LOCUS       NZ_FNNQ01000013        26336 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Marininema mesophilum strain DSM 45610, whole genome shotgun
            sequence.
ACCESSION   NZ_FNNQ01000013
VERSION     NZ_FNNQ01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Marininema mesophilum
  ORGANISM  Marininema mesophilum
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Marininema.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900106775.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:02:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,196
            CDSs (total)                      :: 3,130
            Genes (coding)                    :: 3,066
            CDSs (with protein)               :: 3,066
            Genes (RNA)                       :: 66
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (5S, 16S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 21 of 64
            Pseudo Genes (incomplete)         :: 50 of 64
            Pseudo Genes (internal stop)      :: 5 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 72574
            Orig. end                         :: 98910
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNNQ01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26336
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26336
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26336
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16336](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16336
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(73..86)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     misc_feature    485..505
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.96"
                     /tool="antismash"
     gene            1163..2449
                     /locus_tag="BLV90_RS12620"
                     /old_locus_tag="SAMN05444487_11379"
     CDS             1163..2449
                     /EC_number="6.3.4.4"
                     /GO_function="GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011232939.1"
                     /locus_tag="BLV90_RS12620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11379"
                     /product="adenylosuccinate synthase"
                     /protein_id="WP_091741634.1"
                     /transl_table=11
                     /translation="MSTVVVVGTQWGDEGKGKITDYLAEKAEVVSRYQGGNNAGHTIEF
                     GGKRYKLHLIPSGIFYLEKVCVLGNGMVLHPEAMLEELEYLRTHGFSSQNLRISDRAHV
                     IMPYHIRLDKAEENRKGKSKIGTTGKGIGPAYMDKAARTGIRISDLLDRDLFAKKLQKT
                     IEEKNRILEKLYDTKGFTFEEIYEPYVEAADQLRPYVTDTSVVLNDAIDQGQRVLFEGA
                     QGVMLDIDQGTYPFVTSSNPVAGGVCIGSGVGPTKIHQVIGVAKAYTTRVGDGPFPTEL
                     KDEVGKKIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGITGLSLNSIDVLTGLDTV
                     KICTAYRYRGRVLENYPANLDVLSECEPVFEELPGWQEDITGVRNLSDLPMAAQHYVER
                     ITHLTGIPLTIFSVGPGREQTIQVRPAYA"
     gene            complement(2618..3097)
                     /gene="rlmH"
                     /locus_tag="BLV90_RS12625"
                     /old_locus_tag="SAMN05444487_11380"
     CDS             complement(2618..3097)
                     /EC_number="2.1.1.177"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rlmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019720229.1"
                     /locus_tag="BLV90_RS12625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11380"
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="WP_091741637.1"
                     /transl_table=11
                     /translation="MRIQLITVGKIKEKYLRMGVEDYIQRITPYAKVEVTEITEEKGQE
                     PLSPAEIEQLVTKEGERILRALSSDTYAMALAIQGVAFSSETLANHLNQLATYGRSKVA
                     FIIGGSYGLSKAVLQRADYSLSFSKMTFPHQLMRMLLLEQVYRSFKINRGETYHK"
     gene            complement(3136..3336)
                     /locus_tag="BLV90_RS12630"
                     /old_locus_tag="SAMN05444487_11381"
     CDS             complement(3136..3336)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04129.1"
                     /locus_tag="BLV90_RS12630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11381"
                     /product="CxxH/CxxC protein"
                     /protein_id="WP_091741641.1"
                     /transl_table=11
                     /translation="MAGTDQIYIKWYACDEHVEVVLDQLVDEVEIAPDLNPCEPDEAKT
                     ATCHWCGGTPAYRLSAHPSNP"
     misc_feature    3331..3341
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            3817..4722
                     /locus_tag="BLV90_RS12635"
                     /old_locus_tag="SAMN05444487_11382"
     CDS             3817..4722
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009675873.1"
                     /locus_tag="BLV90_RS12635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11382"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_342707326.1"
                     /transl_table=11
                     /translation="MIIQTERLTKKYGGHASVNNVNLQVAKGEVYGFLGPNGAGKTTTI
                     KMLLGLAKPTKGSVTIFGRDIQEDRKNILRQVGSLVESPTYYGHLSGRDNLKVIAQVLG
                     LPKKNIEEALQMVRLTKDADRLVKGYSLGMKQRLGIAVALLAKPQLLILDEPTNGLDPA
                     GIREIRELISRLPEEQGVTILISSHLLSEIEQVATSVGIIFRGQLIFQDSLEVLKQRAK
                     GRIELEVSRPTEAKNYLESLGWQPFIDEERVCFTPMAREKVADVVENLVRGDFSVYGMN
                     KISQSLENIFIELTGKEQSL"
     gene            4719..5429
                     /locus_tag="BLV90_RS12640"
                     /old_locus_tag="SAMN05444487_11383"
     CDS             4719..5429
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="BLV90_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11383"
                     /product="ABC transporter permease"
                     /protein_id="WP_091741647.1"
                     /transl_table=11
                     /translation="MMGLLLSDARKIKGTWIPWLLLVAPIGFSLLQVVNYMTRPEILKP
                     LGWVGLMAQANYFWPVVLILGFAIATSMVAGMEHDASSWKVIFSLPINKFSTYVSKFFL
                     LLIYIIGFVFLTLIGLLLVGLLFSLGPIKWSLVLEQLFYPCLAGIPVLALQLWISMIFH
                     NQALSITVGIIGAMLCLFLAYSSVKLFNILPWAYIPLASPLNKGEYMQWPLFGVIIGVF
                     LLIIGGIHFSKREL"
     gene            5451..6188
                     /locus_tag="BLV90_RS12645"
                     /old_locus_tag="SAMN05444487_11384"
     CDS             5451..6188
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="BLV90_RS12645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11384"
                     /product="ABC transporter permease"
                     /protein_id="WP_091741650.1"
                     /transl_table=11
                     /translation="MESLVSLRYLRSEFYKIRWSMIIGILLLGPAISLWIGFGNPTEMS
                     EGANDWLWFFSLTVHKYTMFFYPLIVGVFAAFVCRYEHLANGWKQIFCLPVSRFQIYSS
                     KFLLVSLLTLLTQLCLLSGFLIVGTIYGLNDPLPWSILITKVIKGWLASLPLMALMLGC
                     SLLWKNFATPLTLNVVFILPSMIMTGSGLLGSWYPWSQPFLAMMPKHEWVTSINPFMLF
                     MGILSTFILFVVSTSTIFIKRDY"
     gene            6240..6941
                     /locus_tag="BLV90_RS12650"
                     /old_locus_tag="SAMN05444487_11385"
     CDS             6240..6941
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012698.4"
                     /locus_tag="BLV90_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11385"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_091741653.1"
                     /transl_table=11
                     /translation="MKSVLLISDNPIMVKLVIENTMKSDIKIDLQSPGTLTPDFLQENN
                     PYSAVLIDTSSRDTSFLLALIPLSQKYGVPIILLNGGQDHTDVVSELIKDLYRGSVIST
                     APIDNEQEKIPINRNVIFDLKNHIIINRDVEISLPNIEYRLLKTLCERSPDYLSTEELL
                     DVVWGEDKFVNVDTVYVHIRRLRKKIEANPGNPKNLINQKGVGYRIHSLFDPGEYSMYD
                     LEKSVAVNGLN"
     gene            6945..7670
                     /locus_tag="BLV90_RS12655"
                     /old_locus_tag="SAMN05444487_11386"
     CDS             6945..7670
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370161.1"
                     /locus_tag="BLV90_RS12655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11386"
                     /product="response regulator transcription factor"
                     /protein_id="WP_342707324.1"
                     /transl_table=11
                     /translation="MILLDHTNLLLVDDEPEILQLLTKTLHSEGFQRIFTAGTGHEAIQ
                     ICAKHQPDVILLDVMLPDMEGYEVCKKLREITHSPIFFLTARTTDLDKLMGYNMGADDY
                     IEKPFNPLIIVAKIKAQLKRDQLSQTAEDIFPQPYDFGDFKLVENTGQLFVKGEEISCT
                     AKEFKLLAFLCKHPHQIFSMGQLYRQVWGEESFGYENTVMVHIGKIRKKIEPDVRKPKY
                     IVTIRGLGYKFIGNLVGSQ"
     gene            7667..9421
                     /locus_tag="BLV90_RS12660"
                     /old_locus_tag="SAMN05444487_11387"
     CDS             7667..9421
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="BLV90_RS12660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11387"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_091741659.1"
                     /transl_table=11
                     /translation="MKLENRLMVKFLTGVVTLSLILIGLFLFFYYGAGMLKGGKQQPSN
                     DPEAVMGRMASEATVSNDGRVEISSKMKEQLSRNQEWTQVLNGRGQEVMRYRAPKNVPV
                     NYSPSDLVQLKKEMRRKGYNIHVWNKNHEKEEYTWILGRKNNYVLLRTLKDATQWKDGK
                     IYVPTSLLRQVHKQRGWVQILDEKGREIYEFERPKDTVKNYTPGKFVYMDSSSLIYLTG
                     KLNGKPVTWVYNHASEVNDQEKKTNLTIAALFFTSIIASLCVFVFFAYRFGRKLGEPLL
                     LILRWIQDLSRGDYRGCIRAKYVRDPQTGQLKKRFRIYQEVMEALEKLSVQLNEVEEKR
                     SRLDQSRDEWLAGVSHDLKTPLSTIKGYADLYAHREYRWSTAEMEHYLELVIQKTEYIQ
                     HLIEDMNITFQMKNEALSLNRERGDMKETLRMIVAEVLSEADVEESHIRLELPKDTHVM
                     ASVDPKWFKRAVINILTNAFVHNPPDTEVIVELKVETNVAPSSVDPGLRISIRDDGVGM
                     DAKTVSTLFQRYYRGRSSINSSYGTGLGMAIAKKLIELHDGEISVRSHLNKGTEMTIEL
                     PSREIPAS"
     misc_feature    9482..9491
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(9489..9502)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.51"
                     /tool="antismash"
     misc_feature    9491..9504
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.03"
                     /tool="antismash"
     gene            9720..9845
                     /locus_tag="BLV90_RS16000"
                     /old_locus_tag="SAMN05444487_11388"
     CDS             9720..9845
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="BLV90_RS16000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11388"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_143035056.1"
                     /sec_met_domain="TIGR03731 (E-value: 1.5e-09, bitscore:
                     30.7, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANPFDLDLQSVEVKQGDVQAGSGLICTPGCDEGTFESWCC"
     misc_feature    complement(9897..9913)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.49"
                     /tool="antismash"
     misc_feature    9919..9933
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     misc_feature    complement(9966..9980)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            10001..13111
                     /locus_tag="BLV90_RS12665"
                     /old_locus_tag="SAMN05444487_11389"
     CDS             10001..13111
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="BLV90_RS12665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11389"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_177168050.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 9.7e-188,
                     bitscore: 618.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.2e-16,
                     bitscore: 54.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1e-35, bitscore:
                     116.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYEPINAWMLRTPTWPIEKFNALTTDKTMPFQQLLLKTMDKTFIE
                     SIAIASPSLYEDLSQLEGDSHQRKTKQVVASVLKYATRMSTRPTPFGLFAGVTVGELSE
                     GTTISLQSSENHIKRARPDMEWLLTLIEKLEEDIEGIQQIKVYKNQLVTKSGGRLYLPY
                     QTGYGRQTNITSKKERVSIQLNEAALQVLKASREPIVLSELIARISSYYSNFDPVQIRT
                     YILQLLKQEFLISELRPPLTISNPFHYIINQIKDIPRYHDVYLQLVEIDQLLEDFNASP
                     MGEGIEIYLDVIQKMKSINETKAYLQVDLGLKNRELTLNQAVADEAAKAATILWRISQT
                     EKGLPHLKKYRDRFLDRYGRDREVPILELLSEESGLGSPEEYYPDAPSTISEPRNSERE
                     QRLLEMMQTALLNRQYVVQLDAKALKDIIPPSVDDRDAPSTVELYTEVLAKSAKAVDDG
                     EFTLVIAPNPGSGSAGQTFGRFFDVLDPFTKNKLQAAHKEINDAQPDVITADCVYFPTR
                     GRAANVSLAPGLQEYELVLGTNYASDKKKLFLEDIVVGATLERLYFKSVSLGKEVTFTA
                     NNMLNFQSSPGVYRFLREVSLENVRIWHSYEWGTLRDSPFLPRVQVDKTILSPAKWKLS
                     MGQLELKKEASVEEWNTAFDHWLKKWMVPRFVYMGATDQRLLLDLEHPAHRKEIIKAVE
                     NKGRVHLSESFYQQNNDWIVDADHHHYIGEFVFPLKKREALPHPSPVTPVMKKLASNSR
                     IKLPGSDCLYIKVYMAKSRQNDFISRPLSHFVKNAREEGLVQRWFFMRYGDPDNHLRIR
                     FFGEPERLIASLIPTIHTWAERLVEEGLIQKLTIDAYDPEFERYGGPQLIHHAERVFEA
                     DSDLVAYLVNQIRFGKIEFPEEFVASMNMLDFMEQYGLNFEDRLLWLDQMVQPDEHRKE
                     FQLWRRAIVECTLHNPVWAQLLGVDQEIIKGLADKRNQGITEFKSQMERIQEQNLLWNH
                     PHKILGSMLHMTCNRLMGDNSKEMKARAFARHALYSQQYLRKQLVST"
     aSDomain        10442..10720
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BLV90_RS12665_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.80E-17"
                     /identifier="RREFam001.1"
                     /label="BLV90_RS12665"
                     /locus_tag="BLV90_RS12665"
                     /protein_end="240"
                     /protein_start="147"
                     /score="54.2"
                     /tool="antismash"
                     /translation="KNQLVTKSGGRLYLPYQTGYGRQTNITSKKERVSIQLNEAALQVL
                     KASREPIVLSELIARISSYYSNFDPVQIRTYILQLLKQEFLISELRPP"
     gene            13129..14970
                     /locus_tag="BLV90_RS12670"
                     /old_locus_tag="SAMN05444487_11390"
     CDS             13129..14970
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="BLV90_RS12670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11390"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_091741665.1"
                     /transl_table=11
                     /translation="MNRDNQLENVSIYNFVKLASYIKRIFTILWSVHPLQFVSIIVLTI
                     LQGVAPTFFILASQFAINQLVSSWGSGFHIVINAMLVLGGVMVFNELCNILRVYVDRIF
                     EVSLSYQVDLLVMQKASTLHLSDFEDHEVQDQIKRVQNESNIRVYQVFKQVMTVLSGGV
                     TLVSSALVLFAWHWWAAVLILGVPIIFFPLLLKLGEKEFKYLWKRAPKTRELWYINYIM
                     TRDLSFKEVKLYQLGPYLIDQYQKIHRSFIAEDKEIALQRRNLSFLYYGINYTAVMIVI
                     HFIFKAAYMKQLMIGNVVGYLQAINLTLSTARNLTQEVMLLFQNNLFLEQLFTYLDMKV
                     ESPAELIEGKKHLQSPITQLELRNLSFQYPNTDKPVLKGINLQLHAGETLAIVGPNGSG
                     KSTLIKILTQMYNQFTGEYLINRTSIRKYDSDEVNRRIGGVFQDFVQYEMPLRHNIGFG
                     DVEKIDDDLALMKAAEKGGLSSLVHSLPKKLDTQLGKLFKDGHQLSGGQWQRVAIARAY
                     LRDADICLFDEPSSFLDPQAEHEVFEKFKDLVRDRIGIFITHRLSSVRYADRIIVMDQG
                     QIVEMGSHDQLINLNGLYKDMFTKQAESYLDAKISSA"
     gene            14984..16336
                     /locus_tag="BLV90_RS12675"
                     /old_locus_tag="SAMN05444487_11391"
     CDS             14984..16336
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="BLV90_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11391"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_177168051.1"
                     /sec_met_domain="LANC_like (E-value: 2.3e-74, bitscore:
                     243.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKVIHRRRVRSAIADKGLEISQRIAERLVDPIQIKEIVERPDN
                     VSVMGATPWGDTSLSHGYPATVLFFSQWDRYEPDQKWDYKGHAHIVEMQRALESNGIGS
                     ISLFGGLTGVAFACQAASREGERYGNFLKVIHSKIAQETKRFIEGDNTRRKSEVGLSPK
                     VYDVISGLSGIGRYALNHPHHDELNDVLEQTLHHLVEVSHDIEVDHHTVPGWYIPQQYQ
                     FMEREKELFPKGNFNCGLAHGIPGPLVLLSLASLRGYRVDGQLEAIQRMSDWLVKRAYQ
                     DRYGVLWSDRIRFEEEVSRKPSQKYFSREAWCYGAPGVARSLYLAGMALGDEELKKLAI
                     QAVKSSFMRPEELSKLESATFCHGKSGILQILLRMAKDTGEEIFVKHAELMAKEIIDMF
                     QGESPFGYQDLEGGRGLNKAGLLEGVSGIGLSLMSLSEKQDADWDAAFLIS"
     gene            16351..16935
                     /locus_tag="BLV90_RS12680"
                     /old_locus_tag="SAMN05444487_11392"
     CDS             16351..16935
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014494.4"
                     /locus_tag="BLV90_RS12680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11392"
                     /product="flavoprotein"
                     /protein_id="WP_091741671.1"
                     /sec_met_domain="Flavoprotein (E-value: 4.1e-30, bitscore:
                     97.2, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTDQLKIKNLLVGIGGSISVLAVPSYLTLFAHFFKEVKVIMTPS
                     AARLLPRETVNLLCAGAYTDEQEFSQEISHVELTRWADGLVILPATANTMGQAANGLGD
                     NLLTTAILAYPEPIIYFPNMNERMWRKKSLQRNIKTLEADGDIVVEPSHQMAYEVASGK
                     MRPNYTIPSKENVMKVIYKQLVGNVQTVSKS"
     gene            16969..17571
                     /locus_tag="BLV90_RS12685"
                     /old_locus_tag="SAMN05444487_11393"
     CDS             16969..17571
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009711516.1"
                     /locus_tag="BLV90_RS12685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11393"
                     /product="nitroreductase family protein"
                     /protein_id="WP_177168052.1"
                     /sec_met_domain="PF00881 (E-value: 2.2e-30, bitscore: 98.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMSVKQAMETRCSIRTYLQEPVPREDIEEIIRLTRLAPSAWNIQ
                     PWRFIVVTNKETKQELYNIANKHPQVESAPVAIVVTSDMEDAIANLEEFIHPSMPEDAR
                     AWLTNTIPKIFGEQTIEQRGQWGVAQSNIALGYLLIAIRSLGYDSSPMYGFNPYKVREL
                     FELSDHVQIPSIVTLGRRGEEGREHHRHSLDKLIRYV"
     gene            complement(<17678..17797)
                     /locus_tag="BLV90_RS12690"
                     /old_locus_tag="SAMN05444487_11394"
                     /pseudo=""
     CDS             complement(<17678..17797)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012371880.1"
                     /locus_tag="BLV90_RS12690"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11394"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHKAFKFRLYPTKEQTILIHKSMGCSRFTFNHFLARWNES"
     misc_feature    17946..17960
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.29"
                     /tool="antismash"
     misc_feature    18012..18021
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    18013..18026
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     misc_feature    complement(18014..18027)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.86"
                     /tool="antismash"
     misc_feature    complement(18015..18028)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     gene            18282..19229
                     /locus_tag="BLV90_RS12695"
                     /old_locus_tag="SAMN05444487_11395"
     CDS             18282..19229
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012318.4"
                     /locus_tag="BLV90_RS12695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11395"
                     /product="serine protease"
                     /protein_id="WP_091741677.1"
                     /transl_table=11
                     /translation="MINRKRGLRIPLLGLVVAVSLSLPLIGLSSAEAAPSKSKLSPDTM
                     ISNDGTITAPTAPFSNEFSKQRDGGATTSSYKGNGEALAKQTSIVTKKDTVKNDPPFIG
                     VKSIIGSDGRIRVNPTTSFPYSAIAQISSDIGDCTGWFISADTIITAGHCVYNTGNNKW
                     ASWATITPGRDGNNAPYGTYSAKSFHSVLGWVTNEDTNYDYAAIKINSDIGYTTGWFGL
                     RLQPGSLTGTAETISGYPRDKAYGTQWRHSDQIRQTYDRKLYYGNDTYGQSGSPVYTND
                     YYSVAIHTNGGNPYNNGTRINENVFNNLLYWRDH"
     gene            complement(19334..20488)
                     /locus_tag="BLV90_RS12700"
                     /old_locus_tag="SAMN05444487_11396"
     CDS             complement(19334..20488)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009708921.1"
                     /locus_tag="BLV90_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11396"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_091741679.1"
                     /transl_table=11
                     /translation="MGFYNDRNRSTKSLIWVALISAIVGGLLVLIVSPALVRSGILPQQ
                     SFQGPAVSENTGPASSVNVTSNITKAVEKVRPAVVGIVNQKSSDPFTQKTVEQGTGSGV
                     IFKKQGGKALVVTNQHVVAGADKVSVVIPGEGQGKEVSARVIGKDEPTDLAVLEMSSEY
                     VKAVAQFGNSDKLKAGEPAIAIGNPLGLEFSQSVTSGVISSPHRQIAVSENMAMDAIQT
                     DAAINPGNSGGALVNVAGQVIGINSLKIAEQGVEGLGFAIPSNDAKPTINDLVQYGKVK
                     RPFLGIQLRDLDTITNDDRQRLNLPDSVRNGVAIINVTNGSSADEANLQRLDVITALDG
                     KPIKNGSALRSYLWKEKEVGETTTFTFYRDGKKMTAKVKLREKS"
     gene            20686..20877
                     /locus_tag="BLV90_RS12705"
                     /old_locus_tag="SAMN05444487_11397"
     CDS             20686..20877
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV90_RS12705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444487_11397"
                     /product="hypothetical protein"
                     /protein_id="WP_091741682.1"
                     /transl_table=11
                     /translation="MSSNKRTEPIDPWTLVNWGAQLADLKEADHRTRLWLGTLIQVMID
                     NKLVSIEELEKRMAELDG"
     gene            complement(21086..21886)
                     /locus_tag="BLV90_RS12710"
                     /old_locus_tag="SAMN05444487_11398"
     CDS             complement(21086..21886)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007720212.1"
                     /locus_tag="BLV90_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11398"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_091741685.1"
                     /transl_table=11
                     /translation="MKYSILASGSTGNSLYIETENIRILIDAGLSGKQLETKMKAIGAD
                     PTQLDALLVTHEHIDHVKGLGVFARRYQLPIYMNEATWGSLPSGVGAIHPDQQRIFPVL
                     STLQLKDLAIESFPISHDAAQPMGFCFHAEDVSLGLVTDTGYINQRIVEKIRGAEALIL
                     ESNHDVEMLRMGAYPWNIKRRILSDVGHLSNEDAAEALLDILQGEGEDVHLAHLSQDNN
                     LTELAHLTVRSILEEEGLKVGKDIHLRETWPDRPTPLRKIRKRS"
     gene            complement(21907..22653)
                     /gene="yycI"
                     /locus_tag="BLV90_RS12715"
                     /old_locus_tag="SAMN05444487_11399"
     CDS             complement(21907..22653)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="yycI"
                     /inference="COORDINATES: protein motif:HMM:NF021186.4"
                     /locus_tag="BLV90_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_11399"
                     /product="two-component system regulatory protein YycI"
                     /protein_id="WP_091741688.1"
                     /transl_table=11
                     /translation="MEWSKAKSILIMAFLALNIFLASQLFNARTEQSQDDQATNTQEEL
                     NEIATEADITILGKTPAEPPQVNSLKGSPVSFKEPWTNDTDGTWVQTFDPPLTVSGDRE
                     KTLNRYIDSLDNYVFQPDESNDKRQVYYQRYGKNLIFDGKIEAKWKNKNHLTSLRQSLF
                     KVESQNGAKRPGVAATTTLINLIEKGQIQKKETVTNIQLGYHSQSYDKKVRILQPMWRI
                     QTKKHTFFVNAFNGAIESSVNETNHE"
     gene            complement(22660..24009)
                     /gene="yycH"
                     /locus_tag="BLV90_RS12720"
                     /old_locus_tag="SAMN05444487_113100"
     CDS             complement(22660..24009)
                     /codon_start=1
                     /gene="yycH"
                     /inference="COORDINATES: protein motif:HMM:NF019079.4"
                     /locus_tag="BLV90_RS12720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_113100"
                     /product="two-component system activity regulator YycH"
                     /protein_id="WP_177168053.1"
                     /transl_table=11
                     /translation="MIDHIKSVLLTILILTSFVQSGILLYTSPSYEQVLTPDDYSYPHK
                     IVKESFEKQGVHEIAAPSQILIHQNGKHQQIPGNLEKSQIRNLLSNVHLTELTRPQKVT
                     PSNKDWNNLMAKKDGIELRFNNNLSPEIMQAFFTTDLPKPDLRSVSRVWIYQNAAGDQS
                     ARFISDETGKTVQYKATLESFADLIKVADKLNAPFLSATLPKKNSGAIPRPLYLPNDPL
                     AVQQLRYPLKKITINDLKLALFPDPNLIEKKLTLDRATMYTDTTRTLQHNTAKNLITYN
                     RPDSTTESEFSLTDQLDLIQQFMRRHEGWTGNFLLDDIENDPDQVTPFFRFRLYTNGLP
                     VFWDGGEKITPATLRLSAVGKGVTSYDRSLFYPALQPDKKATKVSYLPDKKELLAELDR
                     KGISLEKKVTSIYPGYRTDIKDQAVTFIPTWIIQLEDGTRNYVEKRSPGR"
     gene            complement(24006..25835)
                     /locus_tag="BLV90_RS12725"
                     /old_locus_tag="SAMN05444487_113101"
     CDS             complement(24006..25835)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="BLV90_RS12725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_113101"
                     /product="ATP-binding protein"
                     /protein_id="WP_091741695.1"
                     /transl_table=11
                     /translation="MKFFKWLRLFNSVQWKMVLIYISLLLIAIQLIGVYFFQELEDFYV
                     GDLEVRLKRQADLLISPGGMAKELAKPQLNSAEKRKRLNKLLQNIYILDKGSGQIVQLL
                     DQDGVVLSTTAENKSKIGQKNPRVTSVLRGVNTNDTQFRRGPNNQPLILYSKAITENDQ
                     VIGAIYIEAPMKKTYDTIRTINNKLLQISLFSLVGTAILGIILARTITNPVKEITEQAS
                     EMALGDFHRKVAVKSNDEIGQLAAAFNHLAQHLREALSQNEEEKGKLESVLTNMNDGVI
                     ATDDRGCVIVINQRAGNILGRTIAKGDPITQALPLSEPLPFPLVEERQAYLELNREDED
                     EPTVVKITFTPIRRSEETVGLITVLQDVTEENKLDRQRKEFVANVSHELRTPLTTIKSY
                     LEALDEGGAMEDPELAKRFLRVTRQESERMTRLIHDLLQLSRLDAQKVRFNRQPVAIEE
                     ILSDAVERFSISAEQKNIDISFRFNDHLPKIYGDRDQLDQVLDNLISNAVKYTPEERSI
                     TVSARRRSDGFVVVAVSDRGIGIPQKDLALIFERFYRVDKARSRNMGGTGLGLAIAREI
                     IEAHGGSIDIDSRYGWGTTVHFTLPPYVPEVIR"
     misc_feature    25911..25926
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.36"
                     /tool="antismash"
ORIGIN
        1 ggaaacccgt cgctatcttt aacttggaga tgtcagcccc tcagttggta caacggatgc
       61 ttgcctgtga aggcaatatt gatgcccagg tctttcgtac cggccaactg aaggaagaag
      121 actgggaaaa gctaaccatg gcgatcagta gccttgcgga agccccgatc tttatcgatg
      181 ataccccagg gatcaatgtc tttgacatcc gggcgaagtt acgtcgcctc caggcggaac
      241 atggtttagg gatggtgatg atcgactatc tccagttgat tgaaggacga ggaaaagata
      301 gccgccaaca ggagatttct gagatttccc gttctctgaa actattggca cgggagttaa
      361 actgtccagt catcgcgtta tcccagcttt ctcgtgcggt agagcaaaga caggataagc
      421 gtccgatgtt atcggacttg cgggaatccg gctcgattga gcaagatgca gatattgtat
      481 cttttcttta tcgggatgac tattacaacg aggagtcaga gaagaagaat attacagaag
      541 tgattctagc caaacaccgg aacggtccgg taggtaaagt agaactactc ttcctgaaaa
      601 actacaataa attcctcagc ctggacttgc gtcatggtca ggcaatgggt ggataatcag
      661 tgcgaaacct ccttacttaa tcgacagctc tggagtctgt ggatgagtaa ggaggtttta
      721 tgtagtcatt tgtttgcaag ggttaatata aacagctggg tggttaccca actgtcgaag
      781 catcacaatg ttggcttagg ccggtcgcat atgaatgact aacgctcccc aactaatcta
      841 ggccgtatca ttttacgcta gaccaagggt ttgctaaata tggacattcg ttctgcaacg
      901 aatttccata tttttatgga gggacaaaag gcctaagcag ggtaaatcct gcgggagcct
      961 ttgcatacgc tagattataa gggaaaagtt taatttaatt aggcaatact agaggagcga
     1021 aaaggagata catataaatc cgaacaataa aaagatagat tgattttatc gttcggattt
     1081 ttcgttgaca tctccctctt tccccgttag actgtaaaag gatgaatgac cgcgaacacc
     1141 tgccgcgaag gaggaatgaa ggatgtcgac agtcgtcgtt gtcggaactc agtggggcga
     1201 tgagggtaaa gggaaaatta cggattattt ggcggagaaa gcggaggttg tttctcgcta
     1261 ccaaggggga aataacgcag gacacaccat tgaatttggt ggaaagcgat ataagcttca
     1321 tctcattccc tcaggaatct tctatctgga gaaggtttgt gttttgggga acgggatggt
     1381 gctccatcca gaagcgatgc tggaggagct ggagtatcta cggacgcatg gattctccag
     1441 ccaaaacctg cgcatctccg accgagccca tgtgatcatg ccctaccata ttcgtttgga
     1501 taaggcagag gagaaccgca aaggaaaatc caagatcggg acgacaggca aaggaatcgg
     1561 tcctgcttat atggataaag cagctcgtac cggcattcgt atctctgatc tgttggatcg
     1621 ggatctcttt gcaaagaagc tacagaaaac catcgaagag aagaatcgga tactggagaa
     1681 gctgtatgat accaagggtt ttaccttcga ggagatctat gaaccttatg tagaggcagc
     1741 ggatcagctt cgaccctatg tgacggatac ctcagtagtg ctaaatgatg ctatcgatca
     1801 gggacagcgc gttctctttg aaggggccca gggtgtgatg ctggatattg atcaagggac
     1861 ctatcctttt gttacctcat ccaacccggt tgcgggtggg gtctgtatcg gctctggcgt
     1921 tggtcccacg aagatccacc aggtgattgg tgtagccaag gcatacacga cacgagtagg
     1981 ggatggcccc ttcccaacgg aattgaaaga tgaagtgggt aagaaaatcc gtgaagtggg
     2041 tcgagagtat gggacgacca cgggccgccc tcgccgtgtg ggctggtttg atagtgtcgt
     2101 cgttcgccat gctcgtcgag tgagcggaat cacgggtctt tcccttaatt ccatcgatgt
     2161 gttgacggga ctcgatacgg tgaagatctg tacggcttat cgatatcgcg gacgggtgtt
     2221 ggaaaactat cctgctaact tggatgtatt atctgagtgc gagccggtat ttgaagagct
     2281 accaggttgg caggaggata ttacaggggt acgtaaccta tccgatctgc caatggccgc
     2341 ccagcattac gtagagcgga tcacccactt gacagggatt cctctgacga tcttctctgt
     2401 aggccctgga agggaacaga cgattcaagt ccgccctgca tacgcttaat agataaaaag
     2461 cacgcacgcc ataaaaagct ggaatcgaaa ggacgttagt gtccgatcgt ttccagcttt
     2521 tttatgaagt agtatgaggg gctttctacc aaaataaatg gatagaaaac ccctaatgat
     2581 gacaagtata aaaagtcacg tttctaaagt atgtacatca cttgtgatac gtttctcccc
     2641 gattaatctt aaaggagcga tacacttgct ctaagagaag catacgcatc aactgatggg
     2701 gaaaggtcat tttggaaaaa gaaagtgaat aatcggctcg ctgtaataca gctttagaga
     2761 gcccatagga gccaccgatg ataaaggcga ctttacttcg tccataggtg gctaattggt
     2821 ttaagtgatt ggctagggtc tctgaagaga aagcgactcc ctggatggca agggccatcg
     2881 cataggtatc tgaagagagt gcacggagaa ttcgctcccc ttctttggtg acgagttgct
     2941 cgatctcagc aggggatagg ggttcctgtc ctttctcttc tgtgatctcc gtcacttcta
     3001 cttttgcgta gggggtgatg cgctgaatgt aatcctctac gcccatccgc aaatacttct
     3061 cctttatttt gccgacggtg atcaattgaa tcctcattcg atccctccaa cggtggtgtt
     3121 cgatacccca tccccttacg ggttactagg gtgagcagaa agacgatagg caggtgttcc
     3181 cccgcaccag tggcaggttg cagtctttgc ttcatctggc tcacatgggt taaggtcagg
     3241 agcaatttct acttcgtcaa caagctggtc gagaacaact tcgacatgct catcacaagc
     3301 ataccatttt atataaattt gatcggtacc tgccatgtaa cgtcctccaa taaagtcatt
     3361 cctttaagtt tagcatgaag tgagagggga tgcacctact gagctacaga gcaggtgaaa
     3421 gaggattacc ttatgttttg tacctgggtt gttaaaggtt gtggttagcc acaacctttt
     3481 tatttgacca aacagattta gtaaaaagag gtcaggtgta gtggccagtt ctttttatca
     3541 ttctctttaa tggcaagctc ttgtgcacaa tcctccatac atcctgaatg atggatatta
     3601 aacgtaccgt atgttcatta tgttttcttc tgataatctt gtgagtttgt gagctaaaga
     3661 ttctaagcga aaatgtcggc tatacattat catattcaca ctcgctgatt gcagttaaat
     3721 tttaggtaga tttaaggtgg atcttggatg gatttatgag gggtccgata tgatattccc
     3781 tgtaaaccac gatagggagt gaaatcggtg actgagatga ttatccagac agagcgctta
     3841 acaaaaaaat atggcggcca cgcctctgtg aacaatgtaa accttcaggt tgccaagggt
     3901 gaagtatatg gatttctagg gccaaacggt gctggtaaaa caacgacgat caagatgcta
     3961 ttgggattgg ccaaaccgac caagggatcg gtcacgatct ttggcagaga tatccaagag
     4021 gatcgaaaaa acattttacg acaggttggc tccctcgtgg aatctccaac ttattatggt
     4081 catctatctg gccgtgacaa cctgaaagtg atcgcccagg tactcggtct accgaaaaaa
     4141 aatattgaag aggctcttca aatggtccgt ttaactaagg atgcggatcg cttagtgaag
     4201 ggttattcac taggaatgaa acaacgactg ggtatcgctg ttgctttact tgcaaaacca
     4261 caattactca tcctggatga gccaaccaat ggtctggatc ctgcgggcat tcgcgaaata
     4321 cgagaattga ttagtcgatt gcccgaggaa caaggggtta ccatattaat ttctagccac
     4381 ttactctcgg agatcgaaca ggtagcaacc tcggtgggaa tcatctttcg tgggcaattg
     4441 attttccaag attcccttga ggtgttaaaa caacgagcca aagggagaat tgagttagaa
     4501 gtaagccggc ctactgaagc aaagaattac cttgaaagtt tgggatggca accctttatc
     4561 gacgaagagc gcgtctgttt tactccgatg gcccgggaga aagtagctga tgtagtagaa
     4621 aatttagtgc gaggggactt ttcggtatat gggatgaaca aaattagtca atcccttgaa
     4681 aatatcttta tcgaattaac tggaaaggag cagagtttat gatggggttg cttttgtccg
     4741 atgcacgaaa aataaaaggg acatggattc cctggttatt gctcgttgct cccatcggat
     4801 ttagtttgct acaagttgtg aactatatga cacgcccaga aatactaaaa ccccttggtt
     4861 gggtaggtct gatggctcag gccaattact tctggcctgt tgtgttgatc ctaggatttg
     4921 cgattgcgac atcgatggta gccgggatgg aacatgatgc aagttcatgg aaggtgatat
     4981 tttccctccc gattaacaag ttttctacct atgtaagtaa gttcttcttg ctactgatct
     5041 acattattgg atttgttttt ctcactttga ttgggttgct tcttgtggga ctcctctttt
     5101 ccttaggtcc tattaaatgg tcactggttc tcgagcaact tttctatcca tgcttagcag
     5161 gtattcctgt gctcgctctt caactatgga tttccatgat ttttcataac caagccctat
     5221 cgattaccgt cgggatcatt ggtgcgatgc tatgtttgtt tctcgcctat tcttcagtga
     5281 agctctttaa tattctcccc tgggcctata ttcccttggc ttccccttta aataaaggtg
     5341 aatatatgca atggccttta tttggagtaa ttattggtgt ttttctacta ataattggag
     5401 gaatccactt ttcaaaaaga gaattataat aaggaagaag tgagtgaaaa atggaaagct
     5461 tagtatctct tcgatacttg cgttcggaat tttataaaat tcgttggtcc atgattatcg
     5521 gtatcttgct ccttgggcca gcgatttcat tatggatagg ttttggcaat ccaacagaaa
     5581 tgagcgaggg tgctaatgat tggctatggt tttttagttt gacagtgcac aagtatacga
     5641 tgtttttcta cccactgatt gtaggggtgt ttgctgcctt tgtttgtcgt tatgagcatt
     5701 tggcaaatgg gtggaagcaa atcttttgtt tacccgtatc acgctttcag atttatagta
     5761 gcaaattcct cttagtttcc ttactcactt tactgacgca actatgccta ttgagtgggt
     5821 ttcttatcgt tgggacgatt tatggtttga atgacccgct gccctggagc attctaatta
     5881 caaaagtgat caaggggtgg cttgcttcat tgcctttgat ggcattaatg ctagggtgtt
     5941 cgttactatg gaaaaacttt gctactccat taacattaaa cgtggtgttt attcttcctt
     6001 ctatgatcat gacaggttca ggtcttttag ggtcctggta tccatggtca caacccttcc
     6061 tggccatgat gcctaagcat gagtgggtaa ccagtattaa tccatttatg ctttttatgg
     6121 ggattttaag tacgttcatc ctcttcgttg tttctacaag tacgatcttt atcaagcgcg
     6181 attattaaat attggattga gtagctcttc tagctataaa aatatagtgg ggggttatta
     6241 tgaaatccgt tctattaatt tcggacaatc caatcatggt gaagttagtt atcgaaaaca
     6301 ccatgaaaag tgatattaaa atcgacttac aatcgcctgg tacactaacc cctgactttt
     6361 tgcaagagaa taatccgtat tctgcggttt tgatagatac cagtagtagg gatactagtt
     6421 tccttttggc gcttattcct ctttcacaaa aatatggcgt tcctattatc ttattaaatg
     6481 gagggcaaga tcacaccgac gttgtaagcg aattgatcaa agacttgtat cgaggatccg
     6541 tgatatccac agccccaata gataatgagc aagagaagat accaatcaat cgcaatgtca
     6601 tatttgactt aaaaaaccat atcattatca atcgcgatgt agagatttca cttccgaata
     6661 tcgaatatcg attgctaaaa accttatgtg agcgatcacc ggactattta agtacagagg
     6721 agctcctgga tgtggtgtgg ggcgaggata agtttgttaa tgtggatacg gtctatgtgc
     6781 atattcgtcg cctacggaaa aagatcgaag caaatccggg aaatccaaaa aatttgatca
     6841 atcaaaaagg agtagggtac cgaatccaca gtctttttga tccaggagaa tatagtatgt
     6901 atgatctgga gaagtctgtc gcggtgaatg gtctcaatta ggggatgatc ttgttggatc
     6961 acacgaatct attgcttgtc gatgatgagc cggaaatatt gcagctcctg acgaaaacat
     7021 tgcattcaga gggttttcag cgaattttta cggctgggac agggcatgag gctattcaga
     7081 tatgtgcaaa gcatcaaccg gatgtgattc ttttagatgt gatgttacca gacatggaag
     7141 ggtatgaagt ttgtaaaaaa ctacgagaaa ttacccactc tccgattttc ttcctcactg
     7201 ctcgcacaac ggatttggat aagctgatgg gatataacat gggagcagat gattatatcg
     7261 aaaagccttt taatccgctc attattgtgg ctaaaatcaa agcacaatta aaacgagatc
     7321 aactttccca aacggcggag gatattttcc ctcaacccta tgattttggt gattttaagt
     7381 tggttgaaaa tacaggccaa ttgtttgtaa agggtgagga gatatcgtgt actgccaagg
     7441 aatttaagct gctggctttt ctatgtaaac atcctcacca aatctttagc atgggccagt
     7501 tatatcgaca ggtatggggg gaagaaagtt ttggctacga aaataccgtg atggttcaca
     7561 ttggtaagat cagaaaaaaa atcgagccgg atgttagaaa gcccaaatat atcgtcacca
     7621 tccgtggttt gggctataaa ttcatcggca atctggtagg gtcccaatga aactagaaaa
     7681 ccgtttaatg gtaaagtttt taactggtgt agttactctt tctttaatat taatcgggct
     7741 atttctcttc ttttattatg gtgcggggat gttaaaggga ggtaagcaac aaccttccaa
     7801 tgatccagaa gcagtgatgg ggagaatggc atcagaagca actgtaagca acgacggccg
     7861 tgtagaaata agctctaaaa tgaaagagca attatctcgc aatcaggaat ggacacaggt
     7921 attaaatggt cgtggtcaag aagtaatgcg ataccgtgca cctaaaaatg taccagtgaa
     7981 ctactcccca agtgatttgg tgcaattgaa aaaagagatg cgtcggaagg gctataatat
     8041 ccatgtatgg aataaaaacc acgaaaaaga agagtatacg tggatattgg gcagaaaaaa
     8101 taactatgtt cttctccgaa ccctaaagga tgcgacccaa tggaaggatg gaaaaattta
     8161 tgttcctact tctttattaa gacaagtcca taagcaacgt ggatgggttc aaattctaga
     8221 cgaaaaggga cgggagattt acgaatttga aagaccaaag gatacagtga agaattatac
     8281 accaggtaag tttgtttata tggatagctc ttccctaatc tatttgactg gcaaattaaa
     8341 tggtaagccc gtaacctggg tatataatca tgcttctgag gtgaatgatc aggaaaaaaa
     8401 gaccaacctg acgattgcgg ctttattttt tacttctatc attgcttcct tatgtgtgtt
     8461 tgtttttttt gcttatcgat ttggtagaaa gttaggtgag cctctcctat tgatcttgag
     8521 gtggatacaa gatttatcca ggggagatta tcgaggctgt attcgagcca agtacgtgag
     8581 ggatccgcaa acgggtcagt taaaaaaacg atttcgcatt tatcaggaag tgatggaagc
     8641 attggagaaa ttaagtgttc agttgaatga ggtagaagag aaacgaagta gactggatca
     8701 atccagggat gagtggttag caggtgtctc tcacgatctt aaaaccccct tatcgacgat
     8761 aaaagggtat gcagacctct atgctcaccg ggaatatcgt tggtcaacgg cggaaatgga
     8821 gcattattta gagctggtta tccaaaaaac agagtatatt cagcacctga ttgaggatat
     8881 gaatatcaca tttcagatga agaatgaagc tttatcgctc aatcgggaga gaggagacat
     8941 gaaagaaacc ctacgcatga ttgttgctga agttctaagt gaagcggatg tagaggaatc
     9001 tcatattcgg ctggaattac ctaaggatac ccatgtgatg gcatcggttg atcccaaatg
     9061 gtttaagcga gcagtgatta atatcctgac gaatgcattt gttcataatc caccagatac
     9121 agaagtgatt gtggagctaa aggttgaaac aaatgtagcc ccttcttcag ttgatccagg
     9181 gctaaggata tcgatcaggg atgatggggt gggcatggat gcaaagacgg tatctacact
     9241 ctttcagcgc tattatcgtg gtcgtagttc gataaattcc agctatggaa cgggtttggg
     9301 tatggcgatt gctaagaaac tgattgaact gcatgatggt gaaatctccg tgaggagcca
     9361 tttgaataag gggacagaga tgaccattga acttccctca cgagagatcc cggcttcctg
     9421 atggattact taaccttgtg ttgttgaaaa cagcagacct acctgataag ggataatctg
     9481 ttgttttttt attttataaa aaacgtactt attttatagg aataatcatg attaattttt
     9541 atggtttata agatcttata tgataatata tggaaaaaat atatataata tcattaaatc
     9601 ttacatataa ttcaggtaaa attaagggtc aattcaggta aaagggaata attacactat
     9661 aatagaaaat gcattaacgt taatgtgatt aaaaattatt taaaggagtg atttgtaaca
     9721 tggctaaccc atttgatctt gatcttcaaa gcgtagaagt gaaacagggt gatgtgcaag
     9781 ctggatctgg tttgatctgt actcctggtt gtgacgaagg aacatttgaa agctggtgct
     9841 gttaagctca taaagcagta agaggtatga agggggagca ttcccccttc atacctttat
     9901 attaatatta caacattcat cagtagtgtt gattacccag aaaccgagga gatatcttct
     9961 gggcaatcaa cactactgat catgaatgga ggtcctcggc atgtatgaac cgattaatgc
    10021 atggatgctt cgtactccaa cgtggccaat cgaaaaattt aacgcattaa ctaccgataa
    10081 aaccatgccg ttccaacaac ttttgttaaa aacaatggat aagacattta tagagagtat
    10141 tgcgattgct agtccatcac tatatgaaga tctttcgcaa ttagaaggag atagtcatca
    10201 acgaaaaaca aaacaagtgg tcgccagtgt tttgaaatat gctacaagaa tgagtactcg
    10261 gccaacacct tttggtttat ttgcaggggt aacggttggt gagcttagcg aaggaacaac
    10321 gatttcattg cagtcctcag agaatcatat caaaagggca cgaccggata tggaatggtt
    10381 attaacactg atcgaaaaat tagaggaaga tatcgaaggg attcaacaga taaaggttta
    10441 taaaaatcaa ttggtcacaa agtcaggtgg acggttgtat ctaccctatc aaacaggtta
    10501 tggaagacag acaaatatta catcaaaaaa agaacgagtt tctattcaat taaatgaagc
    10561 agcgttgcaa gttttaaaag caagtagaga gccgattgtt ctgtctgaat taatcgcgcg
    10621 gatttcttcc tactactcca attttgatcc ggttcaaatt agaacgtaca tcctccaact
    10681 attaaagcag gaatttctca tcagtgaatt gcgccctccg ctcacaatca gcaatccttt
    10741 tcactacatc atcaatcaga tcaaagatat tccccggtat cacgatgtgt accttcaatt
    10801 agtagaaatc gatcagctac ttgaagattt caatgcttct ccaatgggtg aagggattga
    10861 gatttacctt gatgtgattc agaaaatgaa gagcatcaat gaaacaaaag cgtatctcca
    10921 agtggatcta ggattgaaaa atagagaatt gacattgaat caagctgttg ctgatgaagc
    10981 tgccaaggcg gcaacgattc tttggcgaat ttctcagaca gagaaaggtt taccccattt
    11041 aaagaagtat cgggatcgtt ttttagatcg ttatggacgt gatcgtgaag ttcccatctt
    11101 ggagcttttg agcgaagaaa gtgggttggg aagtcctgag gagtattatc ctgatgcacc
    11161 ttcaaccata agtgaaccac gtaatagtga aagagaacaa cgtttgctag agatgatgca
    11221 gacggcactt cttaaccgac agtatgtcgt ccaattagat gcaaaggcat tgaaggacat
    11281 aatccctccc tcggttgatg accgtgatgc tccatccacg gtggagctat atacagaagt
    11341 tctagccaaa agtgcaaagg cagtagatga tggtgagttt acgcttgtga tcgctccaaa
    11401 tccaggatct ggctctgctg gacagacctt tggtaggttt tttgacgttc tggatccctt
    11461 tacaaaaaat aaattacagg cggctcataa ggagataaac gatgctcaac ccgatgtgat
    11521 tacagcagac tgtgtctact ttcccactcg gggtagggcg gccaatgtct ccctagcacc
    11581 tggtttacaa gaatacgagc tagtgcttgg caccaattac gctagtgata aaaagaaact
    11641 atttttagag gatattgtcg taggagcaac attggaacgc ctttatttta agtctgtttc
    11701 attgggcaag gaagttactt ttacggccaa taatatgttg aattttcaat cgtcccctgg
    11761 tgtctaccgt tttttgcggg aagtttcctt agagaatgtt cgaatttggc actcctatga
    11821 atggggaaca ttaagagatt ctccattttt acctcgagta caggtagata aaacgatttt
    11881 gtctccagca aaatggaagt tatcgatggg acaacttgaa cttaagaagg aggcatcggt
    11941 agaggagtgg aataccgcct ttgatcactg gctgaaaaag tggatggtcc cacggtttgt
    12001 ctatatgggg gctacggacc aacgtctcct tttggatcta gaacacccag cccatcggaa
    12061 agagatcata aaagcagtgg agaataaagg aagggttcat ttatcagaat ccttttatca
    12121 gcagaataac gattggattg ttgatgcgga tcatcaccat tatattggtg aatttgtttt
    12181 cccgctcaaa aagagagaag ctctacctca cccatcccct gttactcctg tgatgaagaa
    12241 gctggctagc aatagtcgca tcaaacttcc agggagtgat tgtttatata tcaaagtcta
    12301 tatggcaaag agtaggcaaa acgattttat ctctaggcca ctttctcatt ttgtgaagaa
    12361 tgcacgtgag gagggcttag ttcagcgatg gtttttcatg cggtatggag atccagataa
    12421 tcatttacgg atacggtttt ttggggaacc agagaggctt atagccagtt tgattccgac
    12481 cattcataca tgggcggaaa gacttgtaga agaggggctt atccaaaagt tgaccatcga
    12541 tgcttatgat cccgaatttg aacgatatgg cggcccgcaa ctgatccacc atgctgagcg
    12601 tgtttttgaa gcggatagtg acttggtagc ctatctagtc aatcaaattc gctttggaaa
    12661 aattgagttt ccagaggagt ttgttgcaag catgaatatg ctggacttca tggagcagta
    12721 tggtcttaat tttgaagacc ggctcttgtg gctcgatcaa atggttcagc ctgatgaaca
    12781 ccgaaaagaa tttcagttat ggcgaagagc gattgttgag tgtacattgc ataatcctgt
    12841 gtgggctcaa ttacttgggg tggaccaaga gataataaag ggtttggcag ataagcggaa
    12901 tcaaggcatc actgaattta agagtcaaat ggagagaata caggagcaga atctcctttg
    12961 gaatcatccc cataaaatct taggaagtat gcttcacatg acctgtaatc gattaatggg
    13021 ggataacagc aaagaaatga aggcgagggc gtttgcaagg catgctctat acagtcagca
    13081 atacttacgg aagcagttgg ttagtacgta gttggaagga ggaggaacat gaatagggat
    13141 aaccaactag agaatgtatc catttataac ttcgtgaaat tagcatccta tatcaagcgg
    13201 atttttacca ttctatggag tgttcatcct ctgcaatttg tttcaattat tgtgctgacg
    13261 attttgcagg gggtagctcc tacatttttt atccttgcct cccagtttgc gatcaatcaa
    13321 ttggttagta gttggggaag cggatttcac atcgtgatta atgccatgct cgtattaggt
    13381 ggggtcatgg tatttaatga gctttgcaac attttacgtg tttatgtgga tcgtatcttt
    13441 gaggtttccc tatcgtacca agtggattta cttgtcatgc aaaaagcgtc cacgctacat
    13501 ttgagtgact ttgaagatca tgaggtacag gatcaaatca aacgagtaca aaatgaatcc
    13561 aatatccgtg tctatcaagt atttaaacag gtgatgaccg tgctctcagg aggggtgaca
    13621 ctggtctcct ccgcacttgt gttgttcgct tggcattggt gggcagcggt attgatcttg
    13681 ggtgtgccta tcattttctt tcccctcctt ttgaagttag gagaaaaaga gtttaaatat
    13741 ttatggaaaa gagcaccaaa gacaagagag ctttggtata tcaactacat tatgacccgg
    13801 gatctctcat ttaaagaggt aaagctgtat caactgggtc cttatctaat cgatcaatat
    13861 caaaaaattc atcgcagttt tattgcagag gataaggaaa ttgctttaca aagaagaaat
    13921 ctctcttttt tgtactacgg aatcaactac acggctgtga tgattgtcat tcattttatc
    13981 ttcaaagcgg cttacatgaa gcaattgatg attggtaacg tagtggggta tttacaagca
    14041 atcaatctga cgttatctac ggcgcgtaat ttaacgcaag aagtgatgct cttgtttcaa
    14101 aacaatctct ttttggagca attgttcact tatttagata tgaaggtaga atctcccgct
    14161 gagttaatcg agggaaaaaa gcatttacaa tcacccatca cccaattgga gttacgaaac
    14221 ttatcttttc aatatccgaa cacggacaag cctgtactaa agggtattaa tttgcaatta
    14281 catgcagggg aaacgttagc gattgtaggg ccaaatggat ctggtaaatc gacgctgatt
    14341 aagattctca cccaaatgta taaccagttt actggagagt atttgatcaa tagaacgtca
    14401 atccgtaaat acgattcaga tgaggtaaac agaagaatcg gaggcgtttt tcaagatttt
    14461 gtacagtatg agatgccttt gcggcacaat attggttttg gggatgtaga aaaaatcgat
    14521 gacgatttag cgttgatgaa ggcagctgaa aagggggggc tatcctctct agtccattca
    14581 ctgcctaaaa aactcgatac acaactcggc aagctattta aagatgggca tcagttatct
    14641 ggagggcagt ggcaacgggt ggcgattgcc agagcctact taagggacgc agatatttgt
    14701 ttgtttgatg aaccaagctc atttttggat ccccaggcgg aacatgaggt atttgagaag
    14761 tttaaggatc ttgtacgtga tcgaatcggt atttttatta ctcatcgttt atcttctgta
    14821 cgctatgcgg atcggattat cgtgatggat caaggacaga tcgtggaaat gggttcccat
    14881 gatcaactga taaatttaaa cgggctatat aaagatatgt ttacaaaaca agcagaaagt
    14941 tatctggatg cgaaaatatc aagcgcttaa ggggaggggt tggatggaga ataaagtgat
    15001 tcacagacgc agggtgaggt cagctattgc cgataaagga ttagagatta gccagaggat
    15061 agcagagcgg ttggtggatc caattcaaat caaagaaatt gtggagcgcc ccgataatgt
    15121 atctgtgatg ggagcaactc cctgggggga taccagtctt tcccatgggt atcccgctac
    15181 cgtcctcttt ttttcccagt gggatcggta tgagccggat cagaaatggg attataaggg
    15241 acatgctcat attgtagaaa tgcaacgggc gctagagtcg aatggaatcg gcagtatatc
    15301 cttgtttggc ggcttgacgg gtgtggcctt tgcttgtcaa gcggcgtcaa gggaggggga
    15361 gcggtacggc aattttttaa aggtgatcca tagcaaaatt gcacaggaga cgaagcgatt
    15421 tatcgagggg gacaacactc ggcgcaaatc agaggtcggt cttagtccaa aggtgtatga
    15481 tgtgatctct gggttaagcg ggatcggacg ctatgcattg aatcaccctc atcatgatga
    15541 attaaacgat gtacttgagc aaaccctgca ccacctcgta gaggtgagtc atgatattga
    15601 agtagatcat catacggtac ctggttggta cattcctcaa cagtatcaat ttatggagag
    15661 agagaaggag ctttttccaa aagggaattt taattgtgga cttgcccatg gtattcctgg
    15721 gccgttggta ttgctctcct tagcatcgct ccgaggttat cgagtggacg gtcagctgga
    15781 agcgattcaa cggatgagtg attggttagt taagcgagcc tatcaggatc gatatggtgt
    15841 tttgtggtcg gatcgcattc gctttgaaga ggaggtttca aggaagcctt cgcaaaaata
    15901 tttttcgcgg gaagcttggt gttatggtgc gccaggagtt gctcgttcat tatatttagc
    15961 tgggatggca ttaggagatg aagagttaaa gaaactggca attcaagcag taaaatcgag
    16021 cttcatgcgg ccggaggaac taagcaagct tgaatctgca accttttgtc atgggaaaag
    16081 tgggatcctc caaatattac tgaggatggc gaaggataca ggtgaggaaa tttttgtgaa
    16141 acatgcggaa ttgatggcaa aggagatcat cgatatgttt caaggggagt caccctttgg
    16201 ctatcaggat cttgaggggg gaagggggct caataaagca gggctgttgg aaggtgtttc
    16261 tgggatcggg ttatcgttaa tgagtctaag tgaaaaacag gatgctgatt gggatgcagc
    16321 cttcctgatt tcataatgga gtgagagcat atggataccg atcaattgaa aataaagaat
    16381 ttgttggtgg ggataggtgg atcgatatcc gtgctagccg ttccatctta tttgaccctc
    16441 tttgctcatt tttttaaaga agtaaaggtg atcatgaccc catcggctgc tcgcctactt
    16501 ccacgagaaa cagttaatct gctatgtgca ggcgcatata ccgatgagca ggaattttcc
    16561 caggagatca gccatgtaga gttaactaga tgggcggatg gattggtcat tttacctgca
    16621 acagcaaaca ccatgggcca ggccgcaaat gggttgggtg ataacttact aactacggcg
    16681 attcttgcct atccggaacc gattatttat tttcctaata tgaacgaaag aatgtggaga
    16741 aaaaaatctc tccagcgaaa tatcaaaaca ttagaggcag atggggatat tgtagtagag
    16801 ccctctcatc agatggccta tgaggtggcc tctggcaaaa tgcgacccaa ttacacgatt
    16861 ccgtcaaagg aaaatgtaat gaaagtgatt tataaacagc tggtcggtaa tgtacaaacg
    16921 gttagtaaat cataacctta atgataagaa gagggggaga ttctaaagat ggcgatgtca
    16981 gttaaacaag cgatggaaac ccgttgtagt attcgcacgt atctacaaga gcctgtacca
    17041 agagaggata ttgaggagat cattcgttta acgcgcttag cacccagtgc gtggaatatt
    17101 cagccttgga gatttatcgt ggttaccaat aaagaaacca aacaggagct ttataacatc
    17161 gcgaataagc atccgcaagt agagagtgca ccggttgcca ttgttgtgac gagtgatatg
    17221 gaggatgcca tcgccaatct ggaagagttt atccatccca gcatgcctga ggatgcaagg
    17281 gcgtggttaa cgaatacgat accaaaaata tttggtgagc aaaccataga acaacgtgga
    17341 caatggggag tagctcaatc caatatcgcc ctgggctatt tgctgatagc gattcgtagt
    17401 cttggttatg attcatcgcc gatgtatgga tttaacccct ataaagtacg cgagttgttt
    17461 gagttatccg atcatgtaca aattccttcc attgttacct tagggaggcg aggagaggaa
    17521 ggaagagaac accatcgaca ttcattagat aaattgattc gttatgtttg acactcccac
    17581 agctgaagca gtgggattct tgggagctcc catctaccga caggatcgat tccaagctta
    17641 gacggtctgc ccaaccgcaa gtacacgaag tccttcagga ttcgttccat ctggctagaa
    17701 agtgattaaa tgtgaaacga ctacatccca tagatttatg gatgagaatg gtttgttcct
    17761 ttgttggata caagcgaaat ttaaacgctt tgtgcatggg tttacctccc ctttatctaa
    17821 ttatatacgg ggattgtcag ccttgcgaga gggaagatct cccctctctc gtctgacgct
    17881 cgctttcatc ccaaccctga agggctgggt tttcccgctc gtaatctata ataagatcag
    17941 cctaaaagtt tcagataata aataagacaa gagaagaatc ccggtggagg gttacttctc
    18001 ttgtttttta ctattttttt aaaaaaatta tggcgataaa tagtcacaca cctatttacg
    18061 catcatctat tttttaaatt aggttaatcg acagccctgc aatggatcct ttcaacctcg
    18121 taattaatcc cctcttcttg ggggttgtaa gcctgaatgg gtaatcgttt tgcagcggaa
    18181 ttacaatgaa actgttacgc aaaattttcc cagtaaataa ttgacaaaac aaaacctact
    18241 gtttataatt ttcacgaaaa atagaaaagg gaggcacgta cgtgatcaat cgcaaaagag
    18301 gtttacgaat cccgttactt ggtctggttg tcgccgtctc actctcttta ccactgatag
    18361 ggctctccag cgcagaagct gctccatcca agtccaaact gtcgccagac acgatgatct
    18421 ctaatgatgg tacgattact gcaccaacag caccttttag taacgaattc agcaagcaac
    18481 gggatggagg agctactacc tccagttaca aaggaaacgg tgaggctctt gccaagcaaa
    18541 catccattgt aaccaaaaaa gatacggtaa aaaatgatcc tccctttatc ggggttaagt
    18601 ccatcatcgg ctccgatggc cgcatacgag tcaaccctac aacctccttt ccctacagtg
    18661 ctattgcaca aatctctagt gatattggcg attgcacagg ttggtttatc agtgcagata
    18721 ccattatcac cgctggtcac tgtgtctaca acacaggaaa caacaagtgg gcatcctggg
    18781 cgaccatcac cccgggtaga gacggaaaca atgctcccta tggtacctat agtgcaaaat
    18841 ccttccactc ggtactgggt tgggtaacca atgaagatac caactatgac tacgctgcta
    18901 tcaagatcaa ttccgacatc ggatacacaa ccggttggtt cggtcttcgc ttgcaacccg
    18961 gctccctaac cggtacagcg gaaacaatca gtggatatcc tagggacaaa gcctatggaa
    19021 cccaatggcg ccacagtgat caaattcgtc aaacctatga tcgaaaatta tactacggca
    19081 atgacacgta cggccaaagt ggctcccctg tctatacaaa tgactactac agtgttgcca
    19141 tccacaccaa tggtggaaat ccctataata acggaacacg cattaacgaa aatgttttca
    19201 acaacctcct atattggaga gaccactaaa aacaaaccca ctcgatagga gagtcccctc
    19261 tctagtggat tgcagacagc acaaaatcgc ccgctattag cctatagcgg gcgattttgt
    19321 gacttgatag ctcctaggat ttttctctta atttcacttt ggctgtcatc tttttcccgt
    19381 cacggtagaa ggtgaaggtg gttgtttcgc cgacttcttt ctctttccag agataggagc
    19441 gaagtgccga gccatttttg atcggtttac cgtccagggc tgtaataacg tctaatcgtt
    19501 gtagattggc ctcatcggca ctgctaccat tggttacatt gatgatggct acgccattac
    19561 ggaccgagtc aggaaggttt aaccgctgac ggtcgtcgtt ggtgatcgtg tctagatcac
    19621 gcaattgaat accgaggaag ggtcgcttta ctttaccata ttggacgaga tcattgattg
    19681 ttggttttgc gtcattggaa gggatggcaa agccaagacc ctcgacaccc tgctccgcaa
    19741 ttttaaggct attaattccg atgacctgtc cagcgacgtt aacgagtgct ccacctgagt
    19801 tcccaggatt gatcgcagca tctgtctgaa tggcatccat cgccatgttc tctgaaacag
    19861 cgatttgtcg atggggggag ctgatcaccc ctgatgttac ggactgagaa aactccaatc
    19921 caaggggatt tccgatggcg atggcaggtt cgccagcctt caacttatca gagttgccaa
    19981 attgggcgac cgcctttaca tactcagagg acatttccaa tacggctaaa tcagtgggct
    20041 catcttttcc aatcacgcgg gcgctcactt ctttcccttg gccttcacca gggatgacca
    20101 cacttacctt gtcagcacca gcgactacat gttggttggt tacaactagg gctttacccc
    20161 cctgtttttt aaagatgact ccagaaccag tcccctgttc gacagttttt tgtgtaaagg
    20221 gatcacttga tttctggttg acgattccaa ctacagcggg gcgaaccttt tcgactgctt
    20281 tggtgatatt ggaagtaaca ttgacagaac tcgcgggacc tgtgttttct gaaacggcag
    20341 gtccttggaa ggattgttga ggaagaattc cggatcgaac taaggcaggt gacacgatta
    20401 gtaccaggag cccaccaacg attgctgaaa tcaaagcaac ccaaattagg ctcttggtac
    20461 ttctattccg atcattataa aaccccacgg gcacattcct ccttgaacca atcaaatcag
    20521 acgtaaattc tctaacatta tgtgatgggt gtaactttat tatactgttt ccctgtggtg
    20581 ttctaaagga gagatagcta gaaaatgttt ttaattttca aacgtcaagg tttgcgtcct
    20641 ttctctgtcg gtcaaactga aagaaaaagg taaggagcac ggcggatgag ttcaaataaa
    20701 agaacggagc cgattgatcc atggaccttg gtcaactggg gtgcgcagtt ggctgatctc
    20761 aaggaagcag atcatcgtac tcgtctctgg ctgggaaccc ttattcaggt aatgatcgat
    20821 aataaactcg tatccatcga ggagttagaa aaaagaatgg cagagctaga tggctagttt
    20881 ttgtgcaaaa aaaaccctgc aacctatgca gggcagcgga ttcaacagag atgtaggggt
    20941 aacccaaaag aatggctagg ttaacatcaa tatggctcgc tgttaaagga ggacacttat
    21001 tattatagcg gctttccctt agggaatcat gagaatgaga ttaaaattag ctgtgattga
    21061 tctaagagaa tgacagctat tttttttatg atcgttttcg tatttttctg agaggagtgg
    21121 gacgatccgg ccaggtttct cgtaaatgga tgtcctttcc tacctttaac ccttcttctt
    21181 cgagaatgct tcgtacggtg agatgggcta gttcggtcag gttgttatcc tgactcaagt
    21241 gagcgaggtg aacatcttct ccttcgccct gaagaatgtc gaggagggct tctgcggcat
    21301 cttcattgga tagatgacca acgtcactta aaattcgtcg tttgatgttc caggggtatg
    21361 cacccatgcg aagcatctcg acgtcatggt tggactcaag aatgagtgct tctgctcctc
    21421 gtatcttttc aacaatacgc tgattaatat aacctgtgtc agtgacaagg ccaagggaga
    21481 catcttctgc gtgaaagcaa aatcccatag gctgagcggc atcatgggaa atggggaagg
    21541 attcgatggc aagatccttt aattgtaggg tagatagcac aggaaagatg cgttgctgat
    21601 cgggatgaat cgccccaacg ccactgggta agcttcccca agtagcttca ttcatataga
    21661 taggaagttg gtaccgacga gcaaagacac ccagcccttt aacatggtcg atgtgttcat
    21721 gggtaaccaa aagggcgtcc aactgggtag gatcggcacc gattgccttc atttttgttt
    21781 ccaattgttt gccagatagg ccagcgtcga tgagaatgcg gatgttctcg gtttctatgt
    21841 agagggagtt tccggtactc ccactggcca atatgctgta cttcatggga taggctcctc
    21901 cagcttctat tcgtgattgg tttcattgac ggaggattca attgcgccat taaaagcatt
    21961 gacaaagaag gtatgttttt tggtttggat ccgccacatg ggttgtaaaa tacgaacctt
    22021 tttatcataa gactggctat gatatcccaa ttggatattg gtgacggtct cttttttttg
    22081 gatttgtccc ttttcaatta agttgatgag tgtcgtagtg gcagcgactc cgggccgttt
    22141 tgccccattt tgggattcaa ccttgaaaag agattgtcgc agggaggtca ggtggttttt
    22201 attcttccat ttcgcctcga tcttgccgtc gaaaatgagg tttttgccat atcgttgata
    22261 ataaacttga cgtttatcgt tggattcatc gggttgaaag acgtagttat ccaggctatc
    22321 gatatagcga ttaagggttt tctctcgatc tccactaaca gttagaggag gatcaaaggt
    22381 ttgcacccag gtaccatcgg tgtcattggt ccaaggttcc ttaaaggaaa caggacttcc
    22441 tttaagggag tttacttgag gaggttccgc aggtgtttta ccaaggatcg tgatgtccgc
    22501 ctctgtagcg atttcattaa gctcttcctg tgtattggta gcctgatcat cctgggattg
    22561 ttctgttcta gcattgaata gttggctagc tagaaagatg tttaaggcga ggaaggccat
    22621 gatgagtata cttttggctt tgctccattc catgacgggt cacctcccag gtgatcgctt
    22681 ttctacataa tttcttgtcc catcctccaa ttgaatgatc catgtgggaa tgaaagtaac
    22741 ggcctgatct ttgatatccg ttcggtatcc agggtagata ctggttactt tcttctctaa
    22801 cgagatcccc ttgcgatcca attcagcgag tagttctttt ttgtcgggta ggtaactcac
    22861 cttcgttgcc tttttatctg gttgtaaggc tgggtagaag agtgagcgat catagcttgt
    22921 tactcctttg cccaccgcag agagacgtaa agtggctggg gtaattttct ctcctccatc
    22981 ccaaaagaca gggaggccgt tggtgtaaag gcggaatcga aagaaaggag tgacttggtc
    23041 tgggtcattt tctatatcgt caaggaggaa attccccgtc catccttcgt gtcgacgcat
    23101 aaactgctgg atcaagtcca gttgatctgt caggctgaat tccgattcgg tggtggaatc
    23161 cgggcgattg taagtgatta aattcttggc tgtattgtgt tggagggttc gagtggtatc
    23221 ggtgtacatc gtagcacgat ctagggtgag ttttttttcg attagattag gatctggaaa
    23281 tagtgcaagc tttagatcat taatcgtaat cttttttaaa ggatagcgca gttgctgaac
    23341 ggcgagtgga tcatttggta gatagagggg tcttggtatc gcgcccgaat ttttcttagg
    23401 aagggtagcg gataagaaag gagcatttag tttgtccgcg acctttatta aatcagcaaa
    23461 ggattccaga gtcgctttgt attgcacggt ttttcctgtt tcatctgaga taaaacgagc
    23521 agattgatcg cccgcagcat tttgatagat ccatacccgg ctgaccgagc gtagatccgg
    23581 ttttggtaga tccgtggtga agaatgcttg catgatctct ggagagaggt tgttgttaaa
    23641 gcgcaactca atcccatctt ttttcgccat gaggttattc cagtccttgt tggatggtgt
    23701 caccttttgt ggtctcgtca gctcagttag atgtacattg gaaaggagat tacgaatttg
    23761 actcttttcc aagtttcctg ggatttgttg atgctttcca ttctgatgga tgagaatttg
    23821 actgggtgca gcaatttcgt ggactccttg tttttcaaag gattccttga cgatcttatg
    23881 gggataggaa taatcatccg gcgtcaatac ctgctcatag gaaggagagg tataaagaag
    23941 aatccccgac tgcacaaagc tagtcaggat gagtatggtc aagaggacgg atttgatgtg
    24001 atctatcatc ggattacctc cggtacatag gggggcagcg taaagtggac ggtggtgccc
    24061 catccatagc ggctatctat atcgatcgat ccaccgtggg cttcgatgat ctctcttgca
    24121 atagccagtc caagtccagt accacccata ttacgagagc gggctttatc cacacgataa
    24181 aatcgctcaa aaatgagggc gagatccttt tgaggaatac cgatccctcg gtcagagacg
    24241 gctactacaa cgaagccatc cgaacgacgg cgagcagaaa cggtgatact tctttcttca
    24301 ggagtgtatt tgaccgcgtt ggagatcaga ttgtccaata cttgatccaa ctgatcccga
    24361 tccccgtata ttttgggtaa atgatcattg aaacggaagg aaatatcaat atttttttgt
    24421 tccgcagaaa tggaaaatcg ctctacagca tccgagagaa tctcctcgat tgctacgggt
    24481 tgccgattaa agcgaacctt ttgggcgtcg agacgggata gttgtaacag gtcgtggatg
    24541 aggcgggtca ttcgctcgga ttcctgacgg gtgacccgta gaaaacgttt ggctaactcg
    24601 ggatcttcca tcgccccacc ttcgtcgagg gcttctaagt agctcttgat ggtggtgaga
    24661 ggagtccgta gctcgtgaga gacattggcc acaaattcct tccgttgtcg atctagttta
    24721 ttctcttcgg taacatcctg gagaaccgta atcaagccaa cggtctcctc tgagcggcgg
    24781 atgggggtaa aggtgatctt gactaccgtg ggctcatctt catcctcacg atttaattcc
    24841 agataggctt gccgttcctc cactagagga aaagggagag gctctgataa gggaagagcc
    24901 tgggtgatgg gatccccttt agcaatcgtc ctccctagga tgttgcctgc ccgttgattg
    24961 atgacaatca cacaccctcg atcatctgta gcaataacac catcgttcat attagtcaaa
    25021 acggactcta attttccttt ttcctcttcg ttttgggaaa gagcttcgcg aaggtgttgc
    25081 gcgaggtggt tgaaggcggc agcgagttga ccaatttcat cattactttt cacagctact
    25141 tttcggtgaa aatcaccaag agccatttca gaagcttgtt cggtgatctc tttaaccggg
    25201 ttggtaatgg tacgagccag gataatcccc aagatcgccg tgccaactaa ggagaaaagt
    25261 gaaatttgta gaagtttgtt gttaattgtc cgaatggtgt cataggtttt cttcatcggg
    25321 gcttcgatgt agatggcacc gatgacttga tcattctctg taattgcttt ggaataaagg
    25381 atgagaggtt gattgtttgg gcctcgacga aactgtgtat cgttggtgtt aactccacgg
    25441 agaacagaag ttacccgtgg atttttttgt ccaatcttgg atttgttttc tgctgtggta
    25501 ctaaggacga ctccatcttg atcgaggagc tgaacgattt gccctgagcc tttatcaagg
    25561 atatagatgt tttgtaataa tttgtttaat cgtttgcgtt tttcagcgga attgagctgg
    25621 ggcttagcca gctccttagc cataccgccc ggagagatta gtagatcggc ttgtcgtttg
    25681 agacgaactt ctagatcgcc aacgtaaaaa tcctctaact cttgaaagaa atagacacca
    25741 atcaattgga tcgcgatcaa taggagagag atgtagatca gaaccatctt ccattgaaca
    25801 ctattaaata aacggagcca tttgaaaaat ttcatcggtc tccttgggga tcccgcatgg
    25861 tgtagccgat accgcgccgt gtgatgatat agatgggctg gctgggatca tcctcgattt
    25921 tttcacgtag acggcgaatc gtaacgtcta ctgtccgcac atcaccaaaa taatcataac
    25981 cccagacgga ttggaggaga tgttcgcggg taagcacttg gttgacgttt ttggccatat
    26041 ataagagaag ttcaaattcc cggtgagtca attcaatcgg ttctttttct ttggagacaa
    26101 gataacttcc ctgatcgatg gcaagggagc cgactcgaag gatctgggat gtggtagatg
    26161 ttgtaggctc ttcagcacgg tctcgggtac gacgaaggtt tgcttttacc cgggcgagga
    26221 gctcacggtt gctaaagggt ttggtgacat aatcatccgc gccaatttca aggccgagta
    26281 ctttgtccac ttcagaatcc ttcgcggtga ccataatgat agggacttga tgatgt
//
