LOCUS       NZ_FOKG01000014        24437 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Amycolatopsis marina strain CGMCC 4.3568, whole genome shotgun
            sequence.
ACCESSION   NZ_FOKG01000014
VERSION     NZ_FOKG01000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Amycolatopsis marina
  ORGANISM  Amycolatopsis marina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900111885.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:41:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,708
            CDSs (total)                      :: 6,643
            Genes (coding)                    :: 6,572
            CDSs (with protein)               :: 6,572
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 22 of 71
            Pseudo Genes (incomplete)         :: 62 of 71
            Pseudo Genes (internal stop)      :: 4 of 71
            Pseudo Genes (multiple problems)  :: 15 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:06:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 125956
            Orig. end                         :: 150393
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOKG01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24437
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24437
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24437
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14437](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14437)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(204..350)
                     /locus_tag="BM199_RS33955"
                     /old_locus_tag="SAMN05216266_114122"
     CDS             complement(204..350)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM199_RS33955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216266_114122"
                     /product="hypothetical protein"
                     /protein_id="WP_177242739.1"
                     /transl_table=11
                     /translation="MIRRVARGLLHDVLITGETAAANEAMETFVDLLLHDGEQETGPSH
                     AGK"
     gene            complement(347..835)
                     /locus_tag="BM199_RS22305"
                     /old_locus_tag="SAMN05216266_114123"
     CDS             complement(347..835)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646179.1"
                     /locus_tag="BM199_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114123"
                     /product="hypothetical protein"
                     /protein_id="WP_091675251.1"
                     /transl_table=11
                     /translation="MEDVLLSVHVLAAIVFVGGSAVAASLFPRYAPVAAPVPATEPAQP
                     GASQTTSGERSLAVALALHRITRGYSVVAIIVPVVGMVLASLQGRMGEIWIIVSMVLTA
                     AAGLLLALQIYPRQRDALMRSATERGLRTLSMYAGFYNLLWAAVVVLMIVRPGAHTGA"
     gene            complement(946..1395)
                     /locus_tag="BM199_RS22310"
                     /old_locus_tag="SAMN05216266_114124"
     CDS             complement(946..1395)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006239911.1"
                     /locus_tag="BM199_RS22310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114124"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_091675252.1"
                     /transl_table=11
                     /translation="MTDEKDSSTPPVTSTSIVVLTLARRIESELNTTLAPLDLTVSKLG
                     LLGHISGLPGVSFSELARMSGTTVQSVHAAVKALAAAGLVRDNTARPGSASTIAVTPEG
                     AQLLDAARAAVAQVDDRMFGPDADPIQRQVGAAVRAAFEGESAAN"
     gene            1602..2504
                     /locus_tag="BM199_RS22315"
                     /old_locus_tag="SAMN05216266_114125"
     CDS             1602..2504
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024981.4"
                     /locus_tag="BM199_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114125"
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="WP_091675253.1"
                     /transl_table=11
                     /translation="MEQNPLVEVGLPVALFLIMIGIGLTLTSKDFAREARDPRGVIVGT
                     LGQIVLMPALAFLIAYLLSLPAAIAVGLVIIAACPGGTTSNLIAYLARGNVALSIVLTV
                     LASLITIVTLPIAANLALRWQPAASDVAIEVPVLRTIALLVVIVLVPVAIGMALRARWP
                     ERAAALERAVSLFGGVVLAVLIVAIAISLGADIWTYLRQAGIAALLLNLGGLAVGYGIM
                     RLARLSFESRLAGAIELGIKNATLGILIAVNVIGSEALAVPAAVYGVLMYVSAVGVVAY
                     GRRRGRQASAVGDTVPKPL"
     misc_feature    2570..2583
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.58"
                     /tool="antismash"
     misc_feature    2692..2708
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.46"
                     /tool="antismash"
     gene            2803..4353
                     /gene="mptB"
                     /locus_tag="BM199_RS22320"
                     /old_locus_tag="SAMN05216266_114126"
     CDS             2803..4353
                     /codon_start=1
                     /gene="mptB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073566.1"
                     /locus_tag="BM199_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114126"
                     /product="polyprenol phosphomannose-dependent alpha 1,6
                     mannosyltransferase MptB"
                     /protein_id="WP_177242740.1"
                     /transl_table=11
                     /translation="MSYELRLAQARSGRAATCLRWTGFAGLLLLVVMVFVAAGTAGRAN
                     SGTVFDWLGGLPFVTLTVAVAGMGLFILAWLFLGRLTWPDGRHTVTGRWLRRTLALWSA
                     PLMFVPPLFSGDVHSYLAQGAIAARGGDPYAVGPATGLGVDAELTRNVSSYWVDTPSPY
                     GPLFSAVERTIAQISAENVFTGIALHRVLEVAGLVAIVWAVPRLARRAGVPAAPALWLG
                     VLNPLVLWHLVAGIHNDSLMLGLMLVGVELALAALSGARIAWLPLCSGVGVIALAANVK
                     LVAVIALATVGAELARRWGAGLKHLLVSAAAMTAALALVTIVVSAGAGLGFGWVRTVST
                     STQVNSWLAPTNWAGFLVGGIGSWFDVDITQSAISVGRLVGAVLAVVAIAVLIWRQLRG
                     RTGALQTLALVSLAIIVFGPVVQPWYVLWASVPFAVCLGRGRARGMVTGATAVLALALP
                     PMGGDFGGRIGDLVLAYVVASVVVAGAAYVLQRRLFPARTVLATEAEPKSARELTPSV"
     misc_feature    2815..2817
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4355..5512)
                     /locus_tag="BM199_RS22325"
                     /old_locus_tag="SAMN05216266_114127"
     CDS             complement(4355..5512)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668892.1"
                     /locus_tag="BM199_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114127"
                     /product="C45 family peptidase"
                     /protein_id="WP_091675254.1"
                     /transl_table=11
                     /translation="MNTSNDIVAGGGEADFMTVRQLTAHGSQIDIGRFLAEEARSGYGW
                     RPQPADPLRAGARLDWFERNWPQHHARMLGAAETLGIDIRSAYLDGLTGTPEGSACSST
                     FYPPQVTENGHGLLGRNYDFFTTSASALFAMLSGRTVEDTGPPMAGRPYVVTTVPDDGP
                     ATTVLTMNELDCCMEGINEYGLAVALLIADSGTAGAPVVDEPQVGLSSTQLPRFVLETC
                     ATADEAKRALLGAKQYDLGTPLHYLIADAEGNSFVWEHGPGGDEHIVESDSGALCVTNH
                     LLHRHPDPAALPEDTEETLRTYERYRMLRKRATEPATTGSALRSTLDEIGFTAANSMLY
                     PMRTLWRSVFDLTERTMSTRFYLGELPDGEARHSEELTFGPAITR"
     gene            5652..6563
                     /locus_tag="BM199_RS22330"
                     /old_locus_tag="SAMN05216266_114128"
     CDS             5652..6563
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644134.1"
                     /locus_tag="BM199_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114128"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_091675255.1"
                     /transl_table=11
                     /translation="MKPSVPPYLRIAGEIGDRIARGELRPGDRVPSARLIMREWGVAMA
                     TASKVLTTLRHDGLVEVRPGVGTVVLTAGRATPAVRVPTEGTLTTARVVEAGIAVADAD
                     GLDALSMRQVAADLGAGVMSLYRHVANKDELIRHMIRAVFAERELPAPAPEGWRAKLEL
                     VSRVQWELYRRHPWLAAQVSMTRPMLLPEMMAHTEWVLAALEGLGLTRLEMTREAVALP
                     AFVRGVALSVADEIEAERNTGLTSQQWWLSLRHEVEALYGRFPRLVLMEDDVAKDLDAV
                     FAHGLARHLDGLGVAIRHRRNR"
     misc_feature    6625..6638
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            6773..7732
                     /locus_tag="BM199_RS22335"
                     /old_locus_tag="SAMN05216266_114129"
     CDS             6773..7732
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639224.1"
                     /locus_tag="BM199_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114129"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_091675256.1"
                     /transl_table=11
                     /translation="MCYGFDGDAALGHSLTERGMSRRTMLRGALTGAVGAGLLAAGLGG
                     APAHAAGRATGRPRVPPGLISIQLWTLRDALWGSPGFDGTLRAIADLGYPKVEQALGYF
                     GRTAGELRAFYDDLGISATSSHDGISENRQALETKIDNAATLGQSFMVVPYLNSAKADD
                     WRRWAEEMNREGEAARASGLRYGYHNHAHEFTTDLGGGTTPWDVLTAELDPSLVHLEID
                     LYWVVRGGIENGDGAADPEGFAIDVIRSAPQRVLQYHVKDRHADTGDMADLGTGMIDFP
                     RIFRAHSVLEYIVENDTPDVSPLQSAEVGYRYLRGLRY"
     gene            7816..9930
                     /locus_tag="BM199_RS22340"
                     /old_locus_tag="SAMN05216266_114130"
     CDS             7816..9930
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153636.1"
                     /locus_tag="BM199_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114130"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_091675334.1"
                     /transl_table=11
                     /translation="MRASRMVAVLAAAGAALAVAQPASTAEPLRPDDSAFQKVTLNDTP
                     GEPVDLAVVPDGRVLHTTRAGELWLNDPDSGLNTLAAELDVYSHDEEGLQSVAVDPGFD
                     GKSNRWVYLYYAPPMNTPTDDPSTPDINEGDAPTTGTAADFAPFEGIQRLSRFQLVGDK
                     LDLSTEQQILEVKEDRGICCHVGGDIVFDGDGNLYLSTGDDTNPFESDGYVPLDERANR
                     NPAFDAQRTSANTNDLRGKVLRIQVQQDGSYSIPEGNLFEPGTAGTRPEIYLMGLRNPF
                     RIEVNQETGELYVADYSPDAGSPDPERGPAGQGRWIATSEAGNYGWPYCVKPDMPYVDY
                     DFATGQSGEPFNCAAPVNESPNNTGLTQLPPVEQPEMWYSYGESEQFPELGTGGIGPMA
                     GPAYDFDRAATRGRAPVAWPEYYDGAPLFYEWTRDYIKAFRQNDSGGVASIEDVVPSVD
                     VSGVIDMEFGANGALYVLEYGKGYFAENPDAQLARIDYIGPNGNHTPTPKASADVTNGQ
                     APLTVSFSSDGTHDPEGDRLRYEWDFDSDGDVDSRSSNPTHTYRENGVYTSSLKVTDVG
                     GKHRGRSASAEVEIVVGNTAPVVEFVKPVDGQAFEFGDVIEFEVSVTDDQTVDCSQVQV
                     TYILGHDDHGHPQTTASGCTGTIQTTIPGGHDPEHDELRGVFHATYTDPGADGVPALSG
                     DAEIVLQPHG"
     misc_feature    complement(7825..7838)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            complement(10001..12235)
                     /locus_tag="BM199_RS22345"
                     /old_locus_tag="SAMN05216266_114131"
     CDS             complement(10001..12235)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684951.1"
                     /locus_tag="BM199_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114131"
                     /product="Geosmin synthase"
                     /protein_id="WP_091675257.1"
                     /sec_met_domain="T1TS (E-value: 2.3e-81, bitscore: 268.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSFTLPEFYTPHPARMNPNLERAREHSTQWAKRMGMLDAPKPSG
                     GLVWDEEKLAQMDYALMCGYTHPDCDSLALDLITDWYVWVFFFDDHFLEQFKYSRDLAG
                     AKEYLDRLERFMSAPGETPPEPENPAEAGLRDLWERTVPSMSEGWRRRFTTTTHNLMIE
                     SMWELDNIDRGRIANPIEYMQMRRRVGGAPWSANLVEYAVGAEIPDRIAATRPMRVLSD
                     TFADAVHLRNDLFSYQREVQEEGENSNAVLVFERFLDCSTQQAAELVNDLLTSRLQQFE
                     NTALGEVPALLAEHAIPPHEQGGVAAYVKGLQDWQSGGHEWHARSSRYMNEEAASIAPN
                     PLGGPTGLGTAAASLFTQGLRHRGPRHAHRPFTPVGHLPLPDFYLPYPVRTSPHLDAAR
                     KYAVGWAEWAGMFAPVPGTEFGAVWDEEKFTGFDLAHCAAMIHADASQVQLELSSDWLA
                     WGTYGDDYFPAVFGSSRNLSGAKLCQERFAAFMPLDAGETPEPVNALERGLADLWQRTA
                     GPMSLAARTEFRTAVEDMTSSWLWELENQAHNRIPDPIDYVEMRRRTFGSDMTMSLARL
                     SANEPIPAELYRTRVMHELDTAAQDYACFTNDLFSYQKEIEFEGEVHNMVLVVENFLNV
                     DRLAARDVVAGLMAERMREFEHLVKHGLPAMFDEYDLDVQVRGALTRHVDDLKDWMAGI
                     MEWHRTCVRYKEEDLRGGAATGPREKFSFHPTGLGTSAFRPPGRSALLHG"
     gene            complement(12311..13303)
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="BM199_RS22350"
                     /old_locus_tag="SAMN05216266_114132"
     CDS             complement(12311..13303)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666921.1"
                     /locus_tag="BM199_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114132"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_091675258.1"
                     /transl_table=11
                     /translation="MPGHEARVHIDVQDPAWRAVAGPRTILLASPRSFCAGVERAIDIV
                     DELLRRRGAPIHVRKQIVHNTHVVGELEARGAVFVDDLDEVPSGSTLVFSAHGVSPAVR
                     DTAAERGLEVVDATCPLVTKVHAEARRFAGRGDTVILIGHEGHEEVEGTFGEAPEHTVL
                     VQTADEVATLDVPDPSRVSYLTQTTLAVDETVEVIAALRKRFPQLRGPASEDICYATTN
                     RQDALRAIAEEADLVLVVGSANSSNSVRLVELAQRCGTAAARIEDVGELRPEWLDGVGV
                     VGLTAGASAPPRLVDAVIEALGALGPVSVAQRETAHETIRFTLPPSARQ"
     misc_feature    13262..13276
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(13346..14437)
                     /locus_tag="BM199_RS22355"
                     /old_locus_tag="SAMN05216266_114133"
     CDS             complement(13346..14437)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073756.1"
                     /locus_tag="BM199_RS22355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114133"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_245788544.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-65, bitscore:
                     215.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATNMTNVPGTEQATDDAVGARPPADLLRWSQDTVRPALRAAVD
                     TLPRPVRDIAAYHLGWLDEHGKATEAATGKAVRPALALLAAEAVGGTPQAAVPSAVAVE
                     LAHNFSLLHDDVMDGDVTRRHRPTAWAVFGTAPAILTGDALLTLALDVLAAAGGPAARS
                     MRILAAAVQELVRGQAEDLAFERREEVSLDECRRMAEGKTGALMGCAAALGAVAADGSL
                     EQVRQLRGFGEHLGLAFQFVDDLLGIWGDPAATGKPVYSDLKSRKKTLPVVATLCGSTK
                     QGGSAEPGRALAALYAGERPLSEADLRRAAALIDEAGARDWSQASADDLLRRALGHLRA
                     ARPEPRAAAELATLAGLLTRRDH"
     misc_feature    complement(14318..14320)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14442..15842)
                     /locus_tag="BM199_RS22360"
                     /old_locus_tag="SAMN05216266_114134"
     CDS             complement(14442..15842)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225101.1"
                     /locus_tag="BM199_RS22360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114134"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_091675259.1"
                     /transl_table=11
                     /translation="MTATEPIETTGQRALSSLGTAAARNLATTTKSVPQMQGITSRWLL
                     RMLPWVETAGGTYRVNRRLSYAVGDGRVTFTNIGTAVQVIPAELGELPPLRGFTDDPTL
                     AELAGRFEQQELGAGEVIVEFGHQRDHVYLIAHGKVNKLGTGSYGDPTVLGTLADGDHF
                     GDETLLDSQSIWEFSVKTITPCTVLALPLAEFEAVVQRSEPLRRHLDEQRRQTSASQNA
                     YGEAEVDIASGHEGEADLPATFVDYEVRPREYELSVAQTVLRVHTRVADLYNQPMNQLE
                     HQLRLTIEALRERQEHELVNNPDFGLLHNADLKQRIHTRNGPPSPDDLDELLSRRRKTE
                     LMLAHPRTIAAFGRECNSRGLYPSSMELKGHQVTSWRGVPILPCDKIPVSEHNTSAILA
                     MRTGEDHHGVVGLRQTGLPDEYEPGLNVRFMGVDDKAVMSYLVSTYHSAAVLVPDALGI
                     LENVEIGR"
     gene            complement(15909..17297)
                     /locus_tag="BM199_RS22365"
                     /old_locus_tag="SAMN05216266_114135"
     CDS             complement(15909..17297)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020423482.1"
                     /locus_tag="BM199_RS22365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114135"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_245788558.1"
                     /transl_table=11
                     /translation="MDDEERRPSSLATTAARNLATTTKTVPQMQGITSRWLLRALSWVE
                     VPGGAYRVNRRLRYAVGDGRVTFSSDGAVIRVIPQELRELPLLRGFDDEEVLRELAGRF
                     VQREYQPGDLLAVQGQPVDEVFLLAHGKVNQLGAGAYGDHTVLRTLADGDYFGGRALTR
                     SPGDWDCTIKAVTSCTMLALERQALEGLDERGAALRAHIDRAASAPSASQNAYGEAEVD
                     IASGHEGEADLPATFVDYEVRPREYELSVAQTVLRVHTRVADLYNQPMNQLEHQLRLTI
                     EALRERQEHELVNNPDFGLLHNADLKQRLQTRSGPPTPDDLDALLAMVWKEPAVFLAHP
                     RTIAAIGRECNRVGVYPMNTDYGGHQVPSWRGVPILPCNKIPVTGTRTSSIMLLRTGEA
                     NQGVIGLHRTGLQDEYEPGLNVRFMGINEQAIMSYLVSTYHSAAVLVPDALAVLENVEI
                     GRES"
     misc_feature    complement(17472..17486)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.23"
                     /tool="antismash"
     misc_feature    17548..17558
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            17850..18611
                     /locus_tag="BM199_RS22370"
                     /old_locus_tag="SAMN05216266_114136"
     CDS             17850..18611
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666926.1"
                     /locus_tag="BM199_RS22370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114136"
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_091675261.1"
                     /transl_table=11
                     /translation="MNIYLSGVIWVVGASAVAGVSAYVVRRFGQDEGRPGNNDAAGQVF
                     TIVAGLHAVLVAFVLIAQFDAVTQARKGSYTEAQALVAAAWSADSLPEPTRSQVRAHSA
                     DYASTVLDEEWPQMRADTEVSRSGWEQLDRIQVDLAKAKADENWQEERKTRATEALTVV
                     AEARQQRVQQANGDQVGAVVWFALILGSVISTLLPNLFGGTRLGTHVIIVSTLAGTITL
                     LLFAIYQLQNPFSGGAVVEPDAFRNALERLR"
     gene            18617..19468
                     /locus_tag="BM199_RS22375"
                     /old_locus_tag="SAMN05216266_114137"
     CDS             18617..19468
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM199_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216266_114137"
                     /product="hypothetical protein"
                     /protein_id="WP_091675262.1"
                     /transl_table=11
                     /translation="MSPDALPGGRGSAVLLVTILLVLFAAPQGLAEYSPAQPAADCTVM
                     MVRSDSGSGVSTISRVDLPSATVTELPALPQQVDALGYAQSQSLTYGVARSGSAVTIDR
                     DGKLIDLGAIRFGDPPVRWKGLGGASAGTVVGDRWYIRKSGFLYIVDIERRSPTYLNIL
                     RATALAPPDLSALGDFDAHPHEGVLHGVSVSGKGDVTAVRIDIGTGRITPNRDVQLPGA
                     DAFGSVVFGPDGSGYLLADRSSGQRQPVPAFPRRPRCDHRDRGGTVVVDLGHGRVPGTT
                     ST"
     gene            19554..19802
                     /locus_tag="BM199_RS22380"
                     /old_locus_tag="SAMN05216266_114138"
     CDS             19554..19802
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM199_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216266_114138"
                     /product="hypothetical protein"
                     /protein_id="WP_091675263.1"
                     /transl_table=11
                     /translation="MPPDPTSAPEPPSAVPTPESAPATSATSFAPPMKRPPAWSNEQEP
                     YAAADNGSTEKKRRWGLTVLLLVVGGAAVVRAAGRTR"
     gene            19842..21758
                     /locus_tag="BM199_RS22385"
                     /old_locus_tag="SAMN05216266_114139"
     CDS             19842..21758
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0007154 - cell communication [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636573.1"
                     /locus_tag="BM199_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114139"
                     /product="Calx-beta domain-containing protein"
                     /protein_id="WP_091675264.1"
                     /transl_table=11
                     /translation="MSIRRRRPKWCVLLLVVLVVSLGVAWPAVADDGPPGVHPSAVDLT
                     LAPGESREVGKRITTSSIPSNPDLHFLADTTSSMGAAIAGVRQSAGTIMDTVRRAQPSA
                     RFGVAEYRDVHADLVSYRVNQTLTADPGKVRAGIDQWVAQGGGDAPEDAINALYRLAVD
                     SRAVRTDTTRIVAWFGDAPSHDPSGGHSLQETVAALQEANIRVVAVDSAGLDAHGQASA
                     VTSGTGGVLLRGVAPDAIADAILRGIAAVEVTVAPHVTDCAPELSVLNSPEALVVPSGS
                     VARFTEKITVAPDAAPGTYRCTVDYLVDGVSRGYVERNTVHVPGLRIDDSTVREGAAGT
                     APATFTVTLAPPGGRPVTVDYETADATATTPDDYAKTSGSLTFEPGETTKTVVVGVHGD
                     LVDEKNEKFTVRLSAASGAGMVDPEGVGTITDDDRDGTFGCTGTSAELAGIAPVRANPA
                     GYPCRDDDSAMPGGDLRAGGIVVRARELTATANRTPDDLAVPPGAGDTALGTAGLSSAT
                     VTAPGLTIEFGVIRAEASVTCVADAGGLKPELASTSNIARLSINGVPVDVGSVPSTIPL
                     AIGALTLNDTSTDGTTVRQRAVTLTTKDAVLVLAEAGAGTTSSSLHPDGSACRSLEHFR
                     RMR"
     misc_feature    20436..20438
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    21780..21795
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.37"
                     /tool="antismash"
     misc_feature    complement(21801..21812)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.58"
                     /tool="antismash"
     gene            22067..22300
                     /locus_tag="BM199_RS22390"
                     /old_locus_tag="SAMN05216266_114140"
     CDS             22067..22300
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM199_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216266_114140"
                     /product="hypothetical protein"
                     /protein_id="WP_091675265.1"
                     /transl_table=11
                     /translation="MTATERVTGTRDEHFDLTSVLYHTLQEAETLQQYINDARQAGDEE
                     AAELFQELRDHDQHCAGQVKKLLAQRFQQASS"
     gene            22516..23745
                     /locus_tag="BM199_RS22395"
                     /old_locus_tag="SAMN05216266_114141"
     CDS             22516..23745
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="BM199_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216266_114141"
                     /product="MFS transporter"
                     /protein_id="WP_218160402.1"
                     /transl_table=11
                     /translation="MVGWSALMVAATAPGQTAAVSVFIDPMIAELGVSRSAISTAYLIG
                     TLTGAVAMPFVGRMLDRFGVRRVMAGIGIVFSAALCSLAAVSSIVGLTAGFVVIRMAGQ
                     GALGLAATTAVALWFDRRRGTAVGIVSAVGASAISLAPVLLESLVADWGWRRTWLAEGI
                     AIAVLVVPVALLAMRNRPADLGQQPDGKAADQTTPPRAIWGVTRAVALRTPFFWVVTAG
                     IAATGLLSTAINFHQISLLTARGLSTVEAAANFLPQTVANLLGTLLTGMLADRVRGQWL
                     IAASMTCLLAALLLGTVVLPGVLAILFGLLIGTAGGSIRALEAAAFPRHFGTRHLGAIR
                     GMVTSVSVGSTAFGPLLFAGLYQATGSYTPALLVAVPIPLAVVVAALCIRPPNLEREHH
                     ERERSGSATG"
ORIGIN
        1 agaccaacgc cgaagcgaac gaggagatcg cgtcctggga cagcctcacc gaagcaggcc
       61 cccgccccgt caagcaccgt cgcgcggcgc cgtccagacg ttggacacta gcccatctga
      121 tcgaggaaac cgcccggcac gcgggacacg ccgatatcct gcgcgaactc atcgacgggt
      181 ccaccggacg ctgaccctgg ccgtcacttt cctgcatgcg aggggcccgt ctcttgctcg
      241 ccgtcgtgca ggagcagatc gacgaacgtc tccatcgcct cgttcgcggc agccgtctcg
      301 ccggtgatca ggacgtcgtg gagcaatccg cgcgcgaccc gacggatcac gcgccggtgt
      361 gtgcgccggg gcgcacgatc atgagaacga caacggccgc ccacagcagg ttgtagaagc
      421 cggcgtacat ggagagggtg cgtagccccc tctcggtggc ggatcgcatg agcgcatcgc
      481 gttgccgcgg gtagatctgc agcgccagca ggagacccgc ggcagcggtg agcaccatgg
      541 agacgatgat ccagatctcg cccatgcggc cctgcaggga ggccagcacc atacccacga
      601 cggggacgat gatggcgaca acgctgtagc cgcgggtgat gcggtgcagc gcgagggcca
      661 cggccaagct gcgctccccg gaggtcgtct gcgaggcgcc gggttgcgcc ggttccgtgg
      721 ccggaacggg agcggcgacc ggcgcgtagc gaggaaacag gcttgccgcg acggccgatc
      781 ccccgacgaa aacgatggcg gccagcacgt gtaccgacaa caacacatct tccatggctt
      841 ctccgctccc aagacacctt caggttgcct gaagcctagc gcaatgcttc aggcggattg
      901 aaggtgctcc ggtgtcggga agaccggcaa ccgcgccgac gggggtcagt tcgccgcgga
      961 ttcgccttcg aacgcagcac ggaccgcggc acccacctgc cgctggatcg ggtcggcatc
     1021 cgggccgaac atccggtcgt cgacctgcgc cacggcggcc cttgccgcat ccagcagctg
     1081 ggcgccctca ggggtcaccg cgatggtgga tgcggagccg gggcgggcgg tgttgtcgcg
     1141 gacgagtcct gcggccgcga gtgctttcac cgccgcgtgc acactttgca cggtggtgcc
     1201 ggacatccgg gcgagttcgc tgaacgacac cccgggcaag ccggagatat ggccgagcag
     1261 cccgagtttg ctgaccgtga gatcgagcgg cgcgagagtg gtgttgagct cgctctcgat
     1321 ccggcgcgcc aatgtcagga cgacaatgga ggtgctggtc accgggggag tggagctgtc
     1381 cttctcgtcg gtcatccgtt cagtgtctcc taccgtgctc cgtgtcgtgc cgatcgccga
     1441 tccgcggtga acgaggtgat cgcggagttg tcgccgagca gcacggtttg ctgtcgttgt
     1501 gcggccttcc ggtgacaaac cccccgccgt gcacgaggat cttcgttggc gggggatttc
     1561 ggccgggtcc ggctgggccg gcgtgcgcga aggagttcac tgtggagcag aacccgctcg
     1621 tcgaggtcgg cctgccggtc gcgctgttcc tcatcatgat cggcattggc ctgacgctca
     1681 cgtcgaagga cttcgccagg gaggccaggg acccgcgtgg ggtcatcgtc gggacgctcg
     1741 ggcagatcgt gctgatgccc gctctggcgt tcctgatcgc ctacctgttg tccttgcctg
     1801 ccgcgatcgc cgtcggtctc gtgatcatcg ccgcgtgccc tggcggtacg acgtcaaacc
     1861 tcatcgcgta cctggccagg ggcaacgtcg cgctgtcgat cgtgctgacg gtgctggcca
     1921 gcctgatcac cattgtgacc ctgccgatcg cggcgaatct cgcgctgcgg tggcagcccg
     1981 cggcctcgga cgtcgcgatc gaggtgcctg ttctgcgaac catcgccctg ctggtcgtca
     2041 tcgtgctggt cccggtcgcg ataggcatgg cgcttcgcgc caggtggccc gagcgtgccg
     2101 ccgcgctcga gcgggcggtg tcactcttcg gcggggtggt cctggcggtc ctcatcgtgg
     2161 cgatcgcgat ctcgctgggt gccgacatct ggacctatct ccggcaggcg ggcatcgccg
     2221 ccttgctgct caacctcggt gggctggccg tcggctacgg catcatgcga ctcgcccgtc
     2281 tttccttcga gagtcgactc gcgggcgcga tcgagctggg catcaagaac gccacactcg
     2341 gcattctcat tgccgtcaac gtgatcggat ccgaggccct ggcggtgccc gcggccgtct
     2401 acggcgtgct gatgtacgtc tccgcggtcg gcgtcgtggc ctacggccgc cgcaggggcc
     2461 ggcaggcctc cgcggtcggc gacacggttc ccaagccgtt gtaggtgccg cgtccctcgg
     2521 gggacgcctg ggtcaagtgg accaatacac cttgtgtata ctctcaaggt atagtgatca
     2581 tgagaggcgt catccgggaa ggggatcgct gaaagtcggg gacaggagcc ggtgcgtggc
     2641 ggagttcgcc gtgcgctcgg tgtgaaacag cgccgcaaat tctgccggcg cttgttccag
     2701 catttcatgg ccgacaacgt tgtcgatgtt ctccgtcctg ctctttcctt ttcgtgcgcc
     2761 tttggtgtgc cattttcagc cagggtttcg gagttcatat ctatgtcgta cgagttacgg
     2821 ttggcgcagg cgagatccgg ccgagccgcg acatgtctca ggtggacagg gtttgccggc
     2881 ctgttgctcc tcgtggtgat ggtatttgtt gccgccggaa ccgctggcag ggcgaactcc
     2941 ggaacagtat tcgactggct tggcggtctg cctttcgtca cgctcactgt cgcagtggcg
     3001 ggtatgggat tgttcatcct ggcgtggttg tttctcggcc ggttgacctg gccggacggt
     3061 cggcacacgg tcaccggtag atggttgcgg cggacgctgg cgctgtggag cgcaccgttg
     3121 atgttcgtgc cgcccctgtt cagcggggac gtgcacagct acctggccca gggagcgatc
     3181 gccgcgcgcg gtggtgaccc atatgcggtg ggaccggcca ccggcctcgg ggtcgacgcg
     3241 gagctgaccc gcaatgtcag ctcctactgg gtggacacac cgtcgcccta tggcccgctg
     3301 ttctcggctg tcgaacgcac gatcgcccag atttccgccg agaacgtatt caccgggatc
     3361 gcgctgcacc gggtactcga ggtcgccggc ctggtcgcga tcgtgtgggc cgtaccgcgg
     3421 ctcgctcgga gagcgggagt gcctgccgca cccgccctgt ggctcggcgt gctgaacccc
     3481 ctggtgctgt ggcatctggt tgccggaatc cacaacgatt cgctgatgct cgggctgatg
     3541 ctggtcggcg tggagctggc gctggccgct ttgagcggtg cccgcattgc ctggttgcca
     3601 ctgtgctcgg gcgtgggcgt catcgcgctc gccgccaacg tcaagctcgt cgcggtcatc
     3661 gcgctggcga cagtcggcgc cgaactggcc cgccggtggg gtgcgggcct caaacatctg
     3721 ctcgtctccg cggcggccat gaccgccgct ctggccctgg tcaccattgt cgtttcggca
     3781 ggcgcagggc tgggattcgg ctgggtgcgc actgtcagta cctcgaccca ggtcaacagt
     3841 tggctcgcgc cgaccaactg ggcgggcttc ctggtgggtg gtatcgggtc gtggttcgat
     3901 gtggacataa cgcagtcggc catcagcgtc ggcagactgg tgggcgcggt tcttgccgta
     3961 gttgcgatcg cggtgctgat ctggcggcag ctccgcggca ggacgggggc cctgcagacg
     4021 ctggcgttgg tgtcactggc gatcatcgtg ttcggccccg tggtccagcc ctggtacgtc
     4081 ctgtgggctt cggtgccgtt tgccgtctgc ctcggccgcg gaagggcacg agggatggtc
     4141 accggtgcga ccgcggtcct ggcccttgcg ctgccgccga tgggtggcga cttcggcggc
     4201 cgcatcggtg acctcgtact cgcatacgtc gtcgcgtccg ttgtcgtggc tggcgcggcg
     4261 tacgtgctcc agcggcggtt gttcccggct cggaccgtct tggcaaccga agccgaaccg
     4321 aagagcgcca gggaactgac gccctcggtc tgagctaccg ggtgatggcc gggccgaagg
     4381 tgagctcctc gctgtggcgg gcctcgccat ctggcagctc gccgaggtag aaccgagtcg
     4441 acatggtgcg ttcggtcagg tcgaataccg agcgccacag cgtccgcatc ggatacagca
     4501 tcgagttggc cgcggtgaag ccgatctcgt ccaaggtaga gcgcagtgcc gagcccgtcg
     4561 tcgcgggttc ggtggcccgc ttccgcagca tgcggtagcg ctcgtaggtc cgcagcgtct
     4621 cctcggtgtc ctcgggcagt gccgccgggt cgggatggcg gtgcagcagg tggttggtga
     4681 cgcagagggc gccactgtcg gactcgacga tgtgctcgtc gccgccgggc ccgtgttccc
     4741 agacgaacga gttgccttcc gcgtcggcga tcaggtagtg caacggcgtc ccgaggtcgt
     4801 actgtttcgc gccgagcagt gcacgcttgg cttcgtccgc ggtggcgcac gtctcgagga
     4861 cgaaccgagg tagctgtgtg ctggaaagtc cgacctgggg ttcgtcgacg acaggcgcgc
     4921 ccgctgtccc ggagtcggcg atgagcagcg ccaccgcgag cccgtactcg ttgatgccct
     4981 ccatgcaaca gtccagttcg ttcatggtca gcaccgtggt ggccgggcca tcgtcgggca
     5041 cggtggtgac gacatagggc cgcccggcca tgggcgggcc ggtgtcctcg accgttcgtc
     5101 ccgagagcat ggcgaacaac gcggacgcgc tggtggtgaa gaagtcgtag ttgcgaccga
     5161 gcaggccgtg cccgttctcc gtgacctgcg gcgggtagaa cgtcgatgag cacgcggaac
     5221 cttctggcgt cccggtcaac ccatccaggt aggcacttct gatgtcgatt cccagcgttt
     5281 cggcggctcc gagcattctg gcgtgatgct gcggccagtt gcgttcgaac cagtcgagcc
     5341 tcgccccggc ccgcagcgga tcggcgggtt gtggacgcca gccgtagccg gagcgtgctt
     5401 cctcggcgag aaagcggccg atgtcgatct gactgccgtg cgcagtcaat tgacggacgg
     5461 tcatgaagtc cgcctcgcca ccgcccgcga cgatgtcgtt gctggtgttc atttggcttc
     5521 tccttgagtg atcgaatatg cgtacaaagt acccatctgc cgaggaggcg cgcgagcttt
     5581 cgccgaataa ccgggggtta tccctacctg tgccctagtg cacgcgtttt gcgctctagt
     5641 acacttcgga catgaaaccc agtgtgccgc cctaccttcg gattgcggga gagatcggcg
     5701 atcgcatcgc ccgcggcgag ctgcgccccg gcgaccgggt cccgtcagcc aggttgatca
     5761 tgcgcgaatg gggcgtggca atggcgacgg cgagcaaggt gctcaccacg ttgcgccacg
     5821 atggccttgt cgaggtacgc cccggtgtcg gcaccgtcgt actcaccgcg gggcgcgcga
     5881 ctccggcggt gcgggtgccc acggagggaa cgctcaccac ggcgcgggtc gtagaggcag
     5941 gcatcgccgt ggctgacgcc gacggtctcg atgcgctgtc catgcggcag gtcgccgccg
     6001 acctcggagc cggggtcatg tcgctgtacc ggcacgtggc gaacaaggac gagctgatac
     6061 gacacatgat ccgtgccgtg ttcgctgaac gcgagcttcc cgcgcccgcc cctgaaggct
     6121 ggcgcgcgaa actggagttg gtgagccgcg tccagtggga gctctaccgg cggcatccat
     6181 ggctcgccgc gcaggtctcc atgacccggc cgatgctgct tccggaaatg atggcgcaca
     6241 ccgagtgggt cctggccgcg ctcgaagggc tcgggctgac ccgcctggag atgacgcgcg
     6301 aagcggtcgc gctgcccgcg ttcgtccggg gggtcgcgct gtctgtcgcg gacgagatcg
     6361 aggcggaacg gaacaccggg ctcaccagcc agcagtggtg gctgtcgctg cggcacgagg
     6421 tggaggcgtt gtacggccgc ttcccgcggt tggtcctgat ggaggacgac gtcgccaagg
     6481 acctcgacgc ggtgttcgcc cacgggctcg cccgccatct cgacggcctt ggtgtggcca
     6541 tccggcaccg gcggaaccgg tagcggctcc agtacgcatg cgattgacat gatcaagctt
     6601 cagttcggtt cacgcaaacc tatgttgacc gtaatcaaaa gtgcgcttag tgttccaggt
     6661 catacgagac ccagctgaca cttgccggtc ggggtcgccc ctgcgaggcc gctgctgacg
     6721 gtggcatcca cgcaggtcag cgcccttgga gcggacagaa gtaggagcca ccatgtgtta
     6781 cggattcgat ggtgatgcgg cactggggca ctcactcacc gagcgtggga tgagccgccg
     6841 aaccatgttg cgcggagcgc tgacgggggc ggtcggggcg ggcttgcttg ccgcgggcct
     6901 cggtggggcg ccggcgcatg ccgccggtcg agcgaccggc aggccgcgcg tgccaccagg
     6961 tctgatcagc atccagttgt ggaccttgcg cgacgccctc tggggttcgc ccggattcga
     7021 cggcaccctg cgcgccatcg ccgacctggg ctaccccaag gtcgagcagg ctctgggcta
     7081 cttcggtcgc acggcaggtg aactgcgcgc cttctacgac gacctcggga tctcggcgac
     7141 ctcgagccac gacggcatca gcgagaaccg gcaggcgctg gagaccaaga tcgacaacgc
     7201 cgccaccctc ggccagtcgt tcatggtcgt gccgtacctg aattccgcga aggccgacga
     7261 ctggcggcgc tgggccgagg agatgaaccg ggaaggggag gccgcacggg catccgggct
     7321 gcgctacgga tatcacaacc acgcccacga gttcaccacc gatctcggcg gtggcacgac
     7381 gccgtgggat gtgttgaccg ctgaactcga tccgtcactg gtgcacctgg agatcgacct
     7441 gtactgggtg gttcgcggcg ggatcgagaa cggagacgga gcagccgacc ccgagggctt
     7501 cgccatcgac gtcatccgct ccgcaccgca acgcgtgctg cagtaccacg tgaaggaccg
     7561 gcacgccgac accggcgaca tggccgacct cggcaccgga atgatcgact ttccgcgcat
     7621 cttccgggcc cactcggttc tcgagtacat cgtcgagaac gacacccccg acgtcagtcc
     7681 gctgcagagt gccgaagtgg gctaccgcta tctgcgcgga ctgcgctact gaacccggga
     7741 ccggtccaca tcggactcct tggcaatgat ccaacactcc ccacccaacc gaacagtgat
     7801 gagaggtagg tgaccatgcg ggcatcacgc atggtggcag tgctcgccgc ggcgggggcg
     7861 gccctcgccg tcgcacagcc ggcatcgacg gccgagccgc tgcggcctga cgattcggcg
     7921 tttcagaagg tgacactcaa cgacacaccc ggtgagccgg tggacctcgc ggtcgtaccc
     7981 gacggccggg tgctgcacac cacccgcgcc ggcgaactct ggttgaacga cccggacagc
     8041 ggcctgaaca cgctcgcggc ggagctggac gtatacagcc atgacgagga agggctgcag
     8101 agcgtcgccg tcgaccccgg cttcgacggc aagagcaacc gttgggtgta cctgtactac
     8161 gccccaccga tgaacacgcc gaccgacgat ccgtccacac cggacatcaa tgagggcgac
     8221 gcgccgacga ccggcacggc ggccgacttc gctccgttcg agggcattca gcggttgtcc
     8281 cggttccagc tggtcgggga caagctcgac ctgtcgaccg agcagcagat cctcgaggtc
     8341 aaggaggacc gcggcatctg ctgtcacgtg ggcggcgaca tcgtcttcga cggcgacggc
     8401 aacctgtacc tgtcgaccgg cgacgacacc aacccgttcg agtccgacgg ctacgttccc
     8461 ctcgacgagc gtgcgaaccg caaccccgcc ttcgatgccc agcgcacctc cgcgaacacg
     8521 aacgacctgc ggggcaaggt gctgcgcatc caggtgcaac aggacggctc ctactcgatc
     8581 ccggagggga acctcttcga gccgggcacc gcgggcaccc ggccggagat ctacctgatg
     8641 ggcctgcgca acccgttccg gatcgaggtc aaccaggaga ccggcgagct ctacgtcgcc
     8701 gactactcgc cggacgcggg gtcgcccgac ccggagcgtg ggccggcagg gcagggccgc
     8761 tggatcgcca cgagcgaggc cggtaactac ggctggccct actgcgtcaa gccggacatg
     8821 ccctatgtgg actacgactt cgccaccggc cagtcgggtg agccgttcaa ctgcgcggca
     8881 ccggtgaacg agtcaccgaa caacaccggt ctgacgcagc tgcccccggt cgagcagccg
     8941 gagatgtggt actcctacgg cgagtccgag cagttccctg aactcggtac cggcgggatc
     9001 ggcccgatgg ccgggcctgc gtacgacttc gaccgcgccg ccacccgagg acgagccccg
     9061 gtggcatggc ccgagtacta cgacggtgcg ccgctgttct acgagtggac ccgcgactac
     9121 atcaaggcat tccggcagaa cgacagcgga ggtgtcgcat ccatcgagga cgttgtccct
     9181 tcggtcgatg tgtcgggtgt gatcgacatg gagttcggtg ccaacggcgc gctctacgtg
     9241 ctcgagtacg gcaagggcta cttcgcggag aacccggacg cgcaactggc tcggattgac
     9301 tacatcggac cgaatggcaa ccacacgccg accccgaagg cgtcggccga cgtgaccaac
     9361 gggcaggccc cgttgaccgt ctcgttctcg agtgacggca cgcatgaccc agagggtgac
     9421 cggttgcggt acgaatggga cttcgactcc gacggcgacg tcgactcccg gagtagtaac
     9481 cccacgcaca cctatcggga gaacggcgtc tacacctcga gcctgaaggt gaccgatgtc
     9541 ggcggcaagc accgtggccg ctcggcctcg gccgaggtcg agatcgtggt cggcaacacg
     9601 gcgcccgtgg tggagttcgt caagccggtc gacgggcagg ccttcgaatt cggtgacgtg
     9661 atcgagttcg aggtgagtgt gaccgacgat cagacggtcg actgctcgca ggttcaggtg
     9721 acctacatcc tgggccacga cgaccacggt catccgcaga cgacggcctc cggttgcacc
     9781 gggaccatcc agaccacgat cccgggaggc cacgacccgg aacacgacga gctgcgtggt
     9841 gttttccacg cgacctacac cgatccgggt gccgacggcg tgcccgcgct gtccggtgac
     9901 gccgagatcg ttctgcagcc acacggctga gagctgaccc ggcccgcccg tggtaccccg
     9961 tctgtcgcgg ggtgccacgg gcggtcggct ttgcgccggt ctagccgtgc aggagtgcgc
    10021 tccggccggg agggcggaac gcggaggtgc ccagccccgt cgggtggaac gaaaacttct
    10081 ctcgcggtcc ggtggccgcg ccgccgcgga ggtcttcctc cttgtaccgc acacaggtcc
    10141 gatgccactc catgattccc gccatccagt ccttgaggtc atcgacgtgc cgggtgaggg
    10201 cgccgcgcac ctgcacatcg aggtcgtact cgtcgaacat cgcgggcagg ccgtgtttga
    10261 cgaggtgttc gaactcccgc atccgctcgg ccatcaggcc ggcgacgacg tcgcgggcgg
    10321 cgaggcggtc gacgttgagg aagttctcca cgacgaggac catgttgtgc acctcgccct
    10381 cgaactcgat ctccttctgg taggagaaca ggtcattggt gaagcaggcg tagtcctggg
    10441 ccgcggtgtc cagctcgtgc atcacccgcg tccggtagag ctcggcaggt atcggctcgt
    10501 tggcggatag tctggcgagg ctcatcgtca tatcggaacc gaacgtcctg cggcgcatct
    10561 ccacgtagtc gatcgggtcg ggaatccggt tgtgcgcctg gttttccagc tcccacagcc
    10621 agctcgaggt catgtcctcg acagcggtgc ggaactccgt cctcgcggcc agcgacatcg
    10681 gccctgccgt ccgctgccac agatcggcca gtccccgttc gagcgcgttc accggttccg
    10741 gcgtttcccc tgcgtccagc ggcatgaacg cggcgaaccg ttcctggcac aacttcgctc
    10801 cggacaggtt tctagaactt ccgaacaccg cgggaaagta gtcgtcgccg taggtgcccc
    10861 aggccagcca gtcggaggag agctcgagct gcacctgact cgcgtcagcg tggatcatcg
    10921 ccgcgcagtg cgcgagatcg aacccggtga acttctcctc gtcccagacg gcgccgaact
    10981 cggttcccgg caccggggcg aacataccgg cccattccgc ccagccgacg gcgtatttac
    11041 gcgccgcgtc cagatgtgga ctggtgcgga ccgggtacgg caggtagaag tccggcaacg
    11101 gcaggtgacc gaccggtgtg aacggccggt gtgcgtgtcg cgggccgcga tggcggagtc
    11161 cctgagtgaa gagcgaagcg gcggccgtgc ccagaccggt cggcccgccg agcgggttcg
    11221 gcgcgatcga agccgcttcc tcgttcatgt accggctgga cctggcatgc cactcgtgcc
    11281 cacccgactg ccagtcctgc aggcccttga cataggccgc gacgccgccc tgctcgtggg
    11341 gtgggatcgc gtgctcggca agcagcgcgg gaacctcgcc gagcgcggtg ttctcgaact
    11401 gctgcagcct ggacgtcagc aggtcgttca ccagttccgc ggcctgctgc gtcgagcagt
    11461 cgaggaagcg ttcgaacacc agcaccgcgt tggagttctc gccctcctcc tgcacctcgc
    11521 gctggtagga gaacaggtcg ttgcgcaggt gcacggcgtc ggcgaaggtg tcggaaagga
    11581 cgcgcatcgg ccgggtcgcg gctatcctgt cgggaatctc ggcgccgacg gcgtactcca
    11641 ccaggttcgc cgaccatggc gcaccaccga ctcgcctgcg catctgcatg tactcgatgg
    11701 gattggcgat ccgtccgcga tcgatgttgt ccagctccca catggactcg atcatcaggt
    11761 tgtgagtggt cgtcgtgaac cgccttcgcc agccttcgga catcgatggg accgtgcgct
    11821 cccacagatc ccgcagcccg gcttcggccg gattttccgg ctcgggcggc gtttcccccg
    11881 gcgcggacat gaatcgctcc aggcggtcga ggtactcctt cgcaccggcc agatcacggg
    11941 agtacttgaa ctgctcgagg aaatggtcgt cgaagaagaa gacccacacg taccagtcgg
    12001 tgatcagatc cagcgcgagg ctgtcgcagt ccggatgggt gtacccgcac atcagggcgt
    12061 aatccatctg tgccagcttt tcctcgtccc agacgaggcc gccgctgggc ttcggcgcgt
    12121 ccagcatgcc catgcgcttc gcccactgcg tgctgtgctc gcgggcacgc tcgaggttcg
    12181 ggttcatcct cgccgggtgc ggtgtgtaga actcgggcaa cgtgaaggac tgcatggccg
    12241 gaatccattc tctgtgtctt ttcgaaaggc gctgcgctcg cggaaacggc gtctctcacc
    12301 tgcaccaccc tcactgcctt gccgagggtg gcaacgtgaa gcggatcgtt tcgtgtgcgg
    12361 tctcccgttg tgcgacgctg actgggccga gagcgccgag cgcttcgatg acggcgtcga
    12421 cgagtcgtgg tggagcagag gcgcccgcgg tcagaccgac gacaccgacg ccgtccagcc
    12481 actccgggcg cagctcgccg acgtcttcga tacgtgccgc ggcggttccg caccgctggg
    12541 cgagttccac gagccgcacg gaattcgacg agttcgccga gccgaccacg agcaccagat
    12601 cggcctcctc ggcgatcgcc cgcagcgcgt cctgccgatt ggtggtggca tagcagatgt
    12661 cctcggaggc tggaccgcgc agctgcggga accgcttgcg cagggcggcg atcacctcga
    12721 cggtctcgtc caccgcgagt gtggtctggg tcaggtacga gaccctgctc gggtcgggta
    12781 cgtccagagt ggccacctcg tccgcggtct gcacgaggac cgtgtgttcc ggtgcctcgc
    12841 cgaaggtccc ctcgacctcc tcgtgccctt cgtgtccgat caggatcacc gtgtcacccc
    12901 ggccggcgaa tcggcgggcc tcggcgtgca ccttggtaac cagtgggcac gtggcgtcga
    12961 ccacctcgag gccgcgttcg gcggcggtgt cgcggaccgc cggcgagacg ccgtgcgccg
    13021 agaacaccag cgtcgaaccg gaaggcactt cgtccaggtc gtccacgaac acggcgccgc
    13081 gagcctccag ttcaccgacg acgtgggtgt tgtgcacgat ctgcttgcgc acgtggatcg
    13141 gcgcaccacg acggcgtagc agttcgtcga cgatgtcaat ggctcgttcg accccggcgc
    13201 agaaggaacg cggagacgcg agcaggatcg tgcgtggacc ggccacggct cgccacgccg
    13261 gatcctggac gtcgatgtgc accctcgctt cgtgccctgg catgtggctc cttcgtcgac
    13321 gggccccgat tgccggggcg tgcgttcagt ggtcccgacg ggtgagcagc ccggccagcg
    13381 tggccagctc ggcagccgcc cgcggctcgg gtcgcgccgc acggaggtgg ccgagtgccc
    13441 tgcggagaag gtcgtccgcg ctggcctgac tccagtcccg cgcccctgcc tcgtcgatca
    13501 gtgcggcggc gcggcgcaga tccgcctcgc tgagcggccg ctctcccgcg tacagcgcgg
    13561 ccagcgcgcg tcccggctca gccgaaccac cctgctttgt cgacccgcag agggtggcca
    13621 cgaccggcag cgtcttcttc cggctcttca ggtcggagta caccggcttg cccgtcgcgg
    13681 cagggtcgcc ccagataccg agcaggtcat cgacgaactg gaatgcgagg ccgagatgct
    13741 cgccgaagcc gcgaagctgg cgcacctgct ccaagctgcc gtcggcggct accgcaccga
    13801 gggcggcggc gcagcccatc agcgcgccgg tcttgccctc cgccatccgc ctgcactcgt
    13861 ccagcgagac ctcttcgcgc cgctcgaagg caaggtcttc cgcctggcca cggacgagtt
    13921 cctggaccgc ggcggcgaga atccgcatgc tcctggcagc cgggccgccc gctgcggcga
    13981 gcacgtcgag cgcgagcgtg agcagtgcgt ctccggtcag gatggccggc gccgtaccga
    14041 agactgccca cgcggtgggg cggtgccgcc gggtgacgtc gccgtccatc acgtcgtcgt
    14101 gcagcaggga gaagttgtgt gccagttcca cggcgacagc ggagggcaca gcggcttgcg
    14161 gggtgccgcc gacagcttcg gccgcgagca gtgccagcgc cggtcgtacc gccttgcccg
    14221 tggcggcctc ggtggccttg ccgtgctcat ccagccaacc gaggtggtag gcggcgatgt
    14281 ccctgactgg ccggggcaat gtgtcgaccg cggcgcgtaa cgcggggcgg accgtgtcct
    14341 gactccagcg cagcaggtcc gcgggcggac gtgcccccac tgcatcatcc gtggcctgtt
    14401 ctgtgccggg cacgttcgtc atgttcgtgg cggacatctg ttcaccggcc gatctcgacg
    14461 ttctcgagga tgcccagtgc gtccggaacc aggacagcgg ccgagtggta ggtgctcacc
    14521 aggtaggaca tgacggcctt gtcgtcgacg cccatgaacc ggacgttcag acccggctcg
    14581 tactcgtccg gcaggcccgt ctgacgtagg ccgacgacgc cgtggtggtc ttctcccgta
    14641 cgcatggcga ggatggcact ggtgttgtgc tcgctgaccg ggatcttgtc acacgggaga
    14701 atcgggaccc cgcgccagct cgtcacctgg tgtcccttga gctccatact cgacggatag
    14761 aggccgcggc tgttgcactc cctgccgaaa gccgcgatcg tgcgagggtg cgcgagcatc
    14821 aactcggtct tgcgccgccg ggacaacaac tcgtccaggt cgtcggggct gggcggcccg
    14881 ttgcgggtgt ggattcgctg cttgaggtcg gcgttgtgga ggaggccgaa gtcggggttg
    14941 ttgacgagtt cgtgttcttg gcgttcgcgg agtgcttcga tggtgaggcg tagctggtgt
    15001 tcgagttggt tcatgggttg gttgtagagg tcggcgacgc gggtgtggac tcggagcacg
    15061 gtttgggcga cgctgagttc gtattcgcgg ggtcggactt cgtagtccac aaaggtggct
    15121 ggtaggtcgg cttcgccttc gtgtcccgag gcgatgtcga cctcggcctc gccataggcg
    15181 ttctgcgacg cggaagtctg cctgcgctgt tcgtccagat gcctgcgcaa cggttcgctg
    15241 cgctggacga ctgcctcgaa ctccgcgagt ggcagcgcga gcacggtgca cggagtgatg
    15301 gtcttgacac tgaactccca gatgctctgc gaatccagta gtgtctcgtc cccgaaatga
    15361 tcgccgtcgg caagtgtgcc cagcaccgtg gggtcaccgt agctgccggt gccgagcttg
    15421 ttgaccttcc cgtgggcgat caagtagacg tggtcacgct ggtgtccgaa ctcgacgatc
    15481 acctcgccgg ctcccaactc ctgttgttcg aaccggccgg ccagttcggc cagggtcgga
    15541 tcgtcggtga acccccgtag cggagggagt tcgcccagtt ccgccgggat cacctgaacg
    15601 gccgtaccga tgttcgtgaa cgtgacccgg ccgtcgccca ccgcatagct gagccgccgg
    15661 ttgacccgat aggtgccacc cgcggtctcc acccacggca gcattcgcag cagccagcgc
    15721 gaggtgattc cctgcatctg cggcacggac ttcgtcgtgg tggccagatt cctggcggcg
    15781 gcggtgccga ggctcgacaa cgccctttgc ccggtggttt cgatcggttc ggtagcggtc
    15841 atggctcaac tcaccagttc ctgttcgtgg ctcttgtgtt cgaagggggt agcgaaggac
    15901 aggcggactc aggactcccg cccgatctcg acgttctcca gcacggccag cgcgtccggc
    15961 accaggacgg ccgccgagtg gtaggtgctc accaggtagg acatgatggc ctgttcgttg
    16021 atgcccatga accggacgtt cagccccggt tcgtactcgt cctgcaagcc ggtccggtgc
    16081 agtccgatca cgccctggtt cgcctcgccg gtacgcagca gcatgatcga gctggtgcgg
    16141 gtgccggtga ccggaatctt gttgcacggc aggatcggaa ctccgcgcca ggacggcacc
    16201 tgatgcccgc cgtagtcggt gttcatcggg tagacgccga cccggttgca ctccctgccg
    16261 atcgccgcga tggtcctcgg gtgcgccagg aacaccgccg gctccttcca aaccatcgcg
    16321 agcagggcgt ccagatcgtc cggtgtcggc gggccgctac gggtctgcag acgctgcttg
    16381 aggtcggcgt tgtggaggag gccgaagtcg gggttgttga cgagttcgtg ttcttggcgt
    16441 tcgcggagtg cttcgatggt gaggcgtagc tggtgttcga gttggttcat gggttggttg
    16501 tagaggtcgg cgacgcgggt gtggactcgg agcacggttt gggcgacgct gagttcgtat
    16561 tcgcggggtc ggacttcgta gtccacaaag gtggctggta ggtcggcttc gccttcgtgt
    16621 cccgaggcga tgtcgacctc ggcctcgcca taggcgttct gcgacgcgga cggcgcggat
    16681 gctgctctgt ctatgtgcgc acgcagtgcc gcgccacgct cgtccagtcc ttccagtgcc
    16741 tgccgctcca gtgccagcat tgtgcaggag gtgaccgcct tgatcgtgca gtcccaatca
    16801 cccggcgatc gggtcagcgc ccggccgccg aagtagtccc catctgcgag tgtcctgagg
    16861 acggtgtggt caccgtatgc gccggctccg agctggttca ctttgccgtg tgccagcagg
    16921 aacacctcgt cgaccggctg gccctggacg gccagcaggt cgcctggttg gtactcccgc
    16981 tggacgaacc gaccggccag ctcgcgcagt acttcctcgt catcgaagcc gcgcagcaag
    17041 gggagctcgc gcagttcctg ggggatcacc ctgatcactg cgccgtcgct gctgaaggtc
    17101 accctgccgt cgcccacggc gtatcgcagt ctgcgattca ctcggtacgc accgccggga
    17161 acctccaccc acgacagcgc acgcagcagc cagcgtgagg tgatgccctg catctgcggg
    17221 accgttttgg tcgttgtcgc caggttgcgt gcggcagtcg tggccaggct cgacggccgg
    17281 cgttcctcgt cgtcgatacc ggcgctgccg ctcggtcctg ccgagtccgt cacagtcaca
    17341 atgccaacca ccattctgat cgcagaattg tccgaggact gagagttgtc gagagcgccg
    17401 cctgccgaag gtggacgtct tgatcggcga cgcggccgtg aaccgaacat agcaaaactc
    17461 cagacacgca caaggacctg aaaaatgtgt cactcgacaa gagcaatgct ggagccacgg
    17521 gggagcttcc ggaataaaaa tggatcatgg aatgtcacat ccagccacat cgtccgactt
    17581 ggatggacgc atcgacgacc ctaaaggatt ccgtctaata cgaccgagaa cactaatttt
    17641 cggctgcatt caaacgatct ttaggccaag tcggtgacat gatctacccg gaccgaatcg
    17701 atcgaatgaa gcgttgtggc tacctcttgt gacacgggtg cacgtgtggc tagctggaga
    17761 gggccgagtc gatcgaccgc cgttcggtac ttggggcagt tctgtatctg ttgttactta
    17821 gacgcttttc ggaggtacgt caatttgcga tgaacatata tctcagtggt gttatatggg
    17881 tggtcggcgc atcggcggtt gccggtgtca gtgcttatgt ggttcgtcgt ttcggtcagg
    17941 acgagggcag gccgggcaac aacgacgcgg ccggacaggt gttcaccatt gtcgccggcc
    18001 tgcacgctgt gctggtcgcg ttcgtgctga tcgcgcagtt cgacgccgtc acccaggccc
    18061 gcaaaggttc ttacaccgag gcgcaggccc ttgtcgccgc ggcctggagt gccgactcac
    18121 tgccggagcc cacccgcagc caggtacggg cccacagcgc ggactacgcc agcaccgtgc
    18181 tggacgagga atggccgcag atgcgcgccg acaccgaagt gagtcggtcg ggatgggaac
    18241 agctcgaccg gatccaggtc gacctggcga aggcgaaggc cgacgagaac tggcaggagg
    18301 agcgaaagac ccgggccacc gaagcattga ccgtggtggc cgaggcccgt cagcagcggg
    18361 tgcagcaggc caacggtgat caggtcggcg ccgtggtgtg gttcgcgctg atcctcggca
    18421 gtgtcatctc aacgctgttg cccaacctgt tcggaggtac ccggctgggt acgcatgtca
    18481 tcatcgtgtc cacattggcc ggtaccatca ccttgctgct gttcgcgatc taccagctgc
    18541 agaatccctt cagcggtggc gcggtggtgg agccggacgc gttcagaaac gcgctcgagc
    18601 ggctgcgctg agcgccatgt cgccggatgc gcttccaggc ggacgaggct cggcggtcct
    18661 gctggtcacc atcctgctcg tcctgtttgc ggcgccgcag ggacttgccg agtattcccc
    18721 cgcacagcct gctgcggact gcaccgtgat gatggtgcgt agcgacagcg ggagtggcgt
    18781 ctcgacgatc agccgggtgg acctgccatc ggccaccgtc accgaactcc cggcactgcc
    18841 acagcaggtc gacgcactgg gatacgcgca gtcgcagtca ctgacatacg gcgtcgctcg
    18901 atcgggttcc gcggtgacga tcgatcgcga cggcaagctg atcgatctcg gcgccatccg
    18961 gttcggcgac ccgcccgtac ggtggaaagg tctcggtgga gccagcgcgg gcacggtggt
    19021 cggtgaccgc tggtacatcc gcaagagcgg ctttctctac attgtggaca tcgaacgccg
    19081 tagtccaacc tacctcaaca ttcttcgcgc gaccgcgctc gctccgcccg acctgtccgc
    19141 gctcggagac ttcgatgccc acccccacga gggcgtcctc cacggcgtgt cggtatcggg
    19201 taagggcgac gtgacggccg tccggatcga catcggcacc ggccgcatca cgccgaatcg
    19261 ggacgttcaa ctgccgggag cggacgcatt cggttcggtc gtcttcggac cggacgggtc
    19321 cggttacctg ctcgcggacc ggtcctccgg acaaaggcag cctgtaccgg ctttcccccg
    19381 gcggccccgg tgtgatcacc gagatcgcgg cggtaccgtc gtcgtcgatc tcggacatgg
    19441 ccgggtgcct gggaccacgt ccacctgagc ccccctcgcc gacagcacca ccgtccccgc
    19501 cgactgcacc accgccgcca gcggcgccga cgtccgaacc ggaacctgaa ccggtgccac
    19561 cggacccgac gtcggcgccg gaaccaccct ccgcggtgcc gacgccggag agcgcgcccg
    19621 cgacctcagc cacgtccttc gcgccaccga tgaaacggcc gcctgcctgg tcgaacgagc
    19681 aggagccgta cgcggcggct gacaacggca gcacggagaa gaagcggcgg tgggggctga
    19741 cagtgctgtt gctcgtggtc ggcggggcgg ccgtcgtccg ggcagcgggc cggacgagat
    19801 gagcgaatct cgaatatgac acagggaatc gaggaggtcc gatgtcgatc cgccggagac
    19861 gaccgaagtg gtgtgtgttg ctcctggtcg tgctcgtcgt gtccttgggt gtggcgtggc
    19921 ctgcggttgc cgacgacggg ccgcccggag ttcatccgtc ggctgtcgac ctgaccctcg
    19981 cccctggtga gtcgcgcgag gtcggcaagc ggatcaccac ctcctccatt ccgtcgaacc
    20041 cggacctgca cttccttgct gacaccacca gcagcatggg tgcggcgatc gccggtgtcc
    20101 ggcagagtgc cggaaccatc atggacaccg tccgccgtgc gcagccgagc gctcgattcg
    20161 gcgtcgccga gtaccgcgat gtgcacgctg atctggtgtc gtaccgggtg aaccagacgt
    20221 tgaccgctga tcccgggaag gtccgggcgg gtatcgacca atgggttgcc cagggtggtg
    20281 gtgacgcgcc ggaggacgcg atcaacgcgc tgtaccggct tgccgtggac agccgcgcgg
    20341 tccggacgga caccacaagg atcgtcgcgt ggttcggcga cgcaccctca cacgacccca
    20401 gcggcggcca ttccttgcaa gagacggttg ccgccttaca ggaggcgaac atccgtgtcg
    20461 tcgcggtgga ctccgcaggt ctcgatgcgc atggtcaggc atcagccgtc acatcgggca
    20521 ccggaggtgt gctgcttcgc ggagtcgcgc cggacgcgat tgccgacgcg atcctgcggg
    20581 gcatcgcggc cgtcgaggtc accgtggcgc cccacgtgac cgactgcgcc cccgagttgt
    20641 cggtactcaa ctcacccgag gcgcttgtcg tgccgagtgg gagcgtcgct cggttcacgg
    20701 agaagatcac cgtcgcgcca gacgccgctc ccggcacata tcggtgcacc gtggactacc
    20761 tggtggacgg ggtgtcgcgc ggatacgtcg agcggaacac cgtgcacgta cccggacttc
    20821 gcatcgacga ctcgaccgtg cgcgagggcg cggcaggcac cgccccggca acgttcacgg
    20881 tgacgctcgc cccgccgggc ggccggcccg tgacggtgga ctacgaaacg gctgatgcca
    20941 cggcgaccac gccggacgac tacgcgaaaa ccagcggctc gctcactttc gagccggggg
    21001 agacgacgaa gaccgtagtc gtcggagtgc acggcgatct tgtggacgag aagaacgaga
    21061 agttcacggt gcggctctcc gccgcgagcg gtgcggggat ggtcgacccc gaaggagtcg
    21121 gaaccatcac cgacgacgat cgcgacggca cgttcggatg caccggcacg tcggccgagc
    21181 tcgccgggat cgcaccggtc cgggcgaacc cggcgggcta cccgtgtcgg gacgacgact
    21241 ccgccatgcc cggcggcgac ctccgcgccg gtggaatcgt cgtgcgtgcg cgcgaactga
    21301 ccgccacggc caaccggacc ccggatgatc tcgcggtacc acccggcgcg ggtgacactg
    21361 ccctcggcac cgccggtctg tccagcgcga cggtgaccgc tccgggcctg acaatcgagt
    21421 tcggcgtgat ccgcgcagag gcatcggtaa cctgtgttgc cgatgccggc gggttgaagc
    21481 cggagttggc gagcacctcg aacatcgcga gattgtcgat caacggggtg ccggtggacg
    21541 ttggctcggt cccctcgacg atcccgctgg cgatcggtgc gctcactcta aacgacacga
    21601 gcaccgacgg aacgacggtt cggcagcgcg cggtcaccct caccaccaag gacgcggttc
    21661 tcgttctcgc ggaggccggc gcaggtacaa ccagtagctc gttgcatccg gacggcagtg
    21721 cctgccggag tctggagcat ttccgacgga tgcgttgatt ccgatactcg gttacgaaca
    21781 cgctgatggc gaacgcgagt ggaagcgttt tcatgcttga tgacgtcgcg gagtcgccgc
    21841 gggcggccca agaggcgctg gagaccagcg gagccggtgc cgttcgtgct gtgttagtcg
    21901 tccggctttg ccgactccca cgagcgggcc gctgccgtct ggaacgagca cctcgtcgat
    21961 gagtcggtgt gaagacaacg cagctggagg aaaccgacat ttaggccgcg gtgggcgggg
    22021 tacccggtca gtggctcatg gccggagtca cctgaaagga gggccgatga ccgccaccga
    22081 acgcgtcacc ggaacacggg acgagcattt cgacctcacc agcgtcctgt accacacgtt
    22141 gcaggaggcc gaaacgctgc agcagtacat caacgacgcc aggcaggccg gtgacgaaga
    22201 ggcagccgaa ctcttccagg agttgcggga ccacgatcag cactgcgccg gacaagtgaa
    22261 gaaactgctc gcccaacggt tccagcaggc gagctcgtag ttcctgctcg acgggccctg
    22321 gtgaccggta gcgccggggc ccggagagtg ggcacacccc atcgcgtcaa ccagagtgtc
    22381 tgaagtggat ggttgtgctg gttctgccac gtgtcctgac aacgttgtcg tccgctttcc
    22441 ctgggagtca ctctgattac gtccgctcgt ttccgctcac gttcgctttc tccgtcggga
    22501 ttctacggct ggcacatggt cggctggtcc gcgttgatgg tcgcggcaac ggcgccgggc
    22561 cagaccgcag ccgtctcggt gttcatcgat ccgatgatcg ccgaactggg agtgagccgc
    22621 tcggcgatct ccaccgccta tctgatcggg acgctgaccg gggcggtggc gatgccgttc
    22681 gtgggcagga tgctcgaccg tttcggcgtg cggcgggtga tggccgggat cgggatcgtg
    22741 ttctcggcgg ccctgtgctc cctggccgcg gtgagttcga tcgtgggact cacagcgggc
    22801 ttcgtggtga tcaggatggc cggacagggt gcgctgggcc tcgcggccac caccgccgtc
    22861 gcgttgtggt tcgaccggcg gcgcggcacc gctgtcggga tcgtcagcgc tgtgggcgcg
    22921 tcggcgatct cgctggcgcc ggtgctgctg gagagccttg tcgcggactg gggctggcga
    22981 cggacgtggt tggccgaggg catcgccatc gcggtgctgg ttgtgccggt tgctctgctg
    23041 gcgatgcgca atcgccccgc tgacctcgga caacagcccg acggcaaagc cgccgaccag
    23101 accacgccgc cgagggcgat ctggggtgtc acgcgtgcgg tcgccctgcg cacaccgttc
    23161 ttctgggtgg tcaccgccgg gatcgccgcg accggactgc tgtccaccgc gatcaacttc
    23221 caccagatca gcctgctcac cgcccgtggt ctgagcaccg tggaagccgc cgcgaacttc
    23281 ctgccacaga ccgtcgccaa cctgctgggg acactgctga cggggatgct ggccgaccgc
    23341 gtgcgcggtc agtggctcat cgcggcgtcg atgacatgcc tgctggccgc gttgctgctc
    23401 gggaccgtgg tgttgcccgg cgtgcttgcg atcctgttcg gcctgctcat cggcaccgcg
    23461 ggtggcagta tccgagcgct ggaggcggcg gccttcccgc gccatttcgg cactcgtcac
    23521 ctcggtgcga ttcgcggcat ggtcacgtcg gtgagcgtgg gctcgacggc cttcggtccg
    23581 ctgctgttcg ccggcctgta tcaagccacc ggcagctaca cgcccgcact tttggtcgcc
    23641 gtcccgattc cgctcgccgt cgtggtcgcc gcgctgtgca tccggccgcc gaacctggag
    23701 cgcgagcacc acgaacgcga gcggtccgga tcggcgacgg gatagctcgg ggacggtagg
    23761 gctcgctcag cctcccgatg gttcgaggtc gacgtcgagc agggtcgcga acagcttctc
    23821 caggtggagt tgccacgcgt cgccgatcgc ctcggtgtcc gcagccagtg cgggtggacc
    23881 ggtctgggtc acttcgacgt aggtggccag ttccgggtcg tgcacgagcc gccagcgaac
    23941 cacccccgcg ggcgcgcctt cgggtgacca ccggtaggtc agctcgcggg gcgcgtccac
    24001 ctcggtgacc gagccgggga gcgcgggggc cacggtgaag ccatccggcg gagcctggcc
    24061 gggatcgacc tgctttcctt cggtcagtgc cgcccacacc gtttcgaacg ggcgccacac
    24121 cacgtcgagt acgcaacgca cctggaagcc agtgtcggtt tcggacaccg aggctccggc
    24181 aagattccac ttccgcaggt agtgcagcat gatcggccgg tggtcgaccg tctcggcctc
    24241 gcggccctcg agccgggcaa ccatcgcggc gagacagatg tcccagcccg tggctgtgcg
    24301 ccccgcggtg aaccccgagc ccgcgccgag tacctgggtg aacacgagca cgcagcccct
    24361 gtcgtcgggc aggatctcga accgcagcac gtcgctgttc cagcggaacg cgtacacctt
    24421 cggcgggtcg aactcca
//
