LOCUS       NZ_FNNQ01000030         6124 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Marininema mesophilum strain DSM 45610, whole genome shotgun
            sequence.
ACCESSION   NZ_FNNQ01000030
VERSION     NZ_FNNQ01000030.1
KEYWORDS    WGS; RefSeq.
SOURCE      Marininema mesophilum
  ORGANISM  Marininema mesophilum
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Marininema.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900106775.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:02:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,196
            CDSs (total)                      :: 3,130
            Genes (coding)                    :: 3,066
            CDSs (with protein)               :: 3,066
            Genes (RNA)                       :: 66
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (5S, 16S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 21 of 64
            Pseudo Genes (incomplete)         :: 50 of 64
            Pseudo Genes (internal stop)      :: 5 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 6124
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNNQ01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..5315)
                     /locus_tag="BLV90_RS15730"
                     /old_locus_tag="SAMN05444487_1301"
     CDS             complement(<1..5315)
                     /NRPS_PKS="Domain: Condensation_LCL (30-328). E-value:
                     4.8e-112. Score: 365.8. Matches aSDomain:
                     nrpspksdomains_BLV90_RS15730_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (493-892). E-value:
                     2.5e-114. Score: 374.0. Matches aSDomain:
                     nrpspksdomains_BLV90_RS15730_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (996-1064). E-value: 2.8e-26. Score:
                     83.5. Matches aSDomain: nrpspksdomains_BLV90_RS15730_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1082-1385). E-value:
                     8.1e-113. Score: 368.3. Matches aSDomain:
                     nrpspksdomains_BLV90_RS15730_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1550-1768). E-value:
                     4.9e-67. Score: 218.2. Matches aSDomain:
                     nrpspksdomains_BLV90_RS15730_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003192749.1"
                     /locus_tag="BLV90_RS15730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_1301"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_143035084.1"
                     /sec_met_domain="Condensation (E-value: 9.5e-83, bitscore:
                     264.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-121, bitscore:
                     393.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.4e-19, bitscore:
                     56.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNNLIERLSTLSPEKRMLLEKQLHKNKKREPSPLSYAQQRLWFM
                     DRFTPNSALYNIPGVWRLRGEWSIESLEKGLNALIERHEVLRTVIREVDGQPVQQIQPF
                     MPRKLPVIHLMDLSIEEREAEMNRLIQEEAESPFDLAQGPLMRAQCIQVDEKEWMFLCT
                     MHHIISDGWSMGVFLEELLTLYKDEAAELPLLPIQYADFAKWQRKWIEEEGLDTQLQYW
                     QEELSGELPVLQWPTNRVRPVAQTYHGAVHQVHFPLHLVEKLKEVSREEGSTLFMTLLA
                     AYQGFLSRYTGQEDILVGSPIANRNHQEIEGLIGFFVNTLVYRADVSGNPTFRELLAQV
                     RQKALKAYEHQDIPFEKIVEAVQPERSNSHSPIFQTSFTLQDTASRKSRDLSGKTMEPV
                     DIHTSVAKFDLTVVMEEKAEGLWIAFEYNTDLFDGATIERMARHFENWLNEVAYHSDKT
                     LGSLNLMAEEEKQQLLVDWNDTTVVYPRALTVHELFEEQAMSRPEAIAVVYEDQELTYR
                     KLNERANQLAHYLQKQGVGAESLVGLCMDRSPDMIVGLLGILKAGGAYVPLDPTYPLDR
                     LTYMIEHTQIRILLTKDKVADHIQNGSIKKIDLDEERLYILAENNCNLNHHINSSHLSY
                     VMFTSGSTGKPKGVCIPHRGVVRLVKETDYIHFTSDDTSLQVASISFDAATFEIWGSLL
                     NGGKLVLFPGSSFSLEELGKVIQDSSITIMCLTTSLFHQVVDFNQKALHGVKQLLVGGD
                     VLSAAHVRKVLQSIPGCRVINGYGPTENTTCTCSYSMTDPDEVSMSIPIGRPIANTSVY
                     ILDRNLQPVPVGIPGELYVGGDGLAHGYLYAEQQTAEKFIPHPFSEHPEEKLYKTGDLV
                     RYLPDGNLEFLGRIDNQVKIRGFRIELGEIEGALNEISSIQESVVMVQEYDRGDKRLVA
                     YVVGEGSVAEWKAHLSDQLPSYMVPAYFVVLDAFPLTSNGKIDRKALPIPDGKQVGGQY
                     IAPRTPLEELVVSVWEPILGLENIGAQDSFFELGGHSLLATQVASRLQEAFQIELSIRE
                     LFAYPTVEALATRLDELRQGEKATLPPLKPMERTEPVPLSYAQQRLWFIDRFTPNSALY
                     NIPGVWRLKGDWSIEGLEKGLNALIERHEVLRTVIHEVDGQPVQQVPPFMPKELPVINL
                     MHLSFAEREAEMHRLIQEEAELPFDLAQGPLMRAKCIQIDEKEWMFLCTMHHIISDGWS
                     MGVFLEELLTLYKNVLDESPAEKLPPLPIQYADFAQWQRKWMEEEGLDTQLQYWQEELS
                     GELPVLQWPTNRVRPVEQTYRGAVHQVLLPPYLVEKLKEVSREEGSTLFMTLLAAYQGF
                     LSRYTGQDDILVGSPIANRNHQEIEGLIGFFVNTLVYRADVSGNPTFRDLLAQVRQKAL
                     KAYEHQDIPFEKIVEAVQPERSTSHSPIFQTLFTLQDTASWKLPYLPGKKMELVDNHVS
                     TAKFDLTVAMVEKAEGLWAAFEYNTDLFDRATIERMARHFENWLHEVAHHSEKALGSLD
                     LMAEEEKQQLLVEWNDTTVAYPQALTIHELFEEQAMSRPEAIAVVYEDQQLTYRELNER
                     ASQLAHYLQKQGVGSESLVGLCVDRSPDMVVGLLGILKAGGAYVPLDPTYPEKRLQYIV
                     EDAGIQILVTQAHLQEQEKLQKTVKTIYLDQDQESIARESVLSPKVEVTAQNLAYVIYT
                     SGSTGNPKGVMVEHRNVIRLFQATEPWYQFNEQDTWTLFHSYAFDFSVWELWGALLYGG
                     RLVVVPYWISRSPKD"
     source          1..6124
                     /db_xref="taxon:1048340"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0131193_130"
                     /organism="Marininema mesophilum"
                     /strain="DSM 45610"
                     /type_material="type strain of Marininema mesophilum"
     region          1..6124
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..6124
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..6124
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:5315](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..5315)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     aSDomain        complement(12..665)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLV90_RS15730_AMP-binding.2"
                     /evalue="4.90E-67"
                     /label="BLV90_RS15730_AMP-binding.2"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1768"
                     /protein_start="1550"
                     /score="218.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEQAMSRPEAIAVVYEDQQLTYRELNERASQLAHYLQKQGVGSE
                     SLVGLCVDRSPDMVVGLLGILKAGGAYVPLDPTYPEKRLQYIVEDAGIQILVTQAHLQE
                     QEKLQKTVKTIYLDQDQESIARESVLSPKVEVTAQNLAYVIYTSGSTGNPKGVMVEHRN
                     VIRLFQATEPWYQFNEQDTWTLFHSYAFDFSVWELWGALLYGGRLVVVPYWISRS"
     aSModule        complement(12..2069)
                     /domains="nrpspksdomains_BLV90_RS15730_Condensation_LCL.2"
                     /domains="nrpspksdomains_BLV90_RS15730_AMP-binding.2"
                     /incomplete
                     /locus_tags="BLV90_RS15730"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(183..242)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0020"
                     /evalue="3.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1711"
                     /protein_start="1691"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMVEH"
     CDS_motif       complement(438..479)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0019"
                     /evalue="5.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1626"
                     /protein_start="1612"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       complement(1005..1124)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0018"
                     /evalue="2.80E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1437"
                     /protein_start="1397"
                     /score="74.4"
                     /tool="antismash"
                     /translation="RQKALKAYEHQDIPFEKIVEAVQPERSTSHSPIFQTLFTL"
     CDS_motif       complement(1119..1148)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0017"
                     /evalue="9.10E-02"
                     /label="C4_dual_169-182"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1399"
                     /protein_start="1389"
                     /score="6.1"
                     /tool="antismash"
                     /translation="FRDLLAQVRQ"
     aSDomain        complement(1161..2069)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLV90_RS15730_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.10E-113"
                     /label="BLV90_RS15730_Condensation_LCL.2"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1385"
                     /protein_start="1082"
                     /score="368.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="EPVPLSYAQQRLWFIDRFTPNSALYNIPGVWRLKGDWSIEGLEKG
                     LNALIERHEVLRTVIHEVDGQPVQQVPPFMPKELPVINLMHLSFAEREAEMHRLIQEEA
                     ELPFDLAQGPLMRAKCIQIDEKEWMFLCTMHHIISDGWSMGVFLEELLTLYKNVLDESP
                     AEKLPPLPIQYADFAQWQRKWMEEEGLDTQLQYWQEELSGELPVLQWPTNRVRPVEQTY
                     RGAVHQVLLPPYLVEKLKEVSREEGSTLFMTLLAAYQGFLSRYTGQDDILVGSPIANRN
                     HQEIEGLIGFFVNTLVYRADVS"
     CDS_motif       complement(1173..1262)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0016"
                     /evalue="2.70E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1381"
                     /protein_start="1351"
                     /score="55.0"
                     /tool="antismash"
                     /translation="DILVGSPIANRNHQEIEGLIGFFVNTLVYR"
     CDS_motif       complement(1515..1553)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0015"
                     /evalue="1.20E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1267"
                     /protein_start="1254"
                     /score="17.8"
                     /tool="antismash"
                     /translation="QYADFAQWQRKWM"
     CDS_motif       complement(1605..1670)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0014"
                     /evalue="1.30E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1237"
                     /protein_start="1215"
                     /score="40.0"
                     /tool="antismash"
                     /translation="MHHIISDGWSMGVFLEELLTLY"
     CDS_motif       complement(1887..2003)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0013"
                     /evalue="2.60E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1143"
                     /protein_start="1104"
                     /score="45.5"
                     /tool="antismash"
                     /translation="ALYNIPGVWRLKGDWSIEGLEKGLNALIERHEVLRTVIH"
     CDS_motif       complement(2025..2054)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0012"
                     /evalue="5.50E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1097"
                     /protein_start="1087"
                     /score="9.4"
                     /tool="antismash"
                     /translation="SYAQQRLWFI"
     aSDomain        complement(2124..2327)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLV90_RS15730_PCP.1"
                     /evalue="2.80E-26"
                     /label="BLV90_RS15730_PCP.1"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="1064"
                     /protein_start="996"
                     /score="83.5"
                     /tool="antismash"
                     /translation="EELVVSVWEPILGLENIGAQDSFFELGGHSLLATQVASRLQEAFQ
                     IELSIRELFAYPTVEALATRLDE"
     aSModule        complement(2124..5225)
                     /complete
                     /domains="nrpspksdomains_BLV90_RS15730_Condensation_LCL.1"
                     /domains="nrpspksdomains_BLV90_RS15730_AMP-binding.1"
                     /domains="nrpspksdomains_BLV90_RS15730_PCP.1"
                     /locus_tags="BLV90_RS15730"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2610..2675)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0011"
                     /evalue="1.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="902"
                     /protein_start="880"
                     /score="39.3"
                     /tool="antismash"
                     /translation="FLGRIDNQVKIRGFRIELGEIE"
     aSDomain        complement(2640..3836)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLV90_RS15730_AMP-binding.1"
                     /evalue="2.50E-114"
                     /label="BLV90_RS15730_AMP-binding.1"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="892"
                     /protein_start="493"
                     /score="374.0"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEEQAMSRPEAIAVVYEDQELTYRKLNERANQLAHYLQKQGVGAE
                     SLVGLCMDRSPDMIVGLLGILKAGGAYVPLDPTYPLDRLTYMIEHTQIRILLTKDKVAD
                     HIQNGSIKKIDLDEERLYILAENNCNLNHHINSSHLSYVMFTSGSTGKPKGVCIPHRGV
                     VRLVKETDYIHFTSDDTSLQVASISFDAATFEIWGSLLNGGKLVLFPGSSFSLEELGKV
                     IQDSSITIMCLTTSLFHQVVDFNQKALHGVKQLLVGGDVLSAAHVRKVLQSIPGCRVIN
                     GYGPTENTTCTCSYSMTDPDEVSMSIPIGRPIANTSVYILDRNLQPVPVGIPGELYVGG
                     DGLAHGYLYAEQQTAEKFIPHPFSEHPEEKLYKTGDLVRYLPDGNLEFLGRIDNQVKIR
                     "
     CDS_motif       complement(2763..2852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0010"
                     /evalue="2.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="851"
                     /protein_start="821"
                     /score="39.2"
                     /tool="antismash"
                     /translation="PVGIPGELYVGGDGLAHGYLYAEQQTAEKF"
     CDS_motif       complement(3357..3416)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0009"
                     /evalue="2.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="653"
                     /protein_start="633"
                     /score="29.1"
                     /tool="antismash"
                     /translation="SYVMFTSGSTGKPKGVCIPH"
     CDS_motif       complement(3609..3650)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0008"
                     /evalue="5.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="569"
                     /protein_start="555"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       complement(4176..4295)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0007"
                     /evalue="6.50E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="380"
                     /protein_start="340"
                     /score="73.2"
                     /tool="antismash"
                     /translation="RQKALKAYEHQDIPFEKIVEAVQPERSNSHSPIFQTSFTL"
     CDS_motif       complement(4290..4319)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0006"
                     /evalue="6.30E-01"
                     /label="C4_dual_169-182"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="342"
                     /protein_start="332"
                     /score="3.6"
                     /tool="antismash"
                     /translation="FRELLAQVRQ"
     aSDomain        complement(4332..5225)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLV90_RS15730_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.80E-112"
                     /label="BLV90_RS15730_Condensation_LCL.1"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="328"
                     /protein_start="30"
                     /score="365.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="EPSPLSYAQQRLWFMDRFTPNSALYNIPGVWRLRGEWSIESLEKG
                     LNALIERHEVLRTVIREVDGQPVQQIQPFMPRKLPVIHLMDLSIEEREAEMNRLIQEEA
                     ESPFDLAQGPLMRAQCIQVDEKEWMFLCTMHHIISDGWSMGVFLEELLTLYKDEAAELP
                     LLPIQYADFAKWQRKWIEEEGLDTQLQYWQEELSGELPVLQWPTNRVRPVAQTYHGAVH
                     QVHFPLHLVEKLKEVSREEGSTLFMTLLAAYQGFLSRYTGQEDILVGSPIANRNHQEIE
                     GLIGFFVNTLVYRADVS"
     CDS_motif       complement(4344..4433)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0005"
                     /evalue="2.70E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="324"
                     /protein_start="294"
                     /score="55.0"
                     /tool="antismash"
                     /translation="DILVGSPIANRNHQEIEGLIGFFVNTLVYR"
     CDS_motif       complement(4689..4724)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0004"
                     /evalue="1.10E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="209"
                     /protein_start="197"
                     /score="17.8"
                     /tool="antismash"
                     /translation="QYADFAKWQRKW"
     CDS_motif       complement(4761..4826)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0003"
                     /evalue="1.30E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="185"
                     /protein_start="163"
                     /score="40.0"
                     /tool="antismash"
                     /translation="MHHIISDGWSMGVFLEELLTLY"
     CDS_motif       complement(5046..5159)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0002"
                     /evalue="5.70E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="90"
                     /protein_start="52"
                     /score="47.7"
                     /tool="antismash"
                     /translation="ALYNIPGVWRLRGEWSIESLEKGLNALIERHEVLRTVI"
     CDS_motif       complement(5178..5210)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15730_0001"
                     /evalue="4.70E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="BLV90_RS15730"
                     /protein_end="46"
                     /protein_start="35"
                     /score="9.6"
                     /tool="antismash"
                     /translation="SYAQQRLWFMD"
     gene            complement(5312..>6124)
                     /locus_tag="BLV90_RS15735"
                     /old_locus_tag="SAMN05444487_1302"
     CDS             complement(5312..>6124)
                     /NRPS_PKS="Domain: PCP (146-212). E-value: 1.9e-25. Score:
                     80.8. Matches aSDomain: nrpspksdomains_BLV90_RS15735_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503051.1"
                     /locus_tag="BLV90_RS15735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_1302"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_143035085.1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-24, bitscore:
                     72.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-19, bitscore:
                     57.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RFVSHRFGEQVKRLYRTGDLARYLANGDLEYLGRIDHQVKVRGFR
                     IELGEIEAALLTHASVTEAIVMVREDEPGDKRLVAYVIGDGSTAMWREHLKAQLPSYMV
                     PAHFVAIEAFPLTPNGKVDHKALPAPDEQQVGDHYIAPRTSLEELVVSVWEQVLGIENI
                     GVQDSFFELGGHSLLATQVVPRLQEVSQIELPLRELFEHSTVEALAERLNLLSNIGERT
                     SSLQEYIQEQEEVHNDKELSDLLKQLEEMSEEESQELLRNTAEKGVKK"
     aSDomain        complement(5486..5683)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLV90_RS15735_PCP.1"
                     /evalue="1.90E-25"
                     /label="BLV90_RS15735_PCP.1"
                     /locus_tag="BLV90_RS15735"
                     /protein_end="212"
                     /protein_start="146"
                     /score="80.8"
                     /tool="antismash"
                     /translation="EELVVSVWEQVLGIENIGVQDSFFELGGHSLLATQVVPRLQEVSQ
                     IELPLRELFEHSTVEALAERL"
     CDS_motif       complement(5591..5620)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15735_0002"
                     /evalue="1.60E-03"
                     /label="PCP_mC"
                     /locus_tag="BLV90_RS15735"
                     /protein_end="177"
                     /protein_start="167"
                     /score="11.7"
                     /tool="antismash"
                     /translation="SFFELGGHSL"
     CDS_motif       complement(5966..6031)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLV90_RS15735_0001"
                     /evalue="1.80E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="BLV90_RS15735"
                     /protein_end="52"
                     /protein_start="30"
                     /score="42.2"
                     /tool="antismash"
                     /translation="YLGRIDHQVKVRGFRIELGEIE"
ORIGIN
        1 aaatctttcg gagagcggct aatccagtac ggtacgacaa ccaaacgacc gccatacagc
       61 aaggcccccc ataattccca aacggaaaag tcaaacgcat acgaatggaa aagcgtccat
      121 gtatcctgtt cattaaactg ataccagggt tctgtagcct gaaagagtcg gatcacatta
      181 cggtgctcca ccatcacacc cttcggattt cccgtcgaac ctgaggtgta gatgacatac
      241 gccaaattct gagcggtcac ttccacctta ggggaaagaa cactttctcg ggcaatactc
      301 tcttgatcct gatccagata aatggtttta accgtcttct gtaacttttc ttgctcttgt
      361 aagtgtgctt gggtaacgag tatctggata ccagcatcct cgacaatata ttgtagccgt
      421 ttctctggat aagtcggatc aagcggtaca taagctcccc cggcttttaa gatgccgagt
      481 aaccccacaa ccatgtctgg ggaccgatcc acacacaacc ccaccagtga ttcgcttcct
      541 actccctgct tctgaaggta atgcgccagt tgactggcac gttcgttcaa ttcacggtag
      601 gtcagctgtt gatcctcata gaccacggcg atggcttctg gacggctcat ggcttgttct
      661 tcaaatagct catgaatcgt cagagcttga ggataggcta ctgtcgtatc attccattcc
      721 accaacagct gctgcttttc ttcttctgcc atcaggtcca aacttcccag tgctttttct
      781 gaatggtggg ccacttcatg caaccagttt tcaaagtgtc tcgccattct ttcaatggtt
      841 gcccgatcaa ataaatccgt gttgtactca aaggcagccc aaagcccctc cgctttctcc
      901 accatcgcta cagtcagatc aaatttcgcg gttgatacat ggttgtctac caattccatc
      961 tttttaccag gcaagtaggg tagcttccat gacgccgtat cttgtaaggt aaagagcgtc
     1021 tggaaaatcg gagaatgact cgtactccgc tccggttgca ccgcttccac tattttttcg
     1081 aaggggatat cttggtgctc gtacgccttt agtgcctttt gacgcacttg cgctaagagg
     1141 tctcgaaagg tcgggttgcc gcttacatcc gctcgataca cgagagtgtt gacgaaaaat
     1201 ccaatcagcc cctcgatttc ttgatgattg cggttcgcaa ttgggctccc caccaagatg
     1261 tcgtcttgtc cggtatatcg agacaagaat ccttgatagg ccgccagcaa ggtcataaat
     1321 aacgtggacc cttcctcacg acttacctct tttaactttt ctactaagta tggtgggagg
     1381 aggacttgat gcacagcccc gcgataggtt tgttccaccg gacgcacccg gttggtaggc
     1441 cactgcaaga ctggtagttc gccagatagt tcttcttgcc aatattgaag ctgtgtatcc
     1501 agcccctctt cttccatcca cttccgttgc cactgggcaa agtccgcgta ctggatcggc
     1561 aatggaggaa gtttttctgc gggggattca tccagtacgt ttttatacaa ggtgagcagt
     1621 tcctctagga aaacccccat ggaccagcca tctgagatga tgtgatgcat ggtgcacagg
     1681 aacatccact ctttttcatc tatttgaatg catttcgccc gcatcaaggg gccctgagct
     1741 aggtcaaagg gtagctccgc ttcttcctga atgagacgat gcatctccgc ttctctttct
     1801 gcgaaggaaa gatgcatcag gttgatcacc ggcagttcct tgggcataaa aggtggcacc
     1861 tgttgcaccg gttgaccatc cacttcgtga atgactgtgc gtaacacttc atgccgctca
     1921 atcagtgcgt tgagcccctt ttctaggcct tctatagacc aatccccttt taatcgccat
     1981 acccctggaa tgttgtaaag ggcgctattg ggcgtaaacc gatcgatgaa ccacaggcgt
     2041 tgctgcgcat atgagagtgg aaccggttcc gtccgttcca tcggcttcaa tggcggtaac
     2101 gttgccttct ccccttgacg caactcgtcc aatcgtgtcg ctaacgcctc aaccgtggga
     2161 taggcaaata gctcccggat cgatagttca atctgaaacg cttcttgtaa gcgagaagcc
     2221 acttgggtcg ctaataacga gtgcccacct aattcaaaga atgagtcttg cgccccgatg
     2281 ttctcaagtc ccagtatcgg ctcccatact gacaccacga gttcttccaa tggggttcgt
     2341 ggggcgatat actgccctcc cacttgtttg ccgtctggaa tcggtaaggc ttttcggtca
     2401 attttcccat tcgatgtgag tgggaacgcg tccagcacga caaagtaagc aggcaccatg
     2461 taactgggca attgatcgga tagatgggct ttccattccg caacgcttcc ttctcccaca
     2521 acataagcga ctaaccgttt atccccgcga tcatattcct gtaccattac cacagattcc
     2581 tggatagaag aaatctcatt taaagcccct tcgatttctc cgagttcaat ccgaaaacca
     2641 cgaatcttga cctgattgtc aatccgcccc aaaaactcca agtttccatc cggcagatac
     2701 cttacaagat cgccagtttt ataaagtttt tcttctggat gttcggagaa agggtgaggg
     2761 ataaactttt cagctgtctg ttgttccgca tataaatatc catgagccaa tccatcccca
     2821 ccaacgtata attcaccagg aatgcccaca ggaacaggtt gtaaattcct gtccaatata
     2881 taaacagagg tgttggcaat cggacgcccg atcgggatag acatcgacac ctcatctgga
     2941 tcggtcattg aatagctaca ggtacaagtc gtgttttctg ttggaccata tccattaatg
     3001 actcgacatc ccggaattga ctgcaacact ttacgtacat gtgcagctga aagcacatca
     3061 ccaccaacta agagttgctt cacaccatgc aatgctttct gattaaagtc taccacttgg
     3121 tgaaataaac tagtggtcag acacattatc gtaatactag agtcttgaat cactttacct
     3181 agttcttcta aggagaagct actccctgga aataaaacta gttttccccc atttaagaga
     3241 cttccccaaa tttcaaaggt agccgcatca aaagatatag aggcaacttg aagagaggta
     3301 tcatctgaag tgaaatggat ataatccgtt tccttcacta gccttactac tccacgatga
     3361 ggaatacaaa ccccttttgg tttaccagta gaccccgaag taaacataac ataactaaga
     3421 tgtgaagaat ttatatgatg atttaagtta caattgtttt ccgctagaat atataatcgt
     3481 tcttcatcta aatcaatctt tttaattgaa ccattctgaa tgtggtcggc cactttatct
     3541 ttcgttaata atatacggat ctgtgtatgc tcaatcatat aggtgagacg atcgagggga
     3601 taagtcgggt ccagtggtac ataagctccc ccggctttta agattccaag taaccccaca
     3661 atcatatctg gcgatcgatc catacaaagt cccaccagtg attcggctcc tacaccttgc
     3721 ttctgaaggt agtgcgccag ctggttggca cgttcgttta atttacggta ggtcaactct
     3781 tgatcctcat agaccacggc aatggcttct ggacggctca tggcttgttc ttcaaatagc
     3841 tcatgaaccg tcagggctcg aggatagact actgtcgtgt cattccaatc caccagcagt
     3901 tgctgcttct cctcttctgc catcaggttc aaacttccca gtgttttgtc agaatgataa
     3961 gctacttcat ttaaccagtt ttcaaagtgc cgcgccattc gctcaatggt tgccccatca
     4021 aataaatcgg tgttgtactc aaaagcaatc caaagcccct ccgctttctc ctccatcacc
     4081 acggtcagat caaatttcgc gacagatgta tgaatgtcta caggctccat agttttccca
     4141 gacaagtctc ttgacttccg tgacgctgta tcttgtaagg taaagctggt ctgaaaaatc
     4201 ggggaatgac tgttgctacg ctctggctgc accgcttcca ctattttttc gaaggggata
     4261 tcttggtgct cgtacgcctt tagcgccttt tgccgcacct gggctaagag ttctcgaaag
     4321 gtcgggtttc cgcttacatc cgctcgatac acgagggtgt tgacgaaaaa tccaatcagc
     4381 ccctcgattt cttgatgatt gcggttcgca atcgggctac cgactaagat gtcttcttgt
     4441 ccggtatatc gagacaagaa tccttgatag gccgccagca aggtcataaa taacgtggac
     4501 ccttcctcac gactaacctc ttttaacttt tctactaaat gaagtgggaa gtgaacttga
     4561 tgcacagcgc catgataggt ttgtgccacc ggacgcaccc gattggtagg ccactgcaag
     4621 actggtagtt cgccagatag ttcttcttgc caatattgaa gctgtgtatc tagcccctct
     4681 tcctctatcc acttccgctg ccacttggca aagtctgcat actggatcgg caatagagga
     4741 agttctgctg cttcgtcttt atataaggtg agcagttcct ctaggaaaac ccccatggac
     4801 cagccgtctg agatgatgtg atgcatggtg cacaggaaca tccactcttt ttcatctact
     4861 tgaatgcatt gggcccgcat caagggaccc tgagccaagt caaaggggga ttccgcttct
     4921 tcttgaatga gacggttcat ctcggcttct ctttcttcga tagacagatc cattaagtgg
     4981 atcaccggca gcttccttgg cataaaaggt tggatctgtt gcaccggctg accatccact
     5041 tcacgaatga ccgtgcgtaa cacttcgtgc cgctcaatca gtgcgttgag ccccttttcc
     5101 agactttcta tagaccattc ccctcttaat cgccataccc ctggaatgtt gtaaagggcg
     5161 ctattgggcg taaaccgatc cataaaccat aaacgttgtt gcgcgtaaga aagtgggctg
     5221 ggttctcttt ttttattttt gtgcagctgt ttctctagca gcattctctt ttccggagaa
     5281 agagtggaaa gtctttctat taaattatta ttcatttctt tacacctttc tcagctgtat
     5341 ttctcaacaa ctcctgcgac tcttcctctg acatttcttc taattgtttg agtagatcag
     5401 acaattcttt atcattatga acttcttcct gctcctgaat atattcttgg agactagatg
     5461 tccgctcacc aatgtttgaa agtaggttta atctctccgc caaagcttcg actgtagaat
     5521 gctcaaacaa ttcacgtagg ggaagctcga tctgggatac ttcttgtaat cgaggaacca
     5581 cttgagtggc taataacgag tgtccaccta attcaaagaa agagtcctga actcctatgt
     5641 tctctatccc tagcacttgt tcccataccg aaaccactag ctcctctaat gaggtacgag
     5701 gggcaatgta atgatcccca acttgctgtt catcgggggc aggtagcgct ttatgatcca
     5761 cttttccatt cggggtaagg ggaaaggctt ctatggcaac aaaatgtgca ggaaccatgt
     5821 agctcggtaa ttgcgctttg agatgctccc gccacatggc agtacttcca tcaccgataa
     5881 cataggccac cagtcgtttg tcccccggct cgtcttcccg caccatgacg atggcttcag
     5941 taacggaagc atgtgtaagg agggccgctt cgatttctcc gagttcaatc cggaaaccac
     6001 gcacttttac ttgatggtcg atcctcccca gatactctaa atccccattg gcaaggtacc
     6061 ttgccaaatc ccctgtccgg tataatcgct tcacctgctc tccaaaacga tgggagacga
     6121 aacg
//
