LOCUS       NZ_FOBB01000020        13773 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga rupis strain DSM 21039, whole genome shotgun sequence.
ACCESSION   NZ_FOBB01000020
VERSION     NZ_FOBB01000020.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga rupis
  ORGANISM  Chitinophaga rupis
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900109685.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 15:41:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,474
            CDSs (total)                      :: 6,410
            Genes (coding)                    :: 6,392
            CDSs (with protein)               :: 6,392
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 18
            CDSs (without protein)            :: 18
            Pseudo Genes (ambiguous residues) :: 0 of 18
            Pseudo Genes (frameshifted)       :: 4 of 18
            Pseudo Genes (incomplete)         :: 13 of 18
            Pseudo Genes (internal stop)      :: 2 of 18
            Pseudo Genes (multiple problems)  :: 1 of 18
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:12:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 13773
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOBB01000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..13773
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>13773](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..>13773)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(<1..4030)
                     /locus_tag="BMZ54_RS32630"
                     /old_locus_tag="SAMN04488505_1201"
     CDS             complement(<1..4030)
                     /NRPS_PKS="Domain: AMP-binding (258-652). E-value:
                     7.9e-109. Score: 355.9. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32630_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (759-828). E-value: 5.3e-20. Score:
                     63.4. Matches aSDomain: nrpspksdomains_BMZ54_RS32630_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (864-1165). E-value:
                     6.7e-57. Score: 184.8. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32630_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="BMZ54_RS32630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_1201"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_143081226.1"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-116, bitscore:
                     375.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-19, bitscore:
                     58.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.8e-44, bitscore:
                     140.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVDNAVFTGSRYQPYIAYWKQLLQRHAHTCRQAVRPPDESNCS
                     TFTFRLSREDAPPLFALGAGNRTALMLNLLSAFAVVCSRYSSRETVIIDTPLHNNSTAP
                     KYAAKVPLLLTVDAKATLHEYLSTCQRTVRDAYRFQDFPASLLETYGKASTDIFFSFED
                     WHLPATAAGGYALVIHAAQKGDELEVMLQGDAEAFEPLFLEHMKQHICAVLNAMANLQR
                     TLAQVTLLSEDAARQLLDTYSGTTAVYPVDETITTLFERQAAATPQHTAVIAGSSSLSY
                     AALNAAANQLAHGLRGEYGVQHGDVVAIVTDRSELVVIAMLAILKAGATYLPVESTLPE
                     ERIRYMLQDAGAKLLVTGSRQMLQAAAYFSGPLFVLDIQLAALTTPAANLPPAATPASA
                     AYIIYTSGTTGYPKGVVIPHAAQVNMCYGQMERFGITAADKILQSASLSFDVCGFEIFM
                     ALYAGATVVIADRDLVNDGTALLQYMQQHQVTVAAFTASYLQVLPVMELYSLRVLITGG
                     EAVHAATLAALPANVQFHNAYGPTECTVCAATYNISAGTEAYWPVPLGKPLPNIRMYIL
                     DQQLQPVPAGMKGELCISGICLANGYLGQPELTAEKFVPHPFLPGERLYRTGDVARWLP
                     DGNVVYCGRMDGQVKINGNRVETAEIEAVLMLQPGITKVLVLPLTENERTQLAAYIQAV
                     GELDEDQLKEKLSALLPAYMVPAFFIPLKEFPLTANGKVDTAALPSPRQPATEAAVAYE
                     APANDTEEKLCNLWKEILRKETIGVTENFFSLGGDSLKAIQMVTAINRLFGRPVPVDKI
                     YTGPTIRELAAFLGQDAGASSLYHDLEKGTLLLEDFARRITAENKEALPAGYEDLYPVT
                     PIEAGMIYSSLLEPEKPVYYDQYNFQLELSSFALFESAFTFLAHRHPMLRTFFFMSGFS
                     EPLKVVVRNPTLPVTMEDLSHHPYDTQLQLVKEYLQADRNNRFHFDGELLWRLKAFRLS
                     EKQFYIVWSTHHAMLDGWGKNQLKTEMGKLLAGNNGLLDMQALQPLKYSYRDYCAITLG
                     RKYTEAAKHYWQQTLDGSIRNRLPFNYAGKQLNDDKSMPVQAKILDRELLNKLELMCKE
                     QQVSFKALAMAAFAYLMHILCAEEDVITGVVSHDRPALEDSDKILGCFLTTIPVRLQVK
                     EAHDYLSLITLAQQYLLDVKPHEMHLTDIAKVTGIQTTAHSPFFSCMLNYTDFFVLEEY
                     EDSDNMSLQRYFQEDAALLDFGMTNTLLDIEIGKTTQTLGISIRYRAAYFREEDMKYAL
                     EIYERILRNIAADVRQPLHTAALMDGATQRWLTYDFNNTLHPYDDSIRLESLLSRQAAV
                     "
     source          1..13773
                     /db_xref="taxon:573321"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070597_120"
                     /organism="Chitinophaga rupis"
                     /strain="DSM 21039"
                     /type_material="type strain of Chitinophaga rupis"
     region          1..13773
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="transAT-PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="(cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or
                     ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or
                     cds(tra_KS and PP-binding)))"
                     /tool="antismash"
     cand_cluster    1..13773
                     /SMILES="NC(CC(=O)N)C(=O)CC(O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /kind="interleaved"
                     /product="NRPS"
                     /product="transAT-PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..13773
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[4042:10378](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /neighbourhood="20000"
                     /product="transAT-PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(4043..10378)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /neighbourhood="20000"
                     /product="transAT-PKS"
                     /protocluster_number="2"
     aSDomain        complement(536..1438)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32630_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.70E-57"
                     /label="BMZ54_RS32630_Condensation_DCL.1"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="1165"
                     /protein_start="864"
                     /score="184.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAMLDG"
                     /tool="antismash"
                     /translation="EDLYPVTPIEAGMIYSSLLEPEKPVYYDQYNFQLELSSFALFESA
                     FTFLAHRHPMLRTFFFMSGFSEPLKVVVRNPTLPVTMEDLSHHPYDTQLQLVKEYLQAD
                     RNNRFHFDGELLWRLKAFRLSEKQFYIVWSTHHAMLDGWGKNQLKTEMGKLLAGNNGLL
                     DMQALQPLKYSYRDYCAITLGRKYTEAAKHYWQQTLDGSIRNRLPFNYAGKQLNDDKSM
                     PVQAKILDRELLNKLELMCKEQQVSFKALAMAAFAYLMHILCAEEDVITGVVSHDRPAL
                     EDSDKILGCFLTTIPVRLQV"
     CDS_motif       complement(545..637)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0008"
                     /evalue="2.40E-06"
                     /label="C5_DCL_263-294"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="1162"
                     /protein_start="1131"
                     /score="20.0"
                     /tool="antismash"
                     /translation="DVITGVVSHDRPALEDSDKILGCFLTTIPVR"
     CDS_motif       complement(1259..1294)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0007"
                     /evalue="2.60E-03"
                     /label="Cy2"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="924"
                     /protein_start="912"
                     /score="10.5"
                     /tool="antismash"
                     /translation="LAHRHPMLRTFF"
     aSDomain        complement(1547..1753)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32630_PCP.1"
                     /evalue="5.30E-20"
                     /label="BMZ54_RS32630_PCP.1"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="828"
                     /protein_start="759"
                     /score="63.4"
                     /tool="antismash"
                     /translation="EEKLCNLWKEILRKETIGVTENFFSLGGDSLKAIQMVTAINRLFG
                     RPVPVDKIYTGPTIRELAAFLGQD"
     aSModule        complement(1547..5440)
                     /complete
                     /domains="nrpspksdomains_BMZ54_RS32635_Condensation_LCL.1"
                     /domains="nrpspksdomains_BMZ54_RS32630_AMP-binding.1"
                     /domains="nrpspksdomains_BMZ54_RS32630_PCP.1"
                     /locus_tags="BMZ54_RS32630"
                     /locus_tags="BMZ54_RS32635"
                     /monomer_pairings="X -> X"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2045..2110)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0006"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="662"
                     /protein_start="640"
                     /score="29.5"
                     /tool="antismash"
                     /translation="YCGRMDGQVKINGNRVETAEIE"
     aSDomain        complement(2075..3256)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32630_AMP-binding.1"
                     /evalue="7.90E-109"
                     /label="BMZ54_RS32630_AMP-binding.1"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="652"
                     /protein_start="258"
                     /score="355.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FERQAAATPQHTAVIAGSSSLSYAALNAAANQLAHGLRGEYGVQH
                     GDVVAIVTDRSELVVIAMLAILKAGATYLPVESTLPEERIRYMLQDAGAKLLVTGSRQM
                     LQAAAYFSGPLFVLDIQLAALTTPAANLPPAATPASAAYIIYTSGTTGYPKGVVIPHAA
                     QVNMCYGQMERFGITAADKILQSASLSFDVCGFEIFMALYAGATVVIADRDLVNDGTAL
                     LQYMQQHQVTVAAFTASYLQVLPVMELYSLRVLITGGEAVHAATLAALPANVQFHNAYG
                     PTECTVCAATYNISAGTEAYWPVPLGKPLPNIRMYILDQQLQPVPAGMKGELCISGICL
                     ANGYLGQPELTAEKFVPHPFLPGERLYRTGDVARWLPDGNVVYCGRMDGQVKIN"
     CDS_motif       complement(2192..2281)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0005"
                     /evalue="4.00E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="613"
                     /protein_start="583"
                     /score="44.7"
                     /tool="antismash"
                     /translation="PAGMKGELCISGICLANGYLGQPELTAEKF"
     CDS_motif       complement(2393..2419)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0004"
                     /evalue="2.90E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="546"
                     /protein_start="537"
                     /score="10.3"
                     /tool="antismash"
                     /translation="YGPTECTVC"
     CDS_motif       complement(2627..2653)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0003"
                     /evalue="5.50E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="468"
                     /protein_start="459"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="LYAGATVVI"
     CDS_motif       complement(2774..2833)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0002"
                     /evalue="3.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="419"
                     /protein_start="399"
                     /score="28.6"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGYPKGVVIPH"
     CDS_motif       complement(3029..3067)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32630_0001"
                     /evalue="3.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="BMZ54_RS32630"
                     /protein_end="334"
                     /protein_start="321"
                     /score="14.1"
                     /tool="antismash"
                     /translation="LAILKAGATYLPV"
     gene            complement(4043..9448)
                     /locus_tag="BMZ54_RS32635"
                     /old_locus_tag="SAMN04488505_1202"
     CDS             complement(4043..9448)
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (5-420). E-value:
                     9.1e-140. Score: 458.2. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32635_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KR (968-1160). E-value: 1.4e-42.
                     Score: 137.6. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32635_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1249-1314). E-value: 1.2e-18.
                     Score: 59.0. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32635_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1336-1637). E-value:
                     9.5e-96. Score: 312.3. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32635_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="BMZ54_RS32635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_1202"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_089921456.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.9e-62, bitscore:
                     197.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 3.2e-144, bitscore:
                     468.9, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.9e-40, bitscore:
                     125.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.2e-17, bitscore:
                     51.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.6e-76, bitscore:
                     244.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKDIAIIGIAGRFPHAKDMEQFYLQLRNGKDCVGPLSEQRIRS
                     TTLEDDVEYDEGGYIEGIELFDHEFFKISQGEANHMDPRQRLLLEVVYETMENAGYNTD
                     HFNNSDTALYVADNNLNYYLHAEEVDATLMMGNLSAATAGRIARFFNLRGSAEMVDTAC
                     SSSLAVLNHACNELILGNADYALACGANVYVFPGIKVAARSGLEIRSPDSRARAFAAGA
                     NGTVEGEAVVCVLLKPLEKALADKDVIHAVIKAVASNQDGALSSSLTAPDSKAQAQVIT
                     KAWKKANIDPATVTYIEAHGTGTKLGDPIEIDGLNMAFREFTDKQHFCAVSSVKTNIGH
                     TDVVAGLAGVAKAVLSLHKKELFPSLHFDAPNPYIDFNKSAVYVNTTLQPWPEGNSPRR
                     AGVSSYGLIGTNYHAVLEEAPELPATAVVTEGVPYLFNLSAASLTSLCDTAKELYSYLC
                     DHNPLLQDISYTLNAGRKQHRYRCSFIADNKAQLLQALDDIAAGRSLPITATAVNMICC
                     FSASANVPASMLDACSEQYPEFARARYACGQAVAGGTTDAAYRQFVFQYAFYQLLTARG
                     VTSLQLLGDGVGKLVIAVLKQEITLQEGIRRVLNREWTPVLPEALFERLRKYVEKEQPG
                     STLFAGMEPTGDITAALQEIFKAQGSGMVISPAEQEPDCLLPFIQQLYLAGIAVDWNHF
                     YGDVQVKRVVLPAYRFQLKRCWIKEIPVMQVEKSFYGMQWTPQPLPAAEREKAAGPLLV
                     VMDEKGLGEILVKRLQAAGHTCIGIRYRTAFRETDHTNFEINPASRDDFAALRTAVRER
                     FPAIGGIIYLANYGTHVTVTAANADALLEKGLYALLLLMQAFWYELDDKQVDLLTVSAN
                     AHAVLPGEKVRMPLGVMPEIFAKGVSLEFPRLHVKGIDLDAEDVDLEAAAAYILQEWEA
                     DTLPRFAAIRQGSRWVPNLLALAAEDLAAARPVHIKPGGVYLVTGGAGGIGLEVCKSLA
                     ARNKVQLIIFGRKQLPAPEEWAAYSGEQAATVKELLVLLASGSTVWYHALDVADPQQVT
                     AAFTAITARHQQLDGIFHAAGVFEKGYPLPDWTLEQFGRALAPKVKGSLLLAEHSRALQ
                     PGFIVFFSSVNAIAIPACNTDYAAANAFQDAFAAGSFPEGTQAVSINWPGWADTGMLFR
                     SGHVDKAGYLKNISTQEGIDILYKAMSAGRQQVAVLPFNKKAGAVILEDNPFFLAGAEQ
                     EKPESAPAPVAPAVPPVAEADTASTVRRIWYEVLQSENISDNDDFFDLGGHSLNGMQVI
                     NKLNKIYGTALDFEILLDYATVSTLAAYIDDWLAQHNNTVVENKDIMPAPVQDAYDLSY
                     AQKKLWLFDQVEKDKQPYIMPEAYFIGMALNEDAMCKAVETVVERHESLRTVFIVKDGE
                     PKQKVRSFEESGFTCMYMDLNGYADAEERIKLQTAAHAQLPFDLAKGPLIRVTLIKRSE
                     DAYVILIAVHHIIADAWSMDVIVDEVLQCYYAYEQGMSNPLAPLRIQYKDYVVWQQQQR
                     SSGKWDAHRSFWLQTLQGTLPVLQLPLDMERGSLQTFRGADVTLQVDAAVLSGLKQLCQ
                     EQDTTLFVVLLAAYTALLHRYSGQYDLLLASPVAGRKHEDLTSQVGFYINTLLVRTKLT
                     DNMSFAALVQQTRQYMIQALLHDDYPFDLLVKDLQVERVTNRSLLIDSGFSWLTAHTGA
                     AVQPLYNIQRLEDEVVAAKYDLWLYGTEVADGILFKLEYNCDLFKASSMQLFAERWASL
                     IMQIVKQPDILLNDIIMDSMLLHDEAETMPYAGDSFDFEYPLGNS"
     CDS_motif       complement(4406..4489)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0010"
                     /evalue="4.20E-08"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1681"
                     /protein_start="1653"
                     /score="25.5"
                     /tool="antismash"
                     /translation="MIQALLHDDYPFDLLVKDLQVERVTNRS"
     aSDomain        complement(4538..5440)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32635_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.50E-96"
                     /label="BMZ54_RS32635_Condensation_LCL.1"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1637"
                     /protein_start="1336"
                     /score="312.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIADA"
                     /tool="antismash"
                     /translation="DAYDLSYAQKKLWLFDQVEKDKQPYIMPEAYFIGMALNEDAMCKA
                     VETVVERHESLRTVFIVKDGEPKQKVRSFEESGFTCMYMDLNGYADAEERIKLQTAAHA
                     QLPFDLAKGPLIRVTLIKRSEDAYVILIAVHHIIADAWSMDVIVDEVLQCYYAYEQGMS
                     NPLAPLRIQYKDYVVWQQQQRSSGKWDAHRSFWLQTLQGTLPVLQLPLDMERGSLQTFR
                     GADVTLQVDAAVLSGLKQLCQEQDTTLFVVLLAAYTALLHRYSGQYDLLLASPVAGRKH
                     EDLTSQVGFYINTLLVRTKL"
     CDS_motif       complement(4547..4636)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0009"
                     /evalue="1.70E-08"
                     /label="C5_LCL_267-296"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1634"
                     /protein_start="1604"
                     /score="26.9"
                     /tool="antismash"
                     /translation="DLLLASPVAGRKHEDLTSQVGFYINTLLVR"
     CDS_motif       complement(4892..4927)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0008"
                     /evalue="5.90E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1519"
                     /protein_start="1507"
                     /score="9.5"
                     /tool="antismash"
                     /translation="QYKDYVVWQQQQ"
     CDS_motif       complement(4976..5041)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0007"
                     /evalue="4.00E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1491"
                     /protein_start="1469"
                     /score="32.2"
                     /tool="antismash"
                     /translation="VHHIIADAWSMDVIVDEVLQCY"
     CDS_motif       complement(5261..5368)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0006"
                     /evalue="1.20E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1396"
                     /protein_start="1360"
                     /score="33.8"
                     /tool="antismash"
                     /translation="YIMPEAYFIGMALNEDAMCKAVETVVERHESLRTVF"
     aSDomain        complement(5507..5701)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32635_PCP.1"
                     /evalue="1.20E-18"
                     /label="BMZ54_RS32635_PCP.1"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1314"
                     /protein_start="1249"
                     /score="59.0"
                     /tool="antismash"
                     /translation="TVRRIWYEVLQSENISDNDDFFDLGGHSLNGMQVINKLNKIYGTA
                     LDFEILLDYATVSTLAAYID"
     aSModule        complement(5507..9433)
                     /complete
                     /domains="nrpspksdomains_BMZ54_RS32635_PKS_KS.1"
                     /domains="nrpspksdomains_BMZ54_RS32635_PKS_KR.1"
                     /domains="nrpspksdomains_BMZ54_RS32635_PCP.1"
                     /locus_tags="BMZ54_RS32635"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(5969..6544)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32635_PKS_KR.1"
                     /evalue="1.40E-42"
                     /label="BMZ54_RS32635_PKS_KR.1"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1160"
                     /protein_start="968"
                     /score="137.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLVTGGAGGIGLEVCKSLAARNKVQLIIFGRKQLPAPEEWAAY
                     SGEQAATVKELLVLLASGSTVWYHALDVADPQQVTAAFTAITARHQQLDGIFHAAGVFE
                     KGYPLPDWTLEQFGRALAPKVKGSLLLAEHSRALQPGFIVFFSSVNAIAIPACNTDYAA
                     ANAFQDAFAAGSFPEGTQAVSINWPGWAD"
     CDS_motif       complement(6026..6121)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0005"
                     /evalue="2.20E-07"
                     /label="PKSI-KR_m4"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1141"
                     /protein_start="1109"
                     /score="23.4"
                     /tool="antismash"
                     /translation="FIVFFSSVNAIAIPACNTDYAAANAFQDAFAA"
     CDS_motif       complement(6446..6541)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0004"
                     /evalue="9.40E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="1001"
                     /protein_start="969"
                     /score="34.3"
                     /tool="antismash"
                     /translation="VYLVTGGAGGIGLEVCKSLAARNKVQLIIFGR"
     aSDomain        complement(8189..9433)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32635_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="9.10E-140"
                     /label="BMZ54_RS32635_PKS_KS.1"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="420"
                     /protein_start="5"
                     /score="458.2"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAIIGIAGRFPHAKDMEQFYLQLRNGKDCVGPLSEQRIRSTTLED
                     DVEYDEGGYIEGIELFDHEFFKISQGEANHMDPRQRLLLEVVYETMENAGYNTDHFNNS
                     DTALYVADNNLNYYLHAEEVDATLMMGNLSAATAGRIARFFNLRGSAEMVDTACSSSLA
                     VLNHACNELILGNADYALACGANVYVFPGIKVAARSGLEIRSPDSRARAFAAGANGTVE
                     GEAVVCVLLKPLEKALADKDVIHAVIKAVASNQDGALSSSLTAPDSKAQAQVITKAWKK
                     ANIDPATVTYIEAHGTGTKLGDPIEIDGLNMAFREFTDKQHFCAVSSVKTNIGHTDVVA
                     GLAGVAKAVLSLHKKELFPSLHFDAPNPYIDFNKSAVYVNTTLQPWPEGNSPRRAGVSS
                     YGLIGTNYHAVLEEAP"
     CDS_motif       complement(8516..8563)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0003"
                     /evalue="9.60E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="311"
                     /protein_start="295"
                     /score="14.2"
                     /tool="antismash"
                     /translation="YIEAHGTGTKLGDPIE"
     CDS_motif       complement(8639..8668)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0002"
                     /evalue="2.10E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="270"
                     /protein_start="260"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="DGALSSSLTA"
     CDS_motif       complement(8945..8989)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32635_0001"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="BMZ54_RS32635"
                     /protein_end="168"
                     /protein_start="153"
                     /score="11.5"
                     /tool="antismash"
                     /translation="GSAEMVDTACSSSLA"
     gene            complement(9452..10378)
                     /locus_tag="BMZ54_RS32640"
                     /old_locus_tag="SAMN04488505_1203"
     CDS             complement(9452..10378)
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (8-292). E-value: 2.1e-62. Score:
                     203.1. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32640_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.5"
                     /locus_tag="BMZ54_RS32640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_1203"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_089921457.1"
                     /sec_met_domain="PKS_AT (E-value: 1.4e-63, bitscore: 203.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTERLALLFPGGGTQYPGMGKTLYDASKMVKELFEEANDILGFN
                     LRRICFEGTLSALSAMNIAQPAIFTVSLAAAKVWMQDTGIRPAFACGHSLGELTALTAA
                     GVFSFEDALLLVHARGILLSEAGQQLNAGMMAVNKAPAGVVEAACKALNSEGAQVYVAV
                     YNSPLQQVVAGNRDDMALLANRLQAAGAETVLLQINTPSHCPLMATAGHRFRENINACT
                     HGAFSFPVISNVTAAPYTADTDITEMLTRHMTNPVRWADSITYLAAQDITTAVETPPQA
                     VLKQLMPYITPDISVYALDVAEDLIKI"
     aSDomain        complement(9503..10354)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32640_PKS_AT.1"
                     /evalue="2.10E-62"
                     /label="BMZ54_RS32640_PKS_AT.1"
                     /locus_tag="BMZ54_RS32640"
                     /protein_end="292"
                     /protein_start="8"
                     /score="203.1"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGGGTQYPGMGKTLYDASKMVKELFEEANDILGFNLRRICFEG
                     TLSALSAMNIAQPAIFTVSLAAAKVWMQDTGIRPAFACGHSLGELTALTAAGVFSFEDA
                     LLLVHARGILLSEAGQQLNAGMMAVNKAPAGVVEAACKALNSEGAQVYVAVYNSPLQQV
                     VAGNRDDMALLANRLQAAGAETVLLQINTPSHCPLMATAGHRFRENINACTHGAFSFPV
                     ISNVTAAPYTADTDITEMLTRHMTNPVRWADSITYLAAQDITTAVETPPQAVLKQLMPY
                     ITP"
     CDS_motif       complement(9695..9757)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32640_0006"
                     /evalue="1.20E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="BMZ54_RS32640"
                     /protein_end="228"
                     /protein_start="207"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="ATAGHRFRENINACTHGAFSF"
     CDS_motif       complement(9767..9787)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32640_0005"
                     /evalue="6.70E+00"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="BMZ54_RS32640"
                     /protein_end="204"
                     /protein_start="197"
                     /score="0.7"
                     /tool="antismash"
                     /translation="INTPSHC"
     CDS_motif       complement(9857..9895)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32640_0004"
                     /evalue="2.90E-02"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="BMZ54_RS32640"
                     /protein_end="174"
                     /protein_start="161"
                     /score="7.9"
                     /tool="antismash"
                     /translation="AVYNSPLQQVVAG"
     CDS_motif       complement(10010..10129)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32640_0003"
                     /evalue="5.80E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="BMZ54_RS32640"
                     /protein_end="123"
                     /protein_start="83"
                     /score="57.0"
                     /tool="antismash"
                     /translation="GIRPAFACGHSLGELTALTAAGVFSFEDALLLVHARGILL"
     CDS_motif       complement(10142..10198)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32640_0002"
                     /evalue="1.00E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="BMZ54_RS32640"
                     /protein_end="79"
                     /protein_start="60"
                     /score="12.3"
                     /tool="antismash"
                     /translation="MNIAQPAIFTVSLAAAKVW"
     CDS_motif       complement(10304..10351)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32640_0001"
                     /evalue="5.80E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="BMZ54_RS32640"
                     /protein_end="25"
                     /protein_start="9"
                     /score="15.7"
                     /tool="antismash"
                     /translation="FPGGGTQYPGMGKTLY"
     gene            complement(10399..>13773)
                     /locus_tag="BMZ54_RS32645"
                     /old_locus_tag="SAMN04488505_1204"
     CDS             complement(10399..>13773)
                     /NRPS_PKS="Domain: PCP (1-55). E-value: 8.9e-14. Score:
                     43.5. Matches aSDomain: nrpspksdomains_BMZ54_RS32645_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (70-372). E-value:
                     1.5e-89. Score: 291.9. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32645_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (538-930). E-value: 2.5e-98.
                     Score: 321.3. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32645_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1039-1103). E-value: 9.8e-14.
                     Score: 43.3. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS32645_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="BMZ54_RS32645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_1204"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_143081227.1"
                     /sec_met_domain="Condensation (E-value: 4.1e-70, bitscore:
                     224.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.4e-106, bitscore:
                     342.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-11, bitscore:
                     33.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LQQIGIHDNFLELGAHSLNIGAFVNRLHHESHIRLGLRDVFSEPT
                     IAGLCKVAESRGLSLYEGIRPVAQQEHYALSHAQQRLWIQSLMADDKTAYNISGAYEIT
                     GALKQDVLQQVFEQLLQRYEILRTVFINAGSATRQKILLPAASGFALNYRNISGAQDPA
                     AEAKRMAAADTLAAFDLSAGPLWRATLLQLAAGHYVLVFTWHHIIADALSMMKLMGEII
                     ELYSALEEGRGNTLQPLAIQYKDYAVWQQQEAYIAAMQDHRQYWHQKLSGNLTVLEFPV
                     DVPRSESRTYKGGRSRQFLDDVTARNFLRFIQEQDVTLFMGFLALVQTLAYRYTGTEDI
                     ILGTTVAGREHRDLEEQIGFFVNNLVLRMEVDGSDSFEQLLSKTKNMALEAYEHQEYPF
                     DQLVGEKLSSRSAARSPFFDVLVECNNLSLDKQETAGLQHLQVTPFDSGVISSRYDLIF
                     RCFEGEGMLLEIEYNVQLYTENTINRMMEHMVNLLLHILQNRQAPLSKLPYMSAVETRQ
                     LLDFSSIQYQQLPATDVVTLLEKQLLQTPQLPALVSGTVSISYAEMHAAANKLARHLNN
                     TYHVQPGDRVAIMLNASAEMIIGLLGILKSGAAYVPVDPAFPAERKHSIAAEAEVKVLL
                     TDAQHMLSMDFYEGPVFALDVQLPFLDEEVTALQVPLQANDLAYILYTSGSTGKPKGVA
                     IGHGALVTYLSWAAAYYVDAHTSGHFSLFTPLTFDLTVTSIFCPLITGNTLYIEDADQP
                     LSETLRQVFSDAYPVEIVKLTPAHISLLPQLAITRSNIKKVIAGGDMLTHKHISILRNI
                     NPQIRIINEYGPTEATVGCIVKEISEETRILIGRPVTNTGAYILDNAMQLVPVGNTGEL
                     FLTGSNLAAGYFRRPDLTEQQFKQHLFGEQRLYRTGDLARWLPDGNIECLGRKDDQVKV
                     NGYRVELREIEERLVMCPGIQAAGVICKKQESADVLLAFVEAAEPLNVPSINQYLRQYL
                     PAYMLPAVITQVPALPLTANGKVNYKLLQEKAFALADTPQTIVPPRNTLDQELLGWWQA
                     LLEKDAVSITDNFFEIGGNSLRLILLFNKISQQYPDVKMSHLFNYPTIQLQSDFIDGLT
                     GDAAAESSAAGVKEISF"
     aSDomain        complement(10462..10653)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32645_PCP.2"
                     /evalue="9.80E-14"
                     /label="BMZ54_RS32645_PCP.2"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="1103"
                     /protein_start="1039"
                     /score="43.3"
                     /tool="antismash"
                     /translation="QELLGWWQALLEKDAVSITDNFFEIGGNSLRLILLFNKISQQYPD
                     VKMSHLFNYPTIQLQSDFI"
     aSModule        complement(10462..13560)
                     /complete
                     /domains="nrpspksdomains_BMZ54_RS32645_Condensation_LCL.1"
                     /domains="nrpspksdomains_BMZ54_RS32645_AMP-binding.1"
                     /domains="nrpspksdomains_BMZ54_RS32645_PCP.2"
                     /locus_tags="BMZ54_RS32645"
                     /monomer_pairings="Asn -> Asn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(10948..11013)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0009"
                     /evalue="3.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="941"
                     /protein_start="919"
                     /score="35.2"
                     /tool="antismash"
                     /translation="CLGRKDDQVKVNGYRVELREIE"
     aSDomain        complement(10981..12156)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32645_AMP-binding.1"
                     /evalue="2.50E-98"
                     /label="BMZ54_RS32645_AMP-binding.1"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="930"
                     /protein_start="538"
                     /score="321.3"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="EKQLLQTPQLPALVSGTVSISYAEMHAAANKLARHLNNTYHVQPG
                     DRVAIMLNASAEMIIGLLGILKSGAAYVPVDPAFPAERKHSIAAEAEVKVLLTDAQHML
                     SMDFYEGPVFALDVQLPFLDEEVTALQVPLQANDLAYILYTSGSTGKPKGVAIGHGALV
                     TYLSWAAAYYVDAHTSGHFSLFTPLTFDLTVTSIFCPLITGNTLYIEDADQPLSETLRQ
                     VFSDAYPVEIVKLTPAHISLLPQLAITRSNIKKVIAGGDMLTHKHISILRNINPQIRII
                     NEYGPTEATVGCIVKEISEETRILIGRPVTNTGAYILDNAMQLVPVGNTGELFLTGSNL
                     AAGYFRRPDLTEQQFKQHLFGEQRLYRTGDLARWLPDGNIECLGRKDDQVKV"
     CDS_motif       complement(11092..11181)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0008"
                     /evalue="2.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="893"
                     /protein_start="863"
                     /score="32.8"
                     /tool="antismash"
                     /translation="PVGNTGELFLTGSNLAAGYFRRPDLTEQQF"
     CDS_motif       complement(11680..11739)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0007"
                     /evalue="7.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="697"
                     /protein_start="677"
                     /score="30.7"
                     /tool="antismash"
                     /translation="AYILYTSGSTGKPKGVAIGH"
     CDS_motif       complement(11929..11970)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0006"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="614"
                     /protein_start="600"
                     /score="17.7"
                     /tool="antismash"
                     /translation="LGILKSGAAYVPVD"
     CDS_motif       complement(12508..12612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0005"
                     /evalue="4.70E-11"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="421"
                     /protein_start="386"
                     /score="35.0"
                     /tool="antismash"
                     /translation="MALEAYEHQEYPFDQLVGEKLSSRSAARSPFFDVL"
     aSDomain        complement(12655..13560)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32645_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.50E-89"
                     /label="BMZ54_RS32645_Condensation_LCL.1"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="372"
                     /protein_start="70"
                     /score="291.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIADA"
                     /tool="antismash"
                     /translation="EHYALSHAQQRLWIQSLMADDKTAYNISGAYEITGALKQDVLQQV
                     FEQLLQRYEILRTVFINAGSATRQKILLPAASGFALNYRNISGAQDPAAEAKRMAAADT
                     LAAFDLSAGPLWRATLLQLAAGHYVLVFTWHHIIADALSMMKLMGEIIELYSALEEGRG
                     NTLQPLAIQYKDYAVWQQQEAYIAAMQDHRQYWHQKLSGNLTVLEFPVDVPRSESRTYK
                     GGRSRQFLDDVTARNFLRFIQEQDVTLFMGFLALVQTLAYRYTGTEDIILGTTVAGREH
                     RDLEEQIGFFVNNLVLRMEVD"
     CDS_motif       complement(12667..12756)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0004"
                     /evalue="2.00E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="368"
                     /protein_start="338"
                     /score="42.7"
                     /tool="antismash"
                     /translation="DIILGTTVAGREHRDLEEQIGFFVNNLVLR"
     CDS_motif       complement(13012..13047)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0003"
                     /evalue="2.10E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="253"
                     /protein_start="241"
                     /score="13.9"
                     /tool="antismash"
                     /translation="QYKDYAVWQQQE"
     CDS_motif       complement(13096..13158)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0002"
                     /evalue="1.90E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="225"
                     /protein_start="204"
                     /score="17.3"
                     /tool="antismash"
                     /translation="HHIIADALSMMKLMGEIIELY"
     CDS_motif       complement(13381..13494)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BMZ54_RS32645_0001"
                     /evalue="6.40E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="130"
                     /protein_start="92"
                     /score="47.5"
                     /tool="antismash"
                     /translation="TAYNISGAYEITGALKQDVLQQVFEQLLQRYEILRTVF"
     aSDomain        complement(13606..13767)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS32645_PCP.1"
                     /evalue="8.90E-14"
                     /label="BMZ54_RS32645_PCP.1"
                     /locus_tag="BMZ54_RS32645"
                     /protein_end="55"
                     /protein_start="1"
                     /score="43.5"
                     /tool="antismash"
                     /translation="QQIGIHDNFLELGAHSLNIGAFVNRLHHESHIRLGLRDVFSEPTI
                     AGLCKVAES"
ORIGIN
        1 taacagcagc ctgcctgctt aacaggctct ccagccggat actatcatca tagggatgca
       61 gtgtgttgtt aaaatcgtaa gtgagccagc gctgtgttgc accatccatt aaggcggctg
      121 tatgtaaggg ctggcgtaca tccgcagcta tattgcgcag gatgcgctca tatatttcca
      181 gcgcatactt catatcctcc tcacggaaat aggcagcgcg gtaacggatg gaaattccca
      241 gcgtctgcgt ggttttaccg atctctatat ccagcagcgt attggtcatt ccaaaatcca
      301 gcagcgctgc atcttcctgg aagtaccgct gcagcgacat attatcactg tcctcatatt
      361 cttccagcac aaaaaagtca gtatagttaa gcatacagct aaagaagggc gagtgtgcgg
      421 tagtttgtat gcctgttacc tttgcgatat ccgttaagtg catttcatgc ggctttacat
      481 ccagcaaata ctgttgtgcc agcgttatga gcgaaaggta atcatgtgcc tcctttacct
      541 gcaaacgtac aggtatggtt gtcaggaaac atcccagtat tttatcactg tcttccagtg
      601 caggccggtc gtgggatacc acgccggtta ttacatcctc ctctgcgcaa agtatatgca
      661 tcaggtaagc aaatgccgcc atagccaatg ccttgaacga cacttgctgc tctttgcaca
      721 tcagttccag cttattcaac agctcacggt ccaggatctt tgcctgtacc ggcatgcttt
      781 tgtcgtcatt cagctgcttg cctgcataat taaagggcag gcggttacgt atggagccgt
      841 ccagcgtttg ctgccagtag tgcttagcgg cttctgtata cttacggccc aatgtaatgg
      901 cgcaataatc acggtagctg tatttcagcg gctgcagggc ctgcatatcc aggaggccgt
      961 tgttgccggc cagcagcttt cccatttctg ttttcagctg gttcttgccc catccgtcca
     1021 gcatagcatg gtgtgtagac catactatat aaaattgttt ttccgaaaga cggaatgctt
     1081 taaggcgcca caataattca ccgtcaaaat ggaaacggtt attacggtcg gcctgcaaat
     1141 attcttttac cagctgcagc tgtgtgtcat aggggtgatg actgagatct tccatagtaa
     1201 caggcagcgt gggattgcgt actaccactt ttaagggctc actgaagccg ctcataaaaa
     1261 agaaggtacg cagcatggga tggcggtgcg ccaggaaggt gaatgcgctt tcaaaaagtg
     1321 caaagctgct cagctccagc tgaaagttat actggtcata atacaccggc ttttcaggtt
     1381 ccagcaaaga ggaatagatc atgccggctt ctatgggtgt tacggggtac agatcttcat
     1441 atcctgccgg taaagcttcc ttattttctg ctgtgatcct gcgtgcaaaa tcttccagca
     1501 acagggtacc tttttcaagg tcatggtaaa gtgatgatgc gcctgcatcc tggcctaaaa
     1561 aggcggccag ctcacggatc gtgggacccg tatagatctt gtctaccggt accggacggc
     1621 cgaacaggcg gttaatggcc gttaccatct ggatggcttt taaggaatcg cctcccaggg
     1681 aaaagaagtt ttccgttacg ccaatggtct ctttccgcaa gatctctttc cataagttac
     1741 agagcttttc ttctgtatca ttggccggcg cttcataggc aacagctgct tccgttgccg
     1801 gttgccgggg tgatggcagc gctgccgtat ctacctttcc gttagcggtt aacggaaatt
     1861 ctttcagggg tataaaaaat gctggcacca tgtaagccgg caacaaagcg gataatttct
     1921 ctttcagctg atcctcgtct aattcaccaa cagcctgtat gtatgcagcc agctgcgtgc
     1981 gttcattttc cgttaacggt agcaccagca cttttgtaat gcctggctgc agcataagca
     2041 ctgcttctat ttcagcggtt tctacgcggt tgccatttat tttcacctgg ccatccatac
     2101 ggccgcagta taccacattt ccatccggca gccagcgtgc aacatcgccc gtgcggtata
     2161 atctttcacc cggcaggaac ggatgcggta caaacttttc tgcggttaac tccggctgcc
     2221 ccaggtaacc gtttgccagg caaatacctg aaatgcaaag ctctcccttc atgcctgccg
     2281 gtaccggctg cagctgctga tccaggatat acatcctgat attgggtagg ggcttgccca
     2341 ggggcaccgg ccaataggct tccgtgccgg cagagatatt gtaggtagca gcgcaaacgg
     2401 tacattccgt tggcccatac gcgttatgaa actgtacgtt cgccggcaaa gcagccaaag
     2461 tagctgcatg tacggcttca ccgcctgtaa taagcacccg caggctatag agctccatta
     2521 ccggtaatac ctgcaggtaa gatgcggtga aagcggctac ggttacctgg tgctgctgca
     2581 tatactgcag cagggctgtg ccatcattaa ccaggtcacg gtctgctatt accaccgtag
     2641 cgccggcata caatgccata aagatctcaa agccgcatac atcaaatgaa agagaggcgc
     2701 tttgtaagat cttatccgca gccgtgatgc caaaacgctc catttgcccg taacacatat
     2761 tcacctgcgc ggcatgcggt atcaccactc ctttgggata ccctgtggta cctgatgtat
     2821 aaataatata agccgcgctt gcaggcgttg ctgccggcgg caggttggcg gcgggtgttg
     2881 ttaaggcagc cagctgtata tccagcacaa aaagaggacc gctgaaatat gcagctgcct
     2941 gtaacatttg cctggagcct gttaccagca attttgcccc ggcatcctgc agcatataac
     3001 ggatacgttc ctccggtaaa gtactctcca caggcaggta cgttgcaccg gctttcagta
     3061 tggccagcat agcgatcact accagctccg aacggtctgt tacaatagcc actacatcgc
     3121 cgtgctgcac accatattcc ccgcgcaggc catgtgccag ctggtttgct gcggcattca
     3181 gcgctgcata tgacaggctg ctgctgcctg caattacagc tgtgtgctgc ggcgtagcag
     3241 cagcctgccg ttcaaacagt gtggtaatgg tttcatccac cgggtacacc gccgttgtgc
     3301 cgctgtaggt atccagcagc tgcctggcag catcttcgct aagtaatgtt acctgcgcaa
     3361 gggtacgctg caggttagcc attgcattca gcactgcgca tatatgctgt ttcatatgct
     3421 ccaggaaaag cggctcaaat gcctccgcat cgccctgaag cattacttcc agctcatccc
     3481 ctttttgtgc agcatgtatt accagcgcgt atccgcccgc tgcggttgcg ggcaaatgcc
     3541 agtcctcaaa gctgaagaat atatccgtag atgccttacc gtaagtttcc agcagggatg
     3601 ccggaaagtc ctgaaagcgg taagcgtcgc gaacagtgcg ctggcaggtg gataagtatt
     3661 catgtagtgt ggcttttgca tctaccgtta acagcagcgg cactttcgct gcatacttag
     3721 gcgccgtgct gttattatgc aaaggcgtat ctattatcac ggtttcgcgg ctgctgtaac
     3781 ggctgcatac cacagcaaag gcagacagca ggtttaacat gagcgccgtt ctgttgccgg
     3841 cccctaatgc aaaaagcggt ggcgcatctt cccgtgataa gcggaaggta aaggtgctgc
     3901 aattgctttc atccggcggg cgtacagcct ggcggcaggt atgcgcatgg cgctgcagca
     3961 attgcttcca atatgcaata taaggctggt accggcttcc ggtaaatacg gcattatcta
     4021 cagataacat tcaacgcggg aattaggagt taccaagtgg gtattcaaaa tcaaagctat
     4081 cgcctgcata cggcatggtt tccgcttcgt cgtgcaggag catggaatcc attataatat
     4141 cattcaataa aatatcgggc tgtttaacaa tttgcatgat cagcgacgcc catctttctg
     4201 cgaaaagctg catagaggat gctttaaaca gatcacagtt atattccagc ttaaacagga
     4261 tgccatccgc cacctctgtt ccatacagcc agagatcata tttagcggct accacctcat
     4321 cttccagccg ctgaatgttg tatagcggct gcactgcggc gccggtatgc gcggtaagcc
     4381 agctaaaccc gctatcaata agcagggaac ggtttgtaac gcgttccacc tgcaggtctt
     4441 tcaccagcag atcaaaagga taatcatcat gcagcaaagc ctggatcata tattgcctgg
     4501 tttgctgcac cagtgcggca aaggacatat tgtccgtcag ctttgttctg accagcaaag
     4561 tgttgatata aaaacctacc tggctggtaa ggtcttcgtg tttacggccg gctaccggtg
     4621 atgccagcaa tagatcatac tggccggaat aacggtgcag caatgctgta taggcagcga
     4681 gcagcactac aaacaaggtg gtatcctgtt cctggcaaag ctgctttaag ccgcttaata
     4741 cggctgcatc cacctgcagt gtaacatctg cgcccctgaa agtttgcagg ctgccacgct
     4801 ccatatccag cggcagctgt aatacaggta atgtgccctg caatgtttgc agccagaagc
     4861 tgcgatgtgc atcccatttg ccgctgctac gttgctgctg ctgccatacc acataatctt
     4921 tatactggat gcgcagcggg gccagcgggt tagacatgcc ctgttcataa gcataataac
     4981 attgcagcac ttcgtccaca atcacatcca ttgaccatgc atccgcaata atatggtgca
     5041 cggctattaa tataacatag gcatcttccg atcttttaat gagcgtaacc ctgatcagcg
     5101 ggcctttggc caaatcaaag ggcagctgcg catgcgctgc ggtttgcagc tttatacgct
     5161 cttctgcatc tgcgtaacca ttcaggtcca tgtacataca ggtaaacccg ctttcttcaa
     5221 agctgcgtac tttttgtttg ggttcgccat ctttaacaat aaatacggta cgcaggcttt
     5281 catgtctttc cacaaccgtt tcaactgcct tacacatcgc atcttcattt aacgccatgc
     5341 caatgaagta ggcttccggc ataatgtagg gctgcttatc tttttcaacc tggtcaaaca
     5401 accataactt cttttgcgca taggaaagat catatgcatc ctgtacaggg gcaggcataa
     5461 tatctttatt ctccacaacg gtgttattgt gctgcgccag ccagtcatct atataggcgg
     5521 ccagggtgct tacagtagca taatccagca gtatctcaaa gtccagcgcg gtgccgtaga
     5581 tcttattcag cttattaatg acctgcatgc cattcaatga gtggccaccc aggtcaaaga
     5641 aatcatcgtt gtccgatatg ttctctgact gcaatacttc ataccatatt ctgcgtacag
     5701 tggaagccgt atctgcttct gccaccggcg gcacagcagg cgccaccggc gcgggggcac
     5761 tttcaggttt ttcctgttca gcgcctgcca ggaaaaaggg attatcttcc aggatcacag
     5821 cgccggcctt tttgttaaaa ggcaatacgg caacctgctg ccggccggcg ctcatggcct
     5881 tgtaaagtat gtcaatacct tcctgtgtag aaatgttctt caggtatcct gctttatcta
     5941 catgaccgct gcggaaaagc atgccggtat ctgcccagcc aggccagtta atggatacag
     6001 cctgtgttcc ttccgggaag ctgccggcgg caaaggcatc ctggaacgca ttggcagctg
     6061 cgtaatctgt attacaggcg gggatagcaa ttgcattaac agaggagaaa aatacaatga
     6121 aaccgggctg cagtgcgcgg ctatgttctg ccaacaataa cgatcctttt actttaggcg
     6181 ccagcgccct gccgaattgc tccagcgtcc agtcaggcag cgggtaacct ttttcaaata
     6241 cacctgctgc atggaagatg ccatccagct gctgatgcct ggctgtaata gcggtaaaag
     6301 ctgccgttac ctgctgcgga tccgctacat ccaatgcatg ataccatact gttgaaccgg
     6361 atgccagcaa gactaacagc tcttttaccg ttgcagcctg ttcgccggaa taagcagccc
     6421 attcctcagg ggccggcagc tgctttcttc caaaaatgat cagctgtact ttattacggg
     6481 cggctaacga cttacaaact tccaggccaa taccgccggc accgccggta acaaggtata
     6541 cgccgcctgg ctttatgtga accggcctgg cagctgcaag atcttctgca gcaagcgcaa
     6601 gcaggtttgg cacccagcgg ctgccctggc ggatagcggc aaagcggggc agcgtatctg
     6661 cttcccattc ctgcaatata taagcggcag cagcttcaag gtcaacgtct tcagcatcga
     6721 ggtcaatgcc ctttacatgc agcctgggaa attccaggct tacacctttg gcaaatattt
     6781 ccggcatcac gcctaagggc atacgtactt tttcgccggg taacactgcg tgcgcattgg
     6841 cggagactgt taacaggtct acctgtttat catccagctc ataccagaat gcctgcataa
     6901 gcaataacag cgcatataaa cctttttcca gcagcgcatc tgcatttgcc gcggttaccg
     6961 ttacatgcgt gccgtaatta gccaggtata taataccgcc aatagccgga aaacgctccc
     7021 tgacagcggt acgcaaggct gcaaagtcat cccggctggc agggtttatt tcaaagtttg
     7081 tatgatctgt ttcacggaaa gctgttctat aacggatacc gatacacgtg tgacctgctg
     7141 cctgcagcct ttttaccagt atttcaccca ggcctttttc atccatcact accagcagcg
     7201 ggccggcagc tttttcacgt tctgcggccg gcagtggctg cggcgtccat tgcatcccgt
     7261 aaaagctttt ctctacctgc atcaccggta tttctttgat ccagcaacgt ttgagctgaa
     7321 agcggtaagc aggcaacact acgcgtttta cctgtacgtc cccgtaaaag tggttccagt
     7381 caacagctat gcctgccagg tatagctgct gtataaaagg aagtaagcaa tcaggctcct
     7441 gctcagcggg acttattacc ataccgcttc cctgcgcctt gaaaatctcc tgtaacgcgg
     7501 cggtaatgtc tcctgtcggt tccataccag caaagagggt gctgcccggc tgctcttttt
     7561 ctacgtattt gcgtaagcgt tcaaaaagcg cttccggcag aacgggcgtc cattcccggt
     7621 ttaatacccg gcggatacct tcctgcaaag tgatctcctg ttttaacacc gctatcacca
     7681 gtttgccaac cccatcgccc agcagctgca gggacgttac acctctggcg gttagcagct
     7741 gataaaaagc atattgaaat acaaattgcc ggtaagccgc atccgttgtg ccgccggcaa
     7801 ctgcctgacc gcatgcataa cgtgcacggg caaactccgg gtactgctca ctgcaggcat
     7861 ccagcatgga agccggaaca ttggcactgg cggaaaaaca gcaaatcata ttcaccgcag
     7921 tagcggtaat gggcaggctg cggccagccg caatatcgtc taacgcctgt aacagctgtg
     7981 ctttattgtc tgcaataaac gagcagcggt agcggtgctg cttacgtcct gcattcagtg
     8041 tatagctgat atcctgcagc aaggggttat ggtcacataa gtaactatat aattcctttg
     8101 ccgtatcaca caatgaagta agggacgctg ctgaaaggtt aaaaagataa ggcacccctt
     8161 ccgttactac cgcagttgcc ggcagctccg gcgcttcttc cagcactgca tgataattag
     8221 tgccaataag cccataggag cttacaccgg ccctacgcgg gctattgcct tccggccagg
     8281 gctgcagcgt tgtatttaca taaacagcgg acttattaaa atcaatatat gggttgggcg
     8341 catcaaaatg taatgaagga aaaagctctt tcttgtgcag cgacagcact gctttggcta
     8401 cccctgccaa accggccact acatccgtat gcccgatgtt tgtttttaca gaagatactg
     8461 cgcaaaaatg ctgcttgtct gtaaactcac gaaaggccat attcagtccg tcaatctcaa
     8521 tagggtcgcc cagcttagtg cccgtgccat gcgcctcaat gtaagtaacg gtggcaggat
     8581 ctatgttggc ttttttccat gcttttgtga tcacctgcgc ctgtgccttg ctatccggcg
     8641 ccgtaaggct gctggaaaga gcgccgtcct ggttggaggc tactgctttt attaccgcat
     8701 ggatcacatc tttatctgcc agcgcttttt ccaaaggttt cagcagcaca catactactg
     8761 cctccccttc cactgtaccg tttgcgccgg cagcaaaggc cctggcgcgg ctgtcggggg
     8821 agcggatctc caggccgctg cgtgcagcta cctttatgcc cggaaataca taaacatttg
     8881 caccacaggc cagcgcataa tctgcattgc ccaggatcag ctcattgcag gcatggttta
     8941 ataccgccag tgatgaagaa catgccgtat ccaccatttc cgcgctgccg cgcaggttaa
     9001 agaagcgggc aatacggccg gcggtggcgg cgctcaggtt acccatcatc agggtggcat
     9061 ccacctcctc tgcatgcagg taatagttca gattattatc tgccacatac agcgcggtgt
     9121 ctgaattatt gaagtgatct gtattgtaac ctgcattttc catggtttca tataccactt
     9181 ccagcaacag gcgctgacgg ggatccatat ggttagcctc tccctgggat attttaaaga
     9241 actcatggtc aaagagctca ataccttcta tataaccgcc ttcatcatat tccacatcgt
     9301 cctccagcgt ggtgctgcgg atgcgttgtt cgctcagcgg gcccacacaa tcctttccgt
     9361 tcctgagctg caggtaaaac tgctccatgt ccttcgcatg cgggaaccgg cctgctatac
     9421 ctattatggc aatatcttta gtggtcatgg tttaaatttt tatgaggtct tcggcaacat
     9481 ccagcgcata tacgctgatg tcaggggtta tataaggcat cagctgcttc agcactgcct
     9541 gcggcggggt ttccactgct gtggtaatat cctgtgctgc caggtatgtg atgctatctg
     9601 cccagcgtac agggttggtc atatgccgtg taagcatttc cgttatatcc gtatctgctg
     9661 tataaggcgc tgccgttaca tttgaaataa ccgggaaact aaaagcgccg tgggtgcagg
     9721 cgtttatatt ttcgcggaaa cggtggcctg ctgtggccat caacgggcaa tgcgatggtg
     9781 tattgatctg cagcagtacg gtttctgcac cggcggcctg cagcctgttt gccagcaggg
     9841 ccatatcatc ccggttaccg gccactacct gctgcagcgg tgaattatat acggctacgt
     9901 atacctgcgc gccttcgctg ttcaatgcct tacaagcagc ttccaccacg ccggcaggcg
     9961 ctttgttcac cgccatcata cctgcattca gctgctgccc ggcttctgat aataatatac
    10021 ctcttgcatg caccagcaat aaagcatctt caaaggaaaa cacaccggct gcagtaagcg
    10081 cagtaagctc gcccaaacta tgaccgcagg caaaagcagg ccgtataccg gtatcctgca
    10141 tccacacctt tgctgccgcc aggcttacgg taaatatggc cggctgcgca atgttcatgg
    10201 cagaaagggc agacaatgtg ccttcaaaac agatacggcg caggttgaac cctaaaatat
    10261 cattggcttc ttcaaacagc tctttcacca ttttactggc gtcatacagc gttttgccca
    10321 tacccgggta ttgtgtgccg ccaccgggga ataataatgc cagccgttca gttgtcatga
    10381 tgcaggtatg gtttataatt aaaaactgat ctcttttacg ccggcagcac tgctttcagc
    10441 tgctgcatca ccggtgagtc catcaataaa gtcgctttgc agctgaatgg tggggtagtt
    10501 gaacaggtgg ctcatcttca catcaggata ttgctggctg atcttattga acagcaggat
    10561 gagccgcaaa gagttaccgc ctatttcgaa gaagttatcc gtaatgctga ccgcatcctt
    10621 ttccagcagc gcctgccacc agcccagtag ctcctggtcc agcgtattcc ttggaggcac
    10681 aatagtttgc ggcgtatctg ccaatgcaaa ggctttttcc tgtagtaatt tataattcac
    10741 ttttccatta gccgtaagcg gtagggccgg tacctgcgtt ataacagcgg gcagcatgta
    10801 agcgggcagg tattgccgca ggtactggtt aatggacggt acattcaagg gttctgccgc
    10861 ttctacaaac gccagcagca catccgcgct ctcctgcttt ttgcagatca cgcctgctgc
    10921 ctgaataccg gggcacataa ccagccgctc ttctatttcc cgtagctcta cccggtagcc
    10981 atttaccttt acctggtcat ctttcctgcc caggcattca atattgccat ccggcagcca
    11041 gcgggccagg tcgcccgttc tgtataagcg ctgctcacca aaaaggtgct gtttgaattg
    11101 ctgctccgta agatccggcc ggcggaagta acctgctgcc aggttgctgc cggtgaggaa
    11161 aagctcgccg gtattgccaa ccggcaccag ctgcatggcg ttgtcgagta tataagcgcc
    11221 cgtattggta accgggcggc ctatcagtat acgcgtttct tcactgatct cttttacaat
    11281 acagcctact gtagcttctg ttggtccata ttcattaatg atacggatct gcggattgat
    11341 gttgcgcagt atggatatat gcttatgggt aagcatatcc ccgcccgcga tcactttctt
    11401 tatgttagag cgggtaatgg ccagctgcgg cagcaggcta atgtgcgcgg gtgtaagctt
    11461 tacgatctcc accgggtacg cgtcagaaaa aacctgccgc aatgtttcgc tcaatggctg
    11521 gtccgcatct tcaatgtata aagtattacc ggttatcagc ggacagaaaa tgctggttac
    11581 cgtaagatca aaagtaaggg gtgtaaacag gctaaagtgc ccgctggtat gcgcatcaac
    11641 ataataagcg gcagcccatg aaaggtaggt taccagggcc ccatgaccta ttgccacacc
    11701 tttgggcttg ccggtagaac cggaggtgta gaggatatat gccaggtcat ttgcctgcaa
    11761 cggcacctgt aatgcagtga cctcttcatc caggaacggc agctgcacat ccagcgcaaa
    11821 taccggccct tcataaaagt ccatggacag catatgctgc gcatctgtaa gcaatacctt
    11881 cacctcggct tccgctgcaa tgctgtgttt tctttctgcc gggaaagccg gatccaccgg
    11941 cacatatgca gcgccgcttt tgagaatacc cagcaaacca atgatcattt ctgcagaagc
    12001 attcagcata atggcaaccc ggtcgccggg ctgcacatgg tatgtgttat ttaggtggcg
    12061 cgccagctta ttggcggctg catgcatttc agcatagctg atgcttaccg taccgcttac
    12121 cagggcaggc agctgaggcg tttgcaacag ctgtttttcc agcagcgtta caacatcggt
    12181 tgcgggcagc tgctggtatt gtatgctgct aaaatccagc aactgcctgg tttccacagc
    12241 agacatataa ggcagcttag acaagggtgc ctgccggttc tgcagtatat gcagcaaaag
    12301 atttaccata tgctccatca tacggttaat ggtattttcc gtatagagct gtacgttata
    12361 ttcaatttcc agcagcattc cctcaccttc aaagcagcgg aatatgaggt cataacggct
    12421 gctgatgacg ccactatcaa acggcgttac ctgtaaatgc tgcaggccgg cggtttcctg
    12481 cttatccagt gaaaggttat tacattctac cagcacatca aagaagggag agcgtgccgc
    12541 gctgcgcgac gacagctttt cccctaccag ctgatcaaag ggatactcct ggtgctcata
    12601 ggcttccagg gccatatttt tcgttttgct taacagctgc tcaaaagaat cacttccatc
    12661 cacctccata cgcagcacca ggttatttac aaaaaagccg atctgttctt ccaggtctct
    12721 gtgctcacgc ccggcaaccg tggtaccaag aataatatct tctgtaccgg tataacggta
    12781 agccagcgtt tgcaccagcg ccaggaagcc catgaacaat gtaacatcct gctcctgtat
    12841 aaaacggaga aagttccgcg cagtaacatc atccaggaac tgacggctcc tgccgccttt
    12901 ataggtgcgg ctttcagaac ggggaacatc aaccggaaat tccagcacgg tcaaattgcc
    12961 cgacagcttt tgatgccagt actgccggtg atcctgcatt gcggcaatgt atgcttcctg
    13021 ctgctgccat acagcatagt ccttgtattg tatagccagc ggctgcaggg tatttcccct
    13081 tccttcttcc agcgcgctgt acagctcaat gatctctccc atcagcttca tcatagacaa
    13141 tgcatcggct ataatatgat gccaggtgaa tactagcaca taatgcccgg cagccagctg
    13201 cagtaaagta gcccgccata aaggaccggc ggaaagatca aatgctgcca gcgtatctgc
    13261 tgcagccatt ctttttgcct cagcagcagg atcctgcgcc ccgctgatgt tgcggtaatt
    13321 caaggcaaaa ccacttgctg caggcaataa tatcttttgc cgtgtagcgc tgccagcgtt
    13381 aatgaacact gtgcgtaata tttcataacg ctgtaataac tgctcaaata cctgctgcag
    13441 cacatcctgt tttaaagcac cggtgatctc atatgcgccg gaaatattgt aagctgtttt
    13501 atcatcagcc atcaggctct gtatccataa tctttgctgg gcatgtgaca gggcataatg
    13561 ctcctgctgc gctaccggac ggatgccttc gtaaaggctc agcccacgac tctctgccac
    13621 cttgcataaa cctgctatgg tgggctcgct gaacacatcc cgcaagccta aacgaatatg
    13681 gctttcatga tgcaaacggt tcacaaatgc gccgatgttc aaagagtgcg cccccagctc
    13741 aagaaaatta tcatggatgc ctatctgctg taa
//
