LOCUS       NZ_LT629789            26495 bp    DNA     circular CON 13-MAY-2024
DEFINITION  Amycolatopsis keratiniphila strain FH 1893 chromosome I.
ACCESSION   NZ_LT629789
VERSION     NZ_LT629789.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900105855.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 02:01:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,886
            CDSs (total)                      :: 8,813
            Genes (coding)                    :: 8,742
            CDSs (with protein)               :: 8,742
            Genes (RNA)                       :: 73
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 26 of 71
            Pseudo Genes (incomplete)         :: 51 of 71
            Pseudo Genes (internal stop)      :: 1 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:07:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7758333
            Orig. end                         :: 7784828
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT629789.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26495
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="29"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26495
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26495
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16495](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16495
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            245..1009
                     /locus_tag="BLU53_RS35550"
                     /old_locus_tag="SAMN04489733_7280"
     CDS             245..1009
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019816035.1"
                     /locus_tag="BLU53_RS35550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7280"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_228708109.1"
                     /transl_table=11
                     /translation="MGDERSSRQAANSEALGQVAHALSEVARSLTAEPDLHQTMKGIVT
                     AAVATIPGAEYAGVSLLEAGQLRTVAPSDDLVARLDELQHELGEGPCVDAIAEHHTYRT
                     GNLADDSRWPKFADTAASLGVASVLGFRLFATSTTLGALNLYSSQRDAFDADAEHIGEL
                     FAAHAAVALIGSQEQAQLRTALGTRDVIATAKGILMHRHHRTDAQAFTMLVEASQHANI
                     KLHDVAAWVVAEANNTAAGHDQRMEAARVTRG"
     misc_feature    complement(1389..1407)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.95"
                     /tool="antismash"
     misc_feature    complement(1615..1628)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     gene            1667..1966
                     /locus_tag="BLU53_RS45375"
     CDS             1667..1966
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013003.4"
                     /locus_tag="BLU53_RS45375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_197684729.1"
                     /transl_table=11
                     /translation="MTRYIDKDLYGAEFRECDLTGARLIGVVMQDAVTDGLITNLVVNG
                     VEVTEYVEAVLDRDHPVRVLIRSEDPADLREASRQLHAAWPPRSSERQVSSAAA"
     gene            1963..2226
                     /locus_tag="BLU53_RS45380"
     CDS             1963..2226
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS45380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_197684730.1"
                     /transl_table=11
                     /translation="MNDEWSAVQTMRHLVFAHDSWFRRCCLGSTELFTPMGIGTTVEPY
                     RGAHGLDLSLDPALDEIVSVRDGQAPSSRPGSTRSPLSRGTA"
     misc_feature    2258..2273
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.48"
                     /tool="antismash"
     misc_feature    complement(2568..2582)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            2762..2980
                     /locus_tag="BLU53_RS35560"
                     /old_locus_tag="SAMN04489733_7284"
     CDS             2762..2980
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04489733_7284"
                     /product="hypothetical protein"
                     /protein_id="WP_072029921.1"
                     /transl_table=11
                     /translation="MPLFSDIDGPAPEGAAEATVGQVVGELTRQARAGHVVYLTGPGDD
                     DVVAVAPVDVVKAGLAALGRTEDGTRL"
     gene            complement(2977..3633)
                     /locus_tag="BLU53_RS35565"
                     /old_locus_tag="SAMN04489733_7285"
     CDS             complement(2977..3633)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698394.1"
                     /locus_tag="BLU53_RS35565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7285"
                     /product="YdcF family protein"
                     /protein_id="WP_043828850.1"
                     /transl_table=11
                     /translation="MPTNQLPPDLQADVETLWAYHDMGHQPRRCDVGIGLGSHDLGVAI
                     HTADLYQQGLVDRIVFTGANAPTTIERFPRGEAVHYREHAVSLGVPTEAIMIETEATNT
                     SQNITHSRQVLTDAGIHPASIMLISRPYQQRRAYATCRKVWPEVEVICSSRPLPLDEYI
                     ASIGDIDRVINMLVGDTQRITEYARRGFAIQQDVPDEVNAAYQRLVDAGYTSRLI"
     gene            complement(3645..4871)
                     /locus_tag="BLU53_RS35570"
                     /old_locus_tag="SAMN04489733_7286"
     CDS             complement(3645..4871)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698395.1"
                     /locus_tag="BLU53_RS35570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7286"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_043828849.1"
                     /transl_table=11
                     /translation="MTDDLTIGERVAFYRQRRGLTQAVLAGLVGRSEDWLRKVEHDVLP
                     LDRLSVLRRLAHALDVALGDVIGEPVLMAGADESGRRTIPALRVALMDHRQFLAGPQPG
                     EPPRLDALAAELATQWGDYQNSRYARLIQRLPLLITETQTACQHYGHTSDDGVRAHTLA
                     ASAHQLATAFLTKLGEADLASISASRGLAAAHVSGSDLMIGSLYRSVAHALLSIGEFEQ
                     AVALSRAAADRLEPGLGTATPEYLSVYGMLHLVGAVASSRRDNRADTTAFLAEADQAAT
                     RVGHDANHLWTAFGPTNVTIHRMTTAMELGDVQVAVHLGPRVNTHGLPVERQARHAIET
                     ARAYVRWNRTDDALDVLLAAEQDAPEQVRYHRLSRILVREMIRLPRPATRAVELAYRMG
                     VHAADSHRP"
     gene            complement(5435..6778)
                     /locus_tag="BLU53_RS35575"
                     /old_locus_tag="SAMN04489733_7287"
     CDS             complement(5435..6778)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04489733_7287"
                     /product="hypothetical protein"
                     /protein_id="WP_081684720.1"
                     /transl_table=11
                     /translation="MTTDRDTGVRLLRQLRERRGWSWTDLARGLRDTARQLAVTSLMNR
                     QVASIQRTVARWESLTSRTSPGDRYQFLLAHLYARTPSGDLALGTGSDFAALLDALRHF
                     GAPPQRIRQLVELITQSAGGEGRDLLAVLSPTTHSSVAAVERDPSRLDPDLLSQLQDAV
                     AAINGQVGSTPFVRLQLQLAPIVESCGRLLQFDHVGPYDELMLLATDTYALAARLAFET
                     RDDEIAMALYADATEVAGRLKDRSHRAAVQTSHTMVALHATNNVDAALKIARAATADAH
                     RGTSYAIRARAHAVHAEICARSGQAREATEALDRAWKTVDQLTVDDPHGGFNVDRLNGF
                     DGLCALHIGDAGRAHQSLDRSLSALRLSGDLVQRGIVNADLALARLRLGDPFACVDLLH
                     EAVDITAATGGRVPAQRIRLARRDLRPWRAENFLAELDDHIHDTLIGR"
     gene            complement(6806..7294)
                     /locus_tag="BLU53_RS35580"
                     /old_locus_tag="SAMN04489733_7288"
     CDS             complement(6806..7294)
                     /GO_process="GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016701133.1"
                     /locus_tag="BLU53_RS35580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7288"
                     /product="DNA-processing protein DprA"
                     /protein_id="WP_051171775.1"
                     /transl_table=11
                     /translation="MTSAKERASVPRHVTITGTRSITAQAETQLTGLFDDYLRPFADPN
                     ATFYLGGAAGIDTSALDWLAEHTQAALTVVVPCTVADQPAVAGEAIHRWQRGGRLAGVV
                     ELRAEKLGSSAYHARNRWMVDRSGFVIGFPQGSDSTSGTWYTVNYAADQGKPRLVVPV"
     gene            7405..7995
                     /locus_tag="BLU53_RS35585"
                     /old_locus_tag="SAMN04489733_7289"
     CDS             7405..7995
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04489733_7289"
                     /product="hypothetical protein"
                     /protein_id="WP_112285791.1"
                     /transl_table=11
                     /translation="MTATMSLLSTMNRLTTKKKWSSAIDDMLRQVVDEGFAFYVCGERR
                     DPVVLVAAYYWKSYVDLLTITEPDRVTAARAVREPGFDVFGPRKVVWAYGNEAEPTLRA
                     LLNLTHPDHPDHPTCPHEPPRLMIVPAHLQRPMTFKAPDSWKVQNRVQRLESALASDLA
                     SMEAAGLLTREEGPLWSGQGGFVLPSGAPDGVV"
     gene            8376..9665
                     /gene="fxlM"
                     /locus_tag="BLU53_RS35590"
                     /old_locus_tag="SAMN04489733_7290"
     CDS             8376..9665
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="BLU53_RS35590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7290"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_043828846.1"
                     /sec_met_domain="PCMT (E-value: 1.3e-40, bitscore: 138.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKPVEGNNEADSSERVAHLRTKMVDDLIAEGTIVSAQVEAAMRK
                     VPRERFAPGVDLEEVYQLYNGVVTKRDESGNSVSSVSAPQVQAHMLQQAEITEGMRVLE
                     IGSGGYNAALIAELVGPAGRVTTVDIDQDITDRASRFLGETGYSQVNVVFSDAEAGVTE
                     QAPYDRILVTVNTWDVPPAWVEQLAPTGLLVVPLQVRGLSRTIAFEKADECLVSRSARL
                     FGFVSMRGAGAHQSKLLVMRGGEVTLRLDDDFPVDPTELEGVLDTPRVEVWSGASIGRF
                     EPWAGTQMWLATALSGFCRVILDKKLDSGLISPPGSHSAAMAVVDGGNLAYVTTRSSTV
                     NESAVEFGVHAFGPDAERLAEDVAEQLRIWERDHRNGPGPQFRVYPAGTADDLMPAGRV
                     VDKKHSRITISWPHAANAAAGRSALQENTK"
     gene            9680..9880
                     /locus_tag="BLU53_RS35595"
                     /old_locus_tag="SAMN04489733_7291"
     CDS             9680..9880
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="BLU53_RS35595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7291"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_043828845.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 9.1e-15, bitscore:
                     53.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVLFSGGATALAERPVADDDEFALDVRVVVAYAPVMGDCPTDD
                     GCGNTCAGNDSACNSFADDPS"
     gene            10001..13039
                     /locus_tag="BLU53_RS35600"
                     /old_locus_tag="SAMN04489733_7292"
     CDS             10001..13039
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="BLU53_RS35600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7292"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_197684732.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.9e-204,
                     bitscore: 679.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.3e-17,
                     bitscore: 61.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.1e-14, bitscore:
                     50.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRASTDPSGLDLPSALDLYGDGGIERGIAWLTMQWQRADVRTAV
                     GYASPALSRQIDEMVAAGSRDLRAVRRVVISLASYLLRWQQRPTPFGLFAGVGLARIGA
                     AAKVRWGFEHRVAVRADAAWLGDVITRLHQCVPLLERISVVVNNAGSVRGDRFVAPGSP
                     PDGAGQELAPIEVSIGLGRPVRAAVEAAQKPVRFGALREQIMARFPAATRQSVDTMLTG
                     LLDEGILISSLSAPMTCQDPLDHVCTKLEAVEAKTIPEVTHTVRELTTIREQLAGEAVA
                     VTETEVTRRMQALSAVADMPLLADTILDCDVEIPEQVAQEARDAVRVLYRLSPYPLGYP
                     AWRDYHSRFRARYGIGALVQVLELVADSGLGLPAGFLGSSRGRTAHQMSERDEKLLAMI
                     QRATVDGTGEIVLTDQAIEDLTASDPADLHLPARVEVAVEIHSNGVEALSRGRFTLAVT
                     GTPRPGSSMAGRHAHLLPDDGRDAVAASFTAAEPGTVAAQLSFTPRKRRNENVARTEQL
                     LPHVIPVAEHHERDEHLINLTDLAVTADDRRFYLVQISTGQRVEPRVTHALEAGVHTPP
                     LARFLAEITTARASVYKAFHFGAAARLPYLPRVRYRRTILSPARWLLAAGDLPGRRASF
                     AVWEAGLDAWRQQSRVPACVALVELDRRQPVDLNHPLHRLLLRTRLDRGGRLELRETSG
                     PADIAWLGRAHELLIPLVLDSAAAASRSSSIAVPQQVVASDASHLPGDSPILCAQIYGH
                     PDRFDEVLTERLPSLLGAFGDVALNWWFRRHRQMSRPDDDQYLVLYLRLPQSSAYGSAA
                     ERLVEWASTLRSERLLSHVALTTHEPQTGRYGHGSALERAYDLFAADSAAALAQIALTI
                     RTGTHRQAVAAASFVDVAVNFAGSVQSGLDWLLRELRQQHGRLQPALRDRALELTDPEA
                     VWTSLRSVSGGEKVVTAWQRRAVALAAYRVALAEQRDPLTVLPSLLHLHHIRAVGVDPA
                     LERVTGRLARASARRAAARRGEI"
     aSDomain        10430..10708
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BLU53_RS35600_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.40E-19"
                     /identifier="RREFam001.1"
                     /label="BLU53_RS35600"
                     /locus_tag="BLU53_RS35600"
                     /protein_end="236"
                     /protein_start="143"
                     /score="61.6"
                     /tool="antismash"
                     /translation="VVVNNAGSVRGDRFVAPGSPPDGAGQELAPIEVSIGLGRPVRAAV
                     EAAQKPVRFGALREQIMARFPAATRQSVDTMLTGLLDEGILISSLSAP"
     gene            13041..14273
                     /locus_tag="BLU53_RS35605"
                     /old_locus_tag="SAMN04489733_7293"
     CDS             13041..14273
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155774.1"
                     /locus_tag="BLU53_RS35605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7293"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_081685171.1"
                     /sec_met_domain="LANC_like (E-value: 6.1e-42, bitscore:
                     142.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTAIALADLAQRHANNLALPGPCPEDKPWADQSLSKGTAGMAL
                     LHIERALIGRGTWREAHLWVTKAVAGRVSATDTSGLYLGAPAVAFMLDAAATGASGRYQ
                     EALADVDGHVVALSHRRAEAALARIKAGEFPGFREYDVFFGLSGLGALLLRRASDSSAM
                     ERVLDYLVALARPRQVDGDVLPGWWVGHDPHRRISASYQEGHGNFGLAHGITGPLALLS
                     QAMRRGIIVDGQHEAIITICEWLDSWQQEGAAGPWWPEWITLAELRTGQPHQSGPARPS
                     WCYGTPGIARAGQLAGIATGDAHRQRMYEQALIRCLDDPEQLARITDGGLCHGWAGLYQ
                     TVWRSAQDAGTSAFDEYLPPLAAHLGQHTRHGPVAKRGFLEGTAGTALALHTAVYNTTP
                     TSGWDACLLID"
     gene            14255..16495
                     /locus_tag="BLU53_RS35610"
                     /old_locus_tag="SAMN04489733_7294"
     CDS             14255..16495
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="BLU53_RS35610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7294"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_081685170.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.4e-38, bitscore:
                     132.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHRLTPREVELRSSDADESAVAQGAEYGVLLVLAGASLNEAAA
                     AIHVEPADLAEAVEVYRKAGRHALERQAASDWWQIYIEFIDWSTAEQSAADTIAPLLHR
                     AGEDGLVTKWWFMRKHPCWRLRIHPGRDGHAMRDHLGAALDELAADDRIAQWWPGTYEA
                     EMQAFGNWTGMEAAHDLFYEDSRAVMHLAHNGGGGLGRRELSLLLCNTLMRAAGLEWYE
                     QGDVWHRIAQERPLPEDVSAANLTAMASDLKQLLLANTAPGGPLLRAEGPLASSADWAS
                     AFRQAGRTLGSAARTGTLQRGLREVLSYLIIFHWNRLGLPARTQSILAWATRTVILGLP
                     GHVPPNPTLSGGPTSGTTAPPLAARANEGVAERALARFPLVSQRRFPCPDLETQVRNVR
                     ECANSCQESTTVEERMNRACTVWNLSARIAAECGMPDVAISLCRRQFRIFRAASPLSAG
                     SAIASLQPVVNLARLTRRAGDNQGAYRELEAINHAVRNGGAAVIHGDLVDFDGLIADRS
                     SEVDNWLRQVMREDGTRALVAAGQWTNAAAHAEKYDETRNQFREARQTRAIALALNGKA
                     NLALKLIDNTAKSDAWEYAGAACLRSYLLLQERSIGAGDVIGMLNDVRHVCGASHRPTG
                     LFRIRLGLTAADLAVAAQGDAGLLCAELIEKAERSADAFMAREVLAHPECQTLATPKQS
                     ETLGLLVERAGFDSGQVPAVVMDDLMSSVHTAETVLIANLGVTASRLGPIRD"
     misc_feature    16160..16162
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16962..16979)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.93"
                     /tool="antismash"
     gene            17115..17447
                     /locus_tag="BLU53_RS44800"
     CDS             17115..17447
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.4"
                     /locus_tag="BLU53_RS44800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_235147155.1"
                     /sec_met_domain="APH (E-value: 1.7e-05, bitscore: 23.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSRGDSNLFNWLWGEPNVHVVDWEFIGHSDTVYDAAELVEHLSA
                     RVIDDEWRVALLPDHGIVDDTARRRFLAAQRTVALSLLWKRGDKRADDVEFQVKWVREL
                     MNSSFL"
     gene            17933..18757
                     /locus_tag="BLU53_RS35620"
                     /old_locus_tag="SAMN04489733_7296"
     CDS             17933..18757
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04489733_7296"
                     /product="hypothetical protein"
                     /protein_id="WP_043839739.1"
                     /transl_table=11
                     /translation="MGELGVIRNYAYWSDRRIRDIASDNGIPLERRVSWKAKTAFPLIG
                     GLEVAPEARTLDRAEVAPRIETAIGDLAVQDFVTPPPVMFAKGVGRVEFAQFTGGIEKR
                     QVVVIYTNTRSSTGSRVDVCLFGSLENTADYIGGSDQPPPGWSSSAARTIALYIQSRGT
                     INNSQWDDPESLAVEALKIATEQGVTGNWDEHENKPWTRGFTLGHTTESEWFAQIYSDV
                     VLDKDRWTFPSDGGISPDVERILIGAPLWVRTPGAHAVTRYRDLRSGSDRAT"
     gene            18818..19588
                     /locus_tag="BLU53_RS35625"
     CDS             18818..19588
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_043839741.1"
                     /transl_table=11
                     /translation="MSDDWEQRWASGARTFYIAEIVRQASYALAAVQQALQLSRDPQGR
                     SEAWPAVQSFLTATAIISKLLWPVRAERADRKSRWRRFRADRLRTELMVSDTSALRDRK
                     VRDSADHFDERIDDLVRDQRIPQAWTDLADEELTQRAAPFRAIDADTGEVLAGHDRMAL
                     APVVTELNAILQRCETIEPGSSSAPDVTMLLATLRWPPLPSLFAPTERSDEPVTARASI
                     AATGPQTLEGLITLVIDQLFEHPDTNRTRRRKHR"
     gene            complement(19853..20851)
                     /locus_tag="BLU53_RS44805"
                     /old_locus_tag="SAMN04489733_7298"
     CDS             complement(19853..20851)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025539.4"
                     /locus_tag="BLU53_RS44805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7298"
                     /product="YaaC family protein"
                     /protein_id="WP_228708110.1"
                     /transl_table=11
                     /translation="MSAAGRKLRSLRALRHDPPGYAKQGARRTTFQSALEQCEQFLDAA
                     SDTGYATRPVQLFYALSQAGRAIVAASPRIGNQVSKVSGHGLTANTNTATAAEVLVTAT
                     KSGLFPAVASAIDVEALVPNEPVALRELWPLLPETVDVPLTDDVMVPVLLFFQDGWPEI
                     GTFAHAEVNWLPRRVHDLFGQDPVRVKEHLDRYPALRDSVLHVSQPMGGLGWRNAGPGM
                     GLSVEWRSGSPPLMLADNKTFSDLGVACYRSADDSLVTPAIGSMATGLHPFLALWAVLL
                     ALSSLARYQPATWSKMIDVDRSPEANAIEHLLEEATTSVPATALHLLTTFR"
     misc_feature    complement(20030..20032)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21277..21465)
                     /locus_tag="BLU53_RS35635"
     CDS             complement(21277..21465)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_072029935.1"
                     /transl_table=11
                     /translation="MDEQTRPCARLYPYSTRDVAENVVHLLIDVADVFAAIVEQVVPWW
                     QAVIVLHEQLRMWTSAS"
     gene            21615..22022
                     /locus_tag="BLU53_RS35640"
                     /old_locus_tag="SAMN04489733_7299"
     CDS             21615..22022
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04489733_7299"
                     /product="hypothetical protein"
                     /protein_id="WP_043829893.1"
                     /transl_table=11
                     /translation="MGSQSTHGFNRLSNKASSWLAHPLFFGFVVLALVAWVPTLWLMET
                     GASDLVVDSITNPLQLLLLVLLHNNQHRVSKASDDRADQTARALATLLEHAATTTQDEQ
                     RSQQLREEAVQLQRDAEKDNELSSGDTQRRE"
     gene            complement(22231..22641)
                     /locus_tag="BLU53_RS35645"
                     /old_locus_tag="SAMN04489733_7300"
     CDS             complement(22231..22641)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS35645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN04489733_7300"
                     /product="hypothetical protein"
                     /protein_id="WP_144024174.1"
                     /transl_table=11
                     /translation="MQLERINTATKTELAGARKMFPRSRNVKLAPTVTSRGRCCTIELT
                     LAVNDPGNENALVLNAGVYGDNYLLVLLNQKAKNFKEGGIVTATGTVENISATSSSAKN
                     TGLVQAAIYDAYTHEQFLHNANVRAADDTVPR"
     misc_feature    complement(22510..22512)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(22798..23214)
                     /locus_tag="BLU53_RS35650"
                     /old_locus_tag="SAMN04489733_7301"
     CDS             complement(22798..23214)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019819361.1"
                     /locus_tag="BLU53_RS35650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7301"
                     /product="YetF domain-containing protein"
                     /protein_id="WP_197684733.1"
                     /transl_table=11
                     /translation="MQPQRGWVPAAGEGDLEPAAGSRGEDAEQHGALAILTLVVLDRVA
                     DMLKSRSTAFSRLAEGAPLVLVEHGKPLQERLRKEHISTDDILASARKSQGLLRLDQIE
                     YAVLESSGGISIIPKKSQQEREKDLEESRRIGGE"
     gene            23125..23588
                     /locus_tag="BLU53_RS44120"
                     /old_locus_tag="SAMN04489733_7302"
                     /pseudo=""
     CDS             23125..23588
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018884.4"
                     /locus_tag="BLU53_RS44120"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7302"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLFGILTPAPGGGFEVTLAGGGHPPALRLHDGEVEEIRPKGGMLV
                     GALPDAGSPPATCTWSPGRPCCSTPTDSPKPAPTAPSSARTDSPRSSPPAPAPSPSS"
     gene            complement(23860..24099)
                     /locus_tag="BLU53_RS46085"
                     /old_locus_tag="SAMN04489733_7303"
     CDS             complement(23860..24099)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="BLU53_RS46085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7303"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_043829889.1"
                     /transl_table=11
                     /translation="MNIQDAHKRHLDTNFAVWHKSPLSNPPDNQCVEVSFSSNAVGLRD
                     SQNPEGYVLVFDQGEWEAFIGGVEAGKFRLPKSQ"
     misc_feature    24059..24079
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.25"
                     /tool="antismash"
     gene            complement(24140..25003)
                     /locus_tag="BLU53_RS35660"
                     /old_locus_tag="SAMN04489733_7304"
     CDS             complement(24140..25003)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015802421.1"
                     /locus_tag="BLU53_RS35660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_7304"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_228708111.1"
                     /transl_table=11
                     /translation="MKESVTQHLQLPPAVMKVVLGNQLARLRELAEVTQEDAAAVLGCT
                     QQKIAHIEGGSGIKLIELNALLDRYAANEADRAYTRDLQSESNRRTKRGAFSTRFRQYL
                     RLLVDMEPSCNRYFSYQALVIPGLLQTEDYMRRNARAWRPSLTADEIDKYAANRLARQR
                     VLENADQQFWFIIDEAALRRTEGGPVMKAQIKRLVETIDRPNVELQVVPFGVGYYMGQG
                     HDYTIFGYDTKPAVDIIYLEQHDGGEYVDNSKRTARYLTLWDHQKAAASGPEQTRRALL
                     GIASSL"
     gene            complement(25717..25887)
                     /locus_tag="BLU53_RS44810"
     CDS             complement(25717..25887)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLU53_RS44810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157376276.1"
                     /transl_table=11
                     /translation="MRSNRCSEPEQISGDDFVKVVAGAGDEGPTLDVGPFDDRACQHPD
                     PQAGEHTPTKV"
ORIGIN
        1 gtcctgcacg aacgagggct gccaatcaat gacaacgcca ccgtcccgga cctggtcaag
       61 gcttcccagc aagctctgca cctgcacccc tcgccgacgt catccacaac gccatcgggg
      121 agacgagccg acatcggcga ggtaccgcgc gacggccgac cagtgcgatg cattcgggtc
      181 tgccgccacc gctgtcgaat accgcatctg gccgtgacgt ctatatccgg acagaatggg
      241 gcaggtgggc gatgaacgat catcccggca ggctgccaac agtgaggcgc tggggcaggt
      301 agcgcacgct ctcagcgagg tggcccggtc actgaccgcg gaaccggatc tgcaccagac
      361 catgaaaggg atcgtgactg ccgcggtggc aacgatccct ggcgcggagt acgccggggt
      421 gtcgctgctg gaggccgggc agctgcgcac cgtcgcgccg tctgacgatc tcgtggcccg
      481 cttggacgag ctgcagcatg agctgggcga aggcccatgc gtggacgcca tcgccgagca
      541 ccacacctac cgcaccggca acctcgccga cgactcccgc tggcccaagt tcgccgacac
      601 cgcggccagc ctcggtgtgg cgtccgtgct ggggttccga ttgttcgcca ccagcaccac
      661 cctgggcgcg ctgaacctgt actcctcaca gcgcgacgcg ttcgatgccg atgccgagca
      721 catcggtgaa ctgttcgccg ctcacgccgc cgtcgccctg atcggctccc aggaacaggc
      781 ccagctacgc accgcgctcg ggacccgcga cgtgatcgcc acggccaagg gcatcctcat
      841 gcaccgccac caccgcacgg acgcgcaagc gttcacgatg ctggtcgagg cgtcccagca
      901 cgccaacata aagctgcacg acgtcgctgc ctgggtcgtc gccgaagcca acaacaccgc
      961 cgcaggccac gaccaaagaa tggaggccgc tcgggtcaca cggggctgaa acccggaggc
     1021 cttaacatcc caacacccgg tatttcacag ggcgccaggt ccgggctacc ccccaatggg
     1081 tgcgccgacc tcgctagagg ggatcgtggc cctatcacac cagtggaggc atagctggcg
     1141 accccgtgtt gctacgaggt ggcgagttcg tggcggctgt gctcgcgcag cagaccacag
     1201 gcctgccgtg gttcgtcggc gaagcccaca ccgtcgtcct ccaggcacaa gaggtcttca
     1261 ccgaggtggt ggacctcccc cgagggtgag ctcgttgtcc cgctcgccct cgcgttcgac
     1321 ccaccggcgc atctggcccc tgtcctgcca gtcaccgcgg cggtagacca cctcgacatc
     1381 agactcgtcg tagaccttgt acaacttctt ctccgtcatg cccccgggtg atttcagggg
     1441 tgagtttccg ccccagttcg gaacgagttt tggccgcact tcgcactccg gccagttgat
     1501 tcggtgaacg agttttggcc ccacttgttg atcttgtccg ttggtctggt cgacgggggc
     1561 tgggcgcggg tgtgcgcgag ccggaaagcg ggcgacgacc ggcaggagcg agacgcaacg
     1621 gcgatgccag ccagaaatgt cggtgctcgg acctagtatg cagagcatga cgcggtacat
     1681 cgacaaggat ctgtacggtg cggagttccg cgagtgcgac ctgaccgggg cacgcctgat
     1741 cggcgtcgtc atgcaggatg ccgtgaccga cgggctcatc accaacctcg tggtgaacgg
     1801 cgtcgaagtc accgagtacg tcgaggcagt gcttgaccgg gatcatccgg tgcgagtgct
     1861 gatccgctcc gaggaccccg ccgatctgcg cgaggcatca cgtcagctcc atgccgcctg
     1921 gccgccacga tcgagcgaac gccaggtatc gagcgccgca gcgtgaacga cgagtggtcg
     1981 gcggtgcaga cgatgcgcca cctggtcttc gcccacgact cgtggttccg ccgctgctgc
     2041 ctgggctcga cggagctgtt cactccgatg ggcatcggga cgaccgtcga gccctaccgt
     2101 ggagcgcatg ggcttgacct ctccctcgat ccggccctcg acgagatcgt gagcgtgcgt
     2161 gacggacagg ccccgagctc gaggcctggc tcgacgagat caccgctgtc gcgagggacg
     2221 gcataatgat acgcaaaaac gcattaatca ttgttgcaac gttaatcact gtcgcggctg
     2281 cctactttgc ttacgaagcg gtgacacacc acagttacat atacggatta atatccttct
     2341 ttgctgtcgc cttagcggct accgctgtga ggagctatct aaagaaccag cgacaataga
     2401 taaaaggtaa acccgtcttt gtcaccgtta acggaatatg ggcgaacgcc aagacaagga
     2461 cgggttccct tgcccccata cggcggcaag gggacccgtc cttcgtcgta acgttcctga
     2521 tgttgacgaa accggggcga gccacaggcc cccgcaccgc gtcctcgatc ggcgagcttg
     2581 atgtagcggc ggctgactcg gcgctagcgc ctccggccca gcacagcccg cacggcgggt
     2641 cacctgaacc atcaatctga gcgattcacg cggggcttct accgtctgct cgcacgtggg
     2701 aacaacgctc ggagcggctc gttgtatgag gaagcccgcg cggaggtact acgctggcag
     2761 gatgccgctg ttctctgaca ttgatggtcc ggctcctgag ggggctgccg aagcgacggt
     2821 cgggcaggtc gtgggtgagc tgaccaggca ggcccgtgcc gggcatgttg tgtacctgac
     2881 cgggccgggt gatgatgacg tggtggctgt cgccccggtc gacgtggtga aggcggggct
     2941 cgccgcgttg ggccgcaccg aggatggcac ccgcctctag atcagtctgc tggtgtaacc
     3001 ggcgtcgacg agtcgctggt aggcggcgtt cacctcatcg ggtacgtcct gctggatggc
     3061 gaaaccccgg cgggcgtact cagtgatgcg ttgggtgtca ccgaccagca tgttgatgac
     3121 ccggtcgatg tcgccgatgc tggcgatgta ctcgtcgagt ggcagtggcc gtgatgagca
     3181 gatcacctcg acctcgggcc acactttgcg gcaggtcgcg tacgcgcggc gctgctggta
     3241 gggccgggag atgagcatga tcgaggcggg gtgtatgccc gcgtcggtga ggacctggcg
     3301 gctgtgggtg atgttctggc tggtgttggt cgcctcggtc tcgatcatga tcgcctcggt
     3361 ggggacgccg aggctgacgg cgtgttcgcg gtagtggacg gcttcgccgc gggggaaacg
     3421 ctcgatcgtg gtcggcgcgt tggcgccggt gaacacgatg cggtcgacca ggccctgctg
     3481 gtacagatcg gcggtgtgga tcgcgacgcc gaggtcgtgg gagccgagcc cgatgccgac
     3541 gtcgcagcgg cgcggttggt ggcccatgtc gtgataggcc cacagggtct cgacgtcagc
     3601 ttgaaggtcg ggcggaagct ggttggtcgg catgtcggtg gaccttacgg gcggtgtgag
     3661 tcggcggcgt gcacgcccat tcggtaggcg agttcgaccg cgcgggtggc tggtcggggc
     3721 agtctgatca tctctcgcac gaggatgcgc gacagtcggt ggtagcgaac ctgttcgggc
     3781 gcgtcctgtt cggccgctag cagcacgtcg agcgcgtcgt cggtgcggtt ccatcggacg
     3841 taggcgcggg cggtttcgat ggcgtgccgg gcttggcgct ccaccggcag cccgtgggtg
     3901 ttcacgcggg ggccgagatg gacggccacc tggacgtcgc cgagttccat cgccgtggtc
     3961 atccggtgga tcgtgacgtt ggtgggcccg aacgccgtcc acaggtggtt cgcgtcgtgc
     4021 cccacccgcg tggccgcttg gtcggcctcg gcgaggaagg ccgtggtgtc cgcccggttg
     4081 tcgcgccggg aggaagccac cgccccaacc aggtgcagca tcccgtacac cgacaggtac
     4141 tccggtgtgg cggtgccgag gccgggttcg agccggtcgg cggcggcgcg gctgagcgcg
     4201 accgcttgct cgaactcgcc gatggacagc agggcatgcg ccaccgaccg gtacagcgac
     4261 ccgatcatca ggtcactgcc actgacgtgc gctgcggcca gcccgcggct ggccgagatc
     4321 gacgcgagat cagcctcgcc gagtttcgtc aggaacgccg tagccagttg gtgggcgctg
     4381 gcggccaacg tgtgggcgcg caccccgtcg tcgctggtgt gtccgtagtg ctggcacgcg
     4441 gtctgggtct cggtgatcaa caggggtagc cgctggatga gccgggcgta gcgggagttc
     4501 tggtagtcgc cccactgcgt cgcgagctcc gcggcaaggg cgtccaggcg aggtggctca
     4561 ccgggctgcg ggccagcgag gaactggcga tggtccatca gcgccacgcg cagcgccggt
     4621 atcgtccgtc ggcccgattc gtcggccccc gccatcagca ccggctcgcc gatcacatcg
     4681 ccgagcgcga cgtccaaggc atgcgcgaga cgccgcaaca ccgacagccg atccagcggg
     4741 agcacgtcgt gctccacctt gcgcagccag tcctcgctgc ggccgaccag ccctgccaga
     4801 accgcctggg tgagcccgcg ccgctgccga tagaacgcca cgcgttcccc gatcgtcagg
     4861 tcatcggtca tgcctcgcat ggagtacatc ctcccacccc cgtcgcccac gaccccagag
     4921 aaatcctccc ggtcccaccc cgccaacaca cctagcgtcc tcgtccagcg acaacacgcg
     4981 acacagggcc gcgaacgtcg atcgttccgc caacgagcga accgggagtg atagtgaccg
     5041 cgatcaggga cacgcagaca cagcgcaacc atccctgccg gcgttcaatt gctcgttcgg
     5101 cagccaatca agctcctgcc gtgctggccg tgccccgacc ggccagcacg gcaggtccga
     5161 ctattgggct cgccggtgtt ctcccgcggg ccagggtgac cttcccagtt ggcggccacc
     5221 agtgccaccg gtactggatc gtctgcgggt actacgagtg cgttcacggt catgtggtgc
     5281 cgatccatgg ccgggagcgg acgacacgat gaccaacgag atcatctcca cgcccgaacg
     5341 gcatgctgcg ctgccactcg tgagccggga ctggatctgc gcagtgaagt ccgtgctccg
     5401 agaccgcgcc gaccaggaac ccaacccttc cggttcatcg cccgatcagt gtgtcgtgaa
     5461 tgtggtcatc gagttcggcc aggaagttct cggctcgcca tggacgcaga tctcgtcgtg
     5521 ccagacggat ccgctgtgcg ggcacccggc cgcccgtcgc cgctgtgatg tccacggctt
     5581 cgtgcaagag atcgacacag gcgaagggat caccgagacg cagtcgcgcg agggccaggt
     5641 cggcgttcac gatgcctcgt tgcaccaagt cccccgacaa cctcaacgcg ctgagcgagc
     5701 ggtcgaggct ttggtgggca cggcccgcgt cgcctatgtg gagagcgcag agtccgtcga
     5761 agccgttcag gcggtcgacg ttgaatccgc cgtgagggtc gtcgacggtc agctgatcga
     5821 cggtcttcca cgctcggtcg agtgcctcgg tcgcttccct ggcctggccg ctccgagcac
     5881 agatctcggc gtgaacggcg tgtgcgcggg ctcgaatggc gtaactggtg ccccggtgcg
     5941 catcggcggt cgcggcacgg gcaatcttca gcgccgcgtc cacgttattg gttgcatgca
     6001 aggccaccat cgtgtgactc gtctgtaccg ccgcccggtg gctacggtcc ttgagccgtc
     6061 ccgcgacctc agtggcgtcc gcgtacaggg ccatggcgat ctcgtcgtcg cgggtctcga
     6121 aggccagtcg cgcggcaaga gcataggtgt cggtagccag cagcatcagt tcgtcgtacg
     6181 gaccaacgtg gtcgaactgc aggagccgac cgcaggactc gacgatcggc gcaagctgga
     6241 gctgaagacg gacgaacggg gtcgatccga cctgtccatt gatggccgca acagcatcct
     6301 gcagttggct gagcaggtca ggatcgagcc gagatggatc gcgctcaaca gcggcgacgc
     6361 tcgaatgggt ggtaggcgag agcacggcca acaggtctcg gccctcacct cccgcgctct
     6421 gagtgatcag ctcaacgagc tgtcggatgc gttggggtgg cgctccgaaa tggcggagtg
     6481 cgtcgagcag cgcagcgaaa tccgatccgg tacccagcgc caggtctccg gatggggttc
     6541 gcgcatagag gtgggccagg agaaactggt agcgatcgcc gggactggtt cggctagtga
     6601 gactctccca cctggcgacg gtgcgctgga tgctcgcgac ctgcctgttc atcagcgagg
     6661 tgacggcgag ttggcgcgca gtatcgcgca agcctcgggc gagatcggtc caggaccagc
     6721 cgcgtctctc gcgcagctgc cgcagcaggc gcaccccggt atcccgatca gtggtcacgc
     6781 cgcccagtac accatctctc gaaagtcaga ctggcacgac cagccggggt ttaccctggt
     6841 cggcggcgta gttcacggtg taccaagtgc cgctcgtcga atccgagccc tgcggaaaac
     6901 cgattacgaa gccgctgcgg tcgaccatcc agcggttgcg ggcatgatag gccgaggagc
     6961 cgagcttttc agcgcgcagc tcgacgacgc ctgcaagccg gccgcctcgt tgccatcgat
     7021 ggatggcctc gcccgcgaca gctggttggt cggccacagt gcacggtacg acgacggtca
     7081 gggcggcctg tgtgtgttcg gccaaccagt ccaatgcgga ggtgtcgatt ccggcggcac
     7141 ctccgaggta gaaggtggcg ttcgggtcgg caaacggccg gaggtagtcg tcgaacaggc
     7201 cggtcaactg cgtctcggcc tgggcagtga tcgagcgtgt gccggtgatc gtgacgtgtc
     7261 gaggcacgct cgcgcgctcc ttcgcggatg tcatcgaatg tcatctgccc ccgtcgtacc
     7321 tagtcacgat ctcatgaacg caccggctgc gacgaggctc ccccgaccgc gtcgcagccg
     7381 gttgcctgcc caacgacgac cacggtgacc gcgaccatga gcctgctatc cacgatgaac
     7441 cgcctgacga cgaagaaaaa gtggtcgagt gcgattgacg acatgctccg acaggttgtc
     7501 gacgaaggat tcgctttcta cgtctgcggc gagcgacgcg atccggtggt cttggttgcg
     7561 gcctactact ggaagagcta cgtcgacctg ctcaccatca ccgagccgga ccgagtgacc
     7621 gcggcgcggg ccgtgcgcga accgggcttc gacgtcttcg gtccccgcaa ggtggtgtgg
     7681 gcctacggca acgaggctga acccaccctt cgagcactgt tgaaccttac acatcctgac
     7741 cacccggatc atccgacctg cccacacgag ccgccacgcc tcatgatcgt gcccgctcac
     7801 ctacagcgac cgatgacatt caaggcaccc gattcgtgga aggtccagaa ccgcgtacag
     7861 cgcttggaaa gcgcgctcgc gagtgacctc gccagcatgg aagcggctgg cctgctgacg
     7921 cgcgaggaag gccctctctg gtctgggcaa ggaggcttcg tcctcccaag tggcgctcca
     7981 gacggggtgg tgtgacacgt gggcgggata cgcgaagtgg ttgccgtgat cgtcgcagcc
     8041 gacagtcggc tcggcggcgc cgtccgagcg atcgacgacc tggccggaca cttaccgcca
     8101 ccggaagagc agcgcacgtg cccgctctgc tcggtccagt cctggccctg cgctcggttc
     8161 gacgacgcag ctcaccgcgt gcaggctgct gggctacgac tcgacgactt tgtaccgcca
     8221 gacctgcacg aacgtctccg gcatttgacc cgccaaccac tgcccagacc atcagctcgg
     8281 ggtccgggcg actggttcga ccaggggcga cacgatcgat gacgccttct ccacccaccc
     8341 gcagtgccac acgacaagga agtcagttga acgacatggt caagcccgta gagggaaaca
     8401 acgaggccga cagttccgag cgcgtcgccc acctgcgcac aaagatggtc gatgacctga
     8461 tcgccgaggg cacgatcgtg tccgcgcaag tcgaggccgc gatgcgcaag gttccacgcg
     8521 aacggttcgc gcctggtgtg gacctggagg aggtctacca gctgtacaac ggcgtggtta
     8581 ccaagcgcga cgagtccggg aactcagtca gctcggtgtc cgcgccgcag gtgcaagcac
     8641 acatgctgca acaggcggag ataaccgaag gcatgcgggt cctggagatt gggtccggcg
     8701 ggtacaacgc cgcactgatc gccgagctcg tcggtcccgc ggggcgcgtc accacggtcg
     8761 atattgacca ggacatcacc gatcgagcca gccgcttcct cggggagacg gggtattcgc
     8821 aggtgaacgt cgtattctcc gatgccgagg ctggcgtcac tgaacaggcc ccgtacgacc
     8881 ggatcctggt caccgtcaac acgtgggacg tgccgccggc ctgggtggaa cagctcgcac
     8941 cgaccggact actcgtggtt cccttgcagg tcagggggct gtcgcggacg atcgcgttcg
     9001 agaaagcaga cgagtgcctg gtcagccgat ctgcgcgcct gttcggtttc gtgtcgatgc
     9061 gcggtgccgg ggcgcaccag agcaagctgc tggtcatgcg cgggggcgag gtcaccctgc
     9121 gcctcgacga tgacttcccc gttgatccca ccgagctgga gggcgttctg gacacgccgc
     9181 gggtggaggt ctggagcggt gccagcatcg gccggttcga gccgtgggcc ggcacccaga
     9241 tgtggctcgc tacggcgctg tccggtttct gtcgcgtgat cttggacaag aagctggaca
     9301 gcggcctgat ttccccgccc ggaagccact cagccgcgat ggctgttgtc gacggcggca
     9361 atcttgccta cgtcacgacg cgcagcagca cggtcaatga gtctgccgtc gagttcggcg
     9421 tccacgcctt cggacccgac gcggaacggc tcgccgagga cgtggctgag cagctccgca
     9481 tctgggagcg ggatcaccgc aatggacccg gcccccagtt ccgcgtctac ccggcgggca
     9541 ccgctgacga cctgatgcct gcagggcgtg tcgtcgacaa gaagcacagc cggatcacga
     9601 tctcctggcc acatgcggct aacgctgcgg ccggtcggag tgccctgcaa gaaaacacca
     9661 agtaaggaga gtgacccaca tgtccgaggt cctgttttcg ggtggcgcca ccgcgttggc
     9721 agaacggccc gttgcggatg atgacgagtt cgcgctggat gtacgggtcg tcgtggccta
     9781 tgcccctgtc atgggggact gcccgacgga cgacgggtgc ggcaacacct gcgcgggcaa
     9841 cgacagcgcc tgcaactcgt tcgcagacga tccgtcctga cccacggggt gctgccggtg
     9901 cgctacggcg caccagcagc acccctgcgg tcgcatcgtc acaggaggcg agacagtgcc
     9961 atcaagatca tccgcggtat acgtgcctgg cggtgcggcc gtgctccgcg ccagcaccga
    10021 ccccagcggg ttggatctgc ctagtgccct ggatttgtac ggcgatggtg ggatcgagcg
    10081 cggcatagcg tggttgacga tgcagtggca gcgggcggat gttcggaccg ccgtgggtta
    10141 cgcgagtccg gccctatccc gccagatcga cgagatggtg gccgccggta gtcgtgatct
    10201 ccgagcggtt cgtcgagtgg tcatctccct ggcgtcctac ctccttcgct ggcagcagcg
    10261 ccccaccccg ttcgggctct ttgccggggt cggcttggct cggatcggtg ctgcggccaa
    10321 ggtgcgttgg ggcttcgagc atcgagttgc cgttcgtgcg gacgcggcct ggctcggtga
    10381 tgtcatcaca cgtctgcatc aatgtgtgcc gctattggag cggatatccg tggtcgtcaa
    10441 caacgcgggc agtgttcgcg gtgatcggtt cgttgcacca gggtcacctc cggacggagc
    10501 gggccaagag ttggcgccga tcgaggtgtc cataggtctg ggccgaccag tccgagccgc
    10561 agtcgaagca gcccagaaac ctgtgcgatt cggtgctctc cgcgaacaga tcatggcccg
    10621 atttccagcg gcgactagac agtcggtcga caccatgctg acggggctgc tcgacgaagg
    10681 gatcctgatc agcagcttgt ccgcgccgat gacgtgccag gacccgctag accacgtctg
    10741 cacaaagctg gaggccgtcg aggccaagac aatccccgag gtcacgcata ccgtgcgcga
    10801 actcacgact atccgcgagc aactggccgg agaagccgtc gccgtgactg aaaccgaagt
    10861 cacaagacgg atgcaggcgt tgagcgccgt cgcggacatg cctctccttg ccgacacgat
    10921 cttggattgt gacgtcgaaa taccagagca ggtggctcag gaggcgcgcg acgccgtccg
    10981 agtcctgtat cgcctttccc catatccgtt ggggtatccg gcctggcgcg actaccactc
    11041 gcgattccgc gcacgctacg gaatcggtgc gctcgtgcaa gtcctggagt tggtcgccga
    11101 cagcggactc ggcctcccgg ctggcttcct tggctcctcg cgcgggcgca ccgctcatca
    11161 gatgagcgaa cgcgacgaaa agctcctcgc gatgatccag cgagcgacag tggacggcac
    11221 tggcgaaatc gtcctgaccg atcaggcgat tgaggacctc acggccagcg atcccgctga
    11281 cctgcacctg cccgctcgtg tcgaggtggc ggtcgagatc cactccaatg gtgtagaagc
    11341 gttgtctcgc ggccggttca cgttggcggt gactggaacg ccaaggccag gcagcagcat
    11401 ggctggccgc catgcacact tgctgcccga cgacggccgc gacgcggtcg ccgcctcctt
    11461 caccgcagcc gagcccggca ccgttgccgc ccagttgtcg tttacaccac ggaagcgccg
    11521 caacgagaac gtcgcacgga ccgagcagtt gctgccccac gtcattcccg ttgccgagca
    11581 ccatgagcgg gacgagcacc tgatcaacct gacagacctc gccgtcacgg cggacgaccg
    11641 tcggttctac cttgtccaga tatccaccgg ccagcgcgtc gagccgcgcg tgacccacgc
    11701 tctggaggcc ggcgtccaca ctccacctct ggcccgattc ctcgccgaga tcaccaccgc
    11761 ccgagcttcg gtgtacaagg cgtttcactt cggggccgcc gccaggctcc cgtatcttcc
    11821 ccgagttcga taccgacgaa ccatactgtc cccggcgcgc tggctgctgg cggccggcga
    11881 cctacctggc cgccgtgcct cgttcgctgt atgggaggcc gggctggacg catggcgaca
    11941 gcaatcgcgt gtccccgcct gtgtcgccct ggtcgaactg gaccggagac agccagtgga
    12001 cctgaaccac ccgttgcacc gactcctgct gcggacgcgc ctggaccgcg gaggccgact
    12061 cgaactgcgc gaaacctcgg gaccggcgga cattgcctgg cttggccgag ctcacgagct
    12121 tctcatcccc ctggtcctgg attccgctgc cgctgcaagc cggtcatcat cgatcgcagt
    12181 tccacagcag gttgtggcca gcgacgccag ccacctgcca ggagattcgc ccattctgtg
    12241 cgcgcagatc tacggacacc cagaccgctt cgatgaagtt ctcacggagc gacttcccag
    12301 cttgctcgga gccttcggcg atgtcgcact gaactggtgg ttccgccgcc atcgccagat
    12361 gagccgtccc gatgacgatc agtacctggt cctttacctg cgcctgcctc agtcatccgc
    12421 ctatggctcg gctgccgaac gccttgtcga gtgggcgagc acgctgcgca gcgaacgctt
    12481 gctgtcgcat gtcgcgctga ccacacacga gccccagaca gggcgctacg gtcacggttc
    12541 cgcattggag cgcgcgtacg acctgtttgc ggccgactcc gcggctgctc tcgcacagat
    12601 cgccttgact atccgaaccg ggacgcaccg acaggcggtg gcagctgcca gtttcgtcga
    12661 cgtcgccgtg aacttcgccg ggtcggtcca gagcgggttg gattggctgc tccgtgaact
    12721 tcgtcaacag cacgggcggc tgcagccggc gctccgcgac cgagcgctgg agctgactga
    12781 cccggaggcc gtatggacgt cgttgcgttc cgtgtcgggc ggggagaaag tcgtgactgc
    12841 ctggcagcgg cgcgccgttg cactcgcggc ctatcgagta gccctggccg agcagcgtga
    12901 tccactgacg gtgctgccgt ctctcctgca cctgcaccac attcgtgcag tcggagtcga
    12961 tccggcgctt gaacgcgtca caggccgttt ggctcgggct tccgcgcgcc gcgccgctgc
    13021 tcgccgcggg gagatttagg ttggctacca cggcgatcgc gctggccgat ctcgcccagc
    13081 ggcatgccaa caatttggca ctgccgggac catgcccaga ggacaaaccc tgggccgatc
    13141 aatctctctc caagggcacc gccggaatgg cgctgctgca catcgaacgt gctctcatcg
    13201 gtcgcggaac ctggcgcgag gcacaccttt gggtcaccaa ggctgtcgcc ggtcgagtca
    13261 gcgccacgga tacttccggc ctttatctcg gggctccggc agtcgcgttc atgctggacg
    13321 ctgcggcgac tggtgccagc ggtcgctacc aagaggctct cgcggatgtc gacggtcacg
    13381 tggtcgcgct ctctcaccgg cgcgccgaag ctgcgctagc acgcatcaag gcgggcgagt
    13441 tccctggatt ccgcgagtac gacgtgttct ttggtttgag cggcctcggc gcattgctcc
    13501 tgcgtcgcgc ctccgatagc agcgcgatgg agcgcgtcct ggactacctc gttgccctgg
    13561 ccaggccacg tcaggtcgat ggcgatgtac tgcctggctg gtgggtcggc cacgatcccc
    13621 accgtcgaat ctccgcctcc tatcaggagg gccacggcaa tttcggtctt gcccacggca
    13681 tcaccggccc tctggccttg cttagccagg ctatgcggcg agggatcatc gttgacggtc
    13741 agcacgaggc gatcatcacc atctgcgaat ggctcgattc gtggcagcag gagggcgcgg
    13801 ccggtccctg gtggcctgaa tggatcaccc tggcagagct gcgtaccggc cagcctcacc
    13861 agtcggggcc ggcgcgcccc agttggtgct acggcacgcc tggaatcgcc cgtgccggcc
    13921 aactcgctgg catcgccacc ggtgacgccc accggcagcg gatgtacgaa caggcgctga
    13981 ttcgctgcct cgacgaccct gagcagctag ctcggatcac cgacggcggc ctgtgccacg
    14041 gttgggccgg gctgtaccaa accgtctggc gatcggccca ggacgctgga acatccgcgt
    14101 ttgacgaata ccttccgcct ctggccgcgc acctgggtca acacactcgc cacgggccag
    14161 tggcgaagcg cggcttcctc gaaggcacag caggaacagc tcttgccctg cataccgccg
    14221 tgtacaacac cacgccgact tcgggatggg acgcatgtct actcatcgac tgacaccgcg
    14281 agaggtagaa ctgcgaagca gtgatgccga cgagtccgcg gttgcgcagg gcgcggagta
    14341 cggggttctt ctggtactgg ccggggcttc cttgaatgaa gccgcagcag ccattcacgt
    14401 cgaacccgcg gacctggccg aggccgtcga ggtctatcgg aaagctggac gacacgccct
    14461 cgaacggcag gcagcttcgg actggtggca gatctacatc gagttcatcg attggagcac
    14521 ggccgaacag tcagcagccg acaccatcgc gccgctgttg caccgagctg gagaggacgg
    14581 cctcgtcacg aagtggtggt tcatgaggaa acacccctgc tggcgactac ggattcaccc
    14641 agggcgggac ggacacgcga tgcgggacca tctcggggcc gcactcgatg aactcgcagc
    14701 cgacgaccgc attgcccaat ggtggcccgg cacctatgag gccgagatgc aagcttttgg
    14761 taactggacg ggcatggagg ctgcccacga tctattctat gaggacagcc gcgccgtcat
    14821 gcaccttgct cacaacggcg gcggcgggct gggccgacgc gaactgtcgc tgctgctgtg
    14881 caacaccctg atgcgcgcgg cgggactgga gtggtacgag cagggcgacg tctggcaccg
    14941 gatcgctcag gaacgcccac tgccagagga tgtctctgcc gcgaatctga ccgccatggc
    15001 cagcgatctc aaacagttgt tgctcgcgaa cacagctcct ggcgggccgc tgctacgcgc
    15061 agaaggtccc ctggcctcat ccgcagactg ggccagcgcc ttccgacagg ccggccggac
    15121 cctggggtcc gcggcccgta cggggacgct gcagcgcggc cttcgtgagg ttctgagcta
    15181 cctgatcatc ttccactgga accgccttgg gttgccagct cgaacacaga gcattctcgc
    15241 gtgggcgacg cgcaccgtca tccttggtct gcccggacat gtgccgccca acccgacatt
    15301 gagtggtgga cctacctctg ggacaacagc accgccattg gcggcccgag cgaacgaagg
    15361 cgtagccgaa cgagcactgg cccgatttcc gcttgtgtcg cagcgccgct ttccctgtcc
    15421 tgatctggaa acccaggtgc gcaacgtgcg cgagtgcgca aactcctgcc aggagtcaac
    15481 cactgtcgaa gagcggatga accgcgcctg caccgtctgg aatctgtccg cgcgcatcgc
    15541 ggccgaatgc ggtatgcccg acgtcgccat cagcctatgt cgacgacagt tccgaatttt
    15601 ccgagcagcg tcaccactgt cggccggttc tgccatcgct tcgctccagc cagtggtgaa
    15661 cctcgcccga ctgaccaggc gggcaggtga caaccaaggc gcctaccgcg agctcgaagc
    15721 gatcaaccac gccgtccgta atggtggtgc ggccgtgatc cacggtgact tggtcgactt
    15781 cgacggccta atcgcggacc gctcgtccga agtagacaac tggcttcggc aggttatgcg
    15841 tgaggatgga acccgcgcgc ttgtcgcagc cggccagtgg acgaacgccg cagcgcatgc
    15901 cgagaagtac gacgaaacca gaaatcagtt ccgcgaagcc cgccagacac gcgccatcgc
    15961 tcttgccctt aacgggaaag ccaacttggc gctcaaactt atcgacaaca ccgccaaaag
    16021 cgatgcttgg gagtacgccg gggcagcgtg cctgcgcagc tacctgcttc ttcaggagcg
    16081 cagcatcggt gcaggtgacg tgataggcat gcttaacgat gttcggcatg tctgcggggc
    16141 atcgcaccga cccacggggt tattccggat ccggctcggg ttgaccgcgg cagaccttgc
    16201 tgttgcggca caaggagatg cagggcttct ctgcgccgag ctgatcgaga aggctgaacg
    16261 atcggcagat gcattcatgg cgcgcgaggt gctggcacac ccagaatgcc aaacgctggc
    16321 tacacccaag cagagcgaaa ccttgggcct gctcgtcgag cgagcaggtt ttgactcggg
    16381 gcaggtcccc gcggtggtga tggacgacct catgtcatcc gtacacactg ccgaaaccgt
    16441 cctgatcgcg aatctcggcg tcacagccag ccgactgggg ccgatccgtg actgaacctg
    16501 aacacggtct agatcgaggg cttgccttgc cacacacctc caccgtaccg accggtctgc
    16561 tcgacgagct gcgcaatttc tatcggcgtg aaccgagcct gctcgccgac gaccttccgg
    16621 gcctgcggct cctttgaccg gggtcggaac aatcgtgtct tcgcctggga cggcccggac
    16681 tgcgaggtct gcctcaagct gtaccgcacc gacaaacgcg accgcgcggc ttgcgagtaa
    16741 caggccctcg cacatgtcgc ggcctgcgga gtcaccgctg ctccacagcc gctgtgacac
    16801 aaccccgacc ccgaactgcc tgcagtcgcg atgaccattt tcgccggtcg gccggtgccc
    16861 gacctcgccg agtccaccac cgcactttgg gccatggtcg cgattctcga ccaactccgg
    16921 gagagcccac tcggaccgtt cgctgacacg ccgcgcgtcg attcacccgc aaattacaag
    16981 aatcgggtca ccgaggtctg gccgggccag ctcgacgagt gcgaggacga gccgcttacc
    17041 gctgacatgc aattgatgct cggcccctgg tacgaacgag gcgacaccgc ggtgctcgcc
    17101 gatcggcgcc gaggatcgtt tctcgcggcg actctaacct gttcaactgg ctctggggcg
    17161 agccgaacgt ccacgtcgtc gactgggagt tcatcggtca cagcgacacc gtctatgacg
    17221 ccgccgagtt ggtcgaacac ctcagcgccc gcgtcatcga cgatgagtgg cgagtcgcgc
    17281 tactgccgga ccacggaatc gtcgacgaca cggcacgtcg ccgttttctg gccgcacagc
    17341 gaaccgttgc gctcagcttg ctgtggaagc gtggagacaa gcgagccgat gatgtcgagt
    17401 ttcaggtcaa gtgggtccgt gagctgatga acagcagctt cctgtgacac acctggcttc
    17461 agtgtcgcct catgtgcgct atcccgacgg gccagtgccg tgaacgccct gccaatcccg
    17521 cgcttgccgc ccagcccgct gttcagtgcc tcgacctcgg caggttgccg ttccccgcgc
    17581 cagacacccg agtacgaggc actgaccgaa tacttgccat gtgtgggtga gctcgacgcc
    17641 cccaggtgtg atgtgacggc caacgccaag agtgtcgagg atgagcaggc ggcagctgcc
    17701 atcgctgcac gacctcagcc ccaccccagc cttgacctcc tcgctcgagt cctacagggc
    17761 ctaagagaac tgtgatcaga gccagcgccg tccctcgatg ctgacttgag ctacgcagtg
    17821 cgggagggcc ggcgttggag ccgtcggtaa ggacgagtga tatgtaggct tcaaccgttc
    17881 cgtccccgac gggactgctt cgacgaactt ggcgttggga gggtgcctgc tcatgggcga
    17941 gctaggtgtg atccgcaatt acgcctactg gtcggatcgc cgtatccggg acatcgcgtc
    18001 agacaacggc atccccctcg aacgacgcgt gagttggaag gccaagacgg cttttccgtt
    18061 gatcggtggg ctcgaagttg ctccggaggc acgcacgcta gaccgtgccg aagtggcgcc
    18121 caggatcgag acggcgatcg gcgaccttgc agttcaggac ttcgtcaccc cgccaccggt
    18181 gatgttcgcg aagggcgtcg gccgggtcga gttcgcccag ttcacgggtg gcatcgagaa
    18241 gcgacaggtc gtcgtgatct acaccaacac ccgcagcagc actgggagtc gcgtcgacgt
    18301 gtgcctgttc ggcagcctgg agaacaccgc cgactacatc ggcggctccg accaaccacc
    18361 gccaggatgg tcgtcctccg cagctcggac aattgctctc tacatccaga gccgaggaac
    18421 gatcaacaac tcgcagtggg acgacccgga gtccctcgca gtcgaagccc tgaagatcgc
    18481 aacagagcag ggcgtgaccg gaaactggga cgaacacgag aacaagccct ggacgcgggg
    18541 gttcacactc ggccacacga ccgaatccga gtggttcgca cagatctaca gcgacgtcgt
    18601 gctcgacaaa gaccggtgga cctttcccag cgacggcggc atcagcccag acgtcgagcg
    18661 catcctcatc ggcgctccat tgtgggtacg gactccgggc gcacacgccg tcacccgcta
    18721 ccgcgaccta cgctcaggga gcgacagagc aacatgacaa gggactcctg cctggcctgg
    18781 atggccacca ctacgccttg acggacacaa taatcgagtg agcgatgact gggagcagcg
    18841 ctgggcatcg ggagcccgga cgttctacat cgccgagatc gtgcggcagg cgagttacgc
    18901 cttggcggcg gtgcaacagg cgcttcaact cagccgggat ccacaggggc gttccgaggc
    18961 gtggccggca gtccaatcgt tcctcactgc gactgccatc atcagcaagt tgttgtggcc
    19021 cgtcagagcc gagagagccg accgcaagtc ccgttggcgt cgctttcgcg cagatcgact
    19081 gcggaccgag ttgatggtca gcgacacctc ggccctgcgg gacaggaagg tccgggactc
    19141 cgctgatcat ttcgacgaac gcatcgacga ccttgtccgc gaccagcgca tcccgcaggc
    19201 gtggacagac ctggcggacg aggagctcac gcaacgggca gccccgtttc gtgcgatcga
    19261 tgctgatacc ggggaggtgc ttgcaggcca tgaccgaatg gccttggcgc cagtcgtcac
    19321 cgagctgaac gcgattctgc aacggtgcga aaccatcgag cccggatcct ccagtgcccc
    19381 cgacgtcacc atgctgctgg ccacgctgag gtggccgccg ctgccgtccc tgttcgcgcc
    19441 caccgagcgc tccgacgaac cagtcaccgc cagggccagt atcgcggcga ctggccctca
    19501 gaccctggag gggttgatca cgctggttat cgatcagctc ttcgagcatc cggacacgaa
    19561 ccgcacccgg cgcagaaaac atcggtgacg tcaggccggt ccagctggca tgctggttac
    19621 gtaccgcgat caagtgcgaa cgcacggtga gtgtgcctgt gagcatatcc gtgagcatgc
    19681 ccctggctct caccagacca tcagttgttg ttgtgtaagg tatccgtcac gagatgaggg
    19741 ttatctgtaa ccagggtcgc taccgatacc gcggtatgcg tcgcttcggc catggtgagg
    19801 gacatctgct gccaaccttc gtgcctgctg tctcccggtt tcgccgaccc tgtcacctga
    19861 aggtggtaag cagatgaagc gctgtggcgg ggacggacgt ggtcgcttcc tcaagaaggt
    19921 gctcgatcgc gttggcttcc ggtgatctgt caacatcgat catcttcgac caagtcgccg
    19981 gctggtaccg cgccaacgac gacagcgcta gcagtacggc ccacaacgct aagaatgggt
    20041 gaagaccggt cgccatagat ccgatcgcgg gagtgacgag agagtcgtcg gcggaccggt
    20101 agcacgcgac cccgaggtcg ctgaacgtct tgttgtcagc gagcatcaac ggcggcgagc
    20161 cgctgcgcca ctcaacgctc agccccatcc caggacccgc attgcgccag cccaggccac
    20221 ccatcggttg cgatacgtgc agcacgctgt ctcgcaacgc cgggtagcga tcgagatgct
    20281 ccttgacccg cactgggtct tgaccgaaga ggtcatgcac tcgccgcgga agccagttga
    20341 cctcggcgtg ggcgaaagtg ccgatctcag gccacccgtc ctggaagaac aacagaacag
    20401 gcaccatgac gtcgtcagtg agcgggacgt ccactgtctc cggcagaagc ggccacaact
    20461 ctcgtagagc aaccggctca ttggggacga gtgcctctac atcgatggcg gaagcgacgg
    20521 ccgggaacag accagacttg gtggcggtaa caaggacctc tgccgcagtt gcggtattgg
    20581 tgttggcggt caagccatgt ccactgacct tcgacacctg gttaccgatc cgcggtgatg
    20641 cagcaacaat tgcccgacct gcctgcgaca gggcatagaa caactggact ggccgagtgg
    20701 cgtaaccagt gtcactggct gcgtccagga attgctcaca ttgctccaac gctgactgga
    20761 acgtcgttcg ccgcgcaccc tgcttcgcat accccggtgg gtcgtgacga agagcccgga
    20821 gactccgcaa cttccgtccc gcagccgaca cagcgacctc cttcttagtc gcaccaaggt
    20881 acaagtaccc cggtccatcc gctaatcacc gacaatctcc gcctctcacg ggcacgctga
    20941 ctcgtcacgt tgcccgtcat cggtcttgcc tatcggtgcg tcaatggtcg accaacggaa
    21001 ctcgtaacgt gccactaggc tgtcgatccg tgtcgttcag cgcccgccga gcgccctgac
    21061 cgcgaccacc agccagacat cgacagatgc ggcgcgactg tccaaggcgc cgtgtcgctt
    21121 ccgttgagcc ccgacgcgca gcggcagagc ttgctggact cgtcgatagt ctctccctcc
    21181 ccgggcttct aacacagaag ggagaggatc gcgaagctgg ccgcgatttc ggcaacggag
    21241 acgtcatgca tctgtcctac gatgttgata gctgcgtcat gaggcggacg tccacatgcg
    21301 cagttgctcg tggagaacaa tgacggcctg ccaccatgga acgacctgct cgacgatggc
    21361 ggcgaatacg tccgcgacgt ctatgaggag atgcacgacg ttctcggcga catccctagt
    21421 ggaatagggg tacagccggg cgcaaggacg cgtctgttcg tccactcaga tgagttcgac
    21481 acccgagtgt ttgatttcga ccgatgtcgg cctgctggca caaggggaag ccagccaact
    21541 tccgcccacc tcgatgatca gtttgcctgc tcctgctccg ggaaccctgc acggaaacgt
    21601 gatcggaggc agtaatgggc agccagagca ctcatgggtt caaccggctc tcgaacaagg
    21661 cgagttcgtg gctggcgcat ccgctgtttt tcggcttcgt ggtgctcgcg ctggtggcgt
    21721 gggtgccgac attgtggctg atggagaccg gggcgtccga cctcgtcgtc gactccatca
    21781 ccaacccact gcaactgcta ctgctggttc tactgcacaa taaccagcac cgggtgagca
    21841 aagcgagcga cgaccgcgcg gaccagacag cccgcgcgct ggcaacgctt cttgaacacg
    21901 cagcaaccac gactcaagac gaacaacggt cgcagcagct ccgcgaggag gcggtacaac
    21961 tacagcgtga cgccgagaaa gacaacgaac tcagcagcgg tgacacacag cgccgcgaat
    22021 gacgacgcct tcatactgac ccataacact gtgggcaacc ataaggggca agcaaggcca
    22081 gcgagcccac gcacccgaac accctgacag tgggatgaac gagggaaccg ggctcgacat
    22141 cggttggtcg cgttctggtt ggcactccct cgaggtgctc tgatgccgga gccggatcgt
    22201 ccggacacgg tcaccagctc tcggccgtgt ttacctggga actgtgtcgt ccgcggccct
    22261 gacgttggcg ttgtggagga actgctcgtg tgtgtaggcg tcgtagatgg ctgcctggac
    22321 gaggcccgta tttttcgctg aactgctcgt agctgaaata ttttcaacgg ttccggtcgc
    22381 agtgacgatg ccgccctcct tgaagttctt cgccttctgg ttcagaagta ccagcaggta
    22441 gttgtcgccg tagacgccgg cgttgaggac aagagcgttt tcgttccccg gatcgttcac
    22501 cgccaacgtt aactcgattg tgcagcaccg gccgcgactc gtgacggtag gcgcgagttt
    22561 cacgttccgg cttcgaggga acatttttct tgctccggct agttctgtct tggtggcagt
    22621 gttaatacgt tcgagctgca cgtctccagt ggacggtcag gcggctgacg gccacgctgc
    22681 tgtgcaggct cagggtcacc acccgcacgg aggcggcggc cctggcgggg cagtcgtatg
    22741 tgctggacga ggtcgcacaa ccaccgggtc acccagcggc gggctagcgg tcgccgatca
    22801 ctcgcccccg atgcggcggc tctcctccag gtccttctcc cgttcttgct ggctcttctt
    22861 cgggatgatg ctgatgccgc ccgagctctc cagcacggcg tactcgatct ggtccagccg
    22921 caacaggcct tggctcttcc tggctgacgc gaggatgtcg tcggtgctga tgtgttcctt
    22981 gcgcaaccgc tcctgcagtg gcttgccgtg ctcgaccagt accagcgggg cgccttcggc
    23041 cagcctgctg aacgccgtgg agcgggactt cagcatgtcg gcgacgcggt cgagcaccac
    23101 gagggtgaga atcgccagcg caccgtgctg ttcggcatcc tcaccccggc tcccggcggc
    23161 gggttcgagg tcaccctcgc cggcggcggg cacccacccg cgctgcggtt gcatgacggg
    23221 gaggtggagg agatccgacc gaagggcggg atgctggtcg gtgcgctgcc cgatgccggt
    23281 tcaccacctg ctacctgcac ctggagcccg ggcagaccct gctgctctac accgacggac
    23341 tcaccgaagc ccgccccgac ggcgccttct tcggcgagga cggactcacc gcgttcctca
    23401 ccacccgccc ccgcaccctc gccgagcagc tgatccgcga cctcacccac ctcatcaccg
    23461 acttcgaccc cccacccacc gacgacatcg ccctcctggc gatcaccgtg cccaacctaa
    23521 gtccccagca cccggacgaa cacgcacccc aacgccaacc acgccaagcc ggaccagttc
    23581 cccggtaacc gcagacagga atcctcgaac ccgtctgctt cgccgtcggg cctacccgtc
    23641 gttggtcatc gtggcgtccg ctcccgacat cggtcggcac cacatggccg tgaccgcact
    23701 cgtagtaccc gcagacgatc cgataccggt gacactggtg gctgccaatt gggaaggtca
    23761 ccgcgggccg cgaggacata caccggaccg gcgggtcaca actaaccgga aaaaccgaag
    23821 agcagcaggc gctggtttgc ggatcgccgc ccggccgccc tactgggatt tcggcagcct
    23881 gaacttcccg gcctcgactc cgccgatgaa cgcctcccat tcgccctggt cgaagaccag
    23941 gacgtacccc tctgggttct ggctgtcccg caaaccgacc gcgttgctgc tgaaggacac
    24001 ctcgacacac tggttgtctg gcgggttact caggggcgac ttgtgccata cggcaaagtt
    24061 ggtgtcgagg tgacgcttgt gggcatcttg gatgttcatc tgctccctcg tacccttccg
    24121 atctcaagcc atattccagc tacaacgacg aggcgatgcc gagcaatgcc cgccgcgtct
    24181 gctcgggccc gctcgctgcc gccttctggt ggtcccagag agtcagatac cgcgccgtcc
    24241 gcttgctgtt gtcgacgtac tcgccaccgt catgctgctc aaggtagatg atgtcaaccg
    24301 cgggcttcgt gtcatagccg aagatcgtgt agtcgtgtcc ttggcccatg tagtagccaa
    24361 cgccgaacgg cacgacttgc agctcgacgt tcggccggtc gatggtctcc acaagccgct
    24421 taatctgggc cttcatgacc ggaccaccct cagtcctacg cagcgccgcc tcgtcgatga
    24481 tgaaccagaa ctgctggtcg gcgttctcaa gtacacgctg ccgagccagt cggttggcgg
    24541 cgtacttgtc gatctcgtcg gctgtcagcg agggccgcca tgctcgggcg ttcctgcgca
    24601 tgtagtcctc agtctgcagc agtcctggga tcaccagagc ttggtaggag aagtaccggt
    24661 tgcaactcgg ctccatgtcg accagcaacc gcaggtactg ccggaacctc gtgctgaagg
    24721 ccccgcgctt cgtacgtcgg ttgctctcgg actgaagatc tcgcgtgtag gcccggtcag
    24781 cctcgttggc ggcatagcgg tcgagcaacg cattcagctc gatcagcttg atcccgctcc
    24841 caccctcgat gtgcgcgatc ttctgctggg tgcatccgag gacggccgcc gcatcctcct
    24901 gcgtgacctc ggcgagttcc cgcagccggg ccagctgatt gccgaggacg accttcataa
    24961 ccgccggcgg caactgcaag tgctgcgtca cggattcctt cacctccaca gaatgtccgg
    25021 ttgcggagcg tatccacaat tcacccattc ggccagctgg ataatcggag tacacaagtt
    25081 aatatctaga tgcaacctag ccaggttacc aggtagcgaa ggggtgcgga gcgatgagta
    25141 cacaagctaa catcgccgct gcgacggccg cggttgcccc cagtgccgta gaagccccca
    25201 cgatgtcgtg ggggtctggg ttggcgatcg cagcggcact ccttctcatg gtgggctgcg
    25261 tggccggagc ggtgccggct ggtggtactt cggcgagcaa cgtcggatcc ggcagtgctg
    25321 cgaacaagtc ccaccgagcc gagccccgag gcaccgcaga cgacgcaagc cgccctcgcc
    25381 tcccagggcg tcgaccttcg cgttgcccgg ccacgcagcc ccccggcacg ccgagtgact
    25441 ttctgactcg acggcttacc gcccaccaac gctcacacgc caagcagtcc taggacgcag
    25501 tgcaacccgc gttgcctgac ctcctgccca attcagagga ggtggctcgc cgtgacaacg
    25561 tcgaccactg gtggtccagc tacacgctcg gattcgactc ccgaggaacg gtgcaccttc
    25621 tatcgcaaca agtgtcggct tccagccgtt gtcgatcccg cgacgcagcg catccttttg
    25681 cctgtcggcg gactcgttgg cgcgatcacg atgccgctac accttggtcg gcgtgtgctc
    25741 gccggcctgc ggatccggat gctggcaggc ccggtcgtcg aacggcccca catccagcgt
    25801 tggaccttca tcaccggccc cggccacgac cttgacgaag tcgtctccgc tgatctgctc
    25861 cggctcggag catcggttgc tgcgcaagga gacaacctcg ttctgccgac ccccgaggac
    25921 gaaagaatcg gactgtggcg ctgggagtgc gtcccgcagg catcaggtgg cgtcccgccg
    25981 cagtctgccg tgatcgctac cacgagagcg atggcgactt cgaccgtgca gtgactgatc
    26041 tgcttgtcct gcagcaacca agaattccgg tggtccggcc cagacccccg acgtggatcg
    26101 ggccaccggt tcccaaccct ctccctgtat gcgaatcgag gtgcacaggt ggttacttgt
    26161 ctgatcgatc gtcatagcga gccggatggt tggcgttacc gtcttcgaca tacaccgagc
    26221 gttcactcgg gtgaccaggg tgctcggcaa gcgggacccc aggtcgttaa cttgcgtgtt
    26281 ttggattgct tgccgccgca aacagaggtt gatctccttc ccgatacgaa taggaaggac
    26341 ggcgaagcat ccgctactac gcagctcggc aacggtgacg accatcggga cccacagttg
    26401 cttgatgctg tccggggagg aaacgttgcg gcttacggcg aactgtacaa gcttcatgtc
    26461 ggcgcggctc gcaacctggc tcgccagctt gccca
//
