LOCUS       NZ_FOET01000006        21110 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces radiopugnans strain CGMCC 4.3519, whole genome shotgun
            sequence.
ACCESSION   NZ_FOET01000006
VERSION     NZ_FOET01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces radiopugnans
  ORGANISM  Streptomyces radiopugnans
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900110735.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:56:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,515
            CDSs (total)                      :: 5,440
            Genes (coding)                    :: 5,315
            CDSs (with protein)               :: 5,315
            Genes (RNA)                       :: 75
            rRNAs                             :: 4, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 4, 5 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 41 of 125
            Pseudo Genes (incomplete)         :: 106 of 125
            Pseudo Genes (internal stop)      :: 6 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:58:30
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 26158
            Orig. end                         :: 47268
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOET01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21110
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21110
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21110
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11110](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11110
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(480..2012)
                     /locus_tag="BMY40_RS13925"
                     /old_locus_tag="SAMN05216481_10618"
     CDS             complement(480..2012)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058724.1"
                     /locus_tag="BMY40_RS13925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10618"
                     /product="hypothetical protein"
                     /protein_id="WP_093659553.1"
                     /transl_table=11
                     /translation="MCRVTTAVSASSPGAARPAPGPAADEGLARRLRALACTAPLHDLD
                     ARKANLAGEYGTYSMAEVALAAIDLVTLHMDFDTGADHEEIVARLLPRVAAQAPRRPAA
                     EHERVARWVLENLINVGSVDRGFRAVYGTFGPDGEYVRRDYDFKLIEEVPGPGGGVYLR
                     TTDEAVNVLVGALDTDVTSAQIAAEVKLEVLVSRGRLADAQLAAEQARYRTVQYAETLR
                     RTLEATRRNVRAVDWLNAVPDMIAEALDHVADRYRHENAILTNIRRARDEAPADKNPGH
                     KLRAAELVDIVKDCIRRHTQLQSRLLEAGPLFRAEQDRQAFAPPAAGAGLDLYGQLLAP
                     VLPLPVERATKVTDAFFARGTGLRTPAAVRLGDLTEMLLTPPAPREHLGAEMPEPDLVA
                     TPDDSRFSEEQMEAARELLELPADAPRRLSGLLAEARRRDPELPYLVALLAVHAASPPV
                     GTAYRQGERRLLFAVDDGTELDDPEFGGADLVVGTALLDAAGMAADRTEVAS"
     gene            complement(2127..3683)
                     /locus_tag="BMY40_RS13930"
                     /old_locus_tag="SAMN05216481_10619"
     CDS             complement(2127..3683)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356245.1"
                     /locus_tag="BMY40_RS13930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10619"
                     /product="hypothetical protein"
                     /protein_id="WP_093659274.1"
                     /transl_table=11
                     /translation="MFADSVDSDIAPSGTLLGLLQRGRGDGTLHALAAPRAEALAALSH
                     CLRCDPRRDWRLEHRSLYYARLHVELDAGLDDIEEHLFGPDDLTDGGEERTGLALSVLG
                     HLASYGDRGALLLLRRYASRGANWRWALDELAVRDDDAGLRPLGPAVLARFPRTPEGDA
                     ELAAAVRDAFEPRPWRLWAEDPARPEQGERLGRAREQGSFGRWQRQMRPAGPRPGWSVR
                     AVLDWAQEGDPLLSTAHPAADGPLASASAGSAVPMAAPGPDPRHREAAAARCLTAVAGP
                     DDRPELLDAARSGPDIARAVALRHLAERGDPAALDLIEAAAGDPAADPAGLAGGPSGTV
                     ARAALDALSRTRGTAALERARRWARREDPLGTAAATLLACHGAERDAPLVLAALRRTVR
                     AEGPDSDALWPLVDGAGRLAVHRAAPLLRHVYRETASSQLRGRAARALAATDPAFAAGF
                     AIECLWDCEESTREIAARHAATGDTRVVERLRRLAADPAEEEGVQSAVRGRLGSGGAAA
                     R"
     misc_feature    3677..3690
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.54"
                     /tool="antismash"
     misc_feature    complement(3725..3742)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            complement(3948..5456)
                     /locus_tag="BMY40_RS13935"
                     /old_locus_tag="SAMN05216481_10620"
     CDS             complement(3948..5456)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144554.1"
                     /locus_tag="BMY40_RS13935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10620"
                     /product="hypothetical protein"
                     /protein_id="WP_107436769.1"
                     /transl_table=11
                     /translation="MTKGPNTRLADLFGLTGWSKGELARRVNRQAAAMGHPQLATDTSR
                     VRRWIDMGETPRDPVPKVLATLFTERLGRVVTIEDLGFSRSGQTGRRQSVHGLPWAPEQ
                     TAAVLTEFTGMDLMLNRRGLVGAGAALTAGPALSSALYDWLRTDPAPAGAPRPGGSALA
                     APASSDRYEAAPVGVEEVESLEHSVEVFRAWDAARGGGLQRKAVVGQLNEVGGMLAYRH
                     PPHIQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRAGEAVSRA
                     ARQMVHLGRPDEALDLMKLAKAGCGEETLPRTRAMLHTIEAWAHASMGRGQAMRRTLGR
                     AEDLFVSDRGDVPPPSWMQLFDEADLHGMQALAYRTLAEHDPSAARTAEKHAKEALRLR
                     EKGRERSKILDYISLASACFIADDPEQADRYARLALVTIGNTSSHRTWDRLREMYRLTG
                     RYAGYPKVEDLREEIALALPAAPGFSGATAAVPAPRRAGGGAAV"
     gene            5702..6826
                     /locus_tag="BMY40_RS13940"
                     /old_locus_tag="SAMN05216481_10621"
     CDS             5702..6826
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959298.1"
                     /locus_tag="BMY40_RS13940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10621"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_093659276.1"
                     /sec_met_domain="APH (E-value: 2.4e-14, bitscore: 47.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPTPSPVPAPVRPRPRPQYGTVLPEPVRTPPAVAGLPRPRRAPG
                     AGVLPAAGRPEPSGPRDGRLRTAIASVHRVCPEFQPVQVLRRGGRSVLLAGTVGRGGAV
                     AKCLLDHSPARVERFRHEIAVYRAFVRQRPPVRVPRLIAADPDGCVLVAERAPGRPMAL
                     QRHPLELPSPADLRAVLGAVCRVNAWQPPAGLFGAPVDYGVRIARYHGLGLLTDRDLGD
                     LRKLLHGLARGGGRAQFCHGDALPVNVLLSPAGPVLLDWEHAGWYLPGYDLATLWSVLG
                     DSPMARRRISRLAQAGGRDARDAFLVNLMLVLTREVRACETAVQRAMRDPGPAPGSDRT
                     GLLSTGEEQRLLLRRLHDDCAMVRRAVRAAVGTR"
     gene            7210..9120
                     /locus_tag="BMY40_RS13945"
                     /old_locus_tag="SAMN05216481_10622"
     CDS             7210..9120
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058742.1"
                     /locus_tag="BMY40_RS13945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10622"
                     /product="peptidoglycan recognition family protein"
                     /protein_id="WP_245770094.1"
                     /transl_table=11
                     /translation="MLLPLLPATADAGGREPDSLQEAFARAADRYQVPESVLLGVSYLQ
                     SRWDGHRGAPSVSGGYGPMHLTDARTALAEDPHHSHGTEDARGDTARAVRQVHDAVPDP
                     AALPARLRTLERAAELTGLDEEELRRDPAANVAGGAALLAAAQKELGLPLSDDPAQWYG
                     AVARYPGSGDARAAGVFADEVFDVLREGERRTTDSGQRVVLEGAPDLAPDTAQLDGPDL
                     RPASSGSDGPVECPRSVSCEWLPAPYEEYTNPDGSPNYGNHDKADRPASQKIDYIVVHD
                     TEATWDTTLRLVRNPKYVSWHYSLRASDGHIAQHVPTRDVGWHAGNWYVNAKSIGLEHE
                     GFLTAPDAWYTEAMYRTSARLVRYLAHRHGIPLDRQHIIGHDNVPGVTSANIPGMHTDP
                     GPYWDWQHYFTLLGAPFHPTAAPDSELVTIRPDYEEHRPVYTRCDGSGQPCPPHGSGAV
                     RLHTGPSADAPLVKDAGLRPGGGDSTTGVNDTGARASTGQRYAVAERRGEWTAIWYLGQ
                     KAWFHNPADAPTAVGSRGLVVTPREGVESVPVYGRAYPEASAYPEGIPAQAISPLPYKV
                     EAGQAYALGLRTKGEYYYAKTFDPAGHVVVRGEEEYYQIQLGHRVAFVKAADVTVRPAR
                     R"
     gene            complement(9217..9714)
                     /locus_tag="BMY40_RS13950"
                     /old_locus_tag="SAMN05216481_10623"
     CDS             complement(9217..9714)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356240.1"
                     /locus_tag="BMY40_RS13950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10623"
                     /product="hypothetical protein"
                     /protein_id="WP_093659278.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLFGGRGPAMVIGNLPEGSPARETAEGQIPFEVAQLLAALENDEEVTVTGTEES
                     PVMLDDNLLIVRRILCSETRISCVQFDRSDGVLVTIASWDRPITEDLYQLLKPLPAELF
                     QR"
     gene            10001..11110
                     /locus_tag="BMY40_RS13955"
                     /old_locus_tag="SAMN05216481_10624"
     CDS             10001..11110
                     /EC_number="4.2.3.157"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713273.1"
                     /locus_tag="BMY40_RS13955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10624"
                     /product="isoafricanol synthase"
                     /protein_id="WP_245770080.1"
                     /sec_met_domain="T1TS (E-value: 2.9e-77, bitscore: 254.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEVGAVGDTAGREGLLRRTARLEIPFRSAVGPGVGKARLHTLRW
                     LRDFGLLTGEAAFEEYDALRLERAMARFYPRAAEEDLMLATDVNGWFFVFDDQFDGPLG
                     RRPRDVTRLVDRLVRVMDGREPPAGAPAGPLVESFRDLWHRINEGMPPVWRERFRRHWH
                     GYLLAHRREALNRSGDRLPTVEEFLAARRHTIGIQPCLDLAERFGRYTLPSALHGGHPL
                     KEMRRITDEVAIFVNDIVSLDKELAVGDVNNTVVLLRHGTGRPLPDCVREIRAAANGRV
                     ARFRELAAGLPALLGAAGVPGEARAHVEDYVDGMRNVMRGNLDWSLESRRYDDAGVAAV
                     SGGRLRPWAGLPDEAVPERGVGAAGPVRP"
     gene            11107..11847
                     /locus_tag="BMY40_RS13960"
                     /old_locus_tag="SAMN05216481_10625"
     CDS             11107..11847
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639385.1"
                     /locus_tag="BMY40_RS13960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10625"
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="WP_245770081.1"
                     /transl_table=11
                     /translation="MRRETDGGTTVNLWRAGLTRVPEQVWEHRESRVLILADNALTSLP
                     PRIGRMRRLRTLDLGHNALTSLPEEIGELTDLDGCLYLHDNRLTALPRSLGRLRSLTYL
                     NVGDNPLGTLPEEVGDMAGLVELRAQRCGLRELPASLGRLTALRELWLRGNALASLPAA
                     VRGLRELRELELRENALAQVPEALRGLPRLRRLDLRANRLRTVPDWLERELPALEKLDL
                     RWNEAAVEPKLLEALERRGCVVLR"
     misc_feature    complement(11920..11931)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 14.73"
                     /tool="antismash"
     gene            11970..13832
                     /locus_tag="BMY40_RS13965"
                     /old_locus_tag="SAMN05216481_10626"
     CDS             11970..13832
                     /EC_number="3.1.1.103"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956464.1"
                     /locus_tag="BMY40_RS13965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10626"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_093659282.1"
                     /transl_table=11
                     /translation="MTGSARDRAPGRAPASGPAASEGIGRRQLGLRALALGGGLVLASA
                     PVAAARSRVGHPLAAGRAPVLRRGSARRAGLLEPHLRRLVEDARTFLGPSPEHPWYAGA
                     VLLAGRGGTVALHEAIGHAVRYSAYDETTGTGVELPAGEQVPATPETVYDLASVSKLFT
                     AILAVRQMERGALELEGTVASYLPEFGAAGKDGITVLHLLTHTSGLAAWLPLYAEPTRE
                     DRLRRLWREEPLDPPGTVYRYSDLNLITLQLVLERVTGKGLDTLLREDVTGPLGMRWTR
                     YNPPASWRPRIAATEDARRPWSGLDRGMVHGEVHDENAYAFGGVAGHAGVFSCAWDLAV
                     LCRALLNGGAYGDARVLRPESVDLLFRDFNTAFPGDEHGLGFELYQHWFMGAMATPRTA
                     GHTGFTGTCLVLDPTTDTFLVLLGNSVHPVRTWRSGSAPRVAAADHLARAVPVRPAEGR
                     EAWFSGMASGASAVLTLPEVALGDGAEEGADGAGARLRFSVWWDTERTFDVLRLEASGD
                     GGGTWEPVPFTTSRPGQAPVERPEGALHGFSGRVWHRALADLGAWRGRAVRLRWRYTTD
                     ARYVGRGAYVDGVRIEDGGRTVFDGSRRGDAGRVTADGWSLSAD"
     gene            complement(13908..14207)
                     /locus_tag="BMY40_RS13970"
                     /old_locus_tag="SAMN05216481_10627"
     CDS             complement(13908..14207)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526393.1"
                     /locus_tag="BMY40_RS13970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10627"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_093659284.1"
                     /transl_table=11
                     /translation="MTTPLTLTDQRRPDGTPVLVAEGEIDMSNVGEFRASVDRAAAGGD
                     GRLVVDLTAVDYLDSAGLAALFAHADRLELIAPPLLDPVLTVSGLADLATVRIA"
     gene            complement(14204..18292)
                     /locus_tag="BMY40_RS13975"
                     /old_locus_tag="SAMN05216481_10628"
     CDS             complement(14204..18292)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139777.1"
                     /locus_tag="BMY40_RS13975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10628"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_245770095.1"
                     /transl_table=11
                     /translation="MAGRMRAFDWAGTPMGDPAGWPASLRTACRICLTSRYPMFLWWGD
                     DLRLLYNDAYQHLLGNKHPALARPGRQVWGEIWDVIGPMLRSVTETGKATWSEDLLLKM
                     ERHGYLEETYWTYSYSPLHDEDGRVRGVFTACNETTERVVGERRLAVLQDLGAQAGTAR
                     SVGEACRLVARVLGRAQRDVPFAAVYLRRPGGEPVPAAVSPPGTAPGPPPGGRGGWPLE
                     RVLATGEPVVVEDVLRRFGRLPSGEWEKPPTQAVVLPLPGETGTGPIGAIVLAVSAGRV
                     LDDSYRTFLDLVARQTAALVNGAVAYEVQQRRAEELAELDRAKTAFFSNISHEFRTPLT
                     LIMGPLEELRGQLAGAGEQVREELEVIRRNGLRMGKLVNTLLDFSRIEAGRMQARFEPV
                     DLAAVTAELASVFRSAVERAGLAFEVDCPALPEPVHIDRDMWEKVVLNLLSNALKFTFD
                     GSIGVTLRAEDGQAVLRVSDTGIGVPPDELPRLFERFHRIENVRARSNEGSGIGLALVK
                     ELVGLHGGTITADSTEGGGTVLTVRLPFGSAHLPAGSVARGAEPFPVSDADPYLQEALR
                     WLPEERGEAGPEESAQPAAGRAESVPPVPGEARARVLVADDNADMREYLQRILAPGYRV
                     TTVADGREALEAVRADAPDMVVSDVMMPRMGGLELVEALRADSRTAGVPVLLLSARAGQ
                     EASIEGLEAGADDYLVKPFSAAELLARVRAAVKLSRLRNHHAQWRTALVDSLQEAFFVC
                     DEEGAVVEINSAFTDILGYGPEGLPYRPKHPWWPDEETDPEAHRAIEKAFAQIVGEEKG
                     SYITPVKHRDGHRLWVYASFNEVRDPDTGRRMVVGTFRDVTAERLTAQRETALAALSVR
                     LSEAGSVPEALRAALDELRGVWRAPRALAVTWDGPDRVPRLVAAVPGTAWGEPGDPARG
                     AVEALRGRNPLHPVATGGPAGVGITLEHPGGPLALWVEASQERPFISEDHTLLAVLGGY
                     LGQMLQRVHAFEQQRETALALQRAILGPDRLPQGFAVRYEPAARPLEVGGDWYDTVELP
                     DGRIGIVVGDCVGRGLEAATVMGQLRSACRALLLQFADPAQVLSALDRFAALIPGATCA
                     TVFCGVLDPVTGRLAYSSAGHPPGILTHPDGATELLDQGRSIPLAVQPGRPRPTGTRTM
                     PPASVLLLYTDGLIERRSRPLYAGIAAASAAARRGRAADLEELADAIRTGLEPAGGYDD
                     DMALLLYRHPAPLEVAFPADSAQLARVRSALRDWLGRLDAGPRLTQAVLVAAGEACANA
                     IEHGHRHNPGRTVCLRAAATADGLRLTVTDTGSWKPPQPEANAHRGRGLILIHALMDQV
                     DIVTDDAGTTVDMHVRITR"
     gene            18644..19000
                     /locus_tag="BMY40_RS28600"
                     /old_locus_tag="SAMN05216481_10629"
     CDS             18644..19000
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613182.1"
                     /locus_tag="BMY40_RS28600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10629"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_245770082.1"
                     /transl_table=11
                     /translation="MPDRDLTVTLRPHPAGPFLLEVSGELDHHTADRMREALNELPRDR
                     GTAVVIDLSGLVYCDSSGITVLITAYHLTQSLGGSLALAGLDDDIMRVFGIVGLDQIFA
                     FYDSVEEAVAALSG"
     gene            complement(<19260..20207)
                     /locus_tag="BMY40_RS13985"
                     /old_locus_tag="SAMN05216481_10630"
                     /pseudo=""
     CDS             complement(<19260..20207)
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262490.1"
                     /locus_tag="BMY40_RS13985"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216481_10630"
                     /product="serine/threonine-protein kinase"
                     /pseudo=""
                     /sec_met_domain="Pkinase (E-value: 5.1e-52, bitscore:
                     170.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRESTLIQGRYRLLGLVGRGGMGQVWRAHDESLDREVAVKCLKPP
                     GSRPGPQETVALRERFRREARLAASLQHRGVTVVHDFGEHDGVLYLVMELLDGHDLSRL
                     LELGGRRPLPVPDLFDIAEQMAAALAYTHDRGIVHRDLKPANVVRTADGTVKICDFGIA
                     RLDRGTGPAAGTAGGFPMGTPHYMSPEQITGAHLDHRSDLYSLGCVLYEIATGTPPFDL
                     EDTWGVLVGHRETAPRPPRELRPDLPGDLERIILDLLAKEPDGRPGDAAELGRRTAEAR
                     RAGSPDGRRTPLRQSPGSAERLPEWAYGVRTGARA"
     misc_feature    complement(20858..20867)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 gtcgtcggcc aggtcctcgg ggcgggggaa ggccagggcg gcgatggcca gatgggccag
       61 gccgtgcagg aatcggtcgg tggagtcgga ggtggcgcgg cgggcgtagt cgcccatgcg
      121 cacggcgaag acggagtcct cggcggcggt gacggccatt cccgcgcgcg gggagacctc
      181 cagcacgacc agcccgaggc cggtggcgac ggcgtcggcg agccgggcga atgcgggctc
      241 ctcccggtag cggcgcagca gctccgcgta ctcggcgtca cgggcgggca gcagcttggg
      301 ctggaggccg aaggagacca gccgggcggc gtcggcggcg tccggcgggg agagggggac
      361 cctgccggga gcggcgggaa cgccggaccg ttcgccgggc tccgctccgg gcccgccgtg
      421 tccgcccggc ccctcctgct cgtcgtggac gccgtaaccg gggtacgggc cgtactcgtt
      481 caagatgcca cctccgtgcg gtccgccgcc atgcccgcgg cgtccagcag ggccgtcccc
      541 accacgaggt cggcgccgcc gaactccggg tcgtccagtt ccgtgccgtc gtccacggcg
      601 aacagcaggc gccgttcgcc ctgccggtag gcggtgccga ccggcgggct ggcggcgtgc
      661 accgccagca gggccaccag gtagggcagc tccgggtcgc ggcggcgggc ctcggccagc
      721 aggcccgaca gccggcgcgg ggcgtcggcg ggcagctcca gcagctcccg ggcggcctcc
      781 atctgctcct cgctgaaccg gctgtcgtcg ggggtggcga ccagatccgg ctcgggcatc
      841 tcggcgccca ggtgctcgcg gggcgcgggc ggggtgagca gcatctcggt caggtccccc
      901 agccgtacgg ccgccggggt gcgcagcccg gtgccgcggg cgaagaaggc gtcggtgacc
      961 ttggtggccc gctccaccgg cagcggcagc acgggggcga gcagctgccc gtacaggtcg
     1021 aggccggcgc cggcggcggg cggggcgaac gcctgccggt cctgctcggc gcggaagagc
     1081 ggtccggcct ccagcagccg ggactggagc tgggtgtggc gccggatgca gtccttgacg
     1141 atgtcgacca gttcggcggc gcgcagcttg tggccggggt tcttgtcggc gggggcctcg
     1201 tcccgcgccc tgcggatgtt ggtgaggatc gcgttctcgt ggcggtagcg gtcggcgacg
     1261 tggtcgagcg cctcggcgat catgtcgggg acggcgttga gccagtcgac cgcgcggacg
     1321 ttgcgccggg tggcctccag ggtgcggcgc agcgtctcgg cgtactgcac ggtgcggtag
     1381 cgggcctgct cggcggcgag ctgggcgtcg gccaggcggc cccggctgac cagcacctcc
     1441 agcttgacct cggcggcgat ctgcgcgctg gtgacatcgg tgtcgagggc gccgaccagg
     1501 acgttgaccg cctcgtcggt ggtgcgcagg tacacccctc cgcccggccc cggcacctcc
     1561 tcgatcagct tgaagtcgta gtcgcgccgc acgtactcgc cgtcggggcc gaaggtgccg
     1621 tagacggcgc ggaacccccg gtcgacgctg ccgacgttga tcaggttctc caggacccag
     1681 cgggcgaccc gctcgtgctc ggcggcgggc cgccgcggcg cctgggccgc gacccgcggc
     1741 agcagccggg ccactatctc ctcgtggtcg gcgccggtgt cgaagtccat gtgcagggtg
     1801 accaggtcga tggcggccag cgccacctcc gccatcgagt acgtgccgta ctccccggcc
     1861 aggttggcct tgcgcgcgtc caggtcgtgc aggggcgcgg tgcaggccag cgcccgcaga
     1921 cgccgggcca ggccctcgtc ggcggccggg cccggtgcgg gccgcgcggc gccgggggat
     1981 gaggcggata ctgctgtggt cacacggcac agattaggcg ctggcactga cagagatcga
     2041 aacggcggga acgcgcccgg cggcgcgggt ccccggggcc ggtccggtac gctccgggcc
     2101 ggccccgggg gcccgcgccg gccgggtcag cgggccgccg cgccgccgga gccgagccgg
     2161 ccgcgcaccg cgctctgcac gccctcctcc tcggcgggat cggcggccag ccgccgcagc
     2221 cgctcgacga cccgggtgtc gccggtcgcg gcgtggcggg cggcgatctc gcgggtggac
     2281 tcctcgcagt cccacaggca ctcgatggcg aagcccgccg cgaaggcggg gtcggtggcg
     2341 gccagggcgc gggcggcccg gccgcgcagc tgggaggagg cggtctcgcg gtagacgtgc
     2401 cgcaggaggg gggcggcgcg gtgcacggcc agccggccgg cgccgtcgac cagcggccac
     2461 agggcgtcgg agtcgggccc ctcggcgcgc acggtgcggc gcagcgcggc cagcaccagg
     2521 ggggcgtccc gttccgcgcc gtggcaggcc agcagcgtgg cggccgccgt gcccaggggg
     2581 tcctcgcgcc gcgcccagcg gcgggcgcgt tcgagcgcgg cggtgccgcg cgtccgggag
     2641 agggcgtcca gcgcggcccg ggcgacggtg ccggagggac cgcccgcgag gcccgcgggg
     2701 tcggcggccg ggtcccccgc ggcggcctcg atcaggtcca gtgcggccgg gtcgccccgc
     2761 tcggcgaggt ggcgcagggc gacggcgcgc gcgatgtcgg ggccggagcg ggcggcgtcg
     2821 agcagttcgg ggcggtcgtc gggcccggcg acggcggtca ggcagcgggc cgccgcggcc
     2881 tcgcggtgcc gcgggtcggg gcccggagcc gccatgggca ccgcggaccc cgccgacgcg
     2941 gaggcgagcg gtccgtcggc ggcggggtgg gcggtggaga ggagtggatc gccttcctgg
     3001 gcccagtcga gcaccgcgcg cacgctccag ccggggcgcg gcccggccgg cctcatctgg
     3061 cgctgccagc ggccgaagga gccctgctca cgggcgcgtc cgaggcgttc gccctgctcg
     3121 gggcgggccg ggtcctcggc ccacagccgc cagggcctgg gctcgaaggc gtcgcggacg
     3181 gccgccgcca gctcggcgtc gccctcgggg gtgcgcggga agcgcgccag gacggcgggg
     3241 cccagcgggc gcagtccggc gtcgtcgtcg cggacggcca gttcgtccag ggcccagcgc
     3301 cagttggcgc cgcgcgaggc gtagcggcgc agcagcagca gtgcgccgcg gtcgccgtag
     3361 gaggccaggt gcccgaggac ggagagggcc agtccggtgc gctcctcacc gccgtcggtg
     3421 aggtcgtcgg ggccgaacag gtgctcctcg atgtcgtcga gcccggcgtc cagctccacg
     3481 tggagccgtg cgtagtacag ggagcggtgc tcgagccgcc agtcgcgccg ggggtcacag
     3541 cgcaggcagt ggctcagcgc ggcgagcgct tcggcacgcg gggccgccag agcgtgcagc
     3601 gtgccgtcgc cgcggcccct ctggaggagg ccgagcagcg taccgctggg cgctatgtcg
     3661 gaatcgacgg aatcggcgaa cataaggtca gcatccggtg cggggtgagg gactggcaac
     3721 gggatttccg ctctccgggg ttccggccgg tcaccgcggg ttcgtccccc gttcgtcccg
     3781 ggtcctccca cgggttcccg gcaccgtgcg gaaagcggtc actccggccg ccgaaggata
     3841 ccgggaccag ggcgccgcgc cgagtccgcg cgcacgggcg gtgcggagac ggcggccccg
     3901 ggcgtccgcg gccgcaggac ggccgggtgc cccggggccc gccgccgcta caccgccgcc
     3961 ccgcccccgg cccgccgggg cgcgggcacc gcggctgtcg caccggagaa gccgggggcc
     4021 gcggggaggg cgagcgcgat ctcctcgcgc aggtcctcga ccttggggta cccggcgtac
     4081 cgtccggtga gccggtacat ctcccgcagc cggtcccagg tgcggtggga ggaggtgttg
     4141 ccgatggtga ccagggccag ccgcgcgtag cggtccgcct gctccgggtc gtcggcgatg
     4201 aagcaggcgg aggcgagtga gatgtagtcg aggatcttcg acctctcgcg gcccttctcc
     4261 cgcagccgca gcgcctcctt ggcgtgcttc tcggccgtcc tcgccgccga ggggtcgtgc
     4321 tcggccaggg tgcggtacgc cagcgcctgc atcccgtgca ggtcggcctc gtcgaacagc
     4381 tgcatccagc tcggcggcgg tacgtccccc cggtcggaga cgaacaggtc ctcggcccgg
     4441 ccgagggtgc gccgcatcgc ctggccgcgc cccatggagg cgtgggccca cgcctcgatg
     4501 gtgtggagca tcgcgcgggt gcgcggcagg gtctcctcgc cgcagccggc cttggccagc
     4561 ttcatcaggt ccagggcctc gtcgggtctg cccaggtgca ccatctggcg cgcggcccgg
     4621 gagacggcct ccccggcgcg aggccggtcg ccgccctcgc gggccgcgtg cgcggcgatg
     4681 acgaagtact tctgcgcggt gggctccagg ccgacgtcgt gggacatcca gccggcgagg
     4741 accgccaggt tggccgccac cccccacagc cgccgctgga tgtgcggcgg gtggcggtag
     4801 gcgagcatgc cgcccacctc gttgagctgg cccaccaccg ccttgcgctg gagaccgccg
     4861 ccgcgggccg cgtcccaggc gcggaagacc tccacggagt gttccaggga ctcgacctcc
     4921 tccacgccga cgggtgcggc ctcgtagcgg tcggaggagg cgggggcggc gagggcggag
     4981 ccgcccggcc ggggggcgcc cgccggagcc ggatcggtcc ggagccagtc gtacagggcg
     5041 ctgctgagcg ccggtcctgc ggtgagcgcg gcgcccgcgc ccaccaagcc gcgtcggttg
     5101 agcatgaggt ccattcccgt gaattcggtg aggaccgcgg cggtctgttc gggggcccac
     5161 ggcagtccgt ggacggactg ccgtctccct gtctgtccag accggctgaa cccgaggtcc
     5221 tcgatggtca cgacacggcc gagtcgctcg gtgaacaggg tcgccagcac cttcggcacc
     5281 gggtcgcgcg gggtctcccc catgtcgatc cagcgcctca cccgggaggt gtcggtcgcc
     5341 agctgcgggt ggcccatggc cgccgcctgc cggttcacgc gccgggcgag ttcgcccttg
     5401 gaccagccgg tgaggccgaa aaggtccgcg aggcgggtgt tgggtccctt ggtcacgtcg
     5461 tagcccccag gttctcggct gtgtcgacag tagccctcgc gggccgcccc cgaaggggcg
     5521 cgcgggtatt cgccagggtt cgccagggtc cgccagatgg tgtgccaccc gtgcccgggt
     5581 gtgctgtagg aacgcgccac cccgtccggt cgccggcttc cgcattcccc agggtgcggc
     5641 acgccccggc cggccgggtg gcgcggcaat ccgtcggcgc acgaagggat ccggctcgtc
     5701 catgaatcca acaccgtctc ccgtgccggc cccggtccgg ccgcgtccgc gaccgcagta
     5761 cggcaccgtc ctccccgagc cggtgcgcac accgcccgcg gtcgccggcc tgccccggcc
     5821 gcgccgggcg cccggcgcgg gggtcctgcc ggccgccggg aggccggagc cgtccggccc
     5881 gcgggacggg cggctgcgca ccgccatcgc ctcggtgcac cgggtctgcc cggagttcca
     5941 gccggtgcag gtgctgcgcc ggggcgggcg ctcggtgctg ctggcgggca ccgtcggccg
     6001 cggcggcgcg gtcgccaagt gcctgctgga ccactcgccc gcgcgggtcg agcggttccg
     6061 gcacgagata gcggtctacc gcgccttcgt gcgccagcgg ccgccggtgc gggtgccccg
     6121 gctcatcgcc gccgaccccg acggctgcgt actggtcgcc gagcgggctc cgggccgccc
     6181 gatggcactc cagcggcatc cgctggaact cccgtcgcct gccgacctgc gcgcggtgct
     6241 gggcgcggtg tgccgggtga acgcctggca gccgcccgca ggcctcttcg gggctccggt
     6301 cgactacggt gtgcggatcg cccgctacca cgggctggga ctgctgacgg atcgtgacct
     6361 gggcgatctg cggaagctgc tccacggcct ggcacgcggc ggcggccgcg cgcagttctg
     6421 ccacggcgac gccctgccgg tgaacgtgct gctctccccg gccggtccgg tgctgctgga
     6481 ctgggagcac gcgggctggt acctgccggg ctacgacctg gccaccctgt ggtcggtgtt
     6541 gggcgacagc ccgatggccc gccgccgcat cagccggctc gcccaggccg ggggccgcga
     6601 cgcgcgggac gccttcctgg tgaatctgat gctcgtcctc acccgggagg tccgtgcctg
     6661 cgagacggcc gtgcagcgcg ccatgcggga cccggggccg gccccgggca gcgaccggac
     6721 cggcctgctg agcaccggcg aggagcagcg gctgctgctg cgccgtctgc acgacgactg
     6781 cgcgatggtc cggcgcgcgg tgcgggcggc ggtgggcaca cgctgacggc cagcccctgc
     6841 ggcgccccgt cgccgggccg ctcccggccc ggcgacgggg cgccgcaggg tgctgcgggg
     6901 cgccgcgggg cgtcaccggg ctggacctgt gacgccgcgc aggtccgggc ccattccggg
     6961 gtgaagactc ccccggatgg cctctgacgt gcgagaaccc ttcagctacg ggttctcgca
     7021 cgatcgttga cggatcgccg gccggccgat acccctgtgg gcagtcccgt gccgtgccgc
     7081 gccgcgccac cgcggcgtac ccctcaggag gccgtcttgc caggagccgt tccagtccgc
     7141 ccgtcagctt ccccgcccgg ttccgcccgc cggcggctgc gggcgctcac cgcggcctcg
     7201 gtggccgccc tgctgctgcc cctcctccct gccaccgccg acgccggcgg gcgggagccg
     7261 gattcgctgc aggaggcgtt cgcccgcgcc gccgaccggt accaggtgcc cgagagcgtg
     7321 ctgctggggg tgtcgtacct gcagtcccgc tgggacggcc accgcggcgc gcccagcgtc
     7381 tcgggcggct acgggcccat gcacctgacc gacgcgcgca ccgccctggc cgaggacccc
     7441 caccacagcc acggcaccga ggacgcgcgc ggcgacaccg cccgcgccgt cagacaggtg
     7501 cacgacgcgg tgcccgatcc cgccgcgctg cccgcccggc tgcgcaccct ggagcgggcg
     7561 gccgagctga ccgggctgga cgaggaggag ctgcggcggg acccggccgc caacgtcgcc
     7621 ggcggcgcgg cactgctggc cgccgcccag aaggagctgg gcctgccgct cagcgacgac
     7681 cccgcccagt ggtacggggc cgtggcgcgc tacccgggct ccggggacgc gcgggcggcc
     7741 ggggtcttcg ccgacgaggt cttcgacgtg ctccgcgagg gcgagcggcg caccaccgac
     7801 tccggccagc gcgtggtgct ggagggcgcc ccggacctgg ccccggacac cgcgcagctg
     7861 gacggcccgg acctgcgtcc ggcgtcctcc gggagcgacg ggccggtgga gtgcccgagg
     7921 tccgtctcgt gcgagtggct cccggcaccg tacgaggagt acaccaatcc cgacggatcg
     7981 ccgaactacg gcaaccacga caaggcggac cggcccgcgt cgcagaagat cgactacatc
     8041 gtggtgcacg acaccgaggc gacctgggac accaccctgc ggctggtgcg gaacccgaag
     8101 tacgtctcct ggcactactc cctgcgcgcc tccgacggcc acatcgccca gcacgtcccc
     8161 accagggacg tgggctggca cgcgggcaac tggtacgtca acgccaagtc gatcgggctg
     8221 gagcacgagg gcttcctgac cgcacccgac gcctggtaca ccgaggcgat gtaccgcacc
     8281 tcggcgcggc tggtgcggta cctggcccac aggcacggca tcccgctgga ccggcagcac
     8341 atcatcgggc acgacaacgt gccgggcgtg acgtccgcca acatccccgg gatgcacacc
     8401 gatccggggc cgtactggga ctggcagcac tacttcacgc tgctgggcgc gcccttccac
     8461 cccacggccg cgccggactc ggagctggtg accatccggc ccgactacga ggagcacagg
     8521 ccggtctaca cccggtgcga cggctccggg cagccctgtc cgccgcacgg ttcgggcgcg
     8581 gtgcgactgc acaccgggcc gagcgccgac gccccgctgg tgaaggacgc cgggctgcgg
     8641 ccgggcggcg gcgactccac caccggcgtc aacgacaccg gcgcccgcgc ctcgaccggc
     8701 cagcggtacg cggtggccga gcgccggggc gagtggacgg cgatctggta cctcgggcag
     8761 aaggcgtggt tccacaaccc cgccgacgcc ccgaccgcgg tgggctcccg gggcctggtc
     8821 gtcaccccga gggagggcgt ggagtcggtg cccgtctacg gccgcgccta cccggaggcg
     8881 tccgcctacc ccgaggggat cccggcccag gcgatctcgc cgctgccgta caaggtggag
     8941 gcgggccagg cgtacgcgct ggggctgcgg acgaagggcg agtactacta cgccaagacc
     9001 ttcgaccccg ccggccacgt ggtggtccgc ggcgaggagg agtactacca gatccagctc
     9061 gggcaccggg tggccttcgt caaggccgcc gacgtcacgg tgcggcccgc ccggcggtga
     9121 ggtgacgggc ggtcgcacgg tgtggggagg ggcgccgcga agcgcccctc cccactgtgt
     9181 ccctcatgtc ctcggctgtc cgcgcccgcc gctgcgtcag cgctggaaca gctccgcggg
     9241 cagcggcttc agcagctggt agaggtcctc ggtgatcggc cggtcccagc tggcgatggt
     9301 gaccagcacg ccgtcgctgc ggtcgaactg gacgcaggag atccgggtct ccgagcacag
     9361 gatccgccgc acgatcagga ggttgtcgtc cagcatcacc gggctctcct ccgttccggt
     9421 gacggtgacc tcctcgtcgt tctccagtgc cgccagcagc tgcgcgacct cgaaggggat
     9481 ctgtccctcg gccgtctcgc gggccgggga gccctccggc aggttcccga tgaccatggc
     9541 cggtccgcgc ccgccgaaca ggtcgtagcg caggaagacg ccctggcagc ttccgtccgg
     9601 cgcgggcagc agcccggcgc cgaggttgcc cggccagtcc cccgggtcca tggccagcac
     9661 gtcgaagtcg ggtccggcgg gtgtggcggc actgcggcgg cggagaaagg acatgcggcc
     9721 atggtacggg cccggtaccg ccgcggggct ccggcccgcg gccctcccgc ggcgggcggc
     9781 ggagggcgta cacgggtgtg aaccgggtgc ggtgctcccg cccgttcccg gtggagcgcc
     9841 gtttcgggca gcgccgcttc cgcgcactcc gcgtacaagg cggagcacgg agcgtccccg
     9901 gcactcttga ccggcaactg cctttggcca agggtggttc ggcgtatgcg cccgtcatcc
     9961 tcaccgccgc gctcaccgcc cgccaggagg cgtcatgtcc atgactgaag tcggtgccgt
    10021 cggggacacc gccggacggg agggcctgct gcggcggacg gcccgcctgg agataccctt
    10081 ccgcagcgcc gtcggccccg gtgtcgggaa ggccaggctc cacaccctcc ggtggctgcg
    10141 ggacttcggg ctgctcaccg gggaggccgc gttcgaggag tacgacgccc tgcggctgga
    10201 gcgggcgatg gcccgcttct atccacgggc cgcggaagag gacctgatgc tggccaccga
    10261 cgtcaacggc tggttcttcg tcttcgacga ccagttcgac ggccccctgg ggcggcggcc
    10321 gcgggacgtc acccgcctcg tggaccgcct ggtccgcgtc atggacgggc gggagccgcc
    10381 ggccggcgcc cccgcgggcc cgctggtcga gagcttccgc gatctgtggc accgcatcaa
    10441 cgagggaatg ccgccggtgt ggcgggaacg cttccgccgg cactggcacg gctatctgct
    10501 ggcccaccgc cgggaggcgc tcaaccgctc cggggaccgg ctgcccacgg tggaggagtt
    10561 cctggcggcc cggcggcaca ccatcggcat acagccctgc ctggacctgg ccgagcgctt
    10621 cggccgctac accctgccgt ccgcgctgca cggcggtcac ccgctgaagg agatgcggcg
    10681 gatcaccgac gaggtggcga tcttcgtcaa cgacatcgtc tcgctggaca aggagctggc
    10741 cgtcggcgac gtcaacaaca ccgtcgtcct cctgcggcac ggcaccggcc gcccgctccc
    10801 ggactgcgta cgggagatcc gcgccgccgc caacggacgg gtcgcccgct tccgggagct
    10861 cgccgcgggc ctgcccgccc tgctgggggc cgcgggcgtg cccggggagg cgcgggcgca
    10921 cgtggaggac tacgtcgacg gcatgcgcaa cgtgatgcgg ggcaacctcg actggtccct
    10981 ggagagccgg cgctacgacg acgccggggt ggccgccgtc agcggcgggc gcctgcgccc
    11041 gtgggccggc ctgccggacg aggcagtgcc ggaacgcgga gtcggggccg cgggtccggt
    11101 gcggccgtga ggcgggagac ggacggcggg acgacggtga acctctggcg cgcgggcctg
    11161 acccgcgtcc ccgaacaggt gtgggagcac cgggagtcgc gtgtgctgat cctcgcggac
    11221 aacgcgctca cctccctccc gccgcggatc ggccggatgc ggcgcctgcg caccctcgac
    11281 ctcggccaca acgcgctcac ctccctcccc gaggagatcg gggagctgac ggacctggac
    11341 ggctgcctct acctccacga caaccggctc accgcgctgc cgcgctcgct ggggcggctg
    11401 cgctcgctga cgtatctgaa cgtcggcgac aacccgctgg gcacgctgcc cgaggaggtc
    11461 ggcgacatgg cggggctggt ggaactgcgc gcccagcggt gcgggctgcg ggagctgccc
    11521 gcctcactcg ggcggctcac cgcactgcgg gaactctggc tgcgcggcaa cgccctggcc
    11581 tcgctgcccg ccgccgtacg cgggctgcgg gagctgcggg agctggaact gcgcgagaac
    11641 gccctggcac aggtgcccga ggcgctgcgc ggcctgccgc ggctgcgccg cctggatctg
    11701 cgggccaacc ggctgcgcac ggtgccggac tggctggagc gggagctgcc cgcgctggag
    11761 aagctggacc tgcgctggaa cgaggcggcg gtcgagccga agctgctgga ggcgctggag
    11821 cggcgcggct gcgtggtgct ccggtaggca cgagacccgc acggagcgct cgtccgccgt
    11881 gccgcggggg ttgactaatg gcacgctcgg gaagaaggtt tcagcgtttt cccggtccgt
    11941 tgaaagatac tttccccagg gggcacggta tgacaggttc ggcacgggat cgcgcaccgg
    12001 gccgggcgcc cgcatccggc cctgccgcga gcgagggcat cggccggcgg cagctcggcc
    12061 tccgggccct cgcgctcggc ggcggtctgg tcctggcctc ggcgcccgtc gcggcggccc
    12121 gctcccgggt cgggcacccc ctggccgccg gccgcgcgcc cgtcctgcgc cgcggctccg
    12181 cacggcgcgc cgggctgctg gagccgcatc tgcggcggct ggtggaggac gcgcggacct
    12241 tcctcggccc ctcccccgag cacccctggt acgcgggcgc ggtcctgctg gccgggcgcg
    12301 gcggcaccgt cgccctccac gaggccatcg gccacgcggt gcgctactcg gcctacgacg
    12361 agaccaccgg caccggcgtc gaactccccg ccggcgaaca ggtccccgcc accccggaga
    12421 ccgtctacga cctcgcctcc gtctccaagc tgttcaccgc gatcctggcc gtgcggcaga
    12481 tggagcgcgg cgccctggaa ctggagggca cggtcgcctc ctacctgccg gagttcggcg
    12541 cggcgggcaa ggacgggatc accgtgctgc acctgctcac ccacacctcc gggctggccg
    12601 cctggctccc gctgtacgcc gagcccaccc gggaggaccg gctgcggcgg ctgtggcgcg
    12661 aggagcccct ggacccgccg ggcacggtct accgctactc cgacctgaac ctgatcaccc
    12721 tccagctcgt gctggagcgg gtcaccggca aggggctgga cacgctgctg cgcgaggacg
    12781 tcaccggacc gctgggcatg cggtggaccc gctacaaccc gcccgcctcc tggagaccgc
    12841 gcatcgccgc caccgaggac gcccgccgcc cctggtcggg tctggaccgg ggcatggtgc
    12901 acggcgaggt gcacgacgag aacgcgtacg ccttcggcgg cgtggccggc cacgccgggg
    12961 tcttctcctg cgcctgggac ctggccgtgc tgtgccgcgc cctgctgaac ggcggcgcgt
    13021 acggcgacgc ccgcgtcctg cggccggagt cggtggacct gctcttccgc gacttcaaca
    13081 ccgccttccc cggcgacgag cacggtctgg ggttcgagct gtaccagcac tggttcatgg
    13141 gggccatggc gaccccccgc acggccgggc acaccggctt caccggcacc tgcctggtgc
    13201 tggacccgac caccgacacc ttcctggtgc tgctgggcaa ctccgtgcac ccggtgcgca
    13261 cctggcgctc cggcagcgca ccgcgcgtgg ccgccgccga ccacctggcc cgggccgtgc
    13321 cggtacgccc ggccgagggg cgcgaggcct ggttctcggg gatggcgagc ggcgcctcgg
    13381 ccgtgctcac cctgcccgag gtggcgctcg gcgacggtgc ggaggagggc gcggacggcg
    13441 cgggcgcccg gctgcgcttc tccgtgtggt gggacaccga gcgcaccttc gacgtcctgc
    13501 gcctggaggc gtccggcgac ggcggcggca cgtgggagcc ggtgccgttc accacctccc
    13561 gccccggcca ggccccggtg gagcgcccgg agggggcgct gcacggcttc tccggacggg
    13621 tctggcaccg ggctctggcg gacctgggcg cctggcgcgg ccgggcggtg cggctgcgct
    13681 ggcggtacac caccgacgcc cgctacgtgg ggcgcggcgc gtacgtcgac ggagtccgga
    13741 tcgaggacgg cgggcgcacg gtgttcgacg gctcgcggcg cggggacgcc gggcgcgtga
    13801 cggccgacgg ctggtcgctc tcggccgact gacgcccggt caccgccgga gcccgccgga
    13861 cggtccgtcg gcccgtccgc ccggcggccc ggcggcccgg cggcccgtca ggcgatgcgc
    13921 acggtggcca ggtcggcgag tcccgagacg gtgaggaccg ggtccagcag cggcggggcg
    13981 atcagttcca gacggtcggc gtgggcgaac agtgccgcca gcccggcgct gtccaggtag
    14041 tccacggcgg tgaggtccac aaccagccgt ccgtcgccgc cggcggcggc ccggtccacc
    14101 gaggcccgga actcgccgac gttgctcatg tcgatctcgc cctcggccac gaggaccggg
    14161 gtgccgtcgg gacgccgctg gtcggtgagc gtcagtgggg tggtcaacgt gtgatcctca
    14221 catgcatgtc tacggtggtt ccggcgtcgt cggtgacgat gtcgacctgg tccatgagcg
    14281 cgtggatcag gatcaggccg cggccgcggt gggcgttggc ctcgggctgc ggtggcttcc
    14341 agctcccggt gtcggtgacg gtcaggcgga ggccgtccgc ggtggccgcg gccctcaggc
    14401 acacggtacg gccgggattg tggcggtggc cgtgctcgat ggcgttggcg caggcctccc
    14461 ccgccgcgac caggaccgcc tgcgtcaggc gcgggcccgc gtccaggcgc cccagccagt
    14521 cgcgcagggc gctgcggaca cgggcgagct gggcggagtc ggcggggaag gccacctcca
    14581 ggggcgcggg atggcggtag aggagcagcg ccatgtcgtc gtcgtagccg ccggccggtt
    14641 ccagaccggt ccggatggcg tcggccagct cctccaggtc cgcggcgcgc ccccgccggg
    14701 cggcggccga ggccgcggcg atgcccgcgt acagcgggcg gctgcgtcgc tcgatcagac
    14761 cgtcggtgta cagcagcagg acggaggccg gcggcatggt gcgcgttccc gtgggccggg
    14821 ggcggcccgg ctgcaccgcc agggggatgg agcggccctg gtcgagcagt tcggtggcgc
    14881 cgtccgggtg ggtcaggatg cccggaggat ggccggcgct gctgtaggcc agccggccgg
    14941 tcacggggtc gagcacaccg cagaagacgg tggcgcacgt cgcgccgggg atcagggccg
    15001 cgaaccggtc gagcgcgctc agcacctggg ccgggtcggc gaactgcagc agcagggccc
    15061 ggcaggcgct gcgcagctgg cccatgacgg tggcggcctc caggccgcgg ccgacgcagt
    15121 cgccgacgac gatgccgata cggccgtcgg gcagctcgac ggtgtcgtac cagtccccgc
    15181 cgacctccag gggccgggcc gcgggttcgt agcggacggc gaacccctgt ggcaggcggt
    15241 cggggcccag gatggcccgc tgaagggcca gggcggtctc gcgctgctgc tcgaaggcgt
    15301 ggacgcgttg cagcatctgc ccgaggtaac cgcccagcac ggccagcagg gtgtggtcct
    15361 cggagatgaa gggccgctcc tggctggcct cgacccacag cgccagcggc ccgccggggt
    15421 gttccagggt gatgccgacc ccggccggcc cgccggtggc caccgggtgc agggggttgc
    15481 ggccgcgcag ggcctcgacg gccccgcggg ccgggtcgcc cggctccccc cacgcggtgc
    15541 cgggcaccgc ggcgaccagc cggggcaccc ggtccgggcc gtcccaggtg acggccagag
    15601 cgcggggggc ccgccacacc ccgcgcagtt cgtccagcgc ggcccgcagg gcctcgggga
    15661 cgctcccggc ctcggacagc cgtacgctca gcgccgccag ggcggtctcg cgctgggcgg
    15721 tgaggcgttc ggcggtgacg tcccggaagg tgccgaccac catgcgcctg ccggtgtcgg
    15781 ggtcgcggac ctcgttgaag gaggcgtaca cccacagccg gtgcccgtcg cggtgtttga
    15841 cgggggtgat gtagctgccc ttctcctcgc cgacgatctg ggcgaaggcc ttctcgatgg
    15901 cccggtgggc ctcggggtcg gtctcctcgt ccggccacca ggggtgcttg ggccggtagg
    15961 gcaggccctc cgggccgtag ccgaggatgt cggtgaaggc ggagttgatc tcgacgacgg
    16021 cgccctcctc gtcgcagacg aagaacgcct cctggagcga gtcgaccagc gcggtgcgcc
    16081 actgcgcgtg gtggttgcgc agtcttgaca gcttcaccgc ggcccgtacc cgtgccagca
    16141 gctccgcggc ggagaacggc ttgaccaggt agtcgtcggc gcccgcctcc agcccctcga
    16201 tggacgcctc ctgcccggcc cgggccgaca gcagcagcac cggcaccccg gcggtgcggg
    16261 agtcggcgcg cagtgcctcc accagctcca ggccgcccat ccggggcatc atcacatcgc
    16321 tgacgaccat gtcgggggcg tcggcgcgga ccgcctccag ggcctcccgg ccgtcggcga
    16381 ccgtcgtcac ccggtagccg ggggccagga tccgctggag gtactcgcgc atgtcggcgt
    16441 tgtcgtcggc gaccagcacc cgggcccgcg cctccccggg gaccggtggc acggactccg
    16501 cccgcccggc ggccggctgt gcggattcct ccggtccggc ctccccgcgc tcctccggca
    16561 gccaccgcag cgcctcctgg aggtaggggt cggcgtcgga gaccgggaac ggttcggcgc
    16621 cccgtgccac cgaaccggcc ggcagatggg ccgacccgaa gggcaggcgg acggtgagta
    16681 cggtgccacc gccctcggtg ctgtcggcgg tgatcgtgcc gccgtgcagg ccgaccagct
    16741 ccttcaccag cgccagtccg atgccgctgc cctcgttcga gcgcgcgcgg acgttctcga
    16801 tgcggtggaa acgctcgaac agccgcggca gctcgtccgg gggcaccccg atgccggtgt
    16861 cggacacgcg cagcaccgcc tgcccgtcct cggcgcgcag cgtcacgccg atggagccgt
    16921 cgaaggtgaa cttcagcgcg ttgctcagca ggttgaggac caccttctcc cacatgtcgc
    16981 ggtcgatgtg gaccggttcg ggcagcgcgg ggcagtccac ctcgaaggcc aggccggccc
    17041 gctccaccgc cgagcggaag acgctggcga gttccgcggt gacggccgcc aggtccaccg
    17101 gctcgaagcg ggcctgcatc cgcccggcct cgatgcggga gaagtccagc agggtgttga
    17161 cgagcttgcc catgcgcagc ccgttgcggc ggatgacctc cagctcctcg cggacctgct
    17221 caccggctcc ggccagctgc ccgcgcagct cctccagcgg gcccatgatc agggtgagcg
    17281 gggtgcggaa ctcatggctg atgttggaga agaacgcggt cttggcgcgg tccagctcgg
    17341 cgagctcctc ggccctgcgc tgctggacct cgtacgccac cgccccgttg accagcgcgg
    17401 cggtctgccg ggccaccagg tccaggaagg tccggtagct gtcgtccagc acgcgcccgg
    17461 cgctgacggc caggacgatc gccccgatcg gtcccgttcc ggtctcgccc ggcagcggca
    17521 ggaccaccgc ctgtgtgggc ggcttctccc actctccgga cggcagccgc ccgaaccgcc
    17581 gcaggacgtc ctcgacgacc accggctcgc cggtggccag cacccgctcc agcggccagc
    17641 cgccgcggcc gcccggcggg ggcccggggg cggtgccggg cgggctgacg gcggccggga
    17701 ccggctcgcc gccggggcgg cgcaggtaga ccgcggcgaa cggcacgtcc cgctgcgcgc
    17761 ggcccagcac ccgggcgacc agccggcacg cctcccccac gctgcgggcg gtgcccgcct
    17821 gggcgcccag gtcctgcagc acggcgagcc gccgctcgcc cacgacacgc tcggtggtct
    17881 cgttgcacgc ggtgaacacc ccgcgcaccc ggccgtcctc gtcgtgcagg gggctgtagg
    17941 agtacgtcca gtacgtctcc tccaggtagc cgtgccgctc catcttcagc agcaggtcct
    18001 ccgaccaggt ggcctttccg gtctccgtca ccgaccgcag catcgggccg atgacgtccc
    18061 agatctcgcc ccacacctgc cggcccggcc gggccagcgc gggatgcttg ttgcccagca
    18121 ggtgctggta ggcgtcgttg tacagcaacc gcaggtcgtc gccccaccac aggaacatgg
    18181 ggtagcggga ggtcaggcag atgcggcagg ccgtgcgcag actcgccggc catccggccg
    18241 ggtcgcccat cggggtgccc gcccagtcga aggcgcgcat ccgcccggcc atctcgctgt
    18301 gcccggggaa gagcagctcc agcggcccgg ccccgtcagc gtcgcccatc gcctctgccc
    18361 tcctcgccca ccgcgcgtac cggtgtcccg cggtcccgcg tcacggatgc gcatatccac
    18421 tggtacggcg acgatgcgcc gcgaccggtc ccgtaggata aacgcggccg gccacggcct
    18481 gcggcgcggt cggcccgcgg ggttcactcg ccccgtaagc gggcagtcga tcagcgtccc
    18541 ggcggagccg ccccggagcg ttccgcctcc ggccccggag ccgtcccgcc tctccggccg
    18601 tgccggggaa cgaccggacc gaccagcgcg tacaggagaa cgggtgcccg accgagatct
    18661 gaccgtcacg ctgcgccccc accccgccgg cccctttctg ctggaggtgt ccggcgaact
    18721 ggaccaccac accgccgaca ggatgcgcga ggcgctgaac gagctgcccc gagaccgcgg
    18781 gaccgcggtc gtcatcgacc tgtccggcct ggtctactgc gactccagcg gcatcaccgt
    18841 cctgatcacg gcctaccacc tcacccagtc cctgggcggc agcctggcgc tggccggtct
    18901 ggacgacgac atcatgcgcg tcttcgggat cgtcggactg gatcagatct tcgccttcta
    18961 cgacagcgtc gaggaggccg tggcggccct ctccgggtga tcccgccggg tggaccgggg
    19021 ccgcgggccg aaagcgcgga ccgggccgcg gctccggcgg ccccgggtca gtccggcgcc
    19081 gcgccggccg gcgagcgggg ccggcgggcc gcggcggggt cctcgccgcc gggcgcgtcc
    19141 gggacgcccc gcccggcacc tgcgcctgca ccggagccgg tccacgggcc gctgagcacc
    19201 cccggatatc cggacccggg gaacaccgaa ggaccggaac gcggcggccg tccggcgacg
    19261 gccctggcac cggtgcgcac gccgtacgcc cactccggca gccgctcggc ggacccgggt
    19321 gactgccgga gcggggtccg ccgcccgtcc gggctccccg cgcggcgcgc ctcggcggtg
    19381 cggcggccga gctccgccgc gtccccgggc cgcccgtccg gctccttggc cagcaggtcg
    19441 aggatgatcc gctccaggtc cccgggcagg tcgggacgga gttcccgcgg cggccggggc
    19501 gcggtctcgc ggtgaccgac gaggacgccc caggtgtcct ccaggtcgaa gggcggggtg
    19561 ccggtggcta tctcgtacag cacgcagccg agcgagtaca ggtcgctgcg gtggtcgagg
    19621 tgggctccgg ttatctgctc gggcgacatg tagtgcgggg tgcccatggg gaagccgccg
    19681 gcggtcccgg cggccgggcc cgtgccgcgg tcgagccggg cgatgccgaa gtcgcagatc
    19741 ttcacggtgc cgtcggcggt gcgcaccacg ttggcgggtt tgaggtcgcg gtggacgatg
    19801 ccccggtcgt gggtgtaggc gagggcggcg gccatctgct cggcgatgtc gaagagatcg
    19861 ggcacgggca gcggccgccg cccgcccagc tccaggagcc ggctgaggtc gtgtccgtcc
    19921 agcagctcca tcaccaggta gagcaccccg tcgtgctccc cgaagtcgtg gacgacggtc
    19981 acgccgcggt gctggagcga ggccgcgagg cgcgcctcgc ggcggaagcg ctcgcgcagc
    20041 gccacggtct cctgggggcc gggccggctc cccggcggct tgaggcactt gacggcgacc
    20101 tcccggtcca gcgactcgtc gtgcgcccgc cacacctggc ccatgccacc gcgtccgacg
    20161 aggcccagca gccggtaccg gccctggatc agtgtgctct ccctcatcgc gcgctgccgc
    20221 cccctctcgc ccgtgccgcc ccccggcccg cccagtatgg gccctttccc gaccgtgcgg
    20281 taaggcggca gggcggtcga tcggcgccgg gtgtgccggt gcgcaccgga gcgccaccgc
    20341 cgggtgcacc ggggtttcgg cacgtgcgat gcggcaactg cggaccggga cggttcgccc
    20401 ggaacgtgcc ggcggacccc gccgggaaga gggaggcgcc gatgtcccga cccgtgcccc
    20461 tgcgcgtacg cggcagccgg gcgggcttcc ggcagctcgc ccggctgcgc cacgcccccg
    20521 ccttccaccc cgatggcctg acctgcaccg gtgagctgac gatgcccggt ccccggggga
    20581 ccgcctgggg cgtcccctgg ctggacgggc tcggccggta cgagtgcgtg gtacggctgt
    20641 cccggggcgc cggcctgccg cggccgctgc ccgactggct cgggctcgcc gtccgggtgc
    20701 tggacgcggg cggccccggc cggcccgtgg acctgctgct gaccagcagc gcccggcccc
    20761 ccgtgctgcg ccggctgccc ctgccgcgcg gcgacgcgct gggcggcccg tacagcagcc
    20821 tgctcaccta ccgggtcggc gggcgcgaca tggtgctggc cgccttcccg cgccgccggc
    20881 tgcgcccggt ccacggcagc cctcccgccc tgcggcgggc gctcgcggac gggccgctgg
    20941 tgttcgacct gcgggcggcc gagccggcgg gccggtggcg gaccttcgcg gtgctcaccg
    21001 tccgctcgcc gctgcgggag ccgccccgtt ccaccccggg cttcgacgtc caccgaaaca
    21061 gcctgccgga gctggcgccg ggcacggcct tcgcggcggt gcggcccgcg
//
