LOCUS       NZ_FNPT01000012        22820 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Lysobacter sp. yr284, whole genome shotgun sequence.
ACCESSION   NZ_FNPT01000012
VERSION     NZ_FNPT01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lysobacter sp. yr284
  ORGANISM  Lysobacter sp. yr284
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Lysobacter.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900107375.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 20:31:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,139
            CDSs (total)                      :: 5,059
            Genes (coding)                    :: 5,007
            CDSs (with protein)               :: 5,007
            Genes (RNA)                       :: 80
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 4 of 52
            Pseudo Genes (incomplete)         :: 50 of 52
            Pseudo Genes (internal stop)      :: 1 of 52
            Pseudo Genes (multiple problems)  :: 3 of 52
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:51:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 25953
            Orig. end                         :: 48773
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNPT01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22820
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22820
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22820
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12820](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12820)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(138..152)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            208..1764
                     /locus_tag="BLV01_RS16805"
                     /old_locus_tag="SAMN04487939_11225"
     CDS             208..1764
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (14-417). E-value: 2.6e-103.
                     Score: 337.7. Matches aSDomain:
                     nrpspksdomains_BLV01_RS16805_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017462359.1"
                     /locus_tag="BLV01_RS16805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11225"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_091802239.1"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-110, bitscore:
                     362.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGDRADFGSLSHALERSAAATPERIAVESGGERIGYGEFAAAAR
                     RCAGGLGELGVRRGDRVAVALPNGIAAAVALYGALRAGAAIVPLNPGIKGDKLAAILED
                     CQAKVLIGTAALAAQLPSARAQPLIVAADGAAPAAHASLDELMRAPERGAQVLEVDLAA
                     VIYTSGSTGVPKGVVLSHRNMAFASASICAYLGMHGDDRILSTLPLSFDYGLYQLLLCA
                     HVGASLLLEPGMGYPGELVRMLHERGVTGLPGVPTLFRVLLSLPGLDKRDWPQLRLITN
                     TGAALSGDTIQSLRRIFPQARLYSMYGLTECKRVSYLPPEELDRRPDSVGIAIPGTEVW
                     IEGERGERLRAGEVGELMVRGPHVMQGYWNAPAATAERLRAGRWPWERVLATGDLFRQD
                     AQGFLYFVGRRDDIIKSRGEKVSPREIENVLLAAPGVLDAAVLGVAHEVLGQAIWAHVS
                     PRPGAALDARELDRFCRERLEPHLVPARFAIHAQLPKSANGKIDKRALAQPLPQPEHDH
                     G"
     aSDomain        250..1458
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLV01_RS16805_AMP-binding.1"
                     /evalue="2.60E-103"
                     /label="BLV01_RS16805_AMP-binding.1"
                     /locus_tag="BLV01_RS16805"
                     /protein_end="417"
                     /protein_start="14"
                     /score="337.7"
                     /specificity="substrate consensus: Asp"
                     /tool="antismash"
                     /translation="LERSAAATPERIAVESGGERIGYGEFAAAARRCAGGLGELGVRRG
                     DRVAVALPNGIAAAVALYGALRAGAAIVPLNPGIKGDKLAAILEDCQAKVLIGTAALAA
                     QLPSARAQPLIVAADGAAPAAHASLDELMRAPERGAQVLEVDLAAVIYTSGSTGVPKGV
                     VLSHRNMAFASASICAYLGMHGDDRILSTLPLSFDYGLYQLLLCAHVGASLLLEPGMGY
                     PGELVRMLHERGVTGLPGVPTLFRVLLSLPGLDKRDWPQLRLITNTGAALSGDTIQSLR
                     RIFPQARLYSMYGLTECKRVSYLPPEELDRRPDSVGIAIPGTEVWIEGERGERLRAGEV
                     GELMVRGPHVMQGYWNAPAATAERLRAGRWPWERVLATGDLFRQDAQGFLYFVGRRDDI
                     IKSR"
     CDS_motif       691..750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV01_RS16805_0001"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BLV01_RS16805"
                     /protein_end="181"
                     /protein_start="161"
                     /score="29.9"
                     /tool="antismash"
                     /translation="AAVIYTSGSTGVPKGVVLSH"
     CDS_motif       1219..1341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV01_RS16805_0002"
                     /evalue="7.50E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="BLV01_RS16805"
                     /protein_end="378"
                     /protein_start="337"
                     /score="34.3"
                     /tool="antismash"
                     /translation="EVWIEGERGERLRAGEVGELMVRGPHVMQGYWNAPAATAER"
     CDS_motif       1423..1488
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV01_RS16805_0003"
                     /evalue="3.50E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="BLV01_RS16805"
                     /protein_end="427"
                     /protein_start="405"
                     /score="19.6"
                     /tool="antismash"
                     /translation="FVGRRDDIIKSRGEKVSPREIE"
     gene            1757..2947
                     /locus_tag="BLV01_RS16810"
                     /old_locus_tag="SAMN04487939_11226"
     CDS             1757..2947
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024844.4"
                     /locus_tag="BLV01_RS16810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11226"
                     /product="MaoC family dehydratase N-terminal
                     domain-containing protein"
                     /protein_id="WP_091802242.1"
                     /transl_table=11
                     /translation="MGEVSFESETLQRKAGEMPWLAQRSRRLLGGAALDVPAGVAVADW
                     LAISRYVAATGDDNPLYLDPVYGAGSWWRTQLAPPGFVLSIAVPESVGALYEESVDAVE
                     CLDRVELWWNDHIRLGDRVGARSHIVEAGPGEDADADAGVEVVTEADYRSEGRRIARAR
                     GRVRIRPLRLGSQRLVERDMHRYTPEQVERIEAGLAAEPAPRGGLPRFHGELAVGEALP
                     PTVRGPMTWSELQSWMVAEGRPAPAGNLRHRELLAQPGNIRAHAATDWAVCDRRQARED
                     LSACADVGFPAPSIRGSMAVALATQQVTAWMGDAAFLRQICVSLPAPVLYGDTLFLGGR
                     VADKYVQRIDGREFFAAALELHARNQLDETVMRATAIVFLPERGRPLQLPIEAEMF"
     gene            2951..4297
                     /locus_tag="BLV01_RS16815"
                     /old_locus_tag="SAMN04487939_11227"
     CDS             2951..4297
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024844.4"
                     /locus_tag="BLV01_RS16815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11227"
                     /product="MaoC family dehydratase N-terminal
                     domain-containing protein"
                     /protein_id="WP_091802244.1"
                     /transl_table=11
                     /translation="MAIAFQFDTVIDEFLARSRELIGLESREDRPPRIGPAAANEPMPG
                     ERIRSLFTLDEDSIRRYARTIGDDNPLFTDPQYGRASIHGSQIAPGPILVHCRYPADHG
                     ASREHGYPLANFIGNVAWEFYDVVRPGTAVSTSKVLREVLEPRGARGGRILLLVCEVVY
                     SDEFGKALAKAYGTLVQVPMKSMGESRAMPLESVDDSQLYERRPHRYQAGETEAILAGM
                     QDEARRGAEPRYWEDVAVGEVLAPIVQPPYALPDALSYQSLHQGLVAGYGGGVLGRSFA
                     PAYRAIKAGWGYPDFSRLHPVTQWPHTPGDEHEDAWLCGFRGQPLPFDFGIQRGQIPQR
                     LIGNWAGDSGFCRKLSMAMGRPLFHGDALTVRGRVIAKRIDREGESGQRYHCAVVAMDA
                     ANQRGETVSRGYASVYLPSRGEGAPALPIPLARTPPYVPYDRHRSQEWF"
     misc_feature    4316..4331
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.33"
                     /tool="antismash"
     gene            4318..5505
                     /locus_tag="BLV01_RS16820"
                     /old_locus_tag="SAMN04487939_11228"
     CDS             4318..5505
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016242.4"
                     /locus_tag="BLV01_RS16820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11228"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_175486038.1"
                     /transl_table=11
                     /translation="MQLETITDPARLEPERWDRLAHPSLYLSSDWLRARSRTVKAAGRL
                     ALLSDRDGPLAAAACYLSDENAHPGYFPPRLLGIDCLDEAALGSPAQAQALAQFHAQLK
                     QGAADWSPSLVVAAPGRYGGASFRAGLDAQAAARARAQLVEAIEDRAQRDAARSLCWLY
                     LIEGEDPLLEAALAERGYGRLILDAECYMPLPWDDFDGYLDSFRAEYRGTVKHEMAAFD
                     AAGVQVELRGADALDAELAALERQWRLKYGRTPELEEIVADYDELRAHLSDRLRVFVAV
                     QDGRAIGFSVFLDDGETWYSRFGGFSYDEGNLFLYFNLLFYRPLQAMIERGVRVARYSL
                     KSYEAKRSRGCLLRHVLAFVKPPPDWPSMRPVLDLLDHAQAERFAQISRRRISKR"
     gene            5567..6337
                     /locus_tag="BLV01_RS16825"
                     /old_locus_tag="SAMN04487939_11229"
     CDS             5567..6337
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016908.4"
                     /locus_tag="BLV01_RS16825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11229"
                     /product="FkbM family methyltransferase"
                     /protein_id="WP_175486040.1"
                     /transl_table=11
                     /translation="MSTPQPTAHVPLPNGLTLYLQSAHMRAAAEYVVDEIFVEKQYQRE
                     GFEIGHADTVVDIGANMGVFALWASPQAPAGRVISVEPVQEMMDCLRSNLDANRIRNVS
                     AVQAAVGPSGQKIELTYYPGFNIISHRSDFRRPAYARLKMYLKNWRVWRAPERVRAACI
                     SVGELLDEHGVDRVDLLKIDCEGGEYEIVRGMSERDWSRIDRIVMEFHEYHKDQRHEQL
                     VELLRNRGFEVEVEKDAMTYRLMRFGTLWARRAH"
     gene            6434..7870
                     /locus_tag="BLV01_RS16830"
                     /old_locus_tag="SAMN04487939_11230"
     CDS             6434..7870
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014160279.1"
                     /locus_tag="BLV01_RS16830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11230"
                     /product="MFS transporter"
                     /protein_id="WP_091802253.1"
                     /transl_table=11
                     /translation="MRPDAPADKRHPLLPLVLSCALFIENMDSSALATSLPAIAADLGT
                     DAISLKLALTAYLLAVAMFMPVSGWIADRIGARRAFLAAVGLFLLGSAACALSASAQAL
                     VAARFLQGTGGALMVPVGRLVLLRAVPKSELVRAMSWLTIPALIGPMIGPPLGGFITTY
                     FDWRGIFLINIPIGLLGIALAKRVIPDVREPPPPLDRLGLALTAPGLAAAMFGFASLGQ
                     RAVPVAASVAALAVGAGLLAGYAVHAARHPHPLLELRLLRIETYRAGVVGGSLFRVGVG
                     ATVLLVPLMLQLGFGLDPLQTGLLVFVSSIGAMSMKLVVTPLLRRFGFRRALLGNVLVA
                     SALVCGFGLFRAQTPHLWLAAALFAVGCSRSLQFTSLNAISFAEVDARAMASATSLAGT
                     MVQLSLSLGVVVGAHALELSAAATGRPVADPLGFRIAFAVVAAISLASAWSLWRLRDDA
                     GSELSGHVRAGAHDDAGAKP"
     gene            8079..8588
                     /locus_tag="BLV01_RS25605"
     CDS             8079..8588
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV01_RS25605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_139178803.1"
                     /transl_table=11
                     /translation="MRIHLENCEETHNSDATPIACERTSREISGIDTFDRLHRVAHRAL
                     HRQPEAPKPEAGRTAGCPFRSCGRVPQAAHSPPGERDSSDITSWSKQFMYRTKMKLMAA
                     AVFAMGLAIGGIASAQAPVPGQSCSPNGRSVNDVKNGWRYYYRCTGGKWILEKVCPVGG
                     GICYSP"
     misc_feature    8662..8678
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.77"
                     /tool="antismash"
     gene            8912..9991
                     /locus_tag="BLV01_RS16840"
                     /old_locus_tag="SAMN04487939_11232"
     CDS             8912..9991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015879511.1"
                     /locus_tag="BLV01_RS16840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11232"
                     /product="DUF4105 domain-containing protein"
                     /protein_id="WP_091802259.1"
                     /transl_table=11
                     /translation="MPAAKIPPVPGAGRGWLRIAALGLLSTAILAVAAWGAGLIAFQGP
                     AAAPLRNGLIGAWCLLGAAACAALPWRRASAARRAAPIAFAAGFAVLLAWWFALAPSQD
                     RDWADDVARQFDAQVRGDRVVLRNVRDFQWRSETDYTPRWETREYDLSKLSSADLVLSY
                     WMGPNIAHTLVSFGFDDGRRLVFSLEIRKERGESFSALGGFFRRFEQVLVAADERDIVR
                     TRSNARGEDVYLYRLNLPPQTLRPMFLGFLAKADELKRKPAFYNTLTSNCTTVVFEIAR
                     HVVPDLPLDYRLLAAGHFAEYVYDQGGLVPGYSYAQLRERGYVNPRARAIPADAADAGA
                     YSRAIRRGVPGIAASELAR"
     gene            complement(10001..12820)
                     /locus_tag="BLV01_RS16845"
                     /old_locus_tag="SAMN04487939_11233"
     CDS             complement(10001..12820)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="BLV01_RS16845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11233"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_175486042.1"
                     /sec_met_domain="DUF4135 (E-value: 8.5e-72, bitscore:
                     235.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.1e-35, bitscore:
                     114.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAGSVGGFAPIVEHFCAAARDRLAASLAQLAPALDPEEIRLIR
                     DAAVEALHANARLKLNRVLLLELYAAKCADELGGGDDAARFERFVQRCRQDDFGRHLDR
                     RYPNLRARLARVLYEQCAGTTALAARLARDRAALAPLLGGDAGRLSAIALGLGDLHAHG
                     QAVARLSFEGGQVMYKPRSLRVDAALDRFLQRLFPADPHRIRVPAVVDRGDYGWAEHVA
                     HRYCDGDGELRRFYAGLGQWLAVLRLLGGTDIHLENLIAVGPTPVVVDVESLFAHTHAT
                     APSGYGHAHDLARELIRSSVLRTGIVPSRAPTLGFDNVDLSAAGALPGEQPRVLAPVIA
                     GEGTTDAHVEIISVEVGLAQNHPSPQPELSRYWDGISSAFLDTSERLRRLDADGALAPL
                     IGEFVGCSVRDIRRTTKAYLEIGRMLWHPASLHDEAKAVARARDLFVRNAAVMPAAPSS
                     AEEIDREIDDLRHADIPVFASSLTPQRVDAALAGWRAMRIDLEEMTIRSALVVTELNHR
                     ANAPMDDSQRRYHARRPHADDLERRRRTLAAQAVERLLSLAVYGDDRSATWITPGASGA
                     GWHVHPLQSDIYSGLGGVAVALAGYRREVGHGRADPVAGTDEAIDGALRVLARMAAGER
                     LESAGGFSGYGSRIWSWLLLHDLLERPELLEHALAYAGRLEAEGFDADRSLDLIDGCSG
                     AIVPLLGLARRSGDPRWLELAARAGRHLESMAIVDERGARWPAAAFAEPVGGFAHGAVG
                     IAWSLTRLALAGAGSPGDRQRWSALAEAGFAFQDGLFDASSGNWREAISGKADIHTWCG
                     GSVGIGLAAADLYARTAAPRHLRDLRRAVAASQGYWGLSHTLCHGDFSLWALLARASAL
                     DPDGSASDCADATAQVVSALEEHHGMVGGMTREAFTPGLMTGLAGAVHGLAGMHPHARP
                     QSPLLLECG"
     gene            complement(12920..13201)
                     /locus_tag="BLV01_RS16850"
                     /old_locus_tag="SAMN04487939_11234"
     CDS             complement(12920..13201)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040361.3"
                     /locus_tag="BLV01_RS16850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11234"
                     /product="DUF6229 family protein"
                     /protein_id="WP_139178805.1"
                     /transl_table=11
                     /translation="MPGKDALCVLDSLRSQGFFRHHNRRSGDMQNDDHVSDWLNGADSV
                     DGRGNPAGPLYIEGAAATEDALTSPNEANMFSTRTAITCSGVACCICA"
     CDS             13217..13378
                     /gene="allorf_039170_039331"
                     /locus_tag="allorf_039170_039331"
                     /protein_id="allorf_039170_039331"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSIAASVVRMRTCGPVRENAASASSRRSKAFVHIWCGATMKLTVP
                     RRTFGDEL"
     CDS_motif       13217..13291
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSIAASVVRMRTCGPVRENAASASS"
                     /locus_tag="allorf_039170_039331_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13292..13378
                     /prepeptide="core"
                     /locus_tag="allorf_039170_039331_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="3204.8"
                     /monoisotopic_mass="3202.7"
                     /core_sequence="RRSKAFVHIWCGATMKLTVPRRTFGDEL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSIAASVVRMRTCGPVRENAASASS"
                     /leader_location="[13216:13291](+)"
                     /alternative_weights="3222.8"
                     /alternative_weights="3240.8"
                     /alternative_weights="3258.8"
     misc_feature    13309..13325
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.87"
                     /tool="antismash"
     CDS             13490..13651
                     /gene="allorf_039443_039604"
                     /locus_tag="allorf_039443_039604"
                     /protein_id="allorf_039443_039604"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPTRSPAPESKAPMAAAQSLFRGARSQRDHDLWQASRRAIGAHSP
                     GVGRCAEP"
     CDS_motif       13490..13540
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPTRSPAPESKAPMAAA"
                     /locus_tag="allorf_039443_039604_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13541..13651
                     /prepeptide="core"
                     /locus_tag="allorf_039443_039604_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="3902.3"
                     /monoisotopic_mass="3900.0"
                     /core_sequence="QSLFRGARSQRDHDLWQASRRAIGAHSPGVGRCAEP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPTRSPAPESKAPMAAA"
                     /leader_location="[13489:13540](+)"
                     /alternative_weights="3920.3"
                     /alternative_weights="3938.3"
                     /alternative_weights="3956.3"
     gene            13690..14475
                     /gene="lepB"
                     /locus_tag="BLV01_RS16855"
                     /old_locus_tag="SAMN04487939_11235"
     CDS             13690..14475
                     /EC_number="3.4.21.89"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lepB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014161131.1"
                     /locus_tag="BLV01_RS16855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11235"
                     /product="signal peptidase I"
                     /protein_id="WP_091802521.1"
                     /transl_table=11
                     /translation="MRWFEIALVSLTAFTGLVWLLDKHWLARRRAAHAGLLDEGDEPWV
                     VDYSKAFFPVLLVVLLLRSFVAEPFRIPSNSMMPTLLTGDFVLTNKFVYGLRLPISNTK
                     VLPMGEPARGDVVVFHSVQRADVNLIKRVVGLPGDRVEYRDGRLTINGAAVAYTPIGAY
                     TGHGSGAEATGAQELSETLGRHVHRVLLRRDLPQPLLAEGEWTVPAGQYFVMGDNRDNS
                     EDSRYWGFLPERNLVGRAFLVWLNFDDGFDFERIGTSIP"
     gene            14583..15542
                     /locus_tag="BLV01_RS16860"
                     /old_locus_tag="SAMN04487939_11236"
     CDS             14583..15542
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660347.1"
                     /locus_tag="BLV01_RS16860"
                     /note="predicted Zn-dependent protease with a strongly
                     conserved HExxH motif; predicted Zn-dependent protease with
                     a strongly conserved HExxH motif; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SAMN04487939_11236"
                     /product="DUF2268 domain-containing putative Zn-dependent
                     protease"
                     /protein_id="WP_139178807.1"
                     /transl_table=11
                     /translation="MPKPSLAPPAPDRRRRLRAAVCLALLAIAAAANAAGPAGEPDIRT
                     DDVDRFYALYAATDGKPSVAQLDEYLAQGSPSLKEFAQLRRVSGERIAAQMAADPAMYR
                     DARECMKLLPQVKRRVAASLRTLGELYPQARFPPVAIVVGRGKPVGITNPAGVTVGLEA
                     LCAADFMNPDPEDRFVRVIAHEYAHIQQPAAAQDLAPDDPRASVLGMSLTEGGAEFVAE
                     LIAGGVANPGLAVRVRGRERAIGEAFLREQDDRDFSGWMFNYRKGSDEPYDQGYWVGYR
                     IARAYYQRAGDKRAALARILEMPDTKAFLRDSGWAPGQ"
     CDS             15576..15722
                     /gene="allorf_041529_041675"
                     /locus_tag="allorf_041529_041675"
                     /protein_id="allorf_041529_041675"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGAATAAESIGSEGPATALLCRICPHPAFARADRAALRTGPETGV
                     KHR"
     CDS_motif       15576..15611
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGAATAAESIGS"
                     /locus_tag="allorf_041529_041675_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15612..15722
                     /prepeptide="core"
                     /locus_tag="allorf_041529_041675_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="3786.3"
                     /monoisotopic_mass="3784.0"
                     /core_sequence="EGPATALLCRICPHPAFARADRAALRTGPETGVKHR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGAATAAESIGS"
                     /leader_location="[15575:15611](+)"
                     /alternative_weights="3804.4"
     misc_feature    complement(15645..15660)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     misc_feature    complement(15708..15723)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.76"
                     /tool="antismash"
     gene            15820..18201
                     /locus_tag="BLV01_RS16865"
                     /old_locus_tag="SAMN04487939_11237"
     CDS             15820..18201
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1107:
                     TonB-dependent receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017157997.1"
                     /locus_tag="BLV01_RS16865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11237"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_091802268.1"
                     /transl_table=11
                     /translation="MSVVSAARLPQRSRVATDHSRRPLARTALASAVASLLLLGAALPA
                     AAQQAAEADAAPARATEGNATQLDAITVTAERREQNLQDVPVSVGVVQGDAMRVFTAGG
                     DDTLLALSGKVPSFYAETTTGRIFPRFYIRGLGNIDFYLGASQPVSIIQDDVVLEHVVL
                     KSNPVFDVDQVEVLRGPQGSLFGRNTTAGIVKFDSIKPSQDYSGRLSASYGTYNTVSLD
                     GGVGGPINDVLSFRVSALYQHRDDWVDNTYNGPSADGTVSPKKDTMGGYDDRNLRVQFL
                     LQPSENFSLLASAHARDYDGTSTLFLRNALRKGSNEVFGARDKVAYDEAGDNPQAYKTY
                     GGSVKATWRFNEMSLTSISAYETTSGYSRGDTDGGAAANYPVNGQPNGYGQSMGQVRDL
                     DQLTQEIRLASENDDALQWQLGAFYFDGRDTTDFYQRAWFLSGNARNPNNWVRLRNSNT
                     SWAAFGQLSYKFGDKFTVTAGVRETRDSKRTRLLKTADSAAGVSTYKGRRDVEMADTTP
                     SWDLSAMYEINPQVSVYGRVARGFRGPTIQGRSAVFNADFTTAESETILSWEAGVKSSL
                     FDNRLRLNAAAFTYTVDDIQLNGNDSNGNGVLFNADKARAYGVEADLDWRPIPNLSITA
                     GASWLHSEIQDKRVYAQVCGLNGQVVCTVNDPTIKIGSNVFAQVDGNPLPNAPKYNLSL
                     GARYDIPVSDAGAFFVATDWNKQGYTSFVLYDSKEFNSRGNFEGGLSVGYTGGYGAYEV
                     ALFARNITNEKNLKGVIENYMAAVYNEPRVVGVSLNLKWP"
     gene            18386..19540
                     /locus_tag="BLV01_RS16870"
                     /old_locus_tag="SAMN04487939_11238"
     CDS             18386..19540
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012376.4"
                     /locus_tag="BLV01_RS16870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11238"
                     /product="metallophosphoesterase"
                     /protein_id="WP_175486044.1"
                     /transl_table=11
                     /translation="MDASVPAARRRRLGLALYAACLGSAVAAPPPAAPPAPAAEAAFDD
                     GPYIRYAEGAVIARWVCAGKVLERRYPAARWPVRVPPRCGFERPILVRAPAQPQADAAD
                     APVARIAALSDVHGQYDLLVRLLQAHGIVGRDLRWRYGRGHLVVVGDVFDRGPKVNQAL
                     WLLYSLEQQARDAGGGVHYLIGNHEAMALGGDLRYVNPGYQRSAAALGETYPQLYGPDS
                     VLGQWLRTRQAIARVGGMLFVHGGISPDYLAGDVDTERSNAAYRASLGTPKAVWQDDPQ
                     LSPLYNGKTSPIWYRGYFTDPALQREQVDAIAARLGVSRIVVGHTTHHHIASYFDGRVI
                     GVDSGLKNGESGEILLVEDGEPTRGALDGGRLPLLPGERLKDED"
     gene            19732..20250
                     /locus_tag="BLV01_RS16875"
                     /old_locus_tag="SAMN04487939_11239"
     CDS             19732..20250
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV01_RS16875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487939_11239"
                     /product="hypothetical protein"
                     /protein_id="WP_091802273.1"
                     /transl_table=11
                     /translation="MNMRKSARAAAIAAMWGLALAAAALPAAAADWVHSGRYQYFSEGP
                     LGGNGSNGCQSGATPLPSGDCVADPGTGWAANFNAAMAAADAVEATGVCVLGYQYPSSC
                     RFAGYALNGQGVSASETFYAPNDLPRPCVAGTHAVGYVIFRRVVDAQDGSPDDRGIESD
                     YSADEYQCR"
     gene            complement(20346..20774)
                     /locus_tag="BLV01_RS16880"
                     /old_locus_tag="SAMN04487939_11240"
     CDS             complement(20346..20774)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007805921.1"
                     /locus_tag="BLV01_RS16880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_11240"
                     /product="OsmC family protein"
                     /protein_id="WP_091802276.1"
                     /transl_table=11
                     /translation="MTASTVPSVHARGESAPYAVSFVDDGEHRWQADEPAEVGGGDSAP
                     SPERLLLSSLGACTAITVRMYAERKQWPLAQVEVTLRFNPAGKPAAGTDIEREIVLRGE
                     LSEEQRERLLQIANACPIHKVLTGEVRIATALAAGAQA"
     misc_feature    21016..21032
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.97"
                     /tool="antismash"
     CDS             complement(21153..21236)
                     /gene="allorf_047106_047189"
                     /locus_tag="allorf_047106_047189"
                     /protein_id="allorf_047106_047189"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTVGEDAASPPAWFPRGPEPDSVEARC"
     CDS_motif       complement(21201..21236)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTVGEDAASPPA"
                     /locus_tag="allorf_047106_047189_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21153..21200)
                     /prepeptide="core"
                     /locus_tag="allorf_047106_047189_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="1727.9"
                     /monoisotopic_mass="1726.8"
                     /core_sequence="WFPRGPEPDSVEARC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTVGEDAASPPA"
                     /leader_location="[21200:21236](-)"
     gene            21495..21962
                     /locus_tag="BLV01_RS16885"
                     /old_locus_tag="SAMN04487939_11241"
     CDS             21495..21962
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV01_RS16885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487939_11241"
                     /product="hypothetical protein"
                     /protein_id="WP_091802279.1"
                     /transl_table=11
                     /translation="MFDRSHLIAHWRQAPPAPAGALDIVEFGPGDFSQPASGQAIGVVR
                     GERATFAEPLHFWIAAQRAGERFGARVDGAQAHPGETRYIEAALCQPIDRAVFARIVGE
                     YAAMLRAPLPAFVREPEGWRRGLRMYQQFNDVAALVETDRHYFVFAWTLSG"
     misc_feature    complement(22428..22442)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     misc_feature    complement(22631..22645)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 cggcgtacgt gcgcgagacc ttcctgccgc tgcgcccgga ccacccgctg gcgcaggacg
       61 acgacctgat cgagaccggc gtgctggatt cgctggcctt catcgagctg gtggcgcaga
      121 tcggacggcg ctaccgcatc gaggtcgccg ataccgacgt gaccggcgag aacttcggct
      181 ccatcgccgc gatagcgcgc tacgtcgatg accggcgacc gcgctgactt cggctcgctg
      241 agccacgcgc tggagcgcag cgccgccgcg acgccggagc gcatcgcggt ggagagcggc
      301 ggcgagcgca tcggctacgg cgaattcgcc gccgcggccc ggcgctgcgc gggcgggctg
      361 ggcgaactcg gcgtgcgccg cggcgaccgc gtggccgtcg ccctgcccaa cggcatcgcc
      421 gcggccgtgg ccctgtacgg cgcattgcgc gccggcgcgg cgatcgttcc gctcaatccc
      481 ggcatcaagg gcgacaagct cgcggcgatc ctcgaggact gccaggccaa ggtcctgatc
      541 ggcaccgcgg cgctggccgc gcagctgccg tcggcgcgcg cgcagccgct gatcgtcgcc
      601 gccgacggcg ccgcgcccgc ggcgcatgcc tcgctcgacg aactgatgcg ggcgcccgaa
      661 cgcggtgcgc aggtgctcga ggtcgacctg gccgcggtca tctatacctc cggctcgacc
      721 ggcgtgccca agggcgtggt gctgagccac cgcaacatgg cgttcgcgtc ggcctcgatc
      781 tgcgcctacc tgggcatgca tggcgacgac aggatcctgt cgaccctgcc gctgtcgttc
      841 gactacggcc tgtaccagct gctgctgtgc gcgcacgtcg gcgccagcct gctgctggag
      901 ccgggcatgg gctatcccgg cgaactggtg cgcatgctgc acgagcgcgg cgtcaccggg
      961 ctgccgggcg tgccgaccct gttccgggtg ctgttgtcgc tgccggggct ggacaagcgc
     1021 gactggccgc aactgcgctt gatcaccaac accggcgcgg cgctgtcggg cgataccatc
     1081 cagtcgctgc gcaggatctt cccgcaggcg cggctgtatt cgatgtacgg gctcaccgag
     1141 tgcaagcggg tcagctacct gccgccggag gagctggacc gccggcccga ctcggtcggc
     1201 atcgcgattc ccggcaccga ggtctggatc gaaggcgagc gcggcgagcg cctgcgcgcg
     1261 ggcgaggtcg gcgagctgat ggtgcgcggt ccgcacgtga tgcagggcta ttggaacgct
     1321 cccgcggcca ccgccgagcg cctgcgcgcc ggccgctggc cgtgggagcg ggtgctggcc
     1381 accggcgatc tgttccgcca ggacgcgcag ggcttcctgt acttcgtcgg ccgccgcgac
     1441 gacatcatca agtcgcgcgg cgaaaaggtc tcgccgcggg aaatcgagaa cgtgctgctg
     1501 gccgcgcccg gcgtgctgga tgcggcggtg ctcggcgtcg cccacgaagt cctcggccag
     1561 gcgatctggg cgcacgtgtc gccgaggccg ggcgcggcgc tggacgcgcg cgagctggac
     1621 cgtttctgcc gcgaacggct ggagccgcac ctggtgccgg cgcgcttcgc gatccacgcg
     1681 caactgccca agtcggcgaa cggcaagatc gacaagcgcg cgctcgccca gccccttcca
     1741 caaccggaac acgaccatgg gtgaggtttc gttcgaatcc gaaacgctgc agcgcaaggc
     1801 cggcgagatg ccgtggctgg cgcagcgcag ccggcgcctg ctcggcggcg ccgcgctgga
     1861 cgtccccgcc ggcgtcgccg tcgccgactg gctcgcgatc tcgcgctatg tggccgccac
     1921 cggcgacgac aatccgcttt acctcgaccc ggtctacggc gccgggtcgt ggtggcgcac
     1981 gcaactggct ccgcccggat tcgtgctgtc gatcgcggtg cccgagtcgg tcggcgcgtt
     2041 gtacgaggaa agcgtcgacg cggtggaatg cctggaccgg gtcgagctgt ggtggaacga
     2101 ccacatccgc ctcggcgacc gggtcggcgc gcgcagccat atcgtcgaag ccggtccggg
     2161 cgaggatgcc gacgccgatg ccggcgtcga ggtggtcacc gaggccgact atcgcagcga
     2221 aggccgccgg atcgcgcggg cgcgcgggcg cgtgcggatc cggccgttgc gactgggatc
     2281 gcagcggctg gtcgagcgcg acatgcaccg ctacacgccc gagcaggtcg aacgcatcga
     2341 ggccggccta gcggcggagc cggcgccgcg cggcggcttg ccgcggttcc atggcgaact
     2401 ggccgtgggc gaggcgttgc cgccgacggt gcgcgggccg atgacctggt cggaactgca
     2461 gagctggatg gtcgccgaag ggcggccggc gccggccggc aatctgcgcc atcgcgaact
     2521 gctcgcgcag ccgggcaata tccgcgccca tgccgccacc gactgggcgg tctgcgaccg
     2581 gcgccaggcg cgcgaagacc tgtcggcctg cgccgacgtc ggcttccccg cgcccagcat
     2641 ccgcggctcg atggcggtcg cgctggcgac ccagcaggtc accgcctgga tgggcgatgc
     2701 cgcgttcctg cggcagatct gcgtatcgct gccggcgccg gtgctgtacg gcgacacgct
     2761 gttcctcggc ggccgggtcg cggacaagta tgtgcagcgc atcgacgggc gcgagttctt
     2821 cgccgccgcg ctggaactgc acgcgcgcaa ccaactcgac gagacggtga tgcgggccac
     2881 cgccatcgtg ttcctgcccg aacgcgggcg cccgctgcag cttccgatcg aagcggagat
     2941 gttctgagcc atggccatcg ccttccagtt cgacaccgtc atcgacgaat tcctggcccg
     3001 cagccgcgag ttgatcggct tggagagccg cgaggaccgg ccgccgcgga tcgggcccgc
     3061 ggcggcgaac gagccgatgc cgggcgagcg catacgcagc ctgttcaccc tcgacgagga
     3121 cagcatccgc cgctacgcgc ggaccatcgg cgacgacaat cccttgttca ccgacccgca
     3181 gtacgggcgc gcctcgatcc acggcagcca gatcgcgccc gggccgatcc tggtccactg
     3241 ccgctatccc gccgaccacg gcgccagccg cgaacacggc tatccgctgg ccaacttcat
     3301 cggcaacgtc gcctgggagt tctacgacgt ggtccggccg ggcacggcgg tatcgacttc
     3361 caaggtcctg cgcgaagtgc tggaaccgcg cggcgcgcgc ggcggccgga tcctgctgct
     3421 ggtgtgcgag gtggtctaca gcgacgagtt cggaaaagca ctggccaagg cctacggcac
     3481 gctggtgcag gtgccgatga agagcatggg cgagagccgg gcgatgccgc tggaatccgt
     3541 cgacgacagc cagttgtacg agcgccggcc gcatcgttac caggccggcg aaaccgaggc
     3601 gatcctggcc gggatgcagg acgaggcgcg ccgcggcgcc gagccgcgct attgggagga
     3661 tgtcgccgtc ggcgaggtgc tggcgccgat cgtgcagccg ccgtatgcgc tgccggacgc
     3721 gctgagctac cagtcgctgc accaggggct ggtggcgggc tacggcggcg gcgtgctggg
     3781 gcgttcgttc gcgccggcct atcgggcgat caaggccggg tgggggtacc ccgatttttc
     3841 ccggctgcat ccggtcacgc agtggccgca cacgcccggc gacgagcatg aggacgcgtg
     3901 gctgtgcgga ttccgcggtc agccgctgcc cttcgatttc ggcatccagc gcggccagat
     3961 tccgcagcgt ctgatcggca actgggccgg cgacagcggc ttctgccgca agctgtcgat
     4021 ggcgatgggc cgcccgctgt tccacggcga cgcgttgacg gtgcgcggcc gggtgatcgc
     4081 caagaggatc gaccgcgagg gcgaatccgg tcagcgctat cactgcgcgg tggtcgcgat
     4141 ggacgccgcc aaccagcgcg gcgaaaccgt ctcgcgcggt tacgccagcg tgtacctacc
     4201 cagccgcggc gaaggcgcgc cggcgctgcc gatcccgctc gcgcgcacgc caccctatgt
     4261 tccgtatgat cgccaccgtt cgcaggaatg gttctgacga tgtccgccgg aggcgatatg
     4321 cagttggaaa cgatcaccga ccccgcacga ctggagccgg agcgctggga ccggctcgcg
     4381 catccctcgc tgtatctgtc cagcgattgg ctgcgcgcgc gcagccgcac ggtgaaggcg
     4441 gccgggcggc tggcgctgct gtcggaccgc gacggcccgc tggccgcggc cgcgtgctac
     4501 ctcagcgacg aaaacgccca cccgggctat ttcccgccgc gactgctggg catcgattgc
     4561 ctggacgagg cggcgctggg ttcgcccgca caggcgcagg cgctggcgca gttccacgcc
     4621 cagctcaagc aaggcgctgc ggactggagc ccgtcgctgg tggtcgccgc cccgggccgc
     4681 tacggcggcg ccagcttccg cgccggcctc gatgcgcagg cggcggcgcg cgcacgcgcg
     4741 cagttggtcg aggcgatcga ggaccgggcg cagcgcgacg cggcgcgatc gctgtgctgg
     4801 ctgtatctga tcgaaggcga agacccgctg ctggaagcgg ccctcgccga acgcggctat
     4861 ggccggctga tcctggatgc ggaatgctac atgccgttgc cgtgggacga cttcgacggc
     4921 tacctggaca gcttccgcgc cgagtaccgc ggcacggtca agcacgaaat ggccgcgttc
     4981 gacgccgccg gggtgcaggt ggaactgcgc ggcgccgatg cgctggacgc ggaactggcg
     5041 gcgctggagc ggcagtggcg gttgaagtac ggccgcaccc cggagctgga ggagatcgtc
     5101 gccgactacg acgaactgcg cgcgcacctg tccgaccggt tgcgggtgtt cgtggccgtg
     5161 caggacggcc gcgcgatcgg gttttcggtg ttcctcgacg acggcgagac ctggtactcg
     5221 cgcttcggcg gcttcagcta cgacgaaggc aacctgttct tgtacttcaa cctgctgttc
     5281 taccgtccgc ttcaggcgat gatcgagcgc ggcgtgcggg tcgcgcgtta ttcgctcaag
     5341 tcctacgagg ccaagcgcag ccgcggttgc ctgttgcgcc atgtgctggc cttcgtcaag
     5401 ccgcccccgg attggccgtc gatgcggccg gtcctggacc tgctcgacca cgcccaggcc
     5461 gagcgcttcg cgcagatatc ccgccgccgc atcagcaagc gctgagcccg gcggggcgcg
     5521 gccgcgtggg ccttccttcc accgcgagac caacggagcg agcaccatgt ccacgcccca
     5581 gccgaccgcc catgttccgc tgcccaacgg cttgaccctg tacctgcagt cggcgcacat
     5641 gcgcgcggca gccgagtacg tcgtcgacga gatcttcgtc gagaagcagt accagcgcga
     5701 gggattcgag atcggccatg ccgatacggt ggtggacatc ggcgccaaca tgggcgtgtt
     5761 cgcgctgtgg gcgtcgccgc aggcgccggc ggggcgcgtg atctcggtcg agccggtgca
     5821 ggaaatgatg gattgcctgc gcagcaacct cgacgccaac cgcatccgca acgtcagcgc
     5881 ggtacaggcg gcggtggggc cgtcggggca gaagatcgaa ctcacctatt atccgggctt
     5941 caacatcatc tcccatcgct ccgacttccg ccggccggcg tatgcgcgcc tgaagatgta
     6001 cttgaagaac tggcgggtct ggcgcgcgcc cgagcgggtc cgggccgcct gcatctcggt
     6061 cggcgaattg ctcgacgagc atggcgtgga ccgggtcgac ctgctcaaga tcgattgcga
     6121 gggcggcgag tacgagatcg tccgcggcat gagcgagcgc gactggagcc ggatcgaccg
     6181 catcgtcatg gagttccacg agtaccacaa ggaccagcgc cacgagcaac tggtcgaact
     6241 gttgcgcaac cgcggcttcg aggtcgaggt ggagaaggat gcgatgactt accggttgat
     6301 gcgcttcggc accctgtggg ccaggcgcgc gcattgaccg cgcgcgcgtc gccgggccgc
     6361 gcgcccggga cgcggccgcc gccgcggctg cggctgcggc gcgtcgccgc cgccgcgatg
     6421 cgggcgtgac cgcatgaggc cggacgcgcc cgcggacaag cgccatcccc tgctgccgct
     6481 ggtgctgtcg tgcgccttgt tcatcgagaa catggactcg tccgcgctcg cgacctcgct
     6541 gccggcgatc gccgcggacc tgggaaccga tgccatctcg ttgaagctgg cgttgaccgc
     6601 atacctgctc gcggtcgcca tgttcatgcc ggtcagcggc tggatcgccg atcgcatcgg
     6661 cgcgcggcgc gcgtttctgg ctgcggtcgg cctgttcctg ctgggttcgg cggcgtgcgc
     6721 gctcagcgcc agcgcccagg ctctggtcgc cgcgcgcttc ctgcagggaa ccggcggcgc
     6781 cttgatggtg ccggtggggc ggttggtgtt gctgcgtgcg gtccccaaga gcgagctggt
     6841 cagggcgatg agctggttga ccatccccgc gttgatcggg ccgatgatcg gaccgccgct
     6901 gggcggcttc atcaccacct atttcgactg gcgcgggatc ttcctgatca acattccgat
     6961 cggcctgctc ggcatcgccc tggcgaagcg ggtgattccc gacgtgcgcg agccgccgcc
     7021 gccgctggac cggctggggc tggcgctgac cgcgccgggg ctggcggcgg cgatgttcgg
     7081 tttcgccagc ctgggccagc gcgcggtgcc cgtcgcggcg tccgtggcgg cgctggcagt
     7141 cggcgccggc ttgctggccg ggtacgcggt gcatgcggcc aggcacccgc atcccttgct
     7201 ggaactgcgg ctgctgcgga tcgaaaccta ccgcgccggc gtggtgggcg gctccttgtt
     7261 ccgcgtcggc gtcggcgcga ccgtattgct ggtgccgctg atgctgcaat tggggttcgg
     7321 cctggatccg ttgcagaccg gcttgctggt gttcgtctct tcgatcgggg cgatgtcgat
     7381 gaagctggtg gtgacgccgc tgctgcgccg gttcggtttt cgcagggcgc tgctcggcaa
     7441 cgtactggtc gcatcggcgc tggtctgcgg cttcggcctg ttccgcgcgc aaaccccgca
     7501 tctgtggctg gcggcggcgt tgttcgcggt gggctgctcg cgttcgctgc agttcaccag
     7561 cctcaacgcg atcagcttcg ccgaggtgga tgcgcgcgcc atggcgtcgg cgacgagcct
     7621 ggccgggacc atggtccagc tgtcgctgag cctgggcgtg gtcgtcggcg cgcacgcgct
     7681 cgaactctcc gccgcggcga ccggccggcc ggtcgccgac ccgctggggt tccgcatcgc
     7741 cttcgccgtg gtcgcagcga tatcgctggc ttcggcgtgg tcgctttggc gcctgcgcga
     7801 cgacgcgggc agcgaactct ccggccatgt gcgggcgggc gcgcacgacg atgcgggcgc
     7861 caagccttag cctggatcgc tcaagtcggg gcgcttgtgc cggccggctc cacgggcggg
     7921 cgcctgggcg gatccgcggc gattcggtca tcggcgcggc aacgcatgcg caggcgaagc
     7981 cgccgcggat tgtgcggcgc gcgagaccga agcggaaatc tgcggcgttc attgcgttgc
     8041 gctgcagcgg cgagcgtctc ggccgctgcg cgacatcgat gcgcatccat ctggaaaact
     8101 gcgaggaaac acacaattca gatgcaacgc ccatcgcctg cgaacggaca tcgcgcgaaa
     8161 tatcgggtat cgatacattc gaccgattgc atcgggttgc gcatcgcgca ttgcatcgtc
     8221 agcccgaagc gccgaagccg gaggcgggca gaaccgctgg atgtccgttc cgatcgtgcg
     8281 gccgcgtgcc gcaggctgcg cattcgccgc caggcgagcg cgattccagc gacatcacgt
     8341 catggagtaa acagttcatg tatcgaacga agatgaagtt gatggccgcc gcggtgttcg
     8401 cgatgggcct ggcgatcggc ggcatcgcca gcgcgcaggc gcccgtgccc gggcagagct
     8461 gcagccccaa cggaaggtcg gtgaacgacg tcaagaacgg ttggcgctac tactaccggt
     8521 gcacgggcgg caagtggatc ctggaaaagg tctgccccgt cggcggcggc atctgctact
     8581 cgccgtaacc gctgcggccg gctgaggccg caacgcgcat ggacccagcg ccgccgatgc
     8641 gcggcgcacc cccggcaccg tcgcccatcg ccggtgcggc catgcgttct cgaaagcgtc
     8701 ccgcgtgcgc ggggcgcttt cgagcgacgg acgcgaggcc gcgcgtcgcg gccatctgtc
     8761 gggcctgggc gagggcaaca tcgcgcgcgt cgccgcgcaa gacatggccg gtcgaacggc
     8821 cgcgccaggg ggcgggcagg caaggcatgc cgcgcgccgg gccgccagcg taaagtagcg
     8881 gaccggattc gcccgtacgc aaggagtcgc catgcccgct gcaaagatcc cgccggttcc
     8941 cggcgcgggg cgagggtggc tgcgcatcgc cgcgctggga ctcttgtcga cggcgatcct
     9001 ggcggtcgcc gcctggggcg cgggcttgat cgcgttccag ggcccggccg cggcgccgct
     9061 gcgcaacggc ttgatcggcg cgtggtgcct gctcggcgcg gccgcctgcg cggcgttgcc
     9121 gtggcgacgc gcaagcgcgg cgcggcgggc ggcgccgatc gccttcgcgg ccggcttcgc
     9181 cgtattgctg gcgtggtggt tcgcgctggc gccctcgcag gaccgcgact gggccgacga
     9241 tgtcgcccgc cagttcgatg cgcaggtgcg cggcgaccgc gtggtgctgc gcaacgtgcg
     9301 cgatttccag tggcgcagcg agaccgacta caccccgcgc tgggagacgc gcgaatacga
     9361 cctgtcgaag ctgtccagcg ccgatctggt gctgtcgtac tggatgggcc cgaacatcgc
     9421 ccacacgctg gtgtcgttcg gcttcgacga cggccggcgg ctggtgttct cgctggagat
     9481 ccgcaaggag cgcggcgaaa gcttctccgc gctgggcggt ttcttccgcc gcttcgagca
     9541 ggtgctggtg gccgccgacg agcgcgacat cgtgcgcacc cgcagcaacg cccgcggcga
     9601 ggacgtctac ctgtatcgcc tgaaccttcc gccgcagacg ctgcggccga tgttcctcgg
     9661 ctttctcgcc aaggccgatg agttgaagcg caagccggcg ttctacaaca ccttgaccag
     9721 caactgcacc acggtggtgt tcgagatcgc ccgccacgtc gtcccggacc tgccgctgga
     9781 ctatcgcctg ctggcggccg ggcacttcgc cgaatacgtc tacgaccagg gcgggctggt
     9841 gccggggtac agctacgcgc agttgcgcga acgcggctac gtcaatccgc gcgcgcgcgc
     9901 gatcccggcc gacgccgcgg acgcgggcgc ctactcgcgc gcgatccggc gcggcgtgcc
     9961 gggcatcgcc gcgtccgaac tggcgcggtg agccggccgg tcagccgcac tccagcagca
    10021 gcggcgactg cggccgcgcg tgcgggtgca tgccggccag gccgtggacc gcgccggcca
    10081 gcccggtcat caggccgggg gtgaacgcct cgcgggtcat cccgccgacc atgccgtggt
    10141 gttcttccag cgccgagacg acctgcgcgg tcgcgtcggc gcagtcgctc gccgagccgt
    10201 ccggatcgag cgcggacgcg cgcgccaaca gcgcccacag cgaaaaatcg ccgtggcaca
    10261 aggtgtgcga aaggccccag tagccctgcg aagcggcgac ggcgcggcgc aggtcgcgca
    10321 gatggcgcgg cgcggcggtg cgcgcgtaca ggtcggccgc ggccaggccg atgccgacgc
    10381 tgccgccgca ccaggtgtgg atatcggcct tgccggagat cgcttcgcgc cagttgcccg
    10441 aggacgcgtc gaacaagccg tcctggaacg cgaatccggc ctcggccagc gcgctccagc
    10501 gctggcggtc cccggggctg ccggcgccgg cgagcgccag ccgcgtcagc gaccaggcga
    10561 tgccgaccgc gccatgggcg aagccgccga ccggttcggc gaacgccgcg gccggccagc
    10621 gcgcgccgcg ttcgtcgacg atggccatcg attccaggtg ccggcccgcg cgcgcggcca
    10681 gttccagcca gcgcggatcg ccgctgcgcc gggcgaggcc gagcagcggc acgatcgcgc
    10741 cgctgcagcc gtcgatgagg tcgagggagc ggtcggcgtc gaagccctcg gcttcgagcc
    10801 tgccggcgta ggcgagcgcg tgctccagca gttcggggcg ttccagcaag tcgtgcagca
    10861 gcagccagga ccagatccgg ctgccgtagc cgctgaagcc gccggcgctt tccaggcgct
    10921 cgcccgcggc catgcgggcg agcacgcgca gcgcgccgtc gatggcctcg tcggtgccgg
    10981 cgaccggatc ggcgcggccg tggccgacct cgcgccgata gccggccagc gcgaccgcga
    11041 cgccgccgag cccggagtag atgtccgatt gcagcgggtg cacgtgccag ccggcgccgc
    11101 tcgcgcccgg cgtgatccag gtcgcggagc ggtcatcgcc gtatacggcc aggctcagca
    11161 ggcgctcgac cgcctgcgcg gcgagcgtgc ggcggcgccg ttccaggtcg tcggcgtgcg
    11221 gccggcgcgc gtggtagcgc cgctgcgagt cgtccatcgg cgcgttggcg cggtggttca
    11281 attcggtcac caccagcgcg ctgcggatcg tcatttcttc caggtcgatg cgcatcgcgc
    11341 gccagccggc gagcgcggca tcgacccgct gcggcgtcag cgacgaggcg aacaccggaa
    11401 tgtcggcgtg gcgcagatcg tcgatttccc ggtcgatctc ctccgccgag gacggcgcag
    11461 ccggcatcac cgccgcgttg cgcacgaaca ggtcgcgggc gcgtgcgacc gccttggctt
    11521 cgtcgtgcag cgacgccggg tgccacagca tccggccgat ctcgagatag gccttggtgg
    11581 tgcggcggat gtcgcgaacg ctgcagccga cgaattcgcc gatcagcggc gccagcgcgc
    11641 cgtcggcgtc gagccggcgc aggcgctcgc tggtgtcgag gaaggcgctg ctgatgccgt
    11701 cccaatagcg cgacagttcc ggctgcgggc tgggatggtt ctgggccagg ccgacttcga
    11761 cgctgatgat ctcgacgtgg gcgtcggtgg tgccttcgcc cgcgatcacc ggcgcgagca
    11821 cgcgcggctg ctcgccgggc agggcgccgg cggcggacag gtcgacgttg tcgaaaccca
    11881 gcgtcggcgc gcgcgagggc acgatgccgg tgcgcagcac ggaactgcgg atcagctcgc
    11941 gcgccaggtc gtgggcgtgg ccgtatccgg acggcgcggt ggcgtgggtg tgcgcgaaca
    12001 ggctctcgac atcgaccacc accggcgtcg ggccgaccgc gatcaggttt tccaggtgga
    12061 tgtcggtgcc gccgagcagg cgcagcacgg ccagccattg gcccaggccg gcatagaagc
    12121 ggcgcagttc gccgtcgccg tcgcaatagc ggtgggcgac gtgctcggcc cagccgtagt
    12181 cgccgcgatc caccaccgcg ggcacgcgga tgcggtgcgg gtcggccggg aacaggcgct
    12241 ggagaaaccg gtcgagcgcc gcatccacgc gcagcgagcg cggcttgtac atgacctggc
    12301 cgccctcgaa cgagagccgc gccaccgcct ggccgtgcgc gtgcaggtcg cccaggccga
    12361 gcgcgatcgc gctcagccgc ccggcgtcgc cgccgagcag cggcgccagc gcagcgcggt
    12421 cgcgcgccag gcgcgcggcc agcgccgtcg tcccggcgca ttgctcgtag agcacccgcg
    12481 ccaggcgcgc gcgcaggttc ggatagcggc ggtcgaggtg gcggccgaag tcgtcctgcc
    12541 ggcagcgctg gacgaaccgt tcgaagcgcg cggcatcgtc gccgccgccg agttcgtcgg
    12601 cgcacttggc cgcgtacagc tccagcagca gcacgcggtt gagcttgagc cgcgcattgg
    12661 cgtgcagcgc ttcgaccgcg gcgtcgcgga tcagccggat ttcttcgggg tccagggccg
    12721 gcgcgagttg cgccagcgac gcggcgagcc ggtcgcgggc cgccgcgcag aaatgttcga
    12781 cgatcggcgc gaagccgccg acggagcctg catcggtcat cgtgtcgtcc atgagcggga
    12841 aggatcgggc cccgccgccg cgaaggcgcg gggcggcgcg cagcctaacg cggctgcgcg
    12901 ccgttgcttg cggcagaact caggcgcaga tgcagcaggc gacacccgag caggtgatcg
    12961 cggtgcgggt cgagaacata ttggcttcgt tcggggacgt cagcgcatct tcggtcgccg
    13021 cggcgccttc gatgtagagc gggccggcgg gattgccgcg gccgtcgacg ctgtcggcgc
    13081 cgttgagcca atcggacaca tggtcgtcgt tttgcatgtc gccactcctt cggttgtggt
    13141 gtcggaagaa gccctgcgaa cggaggctgt ccaacacaca cagcgcatcc ttgccgggca
    13201 tcggtctgca acttccttga gcatcgcggc gtccgtcgtg cggatgcgga cgtgtggtcc
    13261 ggtgcgggaa aacgccgcat ccgcatcgtc gcgcaggtcg aaagcgtttg tccatatttg
    13321 gtgcggcgcg acaatgaaac tgacagtgcc gcggcgaacg ttcggcgacg aactgtgatc
    13381 gtcgtgcgca tgggcgtact cgcagttcac aaacgtcgaa tcgcgcgcgc ggcactacgt
    13441 acgttcggtc gtatccgagc gagcgccgcg gtccgcgccg gcttcgcgct tgccgacacg
    13501 gtcgcccgca cccgaatcga aggcgccgat ggccgctgcg cagtcgcttt ttcgtggcgc
    13561 acgatcgcag cgcgaccatg acttgtggca ggcgtcgcgg cgcgcgatcg gcgcacactc
    13621 gccaggcgtc ggccgttgcg cggagccgta acgatggcgc gcccgggtcc gacctccatg
    13681 gagcaagcga tgcgctggtt cgaaatcgca ctggtgtcgc tcaccgcctt caccgggctg
    13741 gtgtggctgc tcgacaagca ctggctggcc aggcgccgcg ccgcgcacgc gggcctgctc
    13801 gacgaaggcg acgagccctg ggtggtggat tactccaagg cgttcttccc ggtgctgctg
    13861 gtggtgctgt tgctgcgcag cttcgtcgcc gagccgttcc ggattccgtc gaattcgatg
    13921 atgccgacgc tgctgaccgg cgatttcgtc ctgaccaaca aattcgtcta cggcctgcgc
    13981 ctgccgatca gcaacaccaa ggtgctgccg atgggcgagc ccgcgcgcgg cgacgtggtg
    14041 gtgttccact cggtgcagcg cgccgacgtc aacctgatca agcgcgtggt cggcttgccc
    14101 ggcgaccgcg tcgagtaccg cgacgggcgc ctgaccatca acggcgccgc ggtggcctac
    14161 acgccgatcg gcgcctacac cggccacggc agcggcgcgg aagcgaccgg cgcgcaggag
    14221 ctcagcgaaa ccctcggccg ccatgtccac cgcgtgctgc tgcgccgcga cctgccgcag
    14281 ccgttgctgg ccgaaggcga gtggacggtg ccggcggggc agtacttcgt catgggcgac
    14341 aaccgcgaca acagcgagga cagccgctac tggggcttcc tgcccgaacg caacctggtc
    14401 gggcgcgcgt tcctggtctg gctcaatttc gacgacggtt tcgacttcga acgcatcggc
    14461 acgtcgattc cctgaccgcg gcggcgcatg cgcaagtcat gacttgcggc agtgagcagg
    14521 cacggccagc gggcgcagac tcggcgctgt ccgcgcagcc gcgccaccga aatccgccgc
    14581 ccatgccgaa gccgtcgctc gccccgcccg cacctgaccg ccgtcgtcgc ctgcgcgccg
    14641 ccgtctgcct ggccctgctc gccatcgccg cggccgccaa cgcggccggg ccggccggcg
    14701 agccggacat ccgcaccgac gacgtcgacc gcttctacgc gctgtacgcc gccaccgacg
    14761 gcaagccgag cgtggcgcaa ctggacgaat acctcgccca gggcagcccc agcctcaagg
    14821 agttcgccca gctgcgaagg gtcagcggcg agcgcatcgc cgcgcagatg gcggccgatc
    14881 cggcgatgta ccgcgacgcg cgcgaatgca tgaagctgct gccgcaggtg aaacggcggg
    14941 tggcggcgtc gctgcgcacg ctcggcgagc tgtatccgca ggcgcggttt ccgccggtgg
    15001 cgatcgtggt cggccgcggc aagccggtcg gcatcaccaa cccggccggc gtgaccgtcg
    15061 ggctggaggc gctgtgcgcg gcggacttca tgaatccgga cccggaagac cgcttcgtgc
    15121 gggtgatcgc gcacgagtac gcgcacatcc agcagcccgc cgccgcccag gatctggcgc
    15181 ccgacgaccc gcgcgcgagc gtgctgggca tgtcgctgac cgagggcggg gcggagttcg
    15241 tcgccgaact gatcgccggc ggcgtcgcca atccgggcct ggccgtgcgc gtgcgcggcc
    15301 gcgagcgggc gatcggcgaa gcgttcctgc gcgagcagga cgaccgcgat ttcagcggct
    15361 ggatgttcaa ttaccgcaag ggctcggacg agccttacga ccagggctac tgggtcggtt
    15421 accgcatcgc ccgggcctac taccagcgcg ccggggacaa gcgcgcggcg ttggcccgga
    15481 tcctggaaat gccggatacc aaggcgttcc tgcgcgacag cggatgggcg ccggggcagt
    15541 gagcgcgggg cgcggcgtgg cggcggcgcg cgggcgtggg cgcggcgacc gcagcggaaa
    15601 gcatcgggtc tgaaggcccg gccacggcgc tgctttgccg tatctgtccg cacccggcgt
    15661 tcgcccgcgc cgatcgcgcc gcgctgcgca cagggcctga aactggcgtg aaacacaggt
    15721 gacatacctt gccgcggcgc ggagaatacc gcccccgctg ccggccccgc gccagccgga
    15781 cgcattcgca gccaggcgcc acgaaaggat cccaccccca tgtccgttgt ttccgccgca
    15841 cgcctgccgc agcgcagccg cgtcgccacc gaccattccc gtcgcccgct cgcgcgcacc
    15901 gcgctggcca gcgccgtcgc cagcctgctg ctgctcggcg ccgcgctgcc ggccgccgcg
    15961 cagcaggcgg cggaggccga cgccgcgccg gcgcgcgcca cggaaggcaa cgccacccag
    16021 ctcgacgcca tcaccgtcac cgccgagcgc cgcgagcaga acctgcagga cgtgccggtc
    16081 tcggtcggcg tggtccaggg cgatgccatg cgcgtgttca ccgccggcgg cgacgacacc
    16141 ctgctggcgc tgtcgggcaa ggtccccagc ttctacgccg agaccaccac cggccgcatc
    16201 ttcccgcgct tctacatccg cggcctgggc aacatcgact tctacctcgg tgcctcgcag
    16261 ccggtgtcga tcatccagga cgacgtcgtg ctcgaacacg tcgtgctcaa gtccaacccg
    16321 gtgttcgacg ttgaccaggt cgaagtgctg cgcggcccgc agggctcgct gttcggccgc
    16381 aataccaccg ccggcatcgt caagttcgac agcatcaagc cgagtcagga ctactccggc
    16441 cgcctgagcg ccagctacgg cacctacaac accgtctcgc tcgacggcgg cgtcggcggc
    16501 ccgatcaacg acgtgctgtc gttccgcgtg tcggccctgt accagcaccg cgacgactgg
    16561 gtcgacaaca cctacaacgg ccccagcgcc gacggtaccg tgtcgccgaa gaaggacacg
    16621 atgggcggct acgacgaccg caacctgcgc gtgcagttcc tgctgcagcc cagcgagaac
    16681 ttctcgctgc tggcctcggc ccacgcccgc gactacgacg gcacctcgac cctgttcctg
    16741 cgcaacgcgc tgcgcaaggg ttccaacgaa gtgttcggcg cgcgcgacaa ggtcgcctac
    16801 gacgaagccg gcgacaaccc gcaggcctac aagacctatg gcggttcggt gaaggccacc
    16861 tggcgcttca acgagatgtc gctgacctcg atcagcgcct acgagaccac ctccggctac
    16921 agccgcggcg acaccgacgg cggcgccgcg gcgaactatc cggtcaacgg ccagcccaac
    16981 ggctacggcc agtcgatggg ccaggtccgc gacctcgacc agctgaccca ggaaatccgc
    17041 ctggccagcg aaaacgacga cgccctgcag tggcagctcg gcgcgttcta cttcgacggc
    17101 cgcgacacca ccgacttcta ccagcgcgcc tggttcctca gcggcaacgc gcgcaatccc
    17161 aacaactggg tgcgcctgcg caacagcaac acctcctggg ccgcgttcgg ccagctgagc
    17221 tacaagttcg gcgacaagtt caccgtcacc gccggcgtgc gcgagacccg cgacagcaag
    17281 cgcacccgcc tgctcaagac cgccgacagc gcggccggcg tgtccaccta caagggccgc
    17341 cgcgacgtgg agatggccga caccacgccg agctgggacc tcagcgcgat gtacgagatc
    17401 aacccgcagg tcagcgtcta cggccgcgtc gcccgcggct tccgcggccc gaccatccag
    17461 ggccgctcgg cggtgttcaa cgccgacttc accaccgccg agtcggaaac catcctgtcg
    17521 tgggaagccg gcgtgaagtc gagcctgttc gacaaccgcc tgcgcctgaa cgcggcggcg
    17581 ttcacctaca ccgtcgacga catccagctc aacggcaacg actccaacgg caacggcgtg
    17641 ctgttcaacg ccgacaaggc ccgcgcctac ggcgtcgagg ccgacctgga ctggcgcccg
    17701 attccgaacc tgtcgatcac cgccggcgcc agctggctgc acagcgagat ccaggacaag
    17761 cgcgtctacg cccaggtctg cggcttgaac ggccaggtgg tgtgcacggt caacgatccg
    17821 accatcaaga tcggctcgaa cgtgttcgcc caggtcgacg gcaacccgct gccgaacgcg
    17881 cccaagtaca acctcagtct cggcgcgcgc tacgacatcc cggtcagcga cgccggcgcg
    17941 ttcttcgtcg ccaccgactg gaacaagcag ggctacacca gcttcgtgct gtacgactcc
    18001 aaggagttca actcgcgcgg caacttcgag ggcggcctga gcgtgggcta caccggcggt
    18061 tacggcgcct acgaagtggc gctgttcgcg cgcaacatca ccaacgagaa gaacctcaag
    18121 ggcgtgatcg agaactacat ggcggcggtg tacaacgagc cgcgcgtggt cggcgtgtcg
    18181 ctcaacctca agtggccgtg atcgcgcgcc tgggttgacc gcaacggccc ggccgcggcg
    18241 gggcttgcga aaaacggggc tcttcggagc cccgttttgc gttgcgcgcg gccaaggccg
    18301 cggcgcaacc gccaggaaac ggacttgtcc gcgggcccgc caggcgccaa gctcgggcgc
    18361 tgtccgtcgc cgcaccggag atcccttgga cgcatccgtt cccgccgccc gccgccggcg
    18421 cctgggcctg gcgctgtacg ccgcctgcct cggcagcgcg gtcgccgcgc cgccgccggc
    18481 cgcgccgccg gcgcccgccg ccgaagccgc cttcgacgac ggcccctaca tccgctacgc
    18541 cgagggcgcc gtgatcgcgc gctgggtctg cgccggcaag gtgctcgagc gccgctaccc
    18601 ggccgcgcgc tggccggtgc gggtgccgcc gcgctgcggt ttcgagcggc cgatcctggt
    18661 gcgcgcgccg gcgcagccgc aggccgatgc ggcggacgcg ccggtggcgc ggatcgcggc
    18721 gctgtcggac gtgcacggcc agtacgacct gctggtgcgg ctgctgcagg cccacggcat
    18781 cgtcggccgc gacctgcgct ggcgctacgg ccgcggccat ctggtcgtgg tcggcgacgt
    18841 cttcgaccgc ggccccaagg tcaaccaggc gctgtggttg ctgtactcgc tggaacagca
    18901 ggcgcgcgac gccggcggcg gcgtgcatta cctgatcggc aaccacgagg cgatggcgct
    18961 cggcggcgac ctgcgctacg tcaatcccgg ctaccagcgc agcgccgcgg cgctgggcga
    19021 gacctacccg cagctgtacg gccccgacag cgtgctcggg cagtggctgc gcacccgcca
    19081 ggccatcgca cgcgtcggcg gcatgctgtt cgtgcacggc ggcatctcgc ccgactacct
    19141 cgccggcgac gtcgacaccg aacgcagcaa cgccgcgtac cgcgcctcgc tcggcacgcc
    19201 caaggcggtg tggcaggacg atccgcagct gtcgccgctg tacaacggca agaccagccc
    19261 gatctggtac cgcggctatt tcaccgatcc ggcgctgcag cgcgaacagg tcgatgcgat
    19321 cgccgccagg ctcggcgtct cgcgcatcgt cgtcggccac accacccacc accacatcgc
    19381 cagctacttc gacggccggg tgatcggcgt ggacagcggc ctcaagaacg gcgagagcgg
    19441 cgagatcctg ctggtcgagg acggcgagcc cactcgcggc gcgctcgacg gcggccggct
    19501 gccgctgctg cccggcgagc ggctcaagga cgaagactga acgcggtcgc gcggccgccg
    19561 tgcatcgcgc gcgccgcgaa cgtgcgcggc gtcgggccgg cgcggcgaag ctgatcggaa
    19621 gatgagcgga cggcccgaaa ctgcaatctg ccgttcgcat gcctgcgtta ttctcgcgcc
    19681 gcttgcacag gcgacctctc gccgcgcatt catacgacag gagcggcaag gatgaacatg
    19741 cgcaagtcgg ctcgggccgc ggcgatcgcg gcgatgtggg gcctggcgct ggccgccgcg
    19801 gcgttgccgg cggccgcggc cgactgggtc cacagcggcc gctaccagta cttcagcgaa
    19861 ggcccgctcg gcggcaacgg ctccaacggt tgccagagcg gcgccacgcc gctgccctcg
    19921 ggcgactgcg tcgccgatcc cggcaccggc tgggccgcca acttcaacgc cgcgatggcc
    19981 gcggccgacg cggtcgaagc caccggcgtg tgcgtgctgg gctaccagta cccgtcctcg
    20041 tgccgcttcg ccggctacgc cctcaacggc cagggcgtgt cggcgagcga gaccttctac
    20101 gcccccaacg acttgccgcg tccctgcgtc gccggcaccc acgcggtggg ctacgtgatc
    20161 ttccgccggg tggtcgacgc ccaggacggc agccccgacg accgcggcat cgaaagcgac
    20221 tactccgccg acgagtacca gtgccgctga acgggccagc gcccggccgc ggaccgggcc
    20281 tcggacgcga tcggggctga tcgcatcggc ctgcgggcga aagcccgtgc cgcgtcaacc
    20341 gcgcctcacg cctgcgcgcc ggccgccagg gccgtggcga tgcgcacctc gccggtcagc
    20401 accttgtgga tcgggcaggc gttggcgatc tgcagcaggc gttcgcgctg ttcttcgctg
    20461 agctcgccgc gcaggacgat ctcgcgctca atgtcggtgc cggcggcggg cttgccggcg
    20521 gggttgaagc gcagcgtcac ttccacttgc gccagcggcc attgcttgcg ctcggcgtac
    20581 atgcgcacgg tgatcgcggt gcacgcgccc agactcgaca gcagcaggcg ttcgggcgag
    20641 ggcgcgctgt cgccgccgcc gacctcggcc ggttcgtcgg cctgccagcg gtgctcgccg
    20701 tcgtcgacga agctgaccgc gtagggcgcg gattcgccgc gggcgtggac gctggggacg
    20761 gtcgatgcgg tcatgcgggt ttcctcgggc ggggacgggg ctgcgctgcg gcgaacacga
    20821 cagtaagccc gcagggcggg cgacgacagg gggcgcgaac gcatgcagcg tttcatgccg
    20881 cgaacgccgc ggcgtcggcg gatggggtag gcgcggcgca gcggcgttgt ggtgcggcgg
    20941 acgatccgcg ccatcgttgc ggcaaggccg gaatccatgt cgatgttggc cggatcgtcg
    21001 cctgggcgcg tgtgcgtgcg gacacctcgc aagccggcac gctacaggat catcgcgatg
    21061 cagccctggg ttctcgcctt cgcgggaacg acgcagggtg gggtcgccgc gtcctggccc
    21121 gccgtgatcc cgcgaagccg gggccgaaga tttcagcatc gcgcttcgac cgaatcgggt
    21181 tctggccctc gcggaaacca cgcgggtgga ctcgccgcgt cctcgcctac cgtcatcccc
    21241 gcgaacgcgg ggatccacag acttcagcgc catgcttcga cggatctcgc gttcccgccc
    21301 cgcagccacg atgtcccgcc gcgccgactt tgcgtttccg ggccgatcgc cggtttcccg
    21361 cgtgaccgct tgtgcttttc cgagcgcacg gcgcgcaacc tgaagcgcgg cgtcgccgcg
    21421 aactcgcgca ggccggagcc ggcgtgcgat catccctcgc agccagcgca agcccgtaac
    21481 cagagcagta ggcaatgttc gaccgcagtc atttgatcgc acactggcgc caggcgccgc
    21541 cggcgcccgc aggcgcgctg gacatcgtgg aattcggccc cggcgacttc tcccagccgg
    21601 cctcggggca ggccatcggc gtggtccgcg gcgagcgcgc gacgttcgcc gaaccgctgc
    21661 atttctggat cgccgcgcag cgcgcgggcg agcgcttcgg tgcgcgcgtg gacggcgcgc
    21721 aagcgcatcc gggcgagacg cgctacatcg aggccgcact gtgccaaccg atcgatcgtg
    21781 cggtcttcgc gcgcatcgtc ggcgagtacg cggcgatgct gcgcgcgccg ctgcccgcgt
    21841 tcgtgcgcga gcccgagggc tggcgccgcg gcctgcgcat gtatcagcag ttcaacgacg
    21901 tggccgcgct ggtcgagacc gaccggcact acttcgtgtt cgcctggacc ttgtcgggct
    21961 gagcctcggc gccgggcccg gcgccgcatc gcgaatccgg tattgccgat ccgcagccgc
    22021 gaacctcgtt gcgccaacca cgcggaaccg cgatccgaaa cttcgattcg gaatctcgaa
    22081 ccgaagcttc gatccggacc ctcccaacac accgtcattc cggcgaaagc cggaactcct
    22141 cttgatcgtg cccttgccga tcgcgcgttc gcgaacgaat cactgcaccc ggatcgccag
    22201 atcccgtcgc cccaccgcct cgttgccgct gtaatcgcgc gccaccaccc gcaaggtgta
    22261 gtcgccggcc gcgaactcgc ccggcagcca cagcccttcg ttcacccggc cgccgcgcac
    22321 cgcattgctg agcacatagc gaaaacgggt gatcgcgctg ccgtgcacgg tgatgccgct
    22381 gccgggcgcg tagatcgtct gggtcgcatc gtccggcggc aagcggtcga actcgatgtt
    22441 catgcgcggg ctctcgtagc ccggcagcgg cgcgccctgc gcatcgagcc actgataacc
    22501 cagcgcatac agccccagcc gccgccgcgg cagattgtcg tcgacctggt cccagccctc
    22561 ggccacgatc tgcagccccg acagcgcgcg cgacacgatc aggcggccct cgcgcttgtc
    22621 cttcagcggc tggccgagcg cgtcgatcaa ctcgatgcgc tccagccgcg gcggcacgtg
    22681 gtcggcatag ccgacgaagt ccagcgcgat cgcgttgcgc tcgaagccgc tcgggcccag
    22741 gctcaggtgc acgtgcgcca tcgggttgat cgtgcccagc gtgtcgccga cggcgaaacg
    22801 ggtgccgcgg cgcaggcgca
//
