LOCUS       NZ_FOBB01000009        21110 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga rupis strain DSM 21039, whole genome shotgun sequence.
ACCESSION   NZ_FOBB01000009
VERSION     NZ_FOBB01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga rupis
  ORGANISM  Chitinophaga rupis
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900109685.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 15:41:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,474
            CDSs (total)                      :: 6,410
            Genes (coding)                    :: 6,392
            CDSs (with protein)               :: 6,392
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 18
            CDSs (without protein)            :: 18
            Pseudo Genes (ambiguous residues) :: 0 of 18
            Pseudo Genes (frameshifted)       :: 4 of 18
            Pseudo Genes (incomplete)         :: 13 of 18
            Pseudo Genes (internal stop)      :: 2 of 18
            Pseudo Genes (multiple problems)  :: 1 of 18
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:12:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 70021
            Orig. end                         :: 91131
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOBB01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21110
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21110
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21110
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11110](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11110
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    441..452
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 21.4"
                     /tool="antismash"
     gene            984..1772
                     /locus_tag="BMZ54_RS26285"
                     /old_locus_tag="SAMN04488505_10957"
     CDS             984..1772
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025053.5"
                     /locus_tag="BMZ54_RS26285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10957"
                     /product="protein phosphatase 2C domain-containing protein"
                     /protein_id="WP_143081140.1"
                     /transl_table=11
                     /translation="MAVYWKIKEICTFTFRMNVYSVLQIGEYHLNNCEDYLFYEPIGTD
                     KLLCAVMDGCTMGKDSYFIATLIGKLLRKIVKAKNYEEFYQLPFLELSLEEQLKVILKE
                     LFESLKNIKNELLLEKNEMLSTLTILIANLKDEQGVILVIGDGVICINGAITEFDQDNK
                     PDYVGYHLSENFEEWYDKQQQKIKFSGIKDISVATDGIMSFKSIEQKANLGDIDPVQYM
                     LNDTSKIEHEEMLNMKLKFLEHNIGVKPTDDLAIIRIIKT"
     gene            complement(1762..2283)
                     /locus_tag="BMZ54_RS26290"
                     /old_locus_tag="SAMN04488505_10958"
     CDS             complement(1762..2283)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014222316.1"
                     /locus_tag="BMZ54_RS26290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10958"
                     /product="exonuclease"
                     /protein_id="WP_089919505.1"
                     /transl_table=11
                     /translation="MAYIMVDIESDGPIPGDYSMICFGAVKVEEGLEQSFYGELAPISD
                     KFIPEALAVSGFTREQTLGFNDPLQVMSDFQQWINTVCKTDRPIFISDNNGFDWMFICW
                     YFHHFLGKNPFGFSSQNLGSLYKGMEKDTFKNFKHMRVTRHSHNPVDDARGNAEALLRM
                     KKEFGLKIKF"
     misc_feature    2284..2302
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.07"
                     /tool="antismash"
     misc_feature    complement(2285..2303)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.21"
                     /tool="antismash"
     gene            2338..2733
                     /locus_tag="BMZ54_RS26295"
                     /old_locus_tag="SAMN04488505_10959"
     CDS             2338..2733
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018614770.1"
                     /locus_tag="BMZ54_RS26295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10959"
                     /product="VOC family protein"
                     /protein_id="WP_089919126.1"
                     /transl_table=11
                     /translation="MQQHIAHLTLVVKDYDEAIAFYTRQLSFTLVEDTVLSDTKRWVRV
                     APPGSNGCCLLLAKAADEAQESRIGNQTGGRVFLFLYTDDLERDYRQMKEKGVTFVREP
                     VTEAYGKVAVFQDLYGNLWDLLEPTNK"
     gene            2787..3800
                     /locus_tag="BMZ54_RS26300"
                     /old_locus_tag="SAMN04488505_10960"
     CDS             2787..3800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014217025.1"
                     /locus_tag="BMZ54_RS26300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10960"
                     /product="arabinan endo-1,5-alpha-L-arabinosidase"
                     /protein_id="WP_238386698.1"
                     /transl_table=11
                     /translation="MPFGRTSFECLEMQWFKYIIIIIALSGNCSLLAQSPIPAHDPVMI
                     RQGSRYYLFCTGNGITVWSSADRQQWQKEPPGFNTPPAWAVAAVPKFRGHIWAPDISYH
                     NGLYYLYYVVSAFGKNTSCIGLATNKTLDPTAPDFKWTDHGKVIQSVPGRDLWNAIDPN
                     LAYDENNVPWLAFGSFWNGIKLVKLTDSLTAVAIPEQWYTLAARTRSANIPDTIAGDAA
                     IEAPFIYKKDKYYYLFVSFDYCCRGQASTYKMMVGRSEKITGPYIDKDNVPMTQGGGSL
                     VLQGNAQWYGVGHNAVCNWDGKDYIIYHGYDASDKGRSKLQVKELGWDAGGWPVVK"
     gene            complement(3826..4959)
                     /gene="hxsC"
                     /locus_tag="BMZ54_RS26305"
                     /old_locus_tag="SAMN04488505_10961"
     CDS             complement(3826..4959)
                     /codon_start=1
                     /gene="hxsC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03977.1"
                     /locus_tag="BMZ54_RS26305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10961"
                     /product="His-Xaa-Ser system radical SAM maturase HxsC"
                     /protein_id="WP_089919128.1"
                     /sec_met_domain="Fer4_12 (E-value: 2.4e-07, bitscore: 25.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.1e-14, bitscore: 48.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLKTKGKPHNIFYPVVGRVTKDHTANAEILLIEGEIPTDAITRF
                     SLVLTTLDIDKAIDKPSVYAIPGFEHLSEGDIVLVNTSGMINTLYRVNSNHNFLLFTER
                     CNSNCLMCSQPPKNRDDTSYFFDTYKQLIPLIPKNCFELGITGGEPTLLGERFFQLLEL
                     LASNLPETEIHCLTNGRTFAWPHITNRLGELSYNRLMLGIPIYSDYYQLHDYVVQAKGA
                     FDQTIQGLYNLAKNNIRVELRIVLHKQTIPRLAQLAKFIYKNLPFAEHITFMGLEYQGY
                     TPHNIDKLWIDPVDYSDILSEAINYLSDYGMNVSIYNSQLCTTPKNIWQFARKSISDWK
                     NIYLDECNKCAVLNECGGLFQSNAAKHSAYIKAIMQE"
     gene            complement(4959..6464)
                     /gene="hxsB"
                     /locus_tag="BMZ54_RS26310"
                     /old_locus_tag="SAMN04488505_10962"
     CDS             complement(4959..6464)
                     /codon_start=1
                     /gene="hxsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03978.1"
                     /locus_tag="BMZ54_RS26310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10962"
                     /product="His-Xaa-Ser system radical SAM maturase HxsB"
                     /protein_id="WP_089919130.1"
                     /sec_met_domain="PTHR43273 (E-value: 6.8e-44, bitscore:
                     144.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.3e-07, bitscore: 24.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTDSLPNENATRKFKEFEYFGSKSDFSYYLLPFRFHNINEQREI
                     LVNEIGDFLIVPTGTAELIIERKINPIAYPELYGDLIANFFISEQPIPSLIDVLATRYR
                     TKKSFLDYFTSLHIFVISLRCEHTCHYCQVSRVTSDKSRYDMSKEHIDAGIEMMMQSPN
                     PHVTMEFQGGEALLAFDNIIYAVEKAKEAAIMRKKTVSYVICTNLAPLTEEMLIYFKEN
                     NILISTSLDGPDFIHNKNRHKPHSNSYQYAVNGIIKCREELGAENVSALLTTTNLSLQY
                     PEEIVDEYVRLGFKNMFLRPISPYGFATRNEGKNKYVTQEFLEFYKKALKKIIQYNLDG
                     HFIREDYASIILKKMLTPFPVGYVDLQSPAGLINSVIVFNYDGEIYATDESRMLAEMKD
                     FTFKLGTLGINTYEEVFYGKKSLELSEAFLNESLPGCSDCAFQSYCGADPVFNYTTQGD
                     IYGHRPTSSFCQRNMEIMRHLIELMDSDKKIEKIFRTWITGKN"
     gene            complement(6458..6835)
                     /gene="hxsD"
                     /locus_tag="BMZ54_RS26315"
                     /old_locus_tag="SAMN04488505_10963"
     CDS             complement(6458..6835)
                     /codon_start=1
                     /gene="hxsD"
                     /inference="COORDINATES: protein motif:HMM:TIGR03976.1"
                     /locus_tag="BMZ54_RS26315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10963"
                     /product="His-Xaa-Ser system protein HxsD"
                     /protein_id="WP_089919132.1"
                     /transl_table=11
                     /translation="MNFHINDHQLCLLIDGRQYNEKVLYKCFYWYSNNYSVDIDIETGP
                     FYKITLQATKESDSLSWNHLIEKIKKDLIDFKLRDIISQETQTIRELIVAKAFAYYEIQ
                     ETPQTNISDPVGFNPENVLEC"
     gene            complement(6816..7562)
                     /locus_tag="BMZ54_RS26320"
                     /old_locus_tag="SAMN04488505_10964"
     CDS             complement(6816..7562)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.5"
                     /locus_tag="BMZ54_RS26320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10964"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_089919134.1"
                     /transl_table=11
                     /translation="MKEGKKLGFLNLAKKSLAVLSAALTTLSPAKAAPINESVNMDDNK
                     NLNYEEYHKNVLKPKLVLKLNMANPEKSLVLMHRSHSSHSSHSSHSSHSSHYSSSYSSS
                     ATSSYQSSYASPGGSSKASSSSSSYTPSSPSALPLSAPSKSGSSSYNASSSSQYNNQST
                     TNLNSSTYKLGERELFKGCEGKDVEELQKLLMLIKFDVVLTGYFGNQTEAIVIKFQMAN
                     NLDANGRVDAKTLNAIKRKQHELSHK"
     misc_feature    7821..7834
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.07"
                     /tool="antismash"
     gene            7891..8532
                     /locus_tag="BMZ54_RS26325"
                     /old_locus_tag="SAMN04488505_10965"
     CDS             7891..8532
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BMZ54_RS26325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488505_10965"
                     /product="hypothetical protein"
                     /protein_id="WP_089919136.1"
                     /transl_table=11
                     /translation="MQLIPGLKEQWLNLTAQYTTDEPLLLQEFDHLTTHYSTINRFYHN
                     LQHIHNLLLLQQQYAEDIKDHDTIGFAIFYHDLVYDVMKTDNEEESALAAGRFLQQTNV
                     PVTQAEKIMNYIRATKSHDGNSPDNDLLLFLDFDMAILGSAPEEYQQYAQQIRMEYNSY
                     NDTAYNMGRTKVLQHFLQMPHIYSTETFRNKYEQQARENINAELAALKTT"
     gene            complement(8525..9793)
                     /locus_tag="BMZ54_RS26330"
                     /old_locus_tag="SAMN04488505_10966"
     CDS             complement(8525..9793)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012792664.1"
                     /locus_tag="BMZ54_RS26330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10966"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_089919138.1"
                     /transl_table=11
                     /translation="MKMIPSVILWGLLPCAVMAQKQQDGLPAPYATKSVKNFSKVVGWE
                     HGQQPVAPKGFTVSLYADGMDNPRWAYVTPNGDVLVAEANTIKNAFMQAGAVILGAAKA
                     ENLKKSANRISILRDTTGDGHPDIKEVFLEGLNQPFGMLIMNGYLYVANTDALLRFPYQ
                     PGQMKMESEGEKLLDLPAEKRNQHWTRNIITNADSSKIYIAVGSVDNLGDNGKEVNPRR
                     ACILEVDPDGKNERVYASGLRNPVGMAWAPGTKTLWAAVNERDELGDNLVPDYLTSVKD
                     GGFYGWPYSYFGQHPDPRIEAPRPDLVKKAIVPDVPLGSHTASLGLAFYTKKAFPAKYQ
                     GGAFVAQHGSWNRSELAGYKVVFVPFKNGKPTGKPQDFLTGFETDKEGEVHGRPVGVTV
                     LPDGSMLVTDDVNDKIWQITAAK"
     misc_feature    complement(9821..9834)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.15"
                     /tool="antismash"
     gene            10001..11110
                     /locus_tag="BMZ54_RS26335"
                     /old_locus_tag="SAMN04488505_10967"
     CDS             10001..11110
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="BMZ54_RS26335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10967"
                     /product="terpene synthase family protein"
                     /protein_id="WP_089919140.1"
                     /sec_met_domain="T1TS (E-value: 1.9e-24, bitscore: 80.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTHNRQQTSAAVLARVQQSYSNLTGAAPRFSLLELFNFEGFNLN
                     DYCQTFSPHPQIKPLLQEARAFGEQYGIWLDNAAHYISCATFLYPNAGLERMRAIVQNL
                     AIDYYLNDTMGRDIFVHLSPAEQEAATQMKKRMYSLREDLYMDEPNATLIEQANVEVLT
                     YIRDTSSMSWFKEFLRLYSWHIYVAHKDCNMNAAGKLASVDEYIDSRCHLSGMHHVVKF
                     IEYSEGLFLDWDWLAERGIHKQLERLHDITAAIGGLMNDLFSFEKEVIRNGADSNLVMV
                     ILCNQPALTLEEGIRQAAGIVRNQLIEFLALMDYVKTAVQQEPLMLSHLQGLERCVQAS
                     WIWQVYTRRYKSADSIFVETRLPGVAAPQ"
     gene            complement(11111..12835)
                     /locus_tag="BMZ54_RS26340"
                     /old_locus_tag="SAMN04488505_10968"
     CDS             complement(11111..12835)
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="BMZ54_RS26340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10968"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_089919143.1"
                     /transl_table=11
                     /translation="MKAHQIWRSIRKTGTKGVADEELAQRIMMVNTLSFSLCCLSFLVG
                     SVYFILSGKLSILIPASIECVLAATAVVLNNYRHYHAAALVTFFVQCMAAIYFGLLLGN
                     VIELQAMVIFLFLITFLLFKKTSTRVICLISAVVILMIIEGNYYFHFVNQVPLDLQLTV
                     IFKALSIAGVLLVILVVGRPYVLSKDRLHKTNHFKKIFIYQITHELRTQLNAVYYIAQL
                     IKREIRLDPHLKKINPYIDLLFTVVGNTRNIINNVLDMSKIEAGKMEDVQEESFEIDAF
                     FERLMAVHKVTAKTRNMQIQLQIDPKMPPVIICDSFKLSQAIANLLSNAVKYADRNSTI
                     FLKLHKNNAQTWSIQVVNKGPGIEADKLSAIFELFVTNSPNRYTESTGLGLFIARNMVH
                     ALKGEIHAESQPQGNTTFTIQLPLQPGEVADVHETQEEDIDLSHVHIMVADDNEMNNIL
                     FSKYLSMCGCTITSVNNGVEVLQKLEQGHHLPDVILLDHKMPEMDGETTLYHLKKDPRL
                     QNIPVIVCTGSFEFQELLMQAGACDIVIKPIDQPSLFKVISQHLPHFNEISAGSHPV"
     misc_feature    13232..13245
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     misc_feature    13274..13291
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.41"
                     /tool="antismash"
     gene            13685..14338
                     /locus_tag="BMZ54_RS26345"
                     /old_locus_tag="SAMN04488505_10969"
     CDS             13685..14338
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008583484.1"
                     /locus_tag="BMZ54_RS26345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10969"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_089919145.1"
                     /transl_table=11
                     /translation="MKVALIGATGFVGSHLLPELLERGHQVTAIVRNPDKLTLEHPNLV
                     VKKGDVTNEAEVAALVSGLDAVISSFNAGWTNPNLYNDFLSGSKAIQSGVKKSGVKRFI
                     TIGGAGSLEIAPGKQLVDTPEFPKEYLPGATAARDYLNIIKEEKELEWTFISPAIEMSP
                     AGAHGRTGAYRTALNNPVFDAEHRSRLSVEDLAVVIADELENPQHIRQRFTAAY"
     gene            14465..15337
                     /locus_tag="BMZ54_RS26350"
                     /old_locus_tag="SAMN04488505_10970"
     CDS             14465..15337
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013429.5"
                     /locus_tag="BMZ54_RS26350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10970"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_089919147.1"
                     /transl_table=11
                     /translation="MILRKPALFSCLLLTVLTSYQPANAQKGQRLLKNHPGVVSYTYRK
                     DFAKDMPGTLDMVKKNGFTDIEFSNLFGQTAQDIRKWIDERGIKCSSFGVSYEDLTTKT
                     DQVAKNAKTLGAKFVRVAGFPHSKTGLTLDEAKQGISEFNRVGKILKDQYGLTLIYHNH
                     GFEFQPYEKGTLFDYIVQQTNPRYVSLEMDILWVFFPGQDPVALLKKYGNRFKAMHVKD
                     LKKGVEGNLSGGTNPENDVALGTGQINIPAVLKAAKRSAIEHYYIEDESSNVETQVPQS
                     VQYLLGLKE"
     gene            complement(15310..16587)
                     /locus_tag="BMZ54_RS26355"
                     /old_locus_tag="SAMN04488505_10971"
     CDS             complement(15310..16587)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024829.5"
                     /locus_tag="BMZ54_RS26355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10971"
                     /product="HlyD family secretion protein"
                     /protein_id="WP_089919149.1"
                     /transl_table=11
                     /translation="MPQYQHHHEEVQDIMSKMPHWIVRRGITLLFAVVMLLFAGAYFIH
                     YPDVITTQVNITSANPPVKIVAQTSGKISELFVQNNAAVRENAPIYILENAARYNDIRL
                     LQTLLNQLDTSFNLAPTLRRFNFAQPLQLGALQGGYAALYQAVNQYLFFTDKHFTTQKV
                     AQLQSQLTTQHQLNEELQRKDVMLQQQLMLEQKRFKIDSQLAREKVIAPLELDNSKRQL
                     LDKQMTADATRANLLQNKLQQTEYLKTITDLQQQSLQQENDLQQKVREQVKQLQGQLEV
                     WEQQYLVKSPVAGKVSFFKFWKAHQFVSSGEAVLMIVPPVQHYVAKATLPVFGAGKVKK
                     GQKVLIKLSAYPFREFGMIRGNISNVSAVALDTAYAMDIQLANGLLTTAQRQIPSQPQL
                     PGIAEVLTNDMSILERLFYSLRPSRY"
     gene            complement(16598..18805)
                     /locus_tag="BMZ54_RS26360"
                     /old_locus_tag="SAMN04488505_10972"
     CDS             complement(16598..18805)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364871.1"
                     /locus_tag="BMZ54_RS26360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10972"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_089919151.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.6e-35, bitscore:
                     113.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFPIYKQLDTMDCGPTCLRMIAKHYGRHYSLDSLRQMSDMSREG
                     VSLLGISEAAEKIGFRTLAAAVNFEQLDKEVALPCILHWNQDHYVVLPPQNYNSNKASD
                     KLLIADPGHGLVKIDKAAFLKSWASKEDAQGIVLMLEPTPLFYQHEEDAAARKGFQFLF
                     QYLTPYRKYITQLVLGMLLGSLLALVLPFLTQSLVDYGVNYQNMGFIQLVLVSQLVLFI
                     GTTAVEMIRSWILLHMNSRINMSIISDFLTKLMQLPIRFFDAKMIGDITQRINDHGRIE
                     QFLTTQTLHTLFSFVSLLVFSVVLGIYSLKILFIFLVGSVLSVVWIVFFLQKRKELDYK
                     RFQQMSNNQNSLYELITGMQEIKLNNCETPKRWEWERIQARLFRLNISSLTLEQYQQTG
                     NLFFSQLKNILISYIAAREVVSGQMTLGMLLGVSYMIGQMNSPLEQLLAFFRSAQDARI
                     SLERLGEIHNRDNEEPATVTDTFTLQTPLLQNGDLQLDNLSFQYSSGSSPYVLKDVNLN
                     IPEGKVTAIVGSSGSGKTTLLKMLLRFYEPVAGKLLVGHTELSGLSPKWWRRQCGVVMQ
                     EGFIFSDTIARNIAVGDEKINERRLLHAARVANIENFIQQLPAGFATKIGNIGNGLSTG
                     QKQRLLIARAVYKDPQYLFFDEATSALDANNEKIIIENLQQFFQGKTVVVIAHRLSTVK
                     HADQIVVLEQGRIVEVGNHQTLTRKRGKYFELVKNQLELGD"
     gene            19032..19205
                     /locus_tag="BMZ54_RS33005"
                     /old_locus_tag="SAMN04488505_10973"
     CDS             19032..19205
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038153.1"
                     /locus_tag="BMZ54_RS33005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10973"
                     /product="class I lanthipeptide"
                     /protein_id="WP_156093028.1"
                     /transl_table=11
                     /translation="MKKQSQKKLTLGKITVASLTKADQQMVKGGLPIDFTKRSVCADAC
                     CASDINAQCRTL"
     gene            19281..20474
                     /locus_tag="BMZ54_RS26365"
                     /old_locus_tag="SAMN04488505_10974"
     CDS             19281..20474
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="BMZ54_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_10974"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_089919152.1"
                     /sec_met_domain="LANC_like (E-value: 1.5e-50, bitscore:
                     165.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLYKILADISTALDHFIEQETDPGLLSGYGGCALFYAYYHRLT
                     GKEEYLHKMELVVMKALHAMATEEMIHSHCSGVAGISWCLQHLMQQGFIEKEEGANAFE
                     ETDALLYRYMDQELSEMRYDLLHEGLGPALYFLEREAEPAINVYLENVVTRLEKAAVPM
                     ATGISWKDGFVKKDQEGDHYNLGLAHGMPAILAVLGMIYERGIAQERARSLLEKGIQWL
                     LTTRNQNISTGMSCYPTMVTAGNKPVGNPQSRLGWCYGDPGIAITLWNAGVRLQNESFK
                     QEACDILLQTMQHRDAENGSVRDAGLCHGSMGLAHIYNRMYAGSGNELLRRGMDHWLQQ
                     TLAFRTWADGPAGFKCHTMSGKVNSYNLLEGITGIGLALMAIADPQAAAWDRCMLLS"
     misc_feature    20655..20669
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.17"
                     /tool="antismash"
     misc_feature    complement(20711..20726)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.98"
                     /tool="antismash"
     misc_feature    20837..20851
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
ORIGIN
        1 gaatgaaagc ataaccatac atatcaccaa cctgggctgc acgttaatgt ccatttatac
       61 gcctgaccgg aatggtgtaa tgaagaacat tgtggctggc tttgaacagc ctgcggatta
      121 tgcaaataat ccctggtatt ttggctgcgt ggtaggccgt tatgccaacc gtattgccgg
      181 tggccgtttt ttgctggacg ggcaacctat tcagcttact gtaaataacg ataccaacca
      241 cctgcacgga ggctttaatg ggtttcacac taaggtgtgg acgctggatt ccctgatccg
      301 cgaaggggag caagccggcg tagtactgga atataccagc aaagacgggg aagaaggtta
      361 cccgggcaac ctgcaggcca aagtacaata tgtgttgaac cagcagaacc agctggtgat
      421 cacgtatact gcggttacgg ataaacgaac gcctgtaaat tttaccaacc atagttattt
      481 taacctgagc ggttttgaac agccactgat cacagatcat gtgctgcagg tgaatgctgc
      541 tcattacaca gagaagaatg cgcaaaatgt acctaccggc cgtatattgc cgctggccgg
      601 cactggagcg gatttttccg tacctacgcg catcggcaag cgtattaatg attttctgca
      661 ggataagggt tttgatcata actatgtatt gaaccagggt cccggacctg tggcgatatt
      721 agaggatccg catacaggca ggtatttgaa ggtattcacg gaccaaccgg gtatgcaggt
      781 gtatacggcc aattattggg atggaagtat tgttgggcag cagggtaagg tgtatgtaca
      841 gcatggtgcg gtggcactgg aaacgcaggc atttccggat agcccgaatc atgcggagtt
      901 cccggatacg gtgctggagc cgggggaggt gtatgaaaca acaacagttt atgagtttgg
      961 ggtgaagggg taaagtgcga tgagtggcgg tttattggaa aataaaagaa atttgtactt
     1021 ttacattccg catgaatgtc tactcagtgc tccaaatagg agaataccat ttaaacaatt
     1081 gtgaagatta ccttttttat gagccaattg gcacggacaa attattgtgt gccgttatgg
     1141 acggctgtac gatggggaag gatagttatt tcatagctac ccttatcggg aaattgctac
     1201 ggaaaatagt aaaggcaaaa aactatgaag aattttacca gttgccattt cttgagttgt
     1261 cgttggaaga acagttgaaa gtaatactaa aggaactctt tgagtcactt aaaaatatta
     1321 aaaatgagct gctgttagag aagaatgaaa tgttgtcaac actcacaatc ttaatagcaa
     1381 accttaagga cgaacaggga gtgatacttg taattggaga tggggtaata tgtattaatg
     1441 gagcaataac agaatttgat caggataata aacccgatta cgttggatac cacttatcag
     1501 aaaattttga ggaatggtat gataagcagc aacaaaaaat taagttcagc ggaataaaag
     1561 atatcagcgt ggctacagac ggaataatgt cctttaaaag tatagaacaa aaggcaaatt
     1621 taggtgatat agatccagta caatatatgc ttaatgatac cagcaaaata gagcatgagg
     1681 aaatgttgaa tatgaagttg aagtttctgg aacataatat cggggttaaa cctacagacg
     1741 acctggctat aatcagaata attaaaactt aatcttcaat ccaaactcct tcttcatcct
     1801 taacaaggct tcagcatttc ctcttgcatc atccacggga ttgtgtgaat gtctggtaac
     1861 ccgcatgtgt ttaaagttct tgaaagtatc tttttccatg cctttataca aactgccgag
     1921 gttctgagag ctgaatccaa aaggattttt ccccaggaaa tgatgaaagt accagcagat
     1981 aaacatccag tcaaaaccat tgttgtcgct gataaaaatg ggccggtcgg ttttacagac
     2041 ggtattgatc cattgttgaa aatcactcat tacctgcaga ggatcattaa atcccagggt
     2101 ttgctcgcgc gtaaacccgg atacggccag cgcctccggt ataaatttgt cggatatagg
     2161 cgccagctcg ccataaaagg actgttctaa accttcctcc acctttacgg cgccaaaaca
     2221 gatcatagaa taatcacctg gaataggacc atcgctctca atatcaacca ttatatatgc
     2281 cattgctata tttttaaaca gtgcaaaatt gcgaaaaaga cggttaactt tatcatcatg
     2341 caacaacata tcgcccattt aaccctggta gtaaaagatt atgatgaagc catagccttt
     2401 tatacccgtc aattgagctt cactttagta gaagatactg ttctaagcga taccaaacgc
     2461 tgggtgcggg tagcgccacc cggatcaaac ggctgctgtt tactgctggc caaggcggcc
     2521 gatgaagctc aggaaagccg tatcggcaac caaaccggcg gacgggtatt cctgttcctg
     2581 tacacggatg acctggaacg ggattaccgg cagatgaagg aaaaaggtgt cacttttgta
     2641 cgggagccgg taactgaagc ctatggaaag gtggccgttt tccaggactt gtacggtaat
     2701 ttgtgggacc tgctggagcc tacgaataag taaacagtgt ggacgcatac ttgagaaatg
     2761 ctttgcatgt aggaacataa ctggaaatgc cttttggccg aacctcattc gaatgcctgg
     2821 aaatgcaatg gtttaaatac atcatcataa taatagccct gtcaggaaat tgttccctcc
     2881 tggcacaatc ccccattccc gctcatgacc cggttatgat ccggcagggg agccggtact
     2941 acttattctg tactggcaat ggtatcacgg tatggtcatc agcagaccgg cagcaatggc
     3001 aaaaagagcc gcctggtttt aacacacctc ctgcatgggc cgtggccgca gtaccgaaat
     3061 tccgcgggca tatctgggcg ccggatatca gctatcataa cggattatat tatttgtatt
     3121 acgtcgtatc tgcattcggt aaaaatactt cctgcatagg cctggctact aataaaacat
     3181 tagacccaac tgccccggat tttaaatgga cagatcacgg aaaggtgatc caatccgttc
     3241 ccggccgcga tctatggaat gccattgatc ccaacctggc atatgatgaa aacaatgttc
     3301 cctggctggc cttcggctct ttttggaatg gtattaagct ggtgaagcta acagacagcc
     3361 taacggcagt ggctattccg gaacaatggt atacccttgc ggcccgcacc cgcagcgcaa
     3421 atattccgga taccatagca ggcgatgcgg ctatagaagc gccttttatc tacaaaaaag
     3481 ataaatatta ttacctcttt gtttcctttg attattgttg tcgcggccag gccagtacgt
     3541 ataagatgat ggtagggcgt agtgaaaaaa taaccggccc ttatattgat aaagacaatg
     3601 tacctatgac gcaaggcggc ggtagcttag tattacaagg caatgcgcaa tggtatggag
     3661 tggggcacaa tgcggtgtgt aactgggatg ggaaggatta tatcatctat catggttatg
     3721 atgcgagtga caaaggccgg tcaaaactgc aggtaaaaga attgggttgg gatgcaggag
     3781 gatggccggt agtgaagtga tggacggaat tgattagaca atctattatt cctgcataat
     3841 agcttttata taagcactat gtttagcagc atttgactgg aataagcctc cacattcatt
     3901 caatacagcg catttattgc actcatccaa atatatattt ttccaatcag aaatcgactt
     3961 ccttgcaaat tgccatatgt ttttaggcgt ggtacaaagt tgagaattat aaatggatac
     4021 attcattccg taatccgaca aataatttat ggcctcggaa agtatatctg aataatcaac
     4081 aggatcaatc caaagtttat caatattatg gggggtataa ccctggtatt caagtcccat
     4141 aaaggtaata tgttcagcaa acggaaggtt tttataaata aattttgcca attgggcgag
     4201 tcgcggaatg gtctgtttgt gtagtacaat tctcaattca accctgatat tatttttggc
     4261 taagttatat aatccctgaa tcgtctggtc aaaagcgcct ttggcctgaa caacataatc
     4321 atgtaactgg taatagtcgg aataaatagg tatacccagc attaacctat tgtatgaaag
     4381 ctcacccagt ctattcgtaa tatgcggcca tgcaaaagtt cttccattag tgaggcagtg
     4441 aatttcagtt tccggtaaat tggaggccag tagttccaat aattgaaaaa aacgttcacc
     4501 gagcaatgtt ggttcacctc cggtaatacc taattcaaag caatttttcg ggatgagagg
     4561 tataagctgt ttgtaagtat cgaaaaagta agaggtgtca tctctgtttt tgggaggctg
     4621 tgagcacatc aaacaattgc tattgcacct ttctgtaaat aaaagaaaat tatgatttga
     4681 atttacacga tataaggtat taatcatgcc actcgtattt accagcacaa tatccccttc
     4741 agaaaggtgt tcaaaaccag gaattgcata aacggatggt ttgtctattg ccttatcaat
     4801 gtcaagtgtg gtaagtacta aagaaaatct ggttatagca tcagttggga tctcaccttc
     4861 tataaggagt atttctgcat ttgcggtatg gtctttggtt accctgccaa caacaggata
     4921 gaaaatattg tgaggttttc ctttggtttt taattgcatt agtttttgcc agttatccag
     4981 gttctgaata ttttttctat ttttttatca ctatccatta gctcaataag atgcctcata
     5041 atctccatgt ttctttggca gaaagagcta gttggcctat gaccataaat atcgccctga
     5101 gtagtataat tgaatacagg atccgctcca caataggatt gaaaggcgca gtcagagcag
     5161 ccaggtaagg attcatttaa gaaagcctct gataattcga gtgatttttt gccatagaaa
     5221 acttcctcat aagtatttat acctaatgtt ccaagtttaa acgtgaaatc tttcatttca
     5281 gcaagcattc ttgattcatc ggtagcatat atttcaccgt catagttaaa aacaattaca
     5341 ctatttatta aaccagcagg agattgcaaa tcaacataac caactgggaa gggcgttagc
     5401 atctttttaa gtataatgct tgcataatct tcacgtataa aatgcccgtc aaggttatat
     5461 tgaataattt ttttaagcgc ctttttatag aattctaaaa attcctgagt tacatattta
     5521 ttttttcctt cgttgcgggt tgcaaaacca taaggactaa taggccttag gaacatgttt
     5581 ttaaaaccca acctaacata ttcatctact atttcttcgg ggtattgaag tgataaattt
     5641 gtggttgtta gtagggcaga aacattttca gctcccagtt cttcccggca ctttataatg
     5701 ccattaactg catattgata gctattgcta tgtggtttgt gcctgttttt attatggata
     5761 aaatctggtc catccaggga agtcgatatt aaaatgttat tctccttgaa ataaatgagc
     5821 atttcctcag ttaacggggc aaggttggta caaattacat aggaaaccgt tttctttctc
     5881 attatagccg cttctttggc tttttctact gcatatatga tgttgtcaaa ggctaataat
     5941 gcctctcctc cctgaaattc cattgttaca tgagggttag gggactgcat catcatttct
     6001 atgcctgcat caatatgctc cttgctcata tcataccggc ttttgtctga agtaaccctg
     6061 gatacctggc aataatgaca ggtatgctca cagcgaagac tgattacgaa tatgtgcagt
     6121 gaagtaaaat aatcgagaaa cgatttttta gtgcggtaac gtgtggctaa tacgtcaatt
     6181 aaagagggaa tgggctgttc cgaaataaaa aagtttgcta taagatcccc atacaattcg
     6241 ggataggcta ttggatttat ttttctttcg ataattagct cagctgtccc tgttggcaca
     6301 attaaaaaat ctcctatctc gtttaccaaa atctctcttt gttcattgat attgtgaaat
     6361 ctaaacggca ggagatagta tgagaaatca gattttgagc caaaatattc gaattcttta
     6421 aattttcttg tggcgttttc attaggaagg ctgtctgtta gcattctaat acattttccg
     6481 ggttaaatcc aaccgggtct gaaatatttg tttgtggtgt ttcctgtatc tcgtaataag
     6541 caaatgcttt tgctacaatg agctctctta tcgtttgtgt ttcctggctt ataatgtctc
     6601 gcagtttaaa atcaataagg tcctttttta ttttttcgat gaggtggttc catgagagtg
     6661 aatcgctctc tttagttgcc tgaagtgtta tcttataaaa agggccggtt tcaatgtcga
     6721 tgtcgacaga atagttattg ctataccaat aaaagcattt gtacagcact ttttcattat
     6781 actgcctccc atcaattaat aaacataatt gatgatcatt tatgtgaaag ttcatgttgt
     6841 tttcttttga tagcgttcag tgttttagca tcaacccggc catttgcatc taaattgttt
     6901 gccatctgga atttgattac aatagcttct gtttggttgc caaagtaacc ggttaacacc
     6961 acatcaaact taataagcat cagcagcttt tgcagttctt caacgtcttt tccttcacaa
     7021 cctttgaata attcacgctc tccaagtttg taggtagagg agtttagatt ggttgttgat
     7081 tggttattat attgtgatga actgcttgca ttataggatg agcttcccga ttttgaggga
     7141 gcagacaagg gcaaggctga tggacttgat ggtgtataac tagagctact tgatgatgct
     7201 ttgcttgacc cacctggaga tgcgtaactg gattgataag agctggtagc gctggagctg
     7261 taagaagatg agtaatgtga actatgagaa gagtgtgaac tgtgagaact atgtgaacta
     7321 tgcgaacgat gcatgagaac caaacttttt tcaggattgg ccatattaag ctttaataca
     7381 agtttaggct taaggacatt tttatgatac tcttcataat ttaaattctt attatcatcc
     7441 atattaacgc tttcattgat aggggcggct ttagctggtg atagagtagt taatgcggca
     7501 gataagactg ctaggctttt ttttgctaaa tttaagaagc ctaatttttt tccttctttc
     7561 atttccgtgg tttaaggttg attggatatg attggtagaa ttcggttata ctaaggcttc
     7621 aattagggaa tgattaaaat ttggggctca ttatgagtat atgaggatac ctattggtta
     7681 tatttgaata ggatgaaatt agaaataaat tatgaaagag gatataacat attcatgtta
     7741 tatttaattg aggtaaatgt tgtcaaatgc tttcaacttc cctaatatcc cctacaacca
     7801 ccaagatcag gctaaaaaac ggcaggcaat ttgccaacat taccgttaaa gataaaatac
     7861 taaatttaac gcctgataaa ctaatccatt atgcagctta ttcccggttt aaaagaacaa
     7921 tggctcaact taacagcgca atacactaca gatgaaccct tgctgttaca ggaatttgat
     7981 cacctcacta cacattattc aaccataaac cgtttctacc ataatctgca gcatattcat
     8041 aacctgctgt tattacagca gcaatatgcg gaagacataa aagatcatga taccatcggc
     8101 tttgccatct tttaccacga cctggtgtat gatgtaatga aaaccgataa tgaagaagaa
     8161 agcgcgctgg cagccggccg tttcctgcaa cagaccaatg tgccggtaac acaggcggag
     8221 aagatcatga actatatacg tgccaccaaa tcgcacgacg gtaatagccc tgataacgac
     8281 ctcttattat tcctggattt tgacatggcc atcctgggca gcgctccgga ggaatatcag
     8341 cagtatgcgc agcagatccg catggagtat aattcgtaca atgataccgc ctataatatg
     8401 ggccgcacca aggtattgca gcactttctg caaatgcccc acatttatag tacagaaacc
     8461 tttagaaaca aatatgagca gcaagcccgc gaaaatatta acgcggaact ggctgcacta
     8521 aaaactactt agcagcggtt atctgccata tcttatcatt cacatcatcc gtcaccagca
     8581 tagagccatc cggtaatacc gtaacaccta cgggccggcc atgtacttcg ccttctttat
     8641 ctgtttcaaa ccccgtcagg aaatcctgtg gtttgccggt gggtttgcca tttttaaaag
     8701 gaacaaatac cactttatag ccggccagtt cagaacggtt ccaggatcca tgctgggcca
     8761 caaaggcgcc gccttgatat tttgcgggaa atgctttttt agtgtaaaag gccagtccca
     8821 gggaggcagt atgtgagcct aatggtacat ccggtacaat ggctttttta acgaggtcag
     8881 ggcggggggc ttcaatacgc ggatcaggat gctgtccgaa gtaggagtaa ggccagccgt
     8941 aaaaaccgcc gtcctttaca ctggtcaggt aatccggtac caggttgtcg cccagctcat
     9001 cgcgctcatt cactgctgcc cataatgttt tggtgccagg cgcccaggcc attcctaccg
     9061 ggttacgcag gccggaagca tatacacgct cgttcttgcc atccgggtct acttccagta
     9121 tgcaggccct gcgcgggttc acctctttac cattatcccc caggttgtca acagagccta
     9181 cggcaatata gatcttagag ctgtctgcat tagtgataat attacgtgtc cagtgctggt
     9241 tacgtttttc agcgggcagg tccagcagtt tttcgccttc ggattccatt ttcatttgtc
     9301 ccggttgata ggggaaacgt agcaatgcat ctgtattggc tacatacagg tagccattca
     9361 taataagcat tccaaaaggc tggtttagcc cttccaggaa cacttcttta atatccgggt
     9421 gcccatcgcc tgtagtatcc cgtaaaatgg agatacggtt ggcgctcttt ttcaaattct
     9481 cagccttggc agcgcccagt attacggcgc cggcctgcat aaaagcgttc ttaatggtat
     9541 tggcctctgc taccagcaca tcgccatttg gcgttacata ggcccagcgt gggttgtcca
     9601 tgccgtctgc atacaggctt acggtaaatc ctttgggtgc aaccggttgc tgtccatgtt
     9661 cccaaccgac caccttgctg aagtttttta ccgatttggt ggcatatggc gccggcaaac
     9721 cgtcctgctg cttttgcgcc ataacggcgc atggtaacaa gccccaaagt ataacggaag
     9781 gtatcatttt cataacagta ctatttacat gataagcagc gcaaaaggca tgcccgccac
     9841 agtttgggca atcacaaaaa gaaggatacc cgtcattaaa ttgcgtaact tattcatgat
     9901 ttaactccag gatgcatccc agtttattca gagcatagcc atttatttag agcgtagcca
     9961 ttagagataa ccatttacaa taaccataaa tcaatcagtc atgtttacac acaatcgtca
    10021 acagaccagc gctgctgtat tggcgcgcgt acaacaatcg tacagcaatt taacgggagc
    10081 tgctcccagg ttctcgctgc tggagctgtt caactttgag gggtttaact taaacgatta
    10141 ttgccagaca ttcagcccgc atccgcagat caagcccttg ctgcaggagg cgcgggcatt
    10201 tggggagcag tacggcatct ggctggataa tgccgcacat tacattagct gcgccacttt
    10261 cctgtatccc aatgcaggcc tggagcgcat gcgggccatt gtacaaaatc tggccattga
    10321 ttattacctg aacgacacta tggggcgaga tatttttgtc cacctgagcc ccgccgaaca
    10381 ggaagctgcc acgcaaatga aaaaaagaat gtacagtctg cgggaagacc tgtatatgga
    10441 tgaacccaat gctacattga ttgaacaggc caatgtggaa gtgttaacct atatccgcga
    10501 tacctcgtcc atgtcctggt ttaaagagtt cttgcgcctg tattcctggc acatttatgt
    10561 agcgcataag gattgtaaca tgaatgctgc aggcaagctg gccagcgtgg atgagtacat
    10621 tgacagccgc tgccatttgt ccggcatgca tcacgtagta aagtttattg aatacagtga
    10681 agggctgttc ctggactggg actggcttgc ggaaaggggc attcataaac aactggaacg
    10741 gctgcacgat attactgcag ctattggcgg gttaatgaac gacctgttct cttttgaaaa
    10801 agaagtgatc cgtaacgggg cagattccaa cctggtaatg gtgatcttat gtaaccagcc
    10861 tgcgcttacc ctggaagagg gcatccggca ggcagccggt attgtgcgta accagctgat
    10921 agaattcctg gcattaatgg attatgttaa aacagccgta cagcaggagc ctctaatgtt
    10981 atcgcacctg cagggtttgg agcgctgcgt acaggcgtcc tggatatggc aggtatatac
    11041 ccggcgttat aaatcagcag attctatttt tgtggaaacc cgcctccctg gcgtggctgc
    11101 gccgcaatag ctacacaggg tgagagccgg cgcttatctc gttaaaatgg ggtaagtgct
    11161 ggctgatcac cttgaataaa gaaggctgat cgatgggttt gataacaata tcgcaggcgc
    11221 cggcctgcat cagcagctcc tggaattcaa agctgcctgt acatacgatc acgggaatat
    11281 tttgcagccg cggatctttt ttcaggtgat acagggtggt ttctccatcc atttccggca
    11341 tcttatgatc cagcaatatc acatccggca ggtggtgtcc ctgctccagc ttttgcagca
    11401 cttccacacc attatttacg ctggtaatag tacagccgca catgctcagg tatttggaaa
    11461 aaaggatgtt gttcatttcg ttgtcatccg ctaccataat atgtacatgg ctcaggtcaa
    11521 tatcttcctc ctgggtttca tgcacatcag ctacctcacc gggttgtagg ggaagctgta
    11581 tggtaaaggt ggtatttccc tggggctggc tttctgcatg gatctcgccc ttcagcgcat
    11641 gcaccatgtt cctggcaata aacagtccca ggccggtgct ttccgtatac cggttaggac
    11701 tattggttac aaacagctca aaaatggcgc tgagcttatc ggcctcaatg cccggccctt
    11761 tgttcaccac ctgtatactc caggtttgtg cgttgttttt gtgaagcttt aaaaatatgg
    11821 tgctgttccg gtccgcatat ttcacggcat tgcttaacag gttggcaata gcctggctca
    11881 gcttaaagct gtcgcatata attacgggcg gcattttagg atctatctgc agctggatct
    11941 gcatattccg ggttttggcg gtaaccttat gtacggccat cagcctttca aagaaggcat
    12001 ctatttcaaa agattcttcc tgcacatcct ccattttacc cgcttctatc tttgacatgt
    12061 ccagcacatt gttgataata ttgcgggtgt tgcctactac ggtgaacagg aggtcaatgt
    12121 agggattgat ctttttcagg tgaggatcca gccttatttc gcgtttgatc agctgggcta
    12181 tataatacac cgcattcagc tgggtcctta attcatgtgt aatctggtaa atgaagatct
    12241 ttttgaaatg attggtcttg tgcagccggt ccttgctaag cacatagggc ctgcctacta
    12301 ccaaaatcac cagtaatacg cctgctatgg acaatgcttt gaaaataaca gtaagctgaa
    12361 gatccagcgg aacctggtta acgaaatgga aataatagtt cccttcaatg atcatcagga
    12421 tcaccacggc agagatcaga cagatcacac gggtactggt ctttttgaaa agcagaaagg
    12481 tgatcaggaa taaaaagatc accatggcct gcagctcaat tacattgcct aaaagcaatc
    12541 caaaataaat ggcggccatg cattgaacaa aaaaggtaac cagcgctgct gcatgatagt
    12601 gccggtaatt attcagcaca acggccgtag cagccagtac acattcaatg cttgccggga
    12661 taaggataga tagtttcccg gataatataa aataaacgct gcccaccagg aaactcaggc
    12721 agcagagtga aaagctgagg gtgttcacca tcatgatccg ttgcgcaagc tcctcatcag
    12781 ccactccttt ggtgccggtt ttgcgaatgg aacgccatat ttgatgcgct ttcataacag
    12841 tttgtttgta ggtaattttc agggaaacac tttatattaa acttgctgaa acggcataga
    12901 ttgtccctta ctacctttcc ggtacctttt aatgttgtaa tattaaatag cagttgcagc
    12961 ccctaatatc tgataggcta atgatcgacg tacgatatta aataccgggg tgctgttaaa
    13021 attgtattat cccaactcaa tttacagaat ttataattat aaaagccact ggctgcatgc
    13081 tcccttaaaa caattccccg gccttgaaag accggggagg cttgataatg tcattaaaat
    13141 atgataacaa aacgagtatt gtagccttaa cctcgaaatg ttatgtacct atatacgaga
    13201 taaaataagt ttaggactta accggcccgg aattttttaa tgaaatttta tcttcccaca
    13261 cagttgttga gtgatgtaaa gtatttgtaa acaattgttt atgactcatc attaataccc
    13321 cttacgaaca ggttatttta tgttaatttt ttttgtggag caaaccgtgg tatataaagg
    13381 tcaaccattc cttcttcctg aacattacct gcttacataa aggttacctg cttccggcaa
    13441 ccaggtgcag aatgtaaaaa gcccacttac gtgttatata cctggcaggc cgcaattgcc
    13501 ccgtgagcgg tcatttccga taggattttc actttggaac tttcccggcc aatggcttgt
    13561 tatctgttat agcttttccg gattgcccgg aagctccggc aaataatttg gtatttatac
    13621 aaatatgcct acctttgaac tgtataattt aaaattacag tttaagcact aaacattatt
    13681 tacaatgaaa gtagctctca taggcgcaac cggtttcgta ggatctcacc tgttacctga
    13741 attactggaa cgtggtcacc aggtaaccgc tattgtaaga aatcctgata aattaacgtt
    13801 agagcatccc aacctggtag taaaaaaagg cgatgtaacg aatgaagcag aagtagccgc
    13861 gctggtaagc ggcctggatg ccgtgatcag ctcatttaat gccggctgga ccaatcccaa
    13921 cctgtataat gatttcctga gcggttccaa agccattcaa agcggagtga aaaaatcggg
    13981 cgtaaaacgt tttattacca taggcggcgc cggtagcctg gaaatagcgc ctggcaaaca
    14041 gctggtagat acccctgaat ttccgaaaga atacctgccc ggcgctactg cagcccggga
    14101 ctatctcaat atcattaaag aggaaaaaga gctggaatgg acgttcatta gcccggctat
    14161 tgaaatgagc cctgccggcg cccacggccg cacaggtgct taccgtactg ccctgaataa
    14221 cccggtattt gatgcagaac accgcagccg tttgtctgta gaagacctgg ccgtggtaat
    14281 tgcagatgag ctggaaaacc cgcaacatat ccgtcagcgt tttaccgctg cgtattaata
    14341 taacgaatga ttggtggaac attggaacac aggggccgta ctgcttgcag gacggccttt
    14401 tttcagctac catctttgcc ccggaactat tatattagcg ctataaccag ataaattgcc
    14461 acttatgatc ttaaggaaac cagcgctttt cagttgttta ctgcttaccg tactaaccag
    14521 ttaccagccc gctaatgctc aaaaaggcca acgcctgctg aagaatcacc ccggcgtggt
    14581 gtcttacacc taccgtaaag attttgcaaa ggatatgccc ggcaccctgg acatggtgaa
    14641 gaagaacggg tttacagata ttgaattctc taaccttttc ggccaaacgg cacaggatat
    14701 acgtaaatgg atcgatgaaa gaggcattaa atgctcctcc ttcggcgtga gttatgaaga
    14761 cctgaccacc aaaaccgacc aggtagcaaa aaatgcgaaa acattaggcg ccaaattcgt
    14821 acgcgtggcc ggttttccgc acagcaaaac cggtttaacg ctggatgagg ccaaacaagg
    14881 catttccgaa tttaaccgcg ttggtaaaat attaaaggac cagtatggcc ttaccctcat
    14941 ataccacaat cacggttttg aatttcagcc gtatgagaaa ggtaccctgt tcgattatat
    15001 tgtacagcaa accaatcccc gctatgtgag cctggaaatg gatatcctgt gggtattctt
    15061 ccccggccag gacccggtag ccctgctgaa aaaatatggc aaccgcttta aggccatgca
    15121 tgtaaaagac ctgaagaaag gagtggaagg taacctgtcc ggcggtacca acccggaaaa
    15181 tgatgtggcg cttggcacag ggcagatcaa cattccggct gtattgaaag ctgccaaacg
    15241 ctcagccatt gagcattatt acattgaaga cgaaagcagc aatgtggaaa cacaggtgcc
    15301 gcaaagcgtt caatacctgc tgggccttaa agagtagaac agcctttcca gtatgctcat
    15361 atcattggta agcacttctg caatacccgg taattgcggc tgtgagggaa tttgccgctg
    15421 ggccgttgtt aacaggccat ttgccagctg tatatccata gcataggcag tgtctaacgc
    15481 taccgcagat acgttgctga tatttccccg gatcatgcca aactcccgga aggggtatgc
    15541 cgataatttg atcaatactt tctgaccttt ttttaccttg ccggcgccaa acaccggcaa
    15601 ggtagcttta gccacatagt gctgcaccgg cggcactatc atcaacactg cttctccgct
    15661 gcttacaaac tggtgcgctt tccagaactt aaaaaagctg accttaccgg ctaccgggct
    15721 ttttactaaa tattgctgct cccatacttc cagctgtccc tgtaattgct tcacctgttc
    15781 ccgtactttt tgctgcaggt cattttcctg ctgaagggat tgttgctgca gatccgtaat
    15841 ggtttttaag tattcagttt gctgcagctt gttttgcagc aggttggcgc gggtagcatc
    15901 tgcagtcatt tgtttgtcca gcagctggcg tttgctgtta tctaattcca gcggtgctat
    15961 tactttttcc ctggccagct gtgaatctat tttaaagcgc ttttgttcca gcatcagctg
    16021 ttgctgcagc attacgtcct tgcgttgtaa ttcttcattt agctggtgct gagtagttag
    16081 ctgtgattgc agctgtgcta ccttttgcgt ggtaaaatgt ttgtcggtga aaaaaaggta
    16141 ctggttcacg gcctggtaca gcgcagcata accgccttgc aaagcgccca gctgcaaagg
    16201 ttgcgcaaag ttaaaccggc gcagggtagg ggccaggtta aaggaagtgt ccagctggtt
    16261 cagtaaggtt tgcagcaggc ggatgtcatt atagcgggct gcattttcca ggatgtaaat
    16321 gggcgcattc tcccgcacag cggcattgtt ctgtacaaac agctcactga tcttaccgct
    16381 ggtttgcgct actattttta caggtgggtt ggcagaggtg atattcacct gggtagtgat
    16441 cacatccggg taatgaatga aatacgcccc ggcaaataac agcataacaa cggcaaacag
    16501 cagggtaatg ccccggcgca cgatccagtg cggcattttg ctcataatat cctgtacttc
    16561 ttcgtgatgg tgttgatact gcggcataat aatgttttta atctcccagt tccagctggt
    16621 tctttaccag ctcaaaatat tttcctcttt tgcgggtaag ggtttgatgg ttgcccactt
    16681 ccacaatgcg gccctgttcc agcactacga tctggtctgc atgttttacc gtgcttaagc
    16741 ggtgcgcgat cactaccacc gtcttaccct ggaaaaattg ctgcaggttt tctatgatga
    16801 tcttttcatt attggcatcc agcgcgctgg tggcttcatc aaagaacagg tattgcggat
    16861 ctttatatac tgcgcgggca atgagcaggc gctgtttttg cccggtgctt aacccattgc
    16921 cgatgttgcc tattttggtg gcaaaacctg cgggcagctg ctgtataaag ttttcaatat
    16981 tggctacccg tgcggcatgc agcagcctgc gctcgttgat cttttcatcg cccacggcaa
    17041 tgttacgggc aatggtatct gaaaaaataa atccttcctg catcactacg ccgcactggc
    17101 gccgccacca tttgggcgag agcccggata gttccgtatg ccccaccagc agcttgccgg
    17161 ctaccggttc ataaaaacgt aacaacattt ttaacagggt ggttttaccg ctaccgctgc
    17221 tgccaacgat agcggttacc ttcccttcag gaatattgag gttaacatct tttagcacat
    17281 aggggctgct gccgctgctg tactggaaag aaagattgtc cagctgcaga tcgccatttt
    17341 gtaacagggg tgtttgcagc gtaaatgtat ctgtaacagt tgcaggttct tcgttatcgc
    17401 ggttatgaat ttctcccagt ctttccaggc tgatacgcgc atcctgcgca gagcggaaaa
    17461 aggccagcag ctgttccaat gggctgttca tttgccctat catatagctt acgcccagca
    17521 gcatgcccag tgtcatttgc ccgctcacca cttcgcgcgc tgcaatgtag gagatgagaa
    17581 tattcttcag ctgtgaaaag aacaggttgc cggtttgctg gtactgttcc agcgtaaggc
    17641 tgctgatatt aaggcggaac aggcgggcct ggatgcgttc ccattcccag cgctttggtg
    17701 tttcacagtt attgagcttt atttcctgca tgccggtgat caattcatac aggctgttct
    17761 ggttattact catttgctga aagcgtttat agtccagctc tttacgcttt tgcaaaaaga
    17821 aaacgatcca tacaacagac agcacactgc ctaccaggaa gatgaacagg atctttaagc
    17881 tataaatgcc cagcaccacg gaaaatacca gcaggcttac aaaagagaac agcgtatgca
    17941 gcgtttgcgt ggtcaggaac tgctcaattc tgccgtgatc attgatgcgc tgcgtaatgt
    18001 ccccgatcat ttttgcatca aaaaagcgga taggcagctg catgagctta gtcaggaagt
    18061 cggatataat agacatattg atacggctgt tcatatgcag cagtatccag ctacggatca
    18121 tttccactgc tgtggtgcca ataaacaata ccagctggga taccagcacc agctgaataa
    18181 aacccatgtt ctggtaattc acaccatagt caaccaggct ttgggtaaga aagggcagta
    18241 ccagcgccag taagctgccc agtaacatgc ccagtaccag ctgggttata tatttacgat
    18301 aaggtgttaa atactggaac aggaactgaa agcctttacg ggctgcggca tcttcctcat
    18361 gctggtaaaa aagcggggtg ggttccagca tcagcacaat accttgcgca tcttccttac
    18421 tggcccagct tttcaggaag gcagccttgt ctatttttac cagcccatgc ccgggatctg
    18481 caattaataa tttatcgctt gctttattac tgttatagtt ctgcgggggc agtacaacat
    18541 aatgatcctg gttccagtgc agaatgcagg gtaacgcaac ttctttatcc agctgctcaa
    18601 aatttaccgc tgctgctaat gtacggaaac cgatcttttc tgctgcttcg ctgatgccca
    18661 gcagggatac accttcgcgg ctcatgtcgc tcatttgccg cagactgtca agtgagtaat
    18721 ggcgtccgta atgtttggcg atcatgcgca aacaggtagg gccgcagtcc atagtatcta
    18781 attgtttgta gatggggaaa cgcatatagt taaaagatca gccgcgaagg tagcaggatg
    18841 gctggcgcgc gggctccctg taaagggtga ttttttaaat aataaagatt tatcctgctg
    18901 ttttataaaa tcaccttttc cggggagata gtcttgccgc ggtgcctata cttttgtgct
    18961 atcattattt cattaaccac tcacaattaa agtttttact gctttttaag attacaaaag
    19021 cattctgtgt catgaaaaaa caatcccaaa agaaattaac cctgggaaaa attactgtag
    19081 ccagcctcac taaagcggat cagcaaatgg taaaaggcgg tttgccaatt gatttcacaa
    19141 agagaagcgt atgcgcagac gcttgttgcg ccagcgacat taacgcgcag tgccgtaccc
    19201 tgtaattgtt aaggcattca tttgcaaaac acacttcatg catgtggagt gtgttttgtt
    19261 tttaacccct cattattttt atgaaacagc tatataagat actggcagat atcagcaccg
    19321 cgctggatca ttttattgag caggaaacag atcccggcct gctaagcggc tatggtggct
    19381 gcgccttatt ttatgcttat taccatcgct tgacgggcaa ggaggagtac ctgcataaaa
    19441 tggagctggt ggtaatgaaa gccctgcatg caatggctac ggaagaaatg atccattcac
    19501 attgcagcgg tgtggccggt atcagctggt gtttacagca tttaatgcag cagggcttta
    19561 ttgaaaagga agaaggcgcc aatgcttttg aagaaaccga tgcgctgctg taccggtata
    19621 tggaccagga gctaagtgaa atgcgctacg atcttttaca tgaaggctta ggccctgcct
    19681 tgtatttcct ggagcgcgaa gcggaacctg cgataaatgt ttatctggaa aacgttgtta
    19741 cccggctgga aaaggctgct gtgcctatgg ctaccggcat tagctggaaa gatggttttg
    19801 tgaaaaaaga ccaggagggt gatcattata acctgggcct ggcccatggt atgccggcca
    19861 tactggcggt actgggaatg atctatgaaa ggggtatagc gcaggaacgc gcccggtctt
    19921 tgctggaaaa gggtatacaa tggttattaa ctacccgtaa tcaaaacatc agcaccggca
    19981 tgtcctgtta cccaaccatg gtaacggccg gcaataaacc tgttggcaac ccgcaaagcc
    20041 gcctgggctg gtgctatggc gatcctggta ttgccattac cctatggaac gccggtgtgc
    20101 gcctgcagaa cgaaagtttt aaacaggagg cctgcgatat cctgctacag accatgcagc
    20161 accgcgatgc agaaaatggt agtgtgcggg atgccggctt atgccatggc agcatggggc
    20221 tggcgcatat ttataaccgc atgtacgctg gtagcggtaa tgagctgtta cgcaggggca
    20281 tggaccactg gctgcagcaa accctggctt tccgtacctg ggccgatggg ccggctggtt
    20341 ttaaatgcca tactatgagt ggtaaggtga acagctataa cctgctggaa ggtattaccg
    20401 gcatcgggct ggccctgatg gccattgcag atccacaggc ggcagcctgg gaccgatgca
    20461 tgctgctatc ctgattagtt ggaaaaatgg ggaacaattt tgtagctttg aaaacagctc
    20521 ataacagtat atggtacgcg ttttcattgt cgatgatcat cccctggttt tagaagggtt
    20581 acgtttcctg cttggctccg aaaaagacat tcaactcacc ggacatgctc ccaatggcca
    20641 ggcctgcctg gactatttta cagaaaataa agcagatgtg atcctgatgg acattggcct
    20701 gccggatatg agcggtatag acctgtgcgg catgatcaaa acaaaatacc cccaggtaat
    20761 ggtgctggcc ctcagctcct ttaacgatgg ccaccacgta aaacaaatga tggacaaagg
    20821 cgccagcggc tatgtgatca agaatgccga taaggaagtg ctgctggaag ccattagtga
    20881 agtaaataaa ggtaaaacct acctgtgctt tgaagccggc catgctgccc gcaaagaaga
    20941 tgataacacc cttaacaaat tacccccttt aacccgccgc gaaaaagaag tgctgcagct
    21001 gattgcggaa ggttacacga accctgaaat agccgaaaaa ttattcgtca gcgcatctac
    21061 tgtagatacc caccgcaaaa gtctgctcgc caaactggat gtgaaaaata
//
