LOCUS       NZ_LT629789            22541 bp    DNA     circular CON 13-MAY-2024
DEFINITION  Amycolatopsis keratiniphila strain FH 1893 chromosome I.
ACCESSION   NZ_LT629789
VERSION     NZ_LT629789.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900105855.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 02:01:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,886
            CDSs (total)                      :: 8,813
            Genes (coding)                    :: 8,742
            CDSs (with protein)               :: 8,742
            Genes (RNA)                       :: 73
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 26 of 71
            Pseudo Genes (incomplete)         :: 51 of 71
            Pseudo Genes (internal stop)      :: 1 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:07:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6051550
            Orig. end                         :: 6074091
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT629789.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22541
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="25"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22541
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22541
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12541](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12541)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(54..926)
                     /locus_tag="BLU53_RS27275"
                     /old_locus_tag="SAMN04489733_5585"
     CDS             complement(54..926)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330834.1"
                     /locus_tag="BLU53_RS27275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5585"
                     /product="ATP-NAD kinase"
                     /protein_id="WP_072029096.1"
                     /transl_table=11
                     /translation="MGEAVAGIVANPASERDIQGLRSALRVAGVGRVMVWADAGKIIGT
                     VRRMVDAGASVLICLGNESMMRAAAAACGDVPLLMLPAGGADESTVAGLAAGLVATHQV
                     DTDLVTNRATVLEVVTKARREIALTDVSVCSESRWDPASLTELYCTFAVPDGVGLSSIP
                     GRLCPSPKSTVDGVAVSLGPVDETPYVVQAPIAPGEVREVGVRGWSVLHAGVRVDLAAG
                     GGSIALDGQPHFVLKPGESAFVELKPDGPWCVDVRAVMAEATRTGLLLGRKPTAALPTP
                     RLADAPFPG"
     gene            complement(1005..1715)
                     /locus_tag="BLU53_RS27280"
                     /old_locus_tag="SAMN04489733_5586"
     CDS             complement(1005..1715)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005459374.1"
                     /locus_tag="BLU53_RS27280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5586"
                     /product="hypothetical protein"
                     /protein_id="WP_072029097.1"
                     /transl_table=11
                     /translation="MNGETGRWIGGVALILAPLVWFAGLLLRHLVLKDFTPEQVAWFDE
                     QPFAAPGQLAAYAANPGLVTAAYSVFLLGAILLLPAFLMLAKIVAEKAPALAGWGFLLL
                     ALGLFARVYFAGVDLAAFELVDKLGLEQATRLVMDDYVDLSYGLWRIPVTASVGQYAGG
                     LLLAIGAFRAGTFGTGRALLFLWPCTLWMGVLKESEFLSVVTAVALGLALVPLGVRVLT
                     GRRPVDQKSRALSW"
     gene            complement(1857..2060)
                     /locus_tag="BLU53_RS27285"
                     /old_locus_tag="SAMN04489733_5587"
     CDS             complement(1857..2060)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222289.1"
                     /locus_tag="BLU53_RS27285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5587"
                     /product="cold-shock protein"
                     /protein_id="WP_005163378.1"
                     /transl_table=11
                     /translation="MTQGTVKWFNSEKGFGFITPDNGGGDVFVHYSEIKGNGFRTLEEN
                     ARVEFEIGQGAKGPQATSVTVI"
     misc_feature    complement(2115..2130)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.51"
                     /tool="antismash"
     gene            complement(2325..2495)
                     /locus_tag="BLU53_RS45170"
                     /old_locus_tag="SAMN04489733_5588"
     CDS             complement(2325..2495)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005163371.1"
                     /locus_tag="BLU53_RS45170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5588"
                     /product="hypothetical protein"
                     /protein_id="WP_170064563.1"
                     /transl_table=11
                     /translation="MADEAKPQDKSVSGVVPVLFSADAETHDIAVVATNREALRRSPFG
                     TEVPLRAASGE"
     gene            complement(2756..4417)
                     /locus_tag="BLU53_RS27290"
                     /old_locus_tag="SAMN04489733_5589"
     CDS             complement(2756..4417)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009071745.1"
                     /locus_tag="BLU53_RS27290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5589"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_267284133.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.9e-37, bitscore:
                     125.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.6e-34, bitscore:
                     117.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYQPGASVAQTAVRILTEAQIHRVYAVVGESFLDLLDALQRERS
                     ITFVSARHDSGAAFMAEAEGKLTEHPAVLLAGRGPSAANLAIGVSTAYQDESPMVVLLE
                     NPPQDPGPTSELPTADLTAMFEPISKWTGRAESPDEVPGLLVEALTRCREGRPGPTVVA
                     VPADFWGVPFDSAKPVAAVRPPATGALGRTAEAVAQLVDEARYPVVIVGGRARAARDEL
                     IAVADELALPVYNAFRRQDAFPENHARYAGHLGIGIPARQLDALERADLVLALGTQLDE
                     VTTQSFRYPTPSQTLVLVGTGIEPARRGGLTFRVDSEVEPFLRELRNVASPRQRRASAA
                     NAAVHTFMTPPDTSGATRVHPADVIRAVRKLAPEDAIVTSDAGNFAQFMHRYWCFTAPR
                     SQLGPSNAAMGYAVPAAVAAKLAEPRRTVIAMAGDGGALMTGQEIETAVRYRVPVTVLV
                     FQNGVHGPLAVHQARKHGRLSGVTVPITDFASWARGLGAAGYTVDDREELEPIIASALV
                     RQRPCVIDIRTDPDVVTPDIRLTSLLGAARPQQGGQ"
     misc_feature    complement(4406..4422)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    4559..4570
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.05"
                     /tool="antismash"
     gene            4589..5821
                     /locus_tag="BLU53_RS27295"
                     /old_locus_tag="SAMN04489733_5590"
     CDS             4589..5821
                     /EC_number="1.1.99.24"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0047988 - hydroxyacid-oxoacid
                     transhydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642937.1"
                     /locus_tag="BLU53_RS27295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5590"
                     /product="hydroxyacid-oxoacid transhydrogenase"
                     /protein_id="WP_063275109.1"
                     /sec_met_domain="Fe-ADH (E-value: 6.7e-103, bitscore:
                     343.3, seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYGTGSSDEIGYDLTQYGARRVLVLTDPGVAATGWPQRIAEGIE
                     TYGIEAVVFDGVHVEPTDVSMRKAVDFARGQGEWDAFVAVGGGSAIDTAKAVNLLTSND
                     GDLMDYVNAPVGGGRAPSSPLKPLVAVPTTTGTGSESTTVCVLDVLSLRVKSGISHLRM
                     RPSLAVVDPRLTVSQPPEVTAASGMDILCHAAESYTAKPYTEFDRKRPEDRVPYCGSNP
                     LADMFAEQSLRLLSWALPAAVRDGSDMKAREAMALAATFAGLGFGNAGVHIPHANAYPI
                     AGQVREFHPPGYPGDEAMVPHGMAVSLTAPAAFRFTFDAAPDRHIRVARLLAPDYEWPG
                     DLRDHLPAVLGQIMREIGIPNGIGAVGYTESDVDSLVSGTVKQQRLLATAPREASEADL
                     AVILRESVTLW"
     gene            5815..6234
                     /locus_tag="BLU53_RS27300"
                     /old_locus_tag="SAMN04489733_5591"
     CDS             5815..6234
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330831.1"
                     /locus_tag="BLU53_RS27300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5591"
                     /product="thioesterase family protein"
                     /protein_id="WP_016330831.1"
                     /sec_met_domain="4HBT_2 (E-value: 2.4e-15, bitscore: 56.0,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNAEYPHWQTVPLRWKDNDVYGHVNNVVHYSVMDTVINTWLIER
                     GGLDIETGAVIGLCVESQCKYHASVSFPGELEVGLRVGHLGRSSVRYEVGMYSKETVIA
                     EGHFVHVFVDRESRRPVPVEGLLRSALEELRTGLG"
     gene            complement(6190..7926)
                     /locus_tag="BLU53_RS27305"
                     /old_locus_tag="SAMN04489733_5592"
     CDS             complement(6190..7926)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030767.1"
                     /locus_tag="BLU53_RS27305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5592"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_072029098.1"
                     /transl_table=11
                     /translation="MSVWGLYRSALAGQWRGGLVLLACSVLESAPAFLSGRLVELAVDE
                     GFAADRPGTGLRWLAVFGLVAVIGAFGSRLVWHQLGKVVEPLRDALVTAVVRGVLHDPA
                     PPRNQPDASGVARITQHVEVVRDATAGLLVQARGMIVTTVAALAGLFTVAGSLALIVAI
                     PVVVSVLVFACLLPSLARRQRALALADERTAEVAGASLSGMRDIVACGAEPLAALELYD
                     AIDTQAKAAVRVARSGAARTVVIATGGFVPLLLALLVAPGMVQAGVLTAGAALGALVYL
                     ATTMQPALRGLAATASTVVLRLIVALRRLAETAEGEPEADGTAEPDGTAIYVRDLTFSW
                     GAAAQPVVRGLDLHLRPGERLAVVGPSGIGKSTLAGLLTGMLAPQAGRVLLGGVPVREV
                     PAALRHRMVALIPQEAYVFAGTVRDNVGLFAQTAMDGELLAAVRAVGAEPLVTRLGGLD
                     GEIGHGTLSAGEAQLIALARVYASGATVVILDEATSHLDPPAEARAERAFAERGGVLVV
                     IAHRLTSALRADRVLVMDGKETALGTHLELMDRSTRYAQLMHAWSPRLPQPSAQFFQRA
                     PE"
     gene            complement(7923..9590)
                     /locus_tag="BLU53_RS27310"
                     /old_locus_tag="SAMN04489733_5593"
     CDS             complement(7923..9590)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020633046.1"
                     /locus_tag="BLU53_RS27310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5593"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_072029099.1"
                     /transl_table=11
                     /translation="MAGSADRLLVKVTALDRPRLIALILSALAGTAAGLLLPGALAAAV
                     DAVVAGRPSLPEVTWLIVLGVTEIAVGLIGGILTARMTASATAWLRRELADRYLALGTR
                     STFADGDAISRLTGDCTGAGLVASVVVQLGSTTLISGGAVVLLALMDWRLALVFLGSIP
                     FGLMLARTHLKNTADDVLTYQEVSGELAARMVDAVAGLRTIAASGTADREADRVLRPLP
                     KLSLAGRGMWRTQARMVWRSGLLLPAVELAVLAAAGFGVLEGRLTVGQVLAALGYVALG
                     MGLITQIPLLTTLSRARSCARRITDVLEAPVPEPGDLGVVPGRGTLELRGVTVEGALRD
                     VDLLVRGGRFTAVVGRSGSGKSALVNVLGGLLTPDEGTATLDGRPLEKLRPYELRAVVG
                     FAFERPALLGATIGDAVGYGSWAGEAAVRAACRSAQVDDLIVRLPDGYRTPLRETPLSG
                     GEAQRIGLARAIAHAPRVLILDDATASLDTVTEAAVEEAIERTLPGRTRVVVTHRAATA
                     SRADTVVWLEDGRVRAVGAHDELWRTPAYRAVFTEGAQ"
     gene            complement(9818..9961)
                     /locus_tag="BLU53_RS44680"
                     /old_locus_tag="SAMN04489733_5594"
     CDS             complement(9818..9961)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949109.1"
                     /locus_tag="BLU53_RS44680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5594"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_123798255.1"
                     /transl_table=11
                     /translation="MELVLDLQALEAPEVLEGGGGGSHGGASNLSLLASCANSTVSLLT
                     CH"
     CDS_motif       complement(9899..9961)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MELVLDLQALEAPEVLEGGGG"
                     /locus_tag="BLU53_RS44680_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9818..9898)
                     /prepeptide="core"
                     /locus_tag="BLU53_RS44680_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="10.40"
                     /molecular_weight="2356.6"
                     /monoisotopic_mass="2355.2"
                     /core_sequence="GSHGGASNLSLLASCANSTVSLLTCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MELVLDLQALEAPEVLEGGGG"
                     /leader_location="[9898:9961](-)"
                     /alternative_weights="2374.6"
                     /alternative_weights="2392.6"
                     /alternative_weights="2410.7"
                     /alternative_weights="2428.7"
                     /alternative_weights="2446.7"
                     /alternative_weights="2464.7"
     gene            complement(10001..12541)
                     /gene="lanKC"
                     /locus_tag="BLU53_RS27315"
                     /old_locus_tag="SAMN04489733_5595"
     CDS             complement(10001..12541)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330827.1"
                     /locus_tag="BLU53_RS27315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5595"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_072029100.1"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1337.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.5e-11, bitscore: 43.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-07, bitscore:
                     30.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVRYEAYCFADPLFFDEQRETGDAADDFASLLPAPGDGWRTGVR
                     GVWRLLHPVARNLPLQGWKIHVSAGLGNAERVLVKVHEHCVEHAVSYKHLRSRTTLLAR
                     NSKYAPRDGSGKLLTLYPADNNELERVLAALSAKLDGEPGAYILSDLRYGAGPLYVRYG
                     GFAEQWVELDGKRVLAIRKPDGTLVPDKREPTFSVPDWVTIPEFLAPHLAARKSGGADQ
                     FPYQVKSSLHFSNGGGVYLADRKSDDERVVLKEARPFAGLDRDEVDAVERLRREHEVLE
                     RLKGIDGIPTAYDRFTVWEHHFLAMEYMPGVSLGNWLARNYPLTRRDTTEADIAAYTQR
                     ALALVRRVEAMVGEVHGRGIVFGDLHSLNILVDGDDDNVSLIDFEMASDIESGTRPALG
                     APGFRAPRDRNGFEVDEYALAVLKLWIFLPLTTLLELAPAKLRGLADFVQQRFDVPEGY
                     ADSIVAELAPRNVPPLTSSTELDQERPDWALVRKQIIEAILASATPERTDRLFPGDIEQ
                     FRVGGACFGYGAAGVLHALHGAGHRHPAHERWLLDSIRRDPPGRPGFYDGSYGIAYVLE
                     ELGYRDEATKLLAASATLVEQTTDHGLEGGLSGIGLTQLHFAVARKDNEFGRQALATAV
                     RLAEALEIADPPGDFGRAGLLNGWSGPALLFVRLFERTREEGWLSFADQALERDIEECV
                     ESDDGSLQVRDGETRTLPYVGVGSAGILMVAEELAKHRPDAKALKSLPGLREACRGEFV
                     IHPGLLFGRGGLMTALAMGAEPDQRVRDAIDLHLSRLAWYAVPYKGGLAFPGNQLLRLS
                     MDVVTGGAGVLLALAATLDGKAALPFLSSRTAVR"
     misc_feature    complement(12191..12193)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12851..12866
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.23"
                     /tool="antismash"
     gene            12968..13333
                     /locus_tag="BLU53_RS27320"
                     /old_locus_tag="SAMN04489733_5596"
     CDS             12968..13333
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020633043.1"
                     /locus_tag="BLU53_RS27320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5596"
                     /product="hypothetical protein"
                     /protein_id="WP_016330826.1"
                     /transl_table=11
                     /translation="MITGFAVTVAICAALVAVWSFVQAARKKLPDNALLAGLAVLEVLL
                     VAQLVIGVVLLIGGGRPGSMATYLAYLIGCLVVLPLGTFWALAERTRASTAILGIACLA
                     IPVMVLRLHEVWAGASA"
     gene            13326..13748
                     /locus_tag="BLU53_RS27325"
                     /old_locus_tag="SAMN04489733_5597"
     CDS             13326..13748
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005163353.1"
                     /locus_tag="BLU53_RS27325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5597"
                     /product="hypothetical protein"
                     /protein_id="WP_172843542.1"
                     /transl_table=11
                     /translation="MPEETEEKTVDTATDKASGPGRILVAVYAIFALAATSRAAVQIST
                     KFGEAPLAYALSAFAAVVYLLATVALARRGAGWWRIALIACGVELAGVLTVGTFSLFDR
                     EAFPHATVWSVYGQGYLFIPLVLPVIGLFWLRRTKP"
     gene            complement(13759..14745)
                     /locus_tag="BLU53_RS27330"
                     /old_locus_tag="SAMN04489733_5598"
     CDS             complement(13759..14745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020633041.1"
                     /locus_tag="BLU53_RS27330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5598"
                     /product="MCE family protein"
                     /protein_id="WP_072029101.1"
                     /transl_table=11
                     /translation="MRSFGAVDPVKVALAGLTTMALGMAAALNADALPVIGGGTTYSAE
                     FSDAGGLRADNDVRIAGVKVGKVSEIDLEGDRVLVSFRVKDAWVGDATSASIQIKNVLG
                     QKYLALDPRGEAILDPGEPIPLRRTTAPYDVLEAFRDLSKTVDAIDVGQLAKSFDTISA
                     TFADTPADVRSALEGIAKLSGTIASRDRQLRTLVANTRQVSQTLVDRDTEAQRLIQDGN
                     ALLRAISTRQQAIKDLLDGSKRLATALDGIIADNDGQLGPVLEQLDRLTSMLQRNQDSL
                     AKGIAAFAPAIRVLTNVAGNGRWIDGYLCGLVLPTFGPLNEKGCFEK"
     gene            complement(14852..15244)
                     /locus_tag="BLU53_RS27335"
                     /old_locus_tag="SAMN04489733_5599"
     CDS             complement(14852..15244)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330823.1"
                     /locus_tag="BLU53_RS27335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5599"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_072029102.1"
                     /transl_table=11
                     /translation="MTELAIGQVTERTGLSVHALRFYEKEGLLAAPVKRDAAGRRVYTE
                     HDVEWLVNCTKFRASGMPLAVIREFAELVRQGPGNEEKRLELLREHQKTVRDRIAELAD
                     CLELISRKVEVYEEHVARGTANELWR"
     gene            15301..16257
                     /locus_tag="BLU53_RS27340"
                     /old_locus_tag="SAMN04489733_5600"
     CDS             15301..16257
                     /NRPS_PKS="Domain: PKS_KR (31-112). E-value: 1.3e-06.
                     Score: 20.4. Matches aSDomain:
                     nrpspksdomains_BLU53_RS27340_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330822.1"
                     /locus_tag="BLU53_RS27340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5600"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_072029103.1"
                     /transl_table=11
                     /translation="MTTAQHKIGSGFGARSTAEEVLNGIDLSGRLALVTGGYSGLGLET
                     TRALANAGAHVVVPARRPADAEAALAGMPGTEVGELDLADLASVDAFARRFLGTGRPID
                     ILIANAGIMAAPERRVGPGWESHFAICHLGHHALVNRLWPALKDGGGARVVTVASSGHH
                     SSPMRWDDVQFERGYDRWLAYGQAKTANVLFAVHLDRLGADHGIRAFSLHPGAILTPLQ
                     RHLRREEMVERGWIDEHGNQADPDFKSPEQGAATQVWAATSPRLEGMGGLYCEDCDVAE
                     IAAEEGEWVGVRPYAIDAGEAERLWKFSAGLTGVPLG"
     aSDomain        15394..15636
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU53_RS27340_PKS_KR.1"
                     /evalue="1.30E-06"
                     /label="BLU53_RS27340_PKS_KR.1"
                     /locus_tag="BLU53_RS27340"
                     /protein_end="112"
                     /protein_start="31"
                     /score="20.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVTGGYSGLGLETTRALANAGAHVVVPARRPADAEAALAGMPGT
                     EVGELDLADLASVDAFARRFLGTGRPIDILIANAGI"
     CDS_motif       15397..15474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU53_RS27340_0001"
                     /evalue="5.90E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="BLU53_RS27340"
                     /protein_end="58"
                     /protein_start="32"
                     /score="22.1"
                     /tool="antismash"
                     /translation="LVTGGYSGLGLETTRALANAGAHVVV"
     gene            complement(16254..17342)
                     /locus_tag="BLU53_RS27345"
                     /old_locus_tag="SAMN04489733_5601"
     CDS             complement(16254..17342)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330821.1"
                     /locus_tag="BLU53_RS27345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5601"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_072029104.1"
                     /transl_table=11
                     /translation="MRRLLVALIALAGLVSLASPAAAAPRLKLPPPTGSHPVGSTDLHL
                     TDSSREDPWVPTGPRELMVSMFYPALVPFGQKRPYLTSAEAKAFLTESGLPDVDPALLS
                     GLRTSARVDAPPLPGRHALVVLSPGFGKPRTTLTGLAEDLASKGFVVALIGHNYESHGT
                     AFPDGHVTECVACGSDSTLLPPIRSADASFVLDTLTRPSSRWSRLIDRTRIGMAGHSIG
                     GYSTPTAMVDDRRIRAGVDMDGRLWSPIPASGIDRPFLLLGRESEYTPAGPDTTWAGSW
                     PNLTGWKRWISVATAGHASFTDVGVLGEQLGLSKPGLLGGERGMQLTRAYVSAFFDANL
                     RGGHQPLLDGPVAENPEIKFWN"
     misc_feature    complement(17328..17343)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.05"
                     /tool="antismash"
     gene            17430..18680
                     /locus_tag="BLU53_RS27350"
                     /old_locus_tag="SAMN04489733_5602"
     CDS             17430..18680
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666154.1"
                     /locus_tag="BLU53_RS27350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5602"
                     /product="sensor histidine kinase"
                     /protein_id="WP_228708045.1"
                     /transl_table=11
                     /translation="MSAARGIREAPARDYARLVLSFLRNHPKAVDIGLTVILGLSTVVA
                     SDDPEGFGWWLTSLVALASLLVRHRSPAITFVTGATVSLLHLAMGNDLRPVDVVALIGL
                     FSVAAWGSRRLSFALLAASLLVTGAWTIHAAESNSREPDPIPPRIIIIDRLAPPEPKDD
                     QVQDWGGFAGIGLSLTVAWLAGLNTRQRRIRLSVLEQRAADLERERDTQAALAVAAERG
                     RISRELHDVVAHALSVVVLQAQGAQAELERRPERTREALDAIVGTGRTALAEIRRLLGA
                     LGQDEPDWEPQPGAERLPRLAADIRAAGTPVEFRVEGEPRPLPSTVDLAAYRIVQEALT
                     NVLKHAGPAASVTIVMRYEPETLEIEVTDDGTAAEEPSGAGHGLEGMRERVNVLGGTFD
                     AGPRPERGFAVRATLPT"
     gene            18677..19324
                     /locus_tag="BLU53_RS27355"
                     /old_locus_tag="SAMN04489733_5603"
     CDS             18677..19324
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005163340.1"
                     /locus_tag="BLU53_RS27355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5603"
                     /product="response regulator transcription factor"
                     /protein_id="WP_063277218.1"
                     /transl_table=11
                     /translation="MTIRVVIADDQSLVRTGLRMILDNADDIDVVGEAGDGAEAVALVA
                     DLDPDVVLMDIRMPEMDGVEATAAIAAAHRARVLVLTTFDLDEYVYAALRAGASGFLLK
                     DALAPDLLAGVRVVASGEATLAPTVTRRLLDRVVTGLPAAPPDDRLALLTGRENEVLRQ
                     LARGLSNAEIAELLFLSPGTVKTHVGRILTKLGLRDRVQAVVFAYESGLISR"
     gene            complement(19314..19958)
                     /locus_tag="BLU53_RS27360"
                     /old_locus_tag="SAMN04489733_5604"
     CDS             complement(19314..19958)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030754.1"
                     /locus_tag="BLU53_RS27360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5604"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_063277219.1"
                     /transl_table=11
                     /translation="MRPDTVSRSALEPEQVGRKVRLREVGLRDRRVLMGFDRDMAREAT
                     PLIGGGHRHWASHRSGSAGDDIHFGIETVRGRMLVGSVCTIGADPATGKFGYGIGIAPR
                     HQRCGYATDAITVLLAHMFGQRGFRKCEVSVYGGNLASLSLHGGLGFREEGRLADTEVV
                     RGEIKYLVRMGITAEEFAARPPAALGDLGRRGQHRRPRRGKHWRTPAAVSG"
     gene            complement(20062..20265)
                     /locus_tag="BLU53_RS27365"
                     /old_locus_tag="SAMN04489733_5605"
     CDS             complement(20062..20265)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441988.1"
                     /locus_tag="BLU53_RS27365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5605"
                     /product="cold-shock protein"
                     /protein_id="WP_016330817.1"
                     /transl_table=11
                     /translation="MAQGSVKWFNGEKGFGFIAQDDGGPDVFVHYSEIQGTGFKSLDEG
                     QRVEFEIGQGQKGPQAQRVVAI"
     misc_feature    20265..20274
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.1"
                     /tool="antismash"
     misc_feature    complement(20576..20591)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(20577..20591)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    20633..20647
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            complement(20754..21662)
                     /locus_tag="BLU53_RS27370"
                     /old_locus_tag="SAMN04489733_5606"
     CDS             complement(20754..21662)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330816.1"
                     /locus_tag="BLU53_RS27370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_5606"
                     /product="hypothetical protein"
                     /protein_id="WP_063277220.1"
                     /transl_table=11
                     /translation="MDLKHAVRRIAALSAAFGAATVAVAAPATADDQVVTVVSEADRAA
                     ALAHWTPERMRQWVGDEDLPPAEKIGRAWEGPVPPGVGRLFFTAEPGVDGSCTATVVPS
                     VSKDVAFTAGHCVNGGLDRFDRPIKIVNVVFVPGYDRGAAPHGVFPARSFAWSSTYAGP
                     MSGSDDDAVIALDPVGGRHVADVAGTQDISFEELPSTVDTTMFGYPVSRAAGGEALFSC
                     VRPATREANSVTTTWNTDCDLAGGSSGGPWLRNFDPASGKGTIFSVTSRGTMTEDGVTT
                     DLSGAAFTEPVRKLYERAGEL"
     misc_feature    21925..21939
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.82"
                     /tool="antismash"
ORIGIN
        1 cagtgtgccc gggtggcacg gggagcggaa ggtctctgtg acctgggcgc gggctatccg
       61 gggaagggtg cgtccgccag gcgtggggtg ggaagggccg ccgtcggctt cctgccgagc
      121 agcaggccgg tcctggtggc ctcggccatc acggcgcgga cgtcgacgca ccacggcccg
      181 tcgggcttca attcgacgaa agcgctctct cccggcttga gcacgaaatg cggctggccg
      241 tccagcgcga tggagccacc gccggcggcg agatcgacgc ggacaccggc gtgcagcacg
      301 ctccagccgc ggacgcccac ctcccggacc tcgccgggcg cgatcggcgc ctgcaccacg
      361 tacggtgtct cgtcgaccgg tccgagcgag accgcgacac cgtccacagt ggacttcggg
      421 ctggggcaga gccgcccggg gatactcgac agcccgaccc cgtccggaac cgcgaacgtg
      481 cagtacagct cggtcagcga cgcgggatcc caccggctct ccgagcacac gctgacgtcg
      541 gtcagcgcga tctcacggcg ggccttcgtg acgacctcga gcacggtggc gcggttcgtg
      601 accaggtccg tgtccacctg atgagtggcc accagcccgg cggcgagccc ggcgacggtg
      661 gactcgtcgg cgccaccggc gggcagcatc agcagcggga cgtcaccgca ggcggccgcc
      721 gcggcccgca tcatgctctc gttgccgagg cagatgagca cgctcgcacc cgcgtccacc
      781 atccggcgga cggtgccgat gatcttgccc gcgtcggccc acaccatcac gcggccgacg
      841 ccggccaccc tcagtgccga acgcaggccc tggatgtcac gctccgaagc ggggttcgcc
      901 acgatccccg caaccgcttc gcccacatgt cctccgctgc cgcgccaagt ccctacaagg
      961 aaacgacgtc cgggccacga aagaaagagt tgcacgaggt tgcatcacca ggaaagggca
     1021 cgggactttt ggtcaacggg ccgcctgccc gtcaggacac ggacgccgag cggcacgagc
     1081 gccaggccga gggccaccgc ggtgacgacg ctcaggaact cgctctcctt gagcaccccc
     1141 atccagagcg tgcacggcca gaggaacagc agcgcccgcc cggtgccgaa ggtaccggcc
     1201 cggaacgccc cgatggccag tagcaggcct ccggcgtact ggccgaccga cgcggtgacc
     1261 gggatccgcc acaggccgta ggacaggtcg acgtagtcgt ccatcaccag cctcgtcgcc
     1321 tgctccagtc cgagcttgtc gacgagctcg aaggccgcca ggtcgacgcc tgcgaagtag
     1381 acccgcgcga acaagccgag cgcgaggagc aggaaccccc aacctgccaa cgccggcgcc
     1441 ttctccgcga cgatcttcgc cagcatcagg aaggccggca gcaggaggat cgcgccgagc
     1501 aggaagaccg agtacgcggc cgtcaccagg ccggggttcg cggcgtacgc ggccagctgc
     1561 ccgggggcgg cgaagggctg ctcgtcgaac cacgcgactt gctccggcgt gaagtccttg
     1621 agcaccagat gtcgcaacag caggcccgcg aaccagacga gcggggcgag aatcagggcc
     1681 actccgccga tccagcggcc ggtttcaccg ttcatgccgg aatcgtcgcc gggacgggcg
     1741 gcgcgggaca gcgcccgaaa gtcaggcgcg ggccccgact ttcgtcagga tcggtcccgg
     1801 aaaagcagca gggccgcctc cccgagggga tgacggccct gcttggaaaa cctggatcag
     1861 atcacggtga ccgaggtggc ctgcggaccc ttcgcgccct gcccgatctc gaactccacg
     1921 cgggcgttct cctcgagggt acggaagccg ttgcccttga tctcgctgta gtgcacgaag
     1981 acgtcgccgc cgccgttgtc gggagtgatg aagccgaacc ccttctcgga gttgaaccac
     2041 ttcacagtgc cctgagtcat aaaatctcca tatgcaacac aaacaaacag gaagccacgt
     2101 cggcagcccg ggtcatgacc agacggtttg cttccccgga aacacgagga gacactacgc
     2161 ccgctgagtt ctgcgagcgt gaaccaacac gaacacaaaa atcgagacct ggtgcagtaa
     2221 agcacacctc acgcaggccg acaagcgcca tcacccgggt gtgcgcagcc gcactgcacc
     2281 ttttggcgac tgtacctctc cggccgaagt ggcgaccggc cgggctattc gccgctggcg
     2341 gcgcgcaggg gtacctcggt gccgaacggc gagcggcgca gcgcctcccg gttcgtggcc
     2401 acgacggcga tgtcgtgggt ctccgcgtcc gcgctgaaca gcaccggcac cacgccggaa
     2461 acggacttgt cctgtggctt cgcttcgtca gccatgtttt ctcccagtgt caacacaacg
     2521 ctctacgtac gtactgcgtg ccaacaacca caccggccat tgccccggtc catatcggac
     2581 tctcggtgtt gccgcgattg tgccacggcc gaccgacaaa atccggtgtc cgcgaccgaa
     2641 agtcggccga gtcgtcacct cgttcccacc ctttggggca ggtgaaggcg gcgccacaag
     2701 ggtttctgtg tatcccctga gaaaaagtac cgcccggtag tcggcgtggc ggcccctact
     2761 ggccgccctg ctgcggcctc gcggcgccca gcaggctcgt cagccggatg tccggggtca
     2821 ccacgtccgg atccgtgcgg atgtcgatca cacaaggccg ttgccgcacc agcgcgctcg
     2881 cgatgatcgg ctccagctct tcccgatcgt ccacggtgta cccggcggcg ccgagcccgc
     2941 gtgcccacga cgcgaagtcg gtgatgggga cggtgacccc cgacagccgg ccgtgtttgc
     3001 gcgcctggtg cacggcgagc gggccgtgca ccccgttctg gaacaccagg acggtcaccg
     3061 gcacccggta gcgcacggcg gtctcgatct cctgcccggt catcagcgcg ccaccgtcgc
     3121 ccgccatcgc gatcaccgtc cggcgtggtt cggcgagttt cgccgcgacc gccgcgggca
     3181 ccgcgtagcc catggccgcg ttgctcggcc cgagctggct gcgcggcgcg gtgaaacacc
     3241 agtagcggtg catgaactgg gcgaagttgc ccgcgtcgct ggtcacgatc gcgtcttcgg
     3301 gcgcgagttt gcgtaccgcg cggatgacgt cggcggggtg gacgcgggtg gcgccgctgg
     3361 tgtcgggcgg cgtcatgaag gtgtgcaccg cggcgttcgc ggccgacgcg cgccgctgcc
     3421 ggggcgaggc gacattgcgc agttcacgca ggaagggctc gacctcggag tcgacccgga
     3481 aggtcaggcc gccgcggcgg gcgggctcga tcccggtgcc gaccagcacc agcgtctgcg
     3541 acggcgtcgg gtaccgaaag gactgagtgg tgacctcgtc gagctgcgtg cccagcgcga
     3601 gcacgaggtc cgcgcgctcg agcgcgtcga gctgccgcgc ggggatgccg atgccgagat
     3661 ggccggcgta gcgcgcgtgg ttctcgggga aggcgtcctg gcggcggaac gcgttgtaca
     3721 ccggcaacgc gagctcgtcg gcgacggcga tcagctcgtc gcgcgccgcg cgggcccggc
     3781 cgccgacgat caccaccggg tagcgggcct cgtcgaccag ctgcgcgacc gcctcggcgg
     3841 tccggccgag cgcgccggtg gcgggcgggc gcacggcggc gaccggtttg gccgaatcga
     3901 acgggacacc ccagaaatcg gcggggacgg cgacgacggt gggtcccggc cgcccctcgc
     3961 ggcagcgggt cagcgcctcg accagcagac cgggcacctc gtccggcgat tccgcgcggc
     4021 cggtccactt cgagatcggc tcgaacatcg cggtcaggtc cgcggtgggc aactcgctcg
     4081 tcgggccggg atcctgcggc gggttctcca ggaggacgac catcgggctc tcgtcctggt
     4141 acgccgtgga gacaccgatc gcgaggttcg ccgcgctcgg gccgcggccg gcgagcagga
     4201 ccgcggggtg ctcggtgagc ttgccttcgg cctcggccat gaaggcggcg ccggagtcgt
     4261 gcctcgccga aacgaaggtg atcgagcgct cgcgttgcag tgcgtcgagc agatccagga
     4321 aggactcacc caccaccgcg tacacgcggt ggatctgcgc ctcggtcagg atccgcacgg
     4381 ccgtctgggc gacggacgct cccggttggt atctaatgag aagagcttag gcgggcggtg
     4441 atcggtgccg tcaagcgatc ttccgattcc ggcaaccccg gagcggcgga atgtccgata
     4501 ttcggaacgt gttcgagcaa gggagcacga aaacgtgacc tcagccaccg ccggacgtga
     4561 aactgttttc acttacgggg cgcctgcctt gaagtacggc accgggtcga gcgatgagat
     4621 cggctacgac ctcacccagt acggcgcccg ccgggtgctc gtcctgaccg acccgggtgt
     4681 cgccgcgacg ggctggccac aacggatcgc cgaaggcatc gaaacctatg gcatcgaagc
     4741 cgtcgtcttc gacggcgtcc acgtcgagcc gaccgacgtc agcatgcgga aggccgtcga
     4801 cttcgcccgc ggacagggcg aatgggacgc cttcgtcgcc gtcggcggcg ggtcggccat
     4861 cgacaccgcc aaagcggtga acctgttgac cagcaacgac ggcgacctga tggactacgt
     4921 caacgcgccg gtcggcggcg gccgtgcccc gagttcgccg ctgaaaccgc tggtcgcggt
     4981 gccgaccacc accgggacgg gctccgagag caccacggtc tgcgtgctgg acgtgttgtc
     5041 actgcgggtg aagagcggca tcagccatct ccggatgcgg ccgagcctcg cggtggtcga
     5101 tccgaggctg acggtctcgc agccgcccga ggtgaccgcc gccagcggga tggacatcct
     5161 ttgccacgcc gcggaaagct acacggccaa gccgtacacc gagttcgacc ggaagcggcc
     5221 ggaggaccgg gttccttact gtggctcgaa tccgctggcc gacatgttcg ccgagcagtc
     5281 gctgcggctg ctgtcgtggg ccctgcccgc agccgtgcgc gatggctccg acatgaaggc
     5341 gcgcgaggcg atggcgctcg cggcgacgtt cgccgggctc ggtttcggca acgccggggt
     5401 gcacatcccg cacgccaacg cgtatccgat cgccgggcag gtgcgggaat tccatcctcc
     5461 ggggtatccg ggcgacgaag cgatggtgcc gcacgggatg gccgtctcgc tgacggcgcc
     5521 ggcggcgttc cggttcacct tcgacgccgc gccggaccgg cacatccggg tggcgcggct
     5581 gctcgccccg gactacgaat ggccgggcga tctccgggat catctgcccg cggtgctcgg
     5641 gcagatcatg cgggagatcg ggatccccaa cgggatcggc gccgtcggct acaccgagtc
     5701 cgatgtggac tcgctggttt ccggcacggt gaaacaacaa cggttgctgg cgacggcgcc
     5761 gcgcgaggcg tccgaagcgg acctcgcggt gatcctgcgg gagtcggtga cgctgtggtg
     5821 aacgccgagt atccgcactg gcagacggtt ccgttgcggt ggaaggacaa cgacgtctac
     5881 gggcacgtca acaacgtcgt ccactattcg gtgatggaca ccgtgatcaa cacctggctg
     5941 atcgaacgcg gcggcctcga catcgagacc ggcgcggtca tcgggttgtg cgtggagtcg
     6001 cagtgcaaat accacgcttc ggtgtcgttc ccgggagaac tcgaagtcgg cctgcgggtg
     6061 ggccacctcg gccggtccag tgtccgctac gaggtcggga tgtactcgaa ggagacggtg
     6121 atcgcggagg ggcatttcgt gcacgtcttc gtcgatcgcg aatcccggcg cccggttccc
     6181 gtcgagggtc tactcaggag cgcgctggaa gaactgcgca ctgggctggg gtagccgcgg
     6241 cgaccacgcg tgcatgagct gggcgtagcg cgtggaccgg tccatgagtt cgaggtgggt
     6301 gcccagggcg gtctccttgc cgtccatcac caggacccgg tccgcgcgca gcgccgacgt
     6361 cagccggtgc gcgatcacca ccagcacccc gccccgctcg gcgaacgccc gttccgcgcg
     6421 ggcttcggcg ggcgggtcga ggtgcgacgt cgcctcgtcg aggatgacga cggtcgctcc
     6481 gctcgcgtac acccgcgcga gcgcgatcaa ctgcgcctcg ccggcggaca gcgtgccgtg
     6541 cccgatctcg ccgtcgagcc cgcccagccg cgtgaccagc ggttccgcgc cgacggcccg
     6601 caccgccgcc agcagttcgc cgtccatcgc ggtctgcgcg aacaggccga cgttgtcccg
     6661 cacggtcccg gcgaagacgt acgcctcctg cgggatcagc gcgaccatcc ggtgccgcag
     6721 ggccgccggg acttcgcgga ccggcacccc gccgagcagc acccggccgg cctgcggggc
     6781 gagcatgccg gtcagcagcc ccgccaaagt cgacttgccg attccgctcg gccccaccac
     6841 cgcgagccgc tcgccgggcc gcagatgcag gtcgagcccg cgcaccaccg gttgcgcggc
     6901 cgcgccccag ctgaaggtca ggtcgcgcac gtagatcgcg gtcccgtcgg gttcggccgt
     6961 gccgtcggcc tccggctcgc cctcggcggt ctcggcgagc cgccgcagcg cgacgatcag
     7021 ccgcagcacc acggtgctcg ccgtcgcggc gagtccgcgc aacgcgggct gcatcgtcgt
     7081 cgccaggtag acgagcgcgc cgagcgcggc accggcggtg agcaccccgg cctggaccat
     7141 gcccggcgcc accagcaacg ccagcagcag cggcacgaaa ccgccggtcg cgatcaccac
     7201 cgtgcgggcc gccccggacc gcgccacccg cacggccgcc ttggcctgcg tgtcgatggc
     7261 gtcgtaaagc tccagcgcgg caaggggttc ggcgccgcac gcgacgatgt cacgcatacc
     7321 ggacaacgac gcgcccgcga cctcggcggt ccgctcgtcg gccagcgcga gcgcgcgctg
     7381 gcgccgcgcc agcgacggga gcaggcaggc gaacacgagg accgagacca ccaccgggat
     7441 cgccacgatc aacgcgagcg aaccggcgac ggtgaacaac ccggccagcg ccgccaccgt
     7501 cgtcacgatc atcccgcgcg cctgcaccag cagcccggcc gtggcgtcgc gcaccacctc
     7561 gacgtgctgg gtgatgcgcg cgacgccgct ggcgtccggc tgattgcgcg gtggcgccgg
     7621 atcgtgcagg accccgcgca cgacggcggt caccagcgcg tcgcgcaacg gctcgacgac
     7681 cttgccgagc tgatgccaca ccagccgcga accgaacgcg ccgatcacgg cgaccagccc
     7741 gaagaccgcg agccaacgca gtccggtgcc tggccgatcc gcggcaaacc cctcgtcaac
     7801 cgcgagttcg accaggcgac cggacaagaa cgcgggcgcg ctctccagca cggagcaggc
     7861 cagcagcacc agcccgccgc gccactgccc ggccagcgcc gagcggtaga gcccccagac
     7921 gctcattgcg cgccctcggt gaagacggcc cggtaagccg gagtccgcca cagttcgtca
     7981 tgcgcgccga ccgcccggac ccggccgtct tccagccaca ccaccgtgtc cgcccgcgac
     8041 gcggtggccg cgcgatgcgt caccaccacc ctggtccggc cgggcagcgt gcgttcgatc
     8101 gcctcctcga cggcggcttc ggtgaccgtg tccaggctgg cggtggcgtc gtcgaggatg
     8161 agcacccgcg gcgcgtgcgc gatcgcgcgg gccagcccga tccgctgcgc ctccccgccg
     8221 gagagcggtg tttccctgag cggcgtccgg tagccgtccg gcaaccggac gatcaggtcg
     8281 tcgacctgcg cggaccggca ggcggcacgc acggcggcct caccggccca cgagccgtag
     8341 ccgacggcgt cgccgatcgt cgcgccgagc agcgcgggcc gttcgaaggc gaacccgacc
     8401 accgcgcgga gttcgtacgg ccgcagcttc tccagtggac ggccgtcgag cgtcgccgtc
     8461 ccctcgtccg gggtcagcag tccgccgagg acgttgacca gcgcggattt ccccgaaccg
     8521 gaccgcccga cgaccgcggt gaaccggccg ccccggacga gcaggtcgac gtcgcgcaac
     8581 gcgccttcga cggtgacgcc gcgcagttcg agcgtgcccc gccctgggac gacgccgagg
     8641 tcacccggct cggggaccgg cgcctccagc acgtcggtga tccgccgcgc acacgaccgg
     8701 gcgcgggaaa gtgtggtgag caagggaatc tgcgtgatca gccccatgcc gagcgcgacg
     8761 tagccgagcg ccgcgagcac ctggccgacg gtcagcctgc cttccagcac cccgaacccg
     8821 gcggcggcga gcaccgcgag ttcgaccgcg ggcagcagca gcccggagcg ccacaccatc
     8881 cgggcctgcg tgcgccacat cccgcggccg gcgaggctca gcttcggcaa cggccgcagc
     8941 acacggtcgg cttcgcggtc ggcggtgccg gacgcggcga tcgtgcggag cccggcgacc
     9001 gcgtcgacca tcctcgccgc gagctcgccg gacacctctt gataggtgag gacgtcgtcg
     9061 gcggtgttct tcaggtgagt gcgcgcgagc atcaggccga acgggatgct gccgaggaag
     9121 accagcgcga gccgccagtc catcagcgcc agcaggacga cggccccgcc ggagatcagg
     9181 gtggtcgacc cgagctggac gacgaccgag gcgaccagtc ccgcgccggt gcagtcgccg
     9241 gtgagcctgc tgatcgcgtc gccgtcggcg aaggtcgatc gggtgccgag tgcgagatag
     9301 cggtcggcga gttcgcggcg cagccaggcc gtggcggacg cggtcatccg cgcggtgagg
     9361 atgccgccga tcaggccgac ggcgatctcg gtgacgccga ggacgatcag ccaggtgacc
     9421 tcgggcaggc tgggccgtcc ggccacgacc gcgtcgaccg cggcggcgag cgcgccgggc
     9481 aggagcagcc ccgccgccgt cccggcgagc gcgctgagga tcagcgcgat caggcggggg
     9541 cgatccagcg cggtcacctt gaccagcaac cgatcggcgg aacccgccat cccactcctt
     9601 agtcttggtt caggggcgct tcccggtagg ggccggcagg tcggtccggt gggtcgtgag
     9661 tggcgattcg ggttctaacc cgaatcgcca ctcacgaccc acccgacccg ctcctcacac
     9721 cgtgatccca acgagatgaa ccggaaggca aaatgaaggc gcgggagcgg cgcacttggc
     9781 ctgtgccgct cccgcgcctt cagtgctcag ccgtgactca gtggcaggtc agcaggctga
     9841 cggtgctgtt cgcgcaggag gccagcaggc tgaggttgct cgcgccgccg tggctgccac
     9901 cgccgccgcc ttcgagaacc tcgggggctt ccagggcctg caggtcgaga accagttcca
     9961 tggtgttccc tttcactagt tacctcttgg tccgccgtcc tcatcggacg gcagttcggg
    10021 aggacaggaa aggcagcgcg gccttcccgt ccagggtggc ggccaaggcg agcaggacgc
    10081 ccgcgccgcc ggtgacgacg tccatcgaca gccgcagcag ctggttgccg gggaacgcca
    10141 gcccgccctt gtacggcacc gcgtaccagg ccagccggga aagatgcagg tcgatggcgt
    10201 cgcggacgcg ctgatccggt tcggcgccca tggccagcgc ggtcatcagc ccgcctcggc
    10261 cgaacaacag cccgggatgg atgacgaact cgccgcggca cgcttcacgc aggccgggaa
    10321 ggctcttcaa cgccttcgcg tccggacggt gcttcgcgag ttcctcggcg accatgagga
    10381 tcccggcgct gccgacaccc acgtagggca acgtccgggt ctcgccgtcg cggacctgca
    10441 gcgagccgtc gtcggactcg acgcattcct cgatgtcccg ctccagcgcc tggtcggcga
    10501 aggacagcca gccctcttcg cgggtgcgtt cgaacagccg cacgaacagc agcgccggac
    10561 cggaccagcc gttgagcagc ccggcgcggc cgaagtcgcc gggcgggtcg gcgatctcga
    10621 gtgcttccgc gagccggacg gcggtggcga gcgcctgcct gccgaactcg ttgtccttgc
    10681 gggccaccgc gaagtgcagc tgggtgagcc cgataccgga caagccgcct tccagaccgt
    10741 ggtcggtggt ctgctcgacc agcgtcgccg acgccgccaa gagcttggtg gcctcgtccc
    10801 ggtatccgag ctcttcgagg acgtacgcga ttccgtacga gccgtcgtag aaccccggcc
    10861 gtccgggcgg atcgcggcgg atcgagtcca gcagccaacg ctcgtgggcg ggatgccgat
    10921 ggcctgcccc gtgcagggcg tggaggacgc cggccgcgcc gtagccgaag cacgctccgc
    10981 cgacgcggaa ctgctcgatg tcgccgggga agagccggtc ggtgcgctca ggggtcgcgc
    11041 tggcgaggat cgcctcgatg atctgcttgc ggaccagcgc ccagtccggt cgttcctggt
    11101 ccagctcggt gctgctcgtg agcggcggca cgttccgggg cgcgagctcc gcgacgatcg
    11161 agtcggcgta gccctccggg acgtcgaagc gctgctggac gaagtccgcg agcccgcgca
    11221 gcttcgccgg ggcgagctcc aggagcgtcg tgagcggcag gaagatccac agcttcagga
    11281 cggcgagcgc gtactcgtcg acctcgaacc cgttccggtc cctcggggcg cggaagccgg
    11341 gcgcgccgag cgcgggccgg gtgccgcttt cgatgtcgga cgccatctcg aagtcgatca
    11401 aggagacgtt gtcgtcgtcc ccgtccacca ggatgttcag cgaatgcagg tcgccgaaga
    11461 cgatcccgcg gccgtgcacc tcgccgacca tcgcctccac ccgccggacc agcgccagcg
    11521 cgcgttgggt gtacgcggcg atgtcggcct cggtggtgtc gcgccgggtg agcggatagt
    11581 tgcgggcgag ccagttaccg agcgagacgc cgggcatgta ctccatcgcc aggaagtggt
    11641 gctcccagac ggtgaagcgg tcgtaggcgg tagggatgcc gtcgatgccc ttcaagcgct
    11701 ccagcacctc gtgctcacgg cggagacgct cgacggcgtc gacctcgtcg cggtccaggc
    11761 cggcgaacgg cctggcctcc ttgaggacca cacgttcgtc gtcggatttc cggtcggcga
    11821 ggtacacgcc gccgccgttg gagaagtgca gagaactttt cacctgatag gggaactgat
    11881 ccgcaccgcc gctcttgcga gctgcgagat gaggcgcgag gaactccgga atcgtcaccc
    11941 agtcgggtac ggagaaggtc ggttcacgct tgtccgggac cagcgtcccg tccggtttgc
    12001 gtatcgcgag aacccgcttg ccgtcgagtt cgacccattg ctcggcgaat ccgccgtagc
    12061 ggacgtagag cggcccggca ccataccgaa gatcactgag aatgtacgcc cctggttcgc
    12121 cgtcgagctt cgccgacaac gccgcgagaa cacgctcgag ctcgttgttg tcagccggat
    12181 aaagagtcag taacttaccg cttccgtcac gcggggcgta tttcgaattc ctggcaagca
    12241 gggtcgtccg cgaacgcaga tgcttgtagg acacggcgtg ctcgacacaa tgctcgtgca
    12301 ccttcacgag cacccgctcg gcgttgccca gacctgccga cacgtggatt ttccagccct
    12361 gcaagggaag gtttcgagca acagggtgca acaaccgcca cactccgcgc accccggtac
    12421 gccagccgtc cccgggagcg ggcagcaggg aggcgaaatc gtcggcggcg tccccggttt
    12481 cccgctgttc atcgaagaac agtggatcgg cgaagcaata cgcttcgtac cggacgtcca
    12541 tcgagcgccc cctccttggc accaatcgga tgggccatgt gcaccatcgc gatgcagaat
    12601 attccacctg ccggaccccg aacggccaat ccgccatatc gggggttcgg atgggctgtt
    12661 cagggacgtg aattcgaaaa ctaccgaatg gtaggggtac ccagcgtgag atcaactcgg
    12721 attccaacca cccggtcggt gtgtaacagg aacgaaccgg cgtcgtaatc ccaggtcgag
    12781 gcgccgaacg caataacgca cgagggaatt gacagtgcgc caatccggcg cgtttcgtga
    12841 tctattcacc cgaggtctgg accactgccc cggcccgtgg cgcccgccac gcggcccacc
    12901 ggtcgcccgt cggcggtgat ccgcccggag gtacgttgtc gccggtggag cgggtaagga
    12961 ggccgacgtg atcacagggt tcgcggtgac cgtcgcgatc tgcgcggcgc tggtcgcggt
    13021 gtggagtttc gtccaggcgg cacgcaagaa gctgccggac aacgcgctgc tcgccggcct
    13081 cgccgtgctc gaagtcctcc tggtggccca gctcgtgatc ggggtcgtcc tgctgatcgg
    13141 cggcggccgc cccggcagca tggccaccta tctcgcgtac ctgatcggct gcctggtcgt
    13201 gctcccgctc gggaccttct gggcgctggc cgagcgcacc cgggcgagca ccgcgatcct
    13261 cggcatcgcc tgcctcgcca tcccggtgat ggtgctccgg ctgcacgagg tctgggcggg
    13321 cgcaagtgcc tgaagaaacc gaggagaaga cggtggacac cgcgacggac aaggcctccg
    13381 gcccgggacg gatcctggtc gccgtgtacg cgatcttcgc gctggcggcg acctcacgcg
    13441 ccgccgtgca gatcagcacc aaattcggcg aagccccact ggcgtacgcc ctctccgcgt
    13501 tcgcggccgt cgtgtacctg ctggccaccg tggcgctggc ccgccgcggc gcgggctggt
    13561 ggcggatcgc gctgatcgcc tgcggcgtcg agctggccgg cgtgctgacc gtcggcacgt
    13621 tcagcctctt cgaccgcgag gccttcccgc acgccaccgt gtggtcggtg tacgggcagg
    13681 gctacctctt catcccgctg gtgcttccgg tgatcgggct gttctggctg cggcggacga
    13741 agccctgacg gaggccgctc acttctcgaa gcagcccttt tcgttgagcg ggccgaacgt
    13801 gggcaggacc agcccgcaca ggtagccgtc gatccagcgg ccgttgcccg cgacgttggt
    13861 gagcacccgg atcgccggcg cgaacgcggc gatccccttg gccagcgaat cctgattgcg
    13921 ctggagcatc gacgtcagcc ggtcgagttg ttcgagcacc ggacccagtt gcccgtcgtt
    13981 gtcggcgatg atgccgtcga gcgcggtcgc gagccgtttc gagccgtcga gcaggtcctt
    14041 gatcgcctgc tgccgggtgg agatcgcgcg cagcagcgcg ttgccgtcct ggatcagccg
    14101 ctgggcctcg gtgtcgcggt cgacgagggt ctgcgaaacc tgacgtgtgt tcgcgacgag
    14161 cgtccggagc tgccggtccc gggaggcgat ggtgccggag agcttcgcga tcccctcgag
    14221 cgcggagcgg acgtcggcag gcgtatcggc gaaagtcgcg gaaatcgtgt cgaagctttt
    14281 cgccaattga ccgacgtcga tggcgtcgac ggttttcgac aaatcccgaa acgcttcaag
    14341 gacgtcgtac ggcgcggtgg tccgccgcag cgggatcggt tctccggggt caaggatcgc
    14401 ttcgccgcgc gggtcgagcg ccaagtactt ctgccccagg acgttcttga tctgaatgga
    14461 cgcgctcgtg gcgtcgccga cccaggcgtc cttcacccgg aaggagacga gcacgcgatc
    14521 gccttcgagg tcgatctcgg acaccttgcc gaccttcacc ccggcgatcc ggacgtcgtt
    14581 gtcggcgcgc agcccgcccg cgtcggagaa ttcggcggaa tacgtggtgc cgccgccgat
    14641 caccggcagg gcatccgcgt tgagcgccgc cgccatgccg agggccatcg tggtgagccc
    14701 ggcgagcgcc accttgaccg gatccaccgc gccgaaggac ctcatcgtct cacctcgcag
    14761 gtcacgagcg gcaaagctta ggggccgccc ctgcccatcg ccaggcgaaa cgttgcaccg
    14821 atcgggtggc agcgtctgtc cactatggac tctagcgcca gagctcgttc gcggtccccc
    14881 gcgcgacgtg ctcctcgtag acctcgacct tccggctgat cagttccagg caatcggcca
    14941 gctcggcgat ccggtcgcgg acggtcttct gatgttcccg cagcagctcg agccgctttt
    15001 cctcgtttcc gggcccttga cggactagtt cggcgaattc gcggatgacg gcgagcggca
    15061 ttccggacgc ccggaacttc gtgcagttca ccagccattc gacgtcgtgt tcggtgtaca
    15121 cgcggcgccc ggccgcgtcc cgtttcaccg gtgccgcgag cagcccttcc ttctcgtaga
    15181 agcgaagcgc gtgcacgctg aggcccgtcc gctcggtgac ctggccgatc gcgagttccg
    15241 tcaccaggct gacgatagcg ccttgaccta gagggccctc tagctcttag cgtccgcctc
    15301 atgaccaccg cacaacacaa gatcggttcc ggtttcggcg cgcgcagcac cgcagaagaa
    15361 gtactgaacg gcatcgacct ctccggcagg ctcgccctcg tcaccggcgg ctattcgggg
    15421 ctgggcctgg aaaccacccg ggcgctggcg aacgccggcg cgcacgtggt cgttcccgcg
    15481 cgccgtccgg ccgacgccga ggccgccctc gccgggatgc caggcaccga ggtcggcgag
    15541 ctcgacctcg ccgatctggc gagcgtcgac gccttcgccc gccgcttcct cggcaccggc
    15601 cgcccgatcg acatcctgat cgcgaacgcc gggatcatgg ccgcgccgga acggcgcgtc
    15661 ggccccggct gggagtcgca tttcgcgatc tgccatctcg gccaccacgc cctggtgaac
    15721 cgcctttggc cagcgctgaa ggacggcggc ggcgcccgcg tcgtcacggt ggcctcgtcc
    15781 ggccatcact cgtcaccgat gcgctgggac gacgtccagt tcgagcgcgg ttacgaccgc
    15841 tggctcgcct acggccaggc caagacggcg aacgtgctgt tcgcggtgca cctggacagg
    15901 ctcggcgccg accacgggat ccgcgcgttc agcctgcatc cgggcgccat cctcactccc
    15961 ctgcagcgtc atctgcggcg ggaggagatg gtcgaacgcg gctggatcga cgagcacggg
    16021 aaccaggccg acccggactt caaatcgccg gagcagggtg ctgccaccca ggtctgggcg
    16081 gcgacgtccc cgcggctcga agggatgggc gggctctatt gcgaggactg cgacgtcgcc
    16141 gagatcgccg ccgaagaggg cgagtgggtc ggcgtgcgcc cctacgcgat cgacgccggt
    16201 gaggccgagc ggctctggaa gttctccgcc ggcctcaccg gggtccccct cggctagttc
    16261 cagaacttga tctcggggtt ctccgccacc ggcccgtcga gcaagggctg gtgcccgccg
    16321 cgcaggttcg cgtcgaagaa cgccgagaca taagccctgg tcagctgcat cccgcgctca
    16381 ccaccgagca gaccgggctt gctcagcccg agctgctcac ccagcacgcc gacgtcggtg
    16441 aaggacgcgt gcccggccgt cgcgacgctg atccagcgct tccagccggt gaggttcggc
    16501 cagctgccag cccaggtcgt gtccgggccg gccggggtgt actcgctttc gcgcccgagc
    16561 agcaggaacg gccggtcgat gccggacgcg gggatcggcg accacagcct gccgtccata
    16621 tcgacgcccg cccggatccg ccggtcgtcg accatcgcgg tcggcgtgct gtacccgccg
    16681 atggaatgcc ccgccatccc gatccgcgtc cggtcgatca gccgggacca gcgcgacgaa
    16741 ggcctggtca gggtgtcgag gacgaaggag gcgtccgccg agcggatcgg cgggagcaac
    16801 gtggagtccg acccgcaggc gacgcattcg gtgacgtgcc cgtcggggaa tgcggtgccg
    16861 tgggactcgt agttgtggcc gatcagcgcg accacgaaac ccttgctcgc caggtcttcg
    16921 gccagcccgg tgagcgtggt gcgcggtttg ccgaatcccg gcgacaggac cacgagcgcg
    16981 tgcctgcccg gcagcggcgg ggcgtcgacc ctggcgctgg tccggagccc ggagagcagc
    17041 gcggggtcga cgtcgggaag gcccgattcg gtcaggaacg ccttcgcctc ggccgaggtg
    17101 aggtagggcc gtttctgacc gaacggcacc agcgcggggt agaacatcga caccatcagc
    17161 tcgcgcggcc cggtcggcac ccaggggtcc tcgcgcgaag agtcggtcag atgcaggtca
    17221 gtggagccga cgggatgcga accggtcggc ggcggcaact tcagccgtgg agccgccgcg
    17281 gccgggctcg ccaacgacac caggccggcg agggcgatca gtgcgacgag aagccttctc
    17341 atgaggattc cgtttctgtc ggggatcttc ctggcgtcca gcctgggacc cggtgccgta
    17401 ttcgcgcgtc tgccgcaggt cgtatcccga tgtctgccgc gagagggatc cgcgaggccc
    17461 cggcccggga ttacgctcgg ctggtgctct ccttcctcag gaaccacccg aaagccgtgg
    17521 acatcgggct gaccgtgatc ctcggactgt ccactgtggt cgcgagcgac gacccggagg
    17581 gcttcgggtg gtggctgacc tccttggtgg cgttggcttc cctgctcgtc cgtcaccgca
    17641 gtcccgcgat caccttcgtg accggcgcga ccgtctcact cctgcatctg gccatgggca
    17701 acgatctccg cccggtcgac gtcgtggcct tgatcggcct cttctcggtc gcggcttggg
    17761 gttctcggcg gctttcgttc gcgctgctgg cggcgagcct gctggtcacc ggcgcgtgga
    17821 cgatccacgc cgccgaatcg aattcgcgcg aaccggatcc gataccaccg cggatcatca
    17881 tcatcgatcg gctggcgcct cccgagccga aggacgacca ggtgcaggat tggggcggtt
    17941 tcgccggcat cgggttgtcg ctgacggtgg cgtggctcgc cgggctgaac acccggcagc
    18001 gccggatccg cctttcggtg ctggaacagc gggccgccga cctcgaacgc gagcgggaca
    18061 cccaggccgc gctggccgtg gccgccgaac gcggccgcat cagccgcgag ctgcacgacg
    18121 tcgtcgcgca cgcgctttcg gtggtggtgt tgcaggccca aggcgcccaa gccgaactgg
    18181 agcggcggcc ggaacggacg cgggaggcac tggacgccat cgtcggcacc gggcggaccg
    18241 cgttggccga gatccggcgg ctgctcggcg cgctcggcca ggacgaaccg gattgggagc
    18301 cccagcccgg cgccgaacgc ctgccgcggc tggcggccga catccgtgcc gcgggcactc
    18361 cggtcgagtt ccgggtcgaa ggggaaccgc ggccacttcc gtccacagtg gacctcgcgg
    18421 cgtaccggat cgtgcaggag gcgctgacga acgtgctgaa acacgccggc ccggcggcgt
    18481 cggtgactat cgtgatgcgg tatgagcccg agacgctgga gatcgaagtg accgacgacg
    18541 gcaccgcggc ggaagagccg tccggcgccg ggcacggcct cgagggcatg cgggaacggg
    18601 tgaacgtcct gggcggcacc ttcgacgcgg gaccgcgtcc ggagcgcggc ttcgccgtcc
    18661 gcgcgaccct gccgacatga cgatccgggt ggtcatcgcc gacgaccagt cgctcgtgcg
    18721 caccggtctg cggatgatcc tggacaacgc cgacgacatc gacgtcgtcg gcgaggcggg
    18781 cgacggcgcg gaggccgtcg cgctggtggc ggacctcgat ccggacgtgg tgctcatgga
    18841 catccggatg cccgagatgg acggcgtcga ggccaccgcc gcgatcgccg cggcccaccg
    18901 ggcccgtgtc ttggtgctga ccacgttcga cctggacgag tacgtctacg ccgcgctccg
    18961 ggccggggcc agcggcttcc tgctcaagga cgcgctggcg ccggatctgc tcgccggcgt
    19021 ccgcgtggtc gcctccggcg aggccaccct cgcgcccacc gtcacccggc ggctgctcga
    19081 ccgcgtcgtc accggtctgc ccgcggcgcc gccggacgac cggctcgccc tgctcaccgg
    19141 gcgggaaaac gaggtgctgc ggcagctggc ccggggactg tcgaacgccg agatcgccga
    19201 gctgctgttc ctctcaccgg ggacggtgaa gacgcacgtc ggccgcatcc tcacgaaact
    19261 cggcctccgc gaccgcgtcc aggcggtcgt gttcgcctac gaatccgggc tgatcagccg
    19321 ctgaccgcgg cgggcgtacg ccagtgcttg ccgcggcggg gccgacggtg ctggccacgc
    19381 ctgccgaggt cgccgagggc ggccggcggc cgggcggcga actcctcggc cgtgatgccc
    19441 atccgcacca ggtacttgat ctcgccgcgc accacctcgg tgtcggccag cctgccctcc
    19501 tcgcggaagc cgaggccgcc gtgcagcgag agcgacgcga ggttgccgcc gtacacgctg
    19561 acctcgcatt tgcggaagcc gcgctgcccg aacatatgcg ccagcaggac ggtgatggcg
    19621 tccgtggcgt agccgcagcg ctggtgacgc ggggcgatcc cgatgccgta gccgaacttg
    19681 ccggtcgccg gatcggcgcc gatggtgcag accgagccga ccagcatccg gccgcgcacc
    19741 gtctcgatgc cgaagtggat gtcgtcgccc gcggaccccg aacggtgcga agcccaatgc
    19801 cggtgcccgc cgccgatcag cggcgtcgcc tcgcgggcca tgtcccggtc gaagcccatc
    19861 aggacgcggc ggtcccggag gccgacctcg cgcaaccgca ccttccgccc gacctgctcg
    19921 ggctccaggg cggagcggct caccgtgtcc ggccgcacgt gtgctcacga acgatcacaa
    19981 gcatgcctcg acgatatcgg tagccgaaac gcccgaaggc ccccacccgg tacggatgga
    20041 ggccttcggc gtgagagaaa gtcagatggc gacgacgcgc tgggcctgcg ggcccttctg
    20101 accttggccg atttcgaact cgacgcgctg accctcgtcc agggacttga agccggtgcc
    20161 ctgaatctcg gagtagtgca cgaaaacgtc cggtccgccg tcgtcctgag cgatgaagcc
    20221 gaagcccttt tcgccgttga accacttaac gctgccctga gccatacttt tttacctgct
    20281 cttcatagcg agtctgagcc cattcgatgc cccgatctcg ctgtccattg tcgcaggtct
    20341 tgcccgttcg cacacgctgc cgtcccgaac cgggtcattt ccccaggtca acatcgacct
    20401 tggcgagtcg gccggatcgt cggatcgccg attttcgacg tcgccggggt cggtgacgtc
    20461 cacccgcgtg gcggccgcct gcccgccgcc gctccgctgc tgcccgccga gcgcgggccg
    20521 cggtgccgcg cctgtccaca ggggcactgc acggcgactc cggtgggggt cgtgagtgaa
    20581 aaagagggtt agaacgatca ttgccactca cgacccccgc gaaagcgccc aaatcagaca
    20641 cttcgatggg ggccgtgtcc ctcgtggaca gcgacaggcc tactgggcgc acccgtccac
    20701 cgccaccttc cactggcacc gaattgccac tcacgacaaa cacggacggc cgttcagagt
    20761 tcgcccgccc gctcgtacag cttccgcacg ggctcggtga aggcggcacc gctcaggtcc
    20821 gtggtcacgc cgtcctcggt catcgtcccc cggctcgtga cgctgaagat cgtgcccttg
    20881 ccactggcgg ggtcgaagtt ccgcagccac gggccaccac tggagccacc ggccagatcg
    20941 caatcggtgt tccacgtcgt ggtgacagag ttcgcctcgc gcgtggcggg ccggacgcag
    21001 gagaacaacg cctcgccgcc cgccgcccgc gacacgggat agccgaacat ggtcgtgtcc
    21061 acagtggacg gcagttcctc gaacgagatg tcctgggtgc ccgcgacgtc cgcgacgtga
    21121 cggccgccga ccgggtccag cgcgatcacc gcgtcgtcgt ccgacccgct catcggcccc
    21181 gcgtacgtac tggaccaggc gaaagaccgt gccgggaaga ccccgtgcgg tgcggcgccg
    21241 cgatcgtagc ccgggacgaa cacgacgttg acgatcttga tcggccggtc gaaccggtcc
    21301 agtcccccgt tcacgcagtg cccggcggtg aacgcgacat ccttactgac actgggaacc
    21361 accgtcgccg tgcaggatcc gtcgacgccg ggctcggcgg tgaagaacaa ccgtccgacg
    21421 cccggcggga ccggcccctc ccatgcgcgg ccgatcttct ccgcgggcgg cagatcctcg
    21481 tcgcccaccc actgccgcat ccgctccggc gtccagtggg ccagggccgc cgcccggtcg
    21541 gcctcgctca ccacggtgac gacctggtcg tcggccgtgg ccggagcggc gacggcgacc
    21601 gtcgcggcac cgaaggcggc cgacagggcg gcgatccggc gaactgcgtg cttcaagtcc
    21661 atacgaaatg gacgttcctg ccgccgggaa ggttgttcac tcacccgtgc gtgtcgggct
    21721 ccgagccgat ccggtaggac acgggcctgc cttcttcgtc ccgcacctcg accggcttgc
    21781 cgtcggcgtc cacgattttg ccgtcgacga tcttgtcgcc gttttcgagc cgggagaagg
    21841 ctttcaggtc ggagtagtcg atcaccctgg tcgccgtcgc gaacaccgac ggatcgctgc
    21901 ccgccttggc gggcttgagg tggttgaaca acaggttcag caagacggcc gtgagcgcgg
    21961 cggagctgat ccccgagtgg aagatcgtgc cgacccacgc cgggaagtgg tgatagaact
    22021 ccggcgccgc gatcgggatc atgcccatcc cgaccgacgc cgcgacgatc accaggttca
    22081 tgttcccgtt gtagtccact ttggacaatg tcttgatacc ggacgcggcg accgtgccga
    22141 acagcacgag accggcaccg cccaataccg ggtacgggat cgccgccacc acgcggccga
    22201 gcaccgggag catgccgagg atcagcagga tcacgccgcc cgcggtcacc acgaaccggc
    22261 tcctgatccc ggtgatcgcg acgagaccga cgttctgggc gaacgcgctc tgcatgaacc
    22321 cgttgaacac cggcgcgatc gccgaggacg ccatgtcggc gcgcagcccg tcgccgatcc
    22381 ggcgtttgcc gacccgcgtg tcgacgatct cgccgaccgc gaggatgtcg gccgtggtct
    22441 ccgtgagggt caccagcacg acgatgaaca tcgacacgat cgcggcgacg tcgaaggtcg
    22501 gcatcccgaa ggcgaacggg gtcggtaccg cgaagatcgg g
//
