LOCUS       NZ_FNNQ01000006        26462 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Marininema mesophilum strain DSM 45610, whole genome shotgun
            sequence.
ACCESSION   NZ_FNNQ01000006
VERSION     NZ_FNNQ01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Marininema mesophilum
  ORGANISM  Marininema mesophilum
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Marininema.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900106775.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:02:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,196
            CDSs (total)                      :: 3,130
            Genes (coding)                    :: 3,066
            CDSs (with protein)               :: 3,066
            Genes (RNA)                       :: 66
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (5S, 16S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 21 of 64
            Pseudo Genes (incomplete)         :: 50 of 64
            Pseudo Genes (internal stop)      :: 5 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 147649
            Orig. end                         :: 174111
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNNQ01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26462
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26462
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26462
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16462](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16462
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    483..496
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.44"
                     /tool="antismash"
     gene            691..1242
                     /locus_tag="BLV90_RS07640"
                     /old_locus_tag="SAMN05444487_106147"
     CDS             691..1242
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016324912.1"
                     /locus_tag="BLV90_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106147"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_091738745.1"
                     /transl_table=11
                     /translation="MAMNNGVLTRNQLLTAASNIVSEKGVSKLTLEAVANQAGVSKGGL
                     FYHFPSKEDLVQAMIDELSVDFKNDMKDNLQAFHGKGQWTRAYVETMFMRVDDGLKMSS
                     ALFASMFTNPKLMEKAQLQYKGLQEQIQNDQIDPVHSTIARLAADGLRFAEMFGLAPLD
                     KETRDKVHGELTKIITKGGI"
     misc_feature    1323..1338
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.08"
                     /tool="antismash"
     gene            1505..2623
                     /locus_tag="BLV90_RS07645"
                     /old_locus_tag="SAMN05444487_106148"
     CDS             1505..2623
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV90_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444487_106148"
                     /product="hypothetical protein"
                     /protein_id="WP_091738748.1"
                     /transl_table=11
                     /translation="MRKKIGEKSVKMMKMMTVFALALAFVFSGGFIGPVKASAAPDNEK
                     KLPEKYIQGYKIDKDGKKTPVYNTDNAPKGKVAPKADEPTSPYAANYPKLSEDPYAPAL
                     ESGTTKTDPPGKIGDIVYFKLNGVQAHFNGSEEFTDAGVYLEKKSDGTIEKGLYEVKTG
                     ATNTAPLEKLNEERAQNGEAWMVEKYGPSMAWSKAFDGTSKLKRESKFKLLGTSTVANS
                     AEWWSGLDIEHGVSETESYSLAWTIGFKLSIEAGGGFVPGKTTTEFSTQLTNTFGQETT
                     ISDKVTYKDQTKVPKADNPAYQYDVYRGALYQLTNTYTLEPGTGLQELINAEEFPGDFG
                     FKQGLANPSFQYNSKELYYPVTPGSHLGPGGQ"
     misc_feature    complement(1521..1536)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.87"
                     /tool="antismash"
     gene            complement(2851..4146)
                     /locus_tag="BLV90_RS07650"
                     /old_locus_tag="SAMN05444487_106149"
     CDS             complement(2851..4146)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018704865.1"
                     /locus_tag="BLV90_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106149"
                     /product="MFS transporter"
                     /protein_id="WP_091738751.1"
                     /transl_table=11
                     /translation="MYFSSSSQKFRWMVLGLATGTQATATFVTYGVGPLAAIWQQTFSL
                     SQAQVGLLISMVNIGPLMSMLFIGRALDQHGERWIVGVGSILLGLTMGVSSLLSSYLSL
                     LVTLLLVGIFYGTAQPGGNKVVIKWFDSSQRGLATGIRQAGIPIGGALAGWLIPLLSVR
                     YDWPIAVQLQASSAFIGGLMFLLIYRDPVKESKIPTQHVNFIGELRNLSRKKSLYPLLF
                     SGFSLISFQMVLVAHLMLYLKSKIEHMTLVSTGFMLSLCLLFGMLGRITLAWLSDTIWK
                     GNRIKPLEMILWMSVVGLVVLVVLPEKIPIWCIYVVCSWLGFFGVGWYSLYIVEIGEKA
                     KEHSVGLTVSYALTINQVAIIMAPFFFGLFVDWSNSYALPWIGLASLLSASGIWLRKSS
                     SIPFIEKRMEFNTPISGQNTPHEKRKKNRKIV"
     gene            4288..5139
                     /locus_tag="BLV90_RS07655"
                     /old_locus_tag="SAMN05444487_106150"
     CDS             4288..5139
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="BLV90_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106150"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_143035016.1"
                     /transl_table=11
                     /translation="MDIRDLQIFQTVSRHKSVTKAANELNYVQSNVTNRINRLEQELNA
                     QLFHRSGKGMSLTSAGRNLIQYADPILEMVNEAKNAFLIPQGPLKLGSTESTAAVHLPS
                     LLMKYHEAYPQVDVSLTTASSEELIKRVLHYELDGVFVVGPINHPELKAFTFMEEELVL
                     ISSPHHPPIHSARDLQHETLLVFDVGCSYRSRLEQWLSDEKAHSVKRMELSTLEGLFRC
                     VESGFGVALVTRSVAQEYKRGEIKLHPLSTDYHQSTTVFIQRKDRYQSPALSRLVELME
                     NE"
     gene            complement(5230..6000)
                     /locus_tag="BLV90_RS07660"
                     /old_locus_tag="SAMN05444487_106151"
     CDS             complement(5230..6000)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="BLV90_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106151"
                     /product="ABC transporter permease"
                     /protein_id="WP_091738757.1"
                     /transl_table=11
                     /translation="MSELFMSEWERIWARRKTMVSLGIFILLLGMSTFLLHRGGIGFYT
                     AQLDTQLHALNFPVFLIKELGFILSFVMLPMFFIDSFNGEYSSGAYRLILIRPQARKHL
                     LFAKWGSMAAITAIFLTVAYIFGHIAGWLLYSAPSTVTFYPDGPSYSILGAFGYSLLYY
                     LIFFLIYLALLGIASLISSIMPNAILAFFSTIATILATLYAPNTLQFFVMNSEITFQVL
                     NGMDQIPFFGSLFGIIIVTYSLVYGVWARKGWMT"
     gene            complement(6016..6843)
                     /locus_tag="BLV90_RS07665"
                     /old_locus_tag="SAMN05444487_106152"
     CDS             complement(6016..6843)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="BLV90_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106152"
                     /product="ABC transporter permease"
                     /protein_id="WP_091738760.1"
                     /transl_table=11
                     /translation="MISLIASEWQRIWSRKITWILFAAIPLVLFVTGHYYQGLNDNLKP
                     DSPEFALMDNFPILALAEQLLSVFNMTLLLLLVFSITEEYRTGQLRMVMIRSYTFTQLF
                     FAKWINVMIIMFLFNAFYFLLSYAFGSWMFDSSSHLMLFLHDDPVSNTSALLYNLRYYG
                     FAFLTLIAISAVITFFAVISQTTTTAIGLTLGYLLVSVGYSQFLHTFTQGLKPAINPAW
                     YFLSLTEIQYQGIALALADEPKLLFFNAGVLLVYTLIFGTGAYLLFTKKDRFI"
     misc_feature    6814..6830
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.88"
                     /tool="antismash"
     misc_feature    6907..6921
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.73"
                     /tool="antismash"
     gene            complement(<7089..7742)
                     /locus_tag="BLV90_RS07670"
                     /old_locus_tag="SAMN05444487_106153"
                     /pseudo=""
     CDS             complement(<7089..7742)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058380.1"
                     /locus_tag="BLV90_RS07670"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106153"
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNVLEAKNVTKRVGSRTLIDQMSFSIKKGQICGFLGPNGAGKTTL
                     IRLLTGLIHPTKGDLSINGISVTQNRTKALMNIGAIVESPIFFPYLTGRKALLNLARLH
                     PQLKGAQRKSRVKEVLEKVGLSHAADQKVGTYSLGMKQRLGIAQALLGNPSVIILDEPA
                     NGLDPMGMRELRSLILKLREETGISFFISSHLLDELQQLCDHLVVIKNGKLVWQG"
     misc_feature    7860..7876
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.94"
                     /tool="antismash"
     gene            8068..9237
                     /locus_tag="BLV90_RS07675"
                     /old_locus_tag="SAMN05444487_106154"
     CDS             8068..9237
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="BLV90_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106154"
                     /product="S53 family peptidase"
                     /protein_id="WP_091738765.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 8.7e-15, bitscore:
                     48.3, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSLWIKRGFLFLFGFLLVSYPFHTSYANEGDVNDVKSTLKINRS
                     HMAKKNGTSKAEVLDEIRGYTPFHIRKAYGLDQVKETGKGQHIAVVVAYGSPTIKKDLA
                     VFSEKFSLPKAKLKIYYPEGKPTETNPRWVTETAMDVQWVHAIAPKAKISLVVAKDKEI
                     PHLVKAIKLATALGANVVSNSWGSFEDEEAHKWDSTFSNKKVTYVASAGDYGKGILWPA
                     SARNVLAVGGTTLRMEQSGNFLSEVAWSGSSGGISAFTKRPAYQQLWAETLGDFRGVPD
                     VSFVGDPMTGAAVYSSTEIQGYKGWFLLGGTSLSTPCWSGIVALINEKRAKPLSSEQLV
                     KRLYALKDKGVYRDIVAGTNQEHSATVGYDLVTGLGSPIGASLIQELQK"
     gene            9419..9562
                     /locus_tag="BLV90_RS07680"
     CDS             9419..9562
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429839.1"
                     /locus_tag="BLV90_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_091738768.1"
                     /sec_met_domain="TIGR03731 (E-value: 2.9e-21, bitscore:
                     68.9, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 4.6e-12, bitscore:
                     39.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNKKDQFDLDVQVNKAKGDVEPQITSVSLCTPGCGETGSFNSY
                     CC"
     CDS_motif       9419..9493
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MANNKKDQFDLDVQVNKAKGDVEPQ"
                     /locus_tag="BLV90_RS07680_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9494..9562
                     /prepeptide="core"
                     /locus_tag="BLV90_RS07680_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="11.20"
                     /molecular_weight="2057.3"
                     /monoisotopic_mass="2055.9"
                     /core_sequence="ITSVSLCTPGCGETGSFNSYCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MANNKKDQFDLDVQVNKAKGDVEPQ"
                     /leader_location="[9418:9493](+)"
                     /alternative_weights="2075.4"
                     /alternative_weights="2093.4"
                     /alternative_weights="2111.4"
     gene            9604..9747
                     /locus_tag="BLV90_RS07685"
                     /old_locus_tag="SAMN05444487_106155"
     CDS             9604..9747
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429839.1"
                     /locus_tag="BLV90_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106155"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_091738768.1"
                     /sec_met_domain="TIGR03731 (E-value: 2.9e-21, bitscore:
                     68.9, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 4.6e-12, bitscore:
                     39.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNKKDQFDLDVQVNKAKGDVEPQITSVSLCTPGCGETGSFNSY
                     CC"
     CDS_motif       9604..9678
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MANNKKDQFDLDVQVNKAKGDVEPQ"
                     /locus_tag="BLV90_RS07685_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9679..9747
                     /prepeptide="core"
                     /locus_tag="BLV90_RS07685_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="11.20"
                     /molecular_weight="2057.3"
                     /monoisotopic_mass="2055.9"
                     /core_sequence="ITSVSLCTPGCGETGSFNSYCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MANNKKDQFDLDVQVNKAKGDVEPQ"
                     /leader_location="[9603:9678](+)"
                     /alternative_weights="2075.4"
                     /alternative_weights="2093.4"
                     /alternative_weights="2111.4"
     gene            9789..9932
                     /locus_tag="BLV90_RS07690"
                     /old_locus_tag="SAMN05444487_106156"
     CDS             9789..9932
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429839.1"
                     /locus_tag="BLV90_RS07690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106156"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_091738768.1"
                     /sec_met_domain="TIGR03731 (E-value: 2.9e-21, bitscore:
                     68.9, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 4.6e-12, bitscore:
                     39.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNKKDQFDLDVQVNKAKGDVEPQITSVSLCTPGCGETGSFNSY
                     CC"
     CDS_motif       9789..9863
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MANNKKDQFDLDVQVNKAKGDVEPQ"
                     /locus_tag="BLV90_RS07690_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9864..9932
                     /prepeptide="core"
                     /locus_tag="BLV90_RS07690_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="11.20"
                     /molecular_weight="2057.3"
                     /monoisotopic_mass="2055.9"
                     /core_sequence="ITSVSLCTPGCGETGSFNSYCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MANNKKDQFDLDVQVNKAKGDVEPQ"
                     /leader_location="[9788:9863](+)"
                     /alternative_weights="2075.4"
                     /alternative_weights="2093.4"
                     /alternative_weights="2111.4"
     gene            10001..13189
                     /locus_tag="BLV90_RS07695"
                     /old_locus_tag="SAMN05444487_106157"
     CDS             10001..13189
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="BLV90_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106157"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_091738771.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 7.3e-178,
                     bitscore: 586.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.9e-14,
                     bitscore: 47.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.5e-41, bitscore:
                     135.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASSLDTHRTHRKKKRSVYRPLDFFMFRSPLLPFDIFERLQQSDS
                     NRVLKELVQDPKIKEAIAIASPSLFVALGNLDSEDAKKKRQAETSIMRYLSRMATRSTP
                     FGILAGLTMGELGDYTEAQLNSSDHHMKRTRPDMEWLLSLVAKLEKRSDIIRQLRLTRN
                     HAVQYSGRRLILPFSSECGQQRNNDNDLRESINIQASEPVLQVLEAARESISFPDLLDH
                     LKGVYPDVDRDRIAGLIEQLFEQEYLISNLRPPMTNPSPLQYLIDQLDGIIEATAERQL
                     LLEIAQLIREYDALPIGQGLDQYLKLNEKMKDVVPSLSQVQVDMRVADQKISLHRQVGE
                     EVAKAAEILWRLSLPQRGVSHLKSYHKDFLEKYGTRREIPILELLNEETGLGAPSPYKR
                     PKSTRKDDDLPVFSKEKESILLELIQKALVTGSIEVEITDELLNRLEEIEIDEEEAPSS
                     MELYVEVMSSSKEAIDQGDYRVVMTPNAASHRISQSFGRFLDLFDENEVERIRSAVKRE
                     ENLYPNALIVEGNYLPPSGRVGNISLSPSLLKQELTIGTNAYSDERLTLDDVYVGASLD
                     RLYLKSPKHNKELIITSGNMLNFMNAPNVYRFMREVSIESVRNVQPFSWGEYDIGPFLP
                     RVTHGKTVIYLATWNINLERLGLKDAQVAPHLWNEALKRWRSEWMVPRYLYMTFADNRI
                     LLDLDHEDHVKQIQKELLTNKRVALKEHVGSIDDRWVTGVDGIYSQECLIPVEKYAETM
                     PESPVLYQYSAPLVVHKDRVRLPGTDWLYAKLYVSRSRQDDFIPQFMQEFADSMVESGA
                     AKDWFYMRYVDPEPHIRIRFRGVEEDLVSKLLPALSRWVDPLMSDGIIKRLMIDTYERE
                     VERYGGVHMIRDAEDVFAADSKLTTHLLKLSWNKEIDIPLVEVAALAIVDLLENFGLSY
                     EGQLKILDEIVDKDDYREEFRLRRRELMKLMDPRDNRKSLKEFRNGHVLNMLLKQRAPF
                     LAEFGEKVRAENPKLSLSNTPHQIIGSLIHMHCNRLMDVDRGKEVQALAFARHTLYSQK
                     YWRDKGREEHATNQ"
     aSDomain        10481..10765
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BLV90_RS07695_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="4.20E-15"
                     /identifier="RREFam001.1"
                     /label="BLV90_RS07695"
                     /locus_tag="BLV90_RS07695"
                     /protein_end="255"
                     /protein_start="160"
                     /score="47.2"
                     /tool="antismash"
                     /translation="TRNHAVQYSGRRLILPFSSECGQQRNNDNDLRESINIQASEPVLQ
                     VLEAARESISFPDLLDHLKGVYPDVDRDRIAGLIEQLFEQEYLISNLRPP"
     gene            13173..15038
                     /locus_tag="BLV90_RS07700"
                     /old_locus_tag="SAMN05444487_106158"
     CDS             13173..15038
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729073.1"
                     /locus_tag="BLV90_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106158"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_091738774.1"
                     /transl_table=11
                     /translation="MPQTSEINGATSPSFRNVMESFKFWPRILKLLWKTNPRYFIMVFG
                     LNGITSLIPAASVLLTQMLMTEVGIAKYTEVVQPVFIVFGLFAGMAIFREISRIISDNY
                     QAIYAELLSNSINILLMKKADLLPFKYFEDADAYDKLQRARQDSTFRPFQIFQQILQII
                     GGTITLLSVAGVLFYWQWWLALVLLLIPLTSSFSFLRVGEEEFQIDWKRAAERRKQSYF
                     LGLMTTDSSVKEVKVFGIGSLLLSKYQKLYDRFFREDKGLLLKRMRITLFFQVIGFLAV
                     IGTQLLVVQQTVAGVLTIATMMAYIQAIAQTQATSSSLLQTLFVMYQNNLYVSQLFEFL
                     DIEESEETIVQRPYISTKEKNDTGFVFQNVSFRYPGTDRYVLKNISFQLKPGETVAIVG
                     ENGSGKTTLVKLLVRLYELEEGDILYNGRSIRSYSVKEWRELLATVFQDFIRYEMTARE
                     NIALGNWRVAEEGEKVEFATKNSGATTVIEGLPHGLETQLGKWFKEGVQLSGGQWQKIA
                     IARAYMRDATLYVLDEPSAALDPKAEKEVFDKFAELTVDKMGIFISHRYSTVRNADRIV
                     FMQQGEILESGTHASLMKRNGSYAVLYQMQADAYVDSQEQQLNPA"
     gene            15095..16462
                     /locus_tag="BLV90_RS07705"
                     /old_locus_tag="SAMN05444487_106159"
     CDS             15095..16462
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="BLV90_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106159"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_091738779.1"
                     /sec_met_domain="LANC_like (E-value: 2.3e-68, bitscore:
                     224.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTVRELPTSRKVTLRKNAEQVLGVIADRLRNPEYIRKVALHPN
                     NVSSQAKAHPWGELSLSHGYPGTALLYGELDRFDPQAGWDQVAHQHLVAMQRYLEAEGF
                     QSISLFGGITGVAFATWSASREGERYGRLLEQLHTQIAESLRKQLRIERERRSKEKGVL
                     AQWYDIIVGITGVGRYLLIQKDQPELRELLDEILLDLVELSKPIVVERQTVPGWWIPQH
                     AQFTEHDRQSFAKGNFNCGLAHGIPGPLALLSLAKLQGVEVKGQVEAIQRMTQWLLQWK
                     QEDAYGSYWYDRVAWEEEVEGARLTHRHREAWCYGTPGVARALYFAGKALQDEGLKETS
                     VLAYQSIFKRPEILWDIDSPTICHGTAGLLEMTGQMYWDSNDRTLQIQRDYLLHRQLKD
                     FNPDSPFGYKDLEPQPIGYRGLDKVGLLEGAVGVALSLLSCVKGKGSGWSRSLLLH"
     gene            16492..17124
                     /locus_tag="BLV90_RS07710"
                     /old_locus_tag="SAMN05444487_106160"
     CDS             16492..17124
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014494.4"
                     /locus_tag="BLV90_RS07710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106160"
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="WP_091738782.1"
                     /sec_met_domain="Flavoprotein (E-value: 4.2e-30, bitscore:
                     97.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVPTQVLADKKLLVGMTGSIAVAGLPPYLAMFRSYFDQVRVIMT
                     YSAEQMIPPFTVSLFADEVYAPSMGKEPISHVELARWSDLFIILPATANVIGLVANGLA
                     TNLLTSTALASPQPLILYPNMNLLMWDKKAVQRNVQTIEEDGHTIIQPIRTNAYEIASR
                     SVRPNLLLPPSDQVLRDLIQVAQTRGKLVEPAQSATKSPSNPSIHSA"
     gene            complement(17365..17835)
                     /locus_tag="BLV90_RS07715"
                     /old_locus_tag="SAMN05444487_106161"
     CDS             complement(17365..17835)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012698.4"
                     /locus_tag="BLV90_RS07715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106161"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_091738918.1"
                     /transl_table=11
                     /translation="MIILAENLHHFPICEEISKRSGVKPIFIQSRQHFEALLHLLREGD
                     STPVTSKGEWIELAPDVRFDHRRHLIHRHGKVYPLSSTEYKIMQSLSSQLGTPCPTMEL
                     IDAVWGIHGHVGLDSLYVYIRRLREKIEDNPSRPQLLITHHGFGYELRSLVS"
     gene            complement(17891..18661)
                     /locus_tag="BLV90_RS07720"
                     /old_locus_tag="SAMN05444487_106162"
     CDS             complement(17891..18661)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="BLV90_RS07720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106162"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_091738785.1"
                     /transl_table=11
                     /translation="MKELFLSEWERIWARKKTIVSLIIYVALLGLFATWLHRGGIGFYT
                     PKLETSLNALNFPTFLLKETGFILALIMLPMFFVDSFNGEYSSGAYRLILIRPHSRGKL
                     LLAKWLSMAAVVAIFLSIAFIFSHILGQILYSAPNSITFYPDGDSYSAAGAFGYSLLYY
                     LTFFAIYLALLGIASLISSFLPNTILSFFLILATLLATFYTPDSYHYFILNGEAAFRVL
                     NGTDTTTFISSVLGIIVGTFILVYTYWKRRNWTM"
     gene            complement(18675..19502)
                     /locus_tag="BLV90_RS07725"
                     /old_locus_tag="SAMN05444487_106163"
     CDS             complement(18675..19502)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV90_RS07725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444487_106163"
                     /product="ABC transporter permease"
                     /protein_id="WP_143035018.1"
                     /transl_table=11
                     /translation="MMSLIASEWGRLWSRKVTWLLFALLPILMLVTGNYYHGKNDGIAP
                     GSPGYTTWDNFPVMALSDQLMTVFNMILLLLFVFSITEEYRTGQLRMVMIRSYSFTQLL
                     VAKWITIMSIMVLFHGLYFLLSYGVGGLFFDTSPHLYFAYYQDPIGGGPALTYTIRYYA
                     LAFLTLVAVSWLITFFAVVSQSTTTAIGVTLGFLLISFGYPQILQTFTKGLNPPLDAKW
                     YFISLTQIQTEGIALALGQTSKLLNFNAGVLFIYAFAFGTAAYLFFTKKDRFI"
     misc_feature    19566..19580
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 26.27"
                     /tool="antismash"
     gene            complement(<19748..20401)
                     /locus_tag="BLV90_RS07730"
                     /old_locus_tag="SAMN05444487_106164"
                     /pseudo=""
     CDS             complement(<19748..20401)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019421979.1"
                     /locus_tag="BLV90_RS07730"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106164"
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFVLEAKNVSKKVGSRTLINNMSFGVEKGQICGFLGPNGAGKTTL
                     IRLLTGLIQPTKGELAINGICVTKDRTKALMNLGAIVESPIFFPYLTGKKALLNLARLH
                     PQLPRTQRKAKVKEVLEKVSLTHAADQKVGTYSLGMKQRLGIAQALLGDPSVIILDEPA
                     NGLDPMGMRELRSLILQLREETGISFFISSHLLDELQQLCDHLVVIKQGKLVWQG"
     gene            complement(20490..20630)
                     /locus_tag="BLV90_RS16205"
                     /old_locus_tag="SAMN05444487_106165"
     CDS             complement(20490..20630)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV90_RS16205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444487_106165"
                     /product="hypothetical protein"
                     /protein_id="WP_177167950.1"
                     /transl_table=11
                     /translation="MKKSIIVIAMFSILTLGILIGNKTISNHYAGTVIDNPSGTERPGP
                     S"
     gene            complement(20800..22083)
                     /locus_tag="BLV90_RS07735"
                     /old_locus_tag="SAMN05444487_106166"
     CDS             complement(20800..22083)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024816.4"
                     /locus_tag="BLV90_RS07735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106166"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_091738794.1"
                     /transl_table=11
                     /translation="MEIGEKIRQLRIHKKMTQGQLVDGISSITYLSRIENGNIKPSQAF
                     IQSIAPRLGVQIEDLWGNNEESINRRIITIAKEFRKKQILTEEELSFLSLQANEIHSLE
                     IYLNIYTTLIDYYLKSNEDIDGAWRTYQLATKFIPRELNESLLKEFYYYYVVCGNLFYF
                     RQDFFMANQFYSSAEQFVELFNDPVEEARLSYNLSLVKDEIIEDKTVCIFYAQKAYNLY
                     SEQQYEQGIINSLIILGIQHHLHQNDEKALTYLHQAMELISSKDKLSQAYVEYNLGQVY
                     AGKEDEEKAIQHYLTSLELYDQIPSNHRKIYPYLRLIELFTRKKDWNLVEDYLQQALSL
                     VDPEKASLMHLKFLSIKANTYRLRDNELRYEKDMHKIIQLSIQKNQLKLVATFASELAN
                     HYYEKRAYKKAADYFVTAENYTKKMNLS"
     gene            22327..22980
                     /locus_tag="BLV90_RS07740"
                     /old_locus_tag="SAMN05444487_106167"
     CDS             22327..22980
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLV90_RS07740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05444487_106167"
                     /product="hypothetical protein"
                     /protein_id="WP_091738797.1"
                     /transl_table=11
                     /translation="MMDIDPALSWMSEGLKQISLAQQKPLFQVNMREKRGKNVSFLIEK
                     GQDTDKVQDSSYLIHKNTFAQMIYESFYNQGLTFNNLLPILIILNESQISGFYFPGFYR
                     YDKNEERFEFLREMDSEVEEKVQSFLQTNNIQSAVALGYALVNIDEIVSWDDVVVEIQT
                     AVKSFSQLIQLHGGLKETCLVPTLASGLKKPQPSDFFLSPILITHWIQPQYPLN"
     tRNA            23007..23080
                     /anticodon=(pos:170688..170690,aa:Cys,seq:gca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BLV90_RS07745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN05444487_106168"
                     /product="tRNA-Cys"
     gene            23007..23080
                     /locus_tag="BLV90_RS07745"
                     /old_locus_tag="SAMN05444487_106168"
     gene            complement(23247..23807)
                     /locus_tag="BLV90_RS07750"
                     /old_locus_tag="SAMN05444487_106169"
     CDS             complement(23247..23807)
                     /EC_number="2.1.1.63"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010493150.1"
                     /locus_tag="BLV90_RS07750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106169"
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="WP_091738800.1"
                     /transl_table=11
                     /translation="MRLTRTSVYWHSFIHPIFQNRPLYLASTDQGLCRITWPTESLETL
                     RTWVKKQIPDATLIESKKPLNAVIAQLEEYFAGNRESFTLPYDLFGTSFQTSVWNALAQ
                     IPYGETRSYSDIANTVGNPKAVRAVGTANGANPIPIVIPCHRVIGKSTALTGFRGGLKV
                     KEELLQLEGFHDYTKKGHARFQF"
     misc_feature    24542..24553
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     gene            24729..25103
                     /locus_tag="BLV90_RS07760"
                     /old_locus_tag="SAMN05444487_106170"
     CDS             24729..25103
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024556.4"
                     /locus_tag="BLV90_RS07760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106170"
                     /product="S-Ena type endospore appendage"
                     /protein_id="WP_091738806.1"
                     /transl_table=11
                     /translation="MSCCSSRATCPDPTSFQEAICGNFSTILAADNTVWKSYTSSGSSP
                     GPFYAMTLSVYADTTSLPVVVEVVTPAGPIILTPPGTEVTAGTTKSFTLLSVNTVNIHD
                     ITAGQLITGKYSITLYRSIF"
     gene            complement(25487..25840)
                     /locus_tag="BLV90_RS07765"
                     /old_locus_tag="SAMN05444487_106172"
     CDS             complement(25487..25840)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024556.4"
                     /locus_tag="BLV90_RS07765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106172"
                     /product="S-Ena type endospore appendage"
                     /protein_id="WP_091738809.1"
                     /transl_table=11
                     /translation="MNCEFGQVIRDEFCGKIYISGENESDHEILWESSLITPPTGTISV
                     YNERTSSDFLTFRIMHMKNQKTLSVSPGNSRSFTSSGLQSFQLVNIRAVTGMSQGTYSL
                     TIHYEFFLEPCND"
     gene            25931..26305
                     /locus_tag="BLV90_RS07770"
                     /old_locus_tag="SAMN05444487_106173"
     CDS             25931..26305
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024556.4"
                     /locus_tag="BLV90_RS07770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05444487_106173"
                     /product="S-Ena type endospore appendage"
                     /protein_id="WP_091738812.1"
                     /transl_table=11
                     /translation="MSCCSSRATCPDPTRFQEEICGNFSTDLGTDNTVWKSYTSSGSTP
                     GPFYVMTLNVYADTTSFPVVVEVVTPAGLIILTPPASEIAAGTTKSFTLLSVNAVNIHA
                     IAGGQRITGKYSITLYRNIF"
ORIGIN
        1 ctatgattac catgcaaatc gtatctccga tgtgatgtta gagacagctg gcactatgga
       61 tagagatgta gaaattaaat tcacattggg ctccatcaac tactctatcg atgtaaataa
      121 aaatcagctg gaagagttaa aggatcttta taagtcgtta attcgcatct cggaaatcac
      181 ctctgacaac gcggcttcct tgaactttgc aaaccaaagc ctagagttag catccgccgc
      241 actcggccga atgggcaaaa cagatgggaa cttggttgag gagtttacag gtatgaatca
      301 agttgccttt gactggttgg aagagactcg gttaagatat cggatcaagg atttcggttt
      361 tgtttttgag cgctatatta atatgtaatg gtaagtggat aaaaacaaga gaggtccttc
      421 aaacgaaggg gcctctcttg ttttttggaa gcatagcgga agagaaaata atttcgtaaa
      481 tgcgaacaaa tattcttgat agaacctcca cgggtaatat agggattgtt cccctccgaa
      541 cctcttcgtc atcagcgatg acagcggaga aacaggtagt aatatactat gttaccctag
      601 aaggtgaggt acagatggtg atatgccttt cttataccat acttagggtt attctatcaa
      661 agttttcgtc agaagggagt tggaaccaat atggctatga ataatggtgt tttaacaaga
      721 aaccagttgt taacagctgc atccaatata gtaagtgaaa aaggggtatc aaagcttacc
      781 cttgaggcgg tagcaaacca agcaggtgtt agtaaaggtg gattgttcta tcatttccct
      841 agtaaagaag atctagttca agcaatgatt gatgagttat ccgttgactt taagaatgat
      901 atgaaagata accttcaggc ctttcatgga aaagggcaat ggacccgagc ttatgtggag
      961 acgatgttca tgagggttga tgatggttta aagatgagtt cagcgctttt tgcttcgatg
     1021 tttaccaacc caaaattaat ggaaaaagcc caacttcagt ataaagggct tcaagaacag
     1081 atacagaatg atcaaataga ccccgtccat tcgactatcg caaggcttgc cgctgatggt
     1141 ttacggtttg cagaaatgtt tggactagca ccattggata aagaaacgag ggataaagta
     1201 cacggtgagt tgacgaaaat aataacaaag ggtggtatat aacgttttga tagaagccta
     1261 ccttttttac atgaggttta ggaagtaagt gaattagaaa ttgagttagt agggataaaa
     1321 atttaccttt ggcgggtagg ttttttcttt ttggagaagc ttaccctaaa tccaactaat
     1381 taccttgttt tacctgcaat aaaagccttg caataaaacc ggttaatcgg tatatttaat
     1441 ttgtggatca ctacttagaa tagaaagaaa aaagggttac cacaaaagag gaggaatgta
     1501 aagcatgaga aagaagattg gtgagaaaag tgtgaaaatg atgaaaatga tgactgtctt
     1561 cgctttggct ttagcttttg tcttcagtgg tggattcatt ggcccggtga aagcctcggc
     1621 tgcaccagac aatgagaaaa agctacccga aaagtatatt caaggatata agatcgataa
     1681 agatggtaaa aaaacaccgg tttataatac ggataacgca cccaaaggta aagttgcacc
     1741 aaaagcagat gaacccacta gtccatatgc ggccaattac cctaaattat ccgaagatcc
     1801 ctatgcgcct gcactggaaa gcggaacgac taaaactgac ccaccgggga aaataggaga
     1861 tatcgtatat tttaaactaa atggtgtaca agcacacttt aatgggtcag aggagttcac
     1921 agatgctgga gtttatttag aaaaaaaatc ggatggcacc attgaaaagg ggctctatga
     1981 agtgaaaaca ggtgcaacaa acactgcccc acttgagaaa ctaaatgagg agagggctca
     2041 gaacggcgaa gcatggatgg tagaaaaata tggaccatcg atggcttgga gtaaagcttt
     2101 tgatggaacc tccaagttaa aaagagagag caaatttaaa ttacttggaa caagcaccgt
     2161 tgccaattca gcagagtggt ggtctgggct agatattgaa catggtgtat cggaaacaga
     2221 atcatatagt cttgcatgga ctattggctt caagcttagt attgaagcag gtggcggttt
     2281 tgtaccaggg aaaacaacaa cagaatttag tacgcagtta acgaatacat ttggccaaga
     2341 gactactatt tcggataaag taacatataa agatcaaact aaagtaccaa aagctgataa
     2401 tccagcttat caatatgatg tctatcgagg agcattgtat caattaacga acacttatac
     2461 ccttgaacct ggaaccggtt tacaagaact gatcaacgct gaggaatttc cgggagactt
     2521 cggttttaaa caagggttgg ctaatccttc attccaatat aatagcaaag aactgtatta
     2581 tcccgtaaca ccgggttccc atcttggacc tgggggacaa taattccaaa aaaaacctag
     2641 ttaaaacaac ttctacttcc tattagcgat tgtaaaagcc cgatggttaa aaagtagagt
     2701 agcaggatag aaccctcgct actctacttt tttatggcct tcatcaccat tgacaatgta
     2761 ggtaggcttt tacctcttgg agcctttttt atctttgcga gcgggaaaat ctctaacttc
     2821 agcaatgggg gaaaaaagta gcgatagacg tcagactatc tttctgttct tttttcgctt
     2881 ctcatgggga gtgttttgac ctgagatggg tgtattaaat tccatccttt tttcgatgaa
     2941 tggaattgaa ctactttttc ttagccaaat gccactagct gataacaaac tagctaaccc
     3001 aatccagggg agggcatagg agttactcca gtccacgaac agtccaaaga aaaaaggtgc
     3061 catgatgatc gctacctgat tgattgttaa ggcgtagctt accgtcaaac caacggaatg
     3121 ttcttttgcc ttttcgccaa tttctacaat gtagaggctg taccatccga ctccaaaaaa
     3181 tcctagccat gaacagacta catatatgca ccaaataggt attttttctg gcaagaccac
     3241 caagaccacc aggccaacta cggacatcca taaaatcatc tctaagggtt taatacgatt
     3301 gcccttccat atcgtatcac ttaaccaggc taaggttatc cgaccaagca tgccgaataa
     3361 cagacaaaga gatagcatga atccagtgga aacgagtgtc atatgctcta ttttgctttt
     3421 tagataaagc atcaagtggg cgactaagac catttgaaat gatatgagag aaaaccccga
     3481 aaataatagt ggatagaggc ttttcttgcg agatagattt cgtagttctc caataaagtt
     3541 aacatgttgc gtgggtattt tactctcttt aacaggatct cgatagatta gaagaaacat
     3601 cagtccacct ataaaggctg atgaggcttg taattgaaca gcgattggcc aatcatatcg
     3661 aacgcttaac aatgggatca accaaccagc caatgctcct ccaatgggga tgccggcttg
     3721 acggatgcct gtagcaagtc ctcgctggga agaatcaaac cacttgatca cgactttgtt
     3781 accaccaggt tgtgcggtcc catagaaaat cccgactaat aaaagagtga ctaagagaga
     3841 cagataacta ctcagtagag aggatacccc catcgtaagt cccagcaaaa tcgacccgac
     3901 gcctacaatc catcgctctc catgctgatc taatgcacga ccaataaata acatcgacat
     3961 gagcggccca atattgacca tcgatataag caaacctacc tgtgcttgag atagtgaaaa
     4021 agtttgttgc catatagcag ctaacggtcc aaccccatag gttacaaagg tagcagtcgc
     4081 ttgagtccca gtggccaatc caaggaccat ccagcggaat ttttgcgaag aagatgaaaa
     4141 atacatagaa ttatactccc acgttaaatt atattgtctt cgtattttca agaagatatt
     4201 aatggtagtt taaatagggg agcgtatcct gtaaaattac tggttgtgat ctttcctatc
     4261 acaaaaaatg atctggaggt gctgttggtg gatattcgcg atctgcaaat tttccaaaca
     4321 gtatcccgcc ataaaagtgt gactaaagcg gcaaacgagc taaattatgt acaatccaat
     4381 gtcaccaatc gaattaatcg cttggaacag gagttaaacg cgcagttgtt tcaccggagt
     4441 gggaaaggga tgtcgttaac ttctgctgga agaaatctca tccaatacgc ggatccgatt
     4501 ttagagatgg tgaatgaggc aaaaaatgcg tttcttattc cccaaggtcc attaaaattg
     4561 ggctctaccg aatcaactgc cgcggttcat cttccctcgt tattaatgaa gtatcatgaa
     4621 gcttatccgc aagtggatgt atccttgacc accgcttctt ctgaagagtt aataaaacga
     4681 gtgctgcatt atgaattaga tggcgttttt gttgttggcc ctatcaatca cccagagtta
     4741 aaagcattca cctttatgga agaagagcta gtgttgattt catctccgca tcatcctcct
     4801 attcattcag caagggatct tcaacatgag accctactcg tttttgatgt gggatgttcc
     4861 tatcgttcca ggttggaaca gtggttaagc gatgagaagg cccattcggt taagaggatg
     4921 gaattgagca cgttagaggg attgtttcgt tgtgtagaat ctggttttgg agttgcttta
     4981 gtaacgcgat cagtagcaca agaatataaa cgtggagaaa taaaactcca tcccctctcg
     5041 acggattatc atcagtccac gaccgttttc atccaacgaa aggatcgtta tcaatctcct
     5101 gcattgagcc gattggtaga gttgatggag aatgagtgaa aggatatata caaaaacctc
     5161 tctattgatg agctacttct gtgtggaagt aatcatcata gagaggtttt attatcctat
     5221 cgctgtaatc tatgtcatcc aaccttttcg tgcccagaca ccatacacca agctgtaagt
     5281 gacgatgatg ataccaaata atgagccgaa gaaggggatt tgatccattc cattaagtac
     5341 ttgaaaggtt atttcactat tcatcacaaa aaattgaagg gtgttaggtg catacagtgt
     5401 agctaaaatc gtagcgatgg tcgaaaagaa agcgagaata gcattgggca taatggagct
     5461 aattagactg gcgataccaa ggagggcaag gtagatcaag aagaagataa ggtagtaaag
     5521 aagactataa ccaaaggctc ctaggatgga gtaggatgga ccatcagggt agaaagtgac
     5581 ggtacttgga gctgagtata aaagccatcc ggcgatgtgg ccgaagatat aggctacggt
     5641 aagaaagata gcggtgatag ctgccataga accccatttg gcaaacagga gatgctttct
     5701 agcttgcggg cgaatgagga tcagacggta agcccctgaa ctatattccc cgttaaaact
     5761 atctataaaa aacatgggga gcatgacaaa ggagagaatg aatcctaact ccttgattag
     5821 aaagacaggg aagttcaatg catgaagttg tgtatcaagt tgggctgtgt aaaagccgat
     5881 accccctcgg tggagcaaga aggtggacat tcccaatagt aggatgaaga tccctaagct
     5941 gaccatcgtt ttacgacgtg cccaaatacg ctcccactca ctcataaata actcgctcaa
     6001 tgatgattcc tccctttaaa taaaacgatc ttttttggtg aagagaaggt aagcgcctgt
     6061 gccaaaaatc aaggtgtata caaggagaac ccctgcatta aagaagagta actttggttc
     6121 atcagccaga gccaacgcaa ttccctgata ttgaatctcg gtgagggaga gaaagtacca
     6181 ggcaggatta atggccggtt ttaatccctg ggtaaaggtg tgtaggaatt gagaatagcc
     6241 aacggagaca agtagatagc caagagtaag gccgatggct gtggttgtgg tttgactgat
     6301 gacagcaaaa aaggtgatga ccgcagaaat ggcaattagt gttaaaaagg caaagccata
     6361 gtaacgcagg ttgtataaca aagctgaggt attagagacg gggtcatcat gtaagaagag
     6421 catcaggtga gaggaactat caaacatcca gcttccaaaa gcatagctga gaagaaaata
     6481 gaaggcatta aagaggaaca tgatgatcat cacattgatc cacttggcaa aaaataattg
     6541 agtgaaggtg tacgaacgga tcatgaccat gcgaagttgc cctgtgcgat attcctcagt
     6601 gatagagaat acgagcagga ggagaagcgt catattaaag acggataaca gttgttcggc
     6661 gagggcgagt attgggaaat tatccatcaa ggcaaattcg gggctgtctg gctttagatt
     6721 atcgttcagc ccttgataat agtgaccagt aacaaagagg acgaggggga tggccgcaaa
     6781 taagatccag gtgattttgc gactccagat acgttgccat tcacttgcaa tcagggagat
     6841 catgagctca tcatctcaac gaaggcgtct tccagacgct tttgtttttt ctctacacta
     6901 agtatttgga tgccattttc aattaagtgg gtgtttaaga tagcgagatc ctcttcatgg
     6961 atctccacgt atatttgatt tccttcgata tgatcgacag ggtagtgctt cttaatgaac
     7021 ggagcggctt tatcaattgg agtgagggtg aaggcataaa ggggttttcc tgagaggctc
     7081 tccatctcac cctgccacac taattttcca tttttgataa ccacgagatg atcacataac
     7141 tgttgcaact catctaaaag gtgactggag atgaaaaagc tgatcccggt ttcttcccgc
     7201 agttttagga tgaggctacg caattcccgc atccccattg gatccaatcc attggcgggt
     7261 tcatcaagaa taatcactga gggattaccg agcagtgctt gggcgattcc gagacgttgt
     7321 ttcattccta gcgaataggt tcctactttt tgatctgcag catgggagag tcctactttc
     7381 tccaacactt ctttcacgcg actttttcgt tgtgctcctt ttaattgagg atgtagtcgg
     7441 gccaggttga ggagtgcttt tctcccagtt aggtagggga agaagatggg ggactctaca
     7501 atcgctccga tgttcatcag tgccttggta cgattttgcg taacactgat gccgttgatg
     7561 gaaaggtctc ctttggtagg gtggataagc cctgttaata atcggatcag ggttgtttta
     7621 cctgcaccat tggggccaag gaaaccgcag atttgtcctt tttttatgga gaaggacatc
     7681 tgatcgatca aggtacgaga gccgacgcgc ttggtaacat tttttgcctc taaaacattc
     7741 atcctatcac tcctcatagg gtggtttaat ttatttgtcg tattagtgta ctaatcaaac
     7801 agtacaatat tgtattagcg taataataca cgatggcgga taaatctgtc aactgttttt
     7861 tgtaactttt tttccgaaaa aaggattcta ccttctagtg ttatcgagta gatccgctat
     7921 ggtaggtcta tttactagaa gaaaaggcat cgttttatta gatgaaaaat tgctaacttt
     7981 actactattt tttaaccttc cagattgaat atggttagag atgaattgag gaatgtgcct
     8041 tgattactta aaagaaagga cagataaatg aaatcattat ggataaaacg aggttttctc
     8101 tttctattcg ggtttctact agttagttat ccctttcata ccagttatgc caatgaaggg
     8161 gatgtaaacg atgtaaagtc cacgttgaaa atcaatcgta gtcatatggc caaaaagaat
     8221 ggcacatcca aagcagaagt gttggatgag attcggggct ataccccttt tcatattcga
     8281 aaagcgtatg gtctggatca agtgaaggaa acgggaaaag gacaacatat cgcagtcgtc
     8341 gtcgcctatg ggagtccaac gataaaaaaa gatcttgctg tgtttagtga gaagtttagt
     8401 ctgccaaaag caaagctgaa gatttattac ccagagggaa agccaacaga aacaaacccc
     8461 cgttgggtca cagagactgc catggatgta cagtgggtac atgccatcgc tcccaaagct
     8521 aaaatctccc tcgtcgttgc taaggataag gagattccac atttagtaaa ggcgataaag
     8581 ttagctactg cactaggggc caatgtcgtt tctaatagtt ggggttcctt tgaggatgaa
     8641 gaggcacaca aatgggactc tacttttagc aacaaaaaag tgacctatgt cgcctcagca
     8701 ggtgattatg ggaaagggat attgtggccg gcctctgcac gcaatgtact ggcagttgga
     8761 gggaccaccc tccgtatgga gcaaagtggt aattttctta gtgaggttgc ttggtcaggt
     8821 agtagtgggg gaattagtgc ctttacaaag agacccgctt atcaacaact atgggcagaa
     8881 acattgggtg attttcgagg tgttcccgat gtctcctttg taggagatcc tatgacaggc
     8941 gcggctgtgt actcttcgac ggagatccag gggtataagg gttggtttct acttggtggg
     9001 acaagcttat ccaccccttg ttggtccggt atcgtcgcat taattaatga gaaacgagcc
     9061 aagcccttaa gcagtgaaca gctggtgaaa aggttgtacg cgctaaagga taaaggggtg
     9121 tatcgggata tcgtagcagg cactaatcaa gagcattcgg ctactgtggg gtacgatctc
     9181 gtcacagggc ttggtagtcc aataggtgct tcattaattc aggaactaca aaaataataa
     9241 aggtcactaa aaacaacagg aaacaagcgg atttcctgtt gtttcaaaag aaaaccttac
     9301 agaatgttta tgttaattaa gtaaattact agctcatttt caggtaaata gattcttatc
     9361 catataagat aaacacgaag ggacaacaaa aacgccccct gagaggaagg agtaaaaaat
     9421 ggcaaacaac aaaaaagatc aattcgacct agatgtacag gtgaacaaag caaaaggtga
     9481 tgtagagcca caaatcactt ccgtttcctt gtgcaccccc ggttgcggcg aaaccggttc
     9541 attcaacagc tactgctgct aaccacctaa tcactactaa ctaatttgag gaggaatata
     9601 accatggcaa acaacaaaaa agatcaattc gacctagacg tacaggtgaa caaagcaaag
     9661 ggcgatgtag agccacaaat cacttccgtt tccttgtgta cccccggttg cggcgaaact
     9721 ggttcattca acagctactg ctgctaaccg cctaatcacc actaactaat ttgaggagga
     9781 atacaaccat ggcaaacaac aaaaaagatc aattcgacct agacgtacag gtgaacaaag
     9841 caaaaggcga tgtagagcca caaatcactt ccgtttcctt gtgtaccccc ggttgcggcg
     9901 aaaccggttc attcaacagc tactgctgct aataaaagga aaagaggcgg aacatctgaa
     9961 aggatgttcc gtttctacta catatgaagg aggtaagaat atggcttcat cacttgatac
    10021 tcatcggacc catcgcaaga aaaaacggag tgtttatcgt ccgcttgatt tttttatgtt
    10081 tagaagccca cttttaccct tcgatatctt tgaacgatta caacaaagcg attccaatcg
    10141 tgttttgaag gaattggtac aagatccgaa gattaaagag gcgattgcca ttgcaagtcc
    10201 atccttgttt gtggcactag gtaatctaga tagtgaagat gcgaagaaga aacggcaagc
    10261 ggagacaagc atcatgcgtt acttatcccg catggctaca cgatccaccc catttgggat
    10321 tttggctggc ctaactatgg gggagttggg ggattatacc gaagcacaat tgaactcatc
    10381 ggatcatcat atgaagcgca ctcgtcccga tatggaatgg ctactctccc ttgtagcaaa
    10441 gttagagaaa cgttccgata taattagaca gcttcgcctt actcgtaacc atgctgtgca
    10501 atatagtgga cgtcgcctca tccttccttt ttcatccgag tgtggtcaac agcgcaataa
    10561 tgataatgat ctgcgtgagt ccatcaatat tcaagcttct gaacccgtgc tacaggtgct
    10621 tgaagccgca agggagtcta tttcctttcc tgacctcctc gatcatttga agggcgtgta
    10681 tcctgatgta gatcgtgaca gaatcgctgg tttaattgaa caactctttg aacaggaata
    10741 tctcattagt aatctacgac ctccgatgac caacccttct cctctgcaat atctgattga
    10801 tcagttagat gggatcattg aggcgacagc agaacggcaa ttgttgctag aaattgcaca
    10861 attaatccgt gaatatgatg ccttacccat cggtcaagga ctggaccaat atttaaagct
    10921 gaatgaaaag atgaaagatg tcgtgccaag cctttcccaa gtacaggtcg atatgcgagt
    10981 ggcggatcaa aaaattagcc ttcatcgaca agtaggggaa gaagtggcaa aggcggcaga
    11041 gattctgtgg cggctctctc ttccacaacg gggagttagt catttgaaaa gttatcataa
    11101 ggacttttta gagaagtatg ggacgaggcg cgagatcccg atattagaac ttctcaatga
    11161 agagactggt ttaggtgccc ccagtccata taagcgcccc aaaagtacac ggaaggatga
    11221 cgatctacct gtcttttcaa aggaaaagga atcgattcta cttgagttga tccaaaaagc
    11281 acttgtcaca ggatcgattg aagtggaaat cacagatgag ttattgaatc gacttgaaga
    11341 aatcgagatc gatgaagaag aggccccatc ctcgatggag ttatatgtag aggtcatgtc
    11401 ctcttcaaag gaagcgatcg atcaagggga ttaccgtgtc gtaatgacac ccaatgcagc
    11461 ttcccatcga attagtcaat cctttggaag gttcttagat ctctttgatg agaatgaagt
    11521 tgagcggatt cgcagtgcgg taaagcgaga ggagaatctg tatcccaatg ccctgatcgt
    11581 cgaagggaat tatctccctc cttccgggag agtcgggaat atatccttga gtccttcgtt
    11641 gttaaagcag gaattaacga ttggcaccaa tgcctatagc gacgagcggt tgaccctgga
    11701 tgatgtatat gttggggcat cccttgatcg tctataccta aagtcaccta aacataataa
    11761 agaattgatt attacctcgg gtaatatgct caattttatg aacgcaccca atgtgtatcg
    11821 attcatgagg gaagtatcga tcgaaagtgt gcgcaatgta cagccattct cctggggaga
    11881 gtacgatatc ggtccattcc taccaagggt tacccatgga aaaaccgtga tatatctggc
    11941 tacctggaat atcaatttgg agcgattggg tcttaaggat gcgcaagtag ctccccactt
    12001 atggaatgaa gcgcttaagc gttggcgttc agagtggatg gttccacgct acctctatat
    12061 gacctttgcc gataaccgaa ttctattgga tctcgatcat gaagatcatg tgaagcagat
    12121 ccaaaaagaa ttgctaacca ataaacgagt ggcattgaag gaacatgtag gctcgattga
    12181 tgatcgttgg gtgacaggtg tcgatggaat ctattcacag gagtgtctca tccctgtgga
    12241 aaaatacgcg gagacgatgc cggaaagtcc agtcttgtat cagtattcgg caccgctagt
    12301 tgttcataaa gaccgggtgc gtctaccagg aacggattgg ttatatgcca agttgtatgt
    12361 gtcacgaagc cggcaggatg attttatccc acaatttatg caagagtttg ccgactcgat
    12421 ggtggagagt ggcgctgcaa aagattggtt ctatatgcgt tacgtcgatc ctgaaccgca
    12481 tattcgtata cgattccgtg gtgtcgagga ggatttggtc agtaagctac tccctgcact
    12541 aagtcgttgg gtggatccat tgatgtccga tggaatcatc aaacgactga tgatcgatac
    12601 ctatgaacgg gaagtggagc gttatggcgg cgttcatatg attcgggatg ctgaggatgt
    12661 gtttgcggcc gacagcaaat taacaaccca tttacttaaa ttaagttgga ataaagagat
    12721 cgatatcccc ttggttgaag tagcggcact ggcgattgtg gatctgcttg agaattttgg
    12781 cctttcctat gagggtcagc taaaaatcct cgatgaaatt gtggataaag atgattatcg
    12841 tgaggagttc cgtctccgac gtcgagaatt gatgaaactg atggatccgc gggataatcg
    12901 gaaatcgctt aaggaattcc gcaatggtca tgtgcttaac atgttactga agcagcgggc
    12961 tccgtttttg gctgagtttg gtgagaaggt gagagcagaa aatcccaagc tttctctatc
    13021 caacacccca catcaaatta ttgggagttt gattcatatg cattgtaacc gtctgatgga
    13081 tgtagatcga ggcaaagaag tacaagcact tgcctttgcc cgtcatactc tctatagcca
    13141 aaaatactgg agagataaag gaagggaaga gcatgccaca aaccagtgaa ataaatgggg
    13201 ctactagccc ctcttttcgc aatgttatgg agtcttttaa gttttggcca cgcatcttaa
    13261 agctcctttg gaaaaccaat cctcgctact tcatcatggt gtttgggtta aatgggatca
    13321 ccagtttgat tccagcggct agcgtattgt tgacacaaat gctgatgaca gaagtaggca
    13381 ttgctaagta tacagaagtg gttcaaccgg tttttatcgt atttggttta tttgctggca
    13441 tggctatctt tcgagaaatt agccggatta tcagtgataa ttatcaggca atctatgcgg
    13501 aactgctgag taattccatc aacatcctat taatgaaaaa agcagatctc ctcccgttta
    13561 aatacttcga ggacgcggat gcatacgata aattgcaacg ggcaaggcaa gattctacct
    13621 ttcgtccctt tcagattttc cagcagatcc tccaaatcat cggcggtacc atcaccttgt
    13681 tgtcggtggc aggagtgctg ttttattggc agtggtggct agcattggtc ttgctactga
    13741 tccctttaac ttcttctttc tcctttttgc gagtggggga agaagagttt caaattgatt
    13801 ggaaacgagc agcagagcgt cggaagcagt cctatttttt gggtctgatg acgacggatt
    13861 cctcggtaaa agaagtgaag gtatttggga ttggctcatt gcttttaagt aaataccaaa
    13921 aattgtatga tcgttttttc agggaagaca aagggctttt gcttaagcga atgcgaatta
    13981 ccttgttctt tcaggttata ggttttttgg cggtcattgg tactcaattg cttgttgtac
    14041 aacaaaccgt tgctggagtt ttgaccatcg ccacgatgat ggcgtatatt caagcgattg
    14101 ctcagactca agcgacatcc tcctccctct tacaaacgct ttttgtgatg taccaaaaca
    14161 atctttatgt gagtcaattg tttgagttcc tagacattga agaatcagaa gagacgattg
    14221 tgcagagacc ttatatctct actaaggaga agaacgatac ggggtttgtc tttcaaaatg
    14281 tctctttccg ttatcctggg acggatcgtt atgtactaaa gaatattagc tttcagctaa
    14341 aacctgggga gacggtagcc atcgtcggtg aaaatgggtc cggtaaaacg acgctcgtga
    14401 aactattggt tcggctttat gaattggagg agggcgatat tctttacaat ggtcgttcca
    14461 tccgttccta ctcagtaaag gagtggcggg aactattggc gactgttttc caggatttca
    14521 ttcgttatga aatgaccgcc cgtgaaaata ttgcccttgg gaattggcgt gtggctgaag
    14581 agggagaaaa agtagagttt gctacgaaga actctggagc aaccaccgtc attgagggtt
    14641 tgccccatgg attagaaacc caactaggca aatggtttaa ggaaggggtg caattatccg
    14701 gcggacaatg gcaaaaaatt gcgattgcac gagcgtatat gcgtgacgca accctctatg
    14761 tcttggacga gcccagtgca gcgctggatc caaaggcaga gaaggaagtc tttgataaat
    14821 ttgctgagct aactgtggat aagatgggga tctttatttc acatcgctac tccaccgtgc
    14881 gcaatgccga tcgtattgtt ttcatgcaac aaggggagat cttggaaagc ggcacccatg
    14941 cctccctcat gaagcgaaac ggttcctatg cagttctcta tcaaatgcaa gcggatgcgt
    15001 atgtagattc tcaggagcaa cagttaaatc cagcttaaat caatgaatac tacttccact
    15061 gttaaatcaa agtctctggt aaggagggaa taacatggcg acaactgtgc gagagttacc
    15121 aacgagcaga aaagtgacgt tacgaaaaaa tgccgagcag gtactgggtg tgattgcaga
    15181 tcgtttgcgt aatccagagt acattcggaa agtagctctt catccgaaca acgtttccag
    15241 tcaggccaaa gctcatccat ggggagaatt atccctctcc cacggttacc caggtacggc
    15301 gctattgtat ggggagttag ataggtttga ccctcaagca ggttgggatc aggtagccca
    15361 tcagcattta gtagccatgc aaaggtattt ggaagcggag ggttttcaga gcatttcttt
    15421 gtttgggggg attacaggtg ttgcctttgc cacctggagt gcttcccgag aaggtgagcg
    15481 ttatggccgt ttattggaac aactccacac ccagattgcc gagtcattac gaaaacaatt
    15541 aaggattgaa agagagagac gctcaaagga aaaaggagtg ctcgctcaat ggtacgacat
    15601 catcgtcgga attaccggag taggtagata tctgctcatc cagaaggatc aaccggagtt
    15661 gagggagtta ctggatgaga tcctacttga tttggttgaa ttatccaaac ctattgttgt
    15721 ggagcgacaa acggttccag ggtggtggat cccccagcat gctcaattta cagagcatga
    15781 ccgtcaatcc tttgcaaaag ggaactttaa ctgtggtctc gcccatggta ttccgggtcc
    15841 tctcgcccta ttatccttag caaagcttca gggcgtcgag gtaaagggcc aggtagaggc
    15901 gattcagcgc atgacacagt ggctcctgca gtggaagcaa gaagatgcct atggttccta
    15961 ttggtatgat cgcgttgctt gggaggaaga agttgagggg gctcgcttaa cccatcggca
    16021 tcgtgaagca tggtgttatg gaactccagg agtggcacgg gcactctatt ttgcgggaaa
    16081 agcattgcag gatgaaggat taaaagagac cagtgtgttg gcctatcaat ccatctttaa
    16141 acgtcccgaa atcttgtggg atattgactc tcctaccatt tgtcatggaa cagctggtct
    16201 cttggagatg acagggcaga tgtactggga tagtaatgat cgtaccttac aaatccaacg
    16261 ggattacttg ctccatcggc aattaaaaga ttttaatccg gactccccct ttggatataa
    16321 agatttagag ccccagccga ttgggtaccg gggtttagat aaagtgggct tgctagaggg
    16381 tgccgtaggg gttgccctat ctctgctctc ttgtgtgaaa ggaaaaggaa gtgggtggag
    16441 ccgttccttg ttactccact aacagaaagg tagctagaag gaggatgaaa aatgcaagtt
    16501 cctacccaag tactcgcgga taagaaactg ctggtaggga tgacaggatc gatcgcggtg
    16561 gctggtttgc caccgtatct cgctatgttt cgctcctatt ttgatcaggt acgagtcatc
    16621 atgacatact cagcagaaca gatgattcca ccctttacgg tatcgttgtt cgcagatgag
    16681 gtatatgctc cctccatggg gaaagagcct atcagccatg tcgaattggc tagatggtcc
    16741 gatcttttta ttattttgcc agcaacggcc aatgtgattg gtctagtagc caatggactg
    16801 gctaccaact tgttaacctc caccgcttta gcatccccac agccgcttat tctgtatcca
    16861 aacatgaatt tgttgatgtg ggataaaaaa gcagttcaac gaaatgtcca aaccatagaa
    16921 gaagatggcc ataccattat tcaacccatc cgtaccaatg cttatgagat cgcctcccgc
    16981 agtgttcgtc ccaacctgtt attaccgcca tcggatcaag tgcttcgtga tctcatccag
    17041 gtggctcaga cgcgggggaa actagtagaa cctgcacaat cagcgacgaa atcgcctagt
    17101 aatccatcga ttcacagtgc gtaagattgt agagtcgtag attttcaaaa agatagttga
    17161 ggagggagct taaattgctc tctctttaat ttgaagtgtg tatgtggtgt atgtgacgaa
    17221 gcgatcaatc agggcccatc tatcgaagga agttacctaa gtgctatttc aacaagaaaa
    17281 gggttgttcc cttgcacaac cttgtgcgag agaacagccc tttaacctta ttattgtgat
    17341 tagctaggat aagttgaaat ttgttcagga tactagtgat cgaagttcat acccaaatcc
    17401 gtggtgggtg atgagcaatt gggggcgact agggttgtct tcgatcttct cgcgtaatcg
    17461 acggatatag acgtaaagac tatctaatcc gacatgacca tgaatgcccc aaactgcatc
    17521 aattagttcc atcgttgggc atggagttcc taactgagaa gatagagatt gcataatttt
    17581 atactctgta ctggataagg gatatacttt tccatgacgg tggataaggt gtcgacgatg
    17641 gtcaaaccga acgtctgggg ctagttcaat ccattccccc ttggatgtaa caggagtgga
    17701 atcaccttcc cttaagagat gaagcaatgc ttcgaaatgt tgccgtgatt gaatgaagat
    17761 gggctttaca cccgatctct ttgaaatctc ttcgcaaata gggaagtgat gaaggttttc
    17821 tgccaagatg atcatgtcac tcacagtctg ccacctccca tggatgtgaa tttcaatagg
    17881 gtagaatcga ttacatggtc cagttgcgac gtttccagta ggtatagacg aggataaacg
    17941 ttccaacgat gattcctagc acagagctga taaaggttgt tgtgtcagtt ccgttgagaa
    18001 cgcggaaagc agcttccccg ttgaggatga aatagtgata gctatctggg gtgtaaaatg
    18061 tagccagtag tgtagcaagg attaagaaga aagatagaat cgtattggga agaaaggagc
    18121 taatcaagct agcaattccc aacagggcaa ggtagatggc gaaaaaagtg agatagtaga
    18181 gaaggctata accgaaggcc ccagctgccg agtaagaatc accatctgga taaaaggtga
    18241 tcgagttagg tgcagagtag agaatctggc ctaggatatg gctaaagata aaggctatgc
    18301 taagaaaaat cgcaacaaca gcggccatcg aaagccattt ggcaagtaat agttttcccc
    18361 gagaatgggg acggatcaaa atgaggcgat aagctcctga gctatactcc ccattaaagc
    18421 tatccacaaa aaacatgggg agcataatca aggcgaggat aaagccagtc tcttttaaga
    18481 gaaaggttgg aaagttaaga gcattgaggg aggtttctaa ttttggcgta taaaagccaa
    18541 ttccgccccg atgaagccaa gtagcgaata atcctaataa tgccacatag atgatgaggc
    18601 ttacgattgt cttttttcgt gcccagatac gttcccattc gctaagaaaa agctctttca
    18661 tatgtcagcc tcctttagat aaagcggtcc tttttggtga agaaaagata cgcggcagtc
    18721 ccgaaggcga aggcgtagat gaaaaggaca cctgcattaa agttgagtaa cttggatgtt
    18781 tgtcccaggg ccaatgcgat cccttccgtt tggatctgag tgagagaaat aaaataccat
    18841 ttggcatcaa ggggcgggtt gagtcctttg gtgaaggttt gtaaaatctg aggatatcca
    18901 aaggaaatga gcagaaaccc taatgtgaca ccaatggctg tggtggttga ttgactgacg
    18961 acagcaaaga acgtgatcag ccaggagacg gctactaagg ttaagaaggc gagagcatag
    19021 tagcgaatcg tgtaggtgag agcagggcca ccacctatag ggtcttgata gtaggcgaaa
    19081 taaagatgtg gtgaagtgtc aaagaacaaa ccgcctacgc cataactgag aagaaagtag
    19141 aggccgtgaa agagtaccat gatactcatg atggtgatcc atttggcaac caatagctga
    19201 gtaaaggaat aggagcgaat catcaccatc cgtagctgac ctgtacgata ctcctctgta
    19261 atggagaaaa cgaaaagaag gagtaagatc atattaaata cggtcatgag ctggtctgag
    19321 agagccatga ctgggaagtt atcccaagtg gtataacctg ggcttcctgg tgcaatgcca
    19381 tcattttttc catgataata gttaccagtg accaacatga gaatgggcag aagcgcaaaa
    19441 aggagccatg ttacttttcg actccacaat cgcccccact cacttgcaat cagggacatc
    19501 atgaggacac catctcgatg aaggcgtctt ctagacgctt ctgttttttc tcaacgctga
    19561 ggacttgaat ctcattttca atcaaaacct tgttgagttc accgatctca tcctcactga
    19621 tttccacatt gagttgattc tttgaaattc gctgtacggg gtagctttgt tgaatcagtt
    19681 tctgggcttt atctacagga gagagagtat aagcgaagag cggtgtgcca gaaatatccc
    19741 cgagctcccc ttgccagacg agcttgccct gtttaataac aacaaggtga tcacatagtt
    19801 gttgcaattc atccaataga tgactagaga taaagaagct gatcccggtt tcttcgcgta
    19861 gttgtaagat aaggctacgc aattcccgca tacccatcgg atcaagtcca ttcgcaggtt
    19921 cgtcaagaat aatgacggaa gggtcaccga gaagagcttg ggcgataccc aggcgttgtt
    19981 tcatcccgag agagtaggtg cccacctttt gatccgcggc atgagtgagg cttaccttct
    20041 ccaatacttc ttttactttt gccttacgtt gtgtccgtgg caactgtggg tgcaatcgag
    20101 ccaagttgag cagcgctttt ttacccgtta aataagggaa gaagattgga gattctacga
    20161 tcgcacccag attcatcaat gccttagtgc gatccttggt gacacaaatt ccattaatcg
    20221 cgagctcgcc tttggttggt tgaatcaatc cagttaaaag gcgaatcagt gttgttttac
    20281 cagcaccgtt gggaccaaga aacccacaga tttgaccttt ttcaacaccg aaggacatgt
    20341 tgttaattag cgtacgtgag ccaactttct tggacacgtt tttagcttct aaaacgaaca
    20401 tttgatcact ccttataaat ctgtaatgca tttcttttat tatgtttaat aaaaagattt
    20461 gttattgtac gtttctgata tccagagatt tagctggggc caggtctctc agtgcctgat
    20521 ggattatcaa ttactgtacc agcgtagtgg ttggatatcg ttttattacc aataagaatt
    20581 cctagagtta gaatggagaa catggcaata acgatgattg actttttcat gattaatcct
    20641 cctacatttt gaagtgcgtt tgtcttgaat taagaataca gcttaagaga ggttcaatat
    20701 aataagtaaa ataggatgat ttttatgagg ggtttcttac tggaattatc attaaattta
    20761 aacaaaaaaa gacggtgaga agtgcctgta ttcaccgaat taagataaat tcattttttt
    20821 agtgtaattt tctgcggtta caaaataatc tgctgccttt ttatatgctc tcttctcata
    20881 gtagtgattt gctaattcac tagcaaaagt agccactaat tttaattggt tcttttgaat
    20941 acttaactgg ataattttat gcatgtcctt ttcgtatcgc aattcattgt ctcgtaagcg
    21001 ataggtgttg gctttaatag atagaaattt tagatgcatc aatgaggctt tttctggatc
    21061 tactaatgag agagcttgtt ggaggtagtc ttcgacaagg ttccaatcct ttttacgtgt
    21121 gaagagttcg atgagacgaa gataagggta gattttgcgg tgattgctag ggatttgatc
    21181 gtataattcg aggcttgtaa gatagtgttg aatcgctttc tcctcgtcct ctttaccagc
    21241 atagacctga cctaggttgt attccacgta agcctgtgag agcttgtcct tagatgatat
    21301 aagctccatg gcttgatgaa gataagtaag ggctttttca tcgttttgat gtaagtgatg
    21361 ttgtattcct aatataatca agctgtttat gatgccctgc tcatattgct gttcactgta
    21421 aagattataa gccttttgag cataaaagat gcaaaccgtt ttgtcttcta taatttcatc
    21481 tttgactaga cttaaattat aagatagccg tgcttcttct actggatcgt taaacaattc
    21541 cacaaactgt tcagcagaag agtaaaattg atttgccata aagaaatcct gtctaaaata
    21601 aaacaggttt ccgcaaacta catagtaata gtagaattcc ttcaataaag actcattcaa
    21661 ttcgcgtgga ataaacttag tagctagttg ataggttcgc catgctccat ctatatcttc
    21721 gtttgatttt aagtagtaat ctattaaagt tgtgtatata ttcaaatata tctctagtga
    21781 gtgaatctcg ttggcttgta atgatagaaa agataattcc tcttcagtaa gaatttgctt
    21841 cttgcgaaat tcttttgcta tcgtgataat tcttctattt atactttctt cattgttccc
    21901 ccatagatct tctatttgta cccctagacg tggtgcgatg gattgtataa atgcttgaga
    21961 aggctttata tttccgtttt ctattcggct tagataggta atcgaggaga ttccatctac
    22021 tagttgtccc tgggtcattt ttttatgtat gcgaagttgt cgtatttttt caccaatctc
    22081 catgatgttg gtcctctcct atgttttata tatgaaaaca tatccaaaac tattatatca
    22141 atatacggac aaaatgtgta acttagtgat agattggaag ataaaaagtt ggtgaagaaa
    22201 tgtatttttg ttaatttaaa tcggtgaaag tggtatccac atggtatttt tttagtgcaa
    22261 ctttacaaat tgtattgaac taggtgaggg gtgtaatcta aagacaaaag aagggaggga
    22321 tttaccatga tggatatcga cccagcatta tcgtggatga gtgaggggct gaaacaaatt
    22381 agcttagctc aacaaaagcc actttttcag gtaaatatgc gtgaaaagag agggaaaaat
    22441 gtttcgtttc tcattgagaa agggcaggat acagataaag ttcaagatag ttcgtacctc
    22501 attcataaaa atacctttgc gcaaatgatc tacgaatcat tttacaatca ggggctaacg
    22561 tttaacaatt tgttacccat tttaattata ctcaatgaga gtcagattag cggcttttat
    22621 ttcccaggat tttatagata tgataagaat gaggaacgat ttgagttttt gagagagatg
    22681 gatagtgaag tggaagaaaa ggttcaatct tttttgcaaa ccaataacat ccagtctgcg
    22741 gtggcattgg gatatgcctt ggtgaatatt gatgaaatag taagctggga tgatgtggtt
    22801 gtggagatcc aaacagctgt gaaatcattc tctcaattaa ttcaactgca tggaggatta
    22861 aaggagactt gtttagtgcc cactttagcg agtggcctca agaagccaca accctctgac
    22921 tttttcctat caccgatttt gatcacccat tggattcaac cgcaataccc actaaattag
    22981 gggaggagat agatcctccg atccttggta gcatagccaa gtggtaaggc aaaggtctgc
    23041 aaaaccttga tccccggttc aaatccgggt gctacctcca aagataaaaa agtaccttct
    23101 ccgttaacgg ggaaggtact tttttgccta gcctggcgtg aacaaaatcg aggtctaatc
    23161 attctctgac aaagtgaaga gtttctctgc aagtaacatt attgggcaca ggatcattcg
    23221 ggagggggat ctgcttcaac gagatgtcaa aattgaaatc gtgcatgtcc ttttttggta
    23281 tagtcgtgga atccttccag ttgaagcaac tcttctttta cttttaaccc cccacgaaac
    23341 cctgtgagag cggtactttt gccgatgaca cgatgacagg gtatgacgat tgggatgggg
    23401 ttggccccat tggcagtccc tacagcacgt acagccttgg gattaccaac agtgttggcg
    23461 atatccgagt agcttcgggt ttcaccgtag ggaatctgtg ccaaggcgtt ccataccgag
    23521 gtctggaaag aggtaccgaa taaatcatag gggagagtaa aggattcccg gttgcctgca
    23581 aagtactctt ctaattgggc gatgacagca ttgagtggtt ttttgctttc gatcagggtg
    23641 gcatcaggga tttgcttttt tacccaagta cgtagggttt ctaaggattc tgtaggccaa
    23701 gtaatgcggc ataatccttg atcagttgaa gcgagataaa gggggcggtt ttgaaagatt
    23761 ggatggatga aggaatgcca gtatacagag gttctggtta gtctcatcgg ttagtttcct
    23821 ccatttcaag agatctaaag tttcactgct ggcattattt tggtagcgat tttagaagtt
    23881 aataaaacct gaatacttta tttatttcgt tttgatagtc atatttattc agatcattag
    23941 ctcaactata tatttattcc gtgcacgaaa acttagagta agtgaccatc aataaaataa
    24001 taatacaata aatagcgcac ctaatggtta gaaaaaagaa tagaaaccac cctccccatg
    24061 gtcttgaccc cgtcaagtag acaatagaaa aagaacctta tttaagcggc gatcttttct
    24121 cgttattcca cggaagaaag gtcgccaaat tttttctgaa accgtgcctc attgtaccag
    24181 aggaaggtac tttttttgtt tttggccctt catgtacata ctgaattcct cccttatatc
    24241 caattatata cgggggtggt tgaacttaag ggaggggaaa acacccctcc ctcattcgac
    24301 gcttactttc atcctaacct gaagggctag gttttctcct tcgcaatcta tcatttgttt
    24361 aactgatcta ccagtttgcc cgaacaaagt ttaagtattt tcatagaata gattagctct
    24421 ctactaatca ttgcaaggct ccaagaaaaa ttcatagtga atggtcaagc tgtaggtccc
    24481 ttgagaaatc cctgtagccg tacggatgtt tacaagttgg aaactctgca atccagaaga
    24541 agtaaaagaa cgcgagtttc cgggggagac cgaaggggtt ttttgatttt tcatgtgcat
    24601 aatccgaaag gttacaaagt cgctacttgt tctctcatct ttgatcacct gaccaaattc
    24661 gtacaatgtt ttatagcccc ttttcttttg tactttccgg tttgataaaa ttaaaggagg
    24721 aagtaatgat gtcttgttgt tcatcacgtg caacctgtcc ggatccgact tcatttcaag
    24781 aagcgatatg tggtaatttc tctactattc ttgccgcaga taataccgtt tggaaaagct
    24841 ataccagtag tggttcaagt cctggaccgt tttatgcgat gaccctgagt gtctatgctg
    24901 acacgacttc cctccctgtg gtggtggaag ttgtgactcc agctggaccc ataatattaa
    24961 cgcctcccgg taccgaagtt accgctggaa caacgaaaag tttcacccta ctgagtgtaa
    25021 atacagttaa tattcatgat attactgctg gtcaacttat tacagggaag tattctatca
    25081 ctctatatcg tagtatcttc tagtgcaggg ctatcaatca gccatatgca ccacttacta
    25141 gatcctttgt ggtgatggaa tctgcttgcc gaatcaggtt ataggttcct tgtcgaacct
    25201 gatggaaaca gatcaacggc cgatttgttt gcatgaaaaa ggcctcaaac ccttatgtat
    25261 taagggtttg aggccttttt tctgatcgcc aattaaagat ccttaacccc ttggcctcca
    25321 tcctgttaca tagcccagag agaataatca tatcagctct taccttggta ataccgacaa
    25381 aaatagtgcc atccaactcc gttaatggaa aaggtaattt ggttactatc ctatcatttt
    25441 gcccgaacaa agtttaaata ttttcataga ataaattatc tctctactaa tcattgcaag
    25501 gttccaagaa aaattcatag tgaatggtca agctgtaggt tccttgagac atccctgtaa
    25561 ccgcacggat gtttactagt tggaaactct gcaatccaga agaagtaaaa gaacgcgagt
    25621 ttccagggga gaccgaaagg gttttttgat ttttcatgtg cataatccga aaggtcaaaa
    25681 agtcgctact cgttctctca ttgtaaacac tgatcgttcc tgtcggaggg gtaatcaacg
    25741 aggattccca aaggatctca tgatcgcttt cattttctcc agaaatgtaa attttgccac
    25801 aaaattcatc tctgatcacc tggccaaatt cacaattcat ctctgatcac ctgaccaaat
    25861 tcgcacaatg ttttatagct ccttttcttt tgtactatcc ggtttgttaa aatttaagga
    25921 ggaattcaag atgtcttgtt gttcatcacg tgcaacctgt ccggatccga ctaggtttca
    25981 agaagaaata tgtggtaatt tctctacaga tcttggcaca gataataccg tttggaaaag
    26041 ctataccagt agcggttcaa cccctggacc gttttatgtg atgaccttga atgtctatgc
    26101 tgacacgact tcctttcctg tggtggtaga agttgtgact ccagctggac tcataatatt
    26161 aacgcctccc gctagcgaaa ttgccgctgg aacaacgaaa agtttcaccc tactgagtgt
    26221 aaatgcagtt aatattcatg ctattgctgg tggacaacgt attacaggga agtattctat
    26281 cactctatat cgtaatatct tctagtgcag ggctatcaat cagccatatg caccactcac
    26341 tagttcttac gtggtgatgg aatctgctcg ggtttgagaa taagggttaa aacctaaata
    26401 tggagaagac aatatgcttt ctcctgcttt gcggtgatca tgctcactcg gagttatgta
    26461 cc
//
