LOCUS       NZ_LT629789            20687 bp    DNA     circular CON 13-MAY-2024
DEFINITION  Amycolatopsis keratiniphila strain FH 1893 chromosome I.
ACCESSION   NZ_LT629789
VERSION     NZ_LT629789.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900105855.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 02:01:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,886
            CDSs (total)                      :: 8,813
            Genes (coding)                    :: 8,742
            CDSs (with protein)               :: 8,742
            Genes (RNA)                       :: 73
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 26 of 71
            Pseudo Genes (incomplete)         :: 51 of 71
            Pseudo Genes (internal stop)      :: 1 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:07:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7253874
            Orig. end                         :: 7274561
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT629789.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20687
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="26"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20687
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20687
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10687](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10687
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(119..916)
                     /locus_tag="BLU53_RS33115"
                     /old_locus_tag="SAMN04489733_6778"
     CDS             complement(119..916)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632041.1"
                     /locus_tag="BLU53_RS33115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6778"
                     /product="ABC transporter permease"
                     /protein_id="WP_063275543.1"
                     /transl_table=11
                     /translation="MTTIAAPAPRRVSLSSSTRHGLSLAWRGILKIRKNPEQLADVTIA
                     PIIFLVMFVYLFGGAIMGSTEGYLQMIVPGIMVFNILQASMTVGVQLNTDVTKGVFDRF
                     RAMPIARSAPLIGAVLADIVRYLVCLVVLMVVATIMGYRVQTGPAEFALAILLVIAFAL
                     SFCWASVFVGMLVKSPGAVQGLMFVVLMPLTFGSNVFVPTGTMPGWLKAWADISPVTQM
                     SDVLRGLMNGGPIAGPLTGSLIWMAAALAVFFPLATWAYRKRV"
     gene            complement(913..1890)
                     /locus_tag="BLU53_RS33120"
                     /old_locus_tag="SAMN04489733_6779"
     CDS             complement(913..1890)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028550.1"
                     /locus_tag="BLU53_RS33120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6779"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_072029677.1"
                     /transl_table=11
                     /translation="MTHAIRAEGLVKHYGETKALDGVDLEVPAGKVVGVLGPNGAGKTT
                     AVRILATLIRPDRGHASVFGYDVVKNPMAVRSMIGLTGQYASVDEDLSGTENLVLIGRL
                     LEFSRADAKQRAAELLERFELTDAAGRAIKTYSGGMRRRLDLAASLVGRPKVLYLDEPT
                     TGLDPHARNEVWAVVRTLVADGTTVLLTTQYLEEADQLADTITVFDHGHVVANGRADEL
                     KRRTGGQTLQVRPSALADLDAVERILAGLTGARPNRDDDTGLLTAPVADPVLLSTLVRK
                     LDEAGITADELALRLPSLDEVFLALTGKKTDESTKDTTPEGSLV"
     gene            2018..3046
                     /locus_tag="BLU53_RS33125"
                     /old_locus_tag="SAMN04489733_6780"
     CDS             2018..3046
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337750.1"
                     /locus_tag="BLU53_RS33125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6780"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_083715536.1"
                     /transl_table=11
                     /translation="METAAPARVIGILDGMVIEERPVRPAARPGTGRKLVSGLLIAAVV
                     PFAVLTALRLVGYDGNTYTIAALALTPYAGIATFVLAVLALVLRRWWTAAVALVLTCTI
                     ASMVLPRAFANEQKALDGKHVRVLASNMLGGGADPARIVGYVKEHQVDVLSLTELTPEA
                     ITALDRAGLFQVLPYRVLHPAEWASGSGLVSKYPLTPLKLSGDSDYKQPSASVDLGDGV
                     RVEVVAVHPSAPMWDRYEWVAEAKDLPYADAEHDIRILAGDFNASLDHALFRELLTRGY
                     VDAADELGKALQGTWTNGIAPPVAIDHVLADKRTAIADFKVLETPGSDHDAVYAEIVLP
                     GK"
     gene            complement(3323..4135)
                     /locus_tag="BLU53_RS33130"
                     /old_locus_tag="SAMN04489733_6782"
     CDS             complement(3323..4135)
                     /EC_number="2.3.1.286"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337749.1"
                     /locus_tag="BLU53_RS33130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6782"
                     /product="Sir2 family NAD-dependent protein deacetylase"
                     /protein_id="WP_072029678.1"
                     /transl_table=11
                     /translation="MSELERAAELIDGAGALLVCAGAGMGVDSGLPDFRGDEGFWKAYP
                     PYERLGISFVELADPRHFAEDSELAWGFYGHRLALYRATVPHDGFRLLLSWGARKPGGT
                     RAFTSNVDGQFQKAGYPQVAEAHGSIHHLQCLDRCSKEIWPADGVEVPIDEDTMRAQAP
                     LPSCPRCGGLARPNILMFGDYDWLGQRSQAQLDELNAWRRAHRDLVVVELGAGQAVPTV
                     RRYSELASAATGALVRINPREPGIRHGRGVSLATNGLETLEALDALLG"
     gene            complement(4128..4436)
                     /locus_tag="BLU53_RS33135"
                     /old_locus_tag="SAMN04489733_6783"
     CDS             complement(4128..4436)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084240.1"
                     /locus_tag="BLU53_RS33135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6783"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_038520818.1"
                     /transl_table=11
                     /translation="MAVVKINAIEVPEGAGPELEKRFAARLHAVDDQPGFLGFELLRPV
                     SGESRYFVYTKWESEEAYQAWASGPAREAHAGERAKPVSTGANLLEFEVVQASKPGE"
     misc_feature    4453..4464
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.15"
                     /tool="antismash"
     gene            4498..5688
                     /locus_tag="BLU53_RS33140"
                     /old_locus_tag="SAMN04489733_6784"
     CDS             4498..5688
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680387.1"
                     /locus_tag="BLU53_RS33140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6784"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_228708093.1"
                     /transl_table=11
                     /translation="MADTKILISGASVAGLALAFWLTRYGFQVTVVERAPSLRPGGQAV
                     DLRGTAKEVARRMGLDERIRAACTDTKGETLVDRKNRTKATIRADDFDGDGVVAEIEIL
                     RGDLTEVLYEATRERTEYVFGDRITALDERADGVGVTFASGSRATFDLVIGADGLHSGV
                     RALAFGEESRFVRHLGSYLAFFTVPNRLGLRNWAVGYDDVGRSAGIRAVRDGDEAMAYF
                     GFASPKIDYDYRDVEAQKALVRRFAAGMEWEAPWLLDRMDEAPDFYFDSCAQVIMDSWS
                     RGRVGLLGDAAFCPSPLSGQGTSLAFVGAYVLAGELAAGLDTGLKRYEAVMREFVEKTQ
                     ELGRENAESIFAKSRTGLRMRYLAMRVMRLKPFAALASRKMRDVVNGIDLPDYPRV"
     gene            complement(5778..7220)
                     /locus_tag="BLU53_RS33145"
                     /old_locus_tag="SAMN04489733_6785"
     CDS             complement(5778..7220)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028556.1"
                     /locus_tag="BLU53_RS33145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6785"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_072029680.1"
                     /transl_table=11
                     /translation="MCSRVPAAGLVLGVVCALIIGCSADPPPATPPPPPPMNPAPGAPG
                     AGDPYYPMDGNGGYDAAEYQVGITYDPAKGRLDGDTTVIAKATQDLNRYNLDLRGLTVQ
                     SVEVDGKPAKFTREGEFELVVTPAEPIRNGTSFRTKVLYGGDPSATPKAGGSENGWQKS
                     KDGGAFIVGEPHSASFWYPVNETPRDKAMFTLTARVPDGWTVISNGREIQKTAANGWTT
                     TSWQERTPVAAYLTTVAIDKFTVDRMALPDGTPVVNAYAPGAEDRRDTGRRLPEIIGFL
                     SSKFGPYPVDAAGGIYLDEDIHFSLETQTRPTYAKWADLITVVHETAHQWFGDSVTLNS
                     WSDICLNECLASYAQWLWQESRDNEDLDVRYRAALEIMRGSTDFWKPKLVGMGAGQEFR
                     GVYDKGILAVHALRRKIGEGAFARLLKEWPAAYRNANATWADFEAFTIKLSEQDLRPFF
                     DAWFHGTTIPPDAELLPGTLRG"
     misc_feature    complement(6927..6929)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7219..8016
                     /locus_tag="BLU53_RS33150"
                     /old_locus_tag="SAMN04489733_6786"
     CDS             7219..8016
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-117). E-value:
                     6.4e-23. Score: 73.6. Matches aSDomain:
                     nrpspksdomains_BLU53_RS33150_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337745.1"
                     /locus_tag="BLU53_RS33150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6786"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_144024047.1"
                     /sec_met_domain="PF00561 (E-value: 5.2e-18, bitscore: 64.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.8e-18, bitscore:
                     66.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGSLVVIQRDGLVTFGGDGPPIVLLHGLMGRATTWWQVARRLEP
                     YGRVHGLDARGHGRGPRGGPWRTERFADDVAEVLRTFGEPAVLIGHSMGGLHAWVTAAT
                     HPELVRAVVCEDFAPDQRGRTVDTWRGYFESWPVPFRSLAHVREFFGDTGDYFIECVEE
                     REDGYHLIASLTDLYEIAAEWGRRDFWEFVERVKCPLLAIEGERTAMPPGQQAELAARV
                     PGGLGRHIVVQGAGHVVHDEAPETYLGAVEAFLSDVIGQPFAS"
     misc_feature    7231..7233
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        7279..7569
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU53_RS33150_Abhydrolase_1.1"
                     /evalue="6.40E-23"
                     /label="BLU53_RS33150_Abhydrolase_1.1"
                     /locus_tag="BLU53_RS33150"
                     /protein_end="117"
                     /protein_start="20"
                     /score="73.6"
                     /tool="antismash"
                     /translation="PPIVLLHGLMGRATTWWQVARRLEPYGRVHGLDARGHGRGPRGGP
                     WRTERFADDVAEVLRTFGEPAVLIGHSMGGLHAWVTAATHPELVRAVVCEDF"
     CDS_motif       7471..7527
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU53_RS33150_0001"
                     /evalue="2.10E-04"
                     /label="NRPS-te1"
                     /locus_tag="BLU53_RS33150"
                     /protein_end="103"
                     /protein_start="84"
                     /score="13.9"
                     /tool="antismash"
                     /translation="PAVLIGHSMGGLHAWVTAA"
     gene            complement(7998..8432)
                     /locus_tag="BLU53_RS33155"
                     /old_locus_tag="SAMN04489733_6787"
     CDS             complement(7998..8432)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337744.1"
                     /locus_tag="BLU53_RS33155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6787"
                     /product="thioredoxin family protein"
                     /protein_id="WP_063273490.1"
                     /transl_table=11
                     /translation="MSKVKRFVCVLAGALALVTGFGGGVASAAPTAENVMTVTSANYAE
                     VMNISKQKLVIMDFGATWCPPCRQMKPVIERLAGEYGGRFLLGEVDVDQSRDLSTRYNI
                     RYLPTLVGVRNAAELPSSRNIGYPGEARLRAWIDAQLAKG"
     gene            complement(8445..8795)
                     /locus_tag="BLU53_RS33160"
                     /old_locus_tag="SAMN04489733_6788"
     CDS             complement(8445..8795)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028559.1"
                     /locus_tag="BLU53_RS33160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6788"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_016337743.1"
                     /transl_table=11
                     /translation="MLPLITRTELLSRMESGSVVVVDTMPVAYFEKEHLPEARNIPGFP
                     YEQAAEFTDRLAPTVLPDKGAAIVVYCANTPCRNSEFVGRRLLELGYTNVRKYREGIED
                     WVANDLPTWSSS"
     gene            complement(8888..9841)
                     /locus_tag="BLU53_RS33165"
                     /old_locus_tag="SAMN04489733_6789"
     CDS             complement(8888..9841)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337742.1"
                     /locus_tag="BLU53_RS33165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6789"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_072029681.1"
                     /transl_table=11
                     /translation="MEIQVRHLRVICAIAAAGSLNRAAAGLGLGQPALSHQLRRIERMV
                     GGPLFHRDQHGVRPTELGALILRRARAIVLTFDELEHDFHRREPETGESIRIGWNDSAI
                     TGSLLGGLRDLRPGEPFRTRADTSRTRLLAQVANRGIDLALIMICGRRGLPVPPEVRTL
                     TLVEEPSFVAIPAEHPLAGEEEIELAELAGEDWIVSSGGDGCRVVFREMCLAHGFDPRI
                     THDVDIDTAREDLVSGGYGVGLVQPTRPPADGLAIRPLAGAPMCVRHVLAWREDGPCAR
                     GVPELATEARAGYWRLAERTASYRSWLHRHGRVAAG"
     gene            10001..10687
                     /locus_tag="BLU53_RS33170"
                     /old_locus_tag="SAMN04489733_6790"
     CDS             10001..10687
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337741.1"
                     /locus_tag="BLU53_RS33170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6790"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_072029682.1"
                     /sec_met_domain="CDPS (E-value: 4.3e-78, bitscore: 260.9,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPLPLTEHCADPLARAEHVCLGVSPFNSHFTVDRIADLARWAM
                     SAFREFHFFVPDGPSAFTLEALGYDPVRAAQKAQRQGNYTRNKIVRALQRVCPSDPHTL
                     ILDASVLEADSAYLGLLSEAHQRFATDPEFAEQCLGATGWVLDRRLPEGEHPTRDQLRS
                     AVRYFLAELPMFVGTVAVAGVESSVFAYHQRVGFLERLYRGELSWRPLPGQGFVILEQA
                     VPEPVE"
     gene            10690..12003
                     /locus_tag="BLU53_RS33175"
                     /old_locus_tag="SAMN04489733_6791"
     CDS             10690..12003
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165331.1"
                     /locus_tag="BLU53_RS33175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6791"
                     /product="cytosine permease"
                     /protein_id="WP_072029683.1"
                     /transl_table=11
                     /translation="MEHDDFSLRRVPADRRYSWVSVALQRFGQVSSFHQFLLGAVLGFG
                     MTFWDAVLAITIGSVLLEIITILMGIAGTREGLSTSVLARWTGFGTGGSSLVGLLMTVS
                     LAGWFGVQNDVFAHGLHALMGGPPVWVWALAGGALVTAIVVFGFHAMAWTAYLTVPAFL
                     ALAGFSIISALGDHSLPVLMSGPPPGPAMSLAQGTTLVAGAFIMGAIMTPDMTRFNRTA
                     SDVVKQTLVSVTLGQYLIGLIGVLLAHAAKSADVVGIITSSSGVLGTLILVTAILKIND
                     WNLYSSSLGLVNAVQVLLSRRLDRTTATLLLGGLGTVLSAIGILDHFTTFLTWVGVLTP
                     PVAGVVIAEYYVVRRWKPELEAGRASGELPSTCPSWVPAALICWAAGAAVGIWLPWGIP
                     TVNSVFGAFLLYVLLGRRTTAAAAPAATTSSGGSKTRS"
     gene            12000..12980
                     /locus_tag="BLU53_RS33180"
                     /old_locus_tag="SAMN04489733_6792"
     CDS             12000..12980
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337739.1"
                     /locus_tag="BLU53_RS33180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6792"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_072029684.1"
                     /transl_table=11
                     /translation="MTKEFDVVQLDVHHLRVIRAIADTGSLSRAAIALGVTQPAVSAQL
                     KRLENMLGYQLFDRCEGGVTPTPMGELLLRRTAALLPQLDKLLEDIEQRVCPSGPPAVV
                     RVAAVASALVACLPSLVTRLWPEVSEVQVVHDDHPERLLPLLAQRRAELALVKDYPGYE
                     LEIPANVDTAVVVTEPTFVLLPASHPLAREKVVDLRDLRDESWVMVSDSSAATFTKYFA
                     DTCARHGFTPTFTHQVTSQQVALLVVKAGAIGLSQPICDPGDHGIVTRPLRGDVLPRRH
                     VLAWNKETFVAGRRDELLSAVVDAYWAEARTAPVYAEYLDRPREW"
     gene            complement(13212..14651)
                     /locus_tag="BLU53_RS33185"
                     /old_locus_tag="SAMN04489733_6793"
     CDS             complement(13212..14651)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337738.1"
                     /locus_tag="BLU53_RS33185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6793"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_072029685.1"
                     /transl_table=11
                     /translation="MTVRIRWQEPLCTALLATTMLGACPASAVAKPAPGSDGYVHVSPD
                     GTVLGPDPYYPKDGNGGYDVDRYSLALDYAPYSMFLSGKATITATATQDLDRFDLDLRG
                     LTVRSVTVDGVAAAFRREGEHELVITPRTPLANGARFTVVVGYDGRPEPIPTARGRVGW
                     LAAYGDSAVATGQPRSAMTWFPVNGTEVDKATLRVSVTVLDEFSVLGNGSQVSDVPAGV
                     GRHTVTWSEETALAPSTAMLGIGRWEVERITLPGGRTAINAYHPCAVDKRKIGGRLPEV
                     LEFLTGKFGDYPQSAAGGLFLDRSLGYTHGAQTRPVYGRTATIADLVYASAYQWWGAGV
                     SGKMWRDALMPESIARYAVWLWDEKNGVDPDRRYREMVAKVRDDAAFWAPKLTDPGKGT
                     EFAPTAKAVLMVHALRRLVGDDAFFQILAGFPVINPQGNQNWHDFELYVSAMTQRDLGE
                     FTHAWLDGTVRPPDSLLFPGS"
     gene            14819..15973
                     /locus_tag="BLU53_RS33190"
                     /old_locus_tag="SAMN04489733_6794"
     CDS             14819..15973
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337737.1"
                     /locus_tag="BLU53_RS33190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6794"
                     /product="MFS transporter"
                     /protein_id="WP_063272659.1"
                     /transl_table=11
                     /translation="MLPLPALLALTTTVFLGCLTEVLPAGLLLGMSEELGVSPSATGQL
                     VTVYAITTALTAVPLTGATLRVPRKRLLLVLIFGFLATNLVIAVSSSYPLILATRVVSG
                     ALTGVMWSLVAGYAMRLAPAGLTGRALAVAMSGTPIGFALGVPAGTALGEFADWRWAFA
                     AMALISVPLLAWVSVAVPAVPAERTEPTRPLAASRLPGMRPVLATVALFSLGHNVAYTY
                     IGPVFAGLGVERMLGAALLVFGCATVGGLVAVGSALDSRPRAVLLSCSVATAAAIVLMG
                     ISDGVHGLVLAAAALWGLGFGGAPTAFQAVTAVLAGPTADAAQSLTIAAWNGAVAGGAL
                     VGGLLLPLGTSSLPWCAAFLILVPLLFSRRVVLSAPADRCRSRR"
     gene            complement(15918..16880)
                     /locus_tag="BLU53_RS33195"
                     /old_locus_tag="SAMN04489733_6795"
     CDS             complement(15918..16880)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028566.1"
                     /locus_tag="BLU53_RS33195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6795"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_144024046.1"
                     /transl_table=11
                     /translation="MADFDRRTALKGGLTVSAVGLLGTATISAADAASGVAEPKIYGTA
                     AWNARPPGGAIEVQNHKPTYIVVHHTVEPGNVTDYTLEHAFWASRSIQNFHMDTRGWID
                     TGQQFTNSRGGHITEGRHRSLEILRGGTQHVLGANVGNNNSTCIGIENEGLYSKEDVTP
                     ALWDSLVKLVAYIASQYDISPEFIKGHRDFNSTECPGTVLYNRLPELRTEVGKLLGTAS
                     PKVDLPEWPLLKPGDSGPRVRTAQELLRARGFAVPVDGLFGQSTKDAVAAVAARNGLER
                     NTCGATAATDETGFLGSDVWPLIVGSGTDPRALKARLAG"
     misc_feature    16865..16879
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(16969..17844)
                     /locus_tag="BLU53_RS33200"
                     /old_locus_tag="SAMN04489733_6796"
     CDS             complement(16969..17844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165321.1"
                     /locus_tag="BLU53_RS33200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6796"
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="WP_063272658.1"
                     /transl_table=11
                     /translation="MGVDADVLTEWFDEVGRDLPWREPECSAWGVLVSEIMLQQTPVAR
                     VQPIWLEWMARWPVPSALAASSQGEVVRAWGKLGYPRRALRLHAAAAVIAAEHGDVVPS
                     DVDTLLALPGIGAYTARAVAAFAYGKRAPVVDTNVRRVVARAVHGAGDAGPPSNTRDMA
                     DVEALLPPEDAPAAKLSAALMELGALVCTARSPRCADCPIYEDCAWQHAGKPAYAGPAK
                     QVQKFAGTDRQVRGLLLDVLRGSEGPVEKARLDLVWHESGQRDRCLDSLLVDGLLEQTR
                     DGLFALPGEH"
     misc_feature    complement(17808..17823)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            complement(17976..18467)
                     /locus_tag="BLU53_RS33205"
                     /old_locus_tag="SAMN04489733_6797"
     CDS             complement(17976..18467)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466590.1"
                     /locus_tag="BLU53_RS33205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6797"
                     /product="carbonic anhydrase"
                     /protein_id="WP_063274694.1"
                     /transl_table=11
                     /translation="MTSIDVLLKRNQELGDVTPGDRSSPRPSLHVTILTCMDARIRVFE
                     IFGLIQGEAHILRNAGGVVTDDMIRSLALSQRKLGTREVLIVQHTDCGLSMVTEDDFKD
                     ELEAASGLRPTWSVEAFRVVEDSVRRSVQRVRRSDFLAHTDNVRGFVYDVKTGRLSEVA
                     "
     gene            complement(18519..19619)
                     /locus_tag="BLU53_RS33210"
                     /old_locus_tag="SAMN04489733_6798"
     CDS             complement(18519..19619)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441636.1"
                     /locus_tag="BLU53_RS33210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_6798"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_005165317.1"
                     /transl_table=11
                     /translation="MGRPIRTRRQATLASLAAELGVSRTTVSNAYNRPDQLSPELRRRV
                     LETARRLGYPGPDPVARSLRTRKAGAVGLLLTENLSYAFRDPAAVGVLEGLALACEDAG
                     VGLHLVPASPGREDVAAVHRAGVDGFVVYSVPDDDPHLGAVLERPVPTVIVDQPRVDGV
                     DRVGPDDAAAVTAMAEHLISLGHRQIGVLCMRLARERNDDFVSIQRQSAAHFHVQRIRL
                     EALAAAFSAAGVDWATVPVVERFDHTVDDGASAARQLLDAYPQVTAVICTSDILALGAL
                     AEAERRGLRVPQDLTVTGFDGITEAERSGLTTVHQPVLEKGKAAGKLLLSSADRVGPKV
                     ITLQTELRVGRTSAPPRTAEERWFGP"
     misc_feature    19591..19608
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(19755..19769)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    19756..19767
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    complement(19756..19771)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.05"
                     /tool="antismash"
     misc_feature    complement(19815..19829)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.96"
                     /tool="antismash"
ORIGIN
        1 gccgggcttg cccgcaccga gctgctgtcc tggatcttgc gggaactggc tccgtgaaga
       61 agggctcctc gcctggcaga ggcgaggagc ccttcccgcg cgttccccct gacccccgtc
      121 agacgcgctt ccggtaagcc cacgtggcga gcgggaagaa gaccgcgagc gcggccgcca
      181 tccagatcag cgagccggtc agcggaccgg cgatcggccc tccgttcatc agcccgcgca
      241 ggacgtcgga catctgcgtc accgggctga tgtcggccca cgccttcaac cagccgggca
      301 tggtgccggt cgggacgaag acgttgctgc cgaaggtcag cggcatcagc acgacgaaca
      361 tcaggccctg caccgcgccc gggctcttca ccagcatccc gacgaacacc gaggcccagc
      421 agaacgacag cgcgaacgcg atgacgagca ggatcgccag cgcgaactcg gccggtccgg
      481 tctggacgcg gtaacccatg atcgtcgcga cgaccatcaa cacgaccagg cacaccaggt
      541 accgcacgat atcggccagt acggcgccga tcagcggcgc ggaccgggcg atcggcatcg
      601 cgcggaaccg gtcgaacacg cccttggtga cgtcggtgtt cagctggacg ccgacggtca
      661 tgctggcctg caggatgttg aacaccatga tgccgggcac gatcatctgg agatagccct
      721 cggtgctgcc catgatcgcg ccaccgaaca ggtagacgaa catgaccagg aagatgatcg
      781 gcgcgatggt gacgtcggcc agctgctccg ggttcttgcg gatcttcagg atgccgcgcc
      841 aggcgaggga aagcccgtgc cgcgtgctgc tcgacagtga aacgcgccgt ggtgcgggcg
      901 cggcgatggt cgtcatacca ggctcccttc cggagtagtg tcctttgtgg actcgtcggt
      961 cttcttgccg gtcagcgcga ggaacacctc gtcgaggctg ggcagccgca gcgccagctc
     1021 gtccgcggtg atcccggctt cgtccagctt gcggaccaag gtggacagca ggaccgggtc
     1081 ggcgacgggc gcggtgagca gcccggtgtc gtcgtcccgg ttcggccggg ccccggtgag
     1141 cccggccagg atgcgctcga cggcgtcgag gtcggcgagc gcggacggcc gcacctgcag
     1201 tgtctggccg ccggtccgcc gcttgagctc gtcggcccgg ccgttcgcca cgacgtgccc
     1261 gtggtcgaac acggtgatcg tgtcggccag ctggtcggcc tcctccaggt actgcgtggt
     1321 gagcagcacc gtcgtgccgt cggcgaccag cgtccggacc acggcccaga cctcgttgcg
     1381 ggcgtgcggg tcgagccccg tggtcggctc gtccaggtac agcaccttgg gacggccgac
     1441 caggctcgcg gcgaggtcga gccgccgccg catcccgccc gagtaggtct tgatcgcgcg
     1501 gccggcggcg tcggtcagct cgaaccgctc cagcagttcg gccgcgcgct gcttcgcgtc
     1561 cgccctcgag aactccagca gcctgccgat caggacgagg ttctccgtac cggaaaggtc
     1621 ctcgtcgacc gacgcgtact gcccggtcag cccgatcatg ctccggaccg ccatcgggtt
     1681 cttgacgacg tcgtacccga agacgctcgc gtggccgcgg tccggccgga tcaaggtggc
     1741 caggatccgg acggcggtcg tcttccccgc gccgttcggc cccagcaccc cgaccacctt
     1801 gcccgccggg acctccagat cgaccccgtc gagcgccttc gtctccccat agtgtttgac
     1861 caggccctcg gccctgatcg cgtgagtcat cgctttcctc ctgtggatct cgccccgcgg
     1921 acaaaggtgc accccaggcc tggcagaccg cgcacagcgc gctgtcagcg gctgataagc
     1981 gctggtagac gccgtgtgag gaggttgtga aggtgttgtg gagaccgctg ccccggcgcg
     2041 cgtgatcggc atactcgacg gcatggtgat cgaagaacgt ccggttcgtc cggcggcgcg
     2101 tcccggcacc ggacggaagc tggtcagcgg gctcctcatc gcggcggtcg tgccgttcgc
     2161 ggtgctgacc gcgctgcggc tggtcggcta cgacggcaac acgtacacga tcgcggcgct
     2221 cgcgctcacc ccgtacgccg ggatcgcgac gttcgtgctc gccgtcctcg cgctggtcct
     2281 gcgccgctgg tggaccgcgg ccgtcgcgct ggtgctgacc tgcacgatcg cgtcgatggt
     2341 cctgccgcgc gcgttcgcga acgagcagaa ggcgctcgac gggaagcacg tccgcgtcct
     2401 ggcgtcgaac atgctcggcg gcggggcgga tccggccagg atcgtcggct acgtgaagga
     2461 acaccaggtc gacgtcctga gcctgaccga gctgaccccc gaggcgatca ccgcgctcga
     2521 ccgggcgggg ttgttccagg tcctgccgta ccgcgtgctg catccggccg agtgggcgtc
     2581 cggctccggg ctggtgtcga agtacccgct cacgccgttg aagctcagcg gcgactcgga
     2641 ctacaagcag cccagcgcga gcgtggatct cggggacggt gtccgcgtcg aggtcgtcgc
     2701 ggtccatcct tcggcgccga tgtgggaccg gtacgagtgg gtcgccgagg ccaaggacct
     2761 gccgtacgcc gacgcggagc acgacatccg gatcctggcg ggcgacttca acgcgagcct
     2821 cgaccacgcc ctctttcgcg agctgctgac caggggatac gtggacgcgg cggatgagct
     2881 ggggaaggcg ttgcagggga cctggacgaa cgggatcgcg ccgccggtgg cgatcgacca
     2941 cgtgctggcg gacaaacgga cggccatcgc ggacttcaag gtgctggaga cgccggggag
     3001 cgatcacgac gccgtctacg cggaaatcgt gctgcccgga aagtgacctt ccgccgtcag
     3061 gcttcccgct catgaggaag ctctggggaa ttccggcctt gtcgctgctc gcggcctgtg
     3121 tcccgggaca gctgcccgcg ggcgccccgg agagcgcgct cgggtgacgc gggcgcgacc
     3181 tggacggtgt cgccggttca ggtgcacctt gtggatgttc atggcacggt ccctcaccca
     3241 cgcggtgaag ggcgctttac ccgcgtcgca tgcggtgaaa gtccccttca tccaccccga
     3301 gaccggaagg caaggaccgg gcctagccga gcagggcgtc cagcgcttcg agcgtttcca
     3361 ggccgttggt cgcgagggag accccgcggc cgtgccggat cccgggttca cgcgggttga
     3421 tccgcacgag ggcaccggtc gcggcgctgg ccagctccga gtaccgccgc accgtcggca
     3481 cggcctgtcc ggcgccgagt tccaccacca cgaggtcgcg atgcgcgcgg cgccacgcgt
     3541 tcagctcgtc gagctgggcc tggctgcgct gcccgagcca gtcgtagtcg ccgaacatca
     3601 ggatgttggg cctggcgaga ccgccacaac gcgggcagga cggcaagggc gcctgcgcgc
     3661 gcatggtgtc ttcgtcgatc gggacctcga cgccgtccgc gggccagatc tccttggagc
     3721 acctgtcgag gcactgcagg tgatggatgg agccgtgcgc ctcggcgacc tgcggataac
     3781 ccgccttctg gaactgtccg tccacattgg acgtgaacgc ccgggtgccg ccaggtttgc
     3841 gcgctcccca ggacagcagg agccggaacc cgtcgtgcgg cacggtggcg cggtacagcg
     3901 cgagccggtg cccgtagaaa ccccaggcca gctcggaatc ttcggcgaaa tgccgagggt
     3961 cggcgagctc gacgaagctg atgcccagcc gctcgtacgg cggatacgcc ttccagaaac
     4021 cttcatcgcc ccggaaatcg ggcaggccgg agtcgacgcc catcccggcg ccggcgcaga
     4081 cgagcagcgc gccggcgccg tcgatcagtt ccgcggctcg ttcgagttca ctcacccggc
     4141 ttcgaagcct ggacgacctc gaattccagc aggttcgcac ccgtggagac cggcttcgcg
     4201 cgctcgcccg cgtgcgcctc acgcgccggg ccggacgccc acgcctggta cgcctcttcg
     4261 gactcccact tggtgtagac gaagtagcgc gactcgccgg agaccgggcg gagcagctcg
     4321 aagccgagga agccgggctg gtcgtcgacg gcgtgcagcc gcgcggcgaa ccgcttctcc
     4381 agctcggggc ctgcgccttc ggggacctcg atcgcgttga tcttcacgac agccatgccg
     4441 ccagcctacg acgaaatcgt tttgcgccgc gatgtgatgc gtgggacctt ccagacgatg
     4501 gctgacacca agatcctcat ctccggagcg agcgtcgccg ggctggcgct ggccttctgg
     4561 ctgacccggt acggcttcca ggtgaccgtc gtggagcgcg cgccgtcgtt gcgccccggc
     4621 ggccaggccg tcgacctgcg cggaacggcc aaggaggtcg cccgccggat ggggctcgac
     4681 gaacgcatcc gggcggcctg cacggacacg aagggcgaga ccctcgtcga ccggaagaac
     4741 cgcacgaagg ccaccatccg cgccgacgac ttcgacggcg acggcgtcgt cgcggagatc
     4801 gagatcctcc gcggcgacct gaccgaagtg ctctacgaag cgaccaggga gcggacggag
     4861 tacgtcttcg gcgaccggat caccgcgctg gacgagcggg ccgacggcgt cggcgtcacc
     4921 ttcgcgagtg gttcgagggc gacgttcgac ctggtcatcg gggcggacgg gctgcattcc
     4981 ggggtgcggg cgctggcctt cggcgaggag tcccggttcg tccggcatct gggttcgtac
     5041 ctggcgttct tcaccgtgcc gaaccggctc ggcctgcgga actgggccgt cggctacgac
     5101 gacgtcggcc ggtccgccgg gatccgcgcc gtccgcgacg gcgacgaggc gatggcgtac
     5161 ttcgggttcg cttcgccgaa gatcgactac gactatcgcg acgtcgaggc gcagaaggcg
     5221 ctggtccgcc ggttcgccgc cgggatggag tgggaggcgc cctggctgct cgaccggatg
     5281 gacgaggcgc ccgacttcta cttcgactcg tgcgcccaag tgatcatgga ctcctggtcg
     5341 cgcggccgtg tcgggctgct gggcgacgcc gctttctgcc cgtcgccgct ctccgggcag
     5401 ggcacgagcc tggcgttcgt cggcgcgtac gtgctcgccg gggaactcgc cgccggtctc
     5461 gacaccgggc tcaagcgcta cgaagccgtc atgcgcgagt tcgtcgagaa gacgcaagag
     5521 ctggggcggg agaacgcgga gtcgatcttc gcgaagtcgc ggacgggctt gcggatgcgg
     5581 tacctggcga tgcgggtcat gcggctgaag ccgttcgccg cgctggcctc gcggaagatg
     5641 cgggacgtcg tgaacggcat cgacctgccg gactacccgc gcgtttagag tcgtccgcag
     5701 gtgttgcgaa agccactttc gcaacgttga aggttgcgaa agtggctttc gcaacgcgcc
     5761 agtgcgtggg tgaggtgtca gccgcgcagg gtgcctggaa gcagttcggc gtccggcggg
     5821 atcgtcgtcc cgtggaacca cgcgtcgaag aacggccgca ggtcctgctc cgaaagcttg
     5881 atcgtgaacg cctcgaagtc cgcccaggtc gcgttggcgt tccggtacgc cgccggccat
     5941 tccttcagca gccgcgcgaa cgcgccttcg ccgatcttcc gccgcagcgc gtggacggca
     6001 aggatcccct tgtcgtagac gccgcggaat tcctgccccg cccccatgcc gaccagcttc
     6061 ggcttccaga aatcggtgct gccccgcatg atctccagcg cggcgcgata acggacgtcc
     6121 aggtcctcgt tgtcccgcga ctcctgccac agccattgcg cgtacgacgc gagacattcg
     6181 ttgaggcaga tgtccgacca cgaattcagc gtcaccgaat cgccgaacca ctggtgcgcg
     6241 gtttcgtgca ccacggtgat caggtcggcc catttcgcgt aggtcggcct ggtctgggtc
     6301 tccagtgaga agtggatgtc ctcgtcgaga tagataccgc ccgccgcgtc caccggatac
     6361 ggcccgaact tcgagctcag gaagccgatg atctccggca gccgcctgcc ggtgtcacgc
     6421 cggtcctcgg cgcccggcgc gtacgcgttg accaccggcg tcccgtccgg gagcgccatc
     6481 cggtcgacgg tgaacttgtc gatcgccacc gtggtcaggt acgccgcgac gggggtccgt
     6541 tcctgccagg acgtcgtcgt ccagccgttc gccgcggtct tctggatctc gcgcccgttc
     6601 gagatgacgg tccagccgtc cggcacgcgg gcggtgaggg tgaacatcgc cttgtcgcgc
     6661 ggggtctcgt tgacgggata ccagaacgac gccgaatgcg gctcgccgac gatgaacgcg
     6721 ccgccgtcct tcgacttctg ccagccgttc tcgctgccac ccgccttggg cgtcgccgac
     6781 ggatcgccgc catagaggac cttcgtgcgg aaggaggtgc cgttccggat cggctcggcg
     6841 ggcgtcacca ccagctcgaa ctcgccctcg cgcgtgaact tcgccggttt cccgtccact
     6901 tcaacggatt ggaccgtcaa gccgcgtaag tccaagttgt accgattgag gtcttgggtc
     6961 gctttcgcga tcaccgtggt gtcgccgtcg agacgcccct tcgcggggtc gtaagtgatc
     7021 ccgacctggt attcggccgc gtcgtagccg ccgttgccgt ccatggggta gtacgggtcg
     7081 cccgcgcccg gagcacccgg cgccgggttc atcggcggcg gcggaggggg cgtggccgga
     7141 gggggatcgg cactgcagcc gataatcagg gcgcagacga cccccaggac cagaccggcg
     7201 gcggggacac ggctgcacat ggaggggagc ttagtggtga ttcagcgcga cgggttggtc
     7261 actttcggcg gcgacgggcc gccgatcgtc cttctgcacg ggctgatggg cagggcgacg
     7321 acgtggtggc aggtcgcgcg aaggctcgaa ccgtacgggc gtgtccacgg cctcgacgcg
     7381 cgcgggcacg ggcgcggacc gcgcggcggg ccctggcgca ccgaacggtt cgccgacgac
     7441 gtcgccgagg tgctgcggac cttcggcgaa cccgcggtcc tgatcggaca ttcgatgggc
     7501 ggcctgcacg cgtgggtcac cgcggccaca catcccgagc tggtccgcgc cgtggtctgc
     7561 gaggacttcg cgccggatca gcgcggccgg acggtggaca cctggcgcgg gtacttcgag
     7621 tcgtggccgg tcccgttccg gtcgctggcc cacgtgcgcg aattcttcgg cgacaccggt
     7681 gactacttca tcgaatgcgt cgaggaacgc gaagacggct atcacctgat cgcgtcgctc
     7741 acggacctgt acgaaatcgc ggccgagtgg ggacggcgtg atttctggga gttcgtcgaa
     7801 cgcgtcaagt gtccgctgct cgcgatcgag ggcgaacgca ccgcgatgcc gcccggccag
     7861 caggccgaac tggccgcacg tgtgcccggc ggcctcggac ggcacatcgt cgtccaaggc
     7921 gccgggcacg tggtgcacga cgaagcgccg gagacctacc tcggtgccgt cgaagcgttt
     7981 ctctccgacg tcatcggtca gcccttcgcg agctgagcgt cgatccaggc gcgcaaccgc
     8041 gcttcgcccg ggtaaccgat gttccgcgac gacggcagtt cggcggcgtt gcggacaccg
     8101 accagcgtcg ggagatagcg gatgttgtac cgggtggaca gatcgcggct ctggtcgacg
     8161 tcgacctcgc ccagcaggaa ccgcccgccg tattcaccgg cgagccgctc gatcaccggc
     8221 ttcatctgac ggcacggcgg gcaccacgtc gcgccgaagt ccatgatgac cagcttctgc
     8281 ttcgagatgt tcatgacctc ggcgtagttg gccgaggtca ccgtcatcac gttctcggcc
     8341 gtcggtgcgg ccgaagccac gccgccgccg aatccggtga cgagtgccag cgcaccggcc
     8401 agcacgcaga cgaatcgttt gaccttggac aagacgatct cctttcagga cgaagaccag
     8461 gtcggaagat cgttcgcgac ccagtcttcg atgccttcgc ggtacttgcg gacgttcgtg
     8521 tacccgagct ccagcaggcg ccgtccgacg aattcgctgt tacggcacgg cgtgttcgcg
     8581 caatagacga cgatcgcggc gcccttgtcc ggaagcaccg ttggtgccag ccggtcggtg
     8641 aattcggcgg cctgctcgta cgggaaaccc ggaatgttgc gcgcttccgg cagatgctcc
     8701 ttttcgaaat aggcgaccgg catcgtgtcg accacgacca ccgagccgga ctccatccgg
     8761 gaaagcagtt ccgtacgggt gatcaacggc agcatggtgc cccttctttc ggcgaccgtg
     8821 attgacgatt cacatcgtcg gccgcctcgc gggacacgct ctagtgccgc ctcggcatgc
     8881 cgaggggtta tccggcggcc acccggccgt ggcggtgcag ccaggaacgg tacgacgccg
     8941 tccgttcggc gagccgccaa tagcccgccc tcgcctcggt ggcgagttcc gggacaccgc
     9001 gtgcgcacgg accgtcttcc cgccacgcga gcacatgccg cacgcacatc ggcgcgcccg
     9061 ccagcggccg gatggccagc ccgtccgccg gtggccgggt cggctggacc agcccgaccc
     9121 cgtatccgcc gctgaccagg tcttcccgcg cggtgtcgat gtcgacgtcg tgggtgatcc
     9181 gcggatcgaa accgtgcgcg agacacattt cgcggaacac cacccggcag ccatcaccgc
     9241 cgctcgacac gatccagtcc tccccggcga gttcggcgag ctcgatctcc tcttcgccgg
     9301 cgagcggatg ttccgcgggg atggcgacga aagacggctc ctcgaccagc gtcagcgtcc
     9361 gcacttccgg cggcaccgga agaccacgac ggccgcagat catgatcagc gcgaggtcga
     9421 tgccccggtt cgcgacctgc gccagcagcc gcgtgcgcga agtgtcggcg cgcgtgcgga
     9481 acggctcgcc ggggcgcagg tcgcgcagac cgccgagcag cgaacccgtg atggcgctgt
     9541 cgttccagcc gatccggatc gattcgccgg tctcgggttc ccggcggtgg aagtcgtgct
     9601 ccagttcgtc gaaggtgagc acgatcgcgc gtgcccgccg caggatcagg gcgccgagtt
     9661 cggtgggccg caccccgtgc tggtcgcggt ggaacagcgg gccgccgacc atccgctcga
     9721 tccggcgcaa ctggtggctg agcgccggtt gcccgagccc cagcccggcc gcggcacgat
     9781 tgagactgcc ggcggcggcg atcgcacaga tcacgcgaag atgccgaacc tgaatctcca
     9841 tgacttcgta taccgcgacc ggttcgcgcc cggcaccccc gaaagtagag acagccgatt
     9901 tctcataacc cggtgacaac attcgacggc aatacccgcg cgggcgtgcc gtggctacgt
     9961 tcggtcgacg ccccgcagat cacgcgaatc aggagccgtc ttgccgcgac cactgccact
    10021 cacggagcat tgcgccgatc cgctggcgcg ggccgagcac gtttgtctcg gcgtcagccc
    10081 gttcaacagc catttcaccg tggaccgtat cgccgatctc gcccgctggg ccatgtcggc
    10141 ctttcgggaa ttccatttct tcgtcccgga cggcccgtcc gcgttcaccc tcgaagcgct
    10201 cggctacgac ccggtccgcg ccgcccaaaa ggcgcaacga caggggaatt acacgcgtaa
    10261 caagatcgtc cgggcactgc agcgggtctg tccttcggat ccgcacacct tgatactgga
    10321 cgcctcggtg ctggaggccg acagcgcgta tctcggcctg ctttccgagg cacaccagcg
    10381 gttcgccacc gatccggagt tcgccgagca gtgcctcggc gccacgggct gggtgctgga
    10441 ccggcgcctg cccgaaggcg aacaccccac tcgtgaccag ctgcgcagcg cggtccggta
    10501 cttcctcgcc gagttgccga tgttcgtcgg caccgtcgcc gtggccggcg tcgaaagctc
    10561 cgtgttcgcc tatcaccagc gggtcggctt cctcgaacgg ctctaccgcg gcgaactctc
    10621 gtggcggccg ttgccgggcc aaggattcgt catcctcgaa caagccgtcc cggaaccggt
    10681 ggagtgagcg tggaacacga cgacttctcc ctgcgccggg tgccggccga ccgccgctac
    10741 tcctgggttt ccgtcgcact gcaacggttc gggcaggttt cctcgttcca tcagttcctg
    10801 ctcggcgcgg tgctgggctt cgggatgacc ttctgggacg cggtactcgc catcacgatc
    10861 ggttccgtac tgctggagat catcaccatc ctgatgggga tcgccggcac gcgggaaggg
    10921 ctttcgacgt cggtgctcgc gcgctggacc ggcttcggca ccggcggatc gtcgctggtg
    10981 gggctcctga tgacggtgag cctggccggc tggttcgggg tgcagaacga cgtcttcgcc
    11041 cacggcctgc acgcgttgat gggcggcccg ccggtgtggg tgtgggcgct cgcgggcggt
    11101 gcgctggtca ccgcgatcgt cgtgttcggc ttccacgcga tggcctggac ggcgtatctg
    11161 acggtgcccg ctttcctggc gctggcgggg ttttcgatca tctcggcgct cggcgaccat
    11221 tcgctgccgg tgctgatgtc cgggccgccg ccgggcccgg cgatgtcgct ggcgcagggc
    11281 accacactgg tggccggcgc cttcatcatg ggcgcgatca tgacgccgga catgacccgg
    11341 ttcaaccgca ccgcgtccga cgtggtgaag cagaccctgg tcagcgtcac cctcggccag
    11401 tacctgatcg gcctgatcgg ggtactgctc gcacacgcgg cgaaaagcgc cgacgtggtc
    11461 gggatcatca cctcgtcgtc cggggtgctc ggcacgctga tcctggtcac cgcgatcctg
    11521 aagatcaacg actggaacct ctattcgtcc tcgctcgggc tggtgaacgc cgtgcaggtg
    11581 ctgctgtccc ggcggctgga ccgcaccacc gcgaccctgc tgctcggcgg cctcggcacg
    11641 gtgctgtccg cgatcggcat cctcgaccac ttcaccacct tcctgacctg ggtcggcgtg
    11701 ctcacgccgc cggtggccgg ggtggtgatc gccgagtact acgtggtccg gcgctggaaa
    11761 ccggagctgg aggccggccg cgcgtcgggg gaactgccgt ccacctgccc gtcctgggtg
    11821 cccgccgcgc tgatctgctg ggcggccgga gcggcggtgg ggatctggct gccgtggggg
    11881 atccccacgg tgaactccgt tttcggcgca tttctgctgt atgttcttct cggcagacgg
    11941 accacggccg cggcggctcc cgcggccacg acttcttccg gcgggtcgaa aacccgttcg
    12001 tgacaaagga gttcgacgtc gtacagctgg atgtccacca cctgcgggtg atccgggcga
    12061 tcgcggacac gggcagcctt tcccgtgccg cgatcgcgct gggcgtcacc cagcccgcgg
    12121 tttccgcgca actcaaacgg ctggagaaca tgctgggcta ccagctgttc gatcggtgcg
    12181 aaggcggcgt gaccccgacc ccgatggggg agctgctgtt gcgccgcacc gccgctttgc
    12241 tgccacagct ggacaagctg ctcgaagaca tcgagcagcg cgtctgcccc agcggcccgc
    12301 ccgccgtcgt ccgggtggcc gcggtggcca gcgcgctggt ggcgtgcctg ccgtcgctgg
    12361 tgaccaggtt gtggccggag gtctccgagg tgcaggtcgt gcacgacgac catcccgagc
    12421 ggctgttgcc actgctggcc cagcgccgcg cggaattggc gctggtcaag gactatccgg
    12481 gctacgagct cgaaatcccc gcgaacgtgg acaccgcggt ggtggtgacc gagccgacct
    12541 tcgtcctgct gcccgcctcc catccgttgg cgcgggagaa ggtcgtcgac ctgcgcgacc
    12601 tgcgggacga atcgtgggtg atggtgtcgg attcatcggc ggccacgttc accaagtact
    12661 tcgccgacac ctgcgcgcgg cacggtttca cgccgacgtt cacccatcag gtgacttcgc
    12721 agcaggtggc gctgctggtg gtcaaggcgg gtgcgatcgg gctgtcccag ccgatctgcg
    12781 atccgggaga ccacggcatc gtgacccggc cgctgcgcgg ggacgtgttg ccgcgcaggc
    12841 atgttctcgc ttggaacaag gagacgttcg tggcggggcg gcgggacgag ctgctctccg
    12901 cggtggtcga cgcttactgg gccgaggcgc gaacggcacc cgtctatgcc gagtacctgg
    12961 acagacctcg tgagtggtga ggcaaaggtg acgtgtggtg cgcggtccac cgtccacaag
    13021 ggacatcaag gggtcaccgc gggtgggtga ccgggggtga aggctccctt caccggatta
    13081 gacgcggcga agggagcctt cgccccaccg ccgaccccgc ccgcgagcac gacccctcaa
    13141 gagaaccacc ggcgatgtgg tggtgaaagc cactttcgca acccaccgtc ctcaccgctc
    13201 acgaggtaac ttcagctccc gggaaagagc agcgagtccg gcggccgcac cgtgccgtcc
    13261 agccaggcgt gggtgaactc gccgagatcg cgttgcgtca tcgcggagac gtagagctcg
    13321 aagtcgtgcc agttctggtt tccctgcggg ttgatcaccg gaaagcccgc caggatctgg
    13381 aagaacgcgt cgtctccgac gagacggcgc agcgcgtgca ccatcagcac cgctttggcc
    13441 gtcggcgcga attcggtgcc cttgccggga tcggtgagct tcggcgccca gaaagccgcg
    13501 tcgtcgcgca ccttcgccac catttcgcgg tagcgccggt ccggatcgac gccgttcttc
    13561 tcgtcccaca gccacaccgc gtaccgcgcg atggactcgg gcatcagcgc gtcgcgccac
    13621 atcttgccgc tcacgccggc tccccaccat tggtacgcgc tggcgtacac cagatcggcg
    13681 atcgtggcgg tgcgcccgta caccggtctg gtctgggcgc cgtgcgtgta gccgagggag
    13741 cggtcgagga acagcccgcc cgccgccgac tgcgggtagt cgccgaactt cccggtgagg
    13801 aattccagca cctcgggcag ccgcccgccg atcttccgtt tgtccacggc gcacgggtgg
    13861 taggcgttga tcgcggtccg cccgccggga agggtgatcc tctcgacctc ccagcggccg
    13921 atgccgagca tcgccgtgct cggcgcgagg gcggtctcct ccgaccaggt gacggtgtgc
    13981 cgcccgacgc ccgcgggcac gtccgagacc tgggaaccgt tgcccagcac ggagaattcg
    14041 tccaatacgg tgacggagac gcgcagggtc gctttgtcga cctcggtgcc gttgacgggg
    14101 aaccaggtca tcgccgaacg cggctgcccg gtggcgacgg cggaatcgcc gtacgcggcc
    14161 agccagccga cgcgtccccg cgccgtgggg atcggttccg gacgcccgtc gtaaccgacc
    14221 accacggtga accgcgcacc gttggcgagc ggggtgcgag gcgtgatcac cagctcgtgt
    14281 tcgccctccc tgcggaacgc cgcggccacg ccgtcgacgg tgaccgaccg gacggtgaga
    14341 ccacgcagat cgaggtcgaa ccggtccagg tcctgtgtcg cggtcgcggt gatggtcgcc
    14401 ttgccgctca agaacatcga gtacggcgcg tagtccagcg cgagtgaata ccgatcgacg
    14461 tcgtagccgc cgttgccgtc cttcgggtag taaggatcgg gtccgaggac ggtgccgtcg
    14521 ggtgagacgt gcacgtatcc gtcgctgccg ggtgccggct ttgccaccgc cgaagccggg
    14581 caggcgccga gcatcgtggt ggcgagcaac gcggtgcaca gtggctcctg ccatcgaatc
    14641 cgcacggtca tgaacgagcc ttctctctga acggggagga tgcccggcca tcgtgcgtac
    14701 gctcgcgccg cgagcggcac tgccagccgc tcatgccgcc gggttatccc ggccgataac
    14761 cgcgcggcat acccgccagg gactacccgc gtcccccggc ggaagagatc gtcggagcat
    14821 gctgcccctc ccggcgctgc tcgcgctgac gaccacggtg ttcctcggct gcctcaccga
    14881 agtgctgccc gccgggctgc tgctgggcat gtccgaggag ctgggcgttt cgccgtcggc
    14941 caccgggcag ctggtgaccg tctacgcgat cacgaccgcg ctcaccgccg tcccgctcac
    15001 cggcgcgacc ctccgggtgc cgcgcaaacg cctgctgctg gtgctgatct tcggcttcct
    15061 ggcgaccaat ctggtgatcg ccgtgtcctc gtcgtacccg ctgatcctgg ccacacgggt
    15121 cgtttccggc gcgctgaccg gggttatgtg gtcgctcgtc gcgggttacg cgatgcggct
    15181 cgccccagcg ggactcaccg ggcgggcgct ggccgtggcc atgtccggca caccgatcgg
    15241 cttcgcgctg ggtgtgcccg ccggtaccgc gctcggtgaa ttcgccgact ggcgctgggc
    15301 gttcgccgcg atggcgctga tctccgtgcc gttgctggcg tgggtgtccg tcgcggtgcc
    15361 cgccgtaccc gcggaacgga cggaaccgac ccggccgctg gccgcgtcga ggctgccggg
    15421 aatgcgcccc gtactggcga cggtggcgct gttctccttg gggcacaacg tggcctacac
    15481 ctacatcggc ccggtgttcg ccgggctggg cgtggagcga atgctgggcg ccgcgctgct
    15541 ggtgttcggc tgcgccacgg tgggcggact ggtcgccgtc ggctccgcgc tcgacagccg
    15601 tccgcgcgcc gtgctcctgt cgtgctccgt cgcgaccgcc gccgccatcg tcctgatggg
    15661 gatcagcgac ggcgtccacg gactggtgct ggccgccgcg gccttgtggg gcctgggatt
    15721 cggcggcgcg ccgaccgcgt tccaggccgt caccgcggtg ctcgcgggcc ccacggccga
    15781 cgccgcccag tcgctcacga tcgcggcctg gaacggcgcc gtcgccgggg gagccctcgt
    15841 cggcgggctg ctgctgccgc tgggaacgtc gtcgctcccg tggtgcgcgg ccttcctgat
    15901 cctcgtgccg ctgctgttca gccggcgagt cgtgctttca gcgcccgcgg atcggtgccg
    15961 gagccgacga tgagcggcca gacgtcggag ccgaggaatc cggtctcgtc ggtcgccgcc
    16021 gtcgcaccgc aggtgttgcg ttccagcccg ttccgggccg ccaccgcggc gaccgcgtcc
    16081 tttgtggact gtccgaacag gccgtcgacc gggacggcga aaccgcgtgc cctcaggagt
    16141 tcctgcgccg tccgcacgcg aggcccggag tcaccgggtt tgagcagcgg ccactccggc
    16201 aggtccacct tgggcgacgc ggtgcccagc agcttcccga cctccgtgcg cagctcggga
    16261 agccggttgt acagcaccgt tcccgggcac tcggtcgagt tgaagtcccg gtgccccttg
    16321 atgaactcgg gcgagatgtc gtattgcgac gcgatgtacg cgaccagctt caccagcgag
    16381 tcccagagcg cgggcgtgac gtcctctttg ctgtagaggc cctcgttctc gatcccgata
    16441 caggtgctgt tgttgttgcc cacgttcgcg cccagcacgt gctgggtccc gccgcggagg
    16501 atctccaggc tgcggtgccg tccttcggtg atgtggccac cgcggctgtt cgtgaactgc
    16561 tggccggtgt cgatccagcc acgggtgtcc atgtggaaat tctggatcga acgcgacgcc
    16621 cagaaggcgt gttcgagcgt gtagtcggtg acgttcccgg gctcgaccgt gtggtgcacg
    16681 acgatgtacg tcggtttgtg gttctgcacc tcgatcgccc cgcccggcgg ccgcgcgttc
    16741 cacgcggccg ttccgtagat cttcggttcc gccaccccgg acgccgcatc ggcggcggaa
    16801 atcgtcgctg tccccagtag cccgacggcg cttaccgtca ggccgccctt gagcgcggta
    16861 cgtcggtcga agtcggccac gggcgtaact cccatcatgc gcgttggccg gaaaactaac
    16921 ccgccatcgc gccgatgaca accattgacc aacttttgtc gtaatgcgtt agtgttcgcc
    16981 agggagggcg aacaggccgt cccgggtctg ttcgaggagg ccgtcgacga gcagggagtc
    17041 gaggcaccgg tcgcgctgcc cggattcgtg ccacacgaga tcgagccgcg ccttctcgac
    17101 cgggccttcg ctgccgcgca ggacgtcgag cagcaaaccg cgcacctggc ggtcggtgcc
    17161 ggcgaacttc tgtacctgct tcgcgggtcc ggcgtaagcg ggtttgcccg cgtgctgcca
    17221 agcgcagtct tcgtagatcg ggcagtccgc gcagcgcggc gagcgcgccg tgcagacgag
    17281 cgcgccgagt tccatcagtg ccgcggagag tttcgccgcg ggcgcgtcct ccggcgggag
    17341 cagcgcctcg acgtcggcca tgtcgcgggt gttcgacggc ggcccggcgt cacccgcgcc
    17401 gtgcaccgcc ctggcgacca cgcgccggac gttcgtgtcc accaccggcg cccgcttgcc
    17461 gtaggcgaag gccgcgaccg cgcgggcggt gtacgcgccg atccccggca acgcgagcag
    17521 agtgtccaca tcggacggaa cgacgtcgcc gtgttcggcg gcgatgacgg ccgccgcggc
    17581 gtgcagccgc agcgcgcgcc gcgggtagcc gagtttgccc caggcgcgca cgacctcgcc
    17641 ctgcgacgac gccgccagcg ccgacggcac cggccagcgc gccatccatt cgagccagat
    17701 cggctggacg cgcgcgaccg gggtctgctg caacatgatc tcgctgacga gcacgcccca
    17761 ggcggagcat tccggctcac gccagggcag gtcgcgcccc acttcgtcga accactcggt
    17821 cagcacatcc gcgtcgacgc ccaccgggcc agcttaaaga gtgcgcccgc gcgtcgaacg
    17881 tgggcccagg gcgtagctga aggggacttt cccctcgtct cacgcggtga agggcgcctt
    17941 ccccgcatcg catgcgggga aagtcccctt cagctctacg cgacctcaga caaccgcccc
    18001 gtcttcacgt cgtagacgaa gccgcgcacg ttgtcggtat gcgcaaggaa gtcgctgcgc
    18061 cgcacacgct gcaccgaccg gcgcacactg tcctccacca cccggaacgc ctcgaccgac
    18121 cacgtcgggc gcagcccgct ggcggcttcg agctcgtcct tgaagtcgtc ttcggtgacc
    18181 atggacaggc cgcagtcggt gtgctgcacg atcagcacct cacgcgtgcc gagcttccgc
    18241 tggctgagtg cgagcgagcg gatcatgtcg tcggtgacga cgccgcccgc gttgcgcagg
    18301 atatgcgcct caccctggat caggccgaag atctcgaaca cccggatacg ggcgtccatg
    18361 caggtcagga tcgtcacgtg cagcgatggc ctcggagacg agcggtcacc aggagtgaca
    18421 tcacccagct cctggttccg cttgagcagt acgtcgattg aggtcacgtg ttcattggaa
    18481 ccgacgagcc gggcgacggc aacgcgggtg gacgcggatc acggcccgaa ccagcgttct
    18541 tcggccgtcc gcggcggcgc ggacgtgcgc ccgacgcgga gttccgtctg cagggtgatc
    18601 accttcggcc cgacccggtc ggcggagctg agcagcagct tgcccgccgc cttgcccttt
    18661 tcgagcaccg gctggtggac ggtggtgagc ccggaacgct cggcctcggt gatgccgtcg
    18721 aacccggtga ccgtcagatc ctgcggcacc cgcagcccgc ggcgctccgc ctcggccagc
    18781 gcgccgaggg cgaggatgtc cgaggtgcag atcacggccg tgacctgcgg atacgcgtcg
    18841 agcagctggc gcgcggccga cgcgccgtcg tccacggtgt ggtcgaagcg ctcgaccacc
    18901 ggcacggtcg cccagtcgac cccggccgcc gagaacgcgg cggcaagcgc ctccagccgg
    18961 atccgctgga cgtggaagtg ggcggcgctc tgccgctgga tggagacgaa gtcgtcgttg
    19021 cgctcgcggg ccagccgcat gcacagcacg ccgatctgcc ggtgacccag cgagatgagg
    19081 tgctcggcca tggcggtgac cgcggccgcg tcgtccgggc cgacccggtc gacgccgtcc
    19141 acgcgcggct ggtcgacgat caccgtcggc accgggcgct ccagcacggc gcccagatgc
    19201 gggtcgtcgt cgggcaccga gtagacgacg aagccgtcga cgccggcgcg gtgtacggcc
    19261 gcgacgtcct cccggcccgg gctcgccggg accaggtgga ggccgacgcc cgcgtcctcg
    19321 caggccagcg cgagcccttc gagcacgccg acggcggcgg ggtcgcggaa ggcgtaggag
    19381 aggttctcgg tgagcaaaag accgacagcg ccggctttgc gcgtccgcag tgaacgggcc
    19441 accgggtccg ggcccgggta gccgaggcgg cgcgcggtct cgaggacgcg gcggcgcagc
    19501 tcaggcgaca gctggtcggg tcggttgtag gcgttcgaga cggtggtcct cgacacaccg
    19561 agctctgcgg ccaacgacgc cagtgtcgcc tgcctcctgg tgcggatagg acggcccatc
    19621 cgcaaaccgt aacggttcag aacgttttgc agaagcatca cccgacgtgt ggcaggtctc
    19681 gattcagagt gaccctgggt acagctcgtg cctggacggg gagcgcggtc atccggatgg
    19741 ggtacagttg aatctgacaa cggtttccat tacccggcat tggggacacc tggcctgggc
    19801 atccgcagga gtgcagtaaa tgaattcccg ccgtactaag agtgttttcg cggccgtgtc
    19861 ggccctggcc gtcctcgcgc tcggcgcgac ggcttgcgcg tcgagcgaca aggcgtcgac
    19921 gggctccggt tcgccgaacg cgtccgccgc gaacccgggt ggtggcgaga agatcaaggt
    19981 cgtcgcctcg accgacgtct ggggcagcgt cgtgaccgcc gtcggcggcg acaaggtcga
    20041 ggtcacctcg atcatccacg acccctcggc cgacccgcac tcctacgaga ccaccgcgag
    20101 cgacgccatc gccgcgaaga acgcgaagct gacgctgtcc aacggcggcg gctacgacga
    20161 gttcttctcg aagctcgccg accaggccac cggcgcgcag aagctggtcg ccgtcgacat
    20221 cgccgcgacc ggcaacgaga acgagcacgt ctggtacagc ctccccggcg tcgagaagat
    20281 cgccgaccag gtcgccgcga agctcggtga gatccagccc gcctcgaagg acgccttcac
    20341 cgccaacgcg accgcgttca agggcaagac ccaggaactg ctgaagaagg tttcgggcct
    20401 gggcgcttcg aacgcgaagg tcgtcgccac cgagccggtc gcgcactacc tgctcgacag
    20461 cgcgaaggtc accgacgcga cgccgcccgc cttcgccgag gccgtggaag cggagcagga
    20521 cgtgcccgcc gccgcgctca acgaggtcaa gcagctgatc tccggcaagc agatcaaggc
    20581 cctgatcaac aacgcgcaga ccaccacccc ggtcacccag caggtcgtcg gcgacgccaa
    20641 gaccgccggc atcgcggtcg tcgacgtcac cgaaacgctc ccgcagg
//
