LOCUS       NZ_FOSG01000007        24436 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces pini strain PL19, whole genome shotgun sequence.
ACCESSION   NZ_FOSG01000007
VERSION     NZ_FOSG01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces pini
  ORGANISM  Streptomyces pini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900114215.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:14:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,762
            CDSs (total)                      :: 5,677
            Genes (coding)                    :: 5,560
            CDSs (with protein)               :: 5,560
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 3, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 20 of 117
            Pseudo Genes (incomplete)         :: 111 of 117
            Pseudo Genes (internal stop)      :: 1 of 117
            Pseudo Genes (multiple problems)  :: 15 of 117
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 102625
            Orig. end                         :: 127061
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOSG01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24436
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24436
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24436
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14436](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14436)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(677..694)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    complement(702..716)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(1395..1739)
                     /locus_tag="BM237_RS12120"
                     /old_locus_tag="SAMN05192584_107104"
     CDS             complement(1395..1739)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146137.1"
                     /locus_tag="BM237_RS12120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107104"
                     /product="DUF3140 domain-containing protein"
                     /protein_id="WP_093849595.1"
                     /transl_table=11
                     /translation="MADISELELDALWDEFHAVVNMTSNELEAWLRTSVAGERTEELPE
                     QAGSERGRQVLAILRKRRTDLTDDDVAAMRDVVDTVGAERDRVRVAEAVRDSDWRHRMM
                     SLGHDPVRAS"
     gene            complement(1858..2319)
                     /gene="soxR"
                     /locus_tag="BM237_RS12125"
                     /old_locus_tag="SAMN05192584_107105"
     CDS             complement(1858..2319)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="soxR"
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719216.1"
                     /locus_tag="BM237_RS12125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107105"
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="WP_093849744.1"
                     /transl_table=11
                     /translation="MTDRDGRLAIGELAARSGLAPSALRYYEEMGLIHSERTTGNQRRY
                     PRTALRRVAFVRAAQQVGLSLEEVRAALDRLPVDRAPSATEWNAVARTWQLRIDARIGE
                     LERLKERLTGCIGCGCLSLRKCRLYNPGDAAGSQGPGARYLEGDPLPES"
     gene            2374..3102
                     /locus_tag="BM237_RS12130"
                     /old_locus_tag="SAMN05192584_107106"
     CDS             2374..3102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853718.1"
                     /locus_tag="BM237_RS12130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107106"
                     /product="transketolase"
                     /protein_id="WP_093849596.1"
                     /transl_table=11
                     /translation="MTTATPPHTPAPRSPENLGFEALPALMSLMTGDEKHDAAATSTLD
                     ALWVLYDRVLRVRPDRPGDPGRDRFLLSKGHGPMAYYAVLAARGFFPADWLPGFGSYES
                     PLGHHPDRTLVPGVEIGSGSLGHGLPLAVGTALGLRARRPAGPRVWVLVGDAELDEGSN
                     HEAIDFAGAAGLDGLHTLVIDNSSASHPPPGGIASRFTAAGWSALTVDGRDHEALYAAY
                     TRPHPGRPHAVVARVEPKHA"
     gene            3135..4085
                     /locus_tag="BM237_RS12135"
                     /old_locus_tag="SAMN05192584_107107"
     CDS             3135..4085
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986121.1"
                     /locus_tag="BM237_RS12135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107107"
                     /product="transketolase"
                     /protein_id="WP_093849597.1"
                     /transl_table=11
                     /translation="MDTMRERFASVVSRLLDEDPRLAVVLAEIGADGFRRAAGRHPDRV
                     VNVGIREQLLVGVGGGLALTGMRPVLHTFASFLVERPFEQLKLDFGHQGTGGVLVSAGG
                     SYDWPAGGFTHMAPGDVALLDTLDGWTVHVPGHPDEAETLLRRACAGGAGGNGGGDGNG
                     EDRVYVRLSAQTNARPRPVTGEGFLTVRRGGHGAPAVVAVGPLLDPVLEAVRGLDATVL
                     YAATVRPFDAAALRAAVAGPGAPEVVLVEPYLAGTSTAAAAEALADVPHRILGLGTARA
                     ELRRYGTAAEHLAAHGLDPRSLRERITSFTARAAV"
     gene            complement(4176..4766)
                     /locus_tag="BM237_RS12140"
                     /old_locus_tag="SAMN05192584_107108"
     CDS             complement(4176..4766)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944162.1"
                     /locus_tag="BM237_RS12140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107108"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_093849598.1"
                     /transl_table=11
                     /translation="MFPTSYDPTGHLLLTPEDREAPARVTRLRELGIGDAPVPEFDDFA
                     RRLARITGAPYAMVNFMDEHRQYFAGLYTPGSDRAVEPGPAQASPRAGRVMACDHGYCP
                     HVVVRRKALVLEDVCDYPRFAGNPVVDEIGIRSYLGAPLIDRTGMVLGTVCVVAQEPRP
                     WGRQGLETIKSTAAELVERIHRRERGVRATPVP"
     gene            complement(4747..5337)
                     /locus_tag="BM237_RS12145"
                     /old_locus_tag="SAMN05192584_107109"
     CDS             complement(4747..5337)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431328.1"
                     /locus_tag="BM237_RS12145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107109"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_093849599.1"
                     /transl_table=11
                     /translation="MDFVNDSDPFPTALKVLVAGGFGVGKTTFVGAVSEIEPLSTEELL
                     TQVSAATDSLEGVEDKTTTTVAMDFGRITLGARHVLYLFGTPGQERFWFMWDELSSGAL
                     GAVVLADTRRLDQCFAAVDYFERRGMGFVVAVNEFDGAHRYHPDEIRIALDLKPEVPVV
                     MCDARQASSGTQVLVSLVQHLIDSRSGHVPHVV"
     gene            complement(5315..5689)
                     /locus_tag="BM237_RS12150"
                     /old_locus_tag="SAMN05192584_107110"
     CDS             complement(5315..5689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152747.1"
                     /locus_tag="BM237_RS12150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107110"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_093849600.1"
                     /transl_table=11
                     /translation="MPEPEEGLWLDDAAGRLVRPYTVSNGRTRPTADFNLLTMVRSTGT
                     EPQSYLGPDHAQVLSLCDGPMTVAEIAAHVRLPAVVTKVLLSDLVDCGAVTTRAPMQMG
                     ADPTDRGLLEAVLHGLRKRL"
     gene            complement(5693..6109)
                     /locus_tag="BM237_RS12155"
                     /old_locus_tag="SAMN05192584_107111"
     CDS             complement(5693..6109)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236638.1"
                     /locus_tag="BM237_RS12155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107111"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_093849601.1"
                     /transl_table=11
                     /translation="MVSDAPIGRTTDLSWLLTGLVQRVPHTRSALLLSSDGLVKAAHGL
                     DTDTADHLAALASGLYSLARSAGIRFGSGGEARQVVVELDTALLFVSTAGSGACLAVLA
                     GSEADAAVLGYEMAMLVKSVRPYLATPARQPSGH"
     gene            complement(6154..7998)
                     /locus_tag="BM237_RS12160"
                     /old_locus_tag="SAMN05192584_107112"
     CDS             complement(6154..7998)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088398.1"
                     /locus_tag="BM237_RS12160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107112"
                     /product="sensor histidine kinase"
                     /protein_id="WP_093849602.1"
                     /transl_table=11
                     /translation="MPVASPPPASSPPGPPAPPAYGGAPNTPSTPNTPSAPHGTGQRGG
                     PARDTAADTALRHRMIRLAVLPAALVAVIAAAVVAYVLRALDGVRDGISAGPDSATVWG
                     VLGGALLLGCAVVVGAALSASSEARSTAERHARLRQAVAHGRSELQSMLHRLEKGEWPR
                     PPVHSPSPEPEDDSLGLVVHDVGQAQRAAELALVQAVALVRGNAGGSEEKVEVFVNLAR
                     RLQSLVHREIELLDELENEVEDPDLLKGLFHVDHLATRIRRHAENLAVLGGAVSRRQWS
                     RPVTLTEVLRSAIAEVEQYSRVKLVPPIEGTLRGHAVADVIHLLAELVENATVFSAPNT
                     QVLLRAQRVTAGLAVEVEDRGLGMPAAEQQRMNGLLADPGGIDVAELLQDGRIGLFVVS
                     SLARRHGITVQLRTNIYGGIQAVLVVPDALLGDEREEPRRRAAAAAEAGGHRPMPPGTA
                     RQETPRQETSRQEMPGQGAPHRQAPARPAYGQHAYGQQDHGQQAHGQEAARPLPSAAQP
                     AAHAPQSAPAPRAAPAPPPPEGHGGPQGAQGAQGDDRPQLPRRRRQEHLVPELRRSQRS
                     PGVSDEPEAEHTPGLMAAFRRGAGLAEGTDDDTPSRPG"
     misc_feature    complement(8193..8208)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(8231..8246)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    8232..8246
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(8260..8901)
                     /locus_tag="BM237_RS12165"
                     /old_locus_tag="SAMN05192584_107113"
     CDS             complement(8260..8901)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358576.1"
                     /locus_tag="BM237_RS12165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107113"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_093849745.1"
                     /transl_table=11
                     /translation="MDDGLFRLPAAEVAPGAMHLPGHLDGPAQRELLDACRAWSRPPAG
                     LRTVRMPRGGRMSVRQVCLGLHWYPYGYARTAVDGDGAPVKPFPAWLGRWARRAVEEAY
                     GKGPCTVPYDIALVNFYEGRARMGMHRDSDERSRAPVVSFSLGDTCVFRFGTPSGRGRP
                     WTDVELRSGDAFVFAGPSRLAYHGVPRVRPGTAPPGTGLRGRVNVTVRAR"
     gene            9118..9912
                     /locus_tag="BM237_RS12170"
                     /old_locus_tag="SAMN05192584_107114"
     CDS             9118..9912
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="BM237_RS12170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107114"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_093849603.1"
                     /transl_table=11
                     /translation="MTSETVEPALTGVRNFREVGGLPTADGRRVRQGLLYRSGHLAHAT
                     EEDAAFLSRLGLHTVFDFRNSADQALEGPDVELPGVRNVNIPLSDPAEGAEFWTMVREG
                     DLALLRSLLGDGQAEARMVASYRLMVKQRTAEHGRLLRELAEESVPALMHCAAGKDRAG
                     LSIAVTLLALDVEQDAIEADYLESNAPHHRYRIHRSPDAGGGMSPEVGELIAPLFEVRP
                     AYLHAAFDTITDTWGGVESYLSEGLGLTPGLRERLRGRLLDL"
     gene            complement(10001..11059)
                     /locus_tag="BM237_RS12175"
                     /old_locus_tag="SAMN05192584_107115"
     CDS             complement(10001..11059)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574768.1"
                     /locus_tag="BM237_RS12175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107115"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_093849746.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.8e-58, bitscore:
                     190.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTAVDTASVIELLERGRTLATPMLRAAVARLAPPMDSVAAYHF
                     GWIDAQGDPASGDGGKAVRPALALLSAEAAGAEPATGVPGAVAVELVHNFSLLHDDLMD
                     GDEQRRHRDTVWKVHGPAQAILVGDALFALAGEVLLELGTAEAAHATRRLTLATRKLID
                     GQAQDISYEHREKVTVAECLEMEGNKTGALLACATSIGAVLGGADEATADALEAYGHHL
                     GLAFQAVDDLLGIWGDPASTGKLPWSDLRQRKKSLPVVAALAGGGPAAERLGELLAADA
                     TKSQREFEDFSEEEFATRAGLIEEAGGREWTSQEAHRRHATALAALDGVDMPDRVRERF
                     AALADFVVVREG"
     gene            complement(11112..12539)
                     /gene="hpnE"
                     /locus_tag="BM237_RS12180"
                     /old_locus_tag="SAMN05192584_107116"
     CDS             complement(11112..12539)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612705.1"
                     /locus_tag="BM237_RS12180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107116"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_093849604.1"
                     /sec_met_domain="DAO (E-value: 3.7e-09, bitscore: 30.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGAPDPRAVVVGGGLAGTAAALRLADAGVATTLVESRPRLGGLA
                     FSFRRSGAAGELTVDNGHHVHLRCCTAYRWLLERIGASALAPLQPRLDIPVHDAARGRT
                     GRLRRAALPVPLHLGASLARYPHLSPAERLRVGRAALALGRLGRIDPGDPALDGQDFGS
                     WLRRHGQSPRAVRALWDLIGVATLNARAPDVSLGLAAMVIGTGLLSEPGAADIGWSRVP
                     LGHLHDTLAAAVLEKAGVRVVRQGRVRELDREPDGGWRVAVDSGARRTGRTLRAGTVVL
                     AVPQREAHRLLPEGALEEPERLLRIGDAPILNVHVVYDRKVLHRPFLAALGTPVQWVFD
                     RTAASGLRDAPGGAGSQYIAVSQSAAQDEIDLPVAALRDRYLPELARLMPAARGAKVRD
                     FFVTRERAATFAPVPGVGRLRPVARTGAPGLWLAGAWTATGWPATMEGAVRSGLTAARE
                     ALAALGRPHDDVFQEAA"
     gene            complement(12536..13507)
                     /gene="hpnD"
                     /locus_tag="BM237_RS12185"
                     /old_locus_tag="SAMN05192584_107117"
     CDS             complement(12536..13507)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470908.1"
                     /locus_tag="BM237_RS12185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107117"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_093849747.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.9e-57, bitscore:
                     188.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-68,
                     bitscore: 225.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRRSANAERAARQAPPSPQVFAAYHYCEAVTAGQARNFAYGIRL
                     LPTAQRRAMSALYAFSRRVDDIGDGPLETEVKRARLEETRNLLDLVRAGKVPDDATDPV
                     AVALADAAERFPIPLGGLDELIDGVLMDVRGRAYGTWDELREYCRCVAGAIGRLSLGVF
                     GTVPGAPGAERAPHYADTLGLALQLTNILRDVREDAAEGRTYLPREDLAAFGCDTSLDR
                     HAPPAGGDFAGLVRFEVGRARALFAEGLRLLPLLDRRSAACVAAMAGIYHRLLARIARD
                     PHAVLRGRVSLPAREKAYVALRGLSGLDARLAARTAPGGSTT"
     gene            complement(13513..14436)
                     /gene="hpnC"
                     /locus_tag="BM237_RS12190"
                     /old_locus_tag="SAMN05192584_107118"
     CDS             complement(13513..14436)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513262.1"
                     /locus_tag="BM237_RS12190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107118"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_245793588.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.3e-37, bitscore:
                     121.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.3e-39,
                     bitscore: 129.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPARDARSRTVLDKAARENFPVAPRFLPRARRDDLMAVYGCVRL
                     LDDIGDGDLPPGGADAALLGVDPDRADDRGALLDAFETELHRVFRTARDPGAAGRDVPR
                     HPLLYALVPTVRRHALTPEPFLALVEANRLDQKVRRYGTWEELLGYCELSANPVGRLVL
                     AVTGTTTPERVRRSDAVCTALQITEHLQDVAEDLALRDRIYLPAEDLERFRVTEADLAA
                     PTANASVRALVAWEARRAHELLNEGVPLVASVPGIPKILIAGFTGGGRAALRALRSARY
                     DVLGGAPRPGKAGVLRETAAVLGAAR"
     misc_feature    14461..14476
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            complement(14925..15758)
                     /locus_tag="BM237_RS12195"
                     /old_locus_tag="SAMN05192584_107119"
     CDS             complement(14925..15758)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568727.1"
                     /locus_tag="BM237_RS12195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107119"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_093849606.1"
                     /transl_table=11
                     /translation="MAVAEKSAAAASADKDTEDAEAVSAERRPTVIADGLHIVYRVNGG
                     ARGRGSATAALNRIIRRKPGGNVREVHAVKGVSFTAYRGEAIGLIGSNGSGKSTLLRAI
                     AGLLPAERGRVYTDGQPSLLGVNAALMNDLTGERNVILGGLAMGMSKTQIQERYQGIVD
                     FSGINDKGDFISLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDKKFQKRSEAR
                     IRELRKEAGTVFLVSHNNKSIRDTCDRVLWLESGELRMDGPTEDVMKAYEEFTRK"
     gene            complement(15745..16692)
                     /locus_tag="BM237_RS12200"
                     /old_locus_tag="SAMN05192584_107120"
     CDS             complement(15745..16692)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972239.1"
                     /locus_tag="BM237_RS12200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107120"
                     /product="ABC transporter permease"
                     /protein_id="WP_093849607.1"
                     /transl_table=11
                     /translation="MSETTHGGAIATGEPPRSPDDGLSPAELAAKYGLTVSGARPSLTE
                     YVRQLWARRHFILAFSRAKLMAQYSQAKLGQLWQVATPLLNAAVYFFVFGVLLGGREGV
                     PGGKGNYVPFLVTGVFVFTFTQTSVMSGVRSISGNLGLVRALHFPRASLPISFSLQQLQ
                     QLLYSMIVLGAILLGFGHYPKWTWLLVVPILALQLVFNTGLAMVMARLGSKTPDLAQLM
                     PFVMRTWMYASGVMFSLEYMIRERTSAPEWLVLAAQANPAAVYMDLMRFALIDGYTPAD
                     LMPYAWALAAGWAVVIGVGGFVYFWKAEERYGRG"
     gene            complement(16790..17698)
                     /locus_tag="BM237_RS12205"
                     /old_locus_tag="SAMN05192584_107121"
     CDS             complement(16790..17698)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639276.1"
                     /locus_tag="BM237_RS12205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107121"
                     /product="glycosyltransferase"
                     /protein_id="WP_093849748.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.6e-11,
                     bitscore: 36.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEGARSSSGRPLTLGAVVLTMGNRPEELRALLDSVAKQDGDPVQ
                     VVVVGNGAPLPELPRGVRTVELPENLGIPGGRNVGIEAFGPGGSEVDALLFLDDDGLLP
                     NTDTAELVRRAFAADPELGIISFRIADPDTGVTQRRHVPRLRASDPMRSSRVTTFLGGA
                     NAVRTAVFQEVGGLPDEFFYAHEETDLAWRALDAGWMIDYRADMVLHHPTTLPSRHAVY
                     HRMVARNRVWLARRNLPLPLIPLYLGVWLLLTLARRPSRPALRAWLGGFREGWTTPCGA
                     RRPMKWRTVWRLTRLGRPPVI"
     gene            complement(17713..18498)
                     /locus_tag="BM237_RS12210"
                     /old_locus_tag="SAMN05192584_107122"
     CDS             complement(17713..18498)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962488.1"
                     /locus_tag="BM237_RS12210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107122"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_093849608.1"
                     /transl_table=11
                     /translation="MSKPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREISLRWTRHLV
                     NTRITPNQLTYLMVVAGVAAGAVLLVPGPAGAVLAALLIQFYLLLDCVDGEVARWRKQT
                     SITGVYLDRVGHYLAEAALLVGFGVRAADVFRAEGASANWLWAFLGTVAALGAILIKAE
                     TDLVDVARSRSGLPAVKDEAAVPRSSGLALARRAAAALKFHRLVGGVEASLLILAVAVA
                     DAVHGGLFFTRLGVAVLAAVAVLQTLLHLVSILASSRLR"
     gene            complement(18476..19537)
                     /locus_tag="BM237_RS12215"
                     /old_locus_tag="SAMN05192584_107123"
     CDS             complement(18476..19537)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413836.1"
                     /locus_tag="BM237_RS12215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107123"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_093849609.1"
                     /sec_met_domain="Fe-ADH (E-value: 6.2e-21, bitscore: 68.7,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 5.6e-08, bitscore:
                     26.3, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLATLLVDQRISASGKLAIAISG
                     GSGAALRERFAPALPGADWYEVGGGTLDNAIKLADAMKSGRYDAVVGMGGGKIIDCAKF
                     AAARIGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAIVIDLDVIREAPIRF
                     VRSGVGDVISNISAVADWELSHKVTGESIDGLAAAMARQAGEAVLRHPGGCGDDEFLTV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPKRAAAHGEQCGLGAAFAMHLRG
                     AEEQTALIVEVLRRHGLPVLPGEIGFDEDEFVRAVEYAPQTRPGRYTIIEHLDLSTDQI
                     RDAYADYVKAVSS"
     gene            complement(19525..20274)
                     /locus_tag="BM237_RS12220"
                     /old_locus_tag="SAMN05192584_107124"
     CDS             complement(19525..20274)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069707.1"
                     /locus_tag="BM237_RS12220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107124"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_093849610.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 4e-11, bitscore:
                     37.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDPAGEGTTTVLDLTLGN
                     FREVGLTEAAVVVGYRKEAVHERRAALEKKYGVKLHLVDNDKAEEWNNAYSLWCARDVI
                     KEGVILANGDTVHPVSVEQTLLDARGKGQRIILALDTVKKLADEEMKVVTEPARGVRRI
                     TKLMDPADATGEYIGVTLIEGDAAADLADALKATYERDPQLYYEDGYQEMVNRGLTIDT
                     AAIGDVKWVEIDNHDDLNKAREIACQY"
     gene            complement(20271..22184)
                     /locus_tag="BM237_RS12225"
                     /old_locus_tag="SAMN05192584_107125"
     CDS             complement(20271..22184)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="BM237_RS12225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107125"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_093849611.1"
                     /transl_table=11
                     /translation="MSTAILTGPPVAGAPLEGGLRSLGFDVRVAEDTAGVEAALAAVPA
                     GERVALVDPRFVGHTHSLRLALTDPRFPAAAIPGALAVQPTARAALARAVSAVSAAAAP
                     SARTAPSASGGVARTAAPEPAVLPDRAAAALEEDGRGPAVHRPELGVLVAAVPADGAER
                     AEAERAVAAVDEERVRLRSAVKSRDGFFTTFLVSPYSRHLARWCARRGLTPNQVTTASL
                     LTALIAAACAATGTRGGFVAAGVLLIASFVLDCADGQLARYALRYSTLGAWLDATFDRA
                     KEYAYYAGLALGAARGGDDVWALALGAMVLQTCRHVVDFSFNEADHYRRDGGREREGEP
                     AAGSADPAAALSGRLDRVGWTVWARRMIVLPIGERWALIAVLTALTTPRTTFTVLLIGC
                     AFAACYTTAGRVLRSLTRKGVRTDRAVRALAELADSGPLAEGVARAAASRTRGVRGGRP
                     SAFTAPAPALLGSAALVAAALWAPVGPWLPAAALGYAVLSGLAVARPPAGALDWLVPPL
                     FRAAEYTTVLVLAARSDAAGALPAAFGLVAAVAYHHYDTVYRIRGGTGAPPHRLVLAIG
                     GHEGRVVAVTAAAALWAAGQGFTIALTALAGALALTVLTESVRFWVSSHAPAVHDETGE
                     PA"
     misc_feature    complement(22364..22377)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.91"
                     /tool="antismash"
     gene            22474..23481
                     /gene="galE"
                     /locus_tag="BM237_RS12230"
                     /old_locus_tag="SAMN05192584_107126"
     CDS             22474..23481
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-207). E-value:
                     2.7e-10. Score: 31.7. Matches aSDomain:
                     nrpspksdomains_BM237_RS12230_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016907926.1"
                     /locus_tag="BM237_RS12230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05192584_107126"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_093849612.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.1e-16, bitscore:
                     54.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.1e-12,
                     bitscore: 39.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLVTGGVGYVGAHVARAMAEAGEEVVVLDDLSSGLPERLPPGV
                     PLVRGSVADRGLLDRTIAGHGVTGVVHLAAKKQVGESVEHPLTYYRENLYGLTVLLEAV
                     VAAGVRRFVFSSSAAVYGMPDVDTVTEDTPCVPMNPYGETKLAGEWLVRAAGRAHGLST
                     ACLRYFNVAGAARPELSDVGVSNVIPMFFDALTRGEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAEAHLAAARRLAGLPAGEDLTVNVGTGEGVSVRELAGLVAETTGIREPAPVVAPRR
                     PGDPARVVASAGRIGVELGWAPRYGVREMVASAWAGWRPRGADGLQREGAAFPE"
     CDS_motif       22477..22563
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM237_RS12230_0001"
                     /evalue="4.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="BM237_RS12230"
                     /protein_end="30"
                     /protein_start="1"
                     /score="19.5"
                     /tool="antismash"
                     /translation="TWLVTGGVGYVGAHVARAMAEAGEEVVVL"
     aSDomain        22669..23094
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM237_RS12230_NAD_binding_4.1"
                     /evalue="2.70E-10"
                     /label="BM237_RS12230_NAD_binding_4.1"
                     /locus_tag="BM237_RS12230"
                     /protein_end="207"
                     /protein_start="65"
                     /score="31.7"
                     /tool="antismash"
                     /translation="GVTGVVHLAAKKQVGESVEHPLTYYRENLYGLTVLLEAVVAAGVR
                     RFVFSSSAAVYGMPDVDTVTEDTPCVPMNPYGETKLAGEWLVRAAGRAHGLSTACLRYF
                     NVAGAARPELSDVGVSNVIPMFFDALTRGEAPRIFGDD"
     misc_feature    complement(23550..23564)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    24194..24208
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
ORIGIN
        1 gcggcgcctg ctgaacctgc ggctgcgcta cgaggccacc cacgacgcgc tgaccgacct
       61 gcccaaccgc accctgttct tcgagcggct ggagcacgtc ctgtcccccg gctccggcac
      121 cacccggatc ggcctgtgct acctggacct ggacggcttc aagacggtca acgacagcct
      181 gggccacgcg gtcggcgacc agttgctggt gaacgtggcc gagcggctgc agagctgtgt
      241 ggcctcgccg cgccacatgg tcgcgcggat cggcggcgac gagttcgtgg ccctggtcag
      301 cgaccccgcc tcgcgctcgg aggtgaccga cctggcccgg cgggcgctgg acgcgctgtc
      361 cggcccgatc ccgctggccg gccgggagtt gccggtgcgc gccagcatcg gtgtggtgga
      421 gggcccggtc ggggagctga ctccggcgga ggtgctgcgc agcgccgaca tcaccatgta
      481 ccgggccaag gccgggggcg gcaaccgcta cgagctggcc gaccccgact gcgacgcccg
      541 caccatcagc cgccacatgc tgaccaccca tctgcccgcg gcgctggagg gcgaggagtt
      601 cttcatcgag taccagccgc tggtgcggat ggaggacggc agcgtggagg gcgccgaggc
      661 cctggtgcgc tgggcgcatc cgctccacgg ggtgctgggc ccggaccgct tcatcccgct
      721 ggccgagcac accgggctga tcgtgccgct gggccgctgg gtgctggagc aggcggtgcg
      781 gcaggcgtgc gagtggcagg tgcgcggcat cggcggcacc cagccgctgc gggtgaacgt
      841 caacctctcg ccgcggcagc tgcaccaccc ggagctggtc tccgagaccg tggcggtgct
      901 ggagaacgcc gggctggacc cggcctcgct ctgcctggag gtcaccgaga gcgccctgat
      961 ccgcgccgac gacgcggagc tgaagccttt acgccgactc gccgacctgg gggtgcggat
     1021 cgccctggac gacttcggaa ccggctactc gaacctggcc agtctgcgca ggctgcccgc
     1081 gaccaccctg aagctggacc gctccttcac ccggggcctg cagcaggacc cggccgaccc
     1141 ggtcgacctc aaggtcgtgg aggggatcgt ctcgctggcg cacgccctgg agctggccgt
     1201 gaccgtcgag ggcgtggaga ccgcggccca ggccgaccag ttgcggaagc tgggctgcga
     1261 ctccgcccag ggctggtact acgcccgccc cggcccgccc gagcgcctgt cgtcgcgggc
     1321 gctgccgctg gccgccgggc agtgagggac gggccgggcg cacggcaccg cgcccggccc
     1381 ggaccgcacc gcggtcagga cgccctgacg ggatcgtgtc ccagcgacat catccggtgg
     1441 cgccagtccg agtcccgtac cgcctcggcg acgcgcaccc gatcgcgttc ggcgccgacg
     1501 gtgtcgacga cgtcgcgcat cgccgcgacg tcgtcgtcgg tgaggtccgt gcggcgcttg
     1561 cgcaggatcg ccagcacctg ccgtccccgc tcggagccgg cctgctcggg cagctcctcg
     1621 gtccgctctc cggcgacgct cgtcctgagc catgcctcca gttcgttcga cgtcatgttc
     1681 accacggcgt ggaactcgtc ccacagagcg tccagttcca gctcggagat gtcggccatc
     1741 gtcaacctcc cggttctctc gcgccgcgcg agtgcccgca ccccggcacc cggaaacccg
     1801 ggccggtgcg cgggcactcg cgcggcggcc ccggcgcccg cgcaccggcc gcttccctca
     1861 ggactccggc agggggtccc cctccagata acgggcgccg gggccctgcg agcccgcggc
     1921 gtcccccggg ttgtacaggc ggcacttgcg caggctgagg cagccgcagc cgatgcaccc
     1981 ggtcagccgc tccttcagcc gctccagctc gccgatccgc gcgtcgatcc gaagctgcca
     2041 ggtgcgggcc acggcgttcc actcggtggc gctgggtgcc cggtccacgg gcagccggtc
     2101 cagcgcggca cggacctcct ccagggagag gccgacctgc tgggcggccc tcacgaaggc
     2161 gacccggcgc agggcggtac gcggatagcg ccgctggttg cccgtggtcc gctcggagtg
     2221 gatcaggccc atctcctcgt agtagcgcag ggcggagggg gcgagcccgg agcgggcggc
     2281 caactccccg atggcgaggc gtccgtctcg gtcggtcatg gcggcgagca taccgcttga
     2341 cctcaagcct ccttgaggtt gcagcctctt ggcatgacga ccgcgacacc accgcacacc
     2401 cccgcccccc gatcgccgga gaacctcgga ttcgaggctc tcccggccct gatgtccctg
     2461 atgaccggcg acgagaagca cgacgccgcc gccacctcca ccctggacgc cctgtgggtc
     2521 ctctacgacc gggtgctgcg cgtccgcccc gaccgccccg gcgaccccgg ccgggaccgc
     2581 ttcctgctgt ccaaggggca cggcccgatg gcgtactacg ccgtgctcgc cgcccggggc
     2641 ttcttcccgg ccgactggct gccgggcttc ggctcctacg agtcgccgct ggggcatcat
     2701 ccggaccgaa ccctggtccc cggcgtggag atcggcagcg gctcgctcgg gcacggactg
     2761 ccgctggccg tggggaccgc cctcgggctg cgcgcccgga gaccggccgg gccgcgggtg
     2821 tgggtgctgg tcggggacgc cgaactggac gagggcagca accacgaggc catcgacttc
     2881 gcgggcgccg ccggactcga cggcctgcac accctggtga tcgacaactc ctcggcctcg
     2941 caccccccgc ccggcggcat cgcctcccgt ttcacggccg cgggctggtc ggcgctgacc
     3001 gtcgacggcc gcgaccacga ggcgctgtac gcggcgtaca cccgcccgca tcccggacgc
     3061 ccgcacgccg tggtcgcccg tgtcgaaccc aagcacgcct gaccggcgcg gagaacacga
     3121 ggagaaccct ggacatggac accatgcgcg aacgcttcgc ctccgtcgtc tcccgcctgc
     3181 tggacgagga cccgcgtctg gcggtcgtcc tcgccgagat cggcgcggac ggcttccgcc
     3241 gggccgccgg acgccacccg gaccgggtgg tcaacgtcgg catccgcgag cagctcctgg
     3301 tcggggtcgg cggcggtctg gccctcaccg ggatgcgccc ggtgctgcac accttcgcct
     3361 ccttcctggt ggagcgtccc ttcgagcagc tgaaactgga cttcgggcac caggggacgg
     3421 gcggggtgct ggtgagcgcc ggagggtcct acgactggcc ggccggcggc ttcacccaca
     3481 tggcgcccgg cgacgtggcg ctgctggaca ccctggacgg ctggaccgtc cacgtgcccg
     3541 gccacccgga cgaggccgag acgctgctgc gccgcgcctg cgcgggcggc gcgggcggaa
     3601 acgggggcgg ggacggaaac ggggaagacc gggtgtacgt caggctgtcg gcgcagacca
     3661 acgcccgccc ccggccggtc accggcgagg gcttcctcac cgtgcggcgc ggcgggcacg
     3721 gggcgccggc ggtcgtcgcg gtcggcccgc tgctcgaccc cgtcctggag gccgtgcggg
     3781 ggctggacgc gacggtcctg tacgccgcca ccgtccgtcc cttcgacgcg gccgcgctgc
     3841 gggcggccgt cgccggcccc ggcgcccccg aggtcgtcct ggtcgagccg tatctggccg
     3901 gcacctccac ggccgccgcc gccgaggccc tggccgacgt cccgcaccgg atcctcgggc
     3961 tggggacggc gcgggccgag ctgcgccgct acggcacggc cgccgagcac ctggcggccc
     4021 acggtctgga cccccgctcg ctgcgggagc ggatcacctc tttcacggcc cgcgccgcgg
     4081 tctgacggcg cggcgcgggg ggccgggcgc ggagggcgga gggccggcgg gcagcccgac
     4141 cgccgggcgg gaccgctccg tgggcgcggg ggcgctcacg gaacgggcgt cgcccggacg
     4201 ccccgctcac gccggtggat ccgctccacc agttcggcgg ccgtcgactt gatggtctcc
     4261 agcccctgcc gcccccacgg gcgcggttcc tgcgccacca cgcagaccgt ccccagcacc
     4321 atgccggtgc ggtcgatgag cggcgcgccc aggtaggagc ggatgccgat ctcgtccacg
     4381 accgggttcc cggcgaagcg ggggtagtcg cagacgtcct ccaggaccag cgccttgcgc
     4441 cgcacgacga catgcgggca gtaaccgtgg tcacaggcca tcacccggcc ggcccggggg
     4501 gaggcctgcg caggccccgg ctccacggcc cggtcggagc ccggcgtgta caggccggcg
     4561 aagtactggc ggtgctcgtc catgaagttg accatcgcgt agggggcgcc ggtgatccgc
     4621 gccagcctgc gggcgaagtc gtcgaactcc ggaacgggag cgtccccgat acccagctcg
     4681 cgcagccgtg tcacccgcgc cggggcctcc ctgtcctcag gagtgaggag cagatggccg
     4741 gtggggtcat acgacgtggg gaacatggcc gctccttgag tcgatcaggt gctggacgag
     4801 ggagacgagg acctgcgtgc cggaactggc ctgccgcgcg tcgcacatca ccaccggcac
     4861 ctcgggcttg aggtcgaggg cgatccggat ctcgtcgggg tggtagcggt gggcgccgtc
     4921 gaactcgttg accgcgacga cgaaccccat gccgcgccgc tcgaagtagt ccacggccgc
     4981 gaagcactgg tccaggcgcc gggtgtcggc gagcaccacg gcaccgagcg cgccgctgga
     5041 cagctcgtcc cacatgaacc agaagcgctc ctggccgggg gtgccgaaca ggtagagcac
     5101 atgccgggcg ccgagggtga tccgcccgaa gtccatcgcg acggtggtgg tcgtcttgtc
     5161 ctccaccccc tccagactgt ccgtggcggc gctgacctgg gtgagcagct cctccgtgct
     5221 cagcggctcg atctcgctga cggctcccac gaaggtcgtc ttgccgaccc cgaacccgcc
     5281 cgccaccagg accttcaggg cggtcggaaa cggatcagag tcgtttacga agtccatgca
     5341 gcaccgcctc cagcagtcct cggtcggtcg ggtccgcccc catctgcatg ggggcccgtg
     5401 tggtcaccgc gccgcagtcc accaggtcgg agagcagcac cttggtcacc acggcgggca
     5461 accgcacatg ggcggcgatc tctgcgacgg tcatcggccc gtcgcacaga ctcagcacct
     5521 gggcgtggtc gggtcccaga tagctctgcg gctcggtccc ggtggaccgc accatcgtca
     5581 gcaggttgaa gtcggccgtc gggcgcgtac gcccgttgct gacggtgtac ggccggacca
     5641 ggcgtccggc cgcgtcgtcc agccacaagc cctcctcggg ttccggcatc cgtcagtgcc
     5701 ccgacggctg ccgcgccggt gtggccagat acgggcggac gctcttgacc agcatcgcca
     5761 tctcgtatcc gaggacggcc gcgtccgcct cgctcccggc gaggacggcc aggcacgcgc
     5821 cggagcccgc ggtcgagacg aacagcagcg cggtgtcgag ttcgacgacc acctgccgcg
     5881 cctctccgcc gctgccgaag cggatgccgg cgctgcgggc cagcgagtac aggcccgagg
     5941 ccagcgccgc cagatggtcg gcggtgtcgg tgtccagtcc gtgggcggcc ttcaccaggc
     6001 cgtcggagga cagcagcagg gcgctgcggg tgtgcgggac gcgctggacg agaccggtca
     6061 gcagccagga caggtcggtc gtccggccga tgggggcatc gctcaccatg atcgcgttct
     6121 tctccttggg gggggtgaga gccgtgcgcg gggctagccg ggccggctgg gggtgtcgtc
     6181 gtcggttccc tccgcgaggc cggcgccccg gcggaaggcg gccatcaggc cgggagtgtg
     6241 ctcggcctcg ggctcgtccg acaccccggg gctccgctga gaccgacgca gttcgggaac
     6301 gaggtgctcc tggcggcggc ggcgcgggag ctgcggacgg tcatcaccct gcgcgccctg
     6361 cgcgccctgc ggcccgccgt ggccctccgg gggcggtggt gccggtgccg cccggggggc
     6421 gggcgcggac tgcggggcgt gggcggcggg ctgtgcggcg gagggcaggg gccgggccgc
     6481 ctcctgcccg tgcgcctgct gtccgtggtc ctgctgtccg taggcgtgct gcccgtaggc
     6541 cgggcgggcg ggcgcctgcc gatgcggcgc cccctgcccg ggcatctcct gacgggacgt
     6601 ctcctggcga ggtgtctcct ggcgggcggt cccgggcggc atcgggcggt gcccgcccgc
     6661 ttccgccgcg gcggcggcac gccgccgcgg ttcctcccgc tcgtcgccca ggagcgcgtc
     6721 cggcacgacg agcaccgcct ggatgccgcc gtagatgttg gtccgcagtt gcacggtgat
     6781 gccgtgccgc cgggcgagcg aggagaccac gaagagcccg atgcggccgt cctgcagcag
     6841 ttcggcgacg tcgatcccgc cggggtcggc cagcagtccg ttcatccgtt gctgctcggc
     6901 ggccggcatg cccagtccgc ggtcctcgac ctcgacggcg aggccggcgg tgacgcgctg
     6961 ggcgcgcagc aggacctggg tgttgggggc ggagaacacc gtggcgttct cgaccagttc
     7021 ggcgagcagg tggatgacgt cggcgacggc gtggccgcgc agggtgccct cgatcggcgg
     7081 caccagcttg acgcgggagt actgctcgac ctcggcgatg gccgagcgca gcacctcggt
     7141 cagggtgacc gggcggctcc actgccggcg ggagaccgcg ccgccgagga cggcgaggtt
     7201 ctccgcgtgc cgccggatgc gggtggccag gtggtcgacg tggaagaggc ccttgagcag
     7261 gtcggggtcc tcgacctcgt tctccagctc gtccagcagc tcgatctcgc ggtgcaccag
     7321 ggactggagt ctgcgggcga ggttgacgaa gacctcgacc ttctcctcgc ttccgccggc
     7381 gttgccgcgc accagcgcga ccgcctggac cagtgccagt tcggcggcgc gctgggcctg
     7441 gccgacgtcg tggacgacga ggccgagcga gtcgtcctcc ggttcgggcg acgggctgtg
     7501 cacgggcggc cgcggccact cgcccttctc cagccggtgg agcatcgact ggagttcgct
     7561 ccggccgtgg gccactgcct gccgcagccg ggcgtggcgc tcggcggtgg aacgcgcctc
     7621 ggaggaggcg gagagcgccg cgccgaccac cacggcgcag ccgagcagca gcgcgccgcc
     7681 gagcacaccc cagacggtgg cgctgtccgg cccggcggag atcccgtccc gcacaccgtc
     7741 gagggcccgc agcacatagg cgacgaccgc tgcggcgatg accgcgacca gggccgcggg
     7801 caggacggcg aggcggatca tgcggtgccg cagggcggtg tcggcggcgg tgtcgcgggc
     7861 ggggcccccg cgctgtccgg tgccgtgcgg ggcgctcgga gtgttcgggg tgctcggggt
     7921 gttcggggcg ccgccgtacg cgggaggggc cggggggccg ggaggagagg aagcgggcgg
     7981 cggggaagcg acgggcaagg gagcggaact tccccttcct tgtcgcaccg cgcggctcgg
     8041 gggctcaggc atcgcagtcc tcggaacgtt gaggtcgtct cagcgggccg gtgcgctcac
     8101 cggctctcgt ggcaccgccg caacgctgat cgtcacccgg cgggggcacg ggcgaggtcg
     8161 gctcgttcgc ccccttcgcc ggcccccagc gggtgaaagc atcgtcacgc ctcgtgggga
     8221 agggcggcac gatcataacc ctcgtttgcc gggtgcgagt taccgtgccc ggaccgtcac
     8281 attgacccgc cctcgcagtc cggttccggg cggtgcggtg cccgggcgga cgcgcgggac
     8341 gccgtggtag gccagcctgg aggggcccgc gaacacgaag gcgtcgccac tgcgcagctc
     8401 gacgtcggtc cacggccggc cgcgaccgga cggggtcccg aaccggaaga cgcaggtgtc
     8461 accgaggctg aacgagacca cgggggcgcg ggatcgctcg tcgctgtcac ggtgcatccc
     8521 catacgggct cttccctcgt agaagttgac gagcgcgatg tcgtacggga ccgtacacgg
     8581 ccccttcccg tacgcctcct ccaccgcccg ccgcgcccac cggcccagcc aggccgggaa
     8641 gggcttgacc ggcgccccgt cgccgtccac cgcggtgcgg gcgtagccgt acgggtacca
     8701 gtgcaggccc agacagacct ggcgcaccga catccggccg ccccggggca tgcgcacggt
     8761 gcgcagcccg gcgggcggac gggaccaggc acggcaggcg tccaggagtt cgcgctgcgc
     8821 gggcccgtcc agatggccgg gcaggtgcat cgcgcccggc gccacctcgg ccgccgggag
     8881 ccggaacagt ccgtcgtcca cgccttccac cccacctccc ggcaccgggc cgacaccggt
     8941 cccggcacca ctgttccacc ggatctccac gcctccgccc cttcctcggg cggacccggc
     9001 ccttccgcgc gcccccatgc cgtagggtcg cagtggccgg tgcgggaccg cgcggcgggc
     9061 ggtgcaccgc ccgcgccgtc ccggccgccc ggagcgaggc cggaacaagg agtgcccatg
     9121 acatccgaaa ccgtggaacc cgcgctgacg ggggtgcgca acttccgcga ggtcggtggt
     9181 ctgccgaccg ccgacggccg gcgggtgcgc cagggtctgc tctaccgcag cgggcacctg
     9241 gcacacgcca ccgaggagga cgccgccttc ctctcccggc tcggcctgca cacggtcttc
     9301 gacttccgca actccgccga ccaggcgctg gagggcccgg acgtggaact gccgggcgtg
     9361 cggaacgtga acatccccct gtcggacccg gccgagggcg ccgagttctg gacgatggtg
     9421 cgcgagggcg acctggccct gctgcggtcc ctgctcggcg acggacaggc cgaggcccgg
     9481 atggtggcct cctaccggct gatggtcaag cagcgcaccg ccgagcacgg ccggctgctg
     9541 agggaactgg ccgaggagag cgtgcccgcc ctgatgcact gtgcggcggg caaggaccgg
     9601 gccgggctgt cgatcgcggt gacgctgctg gcgctggacg tggagcagga cgcgatcgag
     9661 gcggactacc tggagtccaa cgccccgcac caccgctacc ggatccaccg ctcccccgac
     9721 gcgggcggcg ggatgtcccc cgaggtcgga gagctgatcg cgcccctctt cgaggtccgc
     9781 cccgcctatc tgcacgcggc gttcgacacc atcaccgaca cctggggcgg ggtggagtcc
     9841 tacctctccg aggggctcgg tctcactccc ggtctgcgcg agcggctgcg cggccgcctg
     9901 ctggatctct gaccgccggg cctcacggct gtcccacggc cgcctcaggg cttcccggga
     9961 ccggcggccc ccgccggtcc cgtcggtccc gccggcggga tcagccctcg cggacgacga
    10021 cgaagtccgc gagggcggcg aaccgctcgc gcacccggtc cggcatgtcc acgccgtcca
    10081 gggcggcgag ggcggtggcg tgccggcggt gggcctcctg ggaggtccac tcgcggccgc
    10141 cggcctcctc gatcagcccg gcacgggtcg cgaactcctc ctcgctgaag tcctcgaact
    10201 cccgctggct cttggtggcg tccgcggcca gcagctcccc gagccgctcg gcggccggcc
    10261 cgcccccggc cagggcggcg accaccggca gggacttctt gcgctgccgc aggtcgctcc
    10321 agggcagctt gccggtcgac gccgggtcgc cccagatgcc cagcaggtcg tcgacggcct
    10381 ggaaggccag gcccaggtgg tggccgtacg cctccagcgc gtcggcggtg gcctcgtccg
    10441 ccccgccgag gaccgcgccg atggaggtgg cgcaggccag cagcgcgccg gtcttgttgc
    10501 cctccatctc caggcactcg gcgacggtga ccttctcccg gtgctcgtag gagatgtcct
    10561 gcgcctgccc gtcgatgagc ttgcgggtgg ccagggtcag gcggcgggtg gcgtgcgcgg
    10621 cctcggcggt gcccagttcc agcagcacct cgcccgccag cgcgaacagg gcgtcgccga
    10681 cgaggatggc ctgtgccggg ccgtgcacct tccacacggt gtcgcggtgg cggcgctgct
    10741 cgtcgccgtc catcaggtcg tcgtggagca gggagaagtt gtggaccagc tccacggcca
    10801 ccgccccggg gacgccggtg gcgggctcgg cgcccgcggc ctcggccgac agcagggcca
    10861 gcgccgggcg caccgccttg ccgccgtcgc cgctggccgg gtcgccctgt gcgtcgatcc
    10921 agccgaagtg gtaggcggcg acggagtcca tgggcggcgc gagccgtgcc acggcggcgc
    10981 gcagcatcgg cgtggcgagg gtgcggccgc gttccagcag ctcgatgacg ctcgcggtgt
    11041 cgacggctgt gtccgtcagg gtcctcgggg tcgccggggt cacggggtct cctctgcgtt
    11101 cggtgtcgtg ctcacgccgc ctcctggaag acgtcgtcgt gcgggcggcc gagggcggcc
    11161 agcgcttccc gggcggcggt cagcccgctg cgcacggcgc cctccatcgt cgcgggccat
    11221 ccggtggcgg tccatgcccc ggccagccac agccccggcg caccggtgcg ggcgacgggg
    11281 cgcaggcgtc cgacgccggg cacgggggcg aaggtggcgg cgcgctcgcg ggtgacgaag
    11341 aagtcgcgca ccttcgcgcc gcgtgcggcg ggcatcaagc gggccagttc gggcaggtag
    11401 cggtcgcgca gggcggcgac cggcaggtcg atctcgtcct gcgcggcgga ctgggacacc
    11461 gcgatgtact ggctccccgc ccctccgggc gcgtcccgca gcccagaggc cgcggtgcgg
    11521 tcgaagaccc actgcacggg ggtgccgagc gcggcgagga agggacggtg cagcaccttg
    11581 cggtcgtaga ccacatggac gttgaggatc ggcgcgtcac cgatgcgcag cagccgctcc
    11641 ggttcctcca gggcgccctc gggcagcagc cggtgtgcct cgcgctgggg tacggccagg
    11701 acgaccgtac cggcccgcag cgtccggccg gtacggcgcg cgccgctgtc caccgcgacc
    11761 cgccagccgc cgtccggctc ccggtccagc tcccgcaccc ggccctgccg gaccacgcgt
    11821 acgcccgcct tctccagcac ggcggcggcg agtgtgtcgt gcaggtgccc cagcgggacg
    11881 cgggaccagc cgatgtcggc cgcgccgggt tcgctgagca ggccggtgcc gatgaccatc
    11941 gcggccagcc cgagcgagac gtccggtgcg cgggcgttga gggtggcgac gccgatcagg
    12001 tcccacagcg cccgtaccgc acgcggggac tggccgtgac ggcgcagcca gcttccgaag
    12061 tcctgaccgt ccagggcggg atcgccgggg tcgatccggc ccaggcggcc gagcgccagc
    12121 gcggcccgcc ccacgcgcag ccgctcggcc ggggagaggt gggggtagcg cgccagggag
    12181 gcgcccaggt gcagcggcac gggcagggcc gcgcgccgca gccggcccgt cctgccgcgc
    12241 gcggcgtcgt ggacggggat gtccaggcgg ggctggagcg gtgccagcgc gctcgcgccg
    12301 atgcgttcca gaagccagcg gtaggcggtg cagcagcgca gatgcacatg gtggccgttg
    12361 tcgacggtca gctcgccggc cgcgccggag cggcggaagg agaaggcgag cccgcccagc
    12421 cggggcctgc tctccaccag ggtggtggcc accccggcgt cggccaggcg cagtgcggcg
    12481 gcggtgcccg ccagccctcc gccgacgacg acggcgcgcg gatcgggtgc gccggtcacg
    12541 tcgtgctccc cccgggggcc gtgcgggcgg ccagccgggc gtcgagcccg gacaggccgc
    12601 gcagggcgac gtaggccttc tcgcgcgccg gcagggagac ccggccgcgc agtacggcat
    12661 gggggtcgcg ggcgatgcgg gccagcaggc ggtggtagat gcccgccatg gccgccacac
    12721 aggcggccga gcggcggtcc agcagcggca gcagccgcag cccctcggcg aacagcgcgc
    12781 gggcgcggcc cacctcgaag cgcaccagtc cggcgaagtc cccgccggcg ggcggcgcgt
    12841 ggcggtccag cgaggtgtcg cagccgaacg cggccagatc ctcgcggggc aggtaggtgc
    12901 ggccctccgc ggcgtcctcg cgcacgtcgc gcaggatgtt ggtcagctgc agggcgaggc
    12961 cgagggtgtc ggcgtagtgg ggggcgcgtt cggcgcccgg ggcgcccggc acggtgccga
    13021 agactcccag ggagagccgt ccgatggcgc cggccacgca gcggcagtac tccctcagct
    13081 cgtcccaggt cccgtaggcg cggccgcgga cgtccatcag gacgccgtcg atcagctcgt
    13141 cgagcccgcc cagcgggatc gggaagcgct ccgcggcgtc ggccagggcg acggcgaccg
    13201 ggtcggtggc gtcgtcgggg acctttccgg cgcggacgag gtcgagcagg ttgcgggtct
    13261 cctccagccg ggcgcgcttg acctccgtct ccagcgggcc gtcgccgatg tcgtccacgc
    13321 gccgcgagaa ggcgtacagg gcggacatcg cccggcgctg cgcggtgggc agcagccgga
    13381 tgccgtaggc gaagttgcgg gcctgccccg cggtgacggc ctcgcagtag tggtaggcgg
    13441 cgaagacctg cggggagggc ggcgcctggc gcgcggcccg ctccgcgttc gcgctccgcc
    13501 tgaacaccgg gctcacctcg ccgctcccag gacggccgcg gtctcgcgca gcacaccggc
    13561 cttccccggg cgcggggcgc cgcccaggac gtcgtaccgg gcggagcgga gggcgcgcag
    13621 ggccgcccgc cctccgccgg tgaatccggc gatgaggatc ttcggtatgc cggggacgct
    13681 ggccaccagc gggactcctt cgttcagcag ttcgtgcgcg cgccgcgcct cccaggcgac
    13741 cagggcccgc accgaggcgt tcgcggtggg cgcggcgaga tcggcctcgg tgacgcggaa
    13801 gcgctccagg tcctcggcgg ggaggtagat ccggtcgcgc agcgcgaggt cctcggcgac
    13861 gtcctggagg tgctcggtga tctgcagcgc ggtgcagacg gcgtcggagc ggcggacgcg
    13921 ctcgggggtc gtggtgccgg tgacggccag gacgagccgc ccgacggggt tggcggacag
    13981 ctcgcagtag cccagcagct cctcccaggt gccgtaccgg cggaccttct ggtccagccg
    14041 gttggcctcg accagggcga ggaacggctc gggggtcagc gcgtggcggc gcacggtcgg
    14101 caccagggcg tacaacaggg ggtggcgggg gacgtcccgg ccggcggcgc ccgggtcccg
    14161 ggcggtgcgg aagacccggt gcagctcggt ctcgaaggcg tcgagcagcg cgccgcggtc
    14221 atccgcccgg tcaggatcca ctcccagcag cgcggcgtcg gcaccgccgg gcggcaggtc
    14281 gccgtcgccg atgtcgtcca ggaggcggac gcagccgtac acggccatca ggtcgtcccg
    14341 ccgggcgcgg ggcaggaagc ggggggccac ggggaagttc tcgcgcgccg ccttgtccag
    14401 gacggtgcgg ctgcgcgcgt cccgcgcggg ggtcaccggg ggccgcccgc tgccatctcc
    14461 gtcacctctg cgtctctcca accgacagtc ccgtccttcc cgaagcggcg gcgtccacgg
    14521 catccgtgtc cagcgtgtgc ggcccgccct gtgtccgcat gccaccgacg gcgtccgcga
    14581 caccacggaa tccgggaggg cctgcggtgc cggggtgccc gcggcgtcgg cgacgcctct
    14641 tcccccgcgg gcgccgcccg cgggatccgc gtacggaaca tcctatttcg ggcacgcccg
    14701 gggcatggtc cgctgctcgt ccgaccgggt gccggacgtc cggcgcaccg cccaccggca
    14761 ccggctcagc ttacgtcgtg cgggcgggcg ccccgccgca cgggtgggca cgtggccgga
    14821 cacggtccgg cccccgcgcc cgtcacgggc gcgggggccg gggaagccgc cgggaggccg
    14881 ccgggaggcc gccgggaggc cgccgggagc accggctgcc cgggctactt gcgggtgaac
    14941 tcctcgtacg ccttcatcac gtcctcggtc ggaccgtcca tgcgcagctc gccgctctcc
    15001 agccacagca cccggtcgca ggtgtcccgg atggacttgt tgttgtggct gaccaggaag
    15061 accgtcccgg cctccttgcg cagctcccgg atgcgggcct ccgagcgctt ctggaacttc
    15121 ttgtcgcccg tcgccagcgc ctcgtcgatc atcagcacgt cgtggtcctt ggcggcggcg
    15181 atggagaacc gcagccgggc cgccatgccg gaggagtagg tccgcatcgg caggctgatg
    15241 aagtcgccct tgtcgttgat gccggagaag tcgacgatgc cctggtagcg ctcctggatc
    15301 tgcgtcttgg acatgcccat ggccaatccg ccgagtatga cgttgcgctc accggtcagg
    15361 tcgttcatca gggcggcgtt gacgcccagc agcgagggct ggccgtcggt gtagaccctg
    15421 ccgcgctcgg ccggcagcag acccgcgatg gcgcgcagca gggtggactt gcccgagccg
    15481 ttggatccga tcagcccgat cgcctcgccg cggtaggcgg tgaagctgac gcccttgacc
    15541 gcgtgcacct cgcgcacgtt cccgcccggc ttgcggcgga tgatccggtt gagggccgcc
    15601 gtggcgctgc ccctgccccg ggcgccgccg ttgacgcggt agacgatgtg caggccgtcg
    15661 gcgatgacgg tcggccggcg ttcggcggag acggcctccg cgtcctccgt gtccttgtcc
    15721 gccgacgcgg cggctgcgct cttctcagcc acggccataa cgctcctccg ccttccagaa
    15781 gtacacgaat ccgccgacgc cgatcaccac ggcccacccc gcggccagcg cccaggcgta
    15841 cggcatgagg tcggcggggg tgtagccgtc gatgagcgcg aagcgcatga ggtccatgta
    15901 gacggccgcg gggttggcct gggccgcgag gaccagccac tccggagcgc tggtgcgttc
    15961 cctgatcatg tactccaggg agaacatcac gcccgaggcg tacatccagg tgcgcatcac
    16021 gaagggcatc agctgggcga ggtccggggt cttgctgccc agccgggcca tgaccatcgc
    16081 caggccggtg ttgaagacca gctgcagggc caggatcggc accaccagca gccaggtcca
    16141 cttcgggtag tgaccgaagc cgaggaggat ggcccccagg acgatcatcg agtagagcag
    16201 ttgctggagc tgctgcaggg agaaggagat gggcagcgag gccctcggga agtgcagggc
    16261 ccgcaccaga ccgaggttgc cggagatgga gcggacgccc gacatcaccg aggtctgcgt
    16321 gaaggtgaag acgaagacgc ccgtgaccag gaaggggacg tagttcccct tgccgcccgg
    16381 cactccctcg cggccgccca gcaggacgcc gaagacgaag aagtacaccg cggcgttcag
    16441 cagcggcgtg gccacctgcc acagctggcc cagcttggcc tggctgtact gggccatgag
    16501 tttcgcccgg gagaaggcga ggatgaagtg ccgccgcgcc cacagctgcc ggacgtactc
    16561 cgtcagggag ggccgggcgc cgctcaccgt cagcccgtac ttggcggcga gttcggccgg
    16621 ggacaggccg tcgtctggtg aacgcggggg ctcgcccgtc gcgatcgcac caccgtgcgt
    16681 tgtctcgctc acgttgaaac tttcgtcctc acagtgcgca gccgggatgg aatgagcgca
    16741 gcggggcccg gctgatgtca ccggacccga tgctctcaga cagagcttgt cagatgacgg
    16801 gagggcggcc cagtcgggtc aggcgccaca ccgtacgcca cttcatggga cggcgggcac
    16861 cgcacggggt cgtccagccc tcccggaagc cgcccagcca ggcgcgcagc gcggggcgcg
    16921 aggggcggcg ggcgagggtc agcagcagcc atacgcccag gtagaggggg atcagcggca
    16981 gcggcaggtt gcgccgggcc agccacacgc ggttgcgggc gaccatgcgg tggtagaccg
    17041 cgtggcggct ggggagggtg gtggggtggt ggagcaccat gtccgcgcgg tagtcgatca
    17101 tccatcccgc gtccagcgcc cgccaggcca ggtcggtctc ctcgtgggcg tagaagaact
    17161 cgtccggcag cccgccgacc tcctggaaga ccgccgtccg cacggcgttg gcgccgccga
    17221 ggaaggtcgt cacgcgcgag gagcgcatcg ggtccgaggc gcgcagccgc ggcacgtggc
    17281 ggcgctgggt gactccggtg tccgggtcgg cgatgcggaa gctgatgatg cccagctccg
    17341 ggtcggcggc gaacgcccgc cggaccagct cggcggtgtc ggtgttcggc agcagcccgt
    17401 cgtcgtcgag gaagagcagg gcgtccacct cgctcccgcc gggcccgaac gcctcgatgc
    17461 cgacgttgcg gccgccgggg atgcccaggt tctccggcag ctccaccgtc cgcacccccc
    17521 gcgggagctc cggcagcggg gcgccgttgc cgacgaccac cacctggacc gggtcgccgt
    17581 cctgcttggc gaccgagtcc agcagggcgc gcagctcctc ggggcggttg cccatggtga
    17641 ggacgaccgc gcccagcgtc agaggcctgc cggaggagga tcgcgcgccc tcggtcatgt
    17701 cgttcaccac cctcacctca gccggctcga cgccaggatg gacaccaggt gcagcagcgt
    17761 ctgcaggacc gcgacggccg ccaggacggc gacgcccagc cgggtgaaga acaggccgcc
    17821 gtgcactgcg tcggccaccg ccaccgccag gatcagcagg gacgcctcga cgccgccgac
    17881 cagccggtgg aacttcagcg ccgcggccgc ccggcgggcc agcgccagcc ccgaggagcg
    17941 gggcacggcc gcctcgtcct tcaccgcggg caggccgctg cgggagcggg cgacgtccac
    18001 caggtcggtc tcggccttga tcaggatcgc gcccagcgcg gccacggtcc ccaggaaggc
    18061 ccacagccag ttcgcggagg ccccctcggc gcggaagacg tccgcggccc gcaccccgaa
    18121 gccgaccagc agcgccgcct cggccaggta gtggcccacc cggtcgaggt agacgccggt
    18181 gatggaggtc tgcttccgcc aacgggcgac ctcgccgtcc acgcagtcca gcagcaggta
    18241 gaactggatc agcagggcgg ccaggacggc cccggccggg ccgggcacca gcagtacggc
    18301 gccggccgcc acaccggcga cgaccatcag ataggtgagc tggttgggcg ttatccgggt
    18361 gttcaccaga tgccgggtcc agcgcagcga gatctcccgc atgtacaggc gcccggccca
    18421 gtgctcaccg ctgcgccggt ccttcacccc ggcggggtgg acgaccgggc ggagttcagc
    18481 tactgacggc tttgacatag tcggcgtacg cgtccctgat ctggtcggtg gacaggtcca
    18541 ggtgctcgat gatcgtgtag cgcccgggcc gggtctgcgg cgcgtactcc accgcgcgca
    18601 cgaactcgtc ctcgtcgaag ccgatctcgc cgggcagcac gggcaggccg tggcggcgca
    18661 gcacctcgac gatcagcgcc gtctgctcct cggctccgcg caggtgcatc gcgaaggcgg
    18721 cgccgagccc gcactgctcg ccgtgcgcgg cggcgcgctt gggatagagc aggtcgaagg
    18781 cgtggttgat ctcgtggcag gcgccggagg cggggcggct gtcgccggcc accgacatgg
    18841 agatgccggt gagcaccagc ccctcggcca gcacggtgag gaactcgtcg tcgccgcagc
    18901 cgcccggatg gcgcagcacc gcctcgccgg cctggcgggc catggcggcg gccaggccgt
    18961 cgatcgactc accggtgacc ttgtgggaga gctcccagtc ggcgacggcg gagatgttgg
    19021 agatcacgtc gcccacgccc gagcgcacga agcggatcgg ggcctcgcgg atgacgtcga
    19081 ggtcgatcac gatcgcgatc gggttcggca cgccgtacga gccgcggccg gcgtcgttgt
    19141 cgagcgtggc gaccggggag cacaggccgt cgtggctgag gttggtggcg acggcgacca
    19201 gcggcaggcc gatgcgcgcg gcggcgaact tggcgcagtc gatgatcttg ccgccgccca
    19261 tgccgacgac cgcgtcgtag cggccggact tcatcgcgtc ggccagcttg atcgcgttgt
    19321 ccagcgtccc gccgccgacc tcgtaccagt cggcgcccgg cagggcgggc gcgaaccgct
    19381 cgcgcagggc cgcgcccgag ccgccgctga tggcgatggc gagcttgccg gaggccgaga
    19441 tgcgctggtc gaccaggagg gtcgccaggt cgtccagcgc accgggcctg atgtcgacga
    19501 cgaccggcga ggggatgagc cgggtcagta ctggcacgcg atctcccgcg ccttgttcag
    19561 gtcgtcgtgg ttgtcgatct cgacccactt cacgtcgccg atggcggcgg tgtcgatggt
    19621 gaggccgcgg ttcaccatct cctggtagcc gtcctcgtag tacagctgcg ggtcgcgctc
    19681 gtaggtggcc ttcagcgcgt cggccaggtc ggcggcggcg tcgccctcga tgagggtcac
    19741 gccgatgtac tcgccggtgg cgtcggccgg gtccatcagc ttggtgatgc ggcgcacgcc
    19801 cctggcgggc tcggtgacga ccttcatctc ctcgtcggcc agcttcttga ccgtgtcgag
    19861 ggcgaggatg atccgctgcc ccttgccgcg ggcgtcgagc agcgtctgct cgacggagac
    19921 ggggtggacg gtgtcgccgt tggccaggat cacgccctcc ttgatgacgt cccgggcgca
    19981 ccacagggag taggcgttgt tccactcctc ggccttgtcg ttgtccacca ggtggagctt
    20041 gacgccgtac ttcttctcca gggcggccct gcgctcgtgg acggcctcct tgcggtagcc
    20101 cacgaccacg gcggcctcgg tgaggccgac ctcgcggaag ttgccgaggg tgaggtccag
    20161 cacggtggtg gtgccctcgc ccgccgggtc caccggcacc agggccttgg ggagggtgtc
    20221 ggtgtagggg cgcagacgcc gtccggcgcc ggcggccagc acgaggccga tcatgcgggt
    20281 tctcctgttt cgtcgtgtac ggcgggtgcg tgtgaggaca cccagaaacg gacgctctcg
    20341 gtgagcaccg tgagcgccag ggccccggcc agggccgtga gcgcgatcgt gaagccctgc
    20401 ccggcggccc agagggcggc ggcggccgtg accgccacaa cgcgtccctc gtgcccgccg
    20461 atcgccagca ccagccggtg cggcggggcg ccggtgccgc cgcggatgcg gtacaccgtg
    20521 tcgtagtgat ggtaggcgac cgccgcgacc agcccgaacg ctgcgggcag ggcccccgcc
    20581 gcgtccgacc gggcggcgag taccaggacc gtggtgtact ccgccgcgcg gaagaggggc
    20641 ggcaccagcc agtccagcgc gcccgccggc gggcgggcga cggccagccc ggacaggacg
    20701 gcgtagccga gcgcggcggc cggcagccag gggccgaccg gggcccacag cgcggcggcc
    20761 accagggcgg ccgagccgag cagggccggg gccggggcgg tgaacgcgga cggccgccca
    20821 ccgcgcaccc cgcgcgtcct ggacgcggcg gcccgggcca cgccctcggc cagcggcccg
    20881 gagtcggcca gctcggccag ggcccgcacg gcgcggtcgg tgcgcacgcc cttgcgggtc
    20941 agggagcgca gcacccgccc ggcggtggtg tagcaggcgg cgaacgcgca gccgatcagc
    21001 agcacggtga aggtggtgcg gggggtggtg agggcggtga ggacggcgat cagcgcccag
    21061 cgctcgccga tcggcagcac gatcatgcgg cgggcccaca ccgtccagcc gacccggtcg
    21121 agtctccccg acagggcggc ggcggggtcg gcgctcccgg ccgcgggctc cccctcgcgc
    21181 tcccggccgc cgtccctcct gtagtggtcg gcctcgttga aggagaagtc caccacgtgg
    21241 cggcaggtct ggagcaccat cgcgcccagc gccagggccc acacgtcgtc gccgccgcgg
    21301 gccgcgccga gggccaggcc cgcgtagtag gcgtactcct tggcccggtc gaaggtggcg
    21361 tccagccagg ctccgagcgt ggagtacctc agcgcgtagc gggcgagctg gccgtcggcg
    21421 cagtccagca cgaacgaggc gatcagcagc accccggccg cgacgaagcc gccgcgggtg
    21481 ccggtggccg cgcaggcggc ggcgatcagc gcggtgagca gcgaggcggt ggtcacctgg
    21541 ttgggggtca gcccgcgccg ggcgcaccag cgggcgaggt ggcgggagta ggggctgacg
    21601 aggaaggtgg tgaagaagcc gtcgcgggac ttcaccgccg agcgcagccg cacccgctcc
    21661 tcgtcgacgg ccgccacggc ccgctcggcc tcggcgcgct ccgcgccgtc ggcgggtacg
    21721 gcggcgacga ggacgcccag ctcgggccgg tgcacggccg ggccccggcc gtcctcctcc
    21781 agtgcggcgg ccgcccggtc gggcaggacg gcgggctcgg gggcggcggt gcgcgccacg
    21841 cctcccgacg cggacggcgc ggtccgcgcg gacggtgccg cggcggcgga cacggcggac
    21901 acggcgcggg ccagggcggc gcgcgcggtg ggctggacgg ccagcgcgcc ggggatcgcg
    21961 gcggcgggga aacgcgggtc ggtcagggcc agccgcaggc tgtgcgtgtg cccgacgaag
    22021 cgagggtcga cgagggcgac gcgctcaccg gccgggacgg ccgccagcgc cgcctccacc
    22081 ccggcggtgt cctccgccac ccgcacgtcg aaacccagcg accgcagacc gccctccagg
    22141 ggcgcccccg cgaccggcgg accggtgaga atggcggtcg acaagaacga actcactcct
    22201 tgaaagccgt actgtccgcg acgcggtccg tgagcgagcg gcatccgggc agcggtcaca
    22261 gtgcgccatc acccgttcgg ggcaggcagc acgtggccag aggttatcgg ataggtggaa
    22321 gcgtccgttc accccgcatt caccgggggg aagcgcccca ccgtcacgaa aggtgacaga
    22381 acaccacgga ccgcgttcca gggtcctcga tcccggcggc tcgcacaagg agcgtgtccg
    22441 cgacggtccg cgaccggtgg ttaggctgcg gccatgacgt ggctggtgac cggaggagtc
    22501 ggatacgtcg gcgcacatgt ggcgcgggcg atggcggagg ccggcgagga ggtcgtcgta
    22561 ctcgacgacc tctccagcgg cctgcccgag cggctgccgc ccggggtgcc cctggtgcgc
    22621 ggctcggtcg ccgaccgcgg gctgctcgac cgcacgatcg ccgggcacgg ggtcacgggc
    22681 gtggtgcatc tggcggcgaa gaagcaggtg ggcgagtcgg tggagcatcc gctgacgtac
    22741 taccgggaga acctgtacgg gctcacggtg ctgctggagg ccgtggtggc cgccggggtg
    22801 cggcgcttcg tgttctcctc ctccgccgcc gtctacggca tgcccgacgt ggacacggtc
    22861 accgaggaca ccccctgcgt cccgatgaac ccctacggcg agacaaagct ggcgggcgag
    22921 tggctggtgc gcgccgccgg gcgggcgcac gggctgtcca ccgcctgcct gcgctacttc
    22981 aacgtggcgg gggccgcgcg gccggagctg tcggacgtcg gcgtgtccaa cgtcatcccg
    23041 atgttcttcg acgccctcac ccgcggtgag gccccgcgga tcttcggcga cgactacccc
    23101 acccccgacg gcacctgcgt gcgcgactac atccacgtcg ccgacctggc cgaggcgcat
    23161 ctggccgcag cccgccggct ggccgggctc ccggccggcg aggacctgac ggtcaacgtg
    23221 ggcaccggcg agggcgtgtc ggtgcgggag ctggccggtc tcgtcgccga gaccaccggc
    23281 atccgcgagc ccgccccggt ggtcgccccg cgccgccccg gggaccccgc gcgggtggtg
    23341 gcctcggccg ggcggatcgg cgtggagctg ggctgggcgc cccggtacgg ggtacgcgag
    23401 atggtggcct cggcctgggc gggctggcgc ccgcgcggcg ccgacggcct ccagcgggaa
    23461 ggggccgcgt tccccgagtg atccgggccg gtcctccgaa cgggcggacg ccatccgcca
    23521 ggtgaatgga aagcgcaggt cagaggggat gacaacggtg ttcagtgccg cgttgcccca
    23581 taccccccac ccgtagttca ctgggatcgt ccgcaccggt cgcaggcggc accggccgcc
    23641 atacgggagg catcatccat gggcgcaggg cacaaccacg gcgggccgcg gccggccggg
    23701 ccgggtacgg cgggagccgc gtaccggggg cggctgcgcg cggccctggc catcgcggtc
    23761 gtcctgctgc tcgccgagct cgcgggcgcc gcgctgaccg gttcgctggc gctgctggcg
    23821 gacgccggcc atgtggccac cgacgcggtc ggcatcggga tggcgctgct ggcgatccac
    23881 gtcgccaacc ggcccggcag cgagcggcgc accttcggtc tcgcccgcgc cgagatcctc
    23941 gccgcgctgc tcaacgccct gctgctgctc ggggtgggcg gctacatcct ggtggaggcc
    24001 gtcgagcggc tgcgccaccc cgaggaggtg cccggggggc tgacggtcct gttcggcgtc
    24061 gtcggcctgg ccctcaacgg cctgtccctg gccctgctga tgcgcgggca gcgcgagagc
    24121 ctgaacgtgc ggggcgcctt cctggaggtg gcggcggacg ccctgggttc ggtggcggtg
    24181 atcgccgccg cgctggtgat catgctcacc ggctggcggc aggccgaccc cgtcgcctcg
    24241 ctgctgatcg cggtgctgat cgtgccgcgg acggtacggc tggcgcgcga ggcgatcgac
    24301 gtcctgctgg aggccgcgcc ccggcatgtg gacatggccg gggtgcgggc gcacatcctg
    24361 ggcgtgcccg gggtggagga gctgcacgac ctgcacgtgt ggaccatcac ctccgggatg
    24421 ccggtgctct ccgcgc
//
