LOCUS       NZ_FOSG01000037        16975 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces pini strain PL19, whole genome shotgun sequence.
ACCESSION   NZ_FOSG01000037
VERSION     NZ_FOSG01000037.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces pini
  ORGANISM  Streptomyces pini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900114215.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:14:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,762
            CDSs (total)                      :: 5,677
            Genes (coding)                    :: 5,560
            CDSs (with protein)               :: 5,560
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 3, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 20 of 117
            Pseudo Genes (incomplete)         :: 111 of 117
            Pseudo Genes (internal stop)      :: 1 of 117
            Pseudo Genes (multiple problems)  :: 15 of 117
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 16975
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOSG01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..16975
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     gene            complement(<1..3479)
                     /locus_tag="BM237_RS28150"
                     /old_locus_tag="SAMN05192584_1371"
     CDS             complement(<1..3479)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (19-444). E-value:
                     3.2e-164. Score: 538.8. Matches aSDomain:
                     nrpspksdomains_BM237_RS28150_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (552-850). E-value: 6.1e-104.
                     Score: 339.5. Matches aSDomain:
                     nrpspksdomains_BM237_RS28150_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_PP (939-1025). E-value: 3e-26.
                     Score: 83.6. Matches aSDomain:
                     nrpspksdomains_BM237_RS28150_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144002.1"
                     /locus_tag="BM237_RS28150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1371"
                     /product="type I polyketide synthase"
                     /protein_id="WP_139238200.1"
                     /sec_met_domain="hyb_KS (E-value: 1.9e-170, bitscore:
                     556.4, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 8e-85, bitscore:
                     273.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.1e-105, bitscore:
                     339.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.5e-14, bitscore:
                     41.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3.2e-57, bitscore: 183.2,
                     seeds: 217, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQSRSDRSTPGAQTDEPIAVIGLSCRLPGASSPEEFWRLLRGG
                     TDAVTEVPPGRWGAGEPHTGDAPAPGAADIRRGGFVDGVDEFDAAFFGISPGEALAMDP
                     QQRLVLELAWEALEDARILPGSLDGSGTGIFVGAIWDDYARLLHEYGPGAVDHYTLTGL
                     QRGIIANRVSYALGLRGPSMTLDSAQSSSLVAVHTACAALRAGECDVAVAGGINLDLIP
                     ESALALARVGALSPGGRVRVLDAEADGTVRGEGGALAVLKPLSAALAAGDPVYCVIRGS
                     AVNNDGATDGLTAPGAETQSAVLRAACRRAGVDPTDLQYVELHGTGTPVGDPVEALALG
                     TVAGRGRPADSPLLVGSVKTNIGHLEGAAGVVGLLKVALGIRHRELPPTLHHHTPSPAV
                     PLDELRLRVQRELGPWPRQDVPLLAGVTSLGVGGTNCHVVLAEAPHRDREAEREAAHVP
                     ETPAAPLPWVLSGRTEAALRAQAARLADHLDSRPGTGPAEVGLALATTRTAFEHRAAVV
                     GTGRGELLAGLRALADGTPSTHTVSGTPAEGRLAVLFGGGGSQRAGMGRELYAAHPVYA
                     AAFDAVCEQLDRHLDRPVRELILAEPGSPEATLLDRTDYALPALLAVETALYRLYESWG
                     VTPDHLTGHSMGELTAAHVAGVLSLPDVCLLAVERARLIQSAAGGAMAAVQASEEEVLA
                     DLGRYADRVSVAAVNSPDGTVVSGDEDAVLDLCARWKARDRKTKRLAVTVAGHSPHMDG
                     ILDAFREVARSLSYAPARIPVVSNVTGRIATDEELTSPEYWVRHIRATVRFADGIRALS
                     DEGVTTFLELSPTPVLTQAVTTTLEGARPRPATVSALQQDRPEARTAVAALARLHTVGA
                     AWDPSAVFPPGTRPCDLPTYAFQRKRYWPAPAGRRRDGAPAGNGGLRGVASGTAAPDGD
                     SASGALRRRLADLPGAERERVLLDLVDAAVAVVLQRPGTEPADPGTPFRDLGFTSLRSV
                     ELRNHLETATGLRLPASLLFDHPTPEALVGRLLDELLGGSDGAAKELSSAPVAVAAVDE
                     PVAIVGIGCRFPGGVRGPEDLWRLVAEGRDAVSGFPENRGWDLEGLYDPDPESVGTSYT
                     RRGGFLHDADRFDAEFFGISPREALATDPQQRLLLETAWEALERAGIDPGSLR"
     source          1..16975
                     /db_xref="taxon:1520580"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0075229_137"
                     /organism="Streptomyces pini"
                     /strain="PL19"
                     /type_material="type strain of Streptomyces pini"
     cand_cluster    1..16975
                     /SMILES="CC(=O)NC(CO)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..16975
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[7634:14942](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(7635..14942)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..16975
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<0:3479](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(<1..3479)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     CDS_motif       complement(51..77)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0011"
                     /evalue="1.70E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="BM237_RS28150"
                     /protein_end="1143"
                     /protein_start="1134"
                     /score="8.2"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     aSDomain        complement(405..662)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28150_PKS_PP.1"
                     /evalue="3.00E-26"
                     /label="BM237_RS28150_PKS_PP.1"
                     /locus_tag="BM237_RS28150"
                     /protein_end="1025"
                     /protein_start="939"
                     /score="83.6"
                     /tool="antismash"
                     /translation="LADLPGAERERVLLDLVDAAVAVVLQRPGTEPADPGTPFRDLGFT
                     SLRSVELRNHLETATGLRLPASLLFDHPTPEALVGRLLDEL"
     aSModule        complement(405..3422)
                     /complete
                     /domains="nrpspksdomains_BM237_RS28150_PKS_KS.1"
                     /domains="nrpspksdomains_BM237_RS28150_PKS_AT.1"
                     /domains="nrpspksdomains_BM237_RS28150_PKS_PP.1"
                     /locus_tags="BM237_RS28150"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(930..1823)
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28150_PKS_AT.1"
                     /evalue="6.10E-104"
                     /label="BM237_RS28150_PKS_AT.1"
                     /locus_tag="BM237_RS28150"
                     /protein_end="850"
                     /protein_start="552"
                     /score="339.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFGGGGSQRAGMGRELYAAHPVYAAAFDAVCEQLDRHLDRPVREL
                     ILAEPGSPEATLLDRTDYALPALLAVETALYRLYESWGVTPDHLTGHSMGELTAAHVAG
                     VLSLPDVCLLAVERARLIQSAAGGAMAAVQASEEEVLADLGRYADRVSVAAVNSPDGTV
                     VSGDEDAVLDLCARWKARDRKTKRLAVTVAGHSPHMDGILDAFREVARSLSYAPARIPV
                     VSNVTGRIATDEELTSPEYWVRHIRATVRFADGIRALSDEGVTTFLELSPTPVLTQAVT
                     TTLEGARPRPATVSALQ"
     CDS_motif       complement(1068..1103)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0010"
                     /evalue="8.10E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="BM237_RS28150"
                     /protein_end="804"
                     /protein_start="792"
                     /score="15.9"
                     /tool="antismash"
                     /translation="YWVRHIRATVRF"
     CDS_motif       complement(1326..1364)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0009"
                     /evalue="5.60E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="BM237_RS28150"
                     /protein_end="718"
                     /protein_start="705"
                     /score="13.2"
                     /tool="antismash"
                     /translation="AAVNSPDGTVVSG"
     CDS_motif       complement(1455..1577)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0008"
                     /evalue="1.40E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="BM237_RS28150"
                     /protein_end="675"
                     /protein_start="634"
                     /score="59.0"
                     /tool="antismash"
                     /translation="GVTPDHLTGHSMGELTAAHVAGVLSLPDVCLLAVERARLIQ"
     CDS_motif       complement(1773..1823)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0007"
                     /evalue="6.60E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BM237_RS28150"
                     /protein_end="569"
                     /protein_start="552"
                     /score="12.5"
                     /tool="antismash"
                     /translation="LFGGGGSQRAGMGRELY"
     CDS_motif       complement(2067..2090)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0006"
                     /evalue="6.10E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="BM237_RS28150"
                     /protein_end="471"
                     /protein_start="463"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="PLPWVLSG"
     aSDomain        complement(2148..3422)
                     /ASF="found active site cysteine: False, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28150_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="3.20E-164"
                     /label="BM237_RS28150_PKS_KS.1"
                     /locus_tag="BM237_RS28150"
                     /protein_end="444"
                     /protein_start="19"
                     /score="538.8"
                     /tool="antismash"
                     /translation="IAVIGLSCRLPGASSPEEFWRLLRGGTDAVTEVPPGRWGAGEPHT
                     GDAPAPGAADIRRGGFVDGVDEFDAAFFGISPGEALAMDPQQRLVLELAWEALEDARIL
                     PGSLDGSGTGIFVGAIWDDYARLLHEYGPGAVDHYTLTGLQRGIIANRVSYALGLRGPS
                     MTLDSAQSSSLVAVHTACAALRAGECDVAVAGGINLDLIPESALALARVGALSPGGRVR
                     VLDAEADGTVRGEGGALAVLKPLSAALAAGDPVYCVIRGSAVNNDGATDGLTAPGAETQ
                     SAVLRAACRRAGVDPTDLQYVELHGTGTPVGDPVEALALGTVAGRGRPADSPLLVGSVK
                     TNIGHLEGAAGVVGLLKVALGIRHRELPPTLHHHTPSPAVPLDELRLRVQRELGPWPRQ
                     DVPLLAGVTSLGVGGTNCHVVLAEAP"
     CDS_motif       complement(2370..2414)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0005"
                     /evalue="3.50E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="BM237_RS28150"
                     /protein_end="370"
                     /protein_start="355"
                     /score="12.9"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEGAAG"
     CDS_motif       complement(2475..2522)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0004"
                     /evalue="2.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BM237_RS28150"
                     /protein_end="335"
                     /protein_start="319"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YVELHGTGTPVGDPVE"
     CDS_motif       complement(2715..2750)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0003"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="BM237_RS28150"
                     /protein_end="255"
                     /protein_start="243"
                     /score="11.2"
                     /tool="antismash"
                     /translation="DAEADGTVRGEG"
     CDS_motif       complement(2877..2942)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0002"
                     /evalue="4.90E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="BM237_RS28150"
                     /protein_end="201"
                     /protein_start="179"
                     /score="12.7"
                     /tool="antismash"
                     /translation="GPSMTLDSAQSSSLVAVHTACA"
     CDS_motif       complement(3147..3173)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28150_0001"
                     /evalue="3.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="BM237_RS28150"
                     /protein_end="111"
                     /protein_start="102"
                     /score="7.2"
                     /tool="antismash"
                     /translation="DPQQRLVLE"
     gene            complement(3592..4044)
                     /locus_tag="BM237_RS28155"
                     /old_locus_tag="SAMN05192584_1372"
     CDS             complement(3592..4044)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144001.1"
                     /locus_tag="BM237_RS28155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1372"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_093852571.1"
                     /transl_table=11
                     /translation="MSAVQPQELKRLFAHSLELLSQGKVEEWVGLFADDGVLEFPYPAP
                     GFPTTMRGRDELLAQMRMFAEQLRAEFSEPEFYAVTDDGLLVAAYTADCTLVATGGRYR
                     QTYLSVVRFENGAITLFRDFWNPWLVMEAAGGEVAWKQAIQALADR"
     misc_feature    3995..4010
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.43"
                     /tool="antismash"
     gene            complement(4148..5032)
                     /locus_tag="BM237_RS28160"
                     /old_locus_tag="SAMN05192584_1373"
     CDS             complement(4148..5032)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144000.1"
                     /locus_tag="BM237_RS28160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1373"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_093852572.1"
                     /transl_table=11
                     /translation="MSNRSGLLPPDGRAVVITGASSGLGESCALNLARVGFHVFAGVRR
                     AEDGERLRRAATGRLTPVTLDVTDEGSVGEAVREIGAHTGEDGLWGLVNNAGIAVTAPL
                     ECVGTELLRRQLDTNVVGQLAVIRGFLPLLRAGGGRIVNVTSGLGNVAIPYLGAYAAAQ
                     FAKEALSDALRRELAPQGITVCVVQPGAIMTPIWDKMSTEAGRTIEGAAAPLQELYRDT
                     FLRFVETNEQQARGSRKTPDDVARTVFRALVARRPRTRYGVGADATGGRLLARLLPDRA
                     VDRVFGSVVRPSR"
     gene            complement(5051..6439)
                     /locus_tag="BM237_RS28165"
                     /old_locus_tag="SAMN05192584_1374"
     CDS             complement(5051..6439)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (10-173). E-value:
                     4.8e-15. Score: 47.3. Matches aSDomain:
                     nrpspksdomains_BM237_RS28165_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF028221.4"
                     /locus_tag="BM237_RS28165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1374"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_093852573.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-17, bitscore:
                     52.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRPAAHTEAERPLSPLERWYWIVDQISPLNVISHARIHGGLSEE
                     LLAQALDALQQRHPMLRTAIRADAAGRGPRFTAAPGNPIPLRSVTAGAPGEATADDRWE
                     KEVNGHELVTPVDWSRGPLARAVVISTSGAEPGEQDVHDLLLTLPHCIADGTTVLTLMR
                     QWIELAAEIEAGDLDPDGLTVWSERVLPAPEGMLPPDHRGLSGLRRIAAQQLTDQGVAR
                     RLKPRRMEATRRVPFRERTTRLLHRSLSADQLADLAEACRREQTTVHGALAAAMVRAVA
                     EDAGAGPGPVMIGSPITFRDALVPRVTDREIGTYVATVPTVVDYRPDASLWPMARTVSR
                     DLVRRRQRGEHLTAVATLGLVSPKSVDKSARFLRFMEEKGPITLCISNIGRYDFPGSVG
                     PWRVSSAQFIAGLSVNALYCATVNTSHGRMAWNFTHVEGAVPADRAERIAAGSVDAVLA
                     ASKS"
     CDS_motif       complement(5585..5614)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28165_0002"
                     /evalue="9.90E+01"
                     /label="Cy2"
                     /locus_tag="BM237_RS28165"
                     /protein_end="285"
                     /protein_start="275"
                     /score="-3.8"
                     /tool="antismash"
                     /translation="MVRAVAEDAG"
     aSDomain        complement(5921..6409)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28165_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.80E-15"
                     /label="BM237_RS28165_Condensation_LCL.1"
                     /locus_tag="BM237_RS28165"
                     /protein_end="173"
                     /protein_start="10"
                     /score="47.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: PHCIADG"
                     /tool="antismash"
                     /translation="ERPLSPLERWYWIVDQISPLNVISHARIHGGLSEELLAQALDALQ
                     QRHPMLRTAIRADAAGRGPRFTAAPGNPIPLRSVTAGAPGEATADDRWEKEVNGHELVT
                     PVDWSRGPLARAVVISTSGAEPGEQDVHDLLLTLPHCIADGTTVLTLMRQWIELAAEIE
                     "
     CDS_motif       complement(6245..6334)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28165_0001"
                     /evalue="1.10E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="BM237_RS28165"
                     /protein_end="65"
                     /protein_start="35"
                     /score="30.6"
                     /tool="antismash"
                     /translation="ARIHGGLSEELLAQALDALQQRHPMLRTAI"
     gene            complement(6436..7638)
                     /locus_tag="BM237_RS28170"
                     /old_locus_tag="SAMN05192584_1375"
     CDS             complement(6436..7638)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143998.1"
                     /locus_tag="BM237_RS28170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1375"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_093852574.1"
                     /transl_table=11
                     /translation="MTTGRNGKAIVVGAGIGGLAAAACLRRVGMDVEVYERARELRPAG
                     GALSFMTNAVVALRTLGIDLRLEENAEILEELHFLTARGKVIRTLRFKEICDRLGAPSF
                     GVTRTLLQRLLLEQVGDCPVVLGAAATGFTPDGDGVRVHFEDGREARGDVLIGADGFGS
                     AVRRQIAGPETPRETGYLCWVATPEFTHPRVTKQYGAHYWGRGRRFGLANIGGGRVYWW
                     GTKNMPAERARDWDGDKDEIVRAYAGWADEVQAAVAATPFEQITAFPARDRPFLESWGR
                     GPVTLLGDAAHPMMTSLGQGACMAVEDAVVLAHHLAREPGSPQRALRAYEAERRPRTRR
                     IVEGAHALSGLEQTESPLRLMGRNLFFRLAPSSVLDKQNAEYLDFPGTRATDDHTMEVQ
                     P"
     gene            complement(7635..14942)
                     /locus_tag="BM237_RS28175"
                     /old_locus_tag="SAMN05192584_1376"
     CDS             complement(7635..14942)
                     /NRPS_PKS="Domain: Condensation_Starter (17-300). E-value:
                     9.1e-75. Score: 243.7. Matches aSDomain:
                     nrpspksdomains_BM237_RS28175_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (464-869). E-value:
                     6.3e-117. Score: 382.5. Matches aSDomain:
                     nrpspksdomains_BM237_RS28175_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (978-1044). E-value: 3e-20. Score:
                     64.2. Matches aSDomain: nrpspksdomains_BM237_RS28175_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1074-1374). E-value:
                     7e-51. Score: 165.0. Matches aSDomain:
                     nrpspksdomains_BM237_RS28175_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1527-1944). E-value:
                     1.4e-88. Score: 289.2. Matches aSDomain:
                     nrpspksdomains_BM237_RS28175_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2057-2125). E-value: 1.8e-19.
                     Score: 61.7. Matches aSDomain:
                     nrpspksdomains_BM237_RS28175_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2145-2398). E-value:
                     1.1e-40. Score: 132.5. Matches aSDomain:
                     nrpspksdomains_BM237_RS28175_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982262.1"
                     /locus_tag="BM237_RS28175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1376"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_342746270.1"
                     /sec_met_domain="Condensation (E-value: 2.7e-45, bitscore:
                     143.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-121, bitscore:
                     394.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.6e-17, bitscore:
                     51.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 4.8e-36, bitscore:
                     114.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSEATRVEDILNSFEWAPLTAYQRDIWVANALFPKLPQFNLFVS
                     QRLTGPVDTDRLAACLLEAVRRNDALRLRFTEEDGTPLQRVDSSDGPQVRMLDFTGEPD
                     PRAACEAWMAESFGRPLSLTGGPAYELAVLKESGTAAHAYVKAHHILTDAWGLNLLLEQ
                     VRAHYAGEADDAPAPSCLAALEDEERYRNSPQYGRDRDHFRTALAGAVPPLFTRRAPSG
                     SRGSGRHSFGLPREAAERIRERGQSPFAFVTAAFAAYLSRVHLADDVVIGVPLFNRRGR
                     TQRRTVGHFANTLPLRVPVAKAATFAELVAAVQAGSRELQRHERLPLGDVLRDLPPGSP
                     RELFDVTVSYVQWPSPREIPGLRQEFAGGTRAHDGDALAVVVAETAGTGDITVELDYAR
                     DVFDEDFPAAALGRHIRNLVLDALRDPDRPVGAIGMLDPDEREEIVHGLNRTAVDYPAD
                     RTLHGLFEEQAARTPDRTAVVGPGSGDALTYAELDARAGRLARALRADGVEPGDRVAVA
                     LERSTSTLVAVLAVLKAGAAYVPVDPAHPAERIRLLLEDSGARAILTGPGTPAPPRGPA
                     VVRRADEPLTGPFGPLPDSGGPHDLAYVLYTSGSTGRPKGVMVEHRSVVNRLTWMQRRY
                     AVGDGDVLLQKTPISFDVSVWELFWWGLAGARLALLAPGAEKDPRETLRTIGERGVTVV
                     HFVPSMFGPFLDLLESRPELRAEAGSLRRVFCSGEALPPEQVNRFNRLLGPAGTRLVNL
                     YGPTEATVDVSFHDCPGDPSRPVGRVPIGRPIDNIRLHVLDRHGNPQPAGAPGELCVAG
                     DGVARGYLGRPELTARKFTDDPFTPGGRLYRTGDLARRLADGELEYLGRMDGQVKVRGN
                     RVELGEVEHRLSRVPGVRGAVVVDTVDEDRSVRLAGCYVADRDLDAAGLRAALAQSLPD
                     YMIPARYVRVDRIPLTPNGKADRGALRRLLPAEAGRGAGSGQAPRNATEAALAEIWSKV
                     LGVEQVGPHDDYFALGGDSILMLRVRAEAEKRGLRVTLPDLARHTTVAELAARVTPATA
                     DDGEAAPEPFALVPGVDRARLLGTGAEDAYPATRLHLGMLYHSSEEKTSTVYRDVFHYR
                     LACAWDEPAFRAAADRLVARHPALRSSFALAGHSEPLQIVHPRVTGVLSVADLRGTDGT
                     AAEKALREHIEERRHHAYDHERPGLYHLHAHVRDGGRLDLVLSFHHAILDGWSVAGLMS
                     ELLRDYLHGLGADVAPVPDAALPSPALHVRDERRLLESRESREYWRDLLDGAEPVQLDP
                     FVPYEPSPGEESVVRHVELPADLDEALKGFARGHALPLRLVLFTAHCLTLRLLADTDDV
                     TTGLVTHGRPETEGADRIAGLFLNTMPFRLRPGQESWLETVRDVVRQERDSHPHRAYPL
                     SAVQDDRGGAPLLDSAFTFVRLHTLEELFARADLELLDLTTYEETNFALLVNAIVDPRD
                     GRTRLRLNCAGRSFTATQADLLADTYTAILRRIVEHPEEAPDFHFLVESDELPTNPAAE
                     PADVMSLFAATAARQPDAEAVVHGGTRWTYAELERAARQVTRRLHELGVEPGAGVGIAL
                     DRSPEMIATVIGVLRAKAACVPLDVSYPPERIARMVERARPFRVVAHERHAGLVPDPGL
                     VLPVESIPMPGPDGGAEPAGERETGTPETGERETGALPLDSLALILFTSGSSGEPKGVE
                     LPHRLWANYTQWQLRAETAAPGARTLQFAPLSFDVSFQEIFSTLAAGGTLHLVSEPDRR
                     DPSALLRLMDEQEIERWFMPFVALQQIAEASQLLGVRPRALRVLISSGEQLRVTEEVRR
                     FCAARPGTLLENQYGPTETNIASAHLLSGDPAGWPALPPIGTAIDGAEIHVLDSRLRPV
                     PAGVRGEIYLGGACLALGYRGRPDLTEERFVPHPCGKPGVRLYRTGDLGRVLPGGDTVW
                     LGRADNQVKVRGFRVEPAEIEIALTAMSDDFPGIRGAAVVARGRGDGLDSFLVAFLLGE
                     EGSADLEEVRKRLRAVLPEYMVPAHLAWLPRLPLTPSGKRDDAALRRIPLETRREAGSA
                     PPRNAHERALTDIFGEMLGRPGFGIHDDFFESGGTSLTAMRLIVTIEKRFGVRVPLTAF
                     VAAPTVARLAELLRTGDAAAAFDPVVPIRSGGSRPPLFLVHPLGGNVLCYVRLARHLPD
                     DQPLYALQAAGAEPGTEPVATMEGLAGSYLEAIRRVQPEGPYHLGGWSFGGFVAFEMAR
                     QLKRSGRDEVASLILLDSIAPSPGERPDVAERAMMEWFFWELIWVDRGGSAPVERIPDE
                     LGTDDERLDFIAERAARAGIVSARGARSAVRRLFEVYKANWASLRDYQPAPDPVDVTLI
                     KATAPLPDVLRPMHGAARTLHDAPANGWATLTSGRLDVVDVSGDHLLLLDEPHVRSVGR
                     AVAGAMAAGTEEPDGRTGREPVLTDEGAAQ"
     aSDomain        complement(7749..8507)
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28175_Thioesterase.1"
                     /evalue="1.10E-40"
                     /label="BM237_RS28175_Thioesterase.1"
                     /locus_tag="BM237_RS28175"
                     /protein_end="2398"
                     /protein_start="2145"
                     /score="132.5"
                     /tool="antismash"
                     /translation="PLFLVHPLGGNVLCYVRLARHLPDDQPLYALQAAGAEPGTEPVAT
                     MEGLAGSYLEAIRRVQPEGPYHLGGWSFGGFVAFEMARQLKRSGRDEVASLILLDSIAP
                     SPGERPDVAERAMMEWFFWELIWVDRGGSAPVERIPDELGTDDERLDFIAERAARAGIV
                     SARGARSAVRRLFEVYKANWASLRDYQPAPDPVDVTLIKATAPLPDVLRPMHGAARTLH
                     DAPANGWATLTSGRLDVVDVSGDHLLLLDEP"
     aSModule        complement(7749..11720)
                     /complete
                     /domains="nrpspksdomains_BM237_RS28175_Condensation_DCL.1"
                     /domains="nrpspksdomains_BM237_RS28175_AMP-binding.2"
                     /domains="nrpspksdomains_BM237_RS28175_PCP.2"
                     /domains="nrpspksdomains_BM237_RS28175_Thioesterase.1"
                     /final_module
                     /locus_tags="BM237_RS28175"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(8253..8327)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0018"
                     /evalue="5.10E-17"
                     /label="NRPS-te1"
                     /locus_tag="BM237_RS28175"
                     /protein_end="2230"
                     /protein_start="2205"
                     /score="54.0"
                     /tool="antismash"
                     /translation="QPEGPYHLGGWSFGGFVAFEMARQL"
     aSDomain        complement(8568..8771)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28175_PCP.2"
                     /evalue="1.80E-19"
                     /label="BM237_RS28175_PCP.2"
                     /locus_tag="BM237_RS28175"
                     /protein_end="2125"
                     /protein_start="2057"
                     /score="61.7"
                     /tool="antismash"
                     /translation="ERALTDIFGEMLGRPGFGIHDDFFESGGTSLTAMRLIVTIEKRFG
                     VRVPLTAFVAAPTVARLAELLRT"
     CDS_motif       complement(9081..9146)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0017"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1954"
                     /protein_start="1932"
                     /score="34.8"
                     /tool="antismash"
                     /translation="WLGRADNQVKVRGFRVEPAEIE"
     aSDomain        complement(9111..10361)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28175_AMP-binding.2"
                     /evalue="1.40E-88"
                     /label="BM237_RS28175_AMP-binding.2"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1944"
                     /protein_start="1527"
                     /score="289.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FAATAARQPDAEAVVHGGTRWTYAELERAARQVTRRLHELGVEPG
                     AGVGIALDRSPEMIATVIGVLRAKAACVPLDVSYPPERIARMVERARPFRVVAHERHAG
                     LVPDPGLVLPVESIPMPGPDGGAEPAGERETGTPETGERETGALPLDSLALILFTSGSS
                     GEPKGVELPHRLWANYTQWQLRAETAAPGARTLQFAPLSFDVSFQEIFSTLAAGGTLHL
                     VSEPDRRDPSALLRLMDEQEIERWFMPFVALQQIAEASQLLGVRPRALRVLISSGEQLR
                     VTEEVRRFCAARPGTLLENQYGPTETNIASAHLLSGDPAGWPALPPIGTAIDGAEIHVL
                     DSRLRPVPAGVRGEIYLGGACLALGYRGRPDLTEERFVPHPCGKPGVRLYRTGDLGRVL
                     PGGDTVWLGRADNQVKVR"
     CDS_motif       complement(9231..9320)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0016"
                     /evalue="3.90E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1904"
                     /protein_start="1874"
                     /score="41.5"
                     /tool="antismash"
                     /translation="PAGVRGEIYLGGACLALGYRGRPDLTEERF"
     CDS_motif       complement(9432..9461)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0015"
                     /evalue="1.40E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1837"
                     /protein_start="1827"
                     /score="5.5"
                     /tool="antismash"
                     /translation="QYGPTETNIA"
     CDS_motif       complement(9843..9902)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0014"
                     /evalue="1.60E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1700"
                     /protein_start="1680"
                     /score="20.7"
                     /tool="antismash"
                     /translation="ALILFTSGSSGEPKGVELPH"
     CDS_motif       complement(10134..10172)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0013"
                     /evalue="1.50E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1603"
                     /protein_start="1590"
                     /score="9.1"
                     /tool="antismash"
                     /translation="GVLRAKAACVPLD"
     aSDomain        complement(10821..11720)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28175_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="7.00E-51"
                     /label="BM237_RS28175_Condensation_DCL.1"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1374"
                     /protein_start="1074"
                     /score="165.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAILDG"
                     /tool="antismash"
                     /translation="EDAYPATRLHLGMLYHSSEEKTSTVYRDVFHYRLACAWDEPAFRA
                     AADRLVARHPALRSSFALAGHSEPLQIVHPRVTGVLSVADLRGTDGTAAEKALREHIEE
                     RRHHAYDHERPGLYHLHAHVRDGGRLDLVLSFHHAILDGWSVAGLMSELLRDYLHGLGA
                     DVAPVPDAALPSPALHVRDERRLLESRESREYWRDLLDGAEPVQLDPFVPYEPSPGEES
                     VVRHVELPADLDEALKGFARGHALPLRLVLFTAHCLTLRLLADTDDVTTGLVTHGRPET
                     EGADRIAGLFLNTMPFRLR"
     CDS_motif       complement(10827..10919)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0012"
                     /evalue="8.10E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1372"
                     /protein_start="1341"
                     /score="18.3"
                     /tool="antismash"
                     /translation="DVTTGLVTHGRPETEGADRIAGLFLNTMPFR"
     CDS_motif       complement(11259..11315)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0011"
                     /evalue="8.80E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1228"
                     /protein_start="1209"
                     /score="21.5"
                     /tool="antismash"
                     /translation="FHHAILDGWSVAGLMSELL"
     CDS_motif       complement(11538..11648)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0010"
                     /evalue="2.50E-10"
                     /label="C2_DCL_024-062"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1135"
                     /protein_start="1098"
                     /score="32.6"
                     /tool="antismash"
                     /translation="VYRDVFHYRLACAWDEPAFRAAADRLVARHPALRSSF"
     aSDomain        complement(11811..12008)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28175_PCP.1"
                     /evalue="3.00E-20"
                     /label="BM237_RS28175_PCP.1"
                     /locus_tag="BM237_RS28175"
                     /protein_end="1044"
                     /protein_start="978"
                     /score="64.2"
                     /tool="antismash"
                     /translation="EAALAEIWSKVLGVEQVGPHDDYFALGGDSILMLRVRAEAEKRGL
                     RVTLPDLARHTTVAELAARVT"
     aSModule        complement(11811..14891)
                     /complete
                     /domains="nrpspksdomains_BM237_RS28175_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_BM237_RS28175_AMP-binding.1"
                     /domains="nrpspksdomains_BM237_RS28175_PCP.1"
                     /locus_tags="BM237_RS28175"
                     /monomer_pairings="Ser -> Ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(12306..12371)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0009"
                     /evalue="9.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="BM237_RS28175"
                     /protein_end="879"
                     /protein_start="857"
                     /score="33.8"
                     /tool="antismash"
                     /translation="YLGRMDGQVKVRGNRVELGEVE"
     aSDomain        complement(12336..13550)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28175_AMP-binding.1"
                     /evalue="6.30E-117"
                     /label="BM237_RS28175_AMP-binding.1"
                     /locus_tag="BM237_RS28175"
                     /protein_end="869"
                     /protein_start="464"
                     /score="382.5"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="FEEQAARTPDRTAVVGPGSGDALTYAELDARAGRLARALRADGVE
                     PGDRVAVALERSTSTLVAVLAVLKAGAAYVPVDPAHPAERIRLLLEDSGARAILTGPGT
                     PAPPRGPAVVRRADEPLTGPFGPLPDSGGPHDLAYVLYTSGSTGRPKGVMVEHRSVVNR
                     LTWMQRRYAVGDGDVLLQKTPISFDVSVWELFWWGLAGARLALLAPGAEKDPRETLRTI
                     GERGVTVVHFVPSMFGPFLDLLESRPELRAEAGSLRRVFCSGEALPPEQVNRFNRLLGP
                     AGTRLVNLYGPTEATVDVSFHDCPGDPSRPVGRVPIGRPIDNIRLHVLDRHGNPQPAGA
                     PGELCVAGDGVARGYLGRPELTARKFTDDPFTPGGRLYRTGDLARRLADGELEYLGRMD
                     GQVKVR"
     CDS_motif       complement(12453..12542)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0008"
                     /evalue="5.90E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="BM237_RS28175"
                     /protein_end="830"
                     /protein_start="800"
                     /score="53.7"
                     /tool="antismash"
                     /translation="PAGAPGELCVAGDGVARGYLGRPELTARKF"
     CDS_motif       complement(12660..12683)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0007"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="BM237_RS28175"
                     /protein_end="761"
                     /protein_start="753"
                     /score="5.7"
                     /tool="antismash"
                     /translation="YGPTEATV"
     CDS_motif       complement(13080..13139)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0006"
                     /evalue="3.80E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="BM237_RS28175"
                     /protein_end="621"
                     /protein_start="601"
                     /score="34.7"
                     /tool="antismash"
                     /translation="AYVLYTSGSTGRPKGVMVEH"
     CDS_motif       complement(13317..13358)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0005"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="BM237_RS28175"
                     /protein_end="542"
                     /protein_start="528"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LAVLKAGAAYVPVD"
     CDS_motif       complement(13788..13826)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0004"
                     /evalue="1.10E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="BM237_RS28175"
                     /protein_end="385"
                     /protein_start="372"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="HDGDALAVVVAET"
     aSDomain        complement(14043..14891)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS28175_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="9.10E-75"
                     /label="BM237_RS28175_Condensation_Starter.1"
                     /locus_tag="BM237_RS28175"
                     /protein_end="300"
                     /protein_start="17"
                     /score="243.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILTDA"
                     /tool="antismash"
                     /translation="APLTAYQRDIWVANALFPKLPQFNLFVSQRLTGPVDTDRLAACLL
                     EAVRRNDALRLRFTEEDGTPLQRVDSSDGPQVRMLDFTGEPDPRAACEAWMAESFGRPL
                     SLTGGPAYELAVLKESGTAAHAYVKAHHILTDAWGLNLLLEQVRAHYAGEADDAPAPSC
                     LAALEDEERYRNSPQYGRDRDHFRTALAGAVPPLFTRRAPSGSRGSGRHSFGLPREAAE
                     RIRERGQSPFAFVTAAFAAYLSRVHLADDVVIGVPLFNRRGRTQRRTVGHFANTLPLRV
                     PV"
     CDS_motif       complement(14052..14141)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0003"
                     /evalue="2.60E-12"
                     /label="C5_starter_265-294"
                     /locus_tag="BM237_RS28175"
                     /protein_end="297"
                     /protein_start="267"
                     /score="39.0"
                     /tool="antismash"
                     /translation="DVVIGVPLFNRRGRTQRRTVGHFANTLPLR"
     CDS_motif       complement(14439..14504)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0002"
                     /evalue="4.10E-06"
                     /label="C3_starter_134-155"
                     /locus_tag="BM237_RS28175"
                     /protein_end="168"
                     /protein_start="146"
                     /score="19.7"
                     /tool="antismash"
                     /translation="AHHILTDAWGLNLLLEQVRAHY"
     CDS_motif       complement(14712..14831)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS28175_0001"
                     /evalue="6.30E-09"
                     /label="C2_starter_024-063"
                     /locus_tag="BM237_RS28175"
                     /protein_end="77"
                     /protein_start="37"
                     /score="28.5"
                     /tool="antismash"
                     /translation="PQFNLFVSQRLTGPVDTDRLAACLLEAVRRNDALRLRFTE"
     gene            15179..16567
                     /locus_tag="BM237_RS28180"
                     /old_locus_tag="SAMN05192584_1377"
     CDS             15179..16567
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143996.1"
                     /locus_tag="BM237_RS28180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1377"
                     /product="cytochrome P450"
                     /protein_id="WP_093852576.1"
                     /sec_met_domain="p450 (E-value: 1.1e-82, bitscore: 267.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQVPLVAAHPVLGSLRDLRHDTLGAYLRARRDHGDVVRFDAGP
                     PGLRASLYAVFSPEGVQQVLGSQASNFRKENDVYTEIRESIGNGLLTSQDEDYIRQRRM
                     IQPLFTRRRVDAYASAVYGEAVATADRWNSLSEKVVDAAEEMAEFALRTVTRVLFGADI
                     DAAADVVRRNFPVIGESVLRRGVTPLRLPRHWPTPANRRTQAAQRELYAICDRIIAERS
                     ATPGEADDMISRLILARDEDGSALSPDAIRDQVLVFLLAGHETTATALAFALHLLACHP
                     EAQEKAHAEVDAVLSGGTAGAEHLDELPYLTRVFKEALRMYPSVAIMGRRSVADSEVCG
                     FHIPGGSDVYVSPWVTQRHPGHWEHPDRFDPDRFAPELEAARPRYAWFPFGGGPRACIG
                     QYFAMLEGVIGLAGLLQRFRLTAPKTEIALQLGMTLRAAEPAHVRLTPRDGARGRVPRR
                     AGTE"
     gene            16564..>16975
                     /locus_tag="BM237_RS28185"
                     /old_locus_tag="SAMN05192584_1378"
                     /pseudo=""
     CDS             16564..>16975
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470664.1"
                     /locus_tag="BM237_RS28185"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_1378"
                     /product="crotonyl-CoA carboxylase/reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MREILDAILASDSKPADFANLALPESYRAVTVHKDEADMFAGMPT
                     RQKDPRKSLHLDQVPLPELGPGEALVAVMASSVNYNSVWTSIFEPVPTFGFLERYGRTS
                     PLARRHDLPYHIIGSDLAGVVLRTGPGVNAWQP"
ORIGIN
        1 cgcagcgacc ccggatcgat ccccgcccgc tccagcgcct cccacgccgt ctccagcagc
       61 aaccgctgct gcggatcggt cgccagcgcc tcccgcggcg agatcccgaa gaactccgcg
      121 tcgaaccggt ccgcatcatg caaaaacccg ccccgccgcg tatacgacgt ccccacactc
      181 tccggatccg ggtcgtacaa cccctccaga tcccaccccc ggttctccgg aaaccccgag
      241 accgcgtccc gaccctcggc caccagacgc cacagatcct ccggaccccg caccccaccc
      301 gggaaccgac acccgatccc cacgatcgcc accggctcgt ccaccgccgc caccgccacc
      361 ggcgccgagg acagctcctt cgcggccccg tccgatccgc ccagcagctc gtcgaggagc
      421 cggccgacca gggcctcggg ggtggggtgg tcgaacagca gggaggcggg caggcgcagg
      481 ccggtggcgg tctccaggtg gttgcgcagt tcgaccgagc gcagcgaggt gaagcccagg
      541 tccctgaagg gcgtgccggg gtccgccggt tccgtgccgg gccgctggag gacgaccgcg
      601 acggcggcgt ccaccaggtc cagcaggacg cgttcccgtt cggcgccggg caggtcggcc
      661 agtcgccgcc gcagcgcccc ggaggcgctg tcgccgtccg gcgccgcggt cccggacgcg
      721 acgcccctga gcccgccgtt tccggccggt gcgccgtcgc ggcgccggcc ggccggggcg
      781 ggccagtagc gcttgcgctg gaaggcgtag gtgggcaggt cgcacgggcg ggtgccgggc
      841 gggaagacgg cggacgggtc ccaggcggcg cccaccgtgt gcagccgtgc gagggcggcc
      901 acggcggtcc gggcctcggg gcggtcctgc tggagggcgg agaccgtggc cggacggggc
      961 cgggcgcctt cgagggtggt ggtgacggcc tgggtgagga caggggtcgg ggacagctcc
     1021 aggaacgtgg tgacgccctc gtcgctcagg gcccggatgc cgtcggcgaa gcggacggtg
     1081 gccctgatgt gccgcaccca gtactcgggg gaggtgagct cctcgtcggt ggcgatccgc
     1141 ccggtcacgt tcgacaccac cgggatgcgg gccggtgcgt acgacaggct ccgggcgacc
     1201 tcgcggaagg cgtcgaggat gccgtccatg tgcggggagt ggcccgcgac ggtgacggcc
     1261 aggcgcttgg tcttgcggtc ccgggccttc caccgggcgc acaggtcgag cacggcgtcc
     1321 tcgtcgccgg agacgaccgt gccgtcgggc gagttgaccg ccgcgaccga gacgcggtcc
     1381 gcgtaccggc cgaggtcggc gaggacctcc tcctcgctcg cctggacggc ggccatggcg
     1441 cccccggcgg cggactggat gagccgggcc cgctcgacgg ccagcaggca cacgtcgggc
     1501 agggacagca cccccgcgac gtgggcggcg gtgagttcgc ccatggagtg gccggtgagg
     1561 tggtcggggg tcacgcccca gctctcgtag agccggtaca gggcggtctc gacggcgagg
     1621 agggcgggca gcgcgtagtc ggtgcggtcg agcagggtgg cctcggggga gccgggctcg
     1681 gcgaggatca gttcccgcac gggccggtcg aggtgccggt cgagctgctc gcagacggcg
     1741 tcgaaggccg ccgcgtacac cgggtgggcc gcgtacagct cgcgtcccat gcccgcgcgc
     1801 tggctgccgc ccccgccgaa gaggacggcg aggcgtcctt cggccggggt gccggagacg
     1861 gtgtgggtcg acggtgtgcc gtcggccagg gcccgcagtc cggccaggag ttcgccgcgg
     1921 ccggtgccga ccacggcggc acggtgctcg aaggccgtgc gggtggtggc gagggcgagt
     1981 cccacctccg cggggccggt tccgggccgg gagtcgaggt ggtcggccag gcgggccgcc
     2041 tgggcccgca gggcggcttc cgtacggccg gagagcaccc agggcagagg ggcggcgggg
     2101 gtttccggca catgcgccgc ctcccgttcc gcctcccggt cccggtgcgg tgcctcggcg
     2161 agcaccacgt ggcagttggt gccgcccacg cccagcgagg tgacgccggc gagcagcggg
     2221 acgtcctgcc gcggccaggg gccgagttcc cgctggacgc gcagccgcag ttcgtccagg
     2281 gggacggcgg ggctgggggt gtggtggtgg agggtgggcg ggagttcccg gtgccggatg
     2341 ccgagggcga ccttgagcag gcccacgacg cccgcggcgc cctccaggtg gccgatgttc
     2401 gtcttgaccg agcccaccag cagcggcgag tccgccgggc ggccccggcc ggcgacggtc
     2461 cccagggcca gggcctcgac cgggtcgccc acgggggtgc cggtgccgtg cagttcgacg
     2521 tactggaggt cggtggggtc gactccggcg cggcggcagg ccgcgcggag cacggcgctc
     2581 tgcgtctcgg cgccgggggc ggtcagaccg tccgtggcgc cgtcgttgtt cacggcgctg
     2641 ccccggatca cgcagtacac ggggtcgccc gcggcgaggg ctgcggagag cggcttgagg
     2701 acggccagcg cgccgccctc accgcgcacg gtcccgtcgg cctccgcgtc caggacgcgg
     2761 acgcggccgc cgggcgagag cgcgccgacc cgggcgaggg cgagggcgct ctcgggtatg
     2821 aggtcgaggt tgatcccgcc ggcgacggcc acgtcgcact ccccggcgcg cagggcggcg
     2881 caggcggtgt gcacggcgac cagggaggag gactgggcgc tgtcgagggt catgctgggg
     2941 ccgcgcagtc cgagcgcgta cgacacccgg ttggcgatga tgccgcgctg gaggccggtg
     3001 agggtgtagt ggtcgacggc gccgggtccg tactcgtgca gcaggcgcgc gtagtcgtcc
     3061 cagatggcgc cgacgaagat gccggtgccg ctgccgtcga ggctgccggg gaggatccgg
     3121 gcgtcctcca gggcctccca ggccagttcg agcaccaggc gctgctgcgg gtccatggcg
     3181 agggcctcgc cgggcgagat gccgaagaag gccgcgtcga actcgtcgac gccgtcgacg
     3241 aagccgcccc ggcggatgtc ggccgcgccg ggggcggggg cgtccccggt gtgcggctcc
     3301 ccggcccccc agcgtccggg cggcacctct gtgaccgcgt cggtgccgcc gcgcagcagc
     3361 cgccagaact cctcggggct gctcgctccg ggcagtctgc acgacaggcc gatcacggcg
     3421 atcggctcgt ccgtctgcgc acccggcgtg ctgcggtcgc tgcggctctg ctcggtcata
     3481 gggtgcccgt ccctcgtggt gtgtgtgcgt gggaagccgt gggcccggca ccgtcgcggg
     3541 gtgccgggcg tgtcgggggc cggcggtcgg gagtggctcc cgccgcggag gtcagcggtc
     3601 ggcgagtgcc tggatggcct gcttccaggc gacctcgccg ccggccgcct ccatcacgag
     3661 ccaggggttc cagaagtcgc ggaagagcgt gatcgctccg ttctcgaagc gcaccacgga
     3721 caggtacgtc tggcggtacc ggccgccggt ggcgaccagg gtgcagtcgg cggtgtaggc
     3781 ggcgacgagc aggccgtcgt cggtcaccgc gtagaactcc ggctcggaga attcggcccg
     3841 gagctgctcg gcgaacatcc gcatctgggc gaggagttcg tccctgccgc gcatcgtggt
     3901 ggggaagccg ggcgccgggt aggggaactc gaggacgccg tcgtcggcga acaggccgac
     3961 ccactcctcg accttcccct gcgacagcaa ctccaggctg tgggcgaaca gtcgcttcag
     4021 ctcctgtggc tggactgcgg acatgtcgtc tctctttctg cgggctccgc acgggatgcg
     4081 ggatgccccg cggtttcgga cgcggtttcg gacgcggttt cggacggggg ttacgggggg
     4141 ggtggggtca gcgggagggc cggacgacgg agccgaagac gcggtcgacg gcccggtcgg
     4201 gcagcagccg ggccagcagg cgcccgccgg tcgcgtcggc gccgacgccg taacgggtcc
     4261 tgggacgcct ggcgacgagg gcgcggaaga cggtccgggc gacgtcgtcg ggggtcttgc
     4321 ggctgccgcg ggcctgctgc tcgttcgtct cgacgaagcg gaggaaggtg tcccggtaca
     4381 gctcctggag cggtgcggcg gcgccctcga tcgtcctgcc ggcctcggtg gacatcttgt
     4441 cccagatcgg ggtcatgatc gcaccgggct ggacgacgca gaccgtgatc ccctgagggg
     4501 cgagctcgcg gcgcagggcg tcgctgaggg cctccttggc gaactgggcg gcggcgtagg
     4561 ccccgaggta ggggatggcg acgttcccca ggcccgaggt cacgttcacg atgcgcccgc
     4621 cgccggcgcg cagcagcggc aggaagcccc ggatgacggc gagctggccg acgacgttgg
     4681 tgtcgagctg gcggcgcagc agctcggtgc cgacgcactc caggggtgcg gtgacggcga
     4741 tgcccgcgtt gttgaccagg ccccacaggc cgtcctcacc ggtgtgcgcg ccgatctcgc
     4801 gcacggcctc gccgaccgag ccctcgtccg tcacgtcgag cgtcaccggg gtcagccggc
     4861 cggtcgccgc gcggcgcagc cgctcgccgt cctcggcgcg ccggaccccg gcgaagacgt
     4921 ggaagcccac gcgggccagg ttcagcgcgc aggactcccc cagccccgag gaggctccgg
     4981 taatgacgac ggcccgcccg tcggggggca gcagacccga cctgttcgac acgtgttcct
     5041 ccgagttctc tcaggacttg ctcgccgcca ggaccgcgtc gacggatccg gcggctatcc
     5101 gctccgcccg gtccgccggc acggctccct cgacgtgggt gaagttccag gccatccgcc
     5161 cgtggctggt gttgaccgtc gcgcagtaca gggcgttgac ggacagtccg gcgatgaact
     5221 gggcggacga gacccgccac ggtccgacgc tgccggggaa gtcgtagcgg ccgatgttgg
     5281 agatgcagag ggtgatcggg cccttctcct ccatgaagcg gaggaacctg gcgcttttgt
     5341 ccaccgactt cggcgacacc aggcccaggg tcgcgacggc ggtcaggtgc tcgccgcgct
     5401 ggcggcgccg taccaggtcc cggctgacgg tccgcgccat cggccacagg gaggcgtccg
     5461 gccggtagtc gacgacggtg ggcacggtcg ccacgtaggt gccgatctcc cggtcggtca
     5521 cccgggggac gagcgcgtcg cggaaggtga tgggggagcc gatcatcacg gggcccggcc
     5581 cggcgccggc gtcctcggcg acggcgcgga ccatggccgc cgccagtgcg ccgtgcaccg
     5641 tggtctgctc cctgcggcac gcctccgcga ggtcggccag ctggtcggcg gagagcgagc
     5701 ggtgcaggag ccgggtggtg cgttcccgga acggcacccg ccgggtggcc tccatccggc
     5761 gcggcttcag ccggcgcgcg acaccctggt cggtcagctg ctgggcggcg atccggcgca
     5821 ggccggacag gccgcggtgg tcggggggga gcattccctc gggtgcgggc aggacgcgtt
     5881 cggaccagac cgtgagtccg tcggggtcga ggtcgcccgc ctcgatctcg gcggcgagtt
     5941 cgatccactg ccgcatcagg gtgaggacgg tggtgccgtc cgcgatgcag tgcggcaggg
     6001 tgagcaggag gtcgtggacg tcctgctcgc cgggttcggc gccggacgtg ctgatcacga
     6061 cggcgcgtgc cagcgggccc ctgctccagt cgaccggggt gacgagttcg tgtccgttga
     6121 cctccttctc ccagcggtcg tcggcggtcg cctccccggg cgccccggcg gtcaccgaac
     6181 gcagcgggat cgggttcccg ggggccgccg tgaagcgggg tccgcggccc gcggcgtcgg
     6241 cccggatggc ggtgcggagc atcgggtggc gctgttgcag ggcgtccagt gcctgggcca
     6301 ggagctcctc cgacagtccg ccgtggatcc gggcgtgcga gatgacgttg agcggggaga
     6361 tctggtcgac gatccagtac cagcgctcca gtgggctcag cgggcgttct gcctcggtgt
     6421 gcgcggcggg ccgcttcacg gctgcacctc catcgtgtgg tcgtctgtgg cgcgggtgcc
     6481 ggggaagtcc aggtactccg cgttctgctt gtcgagcacc gaggagggcg ccaggcggaa
     6541 gaagagattc cggcccatca accgcagtgg gctctcggtc tgctccagcc cgctgagcgc
     6601 gtgcgccccc tcgacgatcc ggcgcgtgcg gggacggcgt tccgcctcgt aggcccgcag
     6661 ggcccgctgc ggactgccgg gctcccgggc gaggtggtgg gcgaggacga cggcgtcctc
     6721 cacggccatg cacgcgccct ggccgaggct ggtcatcatg gggtgggccg cgtcgcccag
     6781 cagcgtgacc ggtccccgcc cccagctctc caggaacggg cggtcgcgcg cggggaacgc
     6841 ggtgatctgc tcgaacgggg tcgcggcgac ggcggcttgc acctcgtcgg cccagccggc
     6901 gtaggcgcgg acgatctcgt ccttgtcgcc gtcccagtcg cgggcgcgct ccgcgggcat
     6961 gttcttcgtg ccccaccagt agacccggcc gccgccgatg ttggcgagtc cgaagcgccg
     7021 tccgcggccc cagtagtggg cgccgtactg cttggtgacg cgcggatggg tgaactcggg
     7081 ggtggcgacc cagcagaggt agccggtctc gcgcggtgtc tcgggtccgg cgatctgccg
     7141 ccggaccgcc gagccgaagc cgtcggcgcc gatgagcacg tcgccgcggg cctcgcggcc
     7201 gtcctcgaag tggacgcgca cgccgtcgcc gtcgggggtg aagccggtgg ccgccgcgcc
     7261 gagtacgacc gggcagtcgc cgacctgctc cagcagcagc cgctggagca gggtgcgggt
     7321 gacaccgaag ctgggggcgc ccagccggtc gcagatctcc ttgaaccgca gcgtgcggat
     7381 gaccttgccg cgggcggtga ggaagtggag ctcctccagg atctcggcgt tctcctccag
     7441 ccggaggtcg atgcccaggg tgcgcagcgc caccaccgcg ttggtcatga aggacagcgc
     7501 cccgccggcg ggccgcagtt cccgcgcccg ttcgtacacc tcgacgtcca tgccgacccg
     7561 ccgcagacag gccgccgcgg cgagtccgcc gatgccggcc ccgacgacga tcgccttccc
     7621 gttccggcct gtcgtcactg tgctgcccct tcgtcggtga gtaccggttc ccggcccgtc
     7681 cggccgtccg gctcctccgt ccccgcggcc atcgccccgg cgacggcccg gccgacggac
     7741 cgcacgtgcg gctcgtccag gaggaggagg tggtcgccgg agacgtcgac gacgtccagc
     7801 cggccgctgg tgagggtcgc ccagccgttg gccggggcgt cgtgcagggt gcgggccgct
     7861 ccgtgcatgg gcctgaggac gtcgggcagc ggcgcggtcg ccttgatcag ggtgacgtcg
     7921 acggggtcgg gggccggctg gtagtcgcgc agcgaggccc agttggcctt gtagacctcg
     7981 aagagccggc ggacggccga gcgggcgccg cgggcggaca cgatcccggc ccgggccgcg
     8041 cgctcggcga tgaagtcgag ccgctcgtcg tcggtcccga gctcgtcggg gatgcgttcg
     8101 acgggggcgc tgcctccgcg gtcgacccag atcagctccc agaagaacca ctccatcatg
     8161 gcgcgctcgg ccacgtccgg gcgttccccg ggcgaggggg cgatggagtc cagcaggatc
     8221 agggaggcca cctcgtcccg tccggaacgc ttcagctgcc gggccatctc gaaggcgacg
     8281 aagcccccga aggaccagcc gcccaggtgg taggggcctt cgggctgcac tctgcggatg
     8341 gcctccagat agctcccggc gagcccctcc atggtggcga ccggctcggt gcccggttcc
     8401 gcgccggccg cctggagcgc gtacagcggc tggtcgtcgg gcaggtgccg ggccaggcgc
     8461 acgtagcaca ggacgttgcc gcccaggggg tggacgagga acaggggcgg ccggctcccc
     8521 ccgctcctga tgggcaccac ggggtcgaag gcggcggccg cgtccccggt gcgcagcagt
     8581 tcggcgagcc gggcgacggt gggggcggcg acgaaggccg tcagcgggac gcgtacgccg
     8641 aaccgcttct cgatggtgac gatcagccgc atcgccgtca gcgacgtgcc gccgctctcg
     8701 aagaagtcgt cgtggatccc gaatccgggg cgccccagca tctcgccgaa gatgtcggtc
     8761 agcgcccgct cgtgggcgtt gcgcggcggg gccgagccgg cttcccgccg ggtctccagc
     8821 ggtatccgcc gcagcgccgc gtcgtcgcgc ttgccgctgg gggtcagcgg caggcgcggc
     8881 agccaggcca ggtgcgcggg gaccatgtac tcggggagca cggcgcggag ccgtttgcgg
     8941 acctcctcca ggtcggcgga gccctcctcg ccgaggagga aggcgacgag gaaggagtcg
     9001 aggccgtcgc cgcggccgcg ggccaccacg gcggcgccgc ggatgccggg gaagtcgtcg
     9061 gacatcgcgg tgagggcgat ctcgatctcg gccggctcga cgcggaatcc gcgcaccttg
     9121 acctggttgt cggcgcggcc cagccagacg gtgtccccgc cgggcaggac ccggccgagg
     9181 tcgccggtgc ggtagagccg cacgcccggc ttcccgcagg ggtgcgggac gaagcgctcc
     9241 tcggtcaggt cggggcggcc ccggtagccg agcgccaggc aggcgccgcc gaggtagatc
     9301 tcgccccgga cgccggcggg caccggccgc agccgggagt cgagcacatg gatctcggcg
     9361 ccgtcgatgg cggtgccgat cgggggcagg gcgggccagc cggcggggtc gcccgagagc
     9421 aggtgggcgc tggcgatgtt ggtctcggtc ggcccgtact ggttctccag cagggtgccg
     9481 gggcgggccg cgcagaagcg gcgtacctcc tcggtgacgc gcaactgctc tccggaggag
     9541 atcagaacgc gcagggcgcg cggccggacg cccagcagct gtgacgcctc ggcgatctgc
     9601 tggagggcga cgaacggcat gaaccagcgt tcgatctcct gctcgtccat cagccgcagc
     9661 agcgcggagg ggtcgcggcg gtccggctcg gacaccaggt ggagggtgcc gcccgcggcc
     9721 agggtggaga agatctcctg gaaggagacg tcgaagctga gcggggcgaa ctgaagggtg
     9781 cgggcgccgg gcgcggcggt ctccgcgcgc agctgccact gcgtgtagtt ggcccacagc
     9841 cggtgcggga gttcgacgcc cttgggttcg ccggaggagc cggaggtgaa caggatcagt
     9901 gccaggctgt ccagggggag ggcgccggtc tcccgctctc cggtctccgg agtcccggtc
     9961 tcccgctccc cggccggctc ggctccgccg tccgggccgg gcatggggat cgactcgacc
    10021 ggcaggacga gcccggggtc ggggacgagt ccggcgtgcc gctcgtgggc gacgacccgg
    10081 aacggccggg cccgctccac catgcgggcg atgcgctccg gcgggtagct gacgtccagc
    10141 ggtacgcacg ccgccttggc ccgcaggacg ccgatcacgg tcgcgatcat ctcgggggag
    10201 cggtccagcg cgatcccgac cccggccccg ggctccacgc ccagctcgtg caggcgccgg
    10261 gtgacctgcc gcgccgcccg ctccagctcc gcgtacgtcc accgggtgcc gccgtgcacg
    10321 acggcctcgg cgtccggctg ccgggcggcc gtggcggcga acaggctcat gacgtcggcg
    10381 ggttccgcgg ccgggttcgt gggcagttcg tccgactcca ccaggaagtg gaagtccggt
    10441 gcctcctcgg ggtgttcgac gatgcggcgg aggatcgcgg tgtaggtgtc ggccagcagg
    10501 tccgcctgtg tggcggtgaa cgaccggccc gcgcagttca ggcgcagccg ggtgcgcccg
    10561 tcgcgggggt cgacgatcgc gttcaccagc agcgcgaagt tggtctcctc gtaggtcgtc
    10621 aggtccagca gctccaggtc cgcccgggcg aacagctcct ccagggtgtg cagccgcacg
    10681 aaggtgaagg ccgagtccag aagcggggcg ccgccgcggt cgtcctgcac ggcgctgagg
    10741 gggtaggcgc ggtgggggtg ggagtcgcgc tcctggcgga cgacgtcgcg gacggtctcc
    10801 agccagctct cctgccccgg gcgcaggcgg aacggcatcg tgttgaggaa caggcccgcg
    10861 atccggtcgg ccccctccgt ctccggacgg ccgtgcgtca ccaggcccgt cgtgacgtcg
    10921 tcggtgtccg ccaggagccg cagggtcagg cagtgcgcgg tgaacaggac cagccgcagc
    10981 ggcagggcgt ggccgcgcgc gaagcccttg agcgcctcgt cgaggtcggc ggggagttcc
    11041 acgtggcgca ccacgctctc ctcgcccggc gagggctcgt acggcacgaa cgggtcgagc
    11101 tgtacgggct cggcgccgtc gagcaggtcg cgccagtact cccgggactc gcgggactcc
    11161 agcagccgcc gctcgtcgcg cacgtggagg gccggggagg gcagggcggc gtcgggcacc
    11221 ggtgccacgt ccgcgccgag gccgtgcagg tagtcccgca gcagctcgga catcaggccg
    11281 gcgacgctcc agccgtcgag gatcgcgtgg tggaagctga ggacgaggtc gaggcggcct
    11341 ccgtcgcgga cgtgcgcgtg caggtggtac agaccgggac gctcgtggtc gtacgcatgg
    11401 tggcgccgct cctcgatgtg ttcgcgcagt gccttctcgg ctgccgtccc gtcggtgccg
    11461 cgcaggtcgg cgaccgacag cacgcccgtc acgcggggat ggacgatctg cagcggctcg
    11521 gagtggccgg ccagggcgaa ggaggagcgc agggcggggt ggcgggcgac gagccggtcc
    11581 gcggcggcgc ggaaggccgg ttcgtcccag gcgcaggcga ggcggtagtg gaagacgtcg
    11641 cggtagacgg tggaggtctt ctcctcgctg ctgtggtaga gcatgcccag gtggaggcgt
    11701 gtggccgggt aggcgtcctc ggccccggtg ccgagcagcc gggcccggtc caccccgggc
    11761 accagggcga acggctcggg ggcggcctcg ccgtcgtccg cggtcgcggg ggtgacgcgg
    11821 gcggccagtt cggcgacggt ggtgtgccgg gccaggtccg ggagggtgac ccgcaggccg
    11881 cgcttctccg cctccgcgcg gacccgcagc atcaggatcg agtcgccgcc gagcgcgaag
    11941 tagtcgtcgt ggggaccgac ttgttcgact ccgagcacct tcgaccagat ctccgcgagc
    12001 gccgcctccg tggcgttgcg cggagcctgc ccggaacccg ccccgcggcc cgcctccgcg
    12061 gggagcagcc gccgcagggc gccgcggtcg gccttgccgt tgggggtcag cgggatccgg
    12121 tcgacgcgga cgtaccgcgc cgggatcatg tagtcgggca gcgactgggc gagcgcggcg
    12181 cggaggccgg ccgcgtccag gtcgcggtcg gcgacgtagc agccggccag ccgcacggag
    12241 cggtcctcgt cgaccgtgtc gaccaccacc gcgccgcgga cgccgggcac ccgggagagc
    12301 cggtgctcga cctcgccgag ctccacccgg ttgccgcgga ccttcacctg gccgtccatc
    12361 cggcccaggt actccagttc gccgtccgcg agcctgcgtg ccaggtcacc ggtgcggtac
    12421 aggcgcccgc cgggggtgaa ggggtcgtcg gtgaacttcc gcgcggtcag ctccgggcgg
    12481 ccgaggtagc cgcgcgcgac gccgtcgccg gcgacgcaga gctcgccggg ggcgccggcg
    12541 ggctgggggt tgccgtgccg gtccaggacg tggaggcgga tgttgtcgat gggccggccg
    12601 atgggcaccc ggccgacggg ccgggagggg tcgccggggc agtcgtggaa ggagacgtcg
    12661 acggtcgcct cggtcgggcc gtacaggttg accagccggg tgccggccgg gccgaggagc
    12721 cggttgaagc ggttgacctg ttccgggggc agcgcctcgc cgctgcagaa gacgcggcgc
    12781 agcgagcccg cctcagcgcg cagctcgggc cggctctcca gcaggtcgag gaagggcccg
    12841 aacatcgacg ggacgaagtg gacgacggtg acgccccgct cgccgatggt gcgcagcgtc
    12901 tcgcgcgggt ccttctcggc gccgggcgcg agcagggcga gccgcgcgcc ggcgagcccc
    12961 caccagaaca gctcccacac cgacacgtcg aaggagatcg gggtcttctg cagcagcacg
    13021 tcgccgtcgc cgaccgcgta gcggcgctgc atccaggtga gccggttgac gaccgagcgg
    13081 tgctcgacca tgacgccctt gggccggccg gtggagcccg aggtgtagag cacgtacgcc
    13141 aggtcgtgcg gtccgccgga gtccggcagc ggcccgaagg gcccggtgag gggttcgtcc
    13201 gcgcggcgga cgacggccgg gccccggggc ggcgcggggg tgccggggcc ggtcaggatc
    13261 gcccgggcgc cgctgtcctc cagcagcagg cggatgcgct cggcggggtg tgcgggatcc
    13321 accggcacgt acgcggcgcc ggccttcagc acggcgagga cggcgaccag cgtggacgtg
    13381 gagcgctcca gcgcgacggc cacccggtcg ccgggctcca cgccgtccgc gcgcagggcg
    13441 cgtgccaggc ggcccgcccg cgcgtccagt tcggcgtagg tgagggcgtc gccgcttccc
    13501 gggccgacga ccgcggtgcg gtcgggggtc cgcgcggcct gctcctcgaa gaggccgtgc
    13561 agggtccggt ccgccgggta gtccaccgcg gtccggttga ggccgtggac gatctcctcg
    13621 cgctcgtccg ggtcgagcat cccgatcgcg ccgacggggc ggtcggggtc gcgcagggcg
    13681 tccaggacca ggttgcggat gtggcggccc agggccgcgg cggggaagtc ctcgtcgaag
    13741 acgtcacggg cgtagtcgag ttcgacggtg atgtcgccgg tgccggccgt ctcggcgacc
    13801 acgaccgcga gggcgtcccc gtcgtgtgcg cgggtcccgc cggcgaactc ctgccgcagg
    13861 cccgggatct cccgggggct cggccactgg acgtaggaga ccgtgacgtc gaacagctcg
    13921 cgggggctgc cgggcgggag gtcccgcagg acgtccccca gcggcagccg ctcgtggcgc
    13981 tggagttcgc gggagccggc ctggacggcg gcgacgagtt ccgcgaaggt cgcggccttc
    14041 gccacgggca cccgcagcgg gagggtgttg gcgaagtggc cgaccgtgcg ccgctgcgtc
    14101 ctgccccgcc ggttgaacag cgggacgccg atgaccacgt cgtcggcgag gtggacgcgg
    14161 gagaggtagg cggcgaaggc cgccgtgacg aaggcgaacg gcgactggcc gcgttcgcgg
    14221 atccgctcgg cggcctcgcg cggcagcccg aaggagtggc gcccgctgcc gcgcgatccg
    14281 ctgggcgccc gcctggtgaa cagcggcggg acggcgcccg ccagggcggt gcggaagtgg
    14341 tcgcggtccc tgccgtactg cggggagttc cggtagcgct cctcgtcctc cagggcggcg
    14401 aggcaggacg gggccggcgc gtcgtcggcc tcccccgcgt agtgggcgcg gacctgctcc
    14461 aggaggaggt tcagtcccca ggcgtcggtg aggatgtggt gggccttcac gtaggcgtgg
    14521 gccgcggtgc cgctctcctt gagcaccgcc agctcgtacg ccgggccacc ggtgagggac
    14581 agggggcgtc cgaaggactc ggccatccac gcctcgcagg ccgcccgggg gtcgggctcg
    14641 ccggtgaagt ccagcatccg cacctgcggc ccgtcggagg agtccacgcg ctggaggggg
    14701 gtcccgtcct cctccgtgaa ccgcaggcgg agggcgtcgt tgcggcggac cgcttccagc
    14761 aggcaggccg cgagccggtc ggtgtcgacc gggcccgtca gccgctggga gacgaagaga
    14821 ttgaactggg ggagcttcgg gaacagggcg ttggccaccc agatatcacg ttggtatgcc
    14881 gtcagcggtg cccactcgaa tgaattcaag atgtcctcta ctcgggtcgc ctcggagtcc
    14941 aatctcgcag ccgaaccctg acccgggaat ttcggatcat ccagaaagcc ccgggactgg
    15001 tactgggagt accagcaccg cggtacccgc atgaacggct ctcccctgcc gactcctcgg
    15061 accaagtacg gaaagcggga aaattcaccg gcccctctgg cgaaatcccg tcccggatga
    15121 caagaatcct tggacgaacg cctcggccgt cgtcgggtca cccctgggag gaagttccgt
    15181 gagcgcacaa gtaccgctgg tcgccgccca ccccgtgctc gggtcgctgc gggatctccg
    15241 ccacgacacc ctgggcgcct acctcagggc ccggcgcgac cacggtgacg tggtcaggtt
    15301 cgacgccggc ccgccggggc tgcgcgccag cctctacgcg gtcttctccc ccgagggcgt
    15361 gcagcaggtg ctcggttccc aggcgtcgaa cttccgcaag gagaacgacg tctacaccga
    15421 gatccgggag tccatcggaa acggcctgct gaccagccag gacgaggatt acatccgaca
    15481 gcgccgcatg atccagccgc ttttcacccg ccgccgggtg gacgcatatg ccagtgccgt
    15541 gtacggtgag gccgtcgcca ccgccgaccg ctggaactcg ctttccgaaa aagtcgtcga
    15601 cgcggccgag gaaatggccg agttcgcact cagaacggtt acccgtgttc tgttcggagc
    15661 tgatatcgat gccgccgcgg acgtcgtccg gagaaatttc ccggtcatcg gcgagagcgt
    15721 tctgcggcgc ggtgtgacac cgttgcgcct gccccgccac tggccgactc cggccaaccg
    15781 ccggacgcag gcggcccagc gggagctgta cgccatctgc gaccgcatca tcgccgagcg
    15841 ctccgccact ccgggtgagg ccgacgacat gatctcccgg ctgatcctgg cccgcgacga
    15901 ggacgggtcg gccctctccc ccgacgcgat ccgcgaccag gtgctggtct tcctcctcgc
    15961 cgggcacgag acgacggcga ccgcgctcgc cttcgccctg cacctgctcg cctgccaccc
    16021 cgaggcccag gagaaggcgc acgccgaggt cgacgcggtg ctgtccggtg gtacggccgg
    16081 cgccgagcac ctggacgaac tgccctatct gacgcgggtc ttcaaggagg ctctgcggat
    16141 gtacccctcg gtcgcgatca tgggccgccg cagcgtggcc gacagcgagg tctgcggctt
    16201 ccacatcccc ggcggctccg acgtctacgt gagcccgtgg gtcacccagc gccaccccgg
    16261 ccactgggag caccccgacc ggttcgaccc cgaccggttc gccccggagc tggaggccgc
    16321 gcgcccccgg tacgcctggt tccccttcgg cggcggccct cgtgcctgca tcggccagta
    16381 cttcgccatg ctggagggcg tcatcggcct ggccggcctg ctccagcgct tccgcctcac
    16441 cgctccgaag accgagatcg ccctccagct cggcatgacc ctgcgtgccg cggaaccggc
    16501 gcacgtgcgc ctgacgcccc gcgacggcgc ccgcggccgg gtgccgagga gggcgggaac
    16561 ggagtgaggg agatcctgga cgcgatcctc gcgtcggaca gcaagcccgc cgacttcgcc
    16621 aacctggcgc tgcccgagtc ctaccgcgcg gtcaccgtgc acaaggacga ggccgacatg
    16681 ttcgccggaa tgcccacccg ccagaaggac ccgcgcaagt ccctgcacct ggaccaggtg
    16741 cccctgccgg aactgggccc gggcgaggcc ctggtggcgg tcatggcctc ctcggtgaac
    16801 tacaactcgg tgtggacctc gatcttcgaa ccggtcccca ccttcggctt cctggagcgc
    16861 tacggccgca cctcacccct ggccaggcgc cacgacctgc cctaccacat catcggctcc
    16921 gacctggccg gcgtggtcct gcgcaccggc cccggcgtca acgcctggca gcccg
//
