LOCUS       NZ_FOBB01000004        23075 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Chitinophaga rupis strain DSM 21039, whole genome shotgun sequence.
ACCESSION   NZ_FOBB01000004
VERSION     NZ_FOBB01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga rupis
  ORGANISM  Chitinophaga rupis
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900109685.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 15:41:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,474
            CDSs (total)                      :: 6,410
            Genes (coding)                    :: 6,392
            CDSs (with protein)               :: 6,392
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 18
            CDSs (without protein)            :: 18
            Pseudo Genes (ambiguous residues) :: 0 of 18
            Pseudo Genes (frameshifted)       :: 4 of 18
            Pseudo Genes (incomplete)         :: 13 of 18
            Pseudo Genes (internal stop)      :: 2 of 18
            Pseudo Genes (multiple problems)  :: 1 of 18
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:12:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 342643
            Orig. end                         :: 365718
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FOBB01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23075
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..23075
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23075
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13075](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13075
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    225..241
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.98"
                     /tool="antismash"
     misc_feature    complement(365..379)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.98"
                     /tool="antismash"
     gene            complement(422..787)
                     /locus_tag="BMZ54_RS18260"
                     /old_locus_tag="SAMN04488505_104277"
     CDS             complement(422..787)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018611081.1"
                     /locus_tag="BMZ54_RS18260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104277"
                     /product="response regulator"
                     /protein_id="WP_089915051.1"
                     /transl_table=11
                     /translation="MGSILIIDDDSRNIFALTAVLKARGFHCETATGMQEAFELLAAGN
                     TIGIILMDMMMPDMDGYEAIPILKASPQWQHIPVIAVTAQAMAGDRDKCLAAGADGYIS
                     KPVDIDKLQQLLDEYVR"
     gene            complement(811..4413)
                     /locus_tag="BMZ54_RS18265"
                     /old_locus_tag="SAMN04488505_104278"
     CDS             complement(811..4413)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012793160.1"
                     /locus_tag="BMZ54_RS18265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104278"
                     /product="response regulator"
                     /protein_id="WP_089915054.1"
                     /transl_table=11
                     /translation="MNESFKRNLIITYGLSLFLVIISSVASYMSIHNLLEGQGLVDHTN
                     NVIMKLEQISSALKDGETGQRGYLLTGKTEFLDPYNGARDRALTALNEVEKLTLDNASQ
                     QQSLQQLRDLVVRRFALLRDIIDAKKRGVANNEQDLTLGKVQMDEIRRLVTTMQDREQA
                     LLTQRTEKTNRFAAYTPVLIVIASLLSLLVAIVSFLRVNADYDRRVVLQRALEQKDIDT
                     SNRLAIIQGIADKISGGDYQVRVSDEGKDVLGSLGVALNKMAQSLDYSFATLSHKEWTQ
                     TGIASLNEKMIGEKQLDVLTYNIIEFITDYTSSQVGAVYLMKDEETLGLTASYGLNKDS
                     VKKTLFLGEELAGQAALSRKDLLLENITDAALVVNHTAGSIKPQSIIAVPIIYERRLKG
                     VIELATLGTYSPVVREFLKIASYNIGQAIHSAKDHQRLQDLLAETQAQSEELQSQHSEL
                     ENINTELEAQSQKLQASEEELRVQQEELQQANQELEERSRLLEEKNELILERNFEIQAK
                     AEELAQTTKYKSEFLANMSHELRTPLNSILLLSRLLSENHAGNLLSDQIEYATVIRSSG
                     NGLLTLIDEILDLSKIESGKMELEYEFVDIESVTGEMSSLFGPIAKDKNITFRIAAADD
                     LPKMLETDRLRLQQILRNLISNALKFTARGAVTLHISKDAHTISFAVQDTGIGIPADKQ
                     QTVFEAFQQADGSTRRKYGGSGLGLSISRELAKLLGGEISLESEEGKGSTFTLTLPLQK
                     GASIHPAKPIIPAPVQEEITASQQEKPKEDELMKDPQFLSAHIPPAVPDDRDTITAGEK
                     VILIIEDDTAFARSLLDYTRQKGYKGIVAVRGDEGVELARRFRPLGILLDIQLPVKTGW
                     EVMEELKADAATRPIPVHMMSSYQAKTRSLSRGAVDFINKPVDIDKLSDVFQRIEQALS
                     RHPKKVLIVEENQKHAQALAYYLDGFNVHTQIRTTVGDGITALNRSEVDCVILDMGVPA
                     QHSYDVLEEVKKSPGYENLPIIVFTGRNLSHVEEMRIKQYADSIVVKTAHSYQRILDEV
                     SLFLHLVEENTKDRGVTRYKRMGALSEVLKGKVVLVADDDVRNIFSLTKSLEAYGMKVI
                     SAIDGREALKQLDETPNVDLVLMDMMMPEMDGYEATRRIRQMHKYRNLPVIAVTAKAMT
                     GDREKCINAGASDYITKPVDVDQLVSLLRVWLYE"
     gene            complement(4424..5626)
                     /locus_tag="BMZ54_RS18270"
                     /old_locus_tag="SAMN04488505_104279"
     CDS             complement(4424..5626)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018611086.1"
                     /locus_tag="BMZ54_RS18270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104279"
                     /product="response regulator"
                     /protein_id="WP_089915057.1"
                     /transl_table=11
                     /translation="MILIVDDKQENLYSLKALLRLNLYEVDTATSGEEALKRILRNEYE
                     LIILDVQMPGMDGYEVAETITGYSRSKDIPIIFLSAVNIDKRFVTKGYASGGVDYITKP
                     FDADILLLKVKTFTRLYRQTKELNDIKETLEQKVEERTKALVQANKELELSNAELQQYA
                     FIASHDLQEPLRKIITFSRLVIERFLGGDPEALQYMNKVISSSERMRSLINDLLSYSHL
                     AEPPRFNICNLNQLVQETMADLEVAIKEKEAVLHISHLPSIEAIPDQMRQLFQNLVSNA
                     LKFAKKDTPPVIKIWSELIDQRSLTAGISGKGAWCRIYISDNGIGFNEMYLDKIFHMFQ
                     RLHGKDEYHGTGIGLTIVKKIIQKHNGLISAESREGQGATFMLVLPLKQTAILETETQG
                     L"
     gene            complement(5661..6113)
                     /locus_tag="BMZ54_RS18275"
                     /old_locus_tag="SAMN04488505_104280"
     CDS             complement(5661..6113)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="BMZ54_RS18275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104280"
                     /product="response regulator"
                     /protein_id="WP_089915059.1"
                     /transl_table=11
                     /translation="MKNPTTFLLVDDDLDDTSLFEEVLQQVDPAVVFASAANGHEALAA
                     LREGTTRPDVIFLDLNMPRMDGRQCLAALKEDDTLKQIPVIMYTTSSQPKDVEQAMQKG
                     AVSFITKPTSLKELQEILEAIAGNVHLDLHAALKTLRQTVPACVIC"
     gene            complement(6305..6811)
                     /locus_tag="BMZ54_RS18280"
                     /old_locus_tag="SAMN04488505_104281"
     CDS             complement(6305..6811)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BMZ54_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488505_104281"
                     /product="hypothetical protein"
                     /protein_id="WP_089915062.1"
                     /transl_table=11
                     /translation="MLLPSLFCIQLCACKPVIPKKPEQRRPDTTMIPSADTMIPVPDTI
                     MADEITSWSRFEDYIGRYAGEVDLLDKEPLKERFHRLLNRDSLLFFQRFQVAPPIEIEG
                     NIFYNEGCQPHNCGMDEAALVIDMNRDIIYAGIAVKGRVKIFAEKKDTAYPQRLREWKQ
                     KFQAK"
     gene            complement(6903..7682)
                     /locus_tag="BMZ54_RS18285"
                     /old_locus_tag="SAMN04488505_104282"
     CDS             complement(6903..7682)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (11-251). E-value: 3.2e-83. Score:
                     270.7. Matches aSDomain:
                     nrpspksdomains_BMZ54_RS18285_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012793874.1"
                     /locus_tag="BMZ54_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104282"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_089915065.1"
                     /transl_table=11
                     /translation="MQPEFIIVHQQVATHVAHIQLNRPNALNALNLQLMTELKTALQTL
                     DADDQVRAIIISGNEKAFAAGADITQMAGKSAIDMYNTDQFSTWDAIKKTKKPIIAAVS
                     GFALGGGCELAMLCDMIVASETARFGQPEIKLGVMPGAGGTQRLTRAVGKALAMEMVLT
                     GRFITAAEALQAGLVNRITPVELYLEEAIKLAKEIAGMSPLATKMAKEAVLKAFDSSLE
                     EGLHFERKNFYLLFASDDQKEGMQAFIEKRAPRFTGK"
     aSDomain        complement(6930..7649)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BMZ54_RS18285_ECH.1"
                     /evalue="3.20E-83"
                     /label="BMZ54_RS18285_ECH.1"
                     /locus_tag="BMZ54_RS18285"
                     /protein_end="251"
                     /protein_start="11"
                     /score="270.7"
                     /tool="antismash"
                     /translation="VATHVAHIQLNRPNALNALNLQLMTELKTALQTLDADDQVRAIII
                     SGNEKAFAAGADITQMAGKSAIDMYNTDQFSTWDAIKKTKKPIIAAVSGFALGGGCELA
                     MLCDMIVASETARFGQPEIKLGVMPGAGGTQRLTRAVGKALAMEMVLTGRFITAAEALQ
                     AGLVNRITPVELYLEEAIKLAKEIAGMSPLATKMAKEAVLKAFDSSLEEGLHFERKNFY
                     LLFASDDQKEGMQAFIEK"
     gene            complement(7691..8842)
                     /locus_tag="BMZ54_RS18290"
                     /old_locus_tag="SAMN04488505_104283"
     CDS             complement(7691..8842)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023828.5"
                     /locus_tag="BMZ54_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104283"
                     /product="DUF3667 domain-containing protein"
                     /protein_id="WP_089915068.1"
                     /transl_table=11
                     /translation="MKTQPLREDKHCLNCGTEVPERYCTHCGQENAVPHESFGHLVKHF
                     VGDVLHYDSQFLQTISYLLFRPGRLTKEYMAGRRVAFVNPIKLYIFVSFVFFLTWAMLS
                     HDSHEKNEKRSAEKEAAAKQHEEDESQKIPSITGILGAVKDSLKNNKELARAVDSLAYR
                     YRYDSARSHNAVAPVAAGSHDTAAARHTAAKAEEDDDLRLTDSEDDPRNKYGNEEAYDS
                     AQAAMPKAQRDGWLKRYFTHKWMRLNPGDDRLQENLSESLKHHFPKMMFVLLPLFALWL
                     KLIYNWKRWYYTDHAIFALHVHCFAYTVLLLAYILEKLTGVDGFIGWSVWLIFGYLVLA
                     LRNTYHQSFMRSFGKSLLLLFGYGISFAFVGVFFILIIFAVIL"
     misc_feature    8924..8938
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.37"
                     /tool="antismash"
     gene            8986..9852
                     /locus_tag="BMZ54_RS18295"
                     /old_locus_tag="SAMN04488505_104284"
     CDS             8986..9852
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BMZ54_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488505_104284"
                     /product="RHS repeat domain-containing protein"
                     /protein_id="WP_089915071.1"
                     /transl_table=11
                     /translation="MMHIKKYCLLAGCLLLFTARSMAQYYYQDIYNTRQTSSNMAQLKE
                     NNVRVQEVQSLDASMETDNDFRCQRILSPNFRQMRAITQSRGTGLSIMTSTFSAKGTLM
                     KTTDSTESSITTIQYKYDTAGRLTDIHTSSLSEAGSSKFRVTETRTYLYDEKGHLASMI
                     HKKSLGGNDSTTVLFKTDEQGHVIEEQEYGKNMRSPRIYYNYDAQGRLTDVLRYHTGKK
                     RMLPDYMFEYDAQQRLSQMTTVNAETADYTVWKYKYDEKGLPLREECYGKEKALLGIVK
                     YNYEFLK"
     gene            10001..13075
                     /locus_tag="BMZ54_RS18300"
                     /old_locus_tag="SAMN04488505_104285"
     CDS             10001..13075
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="BMZ54_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104285"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_089915076.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 9.5e-165,
                     bitscore: 544.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 5.3e-07,
                     bitscore: 25.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.8e-62, bitscore:
                     204.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METPFTFCDNLVIRVPRLPFQPHFEAATVQQLLTDAAFLESVYIA
                     SPVLYDEAVRLREGQLHTAKEQAKVTDALVKYYTRSYSRCTPFGLFSSCTTLPWAQTPS
                     PADFKAMPLQRRTRLDMYYLGALAQELLQLPSIRERLLFFPNNSRYVMGNELRYMEYEY
                     VENKRFYRISAVEHQPALQTVLAAAEKGATLFELCALLTVPGPDALDYINSLVTAQVLV
                     SELEPAITGPAFLTQLLTVLQRLQAPAAPVLEQVQAALQALDAQDTNPIAAYEHIIQLI
                     TQLQIPFEAGKLLQVDAFRPAAAGGGVPASLQADLSGALDILHTLHQYKGGNIPALQTF
                     IEKFYARYADEAIPLVQALDAESGIGYPAGTAASFAPLVDGLPIPAQTDTPARTLTATD
                     EWLLAQLTRCLHTGQQELVLDDAVIPRSADHTETFPPSLSAVFRLLDAASGHLQLEGFF
                     GPSAAGMLGRFAYGDSQLHDLTLHITQEEQRLNEGVIFAEIIHLPDNRTGNVILHPAFR
                     EYEIPYLAQSSLPAERQIPIQDLYLRVVDQQLQLFSKKLDKQIIPRLSNMHNYALHALP
                     IYYFLCDLQKQGLHTAYLFEWKTQPFRFTFLPRVRYKNIVLSVAQWQLEQADISDLQQS
                     TMEALPAAVQRFREQWQLPQLLVLADGDHELLIDLDNLYTVQAWLRTVKQRTTFTLKEF
                     LPGTGDYVQQCVAPMIKTTATYNPVREPVETIITPGIQRSFPVGSEWLYYKLYCGPSLA
                     DNILTEQVRPVIETLTAAGIIDQWFFIRYLDPDFHLRIRFHLTDSRLAGEAIALLSQAL
                     APLQASHMIWKTRLDTYKRELERYGGAAAMALSEKLFFYDSQTTLELLAMLSGDEQEKI
                     KWLWALKGMDTWLNDLQLDATEKRAFILQQKTAFAQEMQVDKPMRQRLNQQYEQHAAYI
                     HEIMEAITPQNRFYPVLQLLEARSQQVAPLAQQLIQLRQQGRLNVNWFHLTGSYVHMMI
                     NRIMTSKPRQYEMALYDILDRYEARKYYLANIQKG"
     aSDomain        10430..10684
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BMZ54_RS18300_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.90E-08"
                     /identifier="RREFam001.1"
                     /label="BMZ54_RS18300"
                     /locus_tag="BMZ54_RS18300"
                     /protein_end="228"
                     /protein_start="143"
                     /score="25.3"
                     /tool="antismash"
                     /translation="FPNNSRYVMGNELRYMEYEYVENKRFYRISAVEHQPALQTVLAAA
                     EKGATLFELCALLTVPGPDALDYINSLVTAQVLVSELEPA"
     gene            13130..13327
                     /locus_tag="BMZ54_RS18305"
                     /old_locus_tag="SAMN04488505_104286"
     CDS             13130..13327
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BMZ54_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488505_104286"
                     /product="hypothetical protein"
                     /protein_id="WP_089915079.1"
                     /transl_table=11
                     /translation="MSVKSQQTKFSLDVLANWDKQSHEKLAMHKRTIANVSETAVTGRK
                     GKQTDSILHQPTTTVISTSH"
     gene            13386..13583
                     /locus_tag="BMZ54_RS18310"
                     /old_locus_tag="SAMN04488505_104287"
     CDS             13386..13583
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BMZ54_RS18310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488505_104287"
                     /product="hypothetical protein"
                     /protein_id="WP_089915082.1"
                     /transl_table=11
                     /translation="MSVKSQQTKFSLDVLANWDKQSHEKLAMHKRTIANVTENVVTGRK
                     DRQAQALHTSPTTTVISTSH"
     gene            complement(13999..16467)
                     /locus_tag="BMZ54_RS18315"
                     /old_locus_tag="SAMN04488505_104288"
     CDS             complement(13999..16467)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013438.5"
                     /locus_tag="BMZ54_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104288"
                     /product="glycosyl hydrolase family 8"
                     /protein_id="WP_202909283.1"
                     /transl_table=11
                     /translation="MRKPYAILATGMLCIAGLIVQAQKKPFPQAVSYPGCIKPNNVTQA
                     DMNTSVASFYDYWKSKYLKNNLASLPGGYYIKGEISGDADGYTPLGSSEGQGYGMVITV
                     LMAGHDANARTIYDGLFKTARAYRSSINSNIMGWVVADNASAQGHFDSATDGDIDIAYS
                     LILAHYQWGSDGAINYLNEAKKMITNGIKAANVTTTNRLNLGDWDSKSALNTRPSDWML
                     SHMRAFYQETNDAAWLNLINNLYSVYNQFSATYSPSTGLISDFVVKNPPEPAPKNFIDE
                     GPQTNEYNYNACRVPLRVVMDYALYGSTSAQTISNKIATWIIQKSGGNPASIRDGYQLN
                     GTTSGTDPEAVFVAPFVAAAVANSANQAFVNSGWNFLKTKKSGYYSDSYSLLCQLFISG
                     NWWKPEAGTTPPPACVPASASSDDGNVATNVLDNDLNTRWSASGDGQWIQLCLDNPVSV
                     TGVDIAFYQGNTRRALFDVQTSTDGLTFTNAATGLQSSGTSLALESFTFAAKTAKYVRI
                     LGHGNNVSAWNSYTEVKVRTGTQSGQQVTLSAAKDAYVRNGVYADSAYGALDPVNLISK
                     LNSTTTTGNDRQAYLGFDLSSVSGTITSAVLKVYGHQDDNRVTNVPVGAYPVANTTWTE
                     AGITWNNKPAPGATALATATVTDSIGRYYSWDITAYVQSEKAAGRSAISLALLNGLMAN
                     PRTLWNSKETGSNAPQLVITTTSTAKTAARQAFVASPSDTHGDKLQQVSVFPNPLSSNA
                     TVAFTLQQAGPVHLAVYNTNGEVVKVLANEQLPAGRHTRTFAPGNMPGGLYVLKLVHNG
                     KVSTVKLVKQ"
     misc_feature    complement(16550..16565)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.08"
                     /tool="antismash"
     gene            complement(17157..17429)
                     /locus_tag="BMZ54_RS18320"
                     /old_locus_tag="SAMN04488505_104289"
     CDS             complement(17157..17429)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012792865.1"
                     /locus_tag="BMZ54_RS18320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104289"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_089915088.1"
                     /transl_table=11
                     /translation="MSQPELCKHLQSIEEIKTAEKYECAECVKHGGQWVHLRTCQTCGV
                     TLCCDDSPSQHMSHHQHETGHPVISSAEPGERWLWCYKDDAFAEY"
     misc_feature    complement(17457..17475)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 23.4"
                     /tool="antismash"
     gene            complement(17568..19232)
                     /locus_tag="BMZ54_RS18325"
                     /old_locus_tag="SAMN04488505_104290"
     CDS             complement(17568..19232)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012789016.1"
                     /locus_tag="BMZ54_RS18325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104290"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_089915091.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.1e-32, bitscore:
                     106.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQPLIFCIDDDEQVLRAIVRDLKSQYRKNYKIISTTTVNEALDS
                     LLELKNKGETIAMFISDQRMPVMEGVDFLEKAMQFYPEARRVLLTAYSDTDAAIKAINS
                     VQLDYYLVKPWGPPEEKLYPVIDELLDDWQHIYHPVFKGIKVVGYQFSQQSHAVKDFLA
                     GNLIPYQWLDVQTTSDANRLLELNNLSLKELPVVFFEDGSYLVTPTIMEIAGKVGLNPH
                     VKHDVYDVVIIGAGPAGLAAGVYGASEGLKTLLIERRAPGGQAGTSSRIENYLGFPTGL
                     SGAELTRRAIAQATRLGTEFITPQSVKDIQQKDGYNKIILEDDSVINTRSVIITTGVDY
                     RKLDTQGVDQFTGAGIYYGAAMTEATACKDKEVYIVGGGNSAGQAAMYLSKFAKNVYIL
                     IRKDDLSSTMSAYLIEQIKGASNIKIRPRTEIAEAIGTDKLEKLVIKNVETGETCTEAA
                     DALYIFIGAKPFTDWIALNIIKDDKGFIETGRELKKYDAFGKIWKQQRDPYLLETSCPG
                     IFAAGDVRASAMNRVAAAVGEGSMAISFVHKYLAEVK"
     gene            complement(19300..20700)
                     /locus_tag="BMZ54_RS18330"
                     /old_locus_tag="SAMN04488505_104291"
     CDS             complement(19300..20700)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012789017.1"
                     /locus_tag="BMZ54_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104291"
                     /product="sensor histidine kinase"
                     /protein_id="WP_089915094.1"
                     /transl_table=11
                     /translation="MNQVTVEWLRTIEAIKDVPAEQLQWMIDNSQHYIIPPGGFLFEPE
                     TAIWATHFIVTGRIRVYRLQNNEARELAIWPARSIAGYLPFSRGKVAAAFGEALEDVQI
                     MSLPIEKSPELIRTHFELTQALVHMMTDRVREFTSFQQQNEKMMALGKLSAGLAHELNN
                     PAAAIVRGAESLKKHLQLEPTTFREIMAIKATPEQVDMVSKLLFSILHGTEKPVLTLMQ
                     RSDKEDELLDWLDDHNVANSQEVAENMVEFGFTLENLEEFKQHIQEKDLSPVFNWINSN
                     LVKERMVLDIEEASKRIATLVGSVKVFTHMDQGHDKELTDIHSGIRNTLVILQHRLRKG
                     NVELVENFDNTLPQIKALIGEMNQVWTNLIDNALDAMEPNKKGVLEIQTSKDRHCVYVS
                     IIDNGPGIPEEIRSRVFDPFFTTKGIGKGTGMGLDIVMQIVRQHNGNVKVISEPGRTEF
                     KVSLPIQG"
     gene            20827..21777
                     /locus_tag="BMZ54_RS18335"
                     /old_locus_tag="SAMN04488505_104292"
     CDS             20827..21777
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014376.5"
                     /locus_tag="BMZ54_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488505_104292"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_089915097.1"
                     /transl_table=11
                     /translation="MSKDAIRLDISTTVKHYLAADNNAPQGFGIEKYTDLQAGDFAILS
                     NEGGRHNGPPVKTDHFALVLCMRGHGVKTIGHHTFEVTPQSIHIVSPRDLHSFENASDD
                     LLLYMILFRHEFVAHTFIKEQILDQLLELPPELPPIYHLDEREFTSIRDLFIKIEREYR
                     EAPAYFLQMVRLLVVELLYEINRAHERALQQPTKPAGRPLQLVAAFKKLVEAHFLTIRT
                     VQQYADLLHVSAKHLSEQVKHATGENALTIIHQRIFREAEYLLHTSDFSIKEIADQLNF
                     DTSSHFSRFFKHFAGVNPSEFMVKKDTGNRRISNK"
     gene            22112..22690
                     /locus_tag="BMZ54_RS18340"
                     /old_locus_tag="SAMN04488505_104293"
     CDS             22112..22690
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BMZ54_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04488505_104293"
                     /product="outer membrane beta-barrel protein"
                     /protein_id="WP_089915100.1"
                     /transl_table=11
                     /translation="MKKTIKTGIMGLLLLTGLTLSSKAQDASKKVTAERPAFLLSVGPE
                     ANLPLGDFKDAYDWSIGGSVQGDYAILKRDLYVTLNAGFSDFMAKDIAGFSAKDLQLIP
                     VKAGLKYYPVSNFYVQAQAGAVFIANKSDVLADKSAAFAYSPQVGYLFHLGNGSYLDAG
                     VKFEGYSKFADGGSSNNVLGLRVAYAFGL"
     misc_feature    complement(22113..22127)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(22868..22882)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.59"
                     /tool="antismash"
     misc_feature    complement(22941..22950)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.22"
                     /tool="antismash"
     tRNA            22952..23024
                     /anticodon=(pos:365628..365630,aa:Gly,seq:gcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BMZ54_RS18345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN04488505_104294"
                     /product="tRNA-Gly"
     gene            22952..23024
                     /locus_tag="BMZ54_RS18345"
                     /old_locus_tag="SAMN04488505_104294"
ORIGIN
        1 tgttgggttc aggtctgttg catatagcag tgatttatgc agcaggttag cctcatccag
       61 caggatggcc atggaatata cctcctcccc tgtggcacag ccggcatgcc agatgcggat
      121 aaagggatgc gtggccagta taggcagcac ctcttcccgg atggtcttaa acacctgggg
      181 atcgcggaac atttccgtta cattcaccgt tagctcctct accatgcggg taaggtaggc
      241 aggatcctgg cgtacacggt ataacagctc tgcaaaactg gggaagcggt ctatgatcat
      301 caggcggctc acccttcttt ttaaagaagc gcgggcgtag ttggtgaagt cgtagccgta
      361 gctgcggaac aattcgtcca gcagcaggtc cagctcttca tccttcacac tattttccat
      421 tttatcgaac atattcatcc agcagctgct gcagtttatc tatgtctacc ggttttgaga
      481 tataaccatc ggccccggcg gccaggcatt tatccctgtc gcctgccatg gcctgtgcgg
      541 taacggctat taccggtatg tgctgccatt ggggcgatgc tttgagtatg gggatggcct
      601 catacccatc catgtccggc atcatcatat ccatcaaaat gatgccaatc gtatttccgg
      661 ctgccagcag ctcaaacgct tcctgcatac cggtggccgt ttcacagtga aaacccctgg
      721 ctttcagcac ggcggtgagg gcaaaaatat tcctgctgtc gtcgtctatt atcaatatgc
      781 tacccattcc cttatatatt gcttttggag ttattcatat agccataccc gtaacaggga
      841 caccagctgg tctacatcca ccggtttggt aatgtagtcg gatgcgccgg cattgataca
      901 cttctcacgg tcgccggtca tggctttggc agttaccgct attaccggca ggttgcggta
      961 cttatgcatt tgcctgatgc ggcgcgtggc ttcataccca tccatttccg gcatcatcat
     1021 gtccatcagc accaggtcta cgttgggcgt ttcatccagc tgcttaaggg cttccctgcc
     1081 atctatggcg gagatcacct tcataccata ggcttccagc gacttggtga gggagaagat
     1141 gttgcgcaca tcatcatccg ccaccagcac taccttacct ttcagtacct cgcttaaagc
     1201 gcccatacgt ttatagcggg ttacgccgcg gtctttggta ttctcctcta ccaggtgcag
     1261 gaaaagggat acctcgtcca ggatgcgctg gtaagagtgc gctgttttta ctacgatcga
     1321 atctgcatat tgcttaatgc gcatttcctc cacatgtgaa aggttgcggc ccgtgaatac
     1381 aataatgggc aggttctcgt accccggcga tttctttact tcctccaata catcgtacga
     1441 gtgctgtgcg ggcacgccca tgtccaggat cacacaatcc acctcactgc ggttaagggc
     1501 tgtaatgcca tctcctactg tggtccggat ctgtgtatgc acgttaaatc catccaggta
     1561 ataggccagg gcctgtgcat gtttctggtt ctcttccacg atcagcactt ttttcgggtg
     1621 acggctcagc gcctgctcta tgcgctggaa cacatcgctc agcttatcta tatctaccgg
     1681 cttatttata aagtctactg caccgcgcga caggctgcgg gttttagcct ggtaagacga
     1741 catcatgtgc acgggaatgg ggcgggtggc ggcatcggct ttcaattcct ccattacttc
     1801 ccaaccggtt tttacgggca gctgtatatc cagtaaaatg cccagtggcc ggaaccggcg
     1861 ggccagctcc actccttcat cgccccttac ggctacaatc cccttatacc ctttctgccg
     1921 ggtatagtcc agcagcgagc gggcaaaggc ggtatcatct tctatgatca gaatcacctt
     1981 ttcacctgcg gtgatagtat cacggtcgtc cggaacagcg ggcgggatat gcgctgacag
     2041 gaactgtgga tctttcatca gctcatcttc cttcggtttt tcctgctgtg aggcggtgat
     2101 ctcttcctgc accggggccg ggataatggg tttggcggga tgaatggagg cgcctttttg
     2161 cagcggcagc gtaagcgtaa aggtgctgcc cttgccttcc tcactctcca aactgatctc
     2221 gcctcccagc agcttggcca gctcccggct aatggacaag cccaggccgg agccgccgta
     2281 ctttctgcgg gtagagccat ctgcctgctg aaaggcttca aatacagttt gctgcttatc
     2341 tgccggtata ccaatgccgg tatcctgtac ggcaaaggaa atggtatgag cgtctttaga
     2401 aatgtgcagg gtaacggcgc cgcgggcggt gaatttcagc gcattggaaa taaggttgcg
     2461 caggatctgc tgcaggcgca ggcggtctgt ttccagcatt ttaggcagat cgtctgctgc
     2521 tgctatgcgg aaggtaatgt tcttatcttt tgcaatgggg ccgaacaggg agctcatttc
     2581 ccctgttaca ctttcaatgt ccacaaactc atattccagc tccattttac cggattctat
     2641 cttggacagg tccagtattt catctatcag cgttagcagg ccattaccgg agctgcggat
     2701 caccgtagca tattctatct ggtcgctgag cagattaccg gcatggttct ctgacaggag
     2761 gcgggaaagc agcaggatgg agttgagcgg cgtacgcagc tcatgcgaca tattggccag
     2821 gaactctgat ttgtacttag tggtttgggc cagctcttct gccttggcct ggatctcaaa
     2881 attgcgttcc aggatcagct cgttcttttc ttccagcagg cggctgcgtt cttccagctc
     2941 ctggttggcc tgctgcagct cttcctgctg tacgcgcagc tcttcttcag aggcctgcag
     3001 cttctgcgac tgggcttcca gctctgtatt aatattttcc agctcactgt gctgcgactg
     3061 caattcttct gactgggcct gtgtttcggc cagcaggtcc tgcaggcgct gatggtcttt
     3121 cgcgctgtga atggcctggc ctatattgta ggatgctatt ttcaggaatt cgcgtaccac
     3181 ggggctgtaa gtgcccaggg tagccagctc tattacccct tttaaacggc gctcataaat
     3241 gatggggact gcaataatac tttgcggctt aatactaccg gcagtatggt tcactaccag
     3301 cgctgcatcc gttatatttt ccagcaacag gtctttacgg gataaggcag cctgcccggc
     3361 cagctcctca cccagaaaca atgttttttt aacgctgtcc ttatttaatc catagctggc
     3421 agttagtccc agggtttcct catccttcat caaataaaca gcgcctacct gggagctggt
     3481 atagtctgtg ataaattcaa taatgttata ggtcaataca tccagctgtt tttcaccgat
     3541 cattttctca ttcaggctgg caataccggt ttgtgtccat tccttgtgcg acagggtagc
     3601 gaaggaatag tccagcgatt gtgccatctt gttcagtgcc acacccaggg agcccaatac
     3661 atccttccct tcatcactta cccttacctg gtagtcaccg ccggagatct tatctgcaat
     3721 accctggata atagccaggc ggttagaggt atcaatatct ttttgctcca gggcgcgctg
     3781 cagcactacc cttctgtcat aatcagcatt cacccgcagg aaggacacaa tggctaccag
     3841 cagggatagc agggaggcta tgacaataag caccggcgta tatgctgcaa aacggttggt
     3901 tttttcggta cgttgtgtaa gcagcgcctg ttcccggtcc tgcatggttg ttaccaggcg
     3961 gcgtatttca tccatctgca ctttacccag tgtaaggtcc tgctcattat ttgcaacgcc
     4021 tcttttttta gcatcaataa tatcccgtaa cagggcaaag cgccgcacta ccaggtcacg
     4081 cagctgctgc agggattgtt gctgcgaagc attatcgagc gtaagctttt ctacttcatt
     4141 cagtgcagta agggcgcggt cgcgggcgcc attataagga tctaaaaact ccgtttttcc
     4201 ggtgagcagg tatccccgct gcccggtttc cccatctttt aaagcagatg agatctgctc
     4261 cagcttcatg atcacattat tggtatggtc taccaacccc tgcccttcca gcaaattatg
     4321 gatgctcatg taagatgcga cagagcttat gatcaccagg aaaagggaca ggccgtaagt
     4381 gattattaaa ttccttttga atgattcgtt catgtatata cgtttatagt ccctgcgttt
     4441 ctgtttctaa tatggcggtt tgtttcagcg gcagcaccag cataaaagtg gcgccctggc
     4501 cttccctgct ttctgcggag ataaggccgt tatgtttctg gatgatcttt tttacgatgg
     4561 ttaagccgat gccggtacca tgatattcat ctttgccatg caggcgctgg aacatgtgga
     4621 atattttatc gaggtacatt tcattaaacc ctataccgtt gtcggaaata tagatgcggc
     4681 accaggcgcc tttgccggaa atgccggcgg tgagggagcg ctggtctatc agctcactcc
     4741 agatcttaat aacaggcggg gtatcttttt tagcgaattt aagcgcattg ctgaccaggt
     4801 tctggaacag ctgccgcatt tggtccggga tggcttcaat ggagggcagg tggctgatgt
     4861 gcagcacagc ttctttttcc ttaatggcta cttccaggtc ggccatggtt tcctgtacca
     4921 gctggttcag gttgcagata ttgaaccggg gcggctctgc cagatgggaa tagctaagca
     4981 ggtcattaat aaggctgcgc atgcgctctg aagatgagat gaccttgttc atgtactgca
     5041 gggcttccgg atcgccgccc aggaaccgtt ctattaccag gcggctgaag gtaatgatct
     5101 tgcgcagggg ctcctgcagg tcgtgggagg ctatgaaggc atactgctgc agctctgcat
     5161 tgctaagctc cagctcttta ttggcctgca ccagggcttt ggtacgctct tccaccttct
     5221 gctccagcgt ttctttaata tcattcagct cttttgtttg ccggtacagg cgggtaaagg
     5281 tttttacctt tagcagcaga atgtcggcat caaagggttt ggtaatataa tccactccgc
     5341 cggaggcata tcctttggtt acaaaacgtt tatcaatatt tactgcggac aggaaaatga
     5401 tgggaatgtc cttagagcgg ctgtaaccgg taatggtttc tgctacttca tagccgtcca
     5461 taccgggcat ttgcacatcg aggataatga gctcatattc attcctgagt atccttttca
     5521 gggcttcttc gccggaggtg gcagtgtcta cctcatacag attgaggcgg agcaaagctt
     5581 ttaacgagta aagattttcc tgtttgtcgt caacgatcaa gatcatactg gatgactgaa
     5641 atacattaat aaaaccagct tcagcaaatt acgcaggcgg gtacggtctg gcgcagggtt
     5701 ttgagggccg cgtgcaggtc aagatgcaca ttacctgcaa tggcttccag tatctcctgc
     5761 agctctttga ggctggtggg cttggtaata aagctcaccg cgcccttctg catggcctgt
     5821 tctacatcct ttggctgtga ggaggtggtg tacatgatca ccggtatctg tttaagggta
     5881 tcgtcctctt taagggctgc caggcactgg cggccatcca tacggggcat gttcaggtcc
     5941 aggaaaataa catccggccg ggtagtacct tcccgtaatg cggccagcgc ttcgtgccca
     6001 ttggcggcgg aagcgaacac cactgcgggg tctacctgct gcaatacttc ttcaaataat
     6061 gacgtgtcat ctaaatcatc atcaaccagc aaaaatgtag ttggattctt catataatcg
     6121 atctatagtt cgcgcaaaat taactcaatc tgaggagtat cagtgttttc ccataacagt
     6181 cccctccgcg taatgcggca tttttggacg tgtgtccctc cccgtgttgt ggtgtacggc
     6241 ggatcttaca attgaataga ggtataaacg aatattaaat ataaaaacat tttactgcat
     6301 ccggctattt tgcctggaat ttttgtttcc attcccgcag gcgctggggg taggcggtat
     6361 cctttttctc tgcaaagatc tttacccgtc cttttacggc tatgccggca taaataatat
     6421 cgcggttcat atctataacc agggcggctt cgtccatacc gcagttatgt ggctggcagc
     6481 cttcgttata gaagatgttg ccttctattt ctatgggcgg ggctacctgg aagcgctgga
     6541 agaacagcag gctatcccgg ttcagcaggc ggtgaaaacg ttctttcagc ggctctttat
     6601 ccagcaggtc cacctcgccg gcatagcggc cgatataatc ctcaaaacgg ctccaggagg
     6661 tgatctcatc ggccataatg gtatccggta cgggtatcat ggtgtcggcg gagggtatca
     6721 tagtggtatc cggccggcgt tgttccggtt ttttgggtat aacaggcttg catgcacaca
     6781 gctgtatgca aaacagtgaa ggcaacagca ttctcatagt tatggtagcg attctcatta
     6841 attcaattac aatttttggg tgctgccggg gttcaggtgt gtgttgcttt taccaatagt
     6901 tattatttac ctgtaaagcg cggcgcccgt ttttctataa acgcctgcat accttctttc
     6961 tgatcgtctg atgcgaacag caggtaaaaa ttcttacgtt caaagtgcaa cccttcctcc
     7021 aggctgctgt caaatgcttt gagcactgct tccttggcca ttttagtggc cagggggctc
     7081 ataccggcta tttcttttgc cagttttata gcttcttcca ggtatagctc tacaggcgtt
     7141 atacggttaa ccaacccggc ctgcagggct tctgcggcgg tgataaaacg tcctgtaagc
     7201 accatttcca tggccagggc tttacctacg gccctggtaa ggcgctgggt gccccctgcg
     7261 ccgggcatta cgcctagctt aatctccggc tgtccgaaac gggcggtttc actggctacg
     7321 atcatatcgc acagcatggc cagctcgcac cccccaccca gtgcaaaacc gcttacggct
     7381 gctatgatgg gtttctttgt ttttttgatg gcgtcccagg tgctgaactg atcggtgtta
     7441 tacatgtcta tggcgctttt acctgccatt tgtgtaatat cggccccggc tgcaaatgct
     7501 ttttcattgc cactgatgat gattgcgcga acctggtcgt cggcgtccag tgtttgcagg
     7561 gctgttttca gctctgtcat cagttgcagg ttcagcgcat tgagtgcatt gggacggttc
     7621 agctgtatgt gtgcaacgtg ggttgctacc tgttggtgta cgattataaa ttccggttgc
     7681 atctataaaa ttacagaatt accgcaaata tgatcaggat aaagaatacg cctacaaaag
     7741 caaagctgat accatacccg aataagagca gcaacgattt cccgaacgac cgcataaagc
     7801 tttgatgata ggtattccgt agcgccagca ccaggtaccc gaatataagc catacgctcc
     7861 agcctatgaa gccgtccaca cccgtgagct tttccaggat ataggccagc agcagtaccg
     7921 tgtacgcaaa gcagtgcaca tgcagggcaa aaatggcatg atccgtataa taccagcgct
     7981 tccagttgta aatgagcttt aaccaaaggg caaataaggg cagcagcaca aacatcattt
     8041 tagggaaatg gtgcttgagg gattctgaga ggttttcctg caggcggtca tctcccgggt
     8101 tcaaacgcat ccacttatgg gtaaagtacc gtttaagcca gccgtccctt tgtgcttttg
     8161 gcatggctgc ctgcgcggaa tcgtaggctt cctcattccc atatttattg cgcggatcgt
     8221 cctcactgtc ggttaatctc aggtcgtcgt cttcctcagc ttttgcggcg gtatgcctgg
     8281 cggcggccgt atcatggctg ccggcagcta ccggcgccac ggcgttatga ctcctggcgg
     8341 aatcgtaccg gtagcggtat gccagggaat ccactgcccg ggcaagttcc ttattatttt
     8401 tgagcgaatc ctttacggcg cccaggatcc cggtaatgga gggtatcttt tgactttcat
     8461 cttcctcatg ctgctttgca gctgcttcct tttcggcgga gcgtttttcg ttcttttcat
     8521 gggaatcatg ggaaagcatg gcccaggtga ggaaaaacac aaaggataca aaaatgtaca
     8581 gcttaatggg gtttacaaag gctacccggc ggccggccat gtattctttg gttaaacgcc
     8641 ccggcctgaa taacaggtaa ctgatcgttt gcagaaactg ggaatcataa tgcagcacat
     8701 cgcctacaaa atgttttacc aggtgaccaa aagattcatg gggaacggca ttttcctggc
     8761 cgcagtgcgt acaatacctt tccggaactt ccgttccgca attcaggcag tgtttatcct
     8821 cccgtaatgg ttgtgttttc aagtaattgc taggttaggc gcctcaaaat agcaaatctt
     8881 taccgcaaat ttccaaagga cagaaaatct tatatatcta aaaaattttc aaatgatttc
     8941 aacgttagta tttttgtcac cgattagcat ttacgcgttc aaactatgat gcacattaaa
     9001 aagtactgtt tattagcggg ttgcctgctg ctgttcactg cccgtagcat ggcccaatat
     9061 tattaccagg atatttacaa tacgcgccag accagcagta atatggcgca gctgaaggaa
     9121 aacaacgtaa gggtacagga ggtacaaagc ctggatgcca gtatggaaac cgacaatgat
     9181 ttcaggtgcc agcgcatcct ttcgcccaat ttccggcaaa tgcgggccat tacgcagtcg
     9241 cggggtacgg gactgagtat tatgacctct accttctctg ccaaaggcac gcttatgaaa
     9301 accacggaca gtacggagag cagcattact accatccagt acaaatacga tacggcgggg
     9361 cggcttacgg acattcatac cagctccctt tcagaggcgg gcagcagcaa gttccgtgtt
     9421 acagaaaccc gtacttacct gtatgatgaa aagggccacc tggccagcat gatccataaa
     9481 aagagcctgg gcggcaatga ctctaccacc gtgctgttta aaacggatga acaagggcat
     9541 gtaatagagg agcaggaata tggcaagaac atgcgcagcc cgcgcattta ttataactat
     9601 gatgcacagg gccggttaac ggatgtgctg cggtaccata ccggtaaaaa acgcatgctg
     9661 ccggattata tgtttgagta tgatgcgcag caacgccttt cacaaatgac cactgtaaat
     9721 gctgaaacgg ctgattacac tgtttggaaa tataagtatg atgaaaaagg attgccgctg
     9781 cgggaagagt gttatggtaa agagaaagcg ctgctgggca ttgtgaaata taattacgag
     9841 ttccttaaat aaacatctta tctagcgcca tagcgggtaa cagggcttta tgatattttt
     9901 atgacataac accgttcctt gttaacggta atcaatgtat atttagagat atgcttatgt
     9961 caatgtagtg acccattttt aaagccctgt tatttgctgt atggaaactc cgttcacttt
    10021 ttgtgacaac ctggtcataa gggttccgcg tttgcctttt caaccacatt ttgaagcagc
    10081 tacagtacag caattgctta cagatgccgc cttcctggaa tcagtgtaca ttgcctcacc
    10141 ggttttatat gatgaggcag tgcgtttacg cgaagggcag ctgcatacgg caaaagaaca
    10201 ggctaaggtt acggatgcgc tggttaaata ttatacccgc tcctacagcc gctgcactcc
    10261 ttttggatta ttttcttctt gcactacttt accctgggcg caaacaccct cccctgctga
    10321 ctttaaagcc atgcccctgc aaaggcgcac acggctggat atgtattacc tgggtgcatt
    10381 agcccaggag ctgctgcagc tgccctccat acgggaacgg ctattgtttt ttccgaacaa
    10441 cagccggtat gtaatgggga acgagctgcg gtacatggaa tacgagtatg tggaaaacaa
    10501 acggttttac cgcattagcg cagtggagca ccagccagct ttgcagacgg tgctggctgc
    10561 tgcagaaaaa ggggctacgc tgtttgagct atgtgcttta ttaacggttc ccgggcctga
    10621 tgcgctggac tatattaatt cccttgtaac tgcacaggta ctggtaagcg agctggaacc
    10681 agccattacc ggccctgctt ttttaacaca gctgctaact gtgctgcagc ggttacaggc
    10741 gcctgccgca cccgtattgg agcaggtgca ggctgccctg caagcgctgg atgcgcagga
    10801 taccaacccc attgctgctt acgaacatat tatacaactg atcacacagc tgcaaatacc
    10861 ttttgaagcg ggcaagctgc tgcaggtaga tgcattccgc ccggcagctg ccggcggtgg
    10921 tgtgcctgcc agcttacagg cggatctgtc aggcgcgctg gacattttac ataccctgca
    10981 ccaatataaa ggaggtaata tacctgcctt acaaaccttt attgaaaaat tttatgcgcg
    11041 gtatgcggat gaagccattc cgctggtaca ggcgctggat gcggaatccg gcataggcta
    11101 cccggccggg acggctgcgt catttgcacc gctggtagac gggctgccca taccggcaca
    11161 aacggacacg cctgcacgta ccttaacggc tacagatgaa tggctgctgg cacagctaac
    11221 gcgctgcctg cataccgggc agcaggagct ggtgctggac gatgctgtta ttccgcgcag
    11281 cgcagatcat acggagacct tccctccttc cctttctgcc gtgttccgac tgctggatgc
    11341 agctagcggc cacctgcagc tggaaggctt ttttggcccc agcgcagcag gtatgttagg
    11401 ccgctttgcc tatggcgata gccagctaca tgacctgaca ctgcatatta cgcaggaaga
    11461 acaacggctg aatgaagggg tgatctttgc agagatcatt cacctgccgg ataaccggac
    11521 aggcaacgtg atcctgcacc cggctttcag ggaatatgag atcccttacc tggcacaatc
    11581 ctccctgcct gcggagcggc aaatacctat acaggacctg tacctgcgcg tggtggacca
    11641 gcagctgcag ctattttcca aaaagctgga taaacaaatt ataccgcggt taagcaacat
    11701 gcataactat gcgctgcatg cattacccat ctattacttt ttatgcgacc tgcaaaagca
    11761 aggtttgcac actgcttatt tgtttgagtg gaagacccag cctttccgct ttactttttt
    11821 gccgcgggta cggtataaga atattgtatt aagcgtggcg caatggcagc tggaacaggc
    11881 agacatcagc gatttgcagc aaagcaccat ggaggccctg ccggccgccg tgcagcgctt
    11941 ccgggagcag tggcagctac cgcagctgct ggtgctggca gacggagatc atgagctgct
    12001 gatagacctg gataatttat atacggtaca ggcctggtta cgcacggtga aacaacggac
    12061 cacgtttact cttaaagaat ttttacctgg taccggcgac tatgtacagc aatgcgtggc
    12121 gcccatgatc aaaaccacgg ctacgtataa ccctgtacgt gagccggtgg aaactattat
    12181 tacaccgggc atacaacgca gctttcccgt gggatcggaa tggctgtatt ataagctgta
    12241 ttgcgggcct tcgctggcgg acaatatact tacagaacag gtacggcctg taatagaaac
    12301 attaacggca gccggtatta tagaccagtg gttctttatc cgctacctgg accctgactt
    12361 tcacctgcgt atacgctttc acttaacgga cagcaggctg gcaggggaag caattgccct
    12421 gctaagccag gccctggcgc ctttgcaggc atcgcacatg atctggaaaa cacgcctgga
    12481 tacttataaa cgggagctgg aaagatacgg cggcgctgct gccatggcac tgtctgaaaa
    12541 gctgttcttt tacgacagcc agaccaccct ggaactgtta gccatgctga gtggcgatga
    12601 gcaggaaaaa ataaaatggt tatgggcact gaaaggcatg gatacctggc tgaatgatct
    12661 tcagctggat gctacggaga agagagcctt cattctgcag cagaagacag cctttgcaca
    12721 ggaaatgcag gtggataaac ccatgcggca gcggctgaac cagcagtatg agcagcatgc
    12781 cgcctacatc catgaaatta tggaagctat taccccgcag aaccgttttt acccggtgct
    12841 gcagctgctg gaagcacgca gccaacaggt tgcgcccctt gcgcagcagc tcattcagct
    12901 acggcaacag gggcggctta atgttaactg gttccattta acgggcagct atgtgcacat
    12961 gatgataaac cggatcatga ccagtaaacc gcggcaatat gaaatggcgc tatatgatat
    13021 cctggaccgg tatgaagcac ggaagtatta tttggccaat atacaaaagg ggtagccgaa
    13081 acacctttaa aagagtaggc atttattgtt cacctaaaaa atctaaacca tgagtgtaaa
    13141 gtctcagcaa accaagtttt ccctggacgt gttagccaac tgggataaac aaagccacga
    13201 aaaactggct atgcacaaaa gaaccattgc taatgtaagc gaaactgctg taacaggacg
    13261 taaaggcaaa cagacggatt ctatcctgca ccagcctact actactgtta tcagcacctc
    13321 tcactaagca tttgtaacga gcagtaagta aaaacattta gtattcacct gaaaaaatct
    13381 aaaccatgag tgtaaagtct cagcaaacga agttttccct ggatgtatta gccaactggg
    13441 ataaacagag ccatgaaaaa ctggctatgc acaaacgcac cattgccaat gtgactgaaa
    13501 atgttgtaac aggccgtaag gaccgccagg cgcaagcact tcatacgtcg ccgaccacta
    13561 cggtgatcag cacttcgcac taatatttgt atcgagcagt aaatataaag gccgttccgg
    13621 gatggaacgg cctttgtttt atgaggatgg aaggatgtgc tggtttggat ggaggatgtg
    13681 agaatatacc gatgtgtaaa tgggaggatg tgttggtttg ggtgggagat gctggaatga
    13741 acagatgtgc aatggaagga tgggctggtt tgggtgaggg agatgctgga tatacggatg
    13801 tgtaatggaa ggatggcctg gtttgggtga ggaatgctgg aatgtacaga tgtgcaaatg
    13861 gaaggatggg ctggtttggg tgaggatgcg ggaatatacg gatgtgcaaa tgagaggatg
    13921 tgcgggtttg gtggagatgt aaaaaagggt gtaccaatat gatacaccct tctggaatta
    13981 tatgaatgta aatgtttatt actgtttcac cagcttgaca gtgcttacct taccgttgtg
    14041 caccagcttc agcacgtaca aaccaccggg catattaccg ggtgcaaatg tgcgggtatg
    14101 gcggccagcg ggcaattgct cattggccag cacctttact acctcgccat tcgtattata
    14161 tactgccagg tgcaccgggc ctgcctgctg cagggtaaat gctacggtag cattgctgct
    14221 taaggggttc gggaacacgc ttacctgctg cagcttatcg ccatgcgtat ctgaaggcga
    14281 cgctacaaat gcctgcctgg cggctgtttt agcggtgctg gtagtggtga tcaccagctg
    14341 cggggcatta ctgccggttt ctttggagtt ccaaagtgtg cgcgggttgg ccattaaacc
    14401 attcagcaat gccagggaaa tggccgaacg gccggctgcc ttttcacttt gtacatacgc
    14461 cgtaatatcc cagctgtagt aacggccaat agaatccgtt accgtggcgg tggccagcgc
    14521 agtggcgcct ggtgcgggct tgttgttcca ggtaatgccg gcttctgtcc aggtagtgtt
    14581 ggctaccggg tacgccccta cgggaacatt ggttacgcgg ttatcgtcct ggtggccgta
    14641 cactttcaat acggcggatg tgatagtgcc gcttacactg ctgagatcaa atcccaggta
    14701 agcctggcgg tcgttacctg ttgttgtggt ggagttcagc ttagagatca ggttcaccgg
    14761 gtccagtgca ccgtaggcgc tatcagcata aacaccatta cgtacatagg catcttttgc
    14821 agcgcttaat gttacctgct ggccgctctg cgtacctgtt ctcaccttta cttccgtgta
    14881 gctgttccag gcgcttacat tattgccatg gcctaagatg cgtacatact tagcggtttt
    14941 tgcagcaaac gtaaaacttt ccaatgccag cgaggtaccg ctgctttgca ggccggtagc
    15001 ggcattggta aacgtaagac catctgtgct ggtttgcaca tcaaacagcg cacggcgggt
    15061 attaccctgg taaaaagcaa tatccacccc ggttactgaa acaggattat ctaaacaaag
    15121 ctggatccat tgcccatccc cactggcaga ccagcgggta ttgaggtcat tatccagcac
    15181 attggtggcc acatttccat catcgctgct ggcgctggca ggaacacatg ccggcggcgg
    15241 tgtagtgcct gcttccggct tccaccagtt accggaaata aacagctggc ataacaggct
    15301 gtaagaatca ctgtaataac cggacttttt agttttcagg aagttccagc cactgttcac
    15361 aaaagcctgg ttagcgctgt tggccactgc ggctgccaca aaaggcgcta caaatactgc
    15421 ttcaggatca gtaccgctgg tggtaccatt cagctggtag ccatcgcgga tgctggccgg
    15481 gttgccgccg cttttctgga tgatccaggt ggctatttta ttggaaattg tttgcgcgct
    15541 tgtggagccg tataatgcat aatccattac cacgcgcagg ggtacacgac aagcgttgta
    15601 gttatattca ttggtttgcg gtccttcatc aataaagttc ttgggagcag gctccggcgg
    15661 attctttacc acgaagtcgg agattaaacc ggtggagggt gaataagtgg cgctgaactg
    15721 gttgtacacg ctgtacagat tattgatcag attcaaccag gcggcgtcat ttgtttcctg
    15781 gtaaaaggcg cgcatatggc ttaacatcca gtcggaaggg cgggtattca gcgcactttt
    15841 gctgtcccag tcgcccaggt tcaggcggtt agtggtggtc acattggcgg ctttaatacc
    15901 attggtgatc attttcttag cttcattcag gtaattgata gcgccatctg atccccactg
    15961 gtagtgcgcc agaatgaggg agtaggcgat atcaatatca ccatctgttg cggaatcgaa
    16021 atgcccttgt gcgctggcat tatctgctac tacccagccc ataatattgc tgttgataga
    16081 gctgcggtat gcccgcgctg ttttaaacag tccgtcgtaa atagtgcggg cattggcatc
    16141 atgaccggcc atcagcacag taataaccat gccatagcct tgtccttcag aggagcctaa
    16201 cggcgtatag ccgtccgcgt caccgctgat ctctccttta atgtaataac cgccgggcaa
    16261 tgaagccagg ttgttcttca ggtactttga tttccagtaa tcataaaagc ttgctacact
    16321 ggtgttcatg tcggcctgtg taacgttgtt tggtttgata cagccaggat agcttacagc
    16381 ttgtggaaat ggcttttttt gtgcttgtac gatcaggcct gcgatgcata gcatgccggt
    16441 tgccagtatg gcatagggtt ttctcataga cattgatttt aagggtgatt caggtttttc
    16501 tttataggtt ttcgttactg ctttgacgtg gttacaatgg taaaggtagg ggataaaatt
    16561 gtgaaatcat ttaccggatg aatgtatgag acttcgtagg tataaccgcc cgatgctttt
    16621 tcgatctggt gtgttttgtc tggtgtttga gaaggcgttc tttcccgtag gtccggctcc
    16681 ggcctgcacc cgcctgttta gttctttatt gggcgtaggg aggtcgtagc ggcattgggg
    16741 gatgacgggg cggtatcaag cggggcacgc cgggcaaagg gccgtcacct ggacctacgg
    16801 gtgcaaacga tgaagacctt tttggtaatg ccctttttga tgatggttta tgttgatgac
    16861 cttatggatg atatcctttt tgaacgtacg ggaggcaaac gatgagggtc tttttgatgg
    16921 tggcgtttga tgtttgatgt acctgtcctg atttaccttt atacctgctg gttttgcctg
    16981 cagatagccg ggagcttcaa tgtttcttaa acatttttag cgcttattaa tgcgcatctt
    17041 tctttattac tctttatcac cctctaccaa cttccattag ctttcattag cctttattag
    17101 cctctattat cccttactac tttattatct attatccttt gctactcctt aatgctctaa
    17161 tattctgcaa aggcatcatc tttatagcac caaagccatc tttcgcccgg ttctgcggag
    17221 gagataacgg ggtggccggt ttcgtgctgg tgatggctca tgtgctggct gggggaatcg
    17281 tcgcagcaga gcgtgacgcc gcaggtttgg caggtgcgca ggtgtaccca ttggccgcca
    17341 tgttttacgc attcagcgca ttcatatttt tctgcggttt ttatttcttc tatgctttgc
    17401 aggtgcttac agagttcggg ctgtgacatg ggcgttaatt gatgaatgat atttgatgta
    17461 taatgtataa tgtaagacga acaaagtata aagtataaag ccggctacta cttgttgttt
    17521 gccatttcat actttatact tcgttcagcc tattaattac taattcttta cttcacctct
    17581 gccagatact tatgtacaaa actaatggcc atggagccct ctcctacggc ggcggctaca
    17641 cggttcatgg cgctggcgcg aacgtcgccg gcggcaaaga tgccaggaca gctggtttcc
    17701 agcagataag gatcgcgctg ctgcttccag atcttgccga aagcgtcata ctttttcagc
    17761 tcacggccgg tttcaataaa tcccttgtca tccttgatga tgttgagagc tatccagtcg
    17821 gtgaagggct tggcgcctat gaaaatgtac agtgcgtcgg cggcttctgt gcaggtttcg
    17881 ccggtttcca cgttctttat taccagcttt tccagcttgt cggtgccaat ggcctctgca
    17941 atttctgtac gcgggcggat cttaatattg ctggcgcctt tgatctgctc tatcagatat
    18001 gcggacatcg tgctgctcag atcatcctta cggatcagga tgtacacgtt cttcgcaaac
    18061 ttcgataagt acatggcagc ctgcccggcg gagttgccgc cgcctacaat gtatacttcc
    18121 ttatccttgc aggccgtggc ttctgtcatg gcggcgccgt agtaaatgcc tgcgccggtg
    18181 aactgatcca ctccctgggt gtccagcttg cggtaatcta ccccggtggt aatgatcacg
    18241 ctgcgggtgt tgatcacgct atcatcttcc aggatgatct tattataacc atccttttgc
    18301 tgaatatctt ttacagattg cggtgtaata aactccgtac ccaaacgggt ggcctgcgct
    18361 atggcccggc gggtaagctc tgccccgctt aaaccggtgg gaaaacccag gtagttctcg
    18421 atacgggagc tggtacctgc ctgtccgccc ggtgcgcggc gttctatcag cagggtcttt
    18481 aatccttctg atgcaccgta tacaccggct gccagccctg cggggcctgc gccaatgatc
    18541 accacatcat atacatcatg ttttacgtgc gggttcagcc ctaccttacc ggcaatttcc
    18601 ataatggtag gcgttaccag gtagctaccg tcttcaaaga ataccacggg cagctctttc
    18661 aggcttaagt tgttcagctc cagcaggcgg tttgcatcgc tggtggtttg cacatccagc
    18721 cactggtaag gtatgaggtt gcctgccagg aaatccttta cggcatgtga ttgctgggag
    18781 aactggtagc ccactacttt aatgcctttg aaaaccggat ggtaaatgtg ctgccagtca
    18841 tccagcagct catcgatcac cgggtatagc ttttcttccg gcggacccca aggttttacc
    18901 aggtaataat ccagctgtac ggagttaatc gctttaatgg cggcatctgt atcagaataa
    18961 gcggtgagca gcacccggcg ggcttccggg tagaattgca tggccttttc caggaaatct
    19021 accccttcca ttacgggcat gcgctggtct gagatgaaca tggcaatggt ttcgcccttg
    19081 ttcttcagct ccagcaggct gtccagcgct tcattcactg tggtggtgct gataatttta
    19141 taattcttac ggtattgact tttgaggtcg cgtacaatag cacgcaatac ctgctcatca
    19201 tcatctatac agaaaattaa aggttgttcc atggcttttt ttagacggta tgtgttgaca
    19261 taatttccgc ggcgttaaat atacaattta aaagaatgat tacccttgta tgggcagcga
    19321 caccttaaac tccgttcttc cgggttctga gattaccttt acgttaccgt tatgctggcg
    19381 gacgatctgc ataacaatat ccaggcccat accggtgccc ttgccaatgc ctttggtggt
    19441 gaagaaggga tcaaaaacgc ggcttctgat ctcttccggg ataccggggc cattgtcgat
    19501 gatggacacg tatacgcagt ggcggtcctt cgaggtttgt atttccagca cacctttttt
    19561 attgggctcc atggcatcca gggcattgtc aatgaggttg gtccatacct ggttcatttc
    19621 gccaataagg gctttgatct gcggaagcgt attatcaaaa ttctccacca gctccacatt
    19681 gcccttacgc aggcggtgct gcagtatgac cagggtatta cggatgccgc tgtgaatgtc
    19741 tgtcagctcc ttatcatgcc cctggtccat gtgggtgaac acctttacgg atcctaccag
    19801 ggtggcaata cgtttggagg cttcttcgat atccagcacc attctttctt tcaccaggtt
    19861 actgttgatc cagttaaata cgggcgaaag gtccttttcc tgaatatgct gcttaaattc
    19921 ctccaggttc tcaagcgtaa aaccaaactc caccatgttc tctgccactt cctgactgtt
    19981 ggctacattg tgatcatcca gccagtccag cagctcatct tccttatctg aacgctgcat
    20041 gagggtaagc accggttttt ctgttccatg cagaatggag aatagtagct tgctcaccat
    20101 atctacctgc tccggcgttg ccttgatagc catgatctcc cggaaggtgg tgggttccag
    20161 ctgcagatgt tttttcaatg attccgcacc ccgtacaatt gcggcagcgg ggttattaag
    20221 ctcatgcgcc aggccggcgg agagcttgcc cagggccatc attttttcgt tctgctgctg
    20281 gaaggaggtg aattcccgca cacggtccgt catcatatgc accagggcct gtgtaagctc
    20341 aaaatgggtg cggatcagct ccggtgattt ctcgatggga aggctcatga tctgaacatc
    20401 ttccagggct tcgccaaaag cggcagccac cttgcctctt gaaaaaggta agtaaccggc
    20461 tatggaccgg gccggccata ttgccagctc ccgcgcttca ttattctgca gtcggtatac
    20521 gcgaatgcgg ccggttacaa taaaatgggt agcccagatg gccgtttccg gctcaaacag
    20581 gaatcctccc ggagggataa tataatgctg gctgttatcg atcatccatt gcagctgttc
    20641 tgccggaaca tccttaatgg cctctatggt ccggagccat tctacagtaa cctggttcat
    20701 cttaaattat tggtttagaa gtgggaaggc atgccgcagg gagatcatcc gtgcttgcaa
    20761 acttaaagtt acttaaattt gccctgtttt aggaaggatc agataagtac aaagttttaa
    20821 ggaatcatga gcaaggatgc aatcaggttg gatatttcca ctacggtcaa acattattta
    20881 gcggctgata acaatgcccc gcaaggcttc gggattgaaa aatacacgga cctgcaggcg
    20941 ggcgattttg cgatactaag caatgaaggc ggccggcata acggcccacc ggtgaaaacc
    21001 gatcattttg ccctggtgct gtgcatgcgc gggcacggcg ttaaaaccat cgggcaccat
    21061 acgtttgagg taacgccaca atccatacac atcgtctctc cccgcgacct gcactctttt
    21121 gaaaatgctt ctgacgatct gctgctatac atgatcctgt tcaggcatga gtttgtggcc
    21181 catactttta tcaaagaaca gatcctggat cagctgttag agctgccgcc ggagctccct
    21241 cccatttacc acctggatga acgtgagttc acctctatcc gcgatctttt catcaaaatt
    21301 gaacgggaat accgggaggc gcctgcctat tttttgcaga tggtgcggct gctggtagta
    21361 gagctattat atgaaattaa ccgcgcgcat gaaagggccc tgcagcaacc cactaaaccg
    21421 gcaggccggc ctttacagct ggtagccgcg tttaagaaac tggtggaagc gcacttttta
    21481 accatccgta ccgtacagca gtatgccgac ctgctgcatg tatctgccaa gcacctgagc
    21541 gagcaggtga aacatgctac cggcgaaaat gccctgacga tcattcacca gcggatattc
    21601 cgggaggcgg agtatttatt acatacctcc gatttcagta tcaaggaaat tgcggatcag
    21661 ttgaactttg acaccagctc gcactttagc cggttcttta agcattttgc gggggtgaac
    21721 ccttcagagt tcatggtgaa aaaggatacc gggaacaggc gtatcagcaa taaatgatag
    21781 ccgggacatg aaccacacct gaagaggacc agaagggaga acgcttttac ccatggggtt
    21841 accccggaat tttctaggga tgcacacggg aagtaagcca gtaccggatt atgaccggcg
    21901 aaggcattac cctgttaaag gcctgcgaga gcggtgtctg agatacagtc gcggttgatg
    21961 acggtgtacc tgaccggcag ttaggctctt tccggaaaat tggttctatt atcctcctta
    22021 ttggcattgt gcagtcttcc aagccgtcct aattttgtcc tatcaaacga tcaactaata
    22081 cacgtttcgt aagtattaaa accaatagaa gatgaaaaag acaatcaaga caggcattat
    22141 gggactgctc cttttaacag gtttaaccct ttcttccaaa gcacaggatg cctccaaaaa
    22201 agtaactgct gaaagacctg cttttctttt aagtgtaggc cccgaagcta atttaccctt
    22261 aggtgatttt aaagatgctt atgactggtc tatcggtggt tctgtacagg gcgattatgc
    22321 cattctgaaa agggacctgt acgttacgct gaatgccggt ttttctgatt ttatggccaa
    22381 agacattgcc ggtttttctg ccaaagacct gcagttaatt ccggtaaaag cgggtttgaa
    22441 atattacccg gtaagtaact tttatgtaca ggcacaggcg ggcgctgttt tcatagccaa
    22501 taagagcgat gtgctggctg ataaatctgc agcttttgct tactctccgc aagtgggcta
    22561 cctgttccat ttaggcaatg gcagctacct ggatgcaggt gtgaagtttg aaggttacag
    22621 caaatttgct gacggcggtt cttccaataa tgtattagga ctgcgtgtgg cttatgcctt
    22681 cggtttataa gtatttcata ggggttttaa aaaataggtt aaggaaaaag aaatgccccc
    22741 ggtgcttgcc tccgggggtg ttttttttgg gtgggatgaa tgacttttat ctataggatc
    22801 tttcagtgga atttagccac cggtaagggc ttttgactgg caggcaggac agattttgca
    22861 gcttttaaat tttccgaata gaaaaacttg gtgaattcca aagaatagct atctttgcaa
    22921 tcccaagaaa aaatagctct taaaaaatta tgcggaagta gctcatttgg tagagcacga
    22981 ccttgccaag gtcggggtgg ccggttcgag cccggtcttc cgctcagaga tagggttcca
    23041 aattgcgcaa gcggtttgga atttttattt acaat
//
