LOCUS       NZ_FOKG01000016        22027 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Amycolatopsis marina strain CGMCC 4.3568, whole genome shotgun
            sequence.
ACCESSION   NZ_FOKG01000016
VERSION     NZ_FOKG01000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Amycolatopsis marina
  ORGANISM  Amycolatopsis marina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900111885.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:41:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,708
            CDSs (total)                      :: 6,643
            Genes (coding)                    :: 6,572
            CDSs (with protein)               :: 6,572
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 22 of 71
            Pseudo Genes (incomplete)         :: 62 of 71
            Pseudo Genes (internal stop)      :: 4 of 71
            Pseudo Genes (multiple problems)  :: 15 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:06:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 54898
            Orig. end                         :: 76925
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOKG01000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22027
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22027
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22027
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12027](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12027
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(300..2282)
                     /locus_tag="BM199_RS23805"
                     /old_locus_tag="SAMN05216266_11654"
     CDS             complement(300..2282)
                     /EC_number="3.4.-.-"
                     /NRPS_PKS="Domain: Abhydrolase_1 (436-553). E-value:
                     8.3e-11. Score: 33.9. Matches aSDomain:
                     nrpspksdomains_BM199_RS23805_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629723.1"
                     /locus_tag="BM199_RS23805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11654"
                     /product="S9 family peptidase"
                     /protein_id="WP_091675599.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-10, bitscore: 34.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 3e-47, bitscore:
                     153.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPADIELLTVPGSLTLRGDLLVAGLSRPDLADNSYRSSLRRIGL
                     GGGDLPWTRGTRDSAPVLSPDGRWIAFLRAGTGDGPAGSAQLHLMPTDGGEAVRLTSLP
                     LGAGAPVWDPASARIAFVARVPEPGRYGTRPADGAKDVAPAPADEAPRRITRLDYRIDD
                     IGFLLDRPARLFVLDVEEALRGVGAGEPVDPEPLTDGPADVCDPAWTPDGDAMLVSAAR
                     DWARTETVCSDLYRIPVAGGEPELVVRSEGTADHAVVAEDGTIWFYGTEFAGLDDIARN
                     TGLWAAALPEPGGQPSRPRRVTDAESVDCAPGAGVPVVRGEDVLVVVRHRGAAELRAVP
                     KRAERASLAALRLLAGERSCVRTFTADGERIAAVVATAESGGEVVLIEQGEQRVLTDFS
                     APVRKVGVRPLHELTATSTGDYPVHGWLVLPEGKGPHPVLLLVHGGPFAPYEWSLFDEA
                     QVYASAGYAVVLANPRGSAGYGQEHGRTVIGGLGTVDADDLLAMLDAALERPDLDSARV
                     GVMGGSYGGFMTGWLAAHHGHRFRAAWSERAVNAWDSFAGSSDIGWMFAQGYIGTDPEE
                     QRKRSPLSYAGQIGLPFAVVHSEQDWRCPLEQAQRMFVALRQNGVEAELILFPGEGHEL
                     TRTGSPRHRRQRFDAVLEWWSRHLG"
     aSDomain        complement(624..974)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM199_RS23805_Abhydrolase_1.1"
                     /evalue="8.30E-11"
                     /label="BM199_RS23805_Abhydrolase_1.1"
                     /locus_tag="BM199_RS23805"
                     /protein_end="553"
                     /protein_start="436"
                     /score="33.9"
                     /tool="antismash"
                     /translation="PVLLLVHGGPFAPYEWSLFDEAQVYASAGYAVVLANPRGSAGYGQ
                     EHGRTVIGGLGTVDADDLLAMLDAALERPDLDSARVGVMGGSYGGFMTGWLAAHHGHRF
                     RAAWSERAVNAWD"
     gene            complement(2313..3386)
                     /locus_tag="BM199_RS23810"
                     /old_locus_tag="SAMN05216266_11655"
     CDS             complement(2313..3386)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155108.1"
                     /locus_tag="BM199_RS23810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11655"
                     /product="TerC family protein"
                     /protein_id="WP_091675602.1"
                     /transl_table=11
                     /translation="MNVPLWVWLATVGGLLVLIAIDLVVVDRKPHQVTTGEAARWVTFY
                     VSCAVLFGIGVWILGGHDFGVEFFTGYITEYSLSVDNLFIFMVIMSSFKVPAIHQHRVL
                     LIGILLALVMRGAFIAVGAALIAQFVWVFFLFGAILVWTAVSMVREKGADEEYHENAVT
                     RWVRKIFPVTEDYIGHSMVVKRDGKRWITPMFVVIVAIGSADLLFAVDSIPAIFGITQE
                     AFLVFTANAFALMGLRQLYFLLGGLVTKLVYLSRGLAIILAFIGAKLFLHALHEYHVVP
                     EWMEINNWVSLGVIIAVLTLTTVFSLRKASRDPDAAGTDLQLNALSPEERAAAGQGGGA
                     EEEGHAEAGHNHPKSGS"
     misc_feature    3381..3394
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.67"
                     /tool="antismash"
     misc_feature    complement(3386..3395)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            3685..6558
                     /locus_tag="BM199_RS23815"
                     /old_locus_tag="SAMN05216266_11656"
     CDS             3685..6558
                     /NRPS_PKS="Domain: Abhydrolase_1 (74-180). E-value: 6e-14.
                     Score: 44.2. Matches aSDomain:
                     nrpspksdomains_BM199_RS23815_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465474.1"
                     /locus_tag="BM199_RS23815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11656"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_091675605.1"
                     /sec_met_domain="PF00561 (E-value: 2e-12, bitscore: 40.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFARLLPPGRRRHAALALAVAVLAAGALVWANTAEEPSPVATID
                     EFIEVPAAPGSTDRLQLDTTLYTPERTPAPAVLLPHGFGGDKTSVAREAGELAERGFVV
                     LAYSARGFGRSTGEIALNDPRFEVADASRLIDHLATLPEVVTDTEGDPRVGVTGASYGG
                     ALALLLAGTDDRIDAIAPVITYNDLAQGLIPNTASTEAPAAGTPAPGNFAPDGVFKQSW
                     AGILFSAGSGAPTPAGPAAEAIEPGAEPDDNELSGGQGAAGGANLPSGGRQPGDTPAAD
                     PCGRFTDEVCRAYTDVATDGSADARTTELLRRISPVSVTDRITAPTLLVQGENDTLFGL
                     DQADATARQITEAGGEVSVVWYTGGHDGGAPGPQLRGTIADWLDFRLTGEGSDPVPGFT
                     YEVQGALRTNGTPSVRSVEAQEYPGLSGGETDRRGVRLEGPEQTIVNPPGGNPAAVSGL
                     PGLNRIVSGSSRLSSLFTIDPPGQSAGFVSEPVQSQLLITGATTVRLRVAADGPVPESG
                     AVLFAKLYDVSPDGARVLPGNAIAPLRIPDLPEDGSPVEVTVTLPGVVRPIEEGHALQL
                     VVGTTDQSYTGPAAPAAYRVSLADDAIAVPVVPGVTAGGAWPVGQLLGIAGVLAAAIAV
                     AAIAALRRRRAHHVDATLADTPLVIENLTKSYPGGLTAVKDLSFRVERGQVLGLLGPNG
                     AGKTTTLRMLMGLISPTAGQIKVFGHTVTPGAPVLSRIGSFVEGSGFLPHLSGAANLRL
                     YWASTGRPVERAHLDEALEIAGLGDAVHRKVRTYSQGMRQRLAIAQAMLGLPELLVLDE
                     PTNGLDPPQIHQMREVLQRYAATGRTVLVSSHLLAEVEQTSTHVVVMHRGRLVAAGEVG
                     DIVAAGGEATFRVDQPEEAAAALRAVGGVSTVDIEGALVHADLDGLPRAEAVAALVRAG
                     IAVEQAGPRRRLEDAFLQLVGEGESSG"
     aSDomain        3907..4224
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM199_RS23815_Abhydrolase_1.1"
                     /evalue="6.00E-14"
                     /label="BM199_RS23815_Abhydrolase_1.1"
                     /locus_tag="BM199_RS23815"
                     /protein_end="180"
                     /protein_start="74"
                     /score="44.2"
                     /tool="antismash"
                     /translation="PAVLLPHGFGGDKTSVAREAGELAERGFVVLAYSARGFGRSTGEI
                     ALNDPRFEVADASRLIDHLATLPEVVTDTEGDPRVGVTGASYGGALALLLAGTDDRIDA
                     IA"
     gene            6551..7519
                     /locus_tag="BM199_RS23820"
                     /old_locus_tag="SAMN05216266_11657"
     CDS             6551..7519
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683527.1"
                     /locus_tag="BM199_RS23820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11657"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_091675607.1"
                     /transl_table=11
                     /translation="MGNSTRGSAAGANPGADHGVHTDPAALLELTDAAEHEPTEVAPDG
                     SVVGYRASRTLPLAVELGRQLRRRRTQLVFGFVALLPFILVVAFEIGDANPNRRSGGFI
                     DLATASAPNFVVLALFVSSTFLLPMIVALFFGDTIASEASWSSLKYLLAIPVPRHRVLR
                     QKAIASGLLSAGALALLPTVALLVGVIWYGAGDAISPTGDAVPFGDSIIAMILAVAYIV
                     VQLSWVAGLALLLSVSTDAPLGAVGGAVLVSIVSQILDQITALGDLRDFLPTHYSFAWM
                     DLISTDIDWTDIANGALLSVVYATVFLLLASRRFATKDITS"
     gene            complement(7541..8089)
                     /locus_tag="BM199_RS23825"
                     /old_locus_tag="SAMN05216266_11658"
     CDS             complement(7541..8089)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /locus_tag="BM199_RS23825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11658"
                     /product="GNAT family protein"
                     /protein_id="WP_091675806.1"
                     /transl_table=11
                     /translation="MNERLTAGGDLWLRPWAPDDLDAVLCAFTDPEMWRQSEEPVDTVP
                     AAAAWIAARQRHWATGTGYSWAVLDARSVVLGCVEVGAVNRRHGCGWVSYWTTKAARGR
                     GVATAACRTASDWALYDLGLHRLELGHRLNNPASCQVATRAGYRPEGVQRDKLRYDGRW
                     YDVEIHARLVTDRGFAAAS"
     gene            complement(8151..8723)
                     /locus_tag="BM199_RS23830"
                     /old_locus_tag="SAMN05216266_11659"
     CDS             complement(8151..8723)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223589.1"
                     /locus_tag="BM199_RS23830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11659"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_091675610.1"
                     /transl_table=11
                     /translation="MIEGRPVRADARRNRDRLLAEAEAVFRDRGTGASLEDIARGAGVG
                     IGTLYRHFPTREALLEALMQDRFSTLCSRSDELLDARSPRAALLSWLREFVASSSRYRG
                     LPASVMATLANEESRLSASCRAMGEAGQRLLVRAQQAAEVRSDLRIDELLPLAASISWA
                     AEHRQEDIDRFLVLLFEGIGCAPDPIA"
     gene            8826..9737
                     /locus_tag="BM199_RS23835"
                     /old_locus_tag="SAMN05216266_11660"
     CDS             8826..9737
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336531.1"
                     /locus_tag="BM199_RS23835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11660"
                     /product="TIGR03620 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_091675614.1"
                     /transl_table=11
                     /translation="MPDPQHRPGKIGIWTFAFDAHPAGRVRDAAAELEELGYRAIWFGE
                     ALGREAMTQAALLLGATHRAVVATGIANVHLRTPLTMAAAERSLAEQYRGRLLLGLGGH
                     RVPGSPNSFGGYRVPMSEKPVSDMRDYLDTMDTAPLAGATPATAPRRVLAALGPRMLDL
                     AAERTSGAHSYFVPVAHTAMARERMGTGAYLAVEQAVVLDSDPERVRQLQRAHVGAYLR
                     AQHQRNNLLRLGFDETELADGGSGRLNDALVAGGDIKAISARVRAHLDAGADHVCLQVL
                     TPSPGELPLREWRELAALVGEH"
     misc_feature    complement(9754..9765)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            9823..9921
                     /gene="pqqA"
                     /locus_tag="BM199_RS23840"
                     /old_locus_tag="SAMN05216266_11661"
     CDS             9823..9921
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019813815.1"
                     /locus_tag="BM199_RS23840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11661"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_091675617.1"
                     /transl_table=11
                     /translation="MIETGEREVWSTPDFVEYETPMEVTAYLGRME"
     misc_feature    9843..9858
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.73"
                     /tool="antismash"
     misc_feature    9956..9967
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.79"
                     /tool="antismash"
     gene            10001..10693
                     /gene="pqqC"
                     /locus_tag="BM199_RS23845"
                     /old_locus_tag="SAMN05216266_11662"
     CDS             10001..10693
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670612.1"
                     /locus_tag="BM199_RS23845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11662"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_091675619.1"
                     /sec_met_domain="TIGR02111 (E-value: 2.2e-85, bitscore:
                     278.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDSALSENEFVAALRGLEPRYWGAHPFHRRLHGGDLGKEELRAW
                     AANRWYYQRRLPQKDAAIISNCDVTAIRRRWLDRIVYHDGRTEGEGGAERWLRLCEAVG
                     LTRAEVLDERHVVPGVRFAVDAYVDFARTRPWQEAVASGLTEMFSGHLMRRRVSDMLAS
                     YPWISDSDLAYFTNRIGAVSGEGQEALDVVVRYCRTREQQDRAVAALSFKCDVLWSMLD
                     AIDLAAKG"
     gene            10697..10951
                     /gene="pqqD"
                     /locus_tag="BM199_RS23850"
                     /old_locus_tag="SAMN05216266_11663"
     CDS             10697..10951
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003079638.1"
                     /locus_tag="BM199_RS23850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11663"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_091675622.1"
                     /sec_met_domain="PqqD_RRE (E-value: 6.6e-25, bitscore:
                     79.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4e-13, bitscore: 42.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRPRLRRGVRLTYDKTRDTHVLLYPEGVLVPNPTAATVLGLCDG
                     NRTVQDIVAALGQRYSGVREHEVHGVLARLVERRMVEWT"
     aSDomain        10700..10942
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BM199_RS23850_PqqD_RRE.1"
                     /evalue="1.40E-25"
                     /identifier="RREFam006.1"
                     /label="BM199_RS23850"
                     /locus_tag="BM199_RS23850"
                     /protein_end="82"
                     /protein_start="1"
                     /score="79.8"
                     /tool="antismash"
                     /translation="DRPRLRRGVRLTYDKTRDTHVLLYPEGVLVPNPTAATVLGLCDGN
                     RTVQDIVAALGQRYSGVREHEVHGVLARLVERRMVE"
     gene            10942..12027
                     /gene="pqqE"
                     /locus_tag="BM199_RS23855"
                     /old_locus_tag="SAMN05216266_11664"
     CDS             10942..12027
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005150538.1"
                     /locus_tag="BM199_RS23855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11664"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_091675626.1"
                     /sec_met_domain="PF04055 (E-value: 5.3e-22, bitscore: 72.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.1e-13, bitscore:
                     42.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.7e-13, bitscore: 42.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVTNAVNAPLGMLAELTHRCPLHCPYCSNPLELTAREDELGTDE
                     WLSVLEQARELGVLQVHLSGGEPLSRADLPLLVSRAGELGCYVSLVTSGLGLTESRLAD
                     LVDRGLAHVQLSVQAADSARANLLAGARAHEHKITAAGLVTRAGLPLSVNVVLHRANHD
                     QLEAMIDLAERMGADRLELANTQYYGWALRNRAALQPTREQLAAAEPIVRAATERLRGR
                     MDLVYVLADYYESYPKPCMSGWGSRQLTVAPDGTVLPCPAATAISTLTLENVRNRTLAD
                     IWYQSESFNAYRGEDWMRDPCRSCDRRSIDFGGCRCQAFQLTGDAAATDPVCTLSPDRA
                     LVERILEAPREDADFVMRGPR"
     gene            12024..12911
                     /gene="pqqB"
                     /locus_tag="BM199_RS23860"
                     /old_locus_tag="SAMN05216266_11665"
     CDS             12024..12911
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631257.1"
                     /locus_tag="BM199_RS23860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11665"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_091675629.1"
                     /transl_table=11
                     /translation="MRAVLLGTAAGGGLPQWNCACANCRAARQGTIAPRAQDCLAISVD
                     GHGWYLLNASPDIRAQILSCPALAAGPGPRDTPVRGVLLTDGELDHTLGLIQLKEAAGL
                     RVWAPEAVLNTLPAREIVGRYAGWEWLSPSTGAPDIDGLRISTLPVSDKRPKYAAGSPA
                     EGPWVVAYRISDPVTGSALVYAPCLAGWPPGFDEFCAGASHVLLDGSFFAPDEMSTATD
                     TAVGSRAQLAMGHLPMSGTGGSLDRIRRAESGTRWLYTHINNTNPVLDPRSPEFAEMSA
                     AGAGLARDGTELRV"
     assembly_gap    13062..13126
                     /estimated_length=65
                     /gap_type="repeat between scaffolds"
     gene            complement(13230..15386)
                     /gene="uvrB"
                     /locus_tag="BM199_RS23865"
                     /old_locus_tag="SAMN05216266_11666"
     CDS             complement(13230..15386)
                     /EC_number="3.1.25.-"
                     /GO_component="GO:0009380 - excinuclease repair complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uvrB"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003070662.1"
                     /locus_tag="BM199_RS23865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11666"
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="WP_091675631.1"
                     /transl_table=11
                     /translation="MAFATEHPVLAHSEFRPVSDVPRSDGKFTVVSDYQPAGDQPKAID
                     ELERRIRAGEKDVVLLGATGTGKSATTAWLIERVQRPTLVMAPNKTLAAQLANELRDLF
                     PNNAVEYFVSYYDYYQPEAYIAQTDTYIEKDSSVNDDVERLRHSATMNLLSRRDVIVVA
                     SVSCIYGLGTPQSYLDRSSSLKVGEEVDRDTFLRALVDVQYTRNDLAFARGTFRVRGDT
                     VEIIPAYEELAIRVEFFGDEIDKLYYLHPLTGDIVNEVAEVRIFPATHYVAGPERMEKA
                     IKTIQSELEDRLATLEKQGKLLEAQRLRMRTNYDIEMMQQVGFCSGIENYSRHVDGRPE
                     GSAPATLIDYFPEDFLLVVDESHVTVPQIGGMYEGDMSRKRNLVEHGFRLPSAMDNRPL
                     TWEEFSDRIGQTVYLSATPGPYEMGQTGGEFVEQVIRPTGLIDPEVVVKPTEGQIDDLV
                     HEIRTRADKDERVLVTTLTKKMAEDLTDYLLELGIRVRYLHSEVDTLRRVELLRQLRSG
                     DFDVLIGINLLREGLDLPEVSLVSILDADKEGFLRSGTSLIQTIGRAARNVSGQVHMYA
                     DRITDSMQHAIDETNRRRAKQIAYNTERGLDPQPLRKKIADILDRVYDEAEDSEDVAIG
                     GSGRNSSRGKKPEQGGGVRSSGMLADKDVGAMPRAELADLIQQMTEQMMQAARDLQFEL
                     AARLRDEVADLKKELRGMDAAGIK"
     gene            15469..15984
                     /locus_tag="BM199_RS23870"
                     /old_locus_tag="SAMN05216266_11667"
     CDS             15469..15984
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335472.1"
                     /locus_tag="BM199_RS23870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11667"
                     /product="DUF402 domain-containing protein"
                     /protein_id="WP_091675633.1"
                     /transl_table=11
                     /translation="MPDLHPPKTEIFDVPGMSNTDPKGIVRDVERFQVESFGLYMARPT
                     PGRRQFHYLESWLLPGLGLRITDFWFTEGHEHDQDFYLDVVDIERHDDRWRATDLYLDI
                     VLRDARGLDVLDSDELLAATSADLLPAYTARQALDTTFTTVDGLARHGYRLQEWLRTMD
                     ITLTWQRH"
     gene            complement(16037..17233)
                     /gene="coaE"
                     /locus_tag="BM199_RS23875"
                     /old_locus_tag="SAMN05216266_11668"
     CDS             complement(16037..17233)
                     /EC_number="2.7.1.24"
                     /GO_function="GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159313.1"
                     /locus_tag="BM199_RS23875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11668"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_091675634.1"
                     /transl_table=11
                     /translation="MLRVGLTGGIGAGKSTVATRLVEHGAVLIDADLLAREVVEPGTEG
                     LAEIVEAFGPDVLTRDGALDRAALAARAFADEQSRRRLNGIVHPRVGARTAELMRNAAP
                     DAIVVHDIPLLVEGGLAPHYHLVVVVDADEEVRVRRLVEARGMSEADARARIAAQASVE
                     QRRAAADVWLDNGGARDIVLAEVDALWADRLVPFEANLRLRKPRPPRSPLVSPYDETWP
                     GQAERVLGRVRAAAGDRAARADHIGSTAVPGLPAKDVLDLQLTVPTLDVADELADALSD
                     AGFPRAEGHWFDDPQDGTAGSAVWDKRFHFGADPVRPVNLHVRAEEGPAWRLALLFRDW
                     LRANPPELAAYAEVKRRLAGAHAGDGTTQPYAEEKQDWVNDAFTRAEEWAERTGWSPA"
     gene            17421..17633
                     /locus_tag="BM199_RS23880"
                     /old_locus_tag="SAMN05216266_11669"
     CDS             17421..17633
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017981917.1"
                     /locus_tag="BM199_RS23880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11669"
                     /product="hypothetical protein"
                     /protein_id="WP_091675638.1"
                     /transl_table=11
                     /translation="MPDSRHTGKHRLGTPGLVHCVMHRPVAEALTEYRRTWLTALLVPA
                     KHSLAGLRRRARAAAHEHAWAPATT"
     gene            complement(17926..19443)
                     /gene="rpsA"
                     /locus_tag="BM199_RS23885"
                     /old_locus_tag="SAMN05216266_11670"
     CDS             complement(17926..19443)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159322.1"
                     /locus_tag="BM199_RS23885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11670"
                     /product="30S ribosomal protein S1"
                     /protein_id="WP_091675640.1"
                     /transl_table=11
                     /translation="MTTDTTTAPTATAPAQQVAINDIGTEEDFLAAIDKTIKYFNDGDI
                     VEGTIVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPAEVVTVGDEVEALVLQKEDKE
                     GRLILSKKRAQYERAWGTIEELKEKDEPVSGTVIEVVKGGLILDIGLRGFLPASLVEMR
                     RVRDLQPYVGRELEAKIIELDKNRNNVVLSRRAYLEQTQSEVRSEFLNALAKGQVRKGV
                     VSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPSEVVEVGQEVTVEVLDVDMDRERVSL
                     SLKATQEDPWRQFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGLVHISELAERHVEI
                     PEQVVQVNGDVMVKVIDIDLERRRISLSLKQANEGLTTDAEFDPTQYGMAADYDEQGNY
                     IYPEGFDPDTQEWQEGYDTQREEWERQYAEAHARYEQHMKQIAKAAEADAEAAAQAIAG
                     GGESSSGGGGEQSYSSTPSDSAPKSTGGTLASDEQLAALREKLSGGA"
     misc_feature    19522..19533
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.53"
                     /tool="antismash"
     gene            19829..20635
                     /locus_tag="BM199_RS23890"
                     /old_locus_tag="SAMN05216266_11671"
     CDS             19829..20635
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007023426.1"
                     /locus_tag="BM199_RS23890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11671"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_245788625.1"
                     /transl_table=11
                     /translation="MHTAGVAYRPVDSAEAASANLAWWDADADDYHATHGEFLGESDFR
                     WCPEGLLEADARLLGEVRDTDVLEVGCGSAPCTRWLHTQGARAVGVDLSGGMLRHGLAA
                     GERTGIRVPLVQANAERLPLAGDSFDTACSAFGAVPFVASVETLFAEVARVLRPGGRWV
                     FAVTHPMRWIFPDDPGPTGLTATQPYFDRTPYVEVDADGRATYVEYHRTMGDYVRALAA
                     AGFRLTDLIEPEWPEGHTRTWGQWSPLRGKLFPGTAIFHTVKERQT"
     gene            20632..21549
                     /locus_tag="BM199_RS23895"
                     /old_locus_tag="SAMN05216266_11672"
     CDS             20632..21549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660417.1"
                     /locus_tag="BM199_RS23895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_11672"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_091675646.1"
                     /transl_table=11
                     /translation="MTDRTAEQSEHFARIDPLLPPVTDLPEGEHLTAVLPDGREVHGVL
                     YRAVYGAGSPESLWAARENWELTPLIGNTGAEGMSALLGALRRRLDREPPTQDSACAVA
                     WPSRDAEATRALLDHGLQPLNALAVRPNRPAPEVDVPGVLVRRARPVDEEEIIALRMNE
                     LRYSALVGPNVVRENATELITAEVRRGLVFGGRTWIAESGGAAVGLASCGWTTPAAGSS
                     IAGRLGWGRWGYVGTLSVIAPARGGGVGQALMSVAHDQLNLDDVEGTFLFYSPTNPLSP
                     VFWHRQGYRPLWTMWEIRPASALR"
ORIGIN
        1 gcgcggcgtt cagcgatctc gacggcgtct ggtatcggtc ctcaatggac ggaggtggcc
       61 cggcgatctg cctgtgggat ccgcccgccg gttccgccct gccggacaat ccggatgtcc
      121 tgctcccact ggaccacccc ggcctcgacg tgccactggg ccgagtctgc gaagaactca
      181 actacgtcat ggtcaactga ccggccgtca cctggagcgc ctgcaagtac ccccaagcaa
      241 gatcagctac gtcgtcaact gccgccaagc ggcgcgccgc cagccactgc cgacccccgt
      301 cagcccaggt gccgtgacca ccactcgagc accgcgtcga atcgctgtcg ccgatgccgg
      361 gggctgccgg tcctggtcag ctcgtgcccc tcaccgggga acaggatcag ctcggcctcg
      421 acaccgttct ggcgcagcgc gacgaacatc cgctgcgcct gctccagtgg gcaccgccag
      481 tcctgctcgg agtgcacgac cgcgaacggc aggccgatct ggccggcata gctcagcggg
      541 ctgcgtttgc gctgctcctc aggatcggtg ccgatgtacc cctgcgcgaa catccagccg
      601 atgtcggagc tacccgcgaa ggagtcccag gcgttgaccg cccgttcgct ccacgccgca
      661 cggaagcggt gaccgtggtg cgccgcgagc cagccggtca tgaagccgcc gtaggagccg
      721 cccatcacgc cgacgcgtgc agaatccagg tcgggacgtt cgagcgcggc gtcgagcatt
      781 gccagcaggt cgtcggcgtc gacggtgccg agcccgccga tcaccgtgcg tccgtgctcc
      841 tgcccgtatc cggccgagcc ccgcggattc gccagcacca ccgcgtatcc ggccgaggcg
      901 tacacctgcg cctcgtcgaa caggctccac tcgtacggcg cgaacggacc gccgtgcacg
      961 agcagcagga ccgggtgcgg gcctttccct tcgggcagca ccagccagcc gtgcaccgga
     1021 tagtcgccgg tggaggtggc ggtcagttcg tgcagcggcc ggacgccgac cttgcggacg
     1081 ggagcggaga agtcggtgag cacccgctgc tcgccctgct cgatcagcac gacctcgccg
     1141 cctgactccg cggtggcgac gacagcggcg atccgctctc cgtcggcggt gaacgtgcgc
     1201 acacacgaac gctcgcctgc cagcagccgc agggccgcca gcgacgcccg ctccgcccgt
     1261 ttcggcactg cccgcaactc ggccgcaccg cgatggcgga ccaccacgag cacgtcctcg
     1321 ccacgcacga caggaacacc cgctccgggc gcgcagtcca ccgactccgc atcggtcacc
     1381 ctgcgcgggc gcgacggctg cccgcccggt tccggcaggg cggcggccca tagaccggtg
     1441 ttgcgcgcga tgtcgtcgag gccggcgaac tcggtgccgt agaaccagat cgtgccgtcc
     1501 tcggccacca cggcatggtc cgcggtgcct tcgctgcgca ccacgagctc gggttcgccg
     1561 cccgccaccg ggatgcggta gaggtccgag cacacggtct cggtccgcgc ccagtcccgc
     1621 gcggcgctga ccagcatcgc gtcaccatcc ggtgtccaag cagggtcgca gacgtcggcg
     1681 ggaccatcgg tcaacggctc cgggtcgacg ggctcgcccg cgcccacacc acgcagcgcc
     1741 tcctcgacgt ccagcacgaa cagccgcgcg ggacggtcga gcaggaaacc gatgtcgtcg
     1801 atccggtagt cgagccgggt gatccggcgc ggggcctcgt cggcgggggc gggtgccacg
     1861 tccttggcgc cgtccgcggg ccgtgtgccg taccggccgg gctcggggac ccgtgcgacg
     1921 aacgcgatcc gagccgaggc cgggtcccag accggagcac ccgcgccgag cggcagcgag
     1981 gtcagccgaa cggcctcccc gccgtcggtg ggcatgaggt gcagttgcgc gcttcccgcg
     2041 ggcccgtcac cggtgcctgc ccgcagaaac gcgatccagc gcccgtcggg tgagagcacg
     2101 ggtgcgctgt cgcgcgtgcc acgggtccac ggcagatcgc cgccgcccag cccgatacgg
     2161 cgcagcgaac tccggtacga gttgtccgcc agatcgggcc gggacagtcc ggcgacgagc
     2221 aggtcaccac gcagcgtgag tgaaccggga acggtcagca gttcgatgtc ggcaggacgc
     2281 acagtcctga ccgtacatga ttgttagccg aactaactac cagatttggg gtggttgtgg
     2341 cccgcctcgg cgtggccctc ctcctcggcc ccgcccccct ggccggcggc cgcccgctcc
     2401 tccggcgaga gtgcgttcag ctggagatcg gtccccgcag catccgggtc cctgctcgcc
     2461 ttgcgcaggc tgaacaccgt ggtcagtgtc aggaccgcga tgatcacgcc gagcgagacc
     2521 cagttgttga tctccatcca ctccgggacg acgtggtact cgtgcagcgc gtgcaggaac
     2581 agcttggcgc cgatgaaggc gaggatgatc gccagccccc gggagaggta gaccagcttc
     2641 gtcacgaggc caccgagcag gaagtagagc tgccgcaggc ccatcagcgc gaacgcgttc
     2701 gccgtgaaga cgaggaacgc ctcctgggtg atcccgaaga tcgccggaat ggagtcgacg
     2761 gcgaagagca ggtcggcgct gccgatcgcc acgatcacca cgaacatcgg cgtgatccag
     2821 cgcttgccgt cgcgcttcac caccatgctg tggccgatgt agtcctcggt caccgggaag
     2881 atcttgcgca cccagcgggt caccgcgttc tcgtggtact cctcgtccgc gcccttctcc
     2941 cgcaccatgc tgaccgcggt ccagacgagg atcgcgccga agaggaagaa gacccagacg
     3001 aactgggcga tgagcgccgc gccgacggcg atgaaggcac cgcgcatcac cagtgcgagc
     3061 agaatgccga tcagcaggac ccggtgctgg tggatggccg ggaccttgaa cgaggacatg
     3121 atcaccatga agatgaacag gttgtccacg ctgagggagt actcggtgat gtagccggtg
     3181 aagaactcca caccgaagtc gtgaccaccg aggatccaga cgccgattcc gaacagcacg
     3241 gcacagctga catagaaggt cacccacctc gcggcttcgc cggtggtgac ctgatggggt
     3301 ttgcggtcga cgacgaccag atcgatcgcg atcaggacga gaagtccgcc gacagtcgcg
     3361 agccagaccc acaaggggac attcatcaaa aaacaaccct ccggttagcg gatagcagcc
     3421 actacccgga ggtctcttcc accggcgaac tcaccggccg gcggtgccgg gcgctcgccg
     3481 taccaccggt acaggggctc cgtgctgacg acaccgccgc gaaggaatac tcccctccac
     3541 gtcgctccgt atcttgcgcg tccgagatca acgacgccag tcaaggttgc gctggtcacc
     3601 tgaatcccta gcgttagctc cgtcacaccc tcgttggagg tacccacagc actctctcag
     3661 gaaacgacga atacggtcgt cgtcgtgccc tttgcccgac ttcttccccc cggccgtcgc
     3721 cgccacgccg ccctcgccct cgccgttgcc gtgctcgcgg cgggcgcgct ggtctgggcg
     3781 aacacggcgg aagagccgtc gcccgtggcg accatcgacg agttcatcga ggtccccgcc
     3841 gcaccaggat ccaccgaccg gctccagctc gacacgacgc tgtacacccc cgagcggacg
     3901 cctgcccccg ccgtcctcct gccccacgga ttcggcggtg acaagaccag cgtcgccaga
     3961 gaagcgggcg aactcgccga gcgcggcttc gtcgtcctcg cgtactccgc ccgcggtttc
     4021 gggcgcagca ccggcgagat cgcactgaac gatccccgct tcgaggtcgc cgacgccagc
     4081 aggctgatcg accatctcgc caccctcccc gaggtggtca ccgacaccga gggagacccg
     4141 agggtcggcg tcacgggtgc gtcctacggc ggagcgctgg cgttgctgct cgccggcacc
     4201 gacgaccgca tcgacgccat cgcgccggtg atcacctaca acgacctggc gcaggggctc
     4261 atcccgaaca cggcaagcac cgaagcaccc gcggcgggca ctcccgcacc gggcaacttc
     4321 gcgccggacg gggtgttcaa gcagtcctgg gcaggcatcc tcttctccgc gggttcgggc
     4381 gcgccgacac cggcaggccc cgccgccgag gccatcgagc cgggcgccga accggacgac
     4441 aacgaactct ccggcgggca gggggcggcg ggcggcgcga acctcccttc tggcggccgg
     4501 cagccaggag acacccctgc cgccgacccg tgcgggcgct tcaccgacga ggtgtgccgg
     4561 gcctacaccg acgtcgcgac cgacggcagc gcggatgcgc ggaccaccga gttgctccgg
     4621 cgcatctctc ccgtctcggt caccgaccgg atcaccgccc cgaccctgtt ggtgcagggc
     4681 gagaacgaca ccctgttcgg actcgaccag gccgacgcca ccgcacggca gatcaccgaa
     4741 gccggtggcg aggtcagcgt ggtctggtac acgggagggc acgacggcgg cgcgccgggc
     4801 ccgcagttgc gcggcacgat cgccgactgg ctggacttcc gcctcaccgg cgagggcagc
     4861 gatcccgttc cggggttcac ctacgaggtg cagggtgcgc tgcggaccaa cggcaccccc
     4921 tcggtgcgca gcgtcgaggc acaggagtat ccgggccttt ccggtggcga gaccgaccgg
     4981 cgcggcgtgc ggctggaggg tccggaacag acgatcgtga acccgcccgg cggaaatccg
     5041 gccgcggtga gcggactgcc cggcctcaac cgcatcgtca gcggctcttc acggctgtcg
     5101 agcctgttca ccatcgatcc gcccggtcag tccgcggggt tcgtctcgga gccggtgcag
     5161 tcgcagctgc tgatcaccgg tgccaccacc gtgcgactcc gggtcgccgc cgacggaccc
     5221 gtgccggaat ccggagccgt cctcttcgcc aagctctatg acgtctcacc cgacggcgcc
     5281 cgggtgctgc cgggcaacgc gatcgccccg ctgcgcatcc ccgacctccc cgaggacgga
     5341 tcgccggtgg aggtcacggt cacgctgccc ggcgtcgtcc ggcccatcga ggaggggcac
     5401 gcgctgcagc tggtcgtcgg tacgaccgat cagtcgtaca ccggccccgc cgccccagcc
     5461 gcgtaccgtg tctccctcgc cgatgacgcc atcgcggtgc cggtggtccc cggcgtcacg
     5521 gcaggcggcg cctggccggt cgggcagttg ctcgggatcg ccggcgtgct ggccgcggcg
     5581 atcgcggtgg ccgcgatcgc cgcgctgcgc cgcaggcgcg cacatcacgt cgacgccaca
     5641 ctggccgaca caccactggt catcgagaac ctgaccaagt cctatcccgg tggtctcacc
     5701 gcggtgaagg acctgtcgtt ccgggtggag cggggccagg tgctgggtct gctgggcccg
     5761 aacggcgcgg gcaagaccac cacgctgcgg atgctgatgg gcctgatcag tcccacagcg
     5821 ggccagatca aggtcttcgg gcacaccgtc acccccggcg cccccgtgct ttcccggatc
     5881 gggtcgttcg tggagggctc gggtttcctg ccccacctgt ccggcgccgc gaacctgcgg
     5941 ttgtactggg ccagcacggg aaggcccgtg gagcgggcac acctcgacga ggcattggag
     6001 atcgccggac tcggagacgc ggtgcaccgc aaggtgcgga cctacagcca gggcatgcgc
     6061 cagcggctgg cgatcgcgca ggccatgctc ggtctgccgg agctgctggt gctcgacgaa
     6121 ccgaccaacg gcctcgaccc gccgcagatc caccagatgc gcgaggtgct gcagcgctac
     6181 gccgcgaccg gacgcacggt gctggtctcc agccacctgc tcgcggaggt ggaacagacc
     6241 tcgacgcacg tggtcgtcat gcaccgcggc aggctggtgg cggcgggcga ggtcggcgac
     6301 atcgtcgcgg caggcgggga ggccaccttc cgggtggacc agcccgagga ggccgccgcc
     6361 gcactgcgag cggtgggcgg tgtgtccaca gtagacatcg aaggtgctct tgtgcacgcc
     6421 gacctcgacg ggctcccccg cgccgaggcc gtggccgccc tggtgcgggc cggaatcgcg
     6481 gtggagcagg ccgggccgcg gcgacggctg gaagacgcat tcctgcaact ggtcggagag
     6541 ggtgaatcca gtgggtaact ccacgagagg ttcggcagcg ggggcgaacc ccggagccga
     6601 ccacggcgtg cacaccgatc cggcggcact gctcgaactc accgacgcgg cggagcacga
     6661 gccgacggag gtggctccgg acggttcggt ggtgggctat cgcgcgtccc gcaccctgcc
     6721 cctcgccgtc gaactgggca ggcagttgcg caggcggcgg acccagctcg tgttcggttt
     6781 cgtggcgctg ctgccgttca tcctggtggt ggcgttcgag atcggtgacg cgaatccgaa
     6841 ccggcggtcc ggtggattca tcgacctggc cacggcaagc gcacccaact tcgtcgtgct
     6901 cgccctgttc gtgtccagca ccttcctgct gccgatgatc gtggcgctgt tcttcggtga
     6961 cacgatcgcc agcgaggcat cgtggtcgag cctgaagtac ctgctcgcca tacccgtgcc
     7021 gagacacagg gtgctacggc agaaggcgat cgcctcgggg ttgctgtcgg cgggagcgct
     7081 cgcgctgttg cccacggtcg ccctgctggt cggggtgatc tggtacggcg caggggacgc
     7141 gatcagtccc accggcgacg cggtgccgtt cggcgacagc atcatcgcga tgatcctcgc
     7201 cgtggcttac atcgtcgtcc agctctcctg ggtcgccggt ctcgcactgc tgctcagcgt
     7261 ctccacggac gcgccgctgg gcgcggtcgg cggggcggtg ctggtctcga tcgtctcgca
     7321 gatcctggac cagatcaccg cgctcggcga cctgcgggac ttcctcccga cgcactactc
     7381 gttcgcctgg atggacctga tctccaccga catcgactgg acggacatcg ccaacggtgc
     7441 actgctgtcc gtcgtgtacg ccacggtctt cctgctgctg gctagcaggc ggttcgcgac
     7501 gaaggacatc accagctgag ggtctttctg aggagtcggg tcagctcgcg gcggcgaaac
     7561 cccggtccgt gaccagccgg gcgtggatct ccacgtcgta ccacctgccg tcgtagcgga
     7621 gcttgtcgcg ctgcacgccc tccggccggt aaccggcacg ggtggcgacc tgacaggagg
     7681 ccgggttgtt caaccggtgg cccagttcca gtcggtgcag gccgaggtcg tacagggccc
     7741 agtcactggc ggtgcggcag gcggctgtcg cgactcccct gcccctggcg gccttggtcg
     7801 tccagtagga cacccagccg cagccgtgcc gacggttcac cgcgcccacc tcgacacagc
     7861 cgagcaccac tgaccgcgcg tccagcacgg cccacgagta gcccgtcccg gtggcccagt
     7921 gccgctgccg ggcggctatc caggccgcgg ctgcggggac ggtgtccacc ggctcctcgg
     7981 actgacgcca catctccggg tcggtgaagg cgcacagcac cgcgtcgaga tcatcgggag
     8041 cccacgggcg cagccacaga tcgccgccgg ccgtcagacg ttcgttcacc gatccagctt
     8101 cggtcagcac cgccgccggg tccaccggtt ttccggggtc cggcgcccgg tcacgcgatc
     8161 gggtccgggg cgcacccgat gccctcgaac agcagcacca gaaaccggtc gatgtcctcc
     8221 tgccggtgct ccgcggccca ggagatcgag gcggcgagcg gcagaagctc gtcgatgcgg
     8281 aggtccgaac gcacctccgc cgcctgctgg gcccggacca acagccgctg ccccgcctcg
     8341 cccatcgccc ggcacgacgc ggacaacctg gactcctcgt tggccagtgt cgccatgacc
     8401 gaggcgggca gtccacggta tctgctcgac gaggccacga actcgcgcaa ccaggaaagc
     8461 agggcggctc gcggggaacg cgcgtccagc agttcgtcac ttctcgaaca gagcgtcgag
     8521 aaccggtcct gcatcaacgc ttccagcagt gcttcacggg tcgggaaatg ccggtaaagc
     8581 gtgccgatgc cgacccctgc cccgcgcgcg atgtcttcca gggatgcgcc ggtaccgcgg
     8641 tcccggaaca ccgcttccgc ctcggcgagc agccgatcgc ggtttcggcg cgcgtcggcg
     8701 cgcaccggac gtccctcgat cacgtcagtc agctcctcac tgctcgacca cgcttgcaca
     8761 aacggaggca gcctccgtat tgtcgaaaac ggaggcaccc tcactttacc tggagagcag
     8821 acaccatgcc cgacccgcag caccgtcccg gcaagatcgg gatctggaca ttcgccttcg
     8881 acgcccaccc cgccgggcgg gtgcgtgatg ccgccgccga actggaggaa ctgggctacc
     8941 gcgcgatctg gttcggcgag gcgctcggca gggaagcgat gacacaagcc gccctgctgc
     9001 tcggcgcgac acatcgagcc gtagtggcga ccggaatcgc caacgtccac ctgcgcactc
     9061 ccctgaccat ggcggcagcg gaacgatcac tcgccgagca gtaccgcggc cggctgctgc
     9121 tcggcctcgg tggacatcgg gttcccggct cgccgaactc gttcggcggt taccgggtac
     9181 ccatgagcga gaagccggtg tccgacatgc gcgactatct ggacacgatg gacacagcgc
     9241 cgctcgccgg tgcgactcca gccacggcgc cgcgccgggt actcgcggca ctgggcccga
     9301 gaatgctcga tctggccgct gagcggacct cgggggcaca ttcgtacttc gtgcccgttg
     9361 cgcataccgc catggctcgt gagcgcatgg gcaccggcgc gtacctggcc gtcgagcagg
     9421 ccgtcgtact cgactccgac cccgagcgcg tcagacaact ccagcgtgca cacgtcggcg
     9481 cgtacctgcg ggcacagcac cagcgcaaca acctgcttcg cctcgggttc gacgagaccg
     9541 aactcgccga cggcggcagc ggacgcctga atgacgccct cgtcgccgga ggtgacatca
     9601 aggcaatctc cgcacgagtt cgagcccacc tggacgcagg cgccgaccac gtctgcctgc
     9661 aggtgctgac gccgagcccg ggggaactgc cgctacgcga atggcgtgaa ctcgcggcac
     9721 tcgtgggcga gcactagcgc cacccgattg ggggaaagcg ctttcacaac tgcgcgggct
     9781 accgtgcaga cgtcaagccc acacgctcga gaggagtagc tgatgatcga aaccggcgag
     9841 cgtgaggtgt ggtccactcc ggacttcgtc gagtacgaaa ccccgatgga agtgaccgcg
     9901 tacctcggcc ggatggagtg aacactcctt cacaccgtcg cgcccggccg cttcagaaag
     9961 cgcttccatg aaccggccgg gcgcgaccgg aggaacagtg atgccggact ccgcactgag
    10021 cgagaacgaa ttcgtcgccg ccctgcgcgg tctcgagccc cggtactggg gcgctcaccc
    10081 gtttcaccgc cgactgcacg gcggcgacct cggcaaggag gaactgcggg cctgggccgc
    10141 caaccgctgg tactaccagc gaaggctgcc gcagaaggat gccgcgatca tcagcaactg
    10201 cgatgtcacc gcgatccggc gccgctggct ggaccggatc gtctaccacg acggccgcac
    10261 cgagggtgag ggcggcgccg aacgctggct gcgtctgtgc gaagcggtgg ggctcaccag
    10321 ggcggaggtg ctcgacgagc ggcatgtggt tcccggcgtc cggttcgcgg tcgacgccta
    10381 cgtggacttc gccaggacga ggccgtggca ggaggcggtc gcatcgggac tcacggagat
    10441 gttctccgga catctcatgc gccgcagggt gagcgacatg ctggccagct acccctggat
    10501 cagcgacagt gacctggcgt acttcaccaa tcggatcggt gcggtgagtg gcgaaggcca
    10561 ggaggcgctg gacgtcgtcg tgcggtactg ccggacacgc gaacagcagg acagggccgt
    10621 cgcggcactg tcgttcaagt gtgacgtgct gtggtccatg ctcgacgcca tcgaccttgc
    10681 cgcgaagggg tgaagcgtgg accggccgag gctgcgccgc ggtgtccgcc tgacgtacga
    10741 caagacgcgg gacacgcacg tcctgttgta tcccgagggc gttctcgtac ccaatccgac
    10801 cgcggcgacg gtgctcgggc tctgcgacgg aaaccggacc gtgcaggaca tcgtggcggc
    10861 gctcggtcag cgctactcgg gcgtgcgcga gcacgaggta cacggcgtac tcgccagact
    10921 ggtggaacgg cggatggtcg aatggacgtg acgaacgcgg tgaacgcacc gctgggcatg
    10981 ctggcagagc tgacacatcg ttgtccgctg cactgcccgt actgttccaa tcccctcgaa
    11041 ctcactgccc gggaggacga gctcggaacc gacgagtggc tttcggtgct ggagcaggca
    11101 cgcgaactcg gcgtgctgca ggtgcatctg tccggcggcg agccgctgtc gagagccgac
    11161 ctgccgctgc tcgtgagcag ggccggtgaa ctcggctgtt acgtcagcct ggtgacaagt
    11221 ggtctcggcc tgaccgaatc ccggctcgcg gacctcgtgg accggggtct cgcccatgtc
    11281 caattgtccg tgcaggccgc cgattcggcg agggcgaacc tgctcgcggg cgcacgggcg
    11341 catgagcaca agatcaccgc ggcggggctg gtcacccggg caggactgcc gttgagcgtc
    11401 aacgtggttc tgcaccgcgc gaaccacgac cagctcgaag cgatgatcga cctggccgag
    11461 cggatgggcg ccgaccgtct cgaactcgcc aacacccagt actacggctg ggcactgcgc
    11521 aaccgcgccg cgctgcagcc gaccagggag cagttggccg cggccgaacc gatcgtccgc
    11581 gccgcgaccg agcggctgcg cgggcggatg gacctcgtgt acgtgctcgc cgactactac
    11641 gagtcctatc ccaagccgtg catgtccgga tggggttccc ggcagctgac ggtggcgccc
    11701 gatggcacgg tgctgccctg ccccgcggcc accgcgatct cgaccttgac cctggagaac
    11761 gtgcggaacc gcacgctggc cgacatctgg taccagtcgg agtccttcaa cgcctatcgg
    11821 ggcgaggact ggatgcgcga tccgtgccgc tcgtgcgacc ggcgctcgat cgacttcggc
    11881 ggctgccgct gccaggcgtt ccagctcacc ggggacgcgg ccgcgaccga cccggtctgc
    11941 acactgtctc cggaccgagc actggtcgag cggattctgg aagcaccgcg ggaggacgcg
    12001 gacttcgtca tgcgcggccc gcggtgaggg cagtgctgct gggcaccgcc gcgggcggag
    12061 gcctgccgca gtggaactgc gcctgcgcga actgccgtgc cgcccggcag ggcacgatcg
    12121 ccccgcgcgc ccaggactgc ctcgcgatca gcgtggacgg ccacggttgg tacctcctca
    12181 acgcctcccc cgacatccgc gcgcagatcc tgtcctgccc cgcgctggcc gcgggccccg
    12241 gaccgcggga cacgccggtc cgcggtgtcc tgctcaccga cggcgaactg gaccacaccc
    12301 tcggtctcat ccagctcaag gaggcagccg gactgcgagt gtgggcaccg gaggctgtgc
    12361 tgaacacgtt gccagcacgc gagatcgtcg gccggtacgc cggctgggaa tggctctcgc
    12421 cgagcaccgg cgcgccggac atcgacggcc tgcgaatcag cacactgccg gtcagcgaca
    12481 agcggcccaa gtacgcggcg ggctctccgg cggaagggcc atgggtggtg gcctatcgga
    12541 tctccgaccc ggtcaccggc agcgcactgg tctacgcccc gtgcctggcg ggctggccac
    12601 cgggcttcga cgagttctgc gcgggtgcga gccacgtgct gctggacggc tcgttcttcg
    12661 ccccggacga gatgtccacc gccacggaca ccgccgtcgg ttcccgcgcg cagctcgcga
    12721 tgggacacct gccgatgagt gggacgggcg gcagcctcga tcggatccgg cgggccgaaa
    12781 gcggcacacg ctggctgtac acgcacatca acaacaccaa tccggtgctc gacccccggt
    12841 caccggagtt cgcggagatg agcgccgcgg gcgccggtct cgcccgggac ggaaccgagt
    12901 tgcgcgtgtg actcccggtg tcctattcat aagtcgggtt atccacggtc aacccgcggt
    12961 catgcacgcg cctcaccagc agtgagtcgt cgcgaaccgc ccctactgtg gcacaaagag
    13021 cttgccacag cgggggccct tcctactgtg gcacaaaaag cnnnnnnnnn nnnnnnnnnn
    13081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnntgcc acagcggggg
    13141 cccttcctac tgtggcacaa aaagcctgcc acagcggggg cccttcgggg cgggccccgc
    13201 caactcactt gtgaataacc ctcccggtcc tacttgatgc ccgcggcgtc cattccgcgc
    13261 aactccttct tcaggtccgc gacctcgtcc cgcagcctgg ccgccagctc gaactgcagg
    13321 tcgcgggccg cctgcatcat ctgctcggtc atctgctgga tgaggtccgc cagttccgcc
    13381 cttggcatcg cgccgacgtc cttgtccgcc agcatccccg agctgcgcac tccaccgccc
    13441 tgctcgggct tcttcccacg cgaggagttg cgtccggaac cgccgatcgc cacgtcctcg
    13501 gagtcctccg cctcgtcgta gacacggtcg aggatgtcgg cgatcttctt ccgcagcggc
    13561 tgtgggtcga ggcctcgttc cgtgttgtag gcgatctgct tggcgcgacg gcggttcgtc
    13621 tcgtcgatgg cgtgctgcat cgagtcggtg atccggtccg cgtacatgtg cacctgaccg
    13681 gacacgtttc gcgcggcacg gccgatcgtc tggatcagcg aagttccgct gcgcaggaag
    13741 ccctccttat cggcgtccag aatggacacc agggacacct cgggcaggtc gagcccctcg
    13801 cggagcaggt tgatgccgat cagcacatcg aagtcgccgg accgcagctg ccgcaacagc
    13861 tccacccgcc ggagggtgtc cacttcggag tgcagatagc gcacccggat acccagctcg
    13921 agcaggtagt cggtgaggtc ctccgccatc ttcttggtga gcgtggtgac aagcacccgc
    13981 tcgtccttgt cggccctggt cctgatctcg tgcaccaggt cgtcaatctg cccctcggtc
    14041 ggcttgacga ccacctcggg atcgatcagg ccggtcggcc ggatgacctg ctcgacgaac
    14101 tcgccgccgg tctgccccat ctcgtacggc cccggcgtcg ccgagaggta caccgtctga
    14161 ccgatgcggt cggagaactc ctcccaggtc agcggccggt tgtccatcgc gctgggcagc
    14221 cggaagccgt gctccacgag gttgcgcttg cgggacatgt cgccctcgta catgccaccg
    14281 atctgcggga cggtcacgtg cgactcgtcg accaccagga ggaagtcctc ggggaagtag
    14341 tcgatcaggg tcgcgggcgc ggagccctcg gggcggccgt cgacgtgccg cgagtagttc
    14401 tcgatgccgg aacagaaccc gacctgctgc atcatctcga tgtcgtagtt ggtgcgcatg
    14461 cgcagccgct gggcctcgag cagtttgccc tgcttctcca gcgtggccaa ccggtcctcc
    14521 agctcggact ggatggtctt gatcgccttt tccatccgct ccggcccggc gacgtagtgc
    14581 gtggcgggga agatccgcac ctcggcgacc tcgttcacga tgtcgccggt cagcgggtgc
    14641 aggtagtaca gcttgtcgat ctcgtcgccg aagaactcga cccggatcgc cagctcctcg
    14701 taggccggga tgatctccac ggtgtccccc cggacgcgga aggtgccgcg ggcgaaagcc
    14761 aggtcgttgc gggtgtactg cacgtcgacc agtgcccgca ggaaggtgtc ccggtccacc
    14821 tcctcgccga ccttgaggct gctggagcgg tcgaggtagg actgcggggt gccgaggccg
    14881 tagatgcacg acacgctggc aaccacgatc acgtcccgcc tggagagcag gttcatcgtg
    14941 gcggagtgcc gcagccgctc gacgtcgtcg ttgaccgagg agtccttctc gatgtaggtg
    15001 tcggtctgcg cgatatatgc ctctggctgg tagtagtcgt agtagctgac gaagtactcg
    15061 accgcgttgt tcgggaagag gtccctcagc tcgttggcca gctgcgcggc gagtgtcttg
    15121 ttgggtgcca tcaccaacgt cggccgttgc acccgctcga tcagccaggc tgtggtcgcc
    15181 gacttgcccg taccggtggc gccgagcagg acgacgtcct tctctcccgc cctgatccgg
    15241 cgctccagct cgtcgatcgc cttgggctgg tcgcccgcgg gctggtagtc actgaccacc
    15301 gtgaacttgc cgtccgacct ggggacgtcg gagaccgggc ggaactcgga gtgcgcgagc
    15361 acgggatgtt cggttgcgaa agccacgtct ccagggtagg cgcgcccacc gacagtttca
    15421 gccggtggtg tccgtcgagc tgcgagcgga cccggcagga tgggcggcat gcccgacctg
    15481 cacccaccca agaccgagat cttcgacgtg cccggcatga gcaacaccga cccgaagggg
    15541 atcgtccgcg acgtcgaacg gttccaggtc gagtcgttcg ggctgtacat ggccaggccg
    15601 actccgggca ggcgccagtt ccactacctg gagtcgtggc tgctgcccgg ccttggcctg
    15661 cggatcacgg acttctggtt caccgagggg cacgagcacg accaggactt ctacctcgac
    15721 gtcgtggaca tcgaacgcca cgatgaccgg tggcgggcca ccgacctcta cctggacatc
    15781 gtgctccgcg acgcccgcgg cctcgacgta ctcgactccg acgagctgct cgccgccacc
    15841 agcgcggacc tgctaccagc ctacacggca cgccaggcac tggataccac gttcaccacc
    15901 gtcgacggcc tcgcccgcca cggctaccgc ctgcaggaat ggctgcgcac gatggacatc
    15961 accctgacct ggcagcgcca ctaaccgccg gcccgagttt gcagttccgg agcccgagtt
    16021 ggcagttccg cggccgtcag gcgggactcc acccggtccg ctccgcccac tcctcggccc
    16081 gggtgaacgc gtcgttgacc cagtcctgct tctcctccgc gtacggctgt gtcgtgccat
    16141 cgcccgcatg cgcgcctgcc agccgccgct tgacctccgc gtaggcggca agctccggtg
    16201 gattcgcccg cagccagtcc cggaacagca gcgcgaggcg ccacgccggc ccttcttcgg
    16261 ctcggacgtg caggttcacc ggacggaccg gatccgcgcc gaagtggaac cgcttgtccc
    16321 agacggcgga accggccgta ccgtcctgcg gatcgtcgaa ccagtgcccc tccgccctgg
    16381 ggaaccccgc gtcggacaag gcgtcggcga gctcgtccgc gacatccagc gtcggcacgg
    16441 tcaactggag gtcgagtacg tccttggccg gcaggccggg gaccgcggtg gagccgatgt
    16501 gatcggcccg cgcggctctg tcccccgccg ctgcccgcac cctgccgagc acgcgttcgg
    16561 cctgacctgg ccaggtttcg tcgtagggag ataccagcgg agaacggggt ggacgcggtt
    16621 tacgcagccg caggttcgcc tcgaacggca ccagcctgtc cgcccacagc gcgtcgacct
    16681 ccgccagcac gatgtcccgt gccccgccgt tgtccagcca cacgtcggcg gcggctcggc
    16741 gttgttcgac actcgcctgt gccgcgatcc tggccctggc gtccgcctcc gacatgccgc
    16801 gggcctccac gagcctgcgc acccggacct cctcgtcggc gtcgacgacg acgacgaggt
    16861 ggtagtgcgg ggcgagcccg ccctcgacca gcaacgggat gtcgtgcacc acgatcgcgt
    16921 cgggcgccgc gttccgcatc agctcggcgg tccgcgcgcc gaccctggga tggacgatgc
    16981 cgttcagcct ccgtcgcgac tgctcgtcgg cgaacgcccg cgccgccagc gcggcccggt
    17041 ccagcgcgcc gtccctggtc agcacatccg ggccgaaggc ctcgacgatc tcggcgagac
    17101 cttccgtgcc gggctccacc acctccctgg cgaggagatc cgcgtcgatc agtaccgcac
    17161 catgctcgac caacctggtc gcgacggtcg attttccggc accgatcccg ccggtgagtc
    17221 ccactcgcag catgacgggc attcaatcag ccccggacaa catccgcgaa ggcggtgatg
    17281 ttcccgtgct cgggcccact cagaggcaca tcacgagacg ttatgcaact gaagtgggtg
    17341 acacgccggg aatttcacac catttggctt cccgattgcg taccgtgcgc ggcgtaggca
    17401 atcgcccact cggaggaacg atgccagaca gcaggcacac tggtaagcac cggctcggaa
    17461 cgccggggct ggtgcattgc gtcatgcatc gtcccgtcgc agaggcgttg accgagtatc
    17521 gccgcacctg gctgaccgca cttctggtgc cggccaagca cagcctcgcc ggcctgcgtc
    17581 gcagggctcg cgccgccgct cacgagcacg cctgggctcc cgccaccacc tgacccaggt
    17641 cgcggctctc tccggctcaa ccccggctca ttcctggccg cactcccgcg tccacctgcc
    17701 ctcaccaagc ttggtgcgcc tgcaagtacc accaagcaag atcaagagcg tcgtcagctg
    17761 ccgccaaccc gcatgcctcg gtagcagttg gcggcgatgt cgatcttgct tggtggtact
    17821 tgcagacact ccaagtcctg aaacgtgggg tgcgcacggg ggaagccccg gtccgatatg
    17881 gaccggggcc tctctcgtgg tgtcgtttgt caggcgctca gggcctcacg cgccaccgga
    17941 cagcttctca cgcagcgcgg cgagctgctc gtcactggcc agcgtcccac cggtgctctt
    18001 cggcgccgag tcggacggcg tggaggagta gctctgctcc ccgccaccgc cgctgctgct
    18061 ctcgccaccg ccggcgatcg cctgggcagc cgcttccgcg tcggcctcgg cggccttggc
    18121 gatctgcttc atgtgctgct cgtagcgagc gtgtgcctcg gcgtactgac gctcccactc
    18181 ctcacgctga gtgtcgtagc cttcctgcca ctcctgcgtg tcggggtcga agccctcggg
    18241 gtagatgtag ttgccctgct cgtcgtagtc ggcggccatg ccgtactgcg tcgggtcgaa
    18301 ctcggcgtcg gtggtgaggc cctcgttggc ctgcttcagc gacagcgaga tgcggcgacg
    18361 ctcgaggtcg atgtcgatga ccttgaccat cacatcgccg ttgacctgga cgacctgctc
    18421 cgggatctcc acgtggcgct cggccagctc ggagatgtgc accaggccct cgattccctc
    18481 ctcgacgcgg acgaacgcgc cgaacggaac gagcttggtg accttgcccg gcacgatctg
    18541 accgatcgcg tgagtacggg cgaactggcg ccacgggtct tcctgggtgg ccttcagcga
    18601 cagggacacg cgctcgcggt ccatgtccac gtcgagcacc tcgaccgtga cctcctggcc
    18661 gacctcgaca acctcggacg ggtggtcgat gtgcttccag gacagctcgg aaacgtgcac
    18721 caggccgtcg acgccgccga ggtccacgaa cgcaccgaag ttgacgatcg aggagacaac
    18781 gcccttgcgg acctgcccct tggccagcgc gttgaggaac tcgctgcgga cctcggactg
    18841 ggtctgctcc aggtaggcgc gacgggaaag caccacgttg ttgcggttct tgtccagctc
    18901 gatgatcttg gcctcgagct cgcggcccac atacggctgc aggtcgcgaa cgcggcgcat
    18961 ctcgacgagc gacgcgggca ggaagccacg gaggccgatg tccaggatga gaccaccctt
    19021 gacgacctcg atgacggtgc cgctgaccgg ctcgtccttc tccttgagct cctcgatcgt
    19081 gccccaggcg cgctcgtact gcgcgcgctt cttggacagg atcaggcggc cttccttgtc
    19141 ctccttctgg agaacgaggg cctcgacctc atcaccgacg gtgacaacct cggccgggtc
    19201 gacatcgtgc ttgatggaaa gctcgcgcga ggggatgacg ccctcggttt tgtacccgat
    19261 gtcgagcagc acttcatcgc gatcgacctt gacgatggtg ccttcaacga tgtcgccatc
    19321 attgaagtac ttgatggtct tgtcgatggc tgcgaggaag tcttcctccg tcccgatgtc
    19381 gttgatcgcg acctgctgcg ccggggcggt ggcggtcggg gcggtggttg tgtcggtggt
    19441 cattaggcgg gttgctccgg taacggcttg ggattagtgg gtgtgcagtt tgcgcgcgcc
    19501 gtgggagtca agggcgacga cgaaaacgcg ttcggcgagg aacggtcgca agcatcaccc
    19561 gaggagcgcg acccacaacc agcaagaact ccgtccagca cgaacactgc tgagtcaaag
    19621 gcagcgcgaa cccactgcgc taacacgtat cctacgcggc gctccgacgc gggcacaacg
    19681 agggtcaccc tcgtccccgg cgcggccacg acacggacta cccggcagga tagcgggcgt
    19741 ggtcactccc ccgccgccaa caccgcggac gccgccaaca ccgcagacag cgcccgccgc
    19801 cgaccggcac gagcgggccg agcaacgcct gcacacagcc ggggtcgcgt accggccggt
    19861 cgactccgcc gaagcggcct cggccaacct cgcctggtgg gatgccgacg cggacgacta
    19921 ccacgcgacc cacggcgagt tcctcggcga gagcgacttc cgttggtgcc cggaggggct
    19981 gctggaagcc gacgcgcgcc tgctcggcga ggtccgggac accgacgtgc tcgaggtcgg
    20041 ttgcggctcg gcgccgtgca cccgctggct gcacacccag ggcgcccggg ccgtcggcgt
    20101 cgacctctcg ggcggcatgc tgcgtcacgg tctcgccgcg ggcgagcgca ccgggatccg
    20161 ggtgccgctg gtccaggcca acgccgagcg gctgccactg gccggcgaca gtttcgacac
    20221 cgcgtgttcc gcgttcggcg ccgtgccgtt cgtcgcctcc gtggagacac tcttcgccga
    20281 ggtcgcaagg gtgctccgcc ccggcggccg ttgggtgttc gcggtgaccc acccgatgcg
    20341 ctggatcttc ccggacgatc ccggccccac cggactcacc gcgacacagc cgtacttcga
    20401 tcggacgccc tacgtcgagg tcgacgccga cggccgcgcc acctatgtgg agtatcaccg
    20461 cacgatgggc gactacgtcc gcgcgctggc cgcggccggg ttccggttga cggacctgat
    20521 cgaaccggaa tggccggaag ggcacacccg cacctgggga cagtggagcc cgttgcgcgg
    20581 caagctgttt ccgggcaccg cgatcttcca cacggtgaaa gagcggcaaa cgtgaccgac
    20641 cggacggccg agcagtcgga gcacttcgcc cggatcgacc cgttgctgcc gccggtgacc
    20701 gaccttcccg agggcgagca cctcaccgcg gtgctccccg acggcaggga ggtgcacggc
    20761 gtgctctacc gggccgtgta cggcgccggg tcgccggaga gcctgtgggc ggccagggag
    20821 aactgggaac tcaccccgct gatcggaaac accggggccg agggaatgtc agccctgctc
    20881 ggagcgctgc gccgacggct ggatcgcgag ccgcccacgc aggactcggc ctgcgccgtc
    20941 gcgtggccct cgcgcgacgc ggaggcgacg cgggcgctgc tcgaccacgg cctgcaaccg
    21001 ttgaacgcgc tggccgtgcg gcccaaccgt cccgcacccg aggtcgacgt tcccggcgtg
    21061 ctggtacgca gggcacgtcc cgtggacgaa gaagagatca tcgcgttgcg gatgaacgag
    21121 ctccgctact cggcgctggt cgggccgaac gtggtgcgcg agaacgccac cgagctgatc
    21181 accgccgagg tacggcgcgg actggtgttc ggcgggcgta cctggatcgc cgagtccggc
    21241 ggggcggccg tcgggctcgc cagctgcggc tggacgaccc ccgccgcggg aagctcgatc
    21301 gcgggacgcc tcggctgggg ccgctggggc tacgtcggca cgctgtccgt catcgccccc
    21361 gcccgtggcg gcggggtggg acaggcgctg atgtccgtgg cacacgatca gctcaacctc
    21421 gacgacgtcg aaggcacttt tctcttctac agccccacga acccactgtc accggtgttc
    21481 tggcaccgcc agggataccg cccattgtgg acaatgtggg agattcgccc ggcctcggcg
    21541 ctgcgctgac cgctcgcgtc acccaaaggg gtcagatcac cccccgccag cttgccgagg
    21601 gagtcacagc agggctaatt tgaactgacc ggtcagttca aaaggagtct cccatgcagg
    21661 tgcacgccga tcgcgtgtcc gtcgacggcc cgcacggcac gctgctgccg tccacctcgt
    21721 tcaccgtctc cagcggtgag ttcgcgctgg tccacggcga tcccggcacc ggactgaccg
    21781 ctttcggcct tgcgctggcc gggcggttgc gcccgacgac cgggcggatc accctcgacg
    21841 gctcccccga cgcggcggca ctgcgcaggc aggtcgcggt cgtcgacgcg cccggtgtca
    21901 gcgaacccga ggaggcactg gcgcttcggg tggtggtcgg tgaggaactg gcgctggccg
    21961 ggcggcaggc agaccgggag agcgtcctgc gctggctcgc cgagcacgac gtggcggcct
    22021 acgcgga
//
