADEPTGALDTETGNLVVEVLLNTTRQGCGLVLVTHDHDHAR
                     KMGRVMELRDGRFN"
     gene            17551..18879
                     /locus_tag="BM417_RS03230"
                     /old_locus_tag="SAMN04488564_101651"
     CDS             17551..18879
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099847.1"
                     /locus_tag="BM417_RS03230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101651"
                     /product="ABC transporter permease"
                     /protein_id="WP_093588194.1"
                     /transl_table=11
                     /translation="MLSGKFRSALVIGGQGIRARKLRTFLSMVSLFLGVLAVVAVQAGS
                     EIAERAMLTDVELQSGKDGTIRGYVPGEKGAPAIVESTLKGRTDAVAMISSNAIIGEPG
                     VRPINEGGMPFEYAGQGRGYYGPTMICDSNGSCQEQKQPEKKPDGQAIEVSMVALTGDI
                     RAFKPFRPVSGSWLDFGSAPALAPRIVLNEEAAKGLRQYRVPGEMTIEGATHHVTPQII
                     GVVQDGDMQPRVYMRLDELRTWMPSATETTNSNQYRGGGTSLDLFLQPGSDDLQQLLKA
                     KLIGAGVSQEQMQFQAVKSKERMESELRIMRLIFLGMAFLVLLIGVAGILNVGLATVGE
                     RVEEFALRRAVGMSRLLLAGIVLAETLLTGLLTAALAIGAGAAGLQVALMMFGSRFPSL
                     VGTAFPWEAGVAGVIAGLIAGVLGGLIPAIRAAQIPIATVMRA"
     gene            complement(18947..19732)
                     /locus_tag="BM417_RS03235"
                     /old_locus_tag="SAMN04488564_101652"
     CDS             complement(18947..19732)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667059.1"
                     /locus_tag="BM417_RS03235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101652"
                     /product="aldo/keto reductase"
                     /protein_id="WP_093588576.1"
                     /transl_table=11
                     /translation="MPQLGFGVWQVPDAEATPAVAEALKAGYRSIDTAAAYGNEAGTGA
                     AIAQSGVDRDDVFVTTKLWNADHGYDSTKRAFDESLRKLGLDVLDLYLIHWPTPARDNY
                     VDTWKAFVELQKEGRVRAIGVSNFQPAHLRRLIDETGVVPAVNQIEVHPYFQQNEVRAF
                     NAQHGIQTEAWSPLGQGGELLSDPVVQKIALAHGKSAAQIVLRWHLQIGNVVIPKSVTP
                     SRIRENIDVFGFELPGAEIEALSTLDRGGRIGPDPDKLN"
     gene            complement(19788..20552)
                     /locus_tag="BM417_RS03240"
                     /old_locus_tag="SAMN04488564_101653"
     CDS             complement(19788..20552)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-119). E-value: 1.9e-07. Score:
                     23.1. Matches aSDomain:
                     nrpspksdomains_BM417_RS03240_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667058.1"
                     /locus_tag="BM417_RS03240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101653"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_093588195.1"
                     /transl_table=11
                     /translation="MDLSGRTALVTGSTAGIGFATAEGLLKAGAAVVITGRAEDRVAEA
                     VGKLSAHGDVRGVAADLATAEGAAELIRQVPDVDVLVNNLGIYGAKPVFEIDDAEWQRF
                     FDTNVMSGVRLARHYTPRMVERGWGRVIFVSSESGVFTPTEMVHYGMTKTAQIAISRGM
                     AQEVKGTGVTVNSVLPGPTLTPGVEEFIRERVGDGGEAEFVRTERPTLLLGRLIRPHEV
                     ANLITYVASDLSSATTGAALRVDGGTAPTLIP"
     aSDomain        complement(20196..20534)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM417_RS03240_PKS_KR.1"
                     /evalue="1.90E-07"
                     /label="BM417_RS03240_PKS_KR.1"
                     /locus_tag="BM417_RS03240"
                     /protein_end="119"
                     /protein_start="6"
                     /score="23.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSTAGIGFATAEGLLKAGAAVVITGRAEDRVAEAVGKLSA
                     HGDVRGVAADLATAEGAAELIRQVPDVDVLVNNLGIYGAKPVFEIDDAEWQRFFDTNVM
                     SGVRLARHY"
     CDS_motif       complement(20442..20528)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM417_RS03240_0001"
                     /evalue="7.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="BM417_RS03240"
                     /protein_end="37"
                     /protein_start="8"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LVTGSTAGIGFATAEGLLKAGAAVVITGR"
     misc_feature    complement(20574..20588)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.57"
                     /tool="antismash"
     misc_feature    20575..20586
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(20581..20596)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.54"
                     /tool="antismash"
     gene            20636..21073
                     /locus_tag="BM417_RS03245"
                     /old_locus_tag="SAMN04488564_101654"
     CDS             20636..21073
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034736.1"
                     /locus_tag="BM417_RS03245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101654"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_093588196.1"
                     /transl_table=11
                     /translation="MSLDDDAVQARAQGWRTLAALHARIEDRLERALQKAHGLSVSEYT
                     VLDVLNRQDGFHLRMNQLSNAVVLSQSATTRLVTRLEDRGLLSRYLCPTDRRGIYTEVT
                     GKGHELLALARPTHDEVLAASLEEAAGAPELKPLVEALAKL"
     gene            21096..22187
                     /locus_tag="BM417_RS03250"
                     /old_locus_tag="SAMN04488564_101655"
     CDS             21096..22187
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019640.5"
                     /locus_tag="BM417_RS03250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488564_101655"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_093588197.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.1e-06, bitscore:
                     23.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.7e-09, bitscore:
                     31.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLHALIRAEAPVAEQQRALTEPVLAALVDHGVHRMIAPKRYGGA
                     ELGLPEWSREVQELSRSDASTGWTAMTTTISSSLAWYLPQEAADEVFSDPRALIAGTAA
                     PLGKAVEADGGYRVTGRWGWGSAVAYSSWVIGGTLTPVGPRLAVYPREDVTIHDTWHAA
                     GLRATSSHEFSLTDAFLPSRRAVWPIGITPGIEGPITVFPYFSFLAVGVASVCLGVARR
                     AIDEIEALAVEKVPQYATSRLAEQTGVQIELALMEARLSSATAFLHEALSAAWDAALTG
                     AAAADPVKARLRLACSFASGEATDVAQKAFAAGGGSSVFESSALQRCLRDVHVAAQHTV
                     VSRRMLETYSMLKLGLAPDMTRF"
ORIGIN
        1 gcgtgcggcg ggcgcagcgg cacgtgctgg ggttgccgtc gatccgggac gtcgccgact
       61 acctggaacg gatcgtgcac cgcaaccgga agctggtgcg gatgtgaaag ggcggcgcct
      121 cccccagatc tcagggatgg aaggcgccgc ccctcggcga actcgtggag ctattgcagg
      181 gtcaggttcc aggagttgat gtacccggtg tcaccggagt acacgtcctg gacccgcagc
      241 ttccacgtgc ccgccgcgac ctcggacgag gcgttgaccg tgtaggtcgc caccacgttg
      301 ccggcactgt ccgaagagga cgagttcttc agccggtagg cggtgccgtc cggcgcgatc
      361 aggtcgatca ccaggtcacc gcggtaggtg tggacgatgt ccacgccgac cttggtggcc
      421 gaggaggcgt tgcccgtcac cgtggaggtg atggacgacg tcacggcggt gccgcggtcc
      481 gggatggcga cgtcggtcgt gttctccagg ccaccggagg gcggcggagt cgtgtcgacg
      541 gcgttcacgg ccttggtggc gtccgcgagg cccgcgccac aaccgccgga gcaggtgccg
      601 ggcagcggac gggagttcgt cttgatcagg tccttgacct gggccggggt cagcgacggc
      661 ttcttcgcca ccagcagtgc cgcgaggccc gcgatgtgcg gggcggccat cgacgtgccc
      721 tggtagggct tgtagttctc ggcaccgggg gtggtggtgc cggcgttcag cgtcgaccag
      781 atgccgttct ccggcgtggt gatggtgccg ggggtgtcgg tgccgcgacg ggtctcgccg
      841 ccgggcgccg cgatgtcgat gcgggtgccg aagttcgagt agaacgcctt gttgccctca
      901 cggccggtcg ccgcgacggt gataacgccg ttgcagttgg ccggggtgaa gttggcgacg
      961 ttggcgttcg agttgccggc cgcgacgacg accgtggtgc cgcggttgat ggcaccgttg
     1021 atcgcgttct ggtaggtcgt cgagcaggac gactgaccgc ccagcgacat gttgatgacc
     1081 ttggcgacgt tggtgttcgc gggaacgccg ctcaccgtgc cgccggacgc ccaggtgatc
     1141 gcgtcggcga tgtccgaggt ggcgccaccg cacttggcga gcacgcgcaa cggctggatc
     1201 ttggcgtcgt aggcgatgcc cgcgatgccc ttgctgttgt tcgtggacgc ggcgatcgtg
     1261 ccggcgacgt gcgtgccgtg ccaggacgaa ccctggtccg cggccggaac gggctggccg
     1321 ttggcgtccg tgccgcactc accgcgtgcg gtccagtcgc cctcgtcggc cgggttggag
     1381 tcacggccgt tgttgtcacg agcgcgcgcc gaatcggaga caaagtcgta ccccgcgacg
     1441 accttggacg ccagatcgct gtgcgcgacg tagccggtgt cgatgaccgc gacggtcaca
     1501 ccggtgccgg tgctgctgga ccacgcgccg ggcacgttca tgcccgcggt ggcctcgaag
     1561 aggtcccact gccgggagta ctcggtgtcg ttcgggtcgg cgaacggctg catcagcagg
     1621 tccggctcga cgtaggcgac cttcgggtcg ctcttgaacg cctggatcgt gctgtcggcg
     1681 ttcgtggtct tcgcgccgag gtcgacgacg accgcgccac tcgccgtgcg gcggtgaacg
     1741 gacttgccct tcttgcgggc gtcgtccgag gcagcggtgt cggacgaggc ctcggcggtg
     1801 ccgggcttgt agccgacgat cagccgctcg aagggtcggt tcacctgggt cgagtccggc
     1861 tgggactgga tctggcttgg agcggcgttg acgggtgaga caacgctgaa cacggcggcg
     1921 gaaactgccg cggcgcacag gctcgtgcgt cgcaatccgt tcacgtgagg tccttccacg
     1981 cagggccttc gcgtgccgtt gagggcgtca gtgttctgaa ccggctgcgg aggtggaggg
     2041 accgtaagcc gggtcacagg cgcgaaaaca ggtctagcgg aggccgttta acgacactgg
     2101 cgtgttcacg acaggggtat tgcgctgaat ggcgcacaat gtggccgtgt tgggacacct
     2161 gggcgtcaac gcggaacaga ccgctgttta cgagcttctg gtaacgggcg gcagccgcac
     2221 gaccgacgag atcggcgcgt cctccgccct gctggagtcg atgcgggagc tcggcatggt
     2281 ccggcacctg cccggcgacg tgtggcaggc cgtcccgccc gacctcgccg tggaggcgct
     2341 gatcgcggcc cgcgaggagg ccaaccgccg ggcccgcgcg gacgtcggcc cgttgatgga
     2401 gctgtacctg cgcaaccgcg acgaggagct ggcggacaac gcgttcgtcg aggtggtgtc
     2461 cggaaaggac gccgtgcgcg atctgtggcg gacgctgctg ggcggcgcgc gcgaggaggt
     2521 ctgcgtcctg gaccagccgc cgtacctgtc gccgcaggag gagcacgccg agctggagga
     2581 ctcgacgcgg cagcgcgacg tgcagtggcg ggtggtctac gacaggtccg ctgtggacct
     2641 gccgggccgt gtcaccgaga tcatcgaact ggtcgcggcc ggcgaacggg cccgcgtcac
     2701 gccgacgctg ccgttcaagc tcgccgtgat cgacgcgcac gcggccgtgc tgccggtggc
     2761 gtccggcgac gtgatcgaca aggtgctgct gatccggccc tctgccctgc tggacgtgct
     2821 gcgctcgacg ttcgagctgt actgggacaa gggaatcccg ttcagccccg gcggcatcta
     2881 cgcggcggcg gccgacgtgg acccgaacct gctcgggctg ctcgccgccg ggctgaccga
     2941 cgagtcgatc gcgcgccagc tcgggctcgc gccgcggacc gtgcagcggc gggtgcggca
     3001 gctgatggac cggtgcgggg cgcagacgcg gttccaggcg ggcgtgcagg ccatgcggcg
     3061 aggctggctg tagccgacgc aacctccggt gatcttgtgg cgtattcacc cacagcaagc
     3121 aagttctcac cagggggatt caacaatgcg catgcgcaag gtgatggcgg ctgccctgac
     3181 gggcctcgca ctgatcggtc tcgcgggcac ggcatcggca tcgggttccg gggacctcgt
     3241 gtggccaccg aaggacgtca cgccggtcca caagaccaag gcggagctgg agaagcaggc
     3301 ggccgggttc accgctcgcc agcggcagac cttcccgaag gtcttccacg gcgcgcagaa
     3361 cgtcgctccc ggcaactggg gtggcgaggc cgagggtctg ttcgacgaca tgcagtacct
     3421 gaccaactgg accgagttca ccgtcggcga ccagggccgc acggtgttca tgcaggtcaa
     3481 cgcgccgggc ttcttccggg agtcgccggc gcagctctgc gagcgggaca agtgcaccgg
     3541 caggacgagc gaccaccgcg gtggcgtgac ggtcttcacc aagaacgacc tgcacggcat
     3601 cacggtcgcg tggaacttcc gccgcaacgg tgaggtggtc tgggcgcaga gctggacgcc
     3661 gggcaccgag gcgcagctgg cggccgtggc ctccgaccgc gcgtacacgt tcacgaggta
     3721 gttcctgaga gagcgggcgc ttccggtcat ggagtcaccg gaagcgcccg ctcgatcagc
     3781 tggcgacctt gcgcgcggcc accagctgcc cgtccgcgaa cccctcgacg cgcacctcgc
     3841 gcccggtcgc ggtcaacgtc gcggtgtgcg cgccgtcggt cacgtccagc gaggtggcgg
     3901 ggcggccatc gacgtagatg tccacccggt cgaggttcac ggtgtccagg gagacggtcg
     3961 ttccctcgac cgccactccg agccgccgca ccgggagcgc ggccagcagt gagcccgccc
     4021 gtgcgagcag gtccacgttg ccctgcaaca ggtccgcgcg cgtgaccttg tgctggtgcg
     4081 tcgggcgcac acccaggtcc tccaccggcg tgccggcgag cttgccgacg cgcaacgtgc
     4141 ggcggatcga cacgcgcatg ttcgccctgt tgggcaacga cttgtacggc gactcgccgt
     4201 cgcccggcgc cgggatcttc agcagtgtca tcagcagccc gtgcgtccac acgttcgcgc
     4261 cgcccgcgcc ggtgttgtcg tccacaccga ggatcgggcc caggtcgtgg tcggcccagc
     4321 ccgcggcgaa gatgtccgtg gccgagtagc agcgcgcgtc ggtgatcagc agtaccggac
     4381 cgtggtacgt ctggcccacg gcgttcgcgc cctcgaccgg cgtgatcgtg tgcgagcagg
     4441 agaacgcctg gcccgtctcg gtcgagctgt cgagcgacgg gaaccacggg ccgaggtcga
     4501 tctggccggt cgggttctcg gcgtggcggc gggagatccg caggttcagc ggcgtgctca
     4561 ggaactgcac gggctccggc tgcacgggtc gtggcgtcat cgtctggagc aggaactccg
     4621 aggcgaagat gtggccgccg ccgttgtcgc ggacgtcgac gatgagtccg ttctgcggca
     4681 ggaggttcgc gagccggacg aactcggcga ggaacgcgtc cgggtcgtcg acgctgaacg
     4741 tgaagatccg caggtgcccg aacgtgccgg acggcgtggt gatcggacgc gcgcggaaca
     4801 cgccgggcat cgtcgtcgcc acgtcctgcg cggccatcgc gaccgcgcca ccggcggcct
     4861 cggcctgcac gaccttgggc gcgtgcaaca acttcttggc gcgcgccttc tcgtcggagt
     4921 ccaggtcgac gccctgcgcg gccgcggcgg ggctgagcga gtcgacgtcg gtcatcggag
     4981 ggaggttctc cgtgacctgc cagtcgacgc ggatgtcggc ggcggcgccg gtctcgtcgc
     5041 ggtaggtgac gacgacccag tcctcgtcgg gcggaagttg gatcaccaag gggcgcaacg
     5101 tgagcgactc caggccgcga gcgtggttcg cggcggcgtt gctgcccgcg aagaccgcgc
     5161 cgttcaacgc gaccgcgcgg gcgatcggcg tgccgttcca gtgcgtcacc tcggcgccga
     5221 ccgcgaggcc gttgaagttc gcgaccgtgc gggcgacgag gtactgctcg gtgccgtcgg
     5281 cggcgaaaca acgctccagc tggaacggca ggaaggcgat cttgcccgcg aacggcgcgg
     5341 gcagcaggta gttcgtgtgc aggtcgcgca ccgagtggaa ggtgctcgac agctcgcggt
     5401 ggaactgcca ctcggcctcg gccgtggcat cggtctgccg ttcgagtctg gctcggagca
     5461 ccctgagtct ttgcacagga ttcaccgcgt gcatggcgac cttgagagga aggtgcgcgt
     5521 agttctgctc cagcaggatc agcgcctggt cgacgatgag cttgcgctgc gccagggtga
     5581 gggtgcccgc cgtcgcgagg aactcggcga gtccgacgga gtttgcgacg ttcgggtgag
     5641 cggttgtggt catggtgggg cctccttgtc cagtagaggc tttccagggc gcctggatac
     5701 acctgtttca cccgttcggc cgctaactgg agcagttttc aggacgacaa ctggagtaaa
     5761 ggggaggccg gtcatgaagc cacgcgtcct ggagctgcgc atccacgggg tcaacaacac
     5821 acccccggac gcgatgctgg cccttcccga gcacgccgtc gaacagttcc gcggcgaccg
     5881 gttcggcagc ttctggcggc cgaagccgga caagctcgcc gagctgccgg cggagcaccc
     5941 cgggcaggtg cccgcggccg tgcggcgcga ggcgtactcg tggggcggca tggcgcgcag
     6001 cagtccgggt gtgccgggca gcggggtgcc gtccgtgctc gcgaacgcgc tggggcgcgt
     6061 cggatgggcg ctgctgctgc cgttcgggct ggcgaacgtc gcctactggt cccggaagct
     6121 ccccgacgac tcgacaccga cgaccaggca catggtgtgg tggaacgccg ggcgcggcgc
     6181 ggccagcacg cggttgttcg ggctggggct gacggtgttg ctggtgctcg cggtgtgcga
     6241 ggtggcgatc gacgtctacg cgatccagtg ctcgctgccc ggcaccacct gcaagcggct
     6301 gccggacttc ctggacgtgc tcggcgaccc cgcgcggcac gtcagggtgc tcgccgcgtc
     6361 cgtcgtgccg gtgttgctgc tgctcgggct ggtggcgctg acctcgttgt cgcgcagcag
     6421 gtacgagcag gcgacgatgc ggcgcaggcc ggtgcggcgg ccgggcgtga tgctcagcag
     6481 ggcgtcgatg tgggagggca gcccgcggat ccgccggctc acccggctgc acatctcggc
     6541 cgggtgctgc gtggtggtgc tggtgacgag cgcgcagctg tggcggcacg cgttcttcct
     6601 ggtgctgacc gtgctcgcgg ccggggtgct ggcggtcgtg atggcgcggg tcgtggtgac
     6661 ggcgaccgac tgcccggacg tgccgtcgac cgagaagggc ggcctgtggt cgtggctgct
     6721 gatgatctcg gcggtgctcg tgctggtggc gcacgggttc ggcctgtacg cgatcgagcc
     6781 ggccttcgac gggccgttgt ggctgacgtc gtggggaccg ccggtcgtca cggtcgcgct
     6841 gctcgggtcc gtgctggccg cgtggtcgtg gcggcgcaac gacgccaaag ggccgttggt
     6901 catgctcgtg ctgttcgtgg ctttcatggt tgccacgtac tgggttccgc tcgcctggat
     6961 cggcgcggtc gtgttcggcg gggcgctggc gtggcgggcc cggccgcgtg ccggtgacca
     7021 gtggcaggcc tggcgcggcg ccggtcccgg tgtgctgctg gggttgtcgc tgacgtcgtc
     7081 ggtgacgctg gcgaccgtgc tggtgctgac gttccggggc tggatcggca cgggactgca
     7141 ggcgccgccg ttctactcgt ggttcagcgc cgcgttcgcc gtcgcactgg ttccgctggt
     7201 gctgctggtg ctcgcccagg ccgtcgtgct gctgtcgcgg ctgaccaaac ccgccgtgct
     7261 cgacgacgag gccgaggtgc tcgtcgtgcg ggtgcggcac gtggtcgcgg tgacgcaccg
     7321 ggcggagaac gtcgccgggg tgctgtcgac actgggcgtg ctcgccctgg tgctgacctg
     7381 ctacctggcg ttcgcctcgc ccgcgtggtc gcagtggtcc ggtgtgacgt gggtggtggg
     7441 caagggcgac tgggtgaccg ggctcgccgg ggtcgcggtg atcggctcgt tcgtcggagc
     7501 cgggatgctg accaaccggc ggccgctcgg gctggtgtgg gacctcatgt gcttcctgcc
     7561 gcgcaccgcc cacccgttcg caccgccctg ctacgccgag cgcgcggtgc cggagatcgc
     7621 ggacagaacc cgcgagttcc tggacgagtc gcctgatcac cgggtggtgc tgtccgcgca
     7681 cagcctgggc gccgtgctgg ccgtggcggc gctgttcgcg ttgccggagg gctatctcga
     7741 gcgcgtgcgg ctgctcacct acggcgtgca gctgcggccg tacttcgggc ggatcttccc
     7801 cgaactgctg ggaccttcgg tcctgggcac accggacgtg cgcgcgggcg cgatgttctc
     7861 gtgcgatccg tggcgccgga atccaggcga tacaccggaa cgcgggctca ccacgttgat
     7921 gggcaagaac tggatcaacc tgtggcgccg caccgactac ctgggttttc ccgtgcacgg
     7981 ctgggaaccg aacgacctcg accgccgcgc cggcgagacg aacgggtcac cggacaaagt
     8041 ggagactcac ggcgactatc acctgtgcgc ggcctatcga gacgcgctca cggagctcgc
     8101 tcgcccgatc tgaaccagtc acccgatcgt ggacgtgaag ggggtgggaa cctggaacgc
     8161 agttgactca aggagaaaca tgcgcacgac tgtggcgacc ctcgtgggag ccgtactgct
     8221 caccggaggg ctggccgcct gttcgagcga gcccgcaccc tcgtccgcac ctcagaccca
     8281 ggccgtgaaa ccggtggccg agaccgacgt ggcggcacct gcggcgtccg gtgaccagcc
     8341 gaaaggcatc acctacgacg tggcgcggat cccgttgggc gccaagctct cgaccggctc
     8401 gtccgtcgcg aatggacgga ccacggtgga gctgaaggtg tccggcctgc tgccgaacac
     8461 gaagtacggc tcgcacgtgc acaccaagcc gtgcggcgcc aagccggccg actcgggccc
     8521 gcattaccag aacgagaagg acccggtgtc gccgagcgtc gactcgaagt acgccaacgc
     8581 gcagaacgag atctggctgg acttcaccac cgacgcgcag ggtgccgcga ccggcacggc
     8641 gacggtgagc tgggagttcc gcaagggcga ggcgaacgcc gtcatcgtgc acgccacgca
     8701 ctccagcacc gagcacggca aggcgggcac cgctggtgac cgcctcgcgt gcctcaccgc
     8761 tgcgttctaa cacggcccgg tcagggccac tcctcccgcg aggtgtggtc ctgacatcgg
     8821 ttccagcacc gccgaacgca cgaggttcag cacctcgtgc cggggtccga cgcgacgaac
     8881 gagcccccgc acgcacagtt cccgcaggga ccggccgtgt tcgggttcgt ctccctcggc
     8941 caggcgcacc agcagccgcc gcccgtcgtc gtccaatgtg gacagcgagc ggcgcagcga
     9001 gtcgcgcagg tgtgccgagg tcgggtcgag cgggttggtc cgcagccggt ccagcaggtg
     9061 ctgcggcgag tagaccatga accacccggc cgcgaactcc agtgcggacg gcagcccgtc
     9121 cagttcgtgc acgagaccca tgagcgcggc ctggttggcc ggctcgggct tgaacgccgg
     9181 ccgcacccgg cgcacgtgcg tgagcagcaa ccgcatcgcg gcgtcgtcgg ccagcgctcc
     9241 cagcgggaac aggtgctcgt cggccagccc ggtcggcgcg agtgccgtga cgacgacccg
     9301 cagtctcggg tgcgcctcca gcaggcgcgg gtccggccgg tgatcggtga cgaggaccgt
     9361 gtcctggtcg tcggcgacgg acgggctcgc ctgcgccggg tgccacagga ccgaccagcc
     9421 gtgccggaag tgcagctcgc ccgcgacctc cagggcgagc cgggtcttgc cgacgccgct
     9481 gacgccggtg acggtgacca gccgccgcga ctcgtagcct ccggcctccg gccgtccctc
     9541 cgtcagcaac gccgccagcg ccgcagcctc cgcctcccgt cccacgatca tcccggcggg
     9601 cccggccggt gcgggcggtg ccacggcggt gcggcccgcg gatcggcctc ccgcctgttg
     9661 caggtccgcg cggctgccgt cgtcgagccg cagcccgtcg gcgagcaggc gcaccgtctc
     9721 ggctcgcggt gagcgggtgc gaccgcattc caggtcgcgg atggcccgca cgctcaccat
     9781 cgcgaagtca gccagctgtt gctgggtgag gcccgcgccg atgcggtgcg tgcgcagcag
     9841 ttctccgaac tccctcatcc cgttcccctc cctcggacat cgagtctcgg gtgaatcggc
     9901 cgccgaaaca tgggtggcga tcccccatat tcacgtccgc ccgcaaatct ggggggttgg
     9961 tccccatgtg ccgcccgccc gcgcgtgcga ggttggccgg gtgacctccg cggccgagac
    10021 cagcaccggc gagagctgga cagcggcttt cgcgcacgct ctgcgcccgc tgatcgacgc
    10081 gtcccgcacg gaggtcgcgc cgccgttcga cgcggcgttc gccgagcagc tcggccgccg
    10141 gctggtggcc atcgcggcgc ggacgctcgt gctggagctg caccaggcgc gcgacacgct
    10201 gaccgggccc agcagctccg agcggttcgt cgagttcacc cggacgctga gcctgtcgtc
    10261 ggtcttcaac cgctacccgg tgctggcgcg gttgctcgcg caggcctgtg agcaggcggt
    10321 ctcgacccac cacgagctgt cgtcgcggtt cacccgcgac cgccgggaga tcatccggac
    10381 gatcttcgag aacgacgatc ccggcgcgtt gatctccatc gagatgggcc agggcgacgc
    10441 gcaccggcag ggccggaccg tggccatcct gaccttcgag tccggtcaga agctgatcta
    10501 ccggccgcga ccggtcgggc tgcacgcgcg gttccaggag cagctcgact ggctctccca
    10561 gcgaaccgga ctcgacttcc gcacaccgcg gctcctcccc cgcgacggct acggctggct
    10621 ggagcacatc ccgtacgagc cgtgcgcgga cgtggccggg gtcgccgagt tctacaagag
    10681 gctcggcgcg ctgctcgcgt tgctctacgc ggtcgacggc accgacatgc actacgagaa
    10741 cctcatcgcg tgcggtgacc agccggtgct cgtggacgtc gagacgctgt tccaccccac
    10801 gctcacaccg gacacggatc ccgcgacgct cgcgctggtg cgttcggtgc accgcacggc
    10861 cctgctcccc cacgtgctgc tgggcgacaa cggggtcgcg gacgtgtccg gggtcggcgg
    10921 tgatcacggc gtgctgtcgc cgttggacgc ggtcgactgg gccgacgctg gaaccgaccg
    10981 gatgcggctg gtcaggcgcc ccaagacgtc gtcgggggcg ctcaaccggc ccctgcttca
    11041 cggtgagccc gccgaacccg ccgactacca ggactcgctg ctggccgggt tccgcgcggg
    11101 ctacgacgcg atcgtggcgc atcgcgacga actgctgcgg ctcgtgcggg agtgcgtgaa
    11161 cgaagaagtg cggttcgtgg cacgcgcgac acggcagtac gcgcggttgc tggacgagtc
    11221 gacgcatccg tccgtgctgg ccgacgcgct cgaccgcgac ctggcgttcg gcgtcctcgt
    11281 ggtcgacgat ccgctgctcg accggctggt gccgttcgag gtctccgacc tgtggcgcgg
    11341 tgacgtgccg ctgttcacgt gccggcccgg gtcgaccgac ctgtggaccg cgtccgggct
    11401 ccggcttccg gggatgctgc cggagcccgg actgcacgcc gtgacgcgca agatcctggc
    11461 gatgagcgag gtcgaccggc acgaccagca gtgggtgatc acggccctgc tggcgtctcg
    11521 gccgcgcccg gtgtcgcacc acagcggcgt cgcggtgtcc gggcacgtcg cgccggtcga
    11581 tccggatccg gcccggctgc tggtcgccgc gtgcgggatc gccgaccaga tcctcgcgca
    11641 cgcggtcacc ggcaaggacc gcgtcaactg gctcgggctc gaactggtcg acgaccggca
    11701 ctggacggtg cagccgctcg gcgccggtct gtccaacggc tacacgggcg tggcgctgtt
    11761 cctggccgag ctgggcgcgc tgaccggcgc cgcgcgctac gaggagttcg cacgcgacgc
    11821 cctgcggccg ttgccggcgc tgctggagat gttcgccggg gaaccggagc tcgtcacggc
    11881 ggtcggcggc ggagtccacg gcctgggcgg catttgctac gggctcgcgc gtctcacttc
    11941 gctgctcggc ctggacagcg aactggtggc gcaggccgtt cggctgatgc cgaaagaaga
    12001 ttcgtcgctc accgtcgtgg acggcgtagc gggctcgttg gccgcgatgc tcgccgtggg
    12061 cacgccggat tcgctcgcgc tggccgatca ctacgcctct actctgcgtg gcgctatttg
    12121 tcccaccaat ggtttcgccc gtggccatgc gggaatcgga tgggcgctga ggcgttacgc
    12181 ggcaacggtt cgtgacgagt tatctgacgt gaccgcacga tcgttcctgg agagcgacgc
    12241 catcgacccg accgacaccg gctggtgcac gggtctggcc ggtgtcgcgc tcgcccggga
    12301 cgacgagcgc ctgacaggct tgctggcgtc caggaaaccg ttgcgggaca tgagtctctg
    12361 ccacggcgaa ctgggtgtcg tcgaagcact ggccgcgcac caccccagcg ccgcgacccg
    12421 tcgcacggcg ttgttgctgg gagcactgga ggaacacggc gcacactgcg ccaccccggg
    12481 cggtgtgccg tcaccaggcc tgttcacggg cctggccggc atcggtcacg gcctgctgcg
    12541 ccaagggttc ccgatcccgt cggtcctgct actgcaatcg tcacctgaca aagaggagtg
    12601 cacctgatga acgagtccct gcaccgcacg gccgaccagc ccgaacaggc cgagcacgcg
    12661 atcggggaga tggagctcgc gccgaagacc ttcgcgggtg cgcgggcgcg tgcgctgatg
    12721 ggtgtgacca tggcgatgag cgcgttcgtg gcgatcacac ccgcgatctc ggacaccacg
    12781 gtgagcgaca agtaggaaac tttcacccct aatacgcctg ggcagccgat acggagaact
    12841 gcacaggacc gttagggtcc agacatgcag acccgagcgc cccacgtggt cggccgtgat
    12901 cgcgaggtca cggccatcac gagggcactc gaacacacgc gcgagtcccg tggcggcgcc
    12961 gtcttcctca ccggggaggc ggggatcggc aagtccagac tcgcccggta cgcggcgggc
    13021 cacgcgtacg acgagggcat gcgggtgctc aaaggacgcg gcacgaccat cgggccgatg
    13081 gtgccgtttc gtccaatcgc ggaagcactt ctgggtctct tccgcggcga accgccggac
    13141 gactccgcgc tcggcccgta caaaccggtg ctgggcacgc tgatcccgga gtggcacgac
    13201 caccggtcca cgaaggaatc cgtcgtggtc ctggcagagg cggtgctccg gctgctcgcg
    13261 tccgtcgcgc gcaagacgcc atgcctgctc gtgctcgagg acctgcacga ggcggacgcg
    13321 gagacgctcg cggtcgtgga gtacctggcg gacaacctgg aggaccagcc ggtcctgctg
    13381 ctcgccacga tccgcaccga acccggccac gcgctggaac tcgtgcaccg gatgggacaa
    13441 cgcgggtccg gcaggctggt ggagctgcgc cggctctcgc aggacgaggt cgggcagatg
    13501 acggccgcct gtctggacag cgcgctgatc ccggcggagc tcgtcgatcg cttgtggacg
    13561 gacagcgccg gaaacccgtt cgtcatcgag gaactgctgc acggcatggt gagcggcggc
    13621 ctgctcgtgg ccggggcgca cggctggcag gtgctgggcg agctgaaact gccggtgccg
    13681 gcggcgttcg tgcgcagcgt cgcgcaccgc acggacaggc tggggccgca gggccgcgag
    13741 gtgctgtcca tcgcggcggt gctgggccac cggttcccgc tctccgtggt gcagaaggtg
    13801 accggcaccg acgaccgcga actgctcagc cacctgcacg ccggggtcgc cgcgcagctc
    13861 gtgacgccgg acgagcccgc ccccgactgg tacgcgttcc ggcacccgct caccgcggac
    13921 gcgttgctgg cccacctgac cccggccgaa cgcgtggacc tgtcgtggcg cacggccgac
    13981 gcgatcgagg acctgcacgc cgggctgccc ggcgactggt gcccgctcgt cgcgaagctg
    14041 cggttcgacg ccggatctcg gacccaggcg ggacttctgt tcgccgaggc gggcagacgg
    14101 gcgttggccg gtggcgcggc ggagtcggcc gtcacgttgc tcgaccgcgc gcaaagcctg
    14161 ctgaccgacg aggccggcgc ccgcgccgac gtgctggaca cgctgctgcc ggcgctggcc
    14221 gagacgggcg acttcgaacg cgccttcgcc ctggagatga acgatctcca agtcctggac
    14281 ggcccgcgcc gcgcgaagct ccacacgcga ctgtcccgcg tcgcctacct cgccggctgg
    14341 ttcaccgaag gcgtggaaca ggtacgcgtc gcgaggacgt tgctcgggcc ggacgcgccc
    14401 gacgagctgg ccgcgcagct ggacgtcaac tccgcctacc tgacgctgaa catcccgagc
    14461 gccgaccgga tctcctcggc ggcgggcctc gccaggcagg cggcctcggc ggcggaccgg
    14521 gcgcagttgc cgatggtggc gtgcgaggcg tggcagctgc tcgggatcat cgcgcgcgag
    14581 caggacatcg aggaggcgaa cacctgcttc agcaaggctc tcgcgctcgc ggacgcgcac
    14641 cagatgccga tccagcacgt ctacgcgctg gttcgcctgg cgggcaacga ctggcttcag
    14701 cacggcagca ccgcgtcgct cggccgcacg cacgccgagg cgtgccgcac gggcgcgatc
    14761 acggtggcgc acaacgtgga cgcgatcctg gcgttgcagt ccgtgctgac cggcgactac
    14821 gccgtggcgg cagacgagat cgaccgctgc ctgcgcacga cgacccgcct gcggttccac
    14881 gcgctgaccc gctatctgtt gatggcgaag gcaacgctgg ccgcgcatcg gggcaaccgc
    14941 gccgaaaccg acgacgccat cagcgagttc gaggcggtcg ctaagagcgg ggcgcaggag
    15001 tacccgctct gcttcgggct cgcccgcgcg ttctgcgccc tgctggagga gaaccacgcg
    15061 ctggcgatgg cggagctcga ccgcgcgctc gcgctggaat cccagaaccc caccacgttc
    15121 catctctccg gcacgcacgg catgcgcgtg ctgctcggtg tgctcgacgg ccggttcggc
    15181 tggtcggact actgggagct gaccgcggcc tccgcgtcgg gaatgcggtg gaaccggcag
    15241 ttcaccgagc tggcgcacgc cgttctcctc ggccgcgaca accggttcgc cgaggcgctg
    15301 gaagccttcc agctcgccca ggaagcctcg gaactgtatc cattggcgag acatctgggg
    15361 cggcggctga tcgcggcgga ggcggcggag tggggcgatc cggtgtcctg gctgcgttcg
    15421 gcggaggagt acttccacca ggccacgatc ccggcggtcg cgtcggcgtg ccgtggcctg
    15481 ctgcgccagg ccggagcgcc ggtccagcaa cgccgcaacg gcacggaaca ggtgccgcgg
    15541 cagctgcgcg ggcacggcgt gacggtgcgc gagttcgagg tgttcgtgct gctcgccgac
    15601 cgaatgggca acaaggcgat cggcacccgg ctgcacatct cgccgcgtac ggtggaaaag
    15661 cacgtcgcct cgctcatcgc gaagaccggc cagcccgacc gtgaagcgct ttccacctac
    15721 gccgccgcgt tcggacgtta gtttcgatct gggccgaaac gtcgatgcga catcggccga
    15781 aagactgatg caacctccgg gacctatcgg gtgtccttat cggtaggttg gtcgaaacga
    15841 catgggggac gttcgtgcgc aaaattgttc tcgcgccgct gtgcgcgctg gtcacggtga
    15901 ccgtggctgc gtgcagtccg tcaggtccgg aacagaccaa tccggagctg gcaccgcgcg
    15961 gtacgccgat gaccaaggtc aagcccacca ggcaggacct gaccaccaag atcagcatca
    16021 ccggcaaggt cgagatgaac ccgacgttcg ggctcgtcgc gccggtcgcg ggcgaggtgc
    16081 ggtacttcga cgtcccggcg cccaacggca ctccgaccag gcccatccgg gtcgccacgg
    16141 tgtggaagga ccagacgccg aactacgtcg aggcgccgcc ggggtccacg ttcagcggca
    16201 ggctcgtcga cgacaaggcg acggtgacgg cgggcatgcc gatcgcgtcg gccaagcacg
    16261 tcggctacgc gatcgtcggc gacatcgacg gccagcaggc gtacaagatc aacggcgcgc
    16321 tcaccgacgt cgtggtgcag atcaagaacg gccccggccc gttcccgtgc acggtgctcg
    16381 gcacgatcgc cgcgctgcca cagggcacca tcccggagaa gccgccggcc acgccggaca
    16441 ccaaggacga gaagaaggac cagccgcagc agacccagcc caaggaccag ccgcagcagc
    16501 cgagcacctc cacgggcctg cgcatcgtgt gcaccgctcc cgcggacgtg cagatgatca
    16561 acggcgccag cgcgtcgatc gaggtcacca ccggcaagtc ggcgcaggcg ctggtcgttc
    16621 cggtcgaggc ggtcgcgggt tcgcagggca agggcaaggt cgacgtcatc gcgggcgacg
    16681 gttcgcgccg caccacggac gtgacgctgg gcctgaccga cggcaaggtc atcgaggtca
    16741 agtcgggtct caccggtgac gaggaactgg ccgtgccggg accgaacctg cccgagggcc
    16801 agcagcaggg cggcgaccag accaagccga cgggtccgtg atgacgcagt ccttcgatca
    16861 acccacggtt caggtgcagg caccgctgct gcagctcaac ggcatcacga aggttctcaa
    16921 ggggcaaggg gaaccgcgca cgatcctgtc cggcgtggac ttcaccgtcc atcctggaca
    16981 gagcgtggcg atcctcggcc gttccggctc cggcaagtcg acgctgctgt cgctgatcgg
    17041 gctcttcgac cgcgccgacg agggccagta cttcctgcac ggcaacgaca tcacgaagct
    17101 gcccgagcgc agggccgcgg cgttgcgcag cgcggagttc gggttcgtgt tccagcgctt
    17161 cttcctgctc aagcacctca ccgcggcgca gaacgtggcg atggcgctgg tcaacggcca
    17221 gggctggtcg gcgcggcgca agcgcaagca gcaggtgatg gaggcgttgg agcaggtcgg
    17281 catcgcgcac ctcgcgaagt ccaagcccac caggctttcc ggtggtgagc agcagcgcgt
    17341 ggcgatcgcc cgcgcactcg tgcggcagcc gcggatcatc ctcgccgacg agcccacggg
    17401 cgcgctcgac acggagaccg gcaacctcgt cgtcgaggtg ctgctcaaca cgaccaggca
    17461 gggctgtggc ctcgtgctgg tgacgcacga ccacgaccac gcgcgcaaga tgggccgcgt
    17521 gatggagctc cgcgacgggc ggttcaactg atgctttccg gcaagttccg gtccgccctg
    17581 gtcatcggcg gacagggcat ccgcgcccga aaactgcgca cgttcctctc gatggtctcg
    17641 ctgttcctcg gtgttctcgc cgtcgtggcc gtgcaggcgg ggtccgagat cgccgaacgc
    17701 gcgatgctca ccgacgtcga gctgcagtcc ggcaaggacg gcacgatccg gggttacgtc
    17761 cccggcgaga agggcgcgcc ggcgatcgtc gagtccacgc tgaagggccg caccgacgcc
    17821 gtcgcgatga tcagctcgaa cgcgatcatc ggcgagcccg gtgtgcggcc gatcaacgag
    17881 ggcggcatgc cgttcgagta cgcgggccag ggccgcggct actacggccc gacgatgatc
    17941 tgcgactcca acggctcgtg ccaggagcag aagcagccgg agaagaagcc ggacggccag
    18001 gccatcgagg tcagcatggt cgcgctgacc ggcgacatcc gcgcgttcaa gccgttccgc
    18061 ccggtctccg gcagctggct cgacttcggg tccgcgccgg cgctcgctcc ccggatcgtg
    18121 ctgaacgagg aggccgccaa gggtctgcgg cagtaccgcg tccccggcga gatgacgatc
    18181 gagggcgcca cccaccacgt gacgccgcag atcatcggtg tggtgcagga cggcgacatg
    18241 cagccgcgcg tctacatgcg gctcgacgag ctgcgcacgt ggatgccgtc cgccaccgag
    18301 accaccaact cgaaccagta ccgcggcggc ggcacgagcc tcgacctgtt cctgcaaccc
    18361 ggctcggacg acctgcagca gctgctcaag gccaagctca tcggcgcggg cgtgtcccag
    18421 gagcagatgc agttccaggc ggtgaagtcc aaggagcgca tggagtccga gctgaggatc
    18481 atgcgtctga tcttcctcgg catggcgttc ctggtgttgc tgatcggtgt cgcgggcatc
    18541 ctgaacgtcg gtctcgccac ggtcggcgag cgcgtcgagg agttcgcact acgccgcgcg
    18601 gtcggcatgt cgcggttgct gctcgcggga atcgtgctcg cggagacgtt gctgaccggt
    18661 ctgctgaccg ccgcgctggc gatcggcgcg ggcgccgccg ggttgcaggt ggcgctgatg
    18721 atgttcggca gcaggttccc gtcgctggtg ggcaccgcct tcccgtggga ggcgggtgtc
    18781 gccggcgtga tcgcgggcct catcgccggt gtgctgggtg ggctcatccc ggccatccgg
    18841 gcggcgcaga tcccgatcgc cacagtcatg cgggcctagt ccttggcccg ttgccggcga
    18901 agccccggac cgcttgatgc gggccggggc ttcgtatttc ctggaactag ttgagcttgt
    18961 cggggtccgg gccgatgcgg ccaccacggt ccagagtgga cagtgcctcg atctcggcgc
    19021 cgggcagctc gaagccgaac acgtcgatgt tctcccggat ccgggacggc gtcacggact
    19081 tcgggatcac gacgttgccg atctgcaggt gccagcgcag cacgatctgc gcggccgact
    19141 tgccgtgcgc cagcgcgatc ttctggacga ccgggtcgct gagcagctcg ccgccctggc
    19201 cgagcggcga ccaggcttcg gtctggatgc cgtgctgggc gttgaaggcg cgcacctcgt
    19261 tctgctggaa gtacgggtgc acctcgatct ggttgaccgc cggcacgacg ccggtctcgt
    19321 cgatcagccg ccgcaggtgc gcgggctgga agttggagac gccgatcgcg cggacgcggc
    19381 cctccttctg cagctccacg aacgccttcc aggtgtcgac gtagttgtcg cgggccgggg
    19441 tcggccagtg gatcaggtac aggtcgagga cgtcgagacc gagcttgcgc agcgactcgt
    19501 cgaacgcgcg cttggtcgag tcgtagccgt ggtcggcgtt ccagagcttg gtggtgacga
    19561 agacgtcgtc acggtccaca ccggactggg cgatggcggc acccgtgcct gcctcgttgc
    19621 cgtaggccgc ggccgtgtcg atgctgcggt aaccggcctt cagcgcctcc gcgacggcgg
    19681 gggtggcctc cgcgtccggc acctgccaga cgccgaaacc gagctggggc atggtgacgc
    19741 cgttgttgag cttcacggtg ttcaaagcag aatcctcacg gttgtactta cggaatgagc
    19801 gtcggagcgg tgccgccgtc gacgcgcaac gcggctccgg tcgtcgcgga cgacaggtcc
    19861 gacgcgacgt aggtgatgag gttcgcgacc tcgtgggggc ggatcaggcg gcccagcagc
    19921 aacgtggggc gttcggtgcg gacgaactcc gcctcgccgc cgtcgccgac gcgctcgcgg
    19981 atgaactcct cgacgccggg cgtgagtgtc gggccgggca gcaccgagtt cacggtgacg
    20041 ccggtgccct tgacctcctg ggccatgccg cgcgagatgg cgatctgcgc ggtcttcgtc
    20101 atgccgtagt ggaccatctc ggtcggtgtg aagacgccgg actcgctgct cacgaagatc
    20161 acccggcccc agccgcgctc gaccatgcgg ggcgtgtagt gccgggcgag acggacgccg
    20221 gacatgacgt tggtatcgaa gaaccgctgc cactcggcgt cgtcgatctc gaagaccggc
    20281 ttcgcgccgt agatgcccag gttgttgacg agcacgtcca cgtcgggcac ctggcggatc
    20341 agttcggccg cgccctcggc ggtcgcgagg tccgccgcga caccgcgcac gtcaccgtgg
    20401 gcgctgagct tgccgaccgc ctcggccacg cgatcctcgg cgcggccggt gatgacgacg
    20461 gcggcacccg ccttgagcag gccttccgcg gtggcgaagc cgatgcccgc ggtggagccc
    20521 gtcacaagtg ccgtgcgtcc cgacagatcc atgtctctcc ccggtagact tgttgaagac
    20581 gattacaagc gtacgcaata gttgcacacg ctgtctattc gagaagggtt gacccatgtc
    20641 actggacgac gacgccgtcc aggcgcgcgc acagggctgg cgcacgctcg cggcgttgca
    20701 cgcgcgcatc gaggaccgcc tcgagagagc gctgcagaag gcgcacggtc tctccgtcag
    20761 cgagtacacc gttctggacg tcctcaatcg ccaggacggg ttccaccttc ggatgaacca
    20821 gctctccaac gccgtggtgc tcagccagtc agccacaacg cgcctggtca cgcgactcga
    20881 ggaccgcggc ctgctgtcgc gctacctctg cccgaccgac cggcgcggca tctacaccga
    20941 ggtcaccggg aagggccacg agctgctcgc gctcgctcgt cccacgcacg acgaggtgct
    21001 cgccgcctct ctcgaagaag ccgccggagc tcccgagctc aagccactcg ttgaggcgct
    21061 cgccaagctg tagctgttcg agcaagatcg cgcgcatgga tctccacgcc ctgatccgcg
    21121 ccgaggcgcc ggtggccgaa cagcagcgcg ccctcaccga accggtgctg gccgcgctcg
    21181 tcgaccacgg cgtgcaccgc atgatcgccc cgaagcgcta cggcggcgcc gagctcggcc
    21241 tgcccgaatg gagccgggag gtccaggagc tgtcgcggtc cgacgcctcg accggctgga
    21301 ccgcgatgac gaccaccatc tcgtcgtcgc tggcctggta cctgcctcag gaggccgcag
    21361 acgaggtgtt cagcgatccg cgcgcgttga tcgcgggcac cgccgcgccg ttgggcaagg
    21421 ccgtggaggc cgacggcggt tatcgcgtga ccggccgttg gggctggggc agcgctgtcg
    21481 cttattcctc gtgggtcatc ggtggcacgc tcacgcccgt gggcccgcgt ctggccgtgt
    21541 acccacgtga ggacgtgacg atccacgaca cgtggcacgc cgccggcctg cgcgcgacca
    21601 gttcgcacga gttctctctc acggacgcct tcttgccgtc acgtcgtgcg gtgtggccga
    21661 tcggcatcac gcccggcatc gagggcccga tcaccgtgtt cccctacttc agcttcctgg
    21721 ccgtgggcgt cgcgtccgtg tgcctcggtg tggcccgccg cgcgatcgac gagatcgagg
    21781 cgctggccgt cgagaaggtg ccgcagtacg cgacgtcccg cctcgccgaa cagaccggcg
    21841 tgcagatcga gctcgcgctg atggaggcac ggctgtcgtc ggcgacggcg ttcctgcacg
    21901 aggcgctgag cgcggcctgg gacgcggcgc tgaccggtgc cgccgctgcg gatccggtga
    21961 aggcacggct tcggctggcc tgctcgttcg cctcgggtga ggcgacggac gtggcgcaga
    22021 aggcgttcgc ggcgggtggc ggcagctcgg tgttcgagtc gtccgctctg caacgttgcc
    22081 tgcgcgacgt gcacgtggcc gcgcagcaca cggtggtgtc gcgccggatg ctggagacgt
    22141 actcgatgct caagctggga ctcgctccgg acatgacgag gttctgatgg acgcgctcga
    22201 agcgatcatg accacgcggg cgatccgccg gttcaccgac gagcccgtcg ccgaggacga
    22261 cctgtggaca tgcctgcggg cggcccagca ggcgccgtcc ggcggcaacg tccagcccac
    22321 gcggtatctg gtggtcaccg atccggacgt gcgcgccgag gtgggcaagc tgtaccgcag
    22381 cgcgttcacc cgctacgccg agatggcgcc ggaacgcacc gacgccgtcg gcctgcgcat
    22441 cggccggtcc gcgaaccacc tcgccgacac actcgggtcc gtgccggtga tcgtgttctt
    22501 cctcatgccg cgcctgccgt cgctggtgga gggcatcgac atcgggccgg tgcacgcgtc
    22561 ggtctatccg gccgtgcaga acttctgcct ggcggcgcgc gcgttgg
//
