LOCUS       NZ_FOET01000021        27552 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces radiopugnans strain CGMCC 4.3519, whole genome shotgun
            sequence.
ACCESSION   NZ_FOET01000021
VERSION     NZ_FOET01000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces radiopugnans
  ORGANISM  Streptomyces radiopugnans
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900110735.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:56:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,515
            CDSs (total)                      :: 5,440
            Genes (coding)                    :: 5,315
            CDSs (with protein)               :: 5,315
            Genes (RNA)                       :: 75
            rRNAs                             :: 4, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 4, 5 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 41 of 125
            Pseudo Genes (incomplete)         :: 106 of 125
            Pseudo Genes (internal stop)      :: 6 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:58:30
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 41437
            Orig. end                         :: 68989
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOET01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27552
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..27552
                     /SMILES="NC(CS)C(=O)NC(C(C)S)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27552
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:25559](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..25559)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    816..829
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(819..2678)
                     /locus_tag="BMY40_RS25690"
                     /old_locus_tag="SAMN05216481_12139"
     CDS             complement(819..2678)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157642.1"
                     /locus_tag="BMY40_RS25690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12139"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_093663176.1"
                     /transl_table=11
                     /translation="MRIRDLPYPDPGEPDVRSGFRLMLWLWRSQLGGQLKALAWGTLHM
                     AAVASFPLAVGMAVQAATERSGDRLVLAGALTVALGLAVTVGDTMLHRAAVTNWITAAA
                     RVQQLLARRTAELGAALTRRVAAGEVVAVSTGDIEKIGWFVEAVSRFGAASLTTAGVCT
                     ALVVYEPLLGVVVTLGVLVLVSAVLPLLPPATRRADAQRAKAGRATELAADTVAGLRVL
                     RGIGGEELFLDRYRRASQEVRRAAVRTARMWSLIDAVQVVLPGLLLIAVVWLGTRLALD
                     GRVAVGELVTVYGAVTFLLFPLRLFQEIAMAYSFSRPSAERAARVLGLRRLTRAGAARA
                     GGDARLPHGDLYDPVSGLLAPAGDLTAVVCGDPDAAGRLAERLGGHGTGSGTDGPSVLL
                     GGVALDDVPLEAARTAVLVQDKDPVLLSGTLGELLDVPSSGAVAPGRALEAAQCGDVLA
                     ALVRAGGAPDGDPMRARITERGRSLSGGQRQRLALARSLVADPQVLVLDEPTSAVDSHT
                     EARVAGALRRLRAGRTTVVFSSSPLLLDRADRVVFVSGGEVTAVGTHRELLADEPGYRA
                     VVAREAGGDDDNGTDGTAGTGRATAGTAGVREPRRHEQMEENA"
     gene            2794..3555
                     /locus_tag="BMY40_RS25695"
                     /old_locus_tag="SAMN05216481_12140"
     CDS             2794..3555
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018842976.1"
                     /locus_tag="BMY40_RS25695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12140"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_093663200.1"
                     /transl_table=11
                     /translation="MSRPGTRFGLGARRRASAVCAAATALLLLAGCGGGGAAGADPSSR
                     PRQEASQPPSPSGAGARRIPGVGERLHAEIPESARQVVAVHGAGKDSEDATVALYTRRG
                     ETWTRERRWPAHNGKRGWTPDHREDDKRSPVGVFTLSDAGGVLPDPGAKLPYTRSAAFA
                     APRHWPERYRHDFDYVIAIDYNRVRGTPPNDPTRPLGREKGGGIWLHMDHGSGTSGCVS
                     LSRAAMEYLLRTLDPAQHPVIVMGDRQSLAS"
     gene            3782..5692
                     /locus_tag="BMY40_RS25700"
                     /old_locus_tag="SAMN05216481_12141"
     CDS             3782..5692
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088575.1"
                     /locus_tag="BMY40_RS25700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12141"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_093663177.1"
                     /transl_table=11
                     /translation="MHRDEPDWTPPQRRKGEPQPPAQIRRILRLFRPYRRRLAVVGLLV
                     GASSLVSVASPFLLREILDVAIPEQRTGLLSLLALGMIATAVLTSVFNVLQTLISTTVG
                     QHVMHDLRTGVYAKLQRMPLAFFTRTRTGEVQSRIANDIGGMQATVTSTATSLVSNLTS
                     VVATIVAMLVLDWRLTLVSLLLMPLFVWISRRVGRERKKIATRRQKQMAAMSAMVTESL
                     SVSGILLGRTMGRADSLTRSFAEESERLADLEIRSNMAGRWRMSVIGIIMAAIPALLYW
                     AAGLLLHLGGPAFSIGTLVAFVTLQQGLLRPTVSLLSTGVQVQTSLALFQRIFEYLDLP
                     VDITEPARPVRLERARGEVRFENVGFSYDPGSATPTLSGIDLTVPAGSSLAVVGATGSG
                     KSTLSYLVPRLYDVTGGRVTIDGIDVRELDFDTLARTVGVVSQETYLFHASVADNLRFA
                     RPGATDAEIEAAARAAQIHDHIASLPEGYDTLVGERGYRFSGGEKQRLALARTILRDPP
                     VLILDEATSALDTRTEQAVQRAVDALATGRTTLTIAHRLSTIRGADQIVVLEGGRIAER
                     GTHDELVARDGRYAALLRRDAVLPESAGPESAGPQQAGPEQAGPVGPAGSGPGAVETAP
                     A"
     gene            complement(5700..6188)
                     /locus_tag="BMY40_RS25705"
                     /old_locus_tag="SAMN05216481_12142"
     CDS             complement(5700..6188)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481989.1"
                     /locus_tag="BMY40_RS25705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12142"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_218158321.1"
                     /transl_table=11
                     /translation="MTAPAVELRETAPGDLPSLFRIQLDPEANRMAAFTVADPSDRAAF
                     DARWERFLGDPGIVSRTVLLGGEVVGSATVYPSHDDPGAREVTYWIAREHWGRGVAGRA
                     LAALLAEHPHRPLYARAAKDNHGSLRVLEKCGFVRCGEDAGYAAARGETVEEYLLVLC"
     gene            complement(6185..6628)
                     /locus_tag="BMY40_RS25710"
                     /old_locus_tag="SAMN05216481_12143"
     CDS             complement(6185..6628)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063320.1"
                     /locus_tag="BMY40_RS25710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12143"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_245770329.1"
                     /transl_table=11
                     /translation="MTGAADSIPGAPGPARRLIDTVAWVHLRDGTVLGARTRGKDLFYI
                     PGGKRHAGESDEQTLLREVEEELTVAIVPGTAVHMGTYEAPVDADTPEVVVRMACYTGD
                     YRGTLAAAGEIEEIRRLTYADRDLVPPVDQLVFDELHAEGRLP"
     gene            complement(6625..7017)
                     /locus_tag="BMY40_RS25715"
                     /old_locus_tag="SAMN05216481_12144"
     CDS             complement(6625..7017)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471400.1"
                     /locus_tag="BMY40_RS25715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12144"
                     /product="VOC family protein"
                     /protein_id="WP_093663178.1"
                     /transl_table=11
                     /translation="MPARIKDLVVDAADHQALADWWCAALGYERRRPLGHPPPPPEWAV
                     AIHHPQDAGPVIWFNPVPGPKAGRNRVRFDVWGDTGELLALGATMVRRQTEDSGWDVLA
                     DPEGNEFGVFSPRASGLHLSGGGTTL"
     gene            7067..7729
                     /locus_tag="BMY40_RS25720"
                     /old_locus_tag="SAMN05216481_12145"
     CDS             7067..7729
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824124.1"
                     /locus_tag="BMY40_RS25720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12145"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_093663179.1"
                     /transl_table=11
                     /translation="MSAERILVFTRTTGYRHDSIPQGIEAFRDLGGGLGLTVEATEDPG
                     VLATALDGCRAVVFLSTSGEVLTPESREALREYAAAGGAFVGVHAAATTEYDWPWYGDL
                     LGARFERHPELQPGVAVVEDRDHPATAHLDAAWPFTDEWYDFRASPRGRVRVLLSADES
                     TYEGGGMGEDHPLAWCHENTGGRSFYTALGHSPEAYADPAFRRHLLGGLAWAARLVP"
     gene            complement(7766..8947)
                     /locus_tag="BMY40_RS25725"
                     /old_locus_tag="SAMN05216481_12146"
     CDS             complement(7766..8947)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063867.1"
                     /locus_tag="BMY40_RS25725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12146"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_093663180.1"
                     /sec_met_domain="DAO (E-value: 8.7e-09, bitscore: 27.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVVGAGPVGLTAALALRARGREVTLLEAEPEGRRRPGSRALFVH
                     GGTLRLLERVAPGLGARIAAYGVVWPERRTLYRGREVYARTYPPGPAGGGLPPFTSLRQ
                     VDTERFLLEACAAAGVRIVWDAPVRDVRSASDGVTVSAGDGRSWRAPYVIAADGARSAV
                     RRSLGIAMEGPRPPGFHVVVDLADGGRAPLPSARIFHYEHPGAAGRSVMLVPFAGGLQV
                     DLQCRESDDPGFFATPEGAREWLPHVLPAPCSEHLLWVARYRFRLVVADAFTDVRRRVL
                     LAGEAAHLFPPFGARGMNSGMADAVAAADAVADAETSRDRDPVHRFAEERRTAALHNRA
                     AAGEALRHLRPGGARRLRQRVSAALAPRVPSLGRWLEMAPYGPRSGPTAGSRY"
     gene            complement(8944..10560)
                     /locus_tag="BMY40_RS25730"
                     /old_locus_tag="SAMN05216481_12147"
     CDS             complement(8944..10560)
                     /NRPS_PKS="Domain: AMP-binding (33-433). E-value: 7.8e-84.
                     Score: 273.5. Matches aSDomain:
                     nrpspksdomains_BMY40_RS25730_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433572.1"
                     /locus_tag="BMY40_RS25730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12147"
                     /product="AMP-binding protein"
                     /protein_id="WP_093663181.1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-92, bitscore:
                     301.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKGCVPWPDEFAHRYREAGHWRGELLGDLVRPWARRDPARIALV
                     GGGARWSYAELDRRADRLAAGLAARGMAPRERVVVQLPNVPELVVLCLALFRLGALPVF
                     ALPAHRESELRHLLEASAASWLVVPDRYLGEDHRALARRVGGVGRERVLVAGDAEEFTA
                     LGDADADPVPLPPPDPGDVALFLLSGGTTGLPKLIPRTHQDYVYNLRITAENARLGPGD
                     AYLAVLPVAHNYALGCPGALGTLHVGGKVVLAPTPSIDDTFPLIERERVTVTGLVPPLA
                     LLWKDAAAALPADLSSLRLVQVGGAKFGAEAARTFGPALGCSLQQSFGMAEGLLCQSAP
                     DDPPEVVATTQGRPLSPADEIRVVDSRGADVAPGEPGELLTRGPYTIRGYYRAEEHNAV
                     AFTPDGYFRTGDLVRLLPGGHLVVEGRIKDQINRGGDKIAAEELENHLLGHPRIHDCAV
                     VATPDALLGERVCVFVVPRGEHAPDRAEVTRFLRERGVAAFKLPDRVERIGSLPRTAVG
                     KVDKNRLRSTARRTSEAGGAS"
     aSDomain        complement(9262..10461)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25730_AMP-binding.1"
                     /evalue="7.80E-84"
                     /label="BMY40_RS25730_AMP-binding.1"
                     /locus_tag="BMY40_RS25730"
                     /protein_end="433"
                     /protein_start="33"
                     /score="273.5"
                     /specificity="substrate consensus: diOH-Bz"
                     /tool="antismash"
                     /translation="WARRDPARIALVGGGARWSYAELDRRADRLAAGLAARGMAPRERV
                     VVQLPNVPELVVLCLALFRLGALPVFALPAHRESELRHLLEASAASWLVVPDRYLGEDH
                     RALARRVGGVGRERVLVAGDAEEFTALGDADADPVPLPPPDPGDVALFLLSGGTTGLPK
                     LIPRTHQDYVYNLRITAENARLGPGDAYLAVLPVAHNYALGCPGALGTLHVGGKVVLAP
                     TPSIDDTFPLIERERVTVTGLVPPLALLWKDAAAALPADLSSLRLVQVGGAKFGAEAAR
                     TFGPALGCSLQQSFGMAEGLLCQSAPDDPPEVVATTQGRPLSPADEIRVVDSRGADVAP
                     GEPGELLTRGPYTIRGYYRAEEHNAVAFTPDGYFRTGDLVRLLPGGHLVVEGRIKDQIN
                     R"
     CDS_motif       complement(9358..9444)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25730_0001"
                     /evalue="3.60E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="BMY40_RS25730"
                     /protein_end="401"
                     /protein_start="372"
                     /score="13.0"
                     /tool="antismash"
                     /translation="PGEPGELLTRGPYTIRGYYRAEEHNAVAF"
     gene            complement(10560..11198)
                     /locus_tag="BMY40_RS25735"
                     /old_locus_tag="SAMN05216481_12148"
     CDS             complement(10560..11198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075280.1"
                     /locus_tag="BMY40_RS25735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12148"
                     /product="DUF2461 domain-containing protein"
                     /protein_id="WP_218158322.1"
                     /transl_table=11
                     /translation="MKFQGFPDRAFEFYAGLEKDNSKEYWHSLKDVYDTCVRTPVEALA
                     EALEERYGPVKVWRPQRDVRFSNDKSPYKTYQGITAGSADSVGYYAQLSAEGLRLGAGF
                     HGGTEQLGRYRDAVDDERHGPELERIVRKLERNGWSLVGERLRTRPRGFPADHPRLELL
                     RYRSLGAERLHPPTELHGPEALDLVRKGWSGLKPLTDWLEARVSGEGRP"
     misc_feature    11164..11179
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            complement(11221..12417)
                     /locus_tag="BMY40_RS25740"
                     /old_locus_tag="SAMN05216481_12149"
     CDS             complement(11221..12417)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884643.1"
                     /locus_tag="BMY40_RS25740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12149"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_218158323.1"
                     /transl_table=11
                     /translation="MDSAVTPTAPAGVRRARQQPPWPDGDELAQVEAELAARPGLVTEG
                     EYTALRDALARASRGEALVLQAGDCAERFADAAPAAVDRRAEYLYSLADAMSTASGLPV
                     VPLGRMAGQYAKPRSAESETRADGVRLPVYRGDAVNGPEAEPPARSCDPRRLLAAYDHA
                     AAVLGRVRATWPGRPAGRRLYVSHEGLLCAYESPLERRGADGVHASSAHSVWIGDRTRA
                     LDGWHVEWAAGLGNPVGVKLGPSITPAEAVRLSHVLNPAGVEGKLLFIVRLGAGPARRL
                     LPGLVAEVALRGAPVVWLCDPLHGNTWRLRSGRKTRPVEAVRDEVSVFARIVRAHRQWP
                     AGLHLETTPEDVTECVSAPDHTPVPALRVAFPRYTSACDPRLNPGQTADVLARFAESL"
     gene            complement(12402..13217)
                     /locus_tag="BMY40_RS25745"
                     /old_locus_tag="SAMN05216481_12150"
     CDS             complement(12402..13217)
                     /EC_number="1.4.3.5"
                     /GO_function="GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF004231.0"
                     /locus_tag="BMY40_RS25745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12150"
                     /product="pyridoxal 5'-phosphate synthase"
                     /protein_id="WP_342745092.1"
                     /transl_table=11
                     /translation="MATETECPGLGDLPVAFPEADYSFTITRFHSLPPLSFPKEAYARR
                     DVTLRVERIREGNPVQEGTEKRRDRLMREGMGDADAVGDPLVRFRDWHREWARTRPYDA
                     AAAVLATADAEGRPTARFVDLARTDHGFVFFTGHRSRKALDLAVNPWAQLCFGWLDLGR
                     QVRAAGPVERLDPLACDDHYTRLPRPVQLLAWATDQQAVVSGSGAVRDAVASAAERFAG
                     QEVPRPEEWGGFRLVPESVEFWQDRADHVPDRLRYQLTDSGWSRQWIAP"
     gene            13239..13838
                     /locus_tag="BMY40_RS25750"
                     /old_locus_tag="SAMN05216481_12151"
     CDS             13239..13838
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025217.4"
                     /locus_tag="BMY40_RS25750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12151"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_218158325.1"
                     /transl_table=11
                     /translation="MYAPNLTPSALLYAEWVPYPVGGSFCEIGSGTGYIAVTAAHRGCD
                     RVTAIDIGPVSAENTRKNAERHGVSDRVTVLCGDMFEPLTENDRYDVVFWNSNFVEASF
                     GDPAAPEGPEADRDAMLDLAFCDPGYATHRKFFDGVRDHLNPGGRVLLGFTDLGDDELL
                     ERVAREHGWSPVPRRRAVGVYPDGELRYELLELLPV"
     gene            complement(13914..14666)
                     /locus_tag="BMY40_RS25755"
                     /old_locus_tag="SAMN05216481_12152"
     CDS             complement(13914..14666)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="BMY40_RS25755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12152"
                     /product="ABC transporter permease"
                     /protein_id="WP_093663185.1"
                     /transl_table=11
                     /translation="MTVVFEASVLAGRNIRRFLRSPQLLGDALAFPLILLVALYVMFQE
                     VVGGAGDEPYIARLTPGIALFSVAYSCTGTAVGFYGDLRGGFQDRLRTLPIGRSAGLLG
                     RITGDLVKFVLVTAVTVLVGCLLGFRFERGAVAAVGFLLVVVAFASIFLWLAVVTALSA
                     GSQETASGLLNAPVTLLLLLSTTLVPAEAFPGFVQPVVRANPLSCAHGALMGLSSGGPV
                     LVPVLQTLAWVVAATAVLAPLAVRLGRR"
     gene            complement(14663..15469)
                     /locus_tag="BMY40_RS25760"
                     /old_locus_tag="SAMN05216481_12153"
     CDS             complement(14663..15469)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024110.4"
                     /locus_tag="BMY40_RS25760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12153"
                     /product="ABC transporter permease"
                     /protein_id="WP_093663186.1"
                     /transl_table=11
                     /translation="MTTTTERPRAGASTERGAGNLAAQGLVLAARNLRRGANAQSVVVY
                     TVFPLVFVFGFLMLFGRIFEERGLDYAQFLTPAIVVQWMFTVANTSGVATASDRDSGML
                     SRCRWMPLNRGAFVAGRLVSDVVWALVAVVVIGAAGHLAGFRFQGPVLAVAGFVALAVA
                     FALTLTAATTAVGLVSAGPEAASATLNLPYLVLILLSTAFVPASAFPDWLEPAVEASPV
                     SSVIDALRSLASASPSAGEVWPALAWIAGLLAVGAWASTKAFGRAR"
     gene            complement(15466..16422)
                     /locus_tag="BMY40_RS25765"
                     /old_locus_tag="SAMN05216481_12154"
     CDS             complement(15466..16422)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019329117.1"
                     /locus_tag="BMY40_RS25765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12154"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_093663187.1"
                     /transl_table=11
                     /translation="MPGAGIEVEGLRKRYGEKTALEDVTFSVAPGTLLGLLGHNGAGKT
                     TTIDCLTTLLRPDGGHARVAGHDVVAEPEEVRRSIALTGQFAALDEMLTGRENLVLFGR
                     LLRLGARNAARRADELLERFRLSDAGGRPVKEYSGGMRRRLDLAAGLVVDRPVLFLDEP
                     TTGLDPRSREEVWSVVEELRRGGTTTLLTTQYLEEADRLADRVVVLGSGRVTAEGTPGE
                     LKDRVGGRVCEVKVAPERHDEAAAALRRALGEVSGRNGTLVVPAPRTSVVAQVLGLLEH
                     EGVDPENVTLRKPSLNEVFFALTDPEAAPGPPEESRT"
     misc_feature    16417..16431
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.57"
                     /tool="antismash"
     misc_feature    complement(16419..16430)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.67"
                     /tool="antismash"
     gene            complement(16474..16863)
                     /locus_tag="BMY40_RS25770"
                     /old_locus_tag="SAMN05216481_12155"
     CDS             complement(16474..16863)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025887.4"
                     /locus_tag="BMY40_RS25770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12155"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_093663188.1"
                     /transl_table=11
                     /translation="MAEIDRITMEKELFALEEAGWEAISSANGDFYRRLVTPETLVVEH
                     DGVATGDDLVAEIDGNESPFENFRLDDRRLVPLSPDSAVVTYRATADVTGRGTFRLYMS
                     SVWVRREEGWKLMFHQQTPASQQEG"
     misc_feature    16848..16862
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     misc_feature    16898..16912
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.09"
                     /tool="antismash"
     gene            complement(16968..17807)
                     /locus_tag="BMY40_RS25775"
                     /old_locus_tag="SAMN05216481_12156"
     CDS             complement(16968..17807)
                     /NRPS_PKS="Domain: Thioesterase (40-263). E-value: 4.1e-54.
                     Score: 176.3. Matches aSDomain:
                     nrpspksdomains_BMY40_RS25775_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638157.1"
                     /locus_tag="BMY40_RS25775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12156"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_093663189.1"
                     /sec_met_domain="Thioesterase (E-value: 2.4e-55, bitscore:
                     180.1, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 9.2e-07, bitscore: 20.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.7e-15, bitscore:
                     48.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLNRTTRIVTGPGRGEEERRRWLRPLGGQGPGSGGGQRIRLVCF
                     PHAGGAAGSFRPFAPLLPGGVDLLAVQYPGRHDRTGEPCATRMDELAGPLAAALAPVSG
                     DGLVLLGHSMGAAVAAEVAARLEERTGSSLLRLFVSGRPAPGTRDPVSVHEGGDEALLA
                     DLKRLGGTDEALFSDPALQSLVLPSLRADYRLIETYRPPEGRRLRTPITALTGDSDPEV
                     TPEEAEAWRSCSSGPFRLHVFPGGHFYLLERPVAVLGAVLADLGRGAPAGLEWPSTP"
     aSDomain        complement(17019..17687)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25775_Thioesterase.1"
                     /evalue="4.10E-54"
                     /label="BMY40_RS25775_Thioesterase.1"
                     /locus_tag="BMY40_RS25775"
                     /protein_end="263"
                     /protein_start="40"
                     /score="176.3"
                     /tool="antismash"
                     /translation="RLVCFPHAGGAAGSFRPFAPLLPGGVDLLAVQYPGRHDRTGEPCA
                     TRMDELAGPLAAALAPVSGDGLVLLGHSMGAAVAAEVAARLEERTGSSLLRLFVSGRPA
                     PGTRDPVSVHEGGDEALLADLKRLGGTDEALFSDPALQSLVLPSLRADYRLIETYRPPE
                     GRRLRTPITALTGDSDPEVTPEEAEAWRSCSSGPFRLHVFPGGHFYLLERPVAVLGAVL
                     A"
     CDS_motif       complement(17430..17486)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25775_0001"
                     /evalue="1.50E-06"
                     /label="NRPS-te1"
                     /locus_tag="BMY40_RS25775"
                     /protein_end="126"
                     /protein_start="107"
                     /score="20.7"
                     /tool="antismash"
                     /translation="VLLGHSMGAAVAAEVAARL"
     gene            complement(17798..18898)
                     /locus_tag="BMY40_RS25780"
                     /old_locus_tag="SAMN05216481_12157"
     CDS             complement(17798..18898)
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="other (smcogs) SMCOG1099: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540265.1"
                     /locus_tag="BMY40_RS25780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12157"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_093663190.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 6.2e-21, bitscore:
                     67.3, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTANVVVCGTGFGRVYLRALEAGGPDAPRGAGDLRLTGVLARGSE
                     RSRACAERADVPLYTDPGQLPADTDIAVVAVYAGVNGGPGSELARQLMERGVHVLQEGP
                     LHHDELAESLRVARRAGVVFRVSTHYVRVEPVRRFIAAARRLTARRPVLYADAACGLQV
                     FYHLFDILRLALGGLRPWSFEDARPTPVFHTLTGTVRDVPLTLRVQNQLNPSDPDNHAH
                     LLHRITLGTDGGSLTLSDTHGPLLWSPRPHFPSEERSLTRLEEAASGHLDHAATTPLGD
                     AAAPSYREVVGRLWPDAALRALTELHEAVREGHHPLAEGHAQLAVSHAWRDAAVRLGPP
                     ELTDATAVRPIGAGELAGELEVPRCT"
     gene            complement(18895..20004)
                     /locus_tag="BMY40_RS25785"
                     /old_locus_tag="SAMN05216481_12158"
     CDS             complement(18895..20004)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015400.4"
                     /locus_tag="BMY40_RS25785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12158"
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="WP_143071824.1"
                     /transl_table=11
                     /translation="MTAVLGLLGSGGAVGRHVAPLLVDGGARVLLGGRDRARLDRSPGH
                     ERVVVDVDDPHGLERFARRCDVVVDCTGPARRTAPRVLRAALAGGAHYVGASGGELLDG
                     PGSGEFGDPDGGLCAVLGAGMAPGLSALLPRALAAGLGRPERLVAYAGGRDRFTWASAQ
                     DYVAGARDGGGRSLSAWSGGCRVPGALTPLTGAELPFFPGPVTAYPFLSAETERLARDL
                     GLAEAHWYNVFDGGHALRALSSPSDGDLREAAGRLVRAAELDLFGRTPYQLMVFRLEGE
                     RDGRPHRRTLVLRADDSYALTAAFTAFAVRCVLAGEVAPGPLPADEAVDARTAPDRLAA
                     MPGVGHLRIVEDAPPVEEEDAPPVEEGVL"
     gene            complement(20001..25559)
                     /locus_tag="BMY40_RS25790"
                     /old_locus_tag="SAMN05216481_12159"
     CDS             complement(20001..25559)
                     /NRPS_PKS="Domain: Heterocyclization (74-369). E-value:
                     2.1e-107. Score: 350.9. Matches aSDomain:
                     nrpspksdomains_BMY40_RS25790_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (542-939). E-value: 4.4e-97.
                     Score: 317.2. Matches aSDomain:
                     nrpspksdomains_BMY40_RS25790_AMP-binding.1"
                     /NRPS_PKS="Domain: cMT (1155-1294). E-value: 2.9e-44.
                     Score: 142.6. Matches aSDomain:
                     nrpspksdomains_BMY40_RS25790_cMT.1"
                     /NRPS_PKS="Domain: PCP (1439-1514). E-value: 1.3e-18.
                     Score: 59.0. Matches aSDomain:
                     nrpspksdomains_BMY40_RS25790_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031723.1"
                     /locus_tag="BMY40_RS25790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12159"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_245770331.1"
                     /sec_met_domain="Condensation (E-value: 4.7e-47, bitscore:
                     152.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8e-105, bitscore:
                     342.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7e-09, bitscore:
                     28.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 3.4e-12, bitscore:
                     39.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSADTARTPETLVADLRERGVRLWEDGGRLRFRAPRGVLTDEW
                     REALAAHKEAVLACLRAESPAVVRDPEHRYDPFPLTDVQSAYLLGRREAFAYGGVGCQV
                     YAEMEYAELDPARLESAWNRLVGRHDMLRAVISLDGHQRVLPEVPDYRIEVTDVRGASP
                     AEADRARAEVRAAMDHSVHDPERWPLFALRVTLTDACAVLHVSVDFLIADYLSVRTLMR
                     ELRMLYDGLTPPPLDITFRDYLSAAARRRESPAHERDRQYWARRLDELPAAPELPVREG
                     AEYLPGRFRRLSSTLSPEQWQAVRRASARWNLTPSAAVLAALAEVIGRWSAKPRFCLNL
                     TLLNREPLHPQVDRLVGDFTTVSPLAVDTAPLSAFGERARALQQRMWEDMDHRLYSGVE
                     VMREMARRRGSAAALLPVVFTSTLGTAGDAGGPGEAAAQDDPAERPVHGISQTPQVWID
                     AQAVESDGCLDLRWDVREGVLLPGVAEEMFDVLVALLRRLGKDAAVWEEPSPVPLPRAQ
                     QRRRDAANDTAAPLPDALLHDDLVTAARAHPDRPAVVSSGRTLSHGELLGRAEAVAARL
                     QEAGCTPGEVVGLVMDKGWEQVAGALGTLLAGCAYLPLDASQPRLRRERILDDAGVRHV
                     LVQSWSLPGDDCGRHAVAVDALAVREGGGKSAGAPPAGPDDLAYVVYTSGSTGAPKGVM
                     VSHRAALNTLRDVSRRFDVTAEDRVLGLAGMGFDLSVYDVFGVLGAGGTLVLPDPERRA
                     DPSHWAQLLAEHRVTVWNSVPAQLQLLEDYLAVEPAAGLDALRLALLSGDWIPVALPDR
                     VRRRLPGLRLVSLGGATEAAVWSIAHPIGEVDPDWRSIPYGRPLTNQTFHVLDPWLRSC
                     PEHVPGELYIGGAGLALGYLGDAARTAERFVYHPRTGERLYRTGDRGVYREDGVIEFLG
                     RQDRQVKIRGHRIELAETEAALSSHPAVASAHALVDGDGPLDRRLLAYARLATGARSVP
                     DCGAERLLAAASARGDAAVRDVDPAELSEFMRRLDRAGLLAMLHAFNRQGLFRSPGDRH
                     TVPEVLEATAAAPCHHRLVRRWLKSLTEAGLLTRHGDAYAAAGPVSGEDLDAAWREVDA
                     LQREEWYRADLIGYFRTCAERLPELLRDEIDPLPLLFPEGGLDLSYAAYRDNVLSRYVN
                     HAVVGLVRELAAAHEGPLRLLEVGAGVGGTSTVLVPEIADTDVRYLFTDVSQFFLGEAR
                     RRFGDRVDYGLFDINGDAREQGRLPNSQDVVLCANVLHNARHVDTVLARLRELLAPGGW
                     LVFIETTQENVQIMTSMEFMMPDRDPAKWDYEDLRRGRDQTFLDSGQWRRLLREAGADT
                     VLELPHADGVTAPLGQRVFAARFKADRIPVRPEDVLEHAARRVPEYMLPARLELLDDLP
                     LTANGKTDTAVLRGWAERHRAPDDPGLPGGTEHLDDLERRVAAVWADLLRLPRVGRDDD
                     FYRLGGDSLLVARLAGRVREEIPEAAGLLYDTVLRAVLSRPTVAALAEFLRDSREHTEG
                     TGGDGPADSPLVPLGGAGPSGSGAEGPEGAEGAAMRVLVHDGMGTLAAYRPLIPLLDGP
                     GPLVGLAVPAHEPYAREDPEDLIVRRAAHYTRCLLETGHTRFQVVGYCMGGLLATEVAR
                     QLAESGALVENLTIVSSYALPHTVEDELVLEYVFARLLNADTEELGYPDDTATAHVFRA
                     VLEHTPGRVPSGSPDSLTGDPVVEEAARRFAALRKVPQRERLAAIGRAARGDGDGDGDG
                     FPVDLEAVYSLYRTSMTAVTRHRATPYAGDVVLLREDEATGFLPWLRADMTEFWRELCL
                     GDLEIVDVPGDHFSCMRPPHVGRVARELDRLHRGGGR"
     CDS_motif       complement(20640..20696)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0013"
                     /evalue="7.10E-07"
                     /label="NRPS-te1"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="1640"
                     /protein_start="1621"
                     /score="21.7"
                     /tool="antismash"
                     /translation="QVVGYCMGGLLATEVARQL"
     aSDomain        complement(21018..21242)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25790_PCP.1"
                     /evalue="1.30E-18"
                     /label="BMY40_RS25790_PCP.1"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="1514"
                     /protein_start="1439"
                     /score="59.0"
                     /tool="antismash"
                     /translation="ERRVAAVWADLLRLPRVGRDDDFYRLGGDSLLVARLAGRVREEIP
                     EAAGLLYDTVLRAVLSRPTVAALAEFLRDS"
     aSModule        complement(21018..25337)
                     /complete
                     /domains="nrpspksdomains_BMY40_RS25790_Heterocyclization.1"
                     /domains="nrpspksdomains_BMY40_RS25790_AMP-binding.1"
                     /domains="nrpspksdomains_BMY40_RS25790_cMT.1"
                     /domains="nrpspksdomains_BMY40_RS25790_PCP.1"
                     /locus_tags="BMY40_RS25790"
                     /monomer_pairings="Cys -> Me-Cys"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(21678..22094)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25790_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="2.90E-44"
                     /label="BMY40_RS25790_cMT.1"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="1294"
                     /protein_start="1155"
                     /score="142.6"
                     /tool="antismash"
                     /translation="YRDNVLSRYVNHAVVGLVRELAAAHEGPLRLLEVGAGVGGTSTVL
                     VPEIADTDVRYLFTDVSQFFLGEARRRFGDRVDYGLFDINGDAREQGRLPNSQDVVLCA
                     NVLHNARHVDTVLARLRELLAPGGWLVFIETTQEN"
     CDS_motif       complement(22713..22778)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0012"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="949"
                     /protein_start="927"
                     /score="33.5"
                     /tool="antismash"
                     /translation="FLGRQDRQVKIRGHRIELAETE"
     aSDomain        complement(22743..23933)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25790_AMP-binding.1"
                     /evalue="4.40E-97"
                     /label="BMY40_RS25790_AMP-binding.1"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="939"
                     /protein_start="542"
                     /score="317.2"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="AARAHPDRPAVVSSGRTLSHGELLGRAEAVAARLQEAGCTPGEVV
                     GLVMDKGWEQVAGALGTLLAGCAYLPLDASQPRLRRERILDDAGVRHVLVQSWSLPGDD
                     CGRHAVAVDALAVREGGGKSAGAPPAGPDDLAYVVYTSGSTGAPKGVMVSHRAALNTLR
                     DVSRRFDVTAEDRVLGLAGMGFDLSVYDVFGVLGAGGTLVLPDPERRADPSHWAQLLAE
                     HRVTVWNSVPAQLQLLEDYLAVEPAAGLDALRLALLSGDWIPVALPDRVRRRLPGLRLV
                     SLGGATEAAVWSIAHPIGEVDPDWRSIPYGRPLTNQTFHVLDPWLRSCPEHVPGELYIG
                     GAGLALGYLGDAARTAERFVYHPRTGERLYRTGDRGVYREDGVIEFLGRQDRQVKIR"
     CDS_motif       complement(22857..22946)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0011"
                     /evalue="4.30E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="901"
                     /protein_start="871"
                     /score="44.6"
                     /tool="antismash"
                     /translation="PEHVPGELYIGGAGLALGYLGDAARTAERF"
     CDS_motif       complement(23322..23357)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0010"
                     /evalue="2.60E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="746"
                     /protein_start="734"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="FGVLGAGGTLVL"
     CDS_motif       complement(23469..23528)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0009"
                     /evalue="3.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="697"
                     /protein_start="677"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYVVYTSGSTGAPKGVMVSH"
     CDS_motif       complement(23715..23756)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0008"
                     /evalue="2.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="615"
                     /protein_start="601"
                     /score="11.6"
                     /tool="antismash"
                     /translation="LGTLLAGCAYLPLD"
     CDS_motif       complement(24168..24215)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0007"
                     /evalue="1.40E-06"
                     /label="Cy7"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="464"
                     /protein_start="448"
                     /score="21.1"
                     /tool="antismash"
                     /translation="ISQTPQVWIDAQAVES"
     CDS_motif       complement(24348..24395)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0006"
                     /evalue="4.10E-07"
                     /label="afterCy5"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="404"
                     /protein_start="388"
                     /score="22.3"
                     /tool="antismash"
                     /translation="DMDHRLYSGVEVMREM"
     aSDomain        complement(24453..25337)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25790_Heterocyclization.
                     1"
                     /evalue="2.10E-107"
                     /label="BMY40_RS25790_Heterocyclization.1"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="369"
                     /protein_start="74"
                     /score="350.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DFLIADY"
                     /tool="antismash"
                     /translation="YDPFPLTDVQSAYLLGRREAFAYGGVGCQVYAEMEYAELDPARLE
                     SAWNRLVGRHDMLRAVISLDGHQRVLPEVPDYRIEVTDVRGASPAEADRARAEVRAAMD
                     HSVHDPERWPLFALRVTLTDACAVLHVSVDFLIADYLSVRTLMRELRMLYDGLTPPPLD
                     ITFRDYLSAAARRRESPAHERDRQYWARRLDELPAAPELPVREGAEYLPGRFRRLSSTL
                     SPEQWQAVRRASARWNLTPSAAVLAALAEVIGRWSAKPRFCLNLTLLNREPLHPQVDRL
                     VGDFTTVSPLAVDT"
     CDS_motif       complement(24456..24515)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0005"
                     /evalue="8.20E-09"
                     /label="Cy5"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="368"
                     /protein_start="348"
                     /score="27.6"
                     /tool="antismash"
                     /translation="HPQVDRLVGDFTTVSPLAVD"
     CDS_motif       complement(24516..24554)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0004"
                     /evalue="5.30E-04"
                     /label="afterCy4"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="348"
                     /protein_start="335"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FCLNLTLLNREPL"
     CDS_motif       complement(24567..24626)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0003"
                     /evalue="1.00E-07"
                     /label="Cy4"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="331"
                     /protein_start="311"
                     /score="24.6"
                     /tool="antismash"
                     /translation="NLTPSAAVLAALAEVIGRWS"
     CDS_motif       complement(24912..24956)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0002"
                     /evalue="3.60E-04"
                     /label="Cy3"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="216"
                     /protein_start="201"
                     /score="13.8"
                     /tool="antismash"
                     /translation="VLHVSVDFLIADYLS"
     CDS_motif       complement(25155..25226)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25790_0001"
                     /evalue="1.20E-09"
                     /label="C2_DCL_024-062"
                     /locus_tag="BMY40_RS25790"
                     /protein_end="135"
                     /protein_start="111"
                     /score="30.4"
                     /tool="antismash"
                     /translation="ELDPARLESAWNRLVGRHDMLRAV"
     CDS             complement(25556..>27548)
                     /NRPS_PKS="Domain: AMP-binding (88-481). E-value: 2e-97.
                     Score: 318.3. Matches aSDomain:
                     nrpspksdomains_BMY40_RS25795_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (590-658). E-value: 1.2e-25. Score:
                     81.5. Matches aSDomain: nrpspksdomains_BMY40_RS25795_PCP.1"
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="BMY40_RS25795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_12160"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_143071825.1"
                     /sec_met_domain="AMP-binding (E-value: 4.1e-106, bitscore:
                     346.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-17, bitscore:
                     55.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SQTPQVWLDHQVIEQDGGLLLVWDAVEELFPPGVLDAMFTTYTRL
                     LDHLGDHDWNTPLPPLLPPEQRIVRAAANDTTGPLPDTLLHDGFFAHAARTPHRTALLT
                     QDDHVTYHDLADQALRIAATLRDRGTTPGEPVGVTLPKGPDQIAAVLGVLAAGAAYVPV
                     GVDQPPERRKRMYQRAGVRTVLTRESMDAPPGEPAAVPLADCAASAPLDAPLPGNPDGL
                     AYVIFTSGSTGEPKGVAVSHRAAMNTITDLNDRCHVTADDRVLALSALDFDLSVYDTFG
                     LLTAGGTLILPHHDHRTDPDHWHHLAHTHHPTIWNTVPALLDMLLTTTTDDHPLPHTLR
                     LALVSGDWVPLDLHPRLTHHLPHCTLIALGGATEAGIWSNHHHITTVPPHWTSIPYGRP
                     LRNQHYRVVNHHGHDAPDWVPGELWIGGHSLALGYHNDPHTTNRKFPRTHNTRWYRTGD
                     LGRYWPDGTLEFLGRTDHQIKINGHRIELGEIETALTQHPHITTATALKTPHTHQLAAA
                     VTPDSEAAGDDSALDDLEDFLAERLPSYAIPQVCLVLDAMPLTPNGKIDRRAVADLFSK
                     ERSGGGSQPPRGPAEEAVAAVWEELLGISGIHRDDNFFSLGGDSLIATRMAQALRERHG
                     VEVTLRQLFSAPTVAETAALIDSFEEGSL"
     gene            complement(25556..>27552)
                     /locus_tag="BMY40_RS25795"
                     /old_locus_tag="SAMN05216481_12160"
     aSDomain        complement(25574..25777)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25795_PCP.1"
                     /evalue="1.20E-25"
                     /label="BMY40_RS25795_PCP.1"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="658"
                     /protein_start="590"
                     /score="81.5"
                     /tool="antismash"
                     /translation="EEAVAAVWEELLGISGIHRDDNFFSLGGDSLIATRMAQALRERHG
                     VEVTLRQLFSAPTVAETAALIDS"
     aSModule        complement(25574..27283)
                     /complete
                     /domains="nrpspksdomains_BMY40_RS25795_AMP-binding.1"
                     /domains="nrpspksdomains_BMY40_RS25795_PCP.1"
                     /locus_tags="BMY40_RS25795"
                     /monomer_pairings="Cys -> Cys"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(26075..26140)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25795_0006"
                     /evalue="4.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="491"
                     /protein_start="469"
                     /score="37.8"
                     /tool="antismash"
                     /translation="FLGRTDHQIKINGHRIELGEIE"
     aSDomain        complement(26105..27283)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMY40_RS25795_AMP-binding.1"
                     /evalue="2.00E-97"
                     /label="BMY40_RS25795_AMP-binding.1"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="481"
                     /protein_start="88"
                     /score="318.3"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FFAHAARTPHRTALLTQDDHVTYHDLADQALRIAATLRDRGTTPG
                     EPVGVTLPKGPDQIAAVLGVLAAGAAYVPVGVDQPPERRKRMYQRAGVRTVLTRESMDA
                     PPGEPAAVPLADCAASAPLDAPLPGNPDGLAYVIFTSGSTGEPKGVAVSHRAAMNTITD
                     LNDRCHVTADDRVLALSALDFDLSVYDTFGLLTAGGTLILPHHDHRTDPDHWHHLAHTH
                     HPTIWNTVPALLDMLLTTTTDDHPLPHTLRLALVSGDWVPLDLHPRLTHHLPHCTLIAL
                     GGATEAGIWSNHHHITTVPPHWTSIPYGRPLRNQHYRVVNHHGHDAPDWVPGELWIGGH
                     SLALGYHNDPHTTNRKFPRTHNTRWYRTGDLGRYWPDGTLEFLGRTDHQIKIN"
     CDS_motif       complement(26213..26302)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25795_0005"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="445"
                     /protein_start="415"
                     /score="40.1"
                     /tool="antismash"
                     /translation="PDWVPGELWIGGHSLALGYHNDPHTTNRKF"
     CDS_motif       complement(26822..26881)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25795_0004"
                     /evalue="4.60E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="242"
                     /protein_start="222"
                     /score="34.4"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGEPKGVAVSH"
     CDS_motif       complement(27059..27097)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25795_0003"
                     /evalue="1.30E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="163"
                     /protein_start="150"
                     /score="12.3"
                     /tool="antismash"
                     /translation="LGVLAAGAAYVPV"
     CDS_motif       complement(27431..27460)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25795_0002"
                     /evalue="8.90E-04"
                     /label="afterCy7"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="39"
                     /protein_start="29"
                     /score="12.4"
                     /tool="antismash"
                     /translation="FPPGVLDAMF"
     CDS_motif       complement(27476..>27546)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMY40_RS25795_0001"
                     /evalue="1.50E-07"
                     /label="Cy7"
                     /locus_tag="BMY40_RS25795"
                     /protein_end="24"
                     /protein_start="0"
                     /score="24.1"
                     /tool="antismash"
                     /translation="SQTPQVWLDHQVIEQDGGLLLVWD"
ORIGIN
        1 ggtgccgttg acgacgggga agaggacggt gcgcagccac agcgtgtacc gctcccaggc
       61 agtccaccgg ccgatgcggt gctcggagag ggcgacccgg cgcgggccca gccggtgggc
      121 ctccaccgtc cgcccggcgt ccacggtctc ggccagggcg gcggcgacgg ccgcgtagcc
      181 ggccgcctcg gaacggtagg cgccgggcgc ccgccggtag taccagcggc agcccaccag
      241 cagcaccggc agggcgatca cgacggacag cgccagcggc ggcgcggtgg ccgtgagcgc
      301 gcccagcagc agcgccgccc agacgacgcc gatcgacaac tggggcaccg cctcgcgcat
      361 ggcgcccgcc aaccggtcga tgtcggtggt gatcctggaa agcagatccc ccgtaccggc
      421 ccgttccagc acacccggcg gcaaccgcac cgagcggacc aggaagtcct cgcggagatc
      481 cgccagcatc cgctcgccca gcaccgcccc gcgcagccgc acctgccgga cgaagaccgt
      541 ctggacggcc agcgcggcgg cgaacaggac aacggtgcgc tccaggtgcg gatcacgggc
      601 ccccgccgcg aggtcctcca ccacacgccc cagcagatag gggccgacca tggaggccag
      661 caccgcgacg gcgttcaccg acaccagtac ggcgaacggc ccgcggtggc gccggaccag
      721 ctcgccgacg taggcgcgca cggtccccgg cgcaccgacc ggcagggtcg cggccgactc
      781 ggacgcggcg ggatcgtggg cgggcggtgc gacgccgatc atgcgttctc ctccatctgc
      841 tcgtgccgcc gcggctcccg gaccccggcc gtaccggccg tggccctgcc ggtgcctgcg
      901 gtgccgtcgg tgccgttgtc gtcatcgccg ccggcctcgc gggcgaccac cgcgcggtac
      961 cccggctcgt ccgccagcag ctcccggtgc gtgccgacgg cggtcacctc gccgccggag
     1021 acgaacacca cccggtcggc ccggtccagc agcagcgggc tggaggagaa caccacagtg
     1081 gtgcggccgg cgcgcagccg gcgcagtgcg ccggcgacac gtgcctcggt gtgcgagtcg
     1141 acggcgctgg tcggttcgtc cagcaccagc acctgtggat cggcgaccag cgaccgggcc
     1201 agcgccagcc gctggcgctg gccgcccgac agcgacctgc cgcgctcggt gatccgggcc
     1261 cgcatcgggt cgccgtccgg ggcgcccccg gcgcgtacca gtgcggcgag cacatcgccg
     1321 cactgggccg cctccagcgc ccgcccgggt gcgaccgcgc ccgacgacgg tacgtcgagc
     1381 agttccccca aggtgcccga cagcagcacc gggtccttgt cctggaccag cacggcggta
     1441 cgggccgctt ccagcggcac gtcgtccagg gcgaccccgc ccagcagcac cgacggcccg
     1501 tccgttccgg atccggtgcc gtgcccgccc agccgttcgg cgagccgccc ggccgcgtcg
     1561 gggtcgccgc acaccaccgc cgtcagatcc ccggccggtg cgagcagccc gctcaccggg
     1621 tcgtacaggt cgccgtgcgg cagtcgcgca tcaccacccg cccgcgcggc gcccgcccgc
     1681 gtcaggcggc gcagacccag gacccgggcg gcccgctcgg ccgagggccg ggagaaggag
     1741 taggccatgg cgatctcctg gaagagccgc aacgggaaga gcaggaaggt caccgcgccg
     1801 tacaccgtca ccagctcgcc cacggcgacc ctgccgtcca gggccagccg cgtgcccagc
     1861 cagaccaccg cgatcagcag cagccccgga agcaccacct gcacggcgtc gatcagcgac
     1921 cacatccgcg cggtccgcac cgccgcccgc cgcacctcct gcgaggccct gcggtaccgg
     1981 tcgaggaaca gctcctcgcc cccgatgccg cgcagcaccc gcagcccggc cacggtgtcg
     2041 gcggccagct cggtggcccg ccccgccttc gcgcgctgcg cgtccgcccg gcgggtcgcc
     2101 ggcggcagca gcggcagtac ggccgacacc agcaccagca cgcccagcgt caccacgacg
     2161 cccagcagcg gctcgtacac caccagggcc gtacacaccc cggccgtggt cagcgaagcg
     2221 gcgccgaagc gggagacggc ctcgacgaac cagccgatct tctcgatgtc ccccgtggag
     2281 acggccacca cctcaccggc cgccacccgc cgggtcaggg cggcccccag ctcggcggtc
     2341 cgccgggcca gcaactgctg cacccgggcc gcggcggtga tccagttggt gacggcggcg
     2401 cggtgcagca tggtgtcgcc gacggtgacg gccaggccca gcgccaccgt cagggcgccc
     2461 gcgaggacca gccggtcccc ggaacgctcc gtggcggcct gtacggccat gcccacggcc
     2521 agggggaagg aggcgaccgc cgccatgtgg agcgtccccc aggccagcgc cttcagctgg
     2581 ccgcccagct gtgagcgcca cagccagagc atgaggcgga acccggaccg tacgtcgggt
     2641 tcgccgggat cgggatacgg aagatcgcga atgcgcatga cgccccggaa acggtctcga
     2701 tggcggagaa gcggaaacga ccgtgcaagc cttccgtcat atccggcggg agggcaaagg
     2761 gttttccacc cggaggatgg gacgatgtac ggcatgagca ggcccggtac acggttcgga
     2821 ctcggtgccc ggcgcagggc gtcggcggtc tgcgccgccg cgacggcgct cctgctgctc
     2881 gcgggctgcg gaggcggggg cgcggccggg gccgacccct cctcccggcc ccggcaggag
     2941 gcgtcgcagc cgccctcccc gtccggagcc ggtgcccgcc gcatccccgg cgtcggtgag
     3001 cgcctccacg ccgagatccc cgaatcggcc cggcaggtcg tcgccgtcca cggcgcgggc
     3061 aaggactccg aggacgccac ggtcgccctc tacacccggc gcggcgagac ctggacgcgc
     3121 gagcgccgct ggcccgccca caacggcaag cggggctgga cgccggacca ccgcgaggac
     3181 gacaagcgca gcccggtcgg cgtcttcacc ctctccgacg ccggcggcgt cctccccgac
     3241 cccggggcga agctgccgta cacccgctcc gccgccttcg ccgcgccgcg ccactggccc
     3301 gagaggtacc ggcacgactt cgactacgtc atcgccatcg actacaaccg cgtcaggggc
     3361 accccgccca acgaccccac ccgtcctctg ggccgggaga agggcggcgg catctggctg
     3421 cacatggacc acggcagcgg gacctccggc tgtgtcagcc tctccagggc cgcgatggag
     3481 taccttctgc gcaccctgga tccggcacag cacccggtca tcgtgatggg cgacaggcag
     3541 agcctcgcct cctgaccggc atcctgccgc ccgctgcctg ccgctcgccg gccggcgtcc
     3601 tgtcggccac ccgcccgggc gcggcggcgc ccgggcacgc cgcgttggga gggcgaccgg
     3661 cgggcgggcg atcgtaggct ggtgagccgg ggccggcccg cccgagggcc ggccccgccc
     3721 accccgccgt ccgccccccg ccgagtgccg ggcaccggcc gccgaccccc gaaggagcgc
     3781 attgcaccgc gacgaacccg actggactcc accgcagagg cggaagggcg agccgcagcc
     3841 gcccgcccag atccgccgca tcctgcgcct cttccgcccc taccgcaggc ggctggccgt
     3901 ggtgggactg ctggtcggag cctcctcgct ggtgtcggtc gcctcgccgt tcctgctgcg
     3961 cgagatcctc gacgtggcca tccccgagca gcgcaccggc ctgctctccc tgctcgccct
     4021 cggcatgatc gccacggcgg tgctgaccag cgtcttcaac gtcctccaga cgctgatcag
     4081 caccaccgtc ggccagcacg tcatgcacga cctgcgcacc ggggtctacg ccaagctcca
     4141 gcggatgccc ctggcgttct tcacccgcac ccgcaccggc gaggtccagt cccgcatcgc
     4201 caacgacatc ggcgggatgc aggccacggt cacctccacc gcgacctccc tggtctccaa
     4261 cctcaccagc gtggtggcga cgatcgtggc catgctggtg ctggactggc ggctgacgct
     4321 ggtctccctg ctgctgatgc cgctgttcgt ctggataagc cgccgggtgg ggcgggaacg
     4381 caagaagatc gccacccggc ggcagaagca gatggcggcg atgtcggcga tggtgaccga
     4441 gtcgctgtcg gtcagcggca tcctgctggg ccgcaccatg ggccgcgccg actccctcac
     4501 ccgctccttc gccgaggagt cggagcggct ggcggatctg gagatccgct ccaacatggc
     4561 cggacgctgg cgcatgtcgg tgatcggcat catcatggcg gccatcccgg cgctgctgta
     4621 ctgggcggcc ggtctgctcc tccacctcgg cggtccggcc ttctccatcg gcaccctggt
     4681 cgccttcgtc accctccagc agggcctgct gcgcccgacc gtctcactgc tgagcacagg
     4741 cgtgcaggtg cagacctcgc tcgccctctt ccagcgcatc ttcgagtacc tggacctgcc
     4801 ggtggacatc accgagcccg cccggcccgt gaggctggag cgggcgcgcg gcgaggtccg
     4861 cttcgagaac gtcggcttct cctacgaccc gggctcggcc acccccacgc tcagcggcat
     4921 cgacctgacc gtcccggcgg gcagcagcct cgccgtcgtc ggcgccaccg gctccggcaa
     4981 gagcacgctg agctacctgg tgcccaggct gtacgacgtc accggcggcc gggtcaccat
     5041 cgacgggatc gacgtacggg aactggactt cgacaccctg gcccggacgg tcggcgtggt
     5101 gtcccaggag acgtacctct tccacgcctc cgtcgcggac aacctccgct tcgcccgccc
     5161 cggcgccacc gacgccgaga tcgaggcagc ggcccgcgcc gcccagatcc acgaccacat
     5221 cgcctcgctg cccgagggct acgacaccct cgtcggcgag cgcgggtacc gcttctcagg
     5281 aggggagaag cagcgcctgg cgctcgcccg caccatcctg cgcgacccgc ccgtcctcat
     5341 cctcgacgag gccaccagcg ccctggacac ccgcaccgag caggcggtcc agcgggccgt
     5401 cgacgcactg gccacgggcc gcaccacgct gaccatcgcc caccgcctgt cgaccatccg
     5461 cggcgccgac cagatcgtcg tcctggaagg cggccggatc gccgagcgcg gcacccacga
     5521 cgagctcgtc gcgcgcgacg ggcgctacgc ggccctgctg cggcgcgacg cggtcctccc
     5581 cgagtcggca ggtcccgagt cggccggtcc ccagcaggcc ggtcccgagc aggcggggcc
     5641 ggtggggccg gccggctcgg gaccgggagc cgtcgagacc gcccccgcct gagccgccgt
     5701 cagcacagca ccagcaagta ctcctccacc gtctccccgc gcgccgccgc gtatccggcg
     5761 tcctcgccgc agcgcacgaa gccgcacttc tccaggaccc gcagcgagcc gtggttgtcc
     5821 ttggccgcgc gggcgtacag cggccggtgc gggtgttcgg ccaggagagc ggccagtgcg
     5881 cgccccgcga cgccccggcc ccagtgctcg cgggcgatcc agtacgtgac ctcgcgcgcg
     5941 cccggatcgt cgtgggaggg gtagaccgtg gcgctgccga cgacctcgcc gccgaggagc
     6001 accgtccggc tcacgattcc ggggtcgccg aggaaccgtt cccagcgggc gtcgaaggcg
     6061 gcgcggtccg aggggtcggc gacggtgaag gccgccatcc ggttggcctc cgggtcgagc
     6121 tggatgcgga agagggaggg caggtcgccg ggtgcggtct cgcgcagttc cacggccggg
     6181 gcggtcacgg cagcctcccc tcggcgtgca gctcgtcgaa gaccaattgg tccaccggcg
     6241 gcaccaggtc gcggtcggcg taggtcagcc ggcggatctc ctcgatctcg ccggcggcgg
     6301 cgagcgtgcc gcggtagtcg ccggtgtagc aggccatccg caccaccacc tccggggtgt
     6361 ccgcgtccac cggagcctcg tacgtgccca tatggacggc cgtgcccggc acgatcgcca
     6421 cggtcagctc ctcctcgacc tcccgcagca gggtctgctc gtcgctttcc ccggcgtggc
     6481 gcttgccgcc cgggatgtag aagaggtcct tgccgcgggt acgggcgccc aggaccgtgc
     6541 cgtcgcgcag atgcacccac gccaccgtgt cgatgagcct gcgcgcgggg ccgggcgcac
     6601 cgggtatgga gtcggccgcg cccgtcacag cgtggtcccc ccgcccgaga ggtgcagtcc
     6661 cgaggcgcgc ggggagaaca cgccgaactc gttgccctcc ggatcggcca ggacgtccca
     6721 tccgctgtcc tcggtctgcc gccgcaccat ggtggcgccc agggcgagga gttcgccggt
     6781 gtcgccccac acgtcgaagc gcacccggtt ccggccggcc ttggggccgg gtaccgggtt
     6841 gaaccagatc accggaccgg cgtcctgcgg atggtggatg gccaccgccc actccggcgg
     6901 cgggggagga tggcccagcg gcctgcggcg ttcgtacccc agcgcggcgc accaccagtc
     6961 ggcgagcgcc tggtggtcgg cggcgtccac gaccaggtcc ttgatgcgtg ctggcatacc
     7021 gacgagcgta gcccgcggcg gtgccgggcc gggggaccat ggagtcatga gcgctgaacg
     7081 gatcctcgtc ttcacccgga ccaccggcta ccggcacgac tccatcccgc aagggatcga
     7141 ggccttccgc gatctcggcg gcggcctggg cctgaccgtc gaggccaccg aggaccccgg
     7201 tgtcctcgcc accgccctgg acggctgccg cgccgtggtc ttcctctcca ccagcggcga
     7261 ggtgctgacc cccgaaagcc gcgaggcgct gcgggagtac gccgccgcgg gcggcgcctt
     7321 cgtcggcgtg cacgccgcgg ccaccaccga gtacgactgg ccctggtacg gcgacctgct
     7381 cggcgcccgc ttcgagcggc accccgaact ccagccgggg gtggcggtcg tggaggaccg
     7441 cgaccacccc gcgaccgcgc acctggacgc cgcctggccg ttcaccgacg agtggtacga
     7501 cttccgggcc agtccgcgtg gccgggtccg ggtgctgctc tccgccgacg agtccaccta
     7561 cgagggcggc gggatggggg aggaccatcc gctggcgtgg tgtcacgaga acaccggggg
     7621 ccgctccttc tacaccgccc tgggccacag ccccgaggcc tacgccgacc ccgccttccg
     7681 gcgccatctg ctcggcggcc tggcatgggc ggcccggctc gtgccgtgat cccggggccg
     7741 ccgcgccgga gcgggccgga ggggttcagt acctgctccc cgccgtcggc ccggacctcg
     7801 gcccgtaggg agccatctcc agccaccgcc cgagggaggg cacccggggc gccagcgcgg
     7861 cggacacccg ctggcgcagc cgccgtgccc ctcccggacg caggtgccgc agtgcctcgc
     7921 ccgcggcggc ccggttgtgg agcgcggcgg tccgccgctc ctcggcgaac cggtgtaccg
     7981 ggtcccgatc ccgtgaggtc tccgcgtcgg ccacggcgtc ggccgccgcc acggcgtcgg
     8041 ccatgccgct gttcatgccg cgggcgccga agggcgggaa cagatgggcg gcctctccgg
     8101 ccaggagcac ccgacgccgc acgtcggtga aggcgtcggc caccaccagg cggaaccggt
     8161 agcgcgccac ccacagcaga tgctcggagc acggcgcggg cagcacgtgc ggcagccact
     8221 cccgcgcccc ctcgggtgtg gcgaagaagc cggggtcgtc ggactcacgg cactgcaggt
     8281 ccacctggag gccgccggcg aacggcacca gcatcacgct gcgccccgcc gccccggggt
     8341 gctcgtagtg gaagatcctg gccgacggca acggggcccg gccgccgtcc gcgagatcca
     8401 ccacgacgtg gaatcccggc ggcctcggcc cctccatggc gatgcccagg gacctgcgca
     8461 ccgccgaccg cgccccgtcg gccgcgatca cgtacggggc ccgccaggac ctcccgtccc
     8521 ccgccgagac ggtcacaccg tcggacgcgg aacggacatc gcggacgggc gcgtcccaca
     8581 cgatgcgcac cccggccgcc gcgcaggcct ccagcaggaa ccgctcggtg tccacctggc
     8641 gcaggctggt gaacggcggg agtcccccgc ccgccggacc cggcggatag gtacgggcgt
     8701 agacctcccg gccgcggtag agagtcctgc gctccggcca caccacgccg tacgcggcga
     8761 tgcgggctcc caggcccggc gcgacgcgct ccagcaggcg cagtgtcccg ccgtgcacga
     8821 acagcgccct gctgcccggc cgccgcctgc cctcgggctc ggcctccagc agcgtcacct
     8881 cccggccgcg ggcccgcagc gcgagcgccg ccgtcagccc gaccggaccc gcacccacca
     8941 cgatcacgag gcacctcccg cttcggacgt ccgccgcgcc gtcgaccgca gcctgttctt
     9001 gtccaccttg ccgacggcgg tacggggcag ggagccgatc cgctccaccc ggtccggcaa
     9061 cttgaaggcg gccacacccc gctcccgcag gaaccgcgtc acctccgcac ggtcgggggc
     9121 gtgctccccg cgcggcacga cgaagacgca cacccgctcc ccgagcagcg cgtccggcgt
     9181 cgccaccacc gcgcagtcgt ggatccgcgg gtggccgagc aggtggttct ccagttcttc
     9241 cgcggctatc ttgtcgccgc cccggttgat ctggtccttg atccgtccct cgaccaccag
     9301 gtgccccccg ggcaggagcc ggacgaggtc gccggtccgg aagtagccgt ccggggtgaa
     9361 ggcgaccgcg ttgtgctcct cggcccggta gtagccgcgg atggtgtagg ggccgcgggt
     9421 cagcagctcg cccggctcac cgggcgcgac gtccgccccc cgggagtcca cgacgcgtat
     9481 ctcgtcggcg ggggagagcg gtctgccctg tgtcgtcgcc acgacctccg gcggatcgtc
     9541 cggggcggac tggcacagca gcccctcggc catgccgaag gactgctgca gcgagcaccc
     9601 cagcgccggc ccgaacgtcc gtgccgcctc ggcgccgaac ttcgcgccgc cgacctggac
     9661 caggcgcagg ctggacaggt cggcgggcag ggccgcggcg gcgtccttcc acagcagggc
     9721 cagcgggggc acgaggccgg tgacggtgac ccgttcgcgc tcgatgagcg ggaaggtgtc
     9781 gtcgatgctc ggtgtgggag cgaggaccac cttgccgccc acgtgcaggg tgcccagcgc
     9841 gccggggcag cccagggcgt agttgtgcgc cacgggcagc accgccaggt acgcgtcgcc
     9901 ggggccgagc cgggcgttct ccgcggtgat gcgcaggttg tagacgtagt cctggtgcgt
     9961 gcgcggaatg agtttgggca gcccggtggt ccctcccgac agcaggaaca gcgccacgtc
    10021 gccggggtcc gggggaggca ggggaaccgg atccgcgtcg gcgtccccca gggccgtgaa
    10081 ctcctcggcg tccccggcca ccagcacccg ttcgcgtccg acccctccga cccgccgcgc
    10141 cagggcccgg tggtcctcgc cgagatagcg gtccggaacc accagccagg aggcggcgga
    10201 cgcctccagc agatggcgca gttcgctctc gcggtgcgcg ggcagcgcga acaccggcag
    10261 tgcgccgagc cggaagagag ccaggcacag caccacgagc tccggcacgt tgggaagctg
    10321 caccaccacc cgctcccgcg gggccatccc ccgggcggcc agcccggcgg ccagccggtc
    10381 cgcgcgccgg tccagttcgg cgtaggacca ccgtgccccg ccgccgacca gcgcgatgcg
    10441 cgccggatcg cgccgtgccc acgggcgcac caggtccccc agcaactcac cgcgccagtg
    10501 gcccgcctcc cggtaccggt gcgcgaactc atcgggccag ggcacacatc ccttcagcat
    10561 cacggcctcc cttccccgga cacccgggcc tccagccagt cggtcagcgg tttgagtccg
    10621 gaccagccct tcctcaccag gtccagcgcc tccgggccgt gcagttcggt cggcggatgc
    10681 agccgctccg cgccgagcga gcggtaccgc agcagctcca gccgggggtg gtcggcgggg
    10741 aaaccgcggg gcctcgtcct gagccgttcg cccaccaggc tccagccgtt ccgctccagc
    10801 ttccgcacga tccgctccag ctccgggccg tgccgctcgt cgtccaccgc gtcccggtag
    10861 cggccgagct gctcggtgcc gccgtggaac ccggcgccca gccgcagccc ctccgcggac
    10921 aactgcgcgt agtacccgac gctgtccgcc gagccggcgg tgatcccctg gtaggtcttg
    10981 tacggtgact tgtcgttcga gaagcggacg tcgcgctggg gccgccacac cttcacgggg
    11041 ccgtaccgct cctcgagcgc ctcggccagg gcctccacgg gcgtgcgcac acacgtgtcg
    11101 tagacgtcct tgaggctgtg ccagtactcc ttcgagttgt ccttctccag accggcgtag
    11161 aactcgaacg cgcggtcggg gaaaccctgg aacttcacat cgtctcctcg ggcgggtgct
    11221 tcacagcgat tcggcgaacc gggccaggac atcggcggtc tgcccgggat tgagccgagg
    11281 gtcgcaagcg ctggtgtagc gggggaaggc gacacgcaag gccgggacgg gcgtgtggtc
    11341 cggtgcggag acgcactcgg tgacgtcctc gggggtcgtc tccagatgca gtccggcggg
    11401 ccactgtcgg tgggcgcgca cgatccgggc gaacaccgag acctcgtccc gcaccgcctc
    11461 cacgggccgg gtcttccgcc cagagcgcag ccgccaggtg ttgccgtgca ggggatcgca
    11521 cagccacacc accggtgcgc cccggagtgc cacctcggcg accaggccgg gcagcagcct
    11581 gcgcgcggga ccggcgccca ggcggacgat gaacagcagt ttcccctcca cgcccgccgg
    11641 gttgaggacg tggctgagcc gtacggcctc ggccggggtg atcgagggcc cgagcttgac
    11701 gccgacggga ttgcccagtc ccgccgccca ctccacgtgc cagccgtcca gagcccgggt
    11761 ccggtcaccg atccacaccg agtgcgccga ggaggcgtgg accccgtcgg ctcctcggcg
    11821 ctccaggggg gactcgtagg cgcacagcag cccttcgtgc gagacgtaca gccgcctgcc
    11881 cgccggccgg ccgggccagg tggcgcgcac ccggccgaga acggcggcgg catgatcgta
    11941 cgcggcgagc agccgccgcg gatcgcagga gcgggccggc ggctcggcct cgggcccgtt
    12001 cacggcgtcg ccccggtaga cgggcagccg tacgccgtcc gcgcgggtct cggactcggc
    12061 ggagcggggc ttggcgtact ggcccgccat ccggcccagc ggcaccaccg gcagcccgga
    12121 cgccgtgctc atcgcgtcgg ccagtgagta gaggtactcc gcgcgccggt cgacggcggc
    12181 cggcgccgcg tccgcgaacc gctcggcgca gtcaccggcc tgcagcacca gtgcctcacc
    12241 gcgcgaggca cgcgccagag cgtcccgcag cgccgtgtac tcgccctcgg tgaccagacc
    12301 ggggcgggcg gccaactcgg cttccacctg agcgagttcg tctccatcgg gccacggcgg
    12361 ctgctgccgt gccctcctga ccccggccgg tgccgtgggg gtcacggcgc tatccactgc
    12421 cgcgaccagc cgctgtcggt gagctggtag cgcagtcggt cgggtacgtg gtccgctcgg
    12481 tcctgccaga actcgacgct ttcggggacc aggcggaaac caccccactc ctcgggccgc
    12541 ggcacctcct gacccgcgaa ccgctcggcg gcggacgcga cggcgtcccg caccgccccg
    12601 gagccggaca ccacggcctg ctggtcggtg gcccaggcca ggagctgcac ggggcgcggc
    12661 agccgggtgt agtggtcgtc gcaggccagt gggtcaaggc gctccaccgg tcccgccgca
    12721 cggacctggc ggcccagatc gagccagccg aagcacagtt gcgcccacgg gttcaccgcc
    12781 aggtccaggg ccttgcggct gcggtggccg gtgaagaaga cgaatccgtg gtcggtgcgg
    12841 gcgagatcga cgaaacgcgc cgtcggcctg ccctcggcgt ccgccgtcgc cagaaccgcg
    12901 gcggccgcgt cgtagggacg tgtccgggcc cactcccggt gccagtcgcg gaaccggacc
    12961 agcggatcgc ccaccgcgtc cgcgtcgccc atgccctccc tcatcagccg gtcgcgccgc
    13021 ttttccgtac cctcctggac gggatttccc tcccggatcc tttccactct caacgtgaca
    13081 tcccttcttg cgtatgcttc cttcggaaaa gaaagaggag gaagactgtg gaaacgcgtg
    13141 atcgtgaacg agtaatccgc ctcagggaac gccaccggga gatcaccgag ccccggacat
    13201 tccgtctcgg tggccacgaa tgggacctcc ttcctggcgt gtacgccccg aatctgacac
    13261 cgtccgccct gctctacgcg gaatgggtcc cctatcccgt cggcggttcc ttctgcgaga
    13321 tcggcagcgg caccggatat atagcggtga ccgccgccca ccggggatgt gaccgtgtga
    13381 ccgcgatcga catcggcccg gtatccgccg agaacactcg gaagaacgcc gagcggcacg
    13441 gggtttccga ccgggtcacc gtgctgtgcg gcgacatgtt cgagccgctc accgagaacg
    13501 accgctatga cgtggtcttc tggaattcta atttcgtgga ggcctccttc ggggatccgg
    13561 cggccccgga ggggccggag gcggaccggg acgccatgct cgacctggcg ttctgcgatc
    13621 ccggttacgc cacgcaccgg aagttcttcg acggggtccg tgatcacctc aatcccggcg
    13681 gaagagtgct gctgggcttc accgacctcg gcgacgacga gctgctggag cgggtggccc
    13741 gggagcacgg atggtcgccg gtgccgcgcc gccgtgccgt cggcgtctac cccgacgggg
    13801 agctgcggta cgaactgctc gaactcctcc ccgtctgacg tccggcgggt ccgccgctcc
    13861 ctcccggccc ggcgagccgg tgcccggggg agcggcgggg ggcggccgcg ccgtcatctc
    13921 ctgccgagcc gtaccgccag cggcgccagc acggcggtgg ccgcgacgac ccaggccagc
    13981 gtctgcagca cgggcaccag caccgggccg cccgaggaca gtcccatcag cgcgccgtgg
    14041 gcgcacgaca gcgggttcgc gcgcaccacc ggctgcacga acccggggaa cgcctcggcc
    14101 ggcaccagcg tcgtcgacag cagcagcagg agcgtgaccg gggcgttcag cagccccgag
    14161 gccgtctcct gactgccggc cgacagagcg gtcaccaccg cgagccacag gaagatcgag
    14221 gcgaacgcca ccaccacgag caggaagccc accgcggcca ccgcgccgcg ttcgaaacgg
    14281 aaaccgagca ggcagcccac cagtaccgtg accgccgtca ccaggacgaa cttgaccaga
    14341 tcgccggtga tgcggcccag cagccccgcg gagcgtccga tgggcagagt gcgcagccgg
    14401 tcctggaagc cgccgcgcag gtcgccgtag aacccgaccg ccgtcccggt gcagctgtac
    14461 gccacgctga acagggcgat ccccggggtc agtcgggcga tgtagggctc gtccccggcg
    14521 ccgccgacca cctcctggaa catcacgtac agcgccacca gcaggatcag ggggaacgcc
    14581 agcgcatcgc ccagcagttg cgggctgcgc aggaaccgcc tgatgttgcg cccggcgagc
    14641 accgacgctt cgaacacgac cgtcatcgcg ccctcccgaa tgccttggtg gacgcccacg
    14701 cgccgacggc cagcagaccg gcgatccagg ccagggccgg ccacacctcc ccggccgacg
    14761 gcgacgcgga cgccagtgag cgaagggcgt cgatgaccga agagaccggt gacgcctcga
    14821 cggcgggctc cagccagtcc gggaaggccg aggcgggcac gaaggccgtc gacagcagga
    14881 tcaggaccag atacggcagg ttcagcgtcg ccgacgccgc ctcgggaccc gccgacacca
    14941 ggccgacggc cgtggtggcc gccgtcaggg tcagggcgaa cgcgacggcc agtgcgacga
    15001 agccggcgac cgcgaggacc gggccctgga agcggaagcc cgccagatgg cccgccgcgc
    15061 cgatgaccac gacggccacc agcgcccaga cgacgtccga gaccagccgc cccgcgacga
    15121 acgcgccccg gttgaggggc atccaccggc accgggacag catccccgag tcccggtcgg
    15181 aggcggtggc cacccccgag gtgttggcca cggtgaacat ccactggacg acgatcgcgg
    15241 gggtgaggaa ctgggcgtag tccagccccc gctcctcgaa gatcctgccg aagagcatca
    15301 ggaaaccgaa gacgaagacc agcgggaaga ccgtgtagac caccaccgac tgcgcgttcg
    15361 cgccgcgccg caggttccgt gccgccagca ccaggccctg tgcggcgagg ttgccggcgc
    15421 cgcgttcggt cgacgccccg gcacgggggc gttccgtcgt cgttgtcatg tacggctttc
    15481 ctccggaggg ccgggggcgg cctcggggtc ggtgagggcg aagaacacct cgttcagact
    15541 cggcttgcgg agagtgacgt tctccgggtc cacgccctcg tgctccagga ggccgagcac
    15601 ctgcgccacc accgaggtgc gaggcgcagg taccaccagg gtgccgttcc tccccgacac
    15661 ctcccccagg gccctccgca gcgccgccgc ggcctcgtcg tgccgttccg gagccacctt
    15721 cacctcgcag acccggccgc cgacccggtc cttgagctcg ccgggtgtgc cctcggccgt
    15781 gacccgcccc gatccgagca ccaccacccg gtccgccagc cggtcggcct cctccaggta
    15841 ctgggtggtc agcagtgtcg tggtgccccc tcgccggagt tcctccacga cgctccacac
    15901 ctcctcgcgg ctgcgggggt cgagcccggt cgtgggctcg tcgaggaaga ggacggggcg
    15961 gtcgacgacg aggccggccg ccaggtccag ccgcctgcgc atgccgccgg agtactcctt
    16021 gaccggccgg ccgccggcgt ccgacagacg gaaccgctcc aggagttcgt cggcccgcct
    16081 ggcggcgttc cgggcgccga gccgcagcag gcgcccgaag aggaccaggt tctcccgccc
    16141 ggtcagcatc tcgtccagtg cggcgaactg gccggtgagc gcgatggaac ggcgcacctc
    16201 ctccggctcg gccaccacat cgtgccccgc cacccgcgcg tgcccgccgt cggggcggag
    16261 cagggtggtc aggcagtcga tggtggtggt cttccccgca ccgttgtgcc ccagcagacc
    16321 gagcagggtg cccggggcca ccgagaacgt cacatcctcc agcgcggtct tctccccgta
    16381 gcgtttgcgg agtccctcga cctcgattcc ggccccaggc aatcgttttc ctcccgcccg
    16441 tcggtcattt ccctcgcgag tccgccggcc tcctcacccc tcctgctggg aggcgggggt
    16501 ctgctgatgg aacatcagct tccagccttc ttcccggcgt acccagacgc tcgacatgta
    16561 caacctgaag gtgccccttc cggtgacgtc ggcggtggcc cggtaggtga cgacggcgga
    16621 gtccggcgac agcgggacga ggcggcggtc atccagcctg aagttctcga acggcgactc
    16681 gttgccgtcg atctcggcca ccagatcgtc gcccgtggcc actccgtcgt gctcgaccac
    16741 gagtgtttcc ggggtgacga gtcgccggta gaagtcgccg ttcgcggagg agatggcctc
    16801 ccagcccgct tcctccaggg cgaagagttc cttctccatg gtgattcggt cgatctcggc
    16861 catttgttgt ccgattcctt tcctgtccgc ttctgtcttt cttctgctca ttgttccccc
    16921 cggcccttcg ccgtctccac cgactcgcgg cggtcgcggc accgttctca gggggtggac
    16981 ggccactcca gacccgccgg ggctccgcgg ccgagatccg ccagtacggc tcccagcacc
    17041 gccacagggc gctccagcag gtagaagtgg cccccgggga agacgtgcag acggaacggg
    17101 cccgacgagc aggaccgcca cgcctccgcc tcctcgggag tcacctcggg gtcgctgtcc
    17161 ccggtcagcg cggtgatcgg ggtgcgcagc cggcggccct ccggcggccg gtaggtctcg
    17221 atcagccggt agtccgcccg cagcgacggc aggacgagac tctgcagcgc cgggtccgag
    17281 aacagcgcct cgtccgtgcc gccgagtcgc ttcagatccg ccagcagagc ttcgtcccct
    17341 ccctcgtgca ccgacacggg gtcccgggtc cccggggccg ggcgaccgga gacgaacagc
    17401 cgcagcagag aacttccggt gcgctcctcc agccgcgcgg cgacctccgc ggcgaccgcc
    17461 gcccccatgc tgtgccccag cagcaccaga ccgtccccgg agacgggggc cagggccgcg
    17521 gcgagggggc ccgccagctc gtccatacgg gtcgcgcacg gctccccggt acggtcgtgg
    17581 cgcccgggat actgcaccgc cagcaggtcg acgccgccgg ggagcagcgg cgcgaagggc
    17641 cggaaggagc ccgcggcgcc ccccgcgtgg gggaagcaga ccagcctgat ccgctgtcct
    17701 cccccggagc cggggccctg tccgcccagc gggcgcagcc agcgccgccg ctcctcctcg
    17761 cccctgcccg ggccggtgac gatccgcgtc gtccggttca ggtgcatcgc ggtacctcca
    17821 gttccccggc cagttccccg gcgccgatcg gcctcacggc cgtcgcgtcg gtcagttccg
    17881 gcgggcccag ccgcacggcg gcgtcccgcc aggcgtgcga gacggcgagt tgggcgtgcc
    17941 cctcggccag cggatggtgc ccctcgcgca cggcctcgtg cagttccgtc agcgcgcgca
    18001 gcgcggcgtc cggccacagc ctccccacga cctcccggta gctgggggcc gcggcatcgc
    18061 ccagcggggt ggtcgcggca tggtcgaggt ggccggacgc cgcctcctcc agccgcgtca
    18121 gcgaccgctc ctcggacggg aagtgggggc gcgggctcca cagcagcggc ccgtgggtgt
    18181 cggacaacgt cagactgccg ccgtccgtgc cgagtgtgat ccggtgcagc agatgggcgt
    18241 ggttgtccgg atccgacggg ttcaactggt tctgcacgcg cagggtcagc ggtacgtcgc
    18301 gcaccgtccc ggtcagggtg tggaacaccg gagtgggccg cgcgtcctcg aaggaccacg
    18361 gccgcagccc gcccagggcc agccgcagga tgtcgaacag gtggtagaag acctggagtc
    18421 cgcaggccgc gtcggcgtag agcaccggcc ggcgggcggt gagcctgcgg gccgcggcga
    18481 tgaacctccg caccggctcg acccgcacgt agtgggtgct gacccggaac accacccccg
    18541 cccggcgcgc cacgcgcagc gactccgcca actcgtcgtg gtgcagcggc ccttcctgca
    18601 ggacgtggac gccccgctcc atcagctgcc gggccagctc gcttccgggc ccgccgttca
    18661 ccccggcgta caccgcgacc acggcgatgt cggtgtcggc cggcaactgc ccgggatcgg
    18721 tgtacagggg cacgtccgcg cgttcggcgc aggcccgcga ccgctcgctg ccgcgggcga
    18781 ggacaccggt cagccgcagg tccccggctc cccgcggcgc gtccgggccg ccggcctcca
    18841 gcgcgcgcag gtagacccgg ccgaacccgg tcccgcagac caccacgttc gccgtcacag
    18901 cactccctcc tccaccggtg gggcgtcctc ttcctccacc ggcggggcgt cctcgacgat
    18961 ccgcaggtgg ccgacccccg gcatggcggc cagccggtcc ggtgccgtgc gggcgtcgac
    19021 ggcctcgtcc gccggaagcg gaccgggcgc cacctccccc gccagcacac accggacggc
    19081 gaacgcggtg aacgcggcgg tgagcgcgta actgtcgtcg gcccgcagca ccagggtccg
    19141 gcggtgaggg cggccgtcgc gctccccctc cagccggaag accatgagct ggtacggcgt
    19201 gcggccgaac aggtccagtt ccgcggcacg gaccagtcgc ccggccgcct cccgcaggtc
    19261 tccgtccgag ggggaggaca gcgcgcgcag cgcgtgtccg ccgtcgaaga cgttgtacca
    19321 gtgggcctcg gccagcccca gatcccgggc cagccgctcc gtctcggcgc tgaggaacgg
    19381 gtacgccgtg acgggcccgg ggaagaaggg cagctccgcg ccggtgaggg gggtcagggc
    19441 gccgggcacc cggcacccgc cggaccacgc gctgagggag cgcccgccgc cgtcccgggc
    19501 gccggccacg tagtcctgtg ccgatgccca ggtgaagcgg tcccggccgc cggcgtacgc
    19561 gaccagccgc tccggccggc cgaggccggc ggccagcgcg cggggcagca gtgccgagag
    19621 accgggcgcc atccccgcgc ccagcaccgc gcacagccct ccgtccggat ccccgaactc
    19681 cccggacccc ggcccgtcga gcagttcccc gcccgacgcg cccacgtagt gcgcgccccc
    19741 ggccagcgcg gcgcgcagca cccggggcgc cgtgcgccgg gcgggtcccg tgcagtccac
    19801 gaccacgtcg cacctcctgg cgaaccgttc caggccatgc gggtcgtcca cgtcgaccac
    19861 cacccgctcg tggccgggcg accggtccag ccgcgcccgg tcgcggccgc ccagcagcac
    19921 ccgggcgcca ccgtccacca gcaggggggc gacatgtctt ccgacagcac caccggagcc
    19981 gagcagaccg agcacggcgg tcaccggcca cctccccggt gcagccggtc cagctcgcgc
    20041 gcgacacggc cgacgtgcgg cgggcgcata caggagaagt ggtcgccggg tacgtcgacg
    20101 atctcgaggt cgcccaggca cagttcccgc cagaactccg tcatgtccgc ccgcagccag
    20161 ggcaggaagc cggtcgcctc gtcctcgcgc agcaggacga catcgcccgc gtacggcgtg
    20221 gcccggtgcc gggtgaccgc cgtcatactc gtgcggtaca gggagtagac cgcctccagg
    20281 tccaccggga agccgtcacc gtcaccgtcg ccgtcaccgc gtgccgcgcg gccgatcgcg
    20341 gcgagccgct cccgctgcgg caccttccgc agcgcggcga acctgcgtgc cgcctcctcc
    20401 accacggggt ccccggtcag ggagtccggg gacccggagg gcacccggcc gggcgtgtgc
    20461 tccagcaccg cccggaagac gtgcgcggtc gcggtgtcgt cggggtaacc gagctcctcg
    20521 gtgtcggcgt tcagcagccg tgcgaagacg tactccagca ccagttcgtc ctcgacggtg
    20581 tgaggcagtg cgtaactgct cacgatggtc aggttctcca ccagcgcccc cgactcggcc
    20641 agctgccggg cgacctccgt ggccagcagc ccgcccatgc agtagccgac gacctggaag
    20701 cgggtgtgcc cggtctccag caggcagcgc gtgtagtggg ccgcacgccg cacgatgagg
    20761 tcctcggggt cctcccgcgc gtacggctcg tgcgcgggga cggcgagtcc caccagcggg
    20821 cccggcccgt ccagcagcgg tatcagcggc cggtaggcgg ccagtgtgcc catcccgtcg
    20881 tggaccagca cgcgcatcgc cgcgccctcg gctccctccg gcccctccgc gccggacccg
    20941 gagggaccgg cgccgccgag cgggaccagc ggcgagtcgg ccgggccgtc cccgccggtg
    21001 ccttccgtgt gctcgcggga gtcgcgcagg aactccgcca gggcggccac cgtcggacgg
    21061 ctcagcacgg cgcgcagcac cgtgtcgtac agcagcccgg ccgcctcggg gatctcctcg
    21121 cggacacgcc ccgccagccg cgccaccagc agtgagtccc cgcccagccg gtagaagtcg
    21181 tcgtcgcgtc ccacccgggg cagccgcagc aggtctgccc acacggcggc cacgcgccgc
    21241 tccagatcgt ccaggtgctc cgttccgccg ggcagtccgg ggtcgtcggg ggcgcggtgc
    21301 cgttccgccc agccgcgcag caccgcggtg tcggtcttgc cgttggcggt cagcggcagg
    21361 tcgtcgagga gttcgagccg cgcgggcagc atgtactccg ggacgcgccg ggcggcgtgc
    21421 tccagcacgt cctcggggcg cacgggtatc cggtccgcct tgaagcgggc cgcgaagacg
    21481 cgctgcccca gcggtgccgt cacgccgtcg gcgtgcggca gttccaggac ggtgtccgcg
    21541 ccggcctccc ggagcaggcg ccgccactgc ccggagtcga ggaaggtctg gtcccgcccc
    21601 cggcgcaggt cctcgtagtc ccacttggcc ggatccctgt cgggcatcat gaactccatc
    21661 gaggtcatga tctgcacgtt ctcctgcgtg gtctcgatga agaccagcca ccccccggga
    21721 gccagcagtt cgcgcagccg cgccaggacg gtgtccacgt gccgggcgtt gtgcaggacg
    21781 ttggcgcaca gcaccacgtc ctgcgagttc gggagccggc cctgctcccg cgcgtcgccg
    21841 ttgatgtcga acaggccgta gtcgacgcgg tcgccgaaac gtcggcgggc ctcgcccagg
    21901 aagaactgcg acacgtcggt gaacaggtag cgcacatcgg tgtcggcgat ctccgggacg
    21961 agtacggtgc tggtcccgcc gacgcccgcg cccacctcca gcagccgcag tggcccctcg
    22021 tgcgccgcgg ccagctcgcg gaccagcccg acgacggcgt ggttgacgta gcggctgagg
    22081 acgttgtcgc ggtaggcggc gtaggagagg tccagtcctc cctcggggaa gagcagcggc
    22141 agcggatcga tctcgtcgcg cagcagttcg ggcagtcgct cggcgcaggt gcggaagtag
    22201 ccgatgaggt cggccctgta ccactcctca cgctggagcg cgtccacctc gcgccatgcc
    22261 gcgtccagat cctccccgga gacgggcccg gccgccgcgt aggcgtcgcc gtggcgggtg
    22321 agcaggcccg cctcggtgag ggacttcagc cagcggcgca ccagccggtg gtggcagggt
    22381 gccgccgccg tcgcctccag cacctcgggc acggtgtggc ggtcgccggg cgaccggaac
    22441 aggccctgcc ggttgaaggc gtgcagcatg gccagcagcc cggcccggtc cagccgccgc
    22501 atgaactccg acagctcggc ggggtcgacg tcccggaccg cggcgtcccc gcgggccgag
    22561 gccgccgcca ggagccgctc ggcgccgcag tccggcaccg accgcgcccc ggtggccagc
    22621 cgggcgtacg ccagcaggcg gcgatccagc ggcccgtcgc cgtcgaccag cgcgtgggcc
    22681 gacgccacgg ccgggtggga ggagagggcc gcctcggtct cggccagctc gatccggtgg
    22741 ccacggatct tgacctggcg gtcctgccgg ccgaggaact cgatgacgcc gtcctctctg
    22801 tacacccccc tgtccccggt gcggtacagc cgctcaccgg tgcgggggtg gtacacgaac
    22861 cgctcggcgg tcctcgccgc gtcgccgagg taccccaggg cgaggccggc cccgccgatg
    22921 tacagctcac cgggcacgtg ctccgggcag gaccgcagcc acgggtccag gacgtggaag
    22981 gtctggttgg tcagcggcct gccgtacggg atgctgcgcc agtccggatc cacctcgccg
    23041 atggggtggg cgatggacca cacggccgcc tcggtcgcgc cgccgagact caccagccgc
    23101 aggccgggca ggcggcggcg cacccggtcg ggcagggcca cggggatcca gtcgccgctg
    23161 agcagggcca gccgcagcgc gtccagaccg gcggcgggct cgacggcgag gtagtcctcc
    23221 agcaactgga gctgggcggg gacggagttc cacacggtca cccggtgctc ggcgagcagc
    23281 tgcgcccagt gcgaggggtc ggcgcgccgc tccgggtcgg gcagcacgag ggtgccgccg
    23341 gcgcccagca cgccgaacac gtcgtacacc gacaggtcga agcccatgcc cgccaggccg
    23401 agcacgcggt cctccgcggt gacgtcgaac cgccggctga cgtcccgcag cgtgttgagg
    23461 gccgcccggt gcgagaccat cacacccttg ggcgcaccgg tcgagccgga ggtgtagacg
    23521 acgtacgcca ggtcgtccgg gccggcgggc ggggccccgg cgcttttgcc gcccccttcg
    23581 cggacggcga gcgcgtccac cgcgacggcg tgccgaccgc agtcgtcccc cggcagggac
    23641 cacgactgga ccagcacgtg gcggactccg gcatcgtcga ggatccgctc gcggcgcagc
    23701 cgcggctggg aggcgtcgag cggcaggtag gcgcagccgg ccagcagggt ccccagggcc
    23761 ccggccacct gttcccagcc cttgtccatg accaggccga ccacctcacc gggcgtgcac
    23821 ccggcctcct gcagccgtgc ggccaccgcc tccgcccggc cgagcagctc gccgtggctc
    23881 agggtccgcc cgctggagac gaccgccggc cggtcggggt gcgcccgcgc ggcggtcacc
    23941 aggtcgtcgt ggagcagcgc gtccggcaag ggggccgcgg tgtcgttcgc cgcgtcccgg
    24001 cgacgctgct gagcccgcgg cagcgggacc ggggagggct cctcccagac ggccgcgtcc
    24061 ttgcccagcc ggcgcagcag tgccaccagc acgtcgaaca tctcctcggc cacgcccggg
    24121 agcaggactc cctcgcgcac gtcccagcgc aggtccaggc agccgtccga ctccaccgcc
    24181 tgcgcgtcga tccacacctg cggcgtctgg ctgatcccgt ggacggggcg ctccgccggg
    24241 tcgtcctgcg cggcggcctc cccggggccg ccggcgtccc cggcggtccc gagggtgctg
    24301 gtgaagacca cgggcagcag cgccgcggcg gatccgcgcc gccgcgccat ctcccgcatc
    24361 acctccaccc cgctgtagag ccggtggtcc atgtcctccc acatccgctg ctgcagggcg
    24421 cgggcgcgct ccccgaacgc cgagaggggg gcggtgtcca ccgccagcgg gctgacggtg
    24481 gtgaagtcgc cgacgagccg gtccacctgc gggtgcagcg gctcccggtt gagcagggtg
    24541 aggttgaggc agaaccgcgg cttcgcgctc caccggccga tcacctccgc gagcgcggcc
    24601 agtaccgccg cggacggtgt gaggttccac cgggcggagg cccggcggac cgcctgccac
    24661 tgctccgggg agagggtcga ggacagccgg cggaagcgcc cgggcaggta ctcggccccc
    24721 tcgcgcacgg ggagttccgg ggcggcgggc agctcgtcca gccgacgtgc ccagtactgg
    24781 cggtcacgct cgtgggcggg gctctcccgg cggcgcgcgg ccgcgctcag gtagtcgcgg
    24841 aaggtgatgt cgagcggggg cggcgtcaga ccgtcgtaga gcatccgcag ctcgcgcatc
    24901 agcgtccgca cgctcaggta gtccgcgatc aggaagtcga ccgacacgtg cagcaccgcg
    24961 caggcgtcgg taagggtcac gcgcagcgcg aacagcggcc accgctcggg gtcgtggacg
    25021 ctgtggtcca tcgcggcacg cacctcggcc cgggccctgt cggcctccgc gggggaggcg
    25081 ccgcgtacgt ccgtcacctc gatccggtag tcgggcacct ccgggagcac ccgctggtgg
    25141 ccgtccaggg agatcacggc gcgcagcatg tcgtgccggc cgacgagccg gttccaggcc
    25201 gactccagcc gtgcgggatc gagctcggcg tactccatct ccgcgtagac ctggcagccc
    25261 acccctccgt aggcgaaggc ctcgcgccgg cccagcaggt acgcggactg cacgtcggtg
    25321 agggggaacg ggtcgtaccg gtgctcggga tcgcggacga ccgccggcga ctccgcccgc
    25381 agacacgcca ggacggcctc cttgtgggcg gccagcgcct cgcgccactc gtcggtgagg
    25441 acgccgcggg gggccctgaa cctcagccgt cccccgtcct cccacaaccg gactccgcgt
    25501 tcgcgcagat ccgccaccag agtctccggc gtacgggcag tgtctgctga cagggtcaca
    25561 gggagccctc ctcgaagctg tcgatcagtg cggcggtctc ggcgacggtc ggtgccgaga
    25621 agagttgccg gagagtgacc tcgacgccgt ggcgctcacg cagtgcctgg gccatgcggg
    25681 tggcgatgag gctgtcgccg ccgagggaga agaagttgtc gtcccggtgg atgccggaga
    25741 tgcccagcag ttcctcccac accgccgcca cggcctcctc ggcggggccc cgcggcggct
    25801 gcgaaccgcc accggaccgc tccttggaga acaggtcggc caccgcccgc cggtcgatct
    25861 tgccgttggg ggtcagcggc atggcgtcca ggacgaggca gacctgcggg atggcgtagg
    25921 agggcagcct ctcggcgagg aagtcctcca ggtcgtcgag tgcggagtcg tccccggccg
    25981 cctccgaatc cggggtgacg gcggctgcga gttggtgtgt gtggggggtt ttgagggcgg
    26041 tggcggtggt gatgtggggg tgttgggtga gggcggtttc gatttcgccg agttcgatgc
    26101 ggtggccgtt gatcttgatt tggtggtcgg tgcggccgag gaattcgagg gtgccgtcgg
    26161 gccagtagcg tccgaggtct ccggtgcggt accagcgggt gttgtgggtg cgggggaatt
    26221 tgcggttggt ggtgtggggg tcgttgtggt agccgagggc gaggctgtgg ccgccgatcc
    26281 agagttcgcc ggggacccag tcgggtgcgt cgtgtccgtg gtggttgacg acgcggtagt
    26341 gctggttgcg cagggggcgg ccgtagggga tggaggtcca gtgcgggggg acggtggtga
    26401 tgtggtggtg gttggaccag atgccggctt cggtggcgcc gccgagggcg atgagggtgc
    26461 agtgggggag gtggtgggtg aggcgggggt ggaggtcgag ggggacccag tcgccggaga
    26521 cgagggcgag gcggagggtg tgggggaggg ggtggtcgtc ggtggtggtg gtcaggagca
    26581 tgtccagcag ggctgggacg gtgttccaga tggtggggtg gtgggtgtgg gcgaggtggt
    26641 gccagtggtc ggggtcggtg cggtggtcgt ggtgggggag gatgagggtg ccgccggcgg
    26701 tgagcaggcc gaaggtgtcg tagacggaga ggtcgaagtc cagggcggac agggccagga
    26761 cgcggtcgtc ggcggtgacg tggcagcggt cgttgaggtc ggtgatggtg ttcatggcgg
    26821 cgcggtggga gacggccacg cccttgggtt caccggtgga ccccgacgtg aagatcacat
    26881 aggccagtcc gtcggggttc ccgggcaggg gtgcgtccag cggggcggac gcggcgcagt
    26941 cggccagggg caccgccgcc ggttctccgg gtggcgcgtc catgctctcg cgcgtcagca
    27001 cggttcgtac tccggcgcgt tggtacatcc gcttgcggcg ctcgggtggc tggtcgacgc
    27061 cgacggggac gtaggcggct ccggcggcca ggacgccgag gacggcggcg atctggtccg
    27121 gtcccttggg cagggtgacg ccgaccggtt cgcccggggt ggttccgcgg tcccgcaggg
    27181 ttgcggcgat gcgcagggcc tggtcggcga ggtcgtggta ggtgacgtgg tcgtcctggg
    27241 tgagcagggc ggtgcggtgg ggggtgcggg cggcgtgggc gaagaagccg tcgtgcagga
    27301 gggtgtcggg cagtgggccg gtggtgtcgt tggcggcggc gcggacgatg cgctgctcgg
    27361 gtgggagcag tgggggcagg ggggtgttcc agtcgtggtc gccgaggtgg tcgagcagtc
    27421 gggtgtaggt ggtgaacatg gcgtccagga cgccgggcgg gaagagttcc tcgaccgcgt
    27481 cccacaccag cagcagaccg ccgtcctgct cgatcacctg gtggtccagc cacacctgcg
    27541 gcgtctgcga ga
//
