LOCUS       NZ_FNPT01000003        11281 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Lysobacter sp. yr284, whole genome shotgun sequence.
ACCESSION   NZ_FNPT01000003
VERSION     NZ_FNPT01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lysobacter sp. yr284
  ORGANISM  Lysobacter sp. yr284
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Lysobacter.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900107375.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 20:31:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,139
            CDSs (total)                      :: 5,059
            Genes (coding)                    :: 5,007
            CDSs (with protein)               :: 5,007
            Genes (RNA)                       :: 80
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 4 of 52
            Pseudo Genes (incomplete)         :: 50 of 52
            Pseudo Genes (internal stop)      :: 1 of 52
            Pseudo Genes (multiple problems)  :: 3 of 52
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:51:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 174414
            Orig. end                         :: 185695
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNPT01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11281
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11281
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11281
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6281](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6281)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    305..319
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            complement(661..2205)
                     /locus_tag="BLV01_RS07665"
                     /old_locus_tag="SAMN04487939_103123"
     CDS             complement(661..2205)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017390.4"
                     /locus_tag="BLV01_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_103123"
                     /product="M23/M56 family metallopeptidase"
                     /protein_id="WP_091796223.1"
                     /transl_table=11
                     /translation="MSAADVAFWLAQAGAQVLAGALAWFVGGAAHRRLRISHAAFGYWL
                     ALWLLALAPSVAASVWHASGAAAPAWPLPSGLPLPRLDAFAADAAPAHAAEAVATQPVV
                     DLAGALLALYLAGVACSLARWLRGGVALRGLLRAARDAGERLPGAHSRRELQALRARGV
                     QVVLSREAATAFAVGWPRRRVVVPEALAAHLDDAQLALVLRHEAAHLRRLDPERDALMR
                     LAQAALWFNPFLRMLAARVQLAAELRCDAAAIGADPGRRRPCAQAYLATLRLAAGRAAP
                     AGASAFARRRDPGQHQLRMQHMLHGDDRPRLRRGARLALLALALGGSAALAAAQAAGGG
                     DPARIAAPVAAPTNHEDTGTASTKPAADVRRLASPQAAANAAPAPIALAVPLADTRITS
                     RYGVSGGIRIRPHRGIDFAARRGTRVYAPAAALVVAATDRYPEGERYGKVVVLDHGDGW
                     QTLYAHLQDFDVHEGQRIAAGAPIGSSGASGQATGPHLHMEVLHDGQRVDPEPLLR"
     gene            complement(2202..2582)
                     /locus_tag="BLV01_RS07670"
                     /old_locus_tag="SAMN04487939_103124"
     CDS             complement(2202..2582)
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036297 - interstrand cross-link repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408657.1"
                     /locus_tag="BLV01_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_103124"
                     /product="crosslink repair DNA glycosylase YcaQ family
                     protein"
                     /protein_id="WP_091796225.1"
                     /transl_table=11
                     /translation="MPPRPSNAELELLKCLWRQQPLSARELHNAVGEQLQWSYSSTRKT
                     LERMLEKGLVASADHHGLMVFRAAVAKLPTLAALSADFARRVLEIDGPLPVQAFADSRL
                     LDQGELEQLEAMLRDADPERPR"
     gene            complement(2844..3194)
                     /locus_tag="BLV01_RS07675"
                     /old_locus_tag="SAMN04487939_103125"
     CDS             complement(2844..3194)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV01_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487939_103125"
                     /product="hypothetical protein"
                     /protein_id="WP_091796227.1"
                     /transl_table=11
                     /translation="MDRRHLRVPPGLARPLAAALACIAALAACKPSVSERQVREDFATL
                     QATGTVPGKARLQRIEFTDGWSDGADFEVYFCLPASDGPGRGCEQRNIGLSYQQREGRW
                     RLFSVQAEQAVE"
     gene            3639..4820
                     /locus_tag="BLV01_RS07680"
                     /old_locus_tag="SAMN04487939_103126"
     CDS             3639..4820
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013700.4"
                     /locus_tag="BLV01_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_103126"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_091796229.1"
                     /transl_table=11
                     /translation="MLPRPFASALIWAALVLAAAPARAAPVDTLDLAVPQVPAAVVVEG
                     RQRLLYELHLTNFGAAPLRLQAVSVLDAGSGAVLAGWRGEALAARGRIVGARDAALGDA
                     LQPGQRAVVFLELDLPAPMPKALRHRVEFSSAAAAPGPADTGRAEGAQVEGGQVEGGQV
                     APRPAAALPLAAPLRGGPWAAVYAPHWPRGHRRVFYALDGRARLPGRYAIDFVRVDAQG
                     RTARGDADLAANALGYGEPVLAVADAVVAAARDGIGESARVSAHPRHDFDRAPGNYVAL
                     ALADGRYAVYEHLRPGSLSVRAGERVRRGQVIGELGFTGDSTGPHLHFHVADAPAPLAG
                     EGVGYAFEAFGLLGHYPGAAGLGERPWQARADDVAAQRRNELPESNAVIEFAR"
     gene            complement(5001..6281)
                     /locus_tag="BLV01_RS07685"
                     /old_locus_tag="SAMN04487939_103127"
     CDS             complement(5001..6281)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="BLV01_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_103127"
                     /product="YcaO-like family protein"
                     /protein_id="WP_175485814.1"
                     /sec_met_domain="YcaO (E-value: 7.6e-47, bitscore: 154.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPLERERSLDEAERALRDFLDAQGWRADVQRVGAPFAATICSLY
                     DQADGRLLGNGFGKGEADPARVGALFEAVEHLFTGKAPAHAVLSLRSGADCLADPLLAA
                     LPFRAAFAQQPERRLACRRYRAFAAGEPDATLPLFLSYPTYLDWRPPQDDFDYASALRF
                     GSNNGTAIGSSLAEAAVHAIGELIERDAWSLFLTAHFLGDPAAHGYLLAPDELPAPLAR
                     RLGEAEAQLQRRIALIDATSDLGVPCFIATATDLPDGESIHPCGYGASLYPEHAAMRAI
                     TELVQALELPRLQPRLAGYSQAVLGALSDYPKLRDCAVFALDRARLRRRRWDFQTPPPL
                     PPAALLERLTARLRARGIDLHYAINHDEPGRFCVVNVVSLALERFFLVCSGIVMAPGQR
                     GRELLAGRLPVPGSAAAPDCEASLALA"
     gene            complement(6404..6544)
                     /locus_tag="BLV01_RS26185"
                     /old_locus_tag="SAMN04487939_103128"
     CDS             complement(6404..6544)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV01_RS26185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487939_103128"
                     /product="hypothetical protein"
                     /protein_id="WP_157490371.1"
                     /transl_table=11
                     /translation="MKKTIDMPLIVKSGVRLIEPTSTLEAHDVQPEITADELDFLEAHA
                     K"
     gene            complement(6744..7760)
                     /locus_tag="BLV01_RS07690"
                     /old_locus_tag="SAMN04487939_103129"
     CDS             complement(6744..7760)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013694.4"
                     /locus_tag="BLV01_RS07690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_103129"
                     /product="transporter"
                     /protein_id="WP_091796233.1"
                     /transl_table=11
                     /translation="MRIADASYGSNEDGLIWGYRFVPGQPAQPISTDAVAAFLAAPADG
                     DGRGFLWLHFSLSNTGSERYLRRALRMPDAFYDSLRSEVGSTRLELDDNALIAVVHDVL
                     FDSSFDASEVGTTSLCIGPRLLVSARLRPLRSVDQLRAAVRSGQVFRSPVELLAHLLRD
                     QASVLGEILRKCTVQVDRIEDRLLDNRIATDRKQLGALRRSLVRLQRLLAPEPTALFRL
                     LNRPPDWIGRDDIGDLQQAAEEFSTAIGDSAALVERVKLIQEELAALVNEQTGRTLFVL
                     TVVTVVALPINLVAGLFGMNVGGIPLADNPHGFLSVVIGLCVLTAVLAYAAFGRRRD"
     gene            complement(7915..8223)
                     /locus_tag="BLV01_RS07695"
                     /old_locus_tag="SAMN04487939_103130"
     CDS             complement(7915..8223)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV01_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487939_103130"
                     /product="hypothetical protein"
                     /protein_id="WP_091796235.1"
                     /transl_table=11
                     /translation="MDARREPLPDPARLRALLSPSVIVSLALALTAAVLALAYLFQARA
                     PAARGAAPAHTVPGRAGAPAGSAAALPAPVPEPVEFRCVDGLRVRKQGSSYTGDGRC"
     gene            complement(8470..9663)
                     /locus_tag="BLV01_RS07700"
                     /old_locus_tag="SAMN04487939_103131"
     CDS             complement(8470..9663)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042925 - benzoate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0042919 - benzoate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016904738.1"
                     /locus_tag="BLV01_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487939_103131"
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="WP_091796237.1"
                     /transl_table=11
                     /translation="MPHLRDLSLSAVVAGFVAVLVGFTSSAAIVFSAAQASGADEAEIA
                     SWMWALGLGMAATCIGLSLRYKVPVVTAWSTPGAAMLITGAAGLPLAEAIGAFVISAAL
                     TVALGFSGWLERALARLPASLAAGMLAGVLLRFGLNVFTSMQHSFALVLAMLLGFLLAR
                     RWLPRYAVLVALAVGIAVAALQGGLHLDKLQLAVALPVWTTPRFSLAATVGVAIPLFVV
                     TMASQNVPGIAILRAHGYRDTPASPLIGWTGLANLLLAPFGAFALCLAAITAAICMGED
                     AHEDPRKRYFASVAAGGFYLLTGVFGATVAAAFAAFPQALVLAIAGIALLATIGNALAA
                     ALADPQERDPALITFLVTASGFTALQIGSVFWGMVAGVVATLVLRLRKPRAAADAVR"
     gene            9848..11074
                     /locus_tag="BLV01_RS07705"
                     /old_locus_tag="SAMN04487939_103132"
     CDS             9848..11074
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV01_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04487939_103132"
                     /product="hypothetical protein"
                     /protein_id="WP_091796239.1"
                     /transl_table=11
                     /translation="MSARTAVSYRPPRRLALALPLMLAALPAPARASDHLDSPTVIADP
                     RADIGDLYAWMQPDGRRLNLAMTVVGHGFSDRLRYVFRIDSARRFGGADASVEIVCRVP
                     AAERVECSADGIDAARGDARGEAGLWGERHRLRVFAGLRDDPFYNNVRGTRAAYQVAAA
                     ALAAGAPLDAARCARFEPATVRAIAEQWRHTDGDPARNFLAGWTPAALVVQIERKAVDR
                     GGPLLAVWAAVESSERRIDRAGRVLTGNALLGTLDGEEASDRLKERYNAGAPADGAEFA
                     PQIERGLALYDAFDGRCGNALLAASEPARRYRALARLLADDRLWVDSRRRRCQRPFAVE
                     LAQAAGRRADRGDCGGRTPLQAAINVYRSLLVDASVDGVSDGLQRDEKTPSVDRFPFLA
                     PADAAGYSP"
ORIGIN
        1 gcgctgggct tgaagccgtt gccgctgtgc ttgagcgcga agctgagccg gtcgcggtcg
       61 cggcgcgcct gcttggccag gacgatgttg atcgtgccgg cgatggcttc gccgcgcagg
      121 tcggcggtgg tggtgcgcag cagttcgatg cgctcgacct gatccggccg cagcgtggcc
      181 gggtcgaagc ccggcggcgc ggcgcggccg tcgatcaata cctgggtgta gcccttgccg
      241 agcccgcgca gggcgatcgc gccgccgccg gcgccgtcgg acagcgacac gccgggcagg
      301 cgcttgagcg cgtcggccag ggtgtcgtcg ccgaagcggg tcaactcgtc gctggagacg
      361 acgatgcgcg aggcggtgtc gtcgcggcgc gggtcgtagt cgcgcgcctg tacggtgacg
      421 gtgtccagcc gggtgggcgc gtcggcggcg gcgtcctggg acggcggttg cgcggccgcg
      481 gcggcggccg aggcgagggc gagcgcgctg cacagggcgg tgcggcgcag ggcggcggtg
      541 gggcggggta cgggcatcgg tgggcgatcc ggtgggctgc gcggggccgg cggcgggcaa
      601 gccgccgccc tcccgcgacg gcgggcgaac gaaagacgga ttgaggtagg agcggtgcgc
      661 tcagcgcagc agcggttcgg gatccacgcg ctggccgtcg tgcaggactt ccatgtgcag
      721 gtgcggcccg gtggcctggc cgctggcgcc ggagctaccg atcggcgcgc cggcggcgat
      781 gcgctggcct tcgtgcacgt cgaagtcctg cagatgcgcg tacagcgtct gccaaccgtc
      841 gccgtggtcg agcaccacca ccttgccgta gcgctcgcct tcgggataac ggtcggtggc
      901 ggcgaccacg agcgcggcgg ccggcgcgta cacgcgggtg ccgcggcgcg cggcgaagtc
      961 gatgccacgg tgcgggcgga tgcggatgcc gccgctgacg ccgtagcggc tggtgatgcg
     1021 ggtatcggcg agtgggacgg cgagggcgat gggcgcgggt gccgcgttcg ccgcggcctg
     1081 cggcgacgca aggcggcgca cgtcggcggc gggcttggtc gaagccgtgc cggtgtcctc
     1141 gtggttcgtg ggagcggcga cgggcgcggc gatccgcgcc ggatcgccgc cgccggcggc
     1201 ctgcgccgcg gccaacgcgg cgctgccgcc cagcgccaac gccagcagcg ccaggcgcgc
     1261 gccgcggcgc aggcgcggcc ggtcgtcgcc gtgcagcatg tgctgcatgc gcaattggtg
     1321 ctggcccggg tcgcggcgac gggcgaacgc gctggcgccg gccggcgcgg cgcggccggc
     1381 ggccaggcgc agggtggcga gataggcctg cgcgcagggc ctgcggcggc cgggatcggc
     1441 gccgatcgcc gcggcatcgc agcgcagttc cgcggccagt tgcacgcgtg cggccagcat
     1501 gcgcaggaac gggttgaacc acagcgccgc ctgcgcgagc cgcatcagcg cgtcgcgttc
     1561 cgggtccagg cggcgcaggt gcgcggcttc gtggcgcagc accagcgcga gctgcgcgtc
     1621 gtccaggtgc gcggccagcg cctcgggcac gaccacgcgg cggcgcggcc agcccacggc
     1681 gaaggcggtg gcggcctcgc ggctcaacac cacctgcacg ccgcgcgcgc gcagcgcctg
     1741 cagttcgcgc cggctgtgcg cgccgggcag gcgctcgccg gcgtcgcgcg cggcgcgcaa
     1801 cagcccgcgc agcgcgacgc cgccgcgcag ccagcgcgcc aggctgcagg cgacgccggc
     1861 gaggtagagc gcgagcaaag cgccagccag gtccacgacc ggttgcgtcg cgacggcctc
     1921 ggccgcgtgc gccggcgcgg cgtcggcggc gaacgcgtcc agccgcggca acggcaggcc
     1981 ggacggcaac ggccacgccg gtgcggcggc gccgctggcg tgccagaccg atgcggcgac
     2041 gctcggcgcg agcgccagca gccacagcgc cagccagtag ccgaacgcgg cgtgggaaat
     2101 gcgcaggcgc cggtgcgcgg cgccgcccac gaaccacgcc agcgcgccgg cgagcacctg
     2161 cgcgccggcc tgcgccagcc agaacgcgac gtccgccgcg ctcatcgcgg ccgctccggg
     2221 tcggcgtcgc gcagcatcgc ttcgagttgt tcgagttcgc cctggtcgag caggcggctg
     2281 tcggcgaagg cctgcaccgg cagcggcccg tcgatctcca gcacccgccg ggcgaagtcg
     2341 gcgctgagcg cggccagggt cggcagcttg gcgaccgcgg cgcggaacac catcaggccg
     2401 tggtggtcgg cgctggcgac caggcccttc tcgagcatgc gttcgagcgt cttgcgggtc
     2461 gaggagtacg accactgcag ttgctcgccg accgcgttgt gcagttcgcg cgcgctcagc
     2521 ggctgttgcc gccacaggca tttgagcagt tccagttcgg cgttggacgg acgtggcggc
     2581 atggcggcag atgggtgtgg aggttgtgtc gccaacatac gacacttgtc gcatgcactc
     2641 aagcggcgcg gcgatgccgc caacggcggc atgcggccgg gacctgcggt gcgttcggtt
     2701 ctcgatcccg gcgcggtggc gcaagacgcg gcggtccgtg cggcgtgcgg gaggtcagct
     2761 cgttcggcac gacggcgccc aagcgcggct ggtgcctgcg tcgcaggccg gcgcggccgg
     2821 cgaaggggcg cggcagctcg gggctactcg accgcttgct cggcctgcac cgaaaacaaa
     2881 cgccaacggc cttcgcgctg ctggtacgac aagccgatgt tgcgctgctc gcagccgcgg
     2941 ccggggccgt cgctcgcggg caggcagaaa tagacttcga agtcggcgcc gtcgctccag
     3001 ccgtcggtga actcgatgcg ctgcagccgg gccttgcccg gaaccgtgcc ggttgcctgc
     3061 aaggtggcga agtcttcgcg cacctggcgc tcggacacgc tgggcttgca cgcggcgagc
     3121 gcggcgatgc aggccagcgc ggcggcgagc gggcgggcga ggccgggtgg gacgcggagg
     3181 tggcgacggt ccatgtcggg cgcacagcgg aagcggcctc cctggccgcg ggaaggcgat
     3241 cattcgcgat gcgcgcgggg aacgcaagcg cgccgcaggg ccggatcgca cgacggcgtt
     3301 cgcgctttcg ccggcgttgc ggcgaagcgc cgcgagggcg gccgcgggtg gccggagtcg
     3361 cggccggatt ccgtcgcggc ggcgccgatc gctgggcaac gaacgctgcg cgcgcggcgc
     3421 ttcgggccga ggccgggcgg tgcgcccggc gacgttgtcg ggttgcgcag cggcgggcgc
     3481 cgagcgctgc gcaacgagcg ttgcgcgcgg cgtccggacc gcccgcgcgc agcgcgaatg
     3541 cggaccgccg cgcgcgcgga tgacaatcgg caggggacgc cgacggccgc gctggcggaa
     3601 gctgcctcgc cgatccgcgc ccggcctgga ccctacgcat gttgcctcgc ccgttcgctt
     3661 ccgccctgat ctgggccgcg ttggtcctcg ccgccgcgcc cgcgcgcgcc gcaccggtgg
     3721 acacgctcga cctggcggta ccgcaggtcc cggccgcggt cgtggtggaa gggcgccagc
     3781 gcctgctgta cgaactgcac ctgaccaatt tcggcgccgc gccgctgcgg ctgcaggcgg
     3841 tgagcgtgct cgacgcgggc agcggcgcgg tgctggcggg ctggcgcggc gaggcgctgg
     3901 ccgcgcgcgg ccgcatcgtc ggcgcgcgcg acgcggcgct gggcgatgcg ctgcagcccg
     3961 gccagcgcgc cgtcgtgttc ctggaactgg acctgccggc gccgatgccg aaggcgctgc
     4021 gccatcgggt cgagttttcc agcgccgccg ccgcgccagg cccggccgat accggccgtg
     4081 cagaaggcgc gcaggtggaa ggcggccaag tggaaggcgg gcaggtggcg ccgcggccgg
     4141 cggccgcgct gccgttggcg gcgccgctgc gcggcgggcc gtgggcggcg gtgtacgcgc
     4201 cgcactggcc gcgcgggcac cggcgggtgt tctacgccct cgacggccgc gcgcgcctgc
     4261 ccggccgcta cgccatcgac ttcgtccgcg tcgacgcgca aggccgcacc gcgcgcggcg
     4321 acgccgacct cgccgccaac gcgctgggct acggcgagcc ggtgctggcg gtggccgatg
     4381 cggtggtcgc cgcggcgcgc gacggcatcg gcgagagcgc gcgcgtgtcc gcgcatccgc
     4441 gccacgattt cgaccgggcg cccggcaact acgtggcgct ggcgctcgcc gacggccgct
     4501 atgcggtgta cgaacacctg cggcccggca gcctgagcgt gcgtgccggc gaacgcgtgc
     4561 gccgcggcca ggtcatcggc gaactcggct tcaccggcga ctcgaccggg ccgcacctgc
     4621 atttccacgt cgccgacgcg cccgcgccat tggccggcga aggcgtgggc tatgccttcg
     4681 aggcgttcgg cctgctcggg cattaccccg gcgcggcggg gctcggcgag cgtccgtggc
     4741 aggcgcgcgc cgacgacgtc gcggcgcagc gccgcaacga gttgcccgag tccaacgcgg
     4801 tgatcgagtt cgcgcgctga gcgcagttgg cgatgtcgtg gttgcgggcg ggccgcgacg
     4861 gatgcgcagc gcggctaggc cgttgtggga ggggcttcag ccccgacgct tttcgatccg
     4921 gtcgccgagc gcggacacaa aagcgtcggg gctgacgccc ctcccacaac agccccgcag
     4981 gcgggcttgt cgtgccggct tcacgccagc gccaacgacg cctcgcagtc cggcgccgcg
     5041 gcgctgcccg gcaccggcag gcgcccggcc agcaactcgc gcccgcgctg gcccggcgcc
     5101 atgacgatgc cggagcagac caggaagaac cgctccagcg ccagcgacac cacgttgacc
     5161 acgcagaaac gtccgggttc gtcgtggttg atcgcgtagt gcaggtcgat gccgcgcgcg
     5221 cgcaggcgcg cggtcagccg ttccagcaac gcggccggcg gcagcggcgg cggcgtctgg
     5281 aagtcccagc ggcggcggcg caggcgcgcg cggtcgagcg cgaacaccgc gcagtcgcgc
     5341 agcttcggat aatccgacaa ggcgcccagc accgcctgcg aatagccggc gagccgcggc
     5401 tgcaggcgcg gcagttccag cgcctgcacc agttcggtga tcgcgcgcat ggccgcgtgt
     5461 tcggggtaca gcgaggcgcc gtagccgcag ggatggatcg actcgccgtc gggcaggtcg
     5521 gtcgcggtgg cgatgaagca gggcacgccg aggtcgctgg tggcgtcgat cagggcgatc
     5581 cggcgctgca gctgcgcctc ggcctcgccc aggcgccggg ccagcggcgc cggcagttcg
     5641 tccggcgcca gcaggtagcc gtgggcggcc ggatcgccga ggaaatgcgc ggtcaggaac
     5701 agcgaccagg cgtcgcgctc gatcagttcg ccgatcgcgt gcaccgcggc ctcggccagg
     5761 ctgctgccga tcgcggtgcc gttgttggag ccgaagcgca gggcgctggc atagtcgaaa
     5821 tcgtcctgcg gcggacgcca gtcgagatag gtggggtagg acaggaacag cggcaaggtc
     5881 gcatccggtt cgcccgcggc gaaggcgcgg tagcggcggc aggcgagccg gcgctcgggc
     5941 tgctgggcga aggcggcgcg gaacggcagc gccgccagca gcggatcggc caggcagtcg
     6001 gcgccgctgc gcaggctcag caccgcgtgc gcgggcgcct tgccggtgaa caggtgttcg
     6061 accgcttcga acagcgcgcc gacccgcgcc gggtccgcct cgcccttgcc gaagccgttg
     6121 ccgagcaggc gcccgtcggc ctggtcgtag agcgagcaga tcgtcgccgc gaacggcgcg
     6181 ccgacgcgct gcacgtccgc gcgccagcct tgcgcgtcga ggaagtcgcg cagcgcgcgc
     6241 tcggcctcat cgaggctgcg ttctcgttcc aggggaatca tcggttgcgc tctccctcgc
     6301 gctggattcg ccgcgcgccc ggcccgcggc ggcggtgcga cggcacgcag gcgcgcctgc
     6361 atgccgtcgc cgcgccggcc tgcgccggtc gcgctgttgc ggcttacttg gcgtgcgctt
     6421 ccaggaaatc cagttcgtcg gcggtgattt ccggctggac gtcgtgggct tccagggtcg
     6481 aggtcggctc gatcagacgc acgccgctct tcacgatcag cggcatatcg atggtcttct
     6541 tcatggtgtg ctccctccaa tggtcgatgg gttgttcctt cgtgcctcag cgcagcggac
     6601 cgttgcgggc ctgcgccctc ccggcggctg ccgctcctct ataccaaagc cgcccgcggc
     6661 ctgcggggcg gaccgcggga tttgtgatgc aagggcgcag tgcgtgatcg gcgcgcgcat
     6721 tcagctgcgc gcgggatgtg atgtcagtcg cggcggcggc cgaacgcggc gtaggccagg
     6781 accgcggtca gcacgcacag cccgatcacc acgctgagga agccgtgcgg gttgtcggcc
     6841 agcgggatgc cgccgacgtt catgccgaac aggccggcga ccaggttgat cggcagggcc
     6901 actacggtga ccacggtcag cacgaacagg gtgcgcccgg tctgctcgtt gaccagcgcc
     6961 gccagttctt cctggatcag cttgacccgc tcgaccagcg cggcggagtc gccgatcgcg
     7021 gtggagaact cttcggcggc ctgttgcagg tcgccgatgt cgtcgcggcc gatccagtcc
     7081 ggcgggcggt tgagcagccg gaacagcgcg gtcggctccg gcgccagcag ccgctgcagg
     7141 cgcaccaggc tgcggcgcag cgcgccgagc tgcttgcggt cggtggcgat gcggttgtcg
     7201 agcaggcggt cctcgatccg gtcgacctgc acggtgcact tgcgcaggat ctcgccgagc
     7261 acgctggcct ggtcgcgcag caggtgggcc agcagctcca ccggcgagcg gaacacctgg
     7321 cccgagcgca ccgccgcgcg cagctggtcg accgagcgca acgggcgcag ccgcgcgctg
     7381 accagcaggc gcgggccgat gcacaggctg gtggtgccga cctcggaggc gtcgaagctg
     7441 gaatcgaaca gcacgtcgtg gaccaccgcg atcagcgcgt tgtcgtccag ctccagccgg
     7501 gtcgagccga cctcgctgcg caggctgtcg tagaacgcgt cgggcatccg cagcgcgcgg
     7561 cgcaggtagc gttcgctgcc ggtgttggac agggagaagt gcagccacag gaagccgcgg
     7621 ccgtcgccgt cggcgggcgc ggcgaggaag gcggcgaccg cgtcggtgct gatcggctgc
     7681 gccggctggc ccgggacgaa gcgatagccc cagatcaggc cgtcttcgtt ggaaccgtag
     7741 ctggcgtcgg cgatgcgcat cgaagcggcg atccgggggc ggaaggaaca ggccgcctac
     7801 gctagcccaa agcggcggcg gcgtcatggc gggcgtgccg cgtcctgcgc gcgtgcggcg
     7861 gcgcgggcgc ggccgaccca cagcgcgggc cggcggcggc gcggcgcggg cggctcagca
     7921 gcggccgtcg ccggtgtagc tgctgccttg cttgcgcacg cgcaggccgt cgacgcagcg
     7981 gaactcgacc ggttcgggca ccggtgccgg cagcgccgcg gcgctgccgg ccggcgcgcc
     8041 ggcgcggccg ggcacggtat gcgcgggcgc ggcgccgcgc gcggccggtg cgcgcgcctg
     8101 gaacagatag gccagggcca ggaccgcggc ggtcagcgcc agcgccaggc tcacgatcac
     8161 gctggggctg agcagggcgc gcaggcgggc cgggtccggc agcggttcgc ggcgggcatc
     8221 catgcggcgg gtttccgtgg tggggtgggg ccgagcatac ccgccggacg ggcgcgccag
     8281 cgcaaggggg cgggcccgat gtttgccgct gcgcggcgat gcggcttggc ggcgagcgga
     8341 cccgacagcg tcgggactga agcccccgcc acaaacgcca cgacaacctg tgggacgtcc
     8401 tccaggccct acgctttccg atccggtccg atggcgtttc gacgcggccg cagcctcgcc
     8461 acaaccgcct cagcgcaccg cgtccgccgc cgcccgcggc ttgcgcagcc gcagcaccag
     8521 cgtggcgacc accccggcga ccatgcccca gaacaccgag ccgatctgca acgcggtgaa
     8581 gcccgaggcg gtgaccagga aggtgatcag cgccggatcg cgttcctgcg ggtcggccag
     8641 cgccgcggcc agggcgttgc cgatggtggc gagcagggcg atgccggcga tggccagcac
     8701 cagcgcctgc gggaacgccg cgaacgcggc cgccacggtc gcgccgaaca cgccggtgag
     8761 caggtagaac ccgccggccg cgaccgaggc gaagtagcgc ttgcgcggat cttcgtgcgc
     8821 gtcctcgccc atgcagatcg cggcggtgat cgccgccagg cacagcgcga acgcgccgaa
     8881 cggggcgagc agcaggttgg ccaggccggt ccagccgatc agcggcgagg ccggcgtgtc
     8941 gcggtagccg tgcgcgcgca ggatcgcgat cccgggcacg ttctgcgagg ccatggtcac
     9001 cacgaacaac ggaatggcga cgccgacggt ggcggcgagc gagaaccgag gcgtggtcca
     9061 caccggcaac gccaccgcca gttgcagctt gtccaggtgc agcccgccct gcagcgccgc
     9121 caccgcgatg ccgaccgcga gcgcgaccag caccgcatag cgcggcagcc agcgccgcgc
     9181 cagcaggaag cccagcagca tcgccaacac cagggcgaag ctgtgctgca tcgaagtgaa
     9241 cacgttgagc ccgaaacgca gcagcacccc ggccagcatg cccgcggcca ggctcgccgg
     9301 cagccgcgcc agcgcccgtt cgagccagcc gctgaagccc agcgcgacgg tcagcgcggc
     9361 gctgatcacg aacgcgccga tcgcctcggc cagcggcagc ccggccgcgc cggtgatcag
     9421 catcgccgcg ccgggcgtgg accaggcggt gaccaccggg accttgtagc gcagcgacag
     9481 gccgatgcag gtggcggcca tgccgagccc gagcgcccac atccacgaag cgatctcggc
     9541 ctcgtcggcg ccgctggcct gggcggcgga gaacacgatc gcggccgaac tggtgaaacc
     9601 gaccagcacc gcgacgaatc cggcgacgac ggcggacaag gacagatcgc gcagatgcgg
     9661 catgcgggcg ccgggacagg ggagaggcga catcatgcgg catcggccgc gccggcggct
     9721 gtgcgctggc ggcgatttcg accgcgtgcg cgggcggcca gccggtgccg cgcatcgcta
     9781 aagattccga cagcgcggcc gccgccgcgc cgctgtactg gcgcctcctt cgccaggcgc
     9841 cgcccgcatg tccgcccgca ctgccgtttc gtaccgtccg ccgcgccggc tggcgttggc
     9901 gctgcccctg atgctggccg ccttgccggc gccggcgcgc gcgtccgacc acctggattc
     9961 gcccaccgtc atcgccgacc cgcgcgccga catcggcgat ctctacgcct ggatgcagcc
    10021 cgacgggcgc cgcctgaacc tggcgatgac cgtggtcggc cacggcttct ccgaccgctt
    10081 gcgctacgtg ttccggatcg acagcgcgcg ccgcttcggc ggcgccgacg ccagcgtcga
    10141 gatcgtctgc cgcgtccccg ccgccgagcg cgtcgaatgc agcgccgacg ggatcgacgc
    10201 ggcgcgcggc gacgcccgcg gcgaggccgg gctgtggggc gagcgccatc gcctgcgggt
    10261 gttcgccggc ctgcgcgacg acccgttcta caacaacgtg cgcggcaccc gcgccgccta
    10321 ccaggtcgcc gccgcggcgc tggctgccgg cgcgccgctc gacgccgcgc gctgcgcccg
    10381 cttcgaaccg gccaccgtgc gggccatcgc cgaacaatgg cgccacaccg acggcgaccc
    10441 ggcgcgcaac ttcctcgccg gctggacgcc ggccgcgctg gtggtgcaga tcgagcgcaa
    10501 ggcggtcgac cgcggcggcc cgctgttggc ggtgtgggcg gcggtggaat cttccgagcg
    10561 ccgcatcgac cgcgccgggc gcgtgctgac cggcaacgcg ctgctcggca cgctcgacgg
    10621 cgaagaggcc agcgaccggc tcaaggagcg ctacaacgcc ggcgcgccgg ccgacggcgc
    10681 cgagttcgcg ccgcagatcg agcgcgggct ggcgctatac gacgccttcg atggccgctg
    10741 cggcaacgcc ttgctggccg cgtccgaacc ggcccggcgc tatcgcgcgc tggcgcggtt
    10801 gctcgccgac gaccgcctgt gggtcgacag ccgccggcgc cgttgccagc gcccgttcgc
    10861 ggtggagctg gcccaggccg cgggccgccg cgcggatcgc ggcgattgcg gcgggcgcac
    10921 gccgttgcag gcggcgatca acgtctaccg ctcgctgctg gtggacgcca gcgtcgacgg
    10981 cgtcagcgac ggtttgcagc gcgacgagaa aacgccgtcg gtcgatcgct tcccgttcct
    11041 ggccccggcg gacgcggcgg ggtattcgcc gtgagccgcg gcgggcctgc cgcactgcgg
    11101 gcgccagcgc cgcagcggcg gtgtgcttgc ctgcggcggc gtcgaccgcg gccgcgccgg
    11161 cgtggtcgcc gctgctgctc gcgctggccg cgcccgcgca ttggctggtc gcgcgcggcg
    11221 cggccgtcgc gatcaaggtc gcggccagct ggctgctggc cgtggcgctg ctggcgctgt
    11281 c
//
