LOCUS       NZ_FOSG01000034        20562 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces pini strain PL19, whole genome shotgun sequence.
ACCESSION   NZ_FOSG01000034
VERSION     NZ_FOSG01000034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces pini
  ORGANISM  Streptomyces pini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900114215.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:14:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,762
            CDSs (total)                      :: 5,677
            Genes (coding)                    :: 5,560
            CDSs (with protein)               :: 5,560
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 3, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 20 of 117
            Pseudo Genes (incomplete)         :: 111 of 117
            Pseudo Genes (internal stop)      :: 1 of 117
            Pseudo Genes (multiple problems)  :: 15 of 117
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 13984
            Orig. end                         :: 34546
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOSG01000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20562
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="butyrolactone"
                     /product="terpene"
                     /region_number="1"
                     /rules="AfsA"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20562
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="AfsA"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="butyrolactone"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10924
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10924
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:5924](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5924
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    complement(1393..1406)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.9"
                     /tool="antismash"
     misc_feature    complement(1394..1403)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.58"
                     /tool="antismash"
     misc_feature    1396..1409
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.63"
                     /tool="antismash"
     misc_feature    1399..1412
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.1"
                     /tool="antismash"
     misc_feature    1402..1415
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.82"
                     /tool="antismash"
     misc_feature    1665..1679
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.87"
                     /tool="antismash"
     gene            1997..2569
                     /locus_tag="BM237_RS27805"
                     /old_locus_tag="SAMN05192584_13414"
     CDS             1997..2569
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="BM237_RS27805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13414"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_175541162.1"
                     /transl_table=11
                     /translation="MRTRERVLQAAAGEIVRSGYHGTALVRVAARAHVTLGAVSFHFPT
                     KQALVQEVYLDGVKRTSEAVEAEVGEDTEPLQGLANLTLRLASLLIDDDLTVLACSRLS
                     RDDPTGHFAWRDTWRGHVARLADRACSSPGSTVNCSRKTLGFLVHCLLAGTEVWAVHAD
                     AERHAALSHLAAAWQQAMPGGRMDTEG"
     gene            complement(2589..3323)
                     /locus_tag="BM237_RS27810"
                     /old_locus_tag="SAMN05192584_13415"
     CDS             complement(2589..3323)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (0-161). E-value: 1.1e-08. Score:
                     27.2. Matches aSDomain:
                     nrpspksdomains_BM237_RS27810_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452957.1"
                     /locus_tag="BM237_RS27810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13415"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_093852527.1"
                     /sec_met_domain="adh_short (E-value: 9e-34, bitscore:
                     108.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITGASSGIGAESARLFAAEGAAVVLTARRAGHLERLGAEIRAAG
                     GRALAAPGDVTRPQDMRDVVEKAVDTFGRLDAAFNNAGWTSTGTAFHEIGDDEYDRIIG
                     VNQRGVWNAMRAQITAMLAAGTGGAIVNTSSVAGVRATGVAAPYIAAKHAVIGLTRAAA
                     DEYGAYGIRVNALVVGSTGTELMQEVLARTPDLFGPFVERAIQQRLAAPREVAQAAVWL
                     CSDRSSFITAAAVPVDGGWTAR"
     aSDomain        complement(2841..3323)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS27810_PKS_KR.1"
                     /evalue="1.10E-08"
                     /label="BM237_RS27810_PKS_KR.1"
                     /locus_tag="BM237_RS27810"
                     /protein_end="161"
                     /protein_start="0"
                     /score="27.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="MITGASSGIGAESARLFAAEGAAVVLTARRAGHLERLGAEIRAAG
                     GRALAAPGDVTRPQDMRDVVEKAVDTFGRLDAAFNNAGWTSTGTAFHEIGDDEYDRIIG
                     VNQRGVWNAMRAQITAMLAAGTGGAIVNTSSVAGVRATGVAAPYIAAKHAVIGLTRA"
     CDS_motif       complement(3234..3320)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS27810_0001"
                     /evalue="6.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BM237_RS27810"
                     /protein_end="30"
                     /protein_start="1"
                     /score="15.5"
                     /tool="antismash"
                     /translation="ITGASSGIGAESARLFAAEGAAVVLTARR"
     gene            complement(3375..4280)
                     /locus_tag="BM237_RS27815"
                     /old_locus_tag="SAMN05192584_13416"
     CDS             complement(3375..4280)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268973.1"
                     /locus_tag="BM237_RS27815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13416"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_093852513.1"
                     /transl_table=11
                     /translation="MAAGSHSTAESCPGRADRRIVVTGATGTVGRHVAGLLASEVSCHG
                     VFLTRDPAGAALAGRVIRADFEDIARLTEVFAGADAVLIITNDPLRPDHDANIVTAAVA
                     AGVGHLVKLSALAVADLRAQDFITSWQRAAEDRIRQCGIPWTILRPRAFMTHALAWAPD
                     IRRDATVRALHPTSRNACIAPSDIAQVALRVLLEGGHHGRTYALTGPRAISVRDQAAQL
                     GEVLGRRLTCAGLTIAQAQERWRRRYPEVMVRALTASAERQRAGAKEETTPDVGDLLGR
                     PATSFSSWAEEHAHLFGPRV"
     misc_feature    complement(4032..4034)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4173..4175)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4281..4904)
                     /locus_tag="BM237_RS27820"
                     /old_locus_tag="SAMN05192584_13417"
     CDS             complement(4281..4904)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891475.1"
                     /locus_tag="BM237_RS27820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13417"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_245794093.1"
                     /transl_table=11
                     /translation="MSDLKQGRAAHTRQRLLMAAAELFDEHGYRGTNVADIARRAGLTL
                     GALYFHYGNKRGVAEAVMNSQPQAIEPLLQSEGVQHVIDITMVWARRLQLDPLLRAGVR
                     LAVEQRSHDMSDPTSFNNWASIMAGYLQEARDNGELRPEVDPAALARFVVGACTGVQLY
                     SQLVSCRADLMDRTCEMWQILLPGITSEEAHARLVVDPARGCTE"
     misc_feature    complement(4925..4934)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     misc_feature    complement(4927..4940)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.1"
                     /tool="antismash"
     misc_feature    complement(4928..4943)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    4935..4948
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.19"
                     /tool="antismash"
     misc_feature    4935..4949
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.13"
                     /tool="antismash"
     misc_feature    complement(4937..4950)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.85"
                     /tool="antismash"
     misc_feature    complement(4939..4955)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.88"
                     /tool="antismash"
     gene            5001..5924
                     /locus_tag="BM237_RS27825"
                     /old_locus_tag="SAMN05192584_13418"
     CDS             5001..5924
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="BM237_RS27825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13418"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_093852514.1"
                     /sec_met_domain="AfsA (E-value: 1.6e-22, bitscore: 70.6,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATFADRPGTAVPQHMVHKHTHTEVLLTGWSAHADDAFTVTARW
                     PRAHSFYRPRGHYESLLFAETVRQTLPLLSHEAFGVPFGHQFVWSDLSFGVAYDALWAS
                     DRTMDLTLTVECSEVTRRRAGFSSARVSVCASTNTTTVGHARTRFSVHSPDVYRRLRAG
                     RHDTAAARASALRPTPGVLPASVGRHLPQDVVLAPTVHSDVWRLRVDLSHPILFDHPVD
                     HAPGMLLLEATRQAVLSVHPTGDAVVTSMAARFHRYVELDRPAWVRLASGTHGSFSVSI
                     DQDEQTCFEAEATTKTVSHGSVKRSV"
     misc_feature    5079..5081
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5181..5183
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<6030..6455)
                     /locus_tag="BM237_RS27830"
                     /old_locus_tag="SAMN05192584_13419"
                     /pseudo=""
     CDS             complement(<6030..6455)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477235.1"
                     /locus_tag="BM237_RS27830"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13419"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSENVTEAETVESGEPQAKAAEDRLIDELVGRAQAEGLQLTGEG
                     GLLQQLTKRLLESALEGEITDHLGYDKHDPAGKNGGNSRNGTRSKTVLTDVGPVEIAVP
                     RDREGSFEPKIVKKRQKRLTGVDEMVISLSAKGLTTGK"
     cand_cluster    6040..20562
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    6040..20562
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[16039:16459](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      16040..16459
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            6624..>6821
                     /locus_tag="BM237_RS27835"
                     /pseudo=""
     CDS             6624..>6821
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025180.4"
                     /locus_tag="BM237_RS27835"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ISAs1 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPAAVSSPIPPVLVKLGPLDVSQVADLRPFLDLVPDPRARRGRWY
                     RLTAVLLVCACAAVSGARSVD"
     gene            complement(7185..8195)
                     /locus_tag="BM237_RS27840"
                     /old_locus_tag="SAMN05192584_13420"
     CDS             complement(7185..8195)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643283.1"
                     /locus_tag="BM237_RS27840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13420"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_093852515.1"
                     /transl_table=11
                     /translation="MPRPFTLFTGQWADLPLEEVCGLARDFGYDGLELACWGDHFEVDR
                     ALEDQDYVRGRRELLARYGLRCWAISNHLVGQAVCDRLIDERHQAILPGRIWGDGDPEG
                     VRRRAAAEMADTARAAAALGVDTVIGFTGSSIWHLVAMFPPVPPEMVERGYADFAERWG
                     PILDVFDTEGVRFAHEVHPGEIAYDYWTTHRALEAVDHRPAFGLNFDPSHFVWQDLDPV
                     GFLYDFRDRIYHVDCKEARKRLDGRNGRLGSHLPWGDPRRGWDFVSAGHGDVPWEDVFR
                     MLSSIGYDGPVSVEWEDPGMSRLQGAPEALRALKRFDFEPPTASFDAAFGGDRRS"
     gene            complement(8216..9415)
                     /locus_tag="BM237_RS27845"
                     /old_locus_tag="SAMN05192584_13421"
     CDS             complement(8216..9415)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848457.1"
                     /locus_tag="BM237_RS27845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13421"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_093852516.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 9.9e-28, bitscore:
                     88.4, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 7.2e-32,
                     bitscore: 101.2, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHSDRREYGEPTPDLGIGMVGYAFMGVAHSQAWRTVRHAFPLPL
                     RPRLAMISGRDEAAVGAAARQQGWAAAVTDWRAVVDSDDVDLVDICTPGDSHAEIAIAA
                     LEAGKHVLCEKPLANSVPEAEAMVEAARAASRRGQVAMVGFNYRRVPAIVQARRLIAGG
                     RLGALRHIRVTYLQDWLVDPEFPLTWRLSREKAGSGALGDLGAHAVDLAQYLSAEPLAG
                     VSALTETFVSERPLVAAMLTGNDGPRARGPVTVDDAALFTGRLASGALASFEVSRVAAG
                     RKNALCVEINGELGSLAFDLERLNELSFHDHTEPATTAGFRRVLVTEPEHPYLEAWWPP
                     GHALGYEHTFTHQAHDLVQAIATGTDPAPSFTEGLQVQRVLAAVEESAAKNASYTPVPV
                     "
     gene            complement(9452..10492)
                     /locus_tag="BM237_RS27850"
                     /old_locus_tag="SAMN05192584_13422"
     CDS             complement(9452..10492)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138429.1"
                     /locus_tag="BM237_RS27850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13422"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_093852517.1"
                     /transl_table=11
                     /translation="MPEKNLTSRRRVLFGAAIGAGALVTGCTSNASSSDESAAAAPETA
                     DKPGKPVTIGFAGPQADHGWLNAINENATRRAEQYEDVTLEITEGSNDTATQIGQITTL
                     INKKVDVLVILPADGKALTQTGLEAMRAGIPVVNLDRIFDSPQAYRCWIGGDNYGMGLN
                     AGRYIGERLKDVADAKVVELAGLDTLELTKQRTRGFDDALSNYPNITKVARQAAEFTVE
                     SGQAKMAQLLQAQKDFDALWNHDDDQGVGALRAIEQAGRDEFVMVGGAGSKSAMEAIQS
                     DDSVLKATVLYPPTMAASAIDLARALGQGKGVSGLAELEIPSSLTLYSAIVTKDNVEDY
                     LPTGFI"
     misc_feature    10473..10488
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     misc_feature    10480..10494
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.16"
                     /tool="antismash"
     gene            complement(10555..11514)
                     /locus_tag="BM237_RS27855"
                     /old_locus_tag="SAMN05192584_13423"
     CDS             complement(10555..11514)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309348.1"
                     /locus_tag="BM237_RS27855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13423"
                     /product="ABC transporter permease"
                     /protein_id="WP_245794094.1"
                     /transl_table=11
                     /translation="MARLGRQADVRNLSLLGVLAILVAVGGVTEPDTFLAGSNLQLVLT
                     QASIIGVVTVGMTFVITGGGIDLSVGAIVALASVWATTVATQEYGFTGILFTAVVVGVG
                     CGLVNGILVAYGGMVPFIATLAMLASARGLALQITDGRTQIVTVDAVLDLGTPDAYVLG
                     IPPLVLVFGAVTALGWLLLNRTTFGRRTLAVGGNAEAARLAGIDIRRQRLYLYVLSGLC
                     CGIAAFLLIILSGSGQNTNGNLYELDAIAAVIIGGTLLTGGRGTIVGSVLGVLIFTTIT
                     NIFALNNLQSDVQQIAKGAIIVAAVLVQHRTLRRTGGA"
     gene            complement(11619..13133)
                     /locus_tag="BM237_RS27860"
                     /old_locus_tag="SAMN05192584_13424"
     CDS             complement(11619..13133)
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374111.1"
                     /locus_tag="BM237_RS27860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13424"
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_175541163.1"
                     /transl_table=11
                     /translation="MSDIIKVFPGVRALDGVTLQVEAGEVHCLLGQNGAGKSTLIKVLA
                     GAHRPDSGTVTWRGEEVVLRSPIAAMRLGIATIYQELDLVEGLSVAENVFLGHERTAAG
                     FVIRGRDTRVAAAELLRRLGHEEIDASRAVGELSAAQRQIVSMARALSHDVRLIVMDEP
                     SAALDPDETENLFRIVRELTADGVAVVYISHRLEEIRRIGDRVTVLKNGRSVAGGFAVE
                     ETSDREIIALMTGREIEHVFPGRPAPRESAPAVLRTRGLAREGEFAPLDLELRAGEIVG
                     LAGLVGSGRSEILETIYGARRPSAGEVSVDGRRLRPGSVRSAVAAGLGLAPEERKAQGL
                     FQLESVTRNVSVSTLSRFARLGWLDRRGERVATKAVTRELSLRPDDPDVLIRTLSGGNQ
                     QKAVLARWLLRDCRVLLLDEPTRGVDVGARAELYGVIRRLADAGLAVLLVSSELPEVLG
                     LADRVLVLREGRVVDAAPALDLDEDRILDLLMAGHADTTSPGTEPS"
     gene            complement(13298..14479)
                     /locus_tag="BM237_RS27865"
                     /old_locus_tag="SAMN05192584_13425"
     CDS             complement(13298..14479)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378316.1"
                     /locus_tag="BM237_RS27865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13425"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_093852519.1"
                     /transl_table=11
                     /translation="MTARPANTHQAHLLRLLRDGGRSSRAELGERIQLSRSKLAVEIDR
                     LLETGLVATDGFAASRGGRRSHSVRLAPGLRFLGVDIGATSIDVAVTNGELEVLGHLND
                     STDVKDGPVAVFEQVLAMAEKLKESGLAEGFDGVGIGVPGPVRFPEGVPVAPPIMPGWD
                     GFPVREALSQEFGCSVMVDNDVNLMGLGEQHAGVARSVADFLCVKIGTGIGCGIIVGGQ
                     VYRGVTGCAGDIGHIQVDPQGRLCACGNRGCLEAHFSGAALARDAEEAAHSGRSAHLAV
                     RLEASGRLTSADLAAAAAAGDPVALDMARTGGERVGQVIAGLVSFFNPGMVVIGGGVTG
                     LGHTLLASVRSQVYRRSLPLATGNLPIVLGELGGMAGVIGATRLISDHLFSPA"
     gene            15188..15415
                     /locus_tag="BM237_RS27870"
                     /old_locus_tag="SAMN05192584_13426"
     CDS             15188..15415
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013698.4"
                     /locus_tag="BM237_RS27870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13426"
                     /product="transposase"
                     /protein_id="WP_342746267.1"
                     /transl_table=11
                     /translation="MYDEPAEVSVPEIRAGMDIGKTHHHTVVINADGGRSLSRRVQNDE
                     SELLELTGDILAISTDALWAVDLNQGALPC"
     gene            complement(<15464..>15598)
                     /locus_tag="BM237_RS27875"
                     /pseudo=""
     CDS             complement(<15464..15598)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="BM237_RS27875"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAGRGHRRRGDREMLAAIIFVATSGRTWNQLPPRFGLSRATASRR
                     "
     misc_feature    complement(15599..15613)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.0"
                     /tool="antismash"
     gene            16040..16459
                     /locus_tag="BM237_RS27880"
                     /old_locus_tag="SAMN05192584_13427"
     CDS             16040..16459
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.4"
                     /locus_tag="BM237_RS27880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13427"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_217655940.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.6e-15, bitscore:
                     47.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.4e-08,
                     bitscore: 24.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQRLSGLLWTATESLPAEVRPHVRALVAHWHTTDDIADEGRLAG
                     REARLAQWCADSLAEVRAGHSEHPLRRALVHTVRSRESDIALLEEFLDATRRDSAAPPA
                     FGTAADLRRYLRSVTGAPSGLTARCWRPAPGKGRS"
     gene            complement(16593..17015)
                     /locus_tag="BM237_RS27885"
                     /old_locus_tag="SAMN05192584_13428"
     CDS             complement(16593..17015)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129063.1"
                     /locus_tag="BM237_RS27885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13428"
                     /product="VOC family protein"
                     /protein_id="WP_093852530.1"
                     /transl_table=11
                     /translation="MSPDASPSSVWPVLHYDDTRAALRFLVDVLGFTEVIAAPDEYGGI
                     GHAELRWPGGGALVFGSTRHTDSVHGRMRAGTSAVYVVSDDVDAVHQRVVGAGGEVLEA
                     PHETRFGSGAVAYVCTVQDPEGNLWTFGTYRGPSPE"
     gene            complement(17378..17572)
                     /locus_tag="BM237_RS27890"
     CDS             complement(17378..17572)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM237_RS27890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_217655941.1"
                     /transl_table=11
                     /translation="MKIEIRPYANDDWATVARIHDAARLDELCDSAGVEAFLTPARTAQ
                     EEGLFDGRLWVGWRRPTGQ"
     gene            complement(17796..18386)
                     /locus_tag="BM237_RS27895"
                     /old_locus_tag="SAMN05192584_13429"
     CDS             complement(17796..18386)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470350.1"
                     /locus_tag="BM237_RS27895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13429"
                     /product="choice-of-anchor C family protein"
                     /protein_id="WP_093852521.1"
                     /transl_table=11
                     /translation="MLLTRSCTTAAVAAVLFAAAGTATAAPTASRFDDGSFEYPAVAAN
                     SFQSFAAGASMGPWKVTSGAADLIGAGFWQAAEGDQSLDLNATVPATVAQTFTTTPGKT
                     YTVTYSLAGNPDGASPLKTGRALVDGQNFQDFSFDTAGKTRSNMGYVTRQFTFVANNPT
                     TTLAFASTTPNSAHGPVIDDVRVHTCCSDSCCR"
     gene            complement(18805..19026)
                     /locus_tag="BM237_RS27900"
                     /old_locus_tag="SAMN05192584_13431"
     CDS             complement(18805..19026)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM237_RS27900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05192584_13431"
                     /product="hypothetical protein"
                     /protein_id="WP_139238196.1"
                     /transl_table=11
                     /translation="MPAPHGQDGAAAAPAPTSSSPRPGWYRLRAHARGRDAAFKDVRED
                     PAENHLLLCRPAEQTPIRMIHATDRCDR"
     gene            complement(19145..19468)
                     /locus_tag="BM237_RS27905"
                     /old_locus_tag="SAMN05192584_13432"
     CDS             complement(19145..19468)
                     /GO_process="GO:0006952 - defense response [Evidence IEA]"
                     /GO_process="GO:0045926 - negative regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020682.4"
                     /locus_tag="BM237_RS27905"
                     /note="Members of this family of antimicrobial peptides
                     occur in plants, but also in bacterial genera such as
                     Microbispora, Herbidospora, and Streptomyces.; Members of
                     this family of antimicrobial peptides occur in plants, but
                     also in bacterial genera such as Microbispora,
                     Herbidospora, and Streptomyces.; Members of this family of
                     antimicrobial peptides occur in plants, but also in
                     bacterial genera such as Microbispora, Herbidospora, and
                     Streptomyces.; Members of this family of antimicrobial
                     peptides occur in plants, but also in bacterial genera such
                     as Microbispora, Herbidospora, and Streptomyces.; Members
                     of this family of antimicrobial peptides occur in plants,
                     but also in bacterial genera such as Microbispora,
                     Herbidospora, and Streptomyces; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SAMN05192584_13432"
                     /product="MiAMP1 family antimicrobial peptide"
                     /protein_id="WP_093852523.1"
                     /transl_table=11
                     /translation="MRNQHTVRTTVTAAMTAAVLAVSTGAAFASSFRGWSGAHYTGTSS
                     EVTRCGCSNLSLGHRGSYRFDHTGQDASMFNTRNCQGSPHYTFRGDASSPAPVGWRSIY
                     IHC"
     misc_feature    19645..19660
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.53"
                     /tool="antismash"
     gene            19736..>20562
                     /locus_tag="BM237_RS27910"
                     /old_locus_tag="SAMN05192584_13433"
     CDS             19736..>20562
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578538.1"
                     /locus_tag="BM237_RS27910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_13433"
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="WP_175541164.1"
                     /transl_table=11
                     /translation="MDRPSAQTSRTRSLRIRAGVAFATCVALLVGGATTLDGRDAYAAE
                     PNLVQNGGFESGLSGWTCSAGSGTAVSSPVHGGTAALKATPAGSDNAKCTQTVAVQPDS
                     QYELSAWVQGSYVYLGASGTGTTDVSTWTPGGSGWQQLRTSFTTGPDTTSVTVHTHGWY
                     GQSAYHVDDVSLAGPGGDPGEPDPDPQPPAAPATPAVGATTSSSVTLNWNAVDGATGYT
                     VYQDGTKALSVQGTSATVTGLAAATSYEFRVSAVNGAGESAKSAPVTATTDRTG"
ORIGIN
        1 gagattcccc atgatgtgcc gacagccggt cggcaaacgc gttccaggcg tgtgcgcacc
       61 cccgggccgc ctccgatacc gcggttgcgg catgtggggg cacggtcgcg acgagctcct
      121 cccagcgctg ctccgggagc cggtgtgcta tcagcaggcg gagcaagcgg cggccgtctt
      181 ccgtgaggcg gagggacggg tccttcgtca ggctccacac cgtcaccgcg ggctgctcca
      241 ccgactttgc gggcagcgtc gtggagagct cgtccatccg gtcttcgctc tttggccgtt
      301 ggttctgcgg gacgacgtgc tccccgcgtc gcaggcgttc gcggacgtcg cgcacagtcg
      361 atggcgacac gccggccttc ctggccacgg tgcgcaatga cgcttgaggg ttcttctcca
      421 tcatctcgcg cgcccgcagt cgcccgtcgg cggtgctgac cggacgtgcg cggccatcac
      481 gaccgacccg ggacaccggg ctggccgacg cggtgtcccg ccggagcgag cgaaccgtct
      541 tggcggagac accggccact gccgcgaccg cccggtcgga ccactgcggg tgcgagccga
      601 gaagacgctt ggctgccgcg gacctctctt cggcggagag tggtagaccg tgcgtggtgt
      661 tcaccttgac ggcgaacgcg aaggcgtcct gctcgctccc ctcgaagtac cgcactgcca
      721 catggctctc gcctctgagc acagccgctt gacgccggtg cattccgtcg atgatccgca
      781 tcgtgccgcg gtggaccacg atcggtggaa gaaccgcgtc cgactcggcg aggagactca
      841 cgtgccgact gtcggtgccc tgcttgcggg gtgagtcggc cgggcggagc agagcgatcg
      901 ggactttctc cacttcggac agcgggggtc ccggtaactc cggagcctgc ccctcactgc
      961 tgcgcccggg cgcctggccc gctcggcacc cggcaggctt ctgcgggagc atggcctcag
     1021 cactcatcag taaccctccg aaagtagacc gcgtgcagca ggatgcgccg accggcgcct
     1081 ttcgtggcga tcgaggtgtc gcgccgggag ccgacttcgg cgaagcccca ttccgggcgg
     1141 ggcccgcgca acccgactcg ctcgtccggc gggcggcgca ctggcctcgg gcgggaaacg
     1201 cgggaggtcg gcgtcggcga ccggtgcatc gcgaacctcg gtcggcaccg atgaatcgga
     1261 cacgtagtac ctgcggcacc ggcggtcacc gggatgtacg gtcgagcacc tccacgccgc
     1321 cacacgctct tccaagcagt cggcgcgccc atgggtggtg ccccccgtca gcagccgtgc
     1381 gtgcccaacc cattacaaaa atattatttt tatggtgcgt cgccagcacc aagaagacaa
     1441 gggggcgaaa gtaccgaccc accccggggc aaggcgacac gccgacccgc acctcactcg
     1501 ccgacgcgac cggggtgccg gacgcaccga ctcgacccgc cgagaactcc cggcaggaaa
     1561 aggtcccatt tgacacagaa gtgccctttt cgcattcttt caccaccttg acccctcggg
     1621 tgcggacgtc cgcgatgacg gccggacaag cggcgccgaa cgaaatcttt cagccaataa
     1681 gccggactcg cgcccccttc ccggatcggc aacggcagaa tggtttcaag tagcaactct
     1741 tcgggaggcg tgatgactcc gtccgcaatc cgcgccgaca gcacatccct ggccgatgcg
     1801 acctgcccgg tggcgcgcaa tgcgtccggg aagagctcag gcctccgatg cccccgctta
     1861 cgcacgacag ccgaaggccg gccagcaccc ggccttctct gaaacggtca gcaagcccga
     1921 ttacccacga tccacaccgg ctcccgcacc gacccgcggt ggatcacaag aggttgaagt
     1981 gacgcagaga cgagcgatgc gcacccgcga gagggtcctg caggccgcgg ccggcgagat
     2041 agtacggtcc gggtaccacg ggaccgccct ggtccgcgtg gcagcacgcg cgcacgtgac
     2101 actgggagcg gtgagcttcc atttcccgac gaaacaagcc ctcgtccagg aggtgtacct
     2161 ggacggcgtg aagcgcacct ccgaggcagt cgaagccgag gtgggagaag acacagagcc
     2221 cctgcagggc ctggccaacc tcactctgcg gctcgcctca ctgctcatcg acgatgatct
     2281 gacggtactc gcctgcagcc gactcagccg tgacgacccg acggggcact tcgcgtggcg
     2341 cgacacctgg cgcggtcatg tggccagact ggcggaccgg gcatgcagca gccccggcag
     2401 caccgtgaat tgttcgagaa aaacccttgg ctttctcgtg cactgcctgc tggcgggaac
     2461 ggaggtgtgg gctgttcatg ccgacgccga gcgccatgcg gctctgagcc acctggccgc
     2521 ggcatggcag caggccatgc ctggcggtcg catggacacc gagggctagc ggatcaccct
     2581 gcacctggtc aacgggcggt ccagcccccg tcgacgggaa ccgctgctgc cgtgatgaag
     2641 gacgagcgat ccgagcagag ccataccgcg gcctgtgcca cctcccgcgg cgcggcgagc
     2701 cgctgctgga tcgcgcgttc gacgaaaggg ccgaacaaat cgggcgtgcg ggccagcacc
     2761 tcctgcatca gctccgttcc cgtactcccc acgacgaggg cgttgacgcg gatgccgtac
     2821 gcgccgtact cgtcggccgc ggcccgggtc aggcctatga ccgcgtgctt ggctgcgatg
     2881 taaggggctg cgactccggt ggcgcgcaca cctgcaacgc tggatgtgtt gacgatggcg
     2941 ccgcccgtac cagcggccag catcgcggtg atctgcgcgc gcatcgcgtt ccagacaccg
     3001 cgctggttca ccccgatgat ccggtcgtac tcgtcgtcgc cgatctcgtg gaaggccgtg
     3061 ccggtggagg tccatccagc gttgttgaag gccgcgtcga gccgcccgaa ggtgtcgacc
     3121 gccttctcga ccacgtcgcg catgtcctgg gggcgggtga cgtccccagg ggccgcgagc
     3181 gcccgcccgc cggcggctcg gatctcggcg ccgagccgct cgaggtgccc cgcgcggcgc
     3241 gcggtcagca ctacggctgc gccttcggct gcgaacaggc gtgcggactc ggctccgatc
     3301 ccgctcgaag cgccggtgat catgactacc ttgtcctgca gcagaggttc gttcaccacg
     3361 gaaaagcccg ccaatcacac acgaggaccg aacaagtggg cgtgttcttc cgcccacgac
     3421 gagaaggacg tagcgggtcg cccgagaaga tcgccgacgt caggagtcgt ctcctccttg
     3481 gcaccggcgc gctggcgttc cgcactggcc gtcaaggccc gcaccatcac ctcgggatac
     3541 cggcgacgcc agcgttcctg agcctgggcg atcgtcagtc cagcgcatgt cagtcgacgc
     3601 cccaggacct cgccgagctg cgccgcctgg tcgcggaccg agatcgcccg gggacccgtg
     3661 agcgcatagg tccggccgtg gtgaccgccc tcgagcagga cgcgcagcgc gacctgtgcg
     3721 atgtcggagg gtgcgatgca ggcgttgcgg gaggtggggt ggagcgctcg cacggtggca
     3781 tcccggcgaa tgtcgggcgc ccaggccagg gcgtgggtca tgaaggcacg gggacgcagg
     3841 atcgtccagg ggatgccgca ttgccggatg cggtcctctg ctgcgcgctg ccacgaggtg
     3901 atgaagtctt gagcccggag atcggcgacg gcgagcgcgg agagcttgac caggtgaccg
     3961 acgcccgcgg ccacggccgc ggtgacgatg ttggcgtcat ggtccggacg cagcgggtcg
     4021 ttggtgatga ttaatacggc gtcagcgccc gcgaagacct cggtcaggcg ggcgatatct
     4081 tcgaagtcgg cccggatgac acgtccggcg agcgccgcac cggccggatc ccgggtgagg
     4141 aaaactccgt ggcaggaaac ctcggacgcc aataaccccg ccacgtgccg gcccaccgtg
     4201 ccggtggcac cagttacgac gatacgccgg tcggctctgc ccgggcagct ctctgctgtg
     4261 ctgtgggaac cggcggccat ctactcggtg cacccacgcg cggggtcgac gacaaggcgg
     4321 gcatgggcct cctccgaggt gattcccgga aggaggatct gccacatctc acaggtgcgg
     4381 tccataaggt cggcgcggca gctgaccagt tgggagtaca gctgcacacc agtgcaggcc
     4441 ccgaccacga acctggccaa agccgccgga tccacctccg ggcgcagctc gccgttgtcc
     4501 cgggcctcct gcaggtaccc ggccatgatc gaggcccagt tgttgaagga ggtggggtcg
     4561 ctcatgtcgt gactccgctg ttcgaccgcg agccgaaccc cagcccgcag aagcggatcg
     4621 agctgcagac ggcgggccca caccatggtt atgtcgatga catgctgcac cccctccgac
     4681 tgcagtagcg gttcgatggc ctgcggctga ctgttcatca ccgcctcggc cacaccccgc
     4741 ttgttgccgt agtggaagta caaggctccc agcgtcagcc ctgcccgcct cgcgatgtcg
     4801 gcgacgttgg tccccctgta gccgtgttcg tcgaacagtt cggccgctgc catgagtagc
     4861 cgttggcggg tatgcgcggc ccggccttgc ttcaggtcag acacttctca cctcgcctac
     4921 atcgacaaaa aataattttt cttttaatct taccatccgc atcgctcccg cggtaggcca
     4981 acgcagcgta aggagtccca gtgtccgcga ccttcgccga cagaccaggc accgcggtgc
     5041 cccagcacat ggtgcacaag cacactcaca ccgaggtctt actgaccggg tggtccgcgc
     5101 acgccgacga tgccttcacc gtcacggccc gatggccgcg cgctcacagt ttctaccgcc
     5161 cccgcgggca ctacgaatcc ttactgttcg cggagaccgt gagacagact ctgccgctgc
     5221 tctcccacga ggccttcgga gtacccttcg gccatcagtt cgtatggagc gatctgtctt
     5281 tcggcgtggc ctatgacgcc ctatgggcaa gcgaccggac gatggacctg acactcaccg
     5341 tcgagtgcag cgaggtcacc cgccgccgcg ccggcttctc ctccgcgcgc gtaagcgtgt
     5401 gcgcgtcaac gaacacaact accgtcggac acgctcggac ccgcttctcc gtccacagtc
     5461 ccgatgtcta tcggcggctg cgcgccggac gccatgacac ggccgcggcc cgcgcaagcg
     5521 cactgcgccc cacccccgga gtcctccccg ccagtgtagg gcggcacctg ccccaggacg
     5581 tcgtcctcgc ccccaccgtc cactccgacg tctggcggtt gcgtgtggat ctgagccatc
     5641 cgatcctgtt cgaccaccct gtcgaccacg ctcctggcat gctccttctt gaagcaaccc
     5701 gccaagcagt gctctccgtc caccccacag gtgacgccgt cgtcacgagc atggccgccc
     5761 ggttccatcg ctacgtggaa ctggaccgcc cagcgtgggt ccgcctcgcc tccggtaccc
     5821 atggttcctt cagcgtgagc atcgaccagg acgaacagac ctgcttcgaa gccgaggcga
     5881 cgaccaagac cgtgtcgcac gggtctgtca aacgttcggt gtaaccaggg tggttgaggt
     5941 tactggcggg ccgccgacag gcggccgtcg aaggtgatat caaaggcgtt cagcacggtc
     6001 ttccaacggc tggtccagcg ggtctggccc ttgccggtgg tcagcccctt ggcggacagg
     6061 gagatcacca tctcgtccac gccggtcagg cgcttctgcc gcttcttgac gatcttcggc
     6121 tcgaaggagc cctcccggtc gcggggcacg gctatctcca ccgggccgac atcggtcagc
     6181 acggtcttgc tgcgggtgcc gttgcgtgag ttgccgccgt tcttcccagc cggatcatgc
     6241 ttgtcatagc cgaggtggtc ggtgatctca ccctccaggg cggactccag cagccgcttg
     6301 gtcagctgct gcagcagccc gccctcgccg gtcagctgca ggccctcggc ctgggcccgc
     6361 cccaccagct cgtcgatcag ccggtcctcc gcggccttgg cctgcggctc acccgactcg
     6421 acggtctcgg cctcggtcac gttctcactg gtcatcggtg catcttcctt gatcaggagt
     6481 tacaccgaac tttttacagt ccccttgggc gagttccggg gtcgtgcggt tggtcgggcg
     6541 acgaccggtt ggggtgcata gcggagcagg cacgggcttc gtgatcattg gggtgtccaa
     6601 gctcaacgat catgaggtgg cccatgcctg ccgctgtatc ttctcccatc ccaccggtgc
     6661 tggtgaagct ggggccgctg gatgtcagcc aagtcgctga cctgcgacct ttcctggacc
     6721 tggtgcccga cccgcgtgcg agacggggcc gctggtaccg gctgaccgcg gtccttctcg
     6781 tctgtgcctg cgcggccgtg tcgggagcca ggagcgtcga tgagatcgcc gagcacgttt
     6841 cctggctgat ctacgcccga agggttgcac cgcgctcccg ccggcgccgg ttgcgctgct
     6901 tccaccaggc cctgctcacg ctggtacatc tgcgcaccac cgctccgccg gccgaggtcg
     6961 ccgccggaca acgtttcaca gtccccgtgg cggcgaccga gtcgcggcct cgaatgagcc
     7021 gaactccggc tcgttcctgt gagatcgacg gggcctccct ggtgaaccag tccgcgtgtg
     7081 gggcgcgttc gcatcgacgt cgccggcagg actccggaga caagccgccg ggcccctgga
     7141 ggagagagag gcaccggctc gtgcttcggc gggcggcggt gttgtcagga ccggcggtcg
     7201 ccaccgaagg cggcgtcgaa ggaggcggtg gggggctcga agtcgaagcg tttgagcgcc
     7261 cgcagggctt cgggagcgcc ttggaggcgg ctcatccccg ggtcctccca ttcaacggag
     7321 acgggaccgt cgtacccgat ggaggacagc atgcggaaga cgtcctccca tggaacgtcc
     7381 ccgtgcccgg ccgagacgaa gtcccagccc cggcgcgggt cgccccaggg caggtgggaa
     7441 ccgagccgtc cgttgcgccc gtccagccgt ttacgcgcct ccttgcagtc cacatggtag
     7501 atccggtcgc ggaagtcgta gaggaacccg acggggtcga ggtcctgcca gacgaagtgg
     7561 ctcgggtcga agttgagccc gaaggcgggc cggtggtcca cggcctccag cgccctgtgc
     7621 gtcgtccagt agtcgtaggc gatctcaccg gggtggacct cgtgggcgaa ccgcacgcct
     7681 tcggtgtcga agacgtcgag gatcggcccc caccgttcgg cgaagtcggc gtatccgcgc
     7741 tccaccattt ccggcggcac aggggggaac atcgccacga ggtgccagat cgaggacccg
     7801 gtgaacccga tgacggtgtc cacgccgaga gcggcggcgg ccctggccgt gtcggccatc
     7861 tcggccgcgg cccggcgtct gacgccctcg gggtcgccgt cgccccagat gcggcccgga
     7921 agtatcgcct ggtggcgttc gtcgatgagc cggtcgcaca cggcctggcc gaccaggtgg
     7981 ttggagatgg cccagcatct cagtccgtag cgcgcgagga gctccctgcg gccccggacg
     8041 tagtcctggt cctccaatgc ccggtcgacc tcgaagtggt ctccccagca ggcgagttcg
     8101 agtccgtcgt agccgaagtc ccgggcaagg ccgcagacct cttccagggg gaggtcggcc
     8161 cactggccgg tgaacaaggt gaagggacgt ggcattgtcg cgtgtctcct tgccgtcaga
     8221 cgggtacggg ggtgtagctc gcgttcttcg ccgcgctctc ctcaactgcg gccagcaccc
     8281 gctggacctg cagtccttcg gtgaacgacg gtgcggggtc ggtgccggtg gcgatcgcct
     8341 gcacgagatc gtgggcctgg tgggtgaaag tgtgctcgta gcccagcgcg tggccggggg
     8401 gccaccacgc ctccaagtac gggtgctcgg gttcggtgac caggacgcgc cggaaaccgg
     8461 ccgtcgtggc cggctcagtg tggtcgtgga atgacagttc gttgaggcgt tcgaggtcga
     8521 aggccagcga tcccagctcg ccgttgatct ccacgcacag cgcgttcttg cggcccgccg
     8581 ccacccggga cacctcgaag ctcgcgaggg cgcccgaggc gagccgaccg gtgaacaggg
     8641 ccgcgtcgtc cacggtcacc ggtcccctgg cccgcggccc gtcgttcccc gtgagcatcg
     8701 cggcaaccag gggccgctcg gagacgaacg tctcggtgag ggccgacaca ccggccaacg
     8761 gctccgcgga caggtactgg gccagatcca ccgcgtgcgc gcccaagtcg cccagcgcgc
     8821 cggaaccggc cttctcgcgc gagaggcgcc aggtcagcgg gaactcaggg tcgacgagcc
     8881 agtcctggag gtaagtgacc cggatatggc gcagcgctcc gaggcggccc ccggcgatca
     8941 ggcggcgggc ttggacgatg gccggtaccc gacggtagtt gaagcccacc atcgccacct
     9001 ggccacgccg gctagccgcc cgcgcggcct ccaccatggc ctccgcctcc ggcacggagt
     9061 tcgccaacgg cttctcacac agcacatgtt tacccgcctc cagcgccgcg atggcgatct
     9121 cggcgtggct gtctcccggt gtgcagatgt cgaccaggtc gacgtcgtca ctgtccacga
     9181 cggcacgcca gtcggtcacg gcggctgccc agccttgctg ccgggccgcc gctccgaccg
     9241 ccgcttcgtc acggcccgag atcatcgcga gccggggacg cagtgggagc gggaacgcgt
     9301 gcctcaccgt tcgccacgcc tgcgagtggg cgacgcccat gaacgcgtag ccgaccatgc
     9361 cgatgcccag gtccggcgtg ggctcgccgt actctctgcg atcactgtgt ttcatcagat
     9421 gtactcctgg ttggccgggt ggggggaagg ctcagatgaa gccggtgggc aggtagtcct
     9481 ccacgttgtc cttggtgacg atcgccgagt agagcgtcag ggatgagggg atctccagct
     9541 cggccaggcc gctgacgccc ttgccctgcc cgagggcgcg ggcgaggtcg atcgcggagg
     9601 ccgccatggt cggcgggtag agcacggtgg ccttgagtac gctgtcgtcg gactggatcg
     9661 cttccatggc cgacttcgag cctgcgccgc cgaccatcac gaactcgtcc cggccggctt
     9721 gctcgatggc ccgcagcgcg cccacgccct ggtcgtcatc gtggttccac agagcgtcga
     9781 aatccttttg agcctgcagt agttgggcca tcttggcctg gccggactcg acggtgaact
     9841 cggctgcctg gcgggcgacc ttggtgatgt tcggatagtt gctgagcgcg tcgtcgaaac
     9901 cccgggtgcg ctgcttggtg agctccaggg tgtcgagtcc ggcgagttcg acgaccttgg
     9961 cgtccgcgac gtccttcagc cgctcgccga tgtaccggcc cgcgttgagg cccattccgt
    10021 agttgtctcc gccgatccag caccggtagg cctgggggga gtcgaatatc cggtccagat
    10081 tgacgacggg gatgcccgca cgcatcgcct caaggccggt ctgggtgagc gccttgccgt
    10141 cggccggcaa gatcacgagc acgtcgacct tcttgttgat cagtgtcgtg atctggccga
    10201 tctgcgtcgc cgtgtcgttg gacccctcgg tgatttccag cgtcacgtcc tcgtactgct
    10261 cggcccgccg ggtggcgttc tcgttgatgg cgttcagcca tccgtggtcg gcctgcgggc
    10321 cggcgaaccc gatggtgacc ggcttgccgg gcttgtccgc ggtctccggt gccgcggcag
    10381 cggactcatc gctggaggag gcgttgctcg tgcagccggt gacgagggcg ccggcaccga
    10441 tcgccgcgcc gaacagcact cttctgcggc tggtgaggtt tttttcaggc atgttgagtc
    10501 agcccttctc aggtgtcgtg cggggagggg agaggaccag gagcgggtgc ctggtcaggc
    10561 tccgccggtg cggcggagcg tgcggtgttg gacgaggacg gcggcgacga tgatcgcgcc
    10621 cttggcgatc tgctggacgt cgctctgcag gttgttgagc gcgaagatgt tggtgatcgt
    10681 ggtgaagatc agtacgccca gcacggaacc gacgatcgtg ccgcgcccgc cggtcagcag
    10741 ggtgccaccg atgatcacgg ccgcgatggc gtcgagttcg tacaggttgc cattggtgtt
    10801 ctgtcctgaa cctgacaata tgatcaaaag gaaggccgcg ataccgcagc acagacccga
    10861 gagcacgtac aggtagagac gctggcggcg gatgtcgatc ccggccagcc gggcggcctc
    10921 ggcgttcccg ccgaccgcga gcgtgcggcg gccgaaggtc gtgcggttca ggagcagcca
    10981 gcctagcgcg gtcaccgcac cgaagacgag caccagggga ggtatgccga gcacataggc
    11041 gtcgggggtg cccaggtcca ggacggcgtc caccgtgacg atctgggtgc ggccgtcggt
    11101 gatctgcagg gccagcccgc gtgcggaggc gagcatcgcc agcgtggcga tgaagggaac
    11161 catgccgccg tacgcgacga ggatgccgtt gaccaggccg catccgacac cgacgacaac
    11221 agcggtgaac aggattccgg tgaaaccgta ctcctgtgtc gcgacggtgg tcgcccagac
    11281 cgaggccagg gcgacgatcg cgcccaccga gagatcgatg ccaccgccgg tgatgacgaa
    11341 cgtcatgccg acggtcacca ctccgatgat cgacgcctgc gtcagcacca gttgcaggtt
    11401 cgagcccgcc aggaaggtgt cgggctcggt gaccccgccg acggcgacga ggatcgccag
    11461 cacgcccagc agggagaggt tgcggacgtc cgcctgccgg ccgagacgag ccagcgggcc
    11521 cggcggcctg ccgcccgcgg gcccaccgcg gagaggacgc ttgccacgac tggccggctg
    11581 gggcgccgcc cgccgcggag aggagactgg ctgctgtgtc acgaaggctc cgttccagga
    11641 gacgtggtgt cggcatggcc tgccatcaac aggtcgagaa tgcggtcttc gtcgaggtcc
    11701 agggccggtg cggcgtcgac cacccggccc tcgcgcagca ccaggacacg atcggcgagg
    11761 ccgaggacct cgggaagctc gctggagacg aggagaacgg ccagacccgc gtcggcgagc
    11821 cgcctgatca cgccgtaaag ttccgcacgc gctcccacgt cgacgccccg ggtcggctcg
    11881 tcgagcagga ggacgcggca gtcccgcagc agccagcgtg cgaggaccgc cttctgctgg
    11941 ttgccgcccg aaagcgtgcg tatgagcaca tccgggtcgt cgggacgcag ggacagctcc
    12001 cgggtgacgg ccttcgtcgc gacgcgctcg ccacgccggt ccaaccagcc cagccgcgcg
    12061 aagcgcgaga gggtggagac cgacacgttg cgggtgacgg attcaagctg gaaaagcccc
    12121 tgagccttgc gttcctcggg agccaggccc agtcccgccg ccacggccga gcgtacgctg
    12181 ccgggacgca gccgccggcc gtcgacgctc acctccccgg cgctggggcg acgcgccccg
    12241 tagatggttt ccaggatctc cgagcggccg gaaccgacca ggccggcgag gccgacgatc
    12301 tcacccgccc gcagttcgag gtcgagcggc gcgaactccc cctcccgggc caggccacgc
    12361 gtccgcagga cggccggcgc actctcccga ggtgcgggcc ggccggggaa aacgtgctcg
    12421 atctcgcgcc cggtcatcag ggcgatgatc tccctgtccg aggtctcctc caccgcaaac
    12481 cccccggcga cggaccgacc gttcttgagg accgtgaccc ggtccccgat gcgccggatc
    12541 tcctcaagac ggtgtgagat gtagaccacc gccactccgt cggccgtcag ttcgcggacg
    12601 atgcggaaaa ggttctccgt ctcgtcgggg tcgagcgccg cagagggctc gtccatgacg
    12661 atgagccgca cgtcgtggga gagcgcccgg gccatcgaga cgatctgccg ctgcgcggcc
    12721 gacaactccc ccacggcccg gctcgcatcg atctcctcat gcccgagccg ccgcagcagc
    12781 tccgccgccg cgacgcgggt gtcacggccg cggatcacaa acccggcggc cgtccgctca
    12841 tggcccagga agacgttctc ggcgacggac aacccctcca ccaggtccaa ctcctggtag
    12901 atcgtggcga taccgagccg catcgcggcg atgggagatc tcagcacgac ctcctcgccg
    12961 cgccaggtga ccgtgcccga gtcgggccgg tgagcgccgg cgagcacctt gatcagggtg
    13021 gacttgcccg ctccgttctg ccccagcagg cagtgcactt cgcccgcctc cacctgaaga
    13081 gtgacaccgt ccagggctcg caccccgggg aagaccttga tgatgtccga catcgtgagc
    13141 agaggtgatc gggccgtgtc accggcccgg tgagaggaaa cagacatagg caccacgagg
    13201 aatcccaacg gaaaggacat gccgcccccg cccgggcgcc tgccgccggg gactggggct
    13261 gggactgagg acgggtggga gagtcgagtc gcggaggtca ggcgggcgag aacagatggt
    13321 cgctgatgag ccgcgtggca ccgatgaccc cggccatgcc gcccagttca cccaggacga
    13381 tgggaaggtt ccccgtcgcc agcggaaggg agcggcgata gacctgggaa cgcacgcttg
    13441 cgagaagcgt gtggcccagt cccgtcacac cgccaccgat gacgaccatg ccggggttga
    13501 agaagctgac gagcccggcg atcacctgcc cgacccgttc cccgcccgtg cgggccatgt
    13561 ccagtgcgac cgggtcaccc gcggccgcgg cggccgcgag atcggcggag gtgagtcgcc
    13621 cggacgcctc cagtcgtacg gccaggtgcg ccgaacgacc gctgtgtgcg gcctcttcgg
    13681 cgtccctggc cagcgcggca ccgctgaagt gtgcttccag gcatccgcgg tttccgcacg
    13741 cgcacagccg cccctgcggg tccacctgga tgtggccgat gtctccggcg cacccggtga
    13801 cgccccggta cacctggccg ccgacgatga tgccgcagcc gatccccgtt ccgatcttga
    13861 cgcagaggaa gtcggcgacg gagcgggcga cgcctgcgtg ctgctcaccg aggcccatga
    13921 ggttgacgtc gttgtcgacc atgaccgagc acccgaactc ctggctcaga gcttcacgca
    13981 cgggaaaccc gtcccagccc ggcatgatgg ggggcgccac gggcacaccc tcggggaagc
    14041 gcaccggacc gggaacgccg atcccgaccc cgtcgaagcc ttccgccagc ccggactcct
    14101 tgagcttctc cgccatcgcg agcacctgct cgaacaccgc gacggggccg tccttgacgt
    14161 ccgtggagtc gttgaggtgg cccagcacct caagctcgcc gttggtgacg gccacgtcga
    14221 tggaggttgc gccgatgtcc acgcccagga agcgcagacc tggcgcgagc cgcacgctgt
    14281 gggatcgccg gccccctcgg gaagcggcga acccatcggt ggccacgagg cccgtctcca
    14341 gcagccggtc gatctcaaca gccagtttgg agcgggagag ctggatgcgt tcccccaatt
    14401 cggcccgtga gctgcgccca ccgtcccgca gcagacgcag caggtgtgcc tggtgagtat
    14461 tggccggccg agccgtcatc cgccgcacgg gcactcctca acgtcggtcg ctgcgcgttg
    14521 agacaccgcc cagcgagcga accctgacgg gctttcgccg agaagctagc agcgtacgcc
    14581 agccttagga agaagttgcg cggtatcgcc cgtaactttc gccaaccaga ggacgaagca
    14641 ccacgtcgcg tgccgaccag ctgcacagag caatcaacgt tccacgtcga tctcggcgtt
    14701 cgaggacact cacgggctgg tgatcgacag gccgagccgg tccgctcccc agggtctgca
    14761 cctttggcga ccgcctcgcg gaccggccga cctctcatcg gcgtgctcag ccgggcgagg
    14821 cgcgcgtgcc ggggcgccgg cgcacggcgt gcgcccgtgc gccggcgccc caccgcggat
    14881 cggaagctgg tcaggcgcca cagggcctcg gtgccgtacc cgtcaaaacg tcaagcacgc
    14941 gcgagccggg cccgtggcgg ccgtcgcgaa caccgcggcc ggtgttgccg tcacgctagg
    15001 cgtcctctac cgccgtccga cccacaagcc atgtggcacg ggacggccgg ttcgtcagtg
    15061 gaacgggccg ctgtagacgt tgagtgcggg ccggccgccc ggagccccgc gacgactcga
    15121 ccgccaattg ggagacgcga ctcgatcgct gcacagggca acgtcggcga ggtcgtctac
    15181 tgggttgatg tacgacgagc cggcggaggt gagcgtgccc gagatccggg ccggaatgga
    15241 catcggcaag acacaccacc acacagtggt gatcaacgcg gacggcggac ggtcgctgtc
    15301 ccgcagggtc cagaacgacg agtccgagct gttggaactg accggcgaca tcctcgcgat
    15361 atccaccgac gcgctgtggg cggtcgacct caaccagggg gcgctgcctt gctgaccggc
    15421 ctcctgctca gccacggccg gcccattgcc tacctgatcg ggaccgtcgg gaggccgtcg
    15481 ccctggacag gccgaacctc ggcggcaact ggttccaggt gcggcccgaa gtggccacga
    15541 agatgatcgc ggccagcatc tcgcggtccc ctcgccgacg atgtccccgc cctgcgggcg
    15601 aagatgacgt ccagggggcc tggaggagcg ggccagccgg ttcagcgggg cgtcggcagc
    15661 ctgtccagcg gtcggcgttc ctggccgtgc ccggtcaccc gccacaccgg ccggtcaggc
    15721 ccgtgcacgg tcaactgctg cagggtcgtg gtcgtcacga ccagttgccg gtgccgcaca
    15781 ggcggggcga tggccgcgag gtcgtggaag acggcctcgc gggtgtccgg tgcggcgcgg
    15841 cttctggtgg ggcggggcgg gggcagtgcc ttgtcgccgg atgactcgtt gagagcagtg
    15901 ttggggacgc tgggtcccgc ccggccacag ggagagaccg acgggatccg ttcagacagg
    15961 ggaggtaggg gtgtccgcat acgaggaagc cggcatcacc acaccggagc tgtgcgaatc
    16021 gtacgctcgg tgcgaggagg tgggacagcg gttgtccggg ctgctctgga cggccacgga
    16081 gtcgctgccc gccgaggttc ggccgcatgt ccgcgcgctc gtcgcccact ggcacacgac
    16141 cgacgacatc gccgacgagg gccgcctcgc cggccgtgag gcgcggctgg cgcagtggtg
    16201 cgccgattcg ctggccgagg tgcgcgcggg acacagtgag catccgctgc ggcgggcgtt
    16261 ggtgcacacc gtccgcagcc gggagtcgga catcgcactg ctggaggagt tcctggacgc
    16321 cacccggagg gacagcgcgg ccccgcccgc gttcggcaca gccgcggacc tgcggcgcta
    16381 cctgcggagt gtgaccggcg cgcccagcgg gctgacagcc cgctgctggc gccccgcccc
    16441 cgggaaggga cggtcgtgat atgcccggga acacgtgatc ggctgtcggc ggctcgcccc
    16501 caccgccgcc tgcccctggg cacccgcgcg aagacatcgc ggccgacggt gcccgttatg
    16561 cccctgggcc accccttgtc cggccggttt gcctactccg gtgaagggcc gcggtaggtg
    16621 ccgaaggtcc acagattgcc ctccgggtcc tgcaccgtgc acacgtacgc cacggcgccc
    16681 gatccgaacc gggtctcatg cggcgcttcg agaacctcgc cgccggcacc gaccacccgc
    16741 tggtgtactg cgtctacgtc gtcgctcacc acgtagaccg cgctggtgcc cgcccgcatc
    16801 cgcccgtgca cgctgtctgt gtgccgggtc gatccgaaca ccagcgcacc accgccgggc
    16861 cagcgcagct cggcgtgccc gatcccgccg tactcgtccg gcgcggcgat cacctccgtg
    16921 aagcccagca cgtcgaccag gaagcgcagc gccgccctcg tgtcgtcgta gtgcaggacc
    16981 ggccatacgg aggacgggga ggcatcaggc gacatgccgc tcatcgtagg tccgaaggca
    17041 gctacagccc agagcctccg gccaccggtg gaacgagcca ctctttggtg ccccggggct
    17101 ctgatcagtg ctcgtacaga gggaaaccga acagcgtacg gccggaacac tgcctcttcg
    17161 ccagtacacc gtgcccgcgg ccccggccgg tcggcagggt tggaccgtgc gaaggcttcc
    17221 agccagcgcc gctggtgggc gccgtcacgg tgtcgcggtg catgatgtgg ccggtcgcgg
    17281 tgaacccctc gccggtgtag agcgcctggg cggctggatt gccgtcgagt accgtgacct
    17341 cgcccctcgg tccggcggcg gcatgcgacg aaaccggcta ctgtcccgtc ggcctccgcc
    17401 accccaccca caaccggccg tcgaacagcc cctcctcttg agctgtccgc gcgggcgtca
    17461 aaaatgcctc gacaccagcg gagtcgcaca actcgtcaag acgcgcggca tcgtgaatcc
    17521 gcgcgaccgt ggcccagtca tcattggcat acggccggat ctcgatcttc acgaatggca
    17581 tgctcacaat ccacacggtc catccatagt cggcacagca tgttcacgcc accatcacgg
    17641 cacgtggcgg aagcgggacg accggaacag atcgggttgc tttctgacgg gcggagaggt
    17701 ccccgcgcag cgcggttccc cggcgcgtcg ctccggggaa ccgcgtgcga acggcatgga
    17761 cagccaccgg cctcgcgagc gggccggaag ggtggtcagc ggcagcagga gtcggaacag
    17821 caggtgtgga ccctgacgtc gtcgatgacg gggccgtggg cgctgttggg agtggtgctg
    17881 gcgaaggcga gggtagtggt cgggttgttg gcgacgaagg tgaactgccg agtcacataa
    17941 cccatgttgg accgggtctt gccggcggtg tcgaaggaga agtcctggaa gttctgcccg
    18001 tcgacgagcg ccctgccggt cttcagcggt gacgcgccgt cggggttgcc ggcgagggag
    18061 taggtgacgg tgtaggtctt gcccggggtg gtggtgaatg tctgtgccac ggtcgccggg
    18121 acggttgcgt tgaggtcgag ggactggtcg ccttcggcgg cctgccagaa tccggcgccg
    18181 atcaggtccg ccgcaccgga ggtgaccttc cacggcccca tggaggcgcc ggctgcgaag
    18241 ctctggaagc tgttcgccgc aaccgcgggg tactcgaagc tgccgtcgtc gaaccggctg
    18301 gcggtggggg ccgccgttgc ggttccggcg gcggcgaaca ggacggcggc cacggccgca
    18361 gtcgtgcagg aacgcgtgag cagcatgaag tcctcctggt cagagagggg gtggcagtct
    18421 ggtcgacttg ccggatcaaa tctcccctca cttcggatgc gtgccaagac cgggccaccc
    18481 gcgcaccgga gcacggggcg gatgcaccgg cctgtgcacg ccgaccggcc ggggcgcaag
    18541 cccccgaacg ccacctgcag tggcgtcggc gcaggcaagg acgcggagtg cccccgtttg
    18601 acgcggcagc gctgtcaggg cgtcggcacc cagggccacc tcgggcactg gtgaaagacg
    18661 gtgtccgagc gtcgaggccc ggtgggcgcc atgccgtcgg aggttgtcgc tcagtatctg
    18721 ctgacggacc tgctcggcgt ccggcacgcc aggggcggga gcggtgtggg agccgacagg
    18781 gcggcgtgcg gcggagttgc gcagtcaccg gtcgcagcgg tctgtggcgt ggatcatgcg
    18841 gatgggagtc tgctcggccg gccggcacag cagcaggtgg ttctcggccg ggtcctcccg
    18901 tacatccttg aaggcggcgt cgcgaccgcg ggcgtgggcg cgcagccggt accagcccgg
    18961 cctcggcgag ctggaggtag gtgcaggagc ggcggctgcc ccgtcctggc cgtggggcgc
    19021 gggcatggcc gaccgcagga gggacgactt gactcgcttc cggcggggac cgtcccccgc
    19081 gtgcatcgcc atgggatgta cgccgaggac ggtcccgtgg tgctcccgtc agagtgcgcc
    19141 gggatcagca gtggatgtag atgctccgcc agccaacggg cgcggggctc gatgcgtcgc
    19201 cccggaaggt gtagtgcgga ctcccttgac agttgcgggt gttgaacatg ctcgcgtcct
    19261 ggcccgtgtg gtcgaacctg taggacccgc ggtggccgag gctgagattg ctgcagccac
    19321 atctggtgac ctccgagctg gtgccggtgt agtgcgcacc ggaccagccc cggaaactgc
    19381 tcgcgaaggc cgctcccgtg ctcaccgcca ggacggcggc cgtcatggcc gcggtaacgg
    19441 tggtacgtac ggtgtgctgg ttgcgcatga gccctccttc gaaaggaatg aacactcttc
    19501 gagttcattt agctacacag agttgccttc cgtaagggcg ggcggatgta cgaccggcgc
    19561 gcggacgggc tcgcgcgctc ccactacccc acccccccta cgtgcgccgg gcacgcggtc
    19621 gacgccggaa ctcttgacaa ccctattggt ctggaccatt tttcctgggg tgcagtgtcg
    19681 ccgtgccacc cagaacacgc tctcccgcca cagtccccga catacggaga cagccatgga
    19741 ccgtccctcc gcacagacca gcagaacgag atccctccgc atccgcgcgg gagtcgcctt
    19801 cgcgacatgc gtcgctctcc tcgtcggcgg cgccaccact ctcgacggcc gcgacgccta
    19861 cgccgccgag ccgaacctgg tgcaaaacgg cggcttcgag tccggcctga gcggctggac
    19921 ctgctccgcc ggcagcggca cggccgtctc ctcccccgtc cacggcggca cggcggcgct
    19981 gaaggccaca cccgccggca gcgacaacgc caagtgcacc cagaccgtgg ccgtgcagcc
    20041 ggactcccag tacgagctga gcgcctgggt gcagggctcg tacgtctacc tcggcgcatc
    20101 cggcaccggc accaccgacg tctccacctg gaccccgggc ggctccggct ggcagcaact
    20161 gcgcacctcc ttcaccaccg gcccggacac cacctcggtc accgtccaca cccacggctg
    20221 gtacggccag agcgcctacc acgtggacga cgtctccctc gccggccccg gcggcgaccc
    20281 gggcgaaccc gaccccgacc cccagccccc ggccgcaccc gccacaccgg ccgtcggcgc
    20341 gaccacctcc tcctcggtca ccctgaactg gaacgccgtc gacggcgcca ccggctacac
    20401 cgtctaccag gacgggacca aggcgctgtc ggtgcagggc acctcggcga ccgtcaccgg
    20461 actggcggcc gccacctcct acgagttccg cgtcagcgcc gtcaacggcg cgggcgagtc
    20521 ggccaagtcc gcccccgtca ccgccaccac cgaccggacc gg
//
