LOCUS       NZ_LT629789            22859 bp    DNA     circular CON 13-MAY-2024
DEFINITION  Amycolatopsis keratiniphila strain FH 1893 chromosome I.
ACCESSION   NZ_LT629789
VERSION     NZ_LT629789.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900105855.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 02:01:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,886
            CDSs (total)                      :: 8,813
            Genes (coding)                    :: 8,742
            CDSs (with protein)               :: 8,742
            Genes (RNA)                       :: 73
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 26 of 71
            Pseudo Genes (incomplete)         :: 51 of 71
            Pseudo Genes (internal stop)      :: 1 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:07:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1851437
            Orig. end                         :: 1874296
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT629789.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22859
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="8"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22859
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22859
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12859](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12859)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            5..2338
                     /locus_tag="BLU53_RS08135"
                     /old_locus_tag="SAMN04489733_1680"
     CDS             5..2338
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334474.1"
                     /locus_tag="BLU53_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1680"
                     /product="chitobiase/beta-hexosaminidase C-terminal
                     domain-containing protein"
                     /protein_id="WP_072027051.1"
                     /transl_table=11
                     /translation="MNRIFVQPKRRKGVRGALALGLSALLIAAGLGGATAAAADYSQNA
                     ASLNATQAQFSFTPATPARYVDIHYTGVPGVGQQNVRMTDNGGTWRHTVGSLSAGTVLD
                     YWFTYEKNGPQYDTPHFTYTHGGSGTTVASPTFDPPGGSYPSARSVTLTSATAGATIRY
                     TVDGSTPTASSTVYTGPITVSASSTISAIALKAGSANSPVSSATYTIGSTQGTCPAQAE
                     VPDFGPNVRIFDPGMSAASIQSRLDADFNAQKDTLTAQFTERRYAHLFKPGVYNGIHDN
                     VGYYTSVAGLGQNPGDVVINGDVTVDAFNESDKGVALQNFWRSAENLAVVPSSGSTRWA
                     VAQAAPFRRMDIRGGLQLYPASYGFASGGYTADTKVSGQAASISQQQWYTRDSSYGSWD
                     GGVWNMVFSGTSGAPANTFPNPPETTLGTTPVSRDVPYLYLDGSGKYRVFLPSLRTNAS
                     GPSWANGGTQGSSLPMSQFYVVKAGDTASSINNALSQGCNLFFTPGVYHLNQTLNVTRA
                     NTVVLGVGYPTLVPDNGVDAMKVADVDGVRLKGLLFDAGTTNSQSLLTVGQAGSTANHA
                     ANPTTLQDVFFRIGGQIAGKATNSLIVNSRDTIIDHIWAWRADHGNAGTYGWTINTGDT
                     GVVVNGDNVLATGLFVEHYQKYQVIWNGQNGRTIFFQNEIPYDVPDQAGWRSPNGLNGY
                     AAYKVGDNVTTHEAWGLGSYCFFNDNPSVNLYHAFEVPNRSGVRFHNLVTVSLNYKGTI
                     THVINDAGAVTPPDTRPSNLVSYP"
     gene            2520..3845
                     /locus_tag="BLU53_RS08140"
                     /old_locus_tag="SAMN04489733_1681"
     CDS             2520..3845
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012398.4"
                     /locus_tag="BLU53_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1681"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_076153277.1"
                     /sec_met_domain="Aldedh (E-value: 3.3e-82, bitscore: 275.5,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARLESMTSSDASAVVEELRALFRSGVTKPVEWRRTQLTGLRKLL
                     SEQADVFLKALYADLRKNTAEAKRAEIALVRSEIDHTLENLDSWLSPEPAGLPYPLRPA
                     DGRVVREPLGVALIIGPWNYPLQLVLAPLVGALAAGNCAVVKPSELSPNTSAAIAEHLP
                     NYVEGVRVVEGAVPETTALLEQKFDTIFYTGNGTVGRIVMAAAAKHLTPVTLELGGKSP
                     AIVEPGADLAVTAQRLAYGKFANAGQTCVAPDYVLAIGDTGPKLAEHLAETVKAMFGED
                     PATSEAYGRIISTRHHDRLTALLDNGTVVVGGQADRDEKYIAPTVLTDVSPDAPVMRDE
                     IFGPILPIIDVPDVDAALEFVNERDKPLALYAFTESEETKRRIETETSSGGLVFGAAII
                     HLVAPELPFGGVGESGMGRYHGRYSIENFSHVKAVLDKPLAG"
     gene            complement(3847..4515)
                     /locus_tag="BLU53_RS08145"
                     /old_locus_tag="SAMN04489733_1682"
     CDS             complement(3847..4515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334472.1"
                     /locus_tag="BLU53_RS08145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1682"
                     /product="hypothetical protein"
                     /protein_id="WP_072027053.1"
                     /transl_table=11
                     /translation="MAERDAPQAGPAGRLFRAGFHALSALRGARAFHPNGLLLKGELHA
                     LRSDEIALPPEPVRVTVRMSKGAGLPGRVPDALGLAVRIPAADGAPWDLTLTTSAGRVL
                     PRPARSWTAGRYSSLLPYRTNDELVWLSARAETPRHAEASLDALSRLVKEGPVTYLLET
                     VRANGHRKSCATLTLHEVDEDASRPAFDPMLNAPPGWELRPRWLTGLRERAYEGSREGR
                     "
     gene            4682..5137
                     /locus_tag="BLU53_RS08150"
                     /old_locus_tag="SAMN04489733_1683"
     CDS             4682..5137
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334471.1"
                     /locus_tag="BLU53_RS08150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1683"
                     /product="DUF4383 domain-containing protein"
                     /protein_id="WP_063273915.1"
                     /transl_table=11
                     /translation="MTASPATVRRAPRQLIALGVGAVFLLVGILGFIPGITTNYEQLSG
                     AGHESGALLLGVFQVSILHNIVHLAFGVAGILLARTVSGAKAFLVGGGVVYLVLWLYGL
                     LIDHGSAANFVPVNSADNWLHLGLAVGMIALGLIPLSGSKAPIADSR"
     misc_feature    complement(4725..4740)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.68"
                     /tool="antismash"
     gene            5170..6051
                     /locus_tag="BLU53_RS08155"
                     /old_locus_tag="SAMN04489733_1684"
     CDS             5170..6051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334470.1"
                     /locus_tag="BLU53_RS08155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1684"
                     /product="manganese catalase family protein"
                     /protein_id="WP_072027054.1"
                     /transl_table=11
                     /translation="MFRHTKSLQFEAKPEKPDALYARKLQELIGGAYGEMTVTMQYLFQ
                     GWNCRIEGKYKDLIMDTATEEIGHVEMLATMVARLLEGAPATTVAEAAKDPATAAILGG
                     MDPQQAIISGGGATPSDSQGYPWNGRYVVASGNLLADFRANAAAEAQGRLQTARLYNMT
                     DDPGVKAMLQFNLARDTVHQKQWLAAIEELKADGLESDIAPTALFDEENQDHNNTVWHL
                     SDGPDGAKGGWSFGEDGIEYLMDPEPLGGPGTAPKPDPALYGTYAPLQDAVGTIKGKAK
                     DAKKKATKSRKS"
     gene            complement(6349..6564)
                     /locus_tag="BLU53_RS08160"
                     /old_locus_tag="SAMN04489733_1685"
     CDS             complement(6349..6564)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334469.1"
                     /locus_tag="BLU53_RS08160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1685"
                     /product="hypothetical protein"
                     /protein_id="WP_063273917.1"
                     /transl_table=11
                     /translation="MTLPDVPVGTRVVVRYRIEGGFTDALGYLRSRDETECTVETKRGL
                     ATIRLADIVLAKTVPPPPAPRRPREW"
     gene            complement(6561..6800)
                     /locus_tag="BLU53_RS08165"
                     /old_locus_tag="SAMN04489733_1686"
     CDS             complement(6561..6800)
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334468.1"
                     /locus_tag="BLU53_RS08165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1686"
                     /product="glutaredoxin domain-containing protein"
                     /protein_id="WP_016334468.1"
                     /transl_table=11
                     /translation="MSDLIVYGAGWCPDVKRSRALLDSKGVEYAYIDVEADSGAEETVR
                     ALQNGERRIPTIVWPDGTHLVEPSDDELTAHLNR"
     CDS_motif       complement(6774..6800)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDLIVYGA"
                     /locus_tag="BLU53_RS08165_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6561..6773)
                     /prepeptide="core"
                     /locus_tag="BLU53_RS08165_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="7675.4"
                     /monoisotopic_mass="7670.9"
                     /core_sequence="GWCPDVKRSRALLDSKGVEYAYIDVEADSGAEETVRALQNGER
                     RIPTIVWPDGTHLVEPSDDELTAHLNR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDLIVYGA"
                     /leader_location="[6773:6800](-)"
                     /alternative_weights="7693.4"
                     /alternative_weights="7711.4"
                     /alternative_weights="7729.4"
                     /alternative_weights="7747.4"
                     /alternative_weights="7765.5"
                     /alternative_weights="7783.5"
                     /alternative_weights="7801.5"
     gene            complement(6804..9692)
                     /locus_tag="BLU53_RS08170"
                     /old_locus_tag="SAMN04489733_1687"
     CDS             complement(6804..9692)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029579.1"
                     /locus_tag="BLU53_RS08170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1687"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_072027055.1"
                     /transl_table=11
                     /translation="MGIRSSRMIGRDAELAELSGALDRAIAGRGGAIFLVGEGGVGKSR
                     LAIEAASRAVAADVPVLQGRASSIGPLVPFRPLTQALLSHFRGGGPPEATELDPFVPVL
                     AQLIPDWSRGDRPRESGSLMVLAEAVFRLLAVTSRDRGALLVLDDLQDADAETLFILEY
                     LVDNLPAAHTLFVGTLRSEPSDALRLATSGAQRMSCAVVELGRLGLADTHALAAACLET
                     EPERLPSAATELLWRNSAGLPFIVEELLHGMVNDGLLVEGRDGWRVIGELRARVPAALV
                     TSIGVRMEQLGEQAGELLSVAAIIGRRFPLTVVQKVTGTNDRTLHNHLGAAVSANLVTT
                     DEMTPGWYAFRHPLTAEALLARQSPARKAELARQTADAVEELYPGLPGDLCALVASLRL
                     TALDERAAGRLFAETGRRALDAGAADSAVTMLTKALDLLAGADAGDRAEVLETLVHALG
                     QTGQFDRAVELSAAFGEIGTLERAAKLRTQLAWAAYIAGRHDECLGQIERARAPLGSAI
                     SPAQQAALDAVEANLWLDVPGRTGTAERLARQAWKVAEATEQPFVVCQALQVLGMLALS
                     RDLSESEHYMQLARRTAEDNHLHHLRTQALVRLGGHRVLMNGDEQTLLLARADAQRTGS
                     ITLHCAVDSVRTMHAILRCDFGTAHTLLAENLAVLGRLRLTALLQYAHMTRAMSAGHRA
                     DRPAMEQALDDFRESGGENAQEMVLSIGLARVFCSLLEEDFDRARRELGQVIELEDRRP
                     SRFHLAGQHGLRTLVDTLGGAPCPDGGSAVSGMRWNRQFVEFAQAVEHGRRGDAAEAER
                     AVASALETSAPYPLARHLGLRLIAEPAAADGWGDPAGWLKAAEEYFHGRDIQAVAAACR
                     TLLRKLGAPVRQRRSGVDRVPGDLRAAGVTVREYEVLVLLAERMGNKDIGARLHISPRT
                     VEKHVASLLAKTGLADRAALAEHAAGPRPGML"
     gene            complement(9782..9976)
                     /locus_tag="BLU53_RS08175"
                     /old_locus_tag="SAMN04489733_1688"
     CDS             complement(9782..9976)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029580.1"
                     /locus_tag="BLU53_RS08175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1688"
                     /product="hypothetical protein"
                     /protein_id="WP_016334466.1"
                     /transl_table=11
                     /translation="MYERDLPATEDVLGAVNLPRALEVGSRNHALAGSKPRLSANPLAT
                     LSTDTGSPSVVSVFTGGWI"
     gene            complement(10001..12859)
                     /locus_tag="BLU53_RS08180"
                     /old_locus_tag="SAMN04489733_1689"
     CDS             complement(10001..12859)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="BLU53_RS08180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1689"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_228708273.1"
                     /sec_met_domain="DUF4135 (E-value: 6.1e-99, bitscore:
                     330.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.3e-14, bitscore:
                     50.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPQPSATSLPPRWWEHGRTPRERSADKPLWADFAEHAITTLLPE
                     RPPVGDWRAAFAGVFRSLVDAASRDAVPDDLPGADVDALRQGFAANLDQHLLNLSVRTL
                     VLELHRARKAGTLEGATPEERFSDFVRRQSTPAGLTRLFGEYPVLARLLAQACLYAAEA
                     HAETLARFSADAALLPCTVVDGELGTLVEVAGGFGDSHAGGRSVKLLRFSSGAKVIYKP
                     RPLILHERFTDVVEQLNKRLPGLELRTADALPRDGYGWLRFVEHRPCADLGDVDRFYRR
                     QGILLALLHALDATDVHYENIIACGDQPVLIDIETLFQPSPPVPPEGDPAAAMLARSVQ
                     RTLLLPQLFAGEHGAVDISGLAGRGGKLPTDRVDWADAGTDRMRLVRVPGELAGSHNLP
                     RLDGRDVAPAEHSAALLAGFRLGYDAISSGRDELAELLRRCAEDPIRVLIRPTNFYSRL
                     LDETTHPDLLRDAADRDHAFDLLEDDSVREEKLLRLVPHERDDLWAGDVPMFTSNPGST
                     SLLDSRGDSVEGVVERPSLDTVLAKVADMDPLDQRDQEWLITATLAISTAADGHHGDGE
                     TAETAVPNQAPDAERLLVTACGIADQIVASAFSDEHRSNWLGIELVDDRYWTVLPMGAG
                     LGEGYCGVALFLAQLAELTGIARYRDLAAYAISPLPGLFATLRADRELAATAGCGGLLG
                     LGGVAYTIARLSTLVGLPAGDLIEQAVDLMPEATAETPSGFTTGLAGGVASMRSVYVQT
                     GLETALARADRYATQLLERERPVEKSFARGSAGIDWVLRAHERPGEEPPGKADDRTEST
                     GGWCDGLTGDALGTAAHLPDPEYARDLDRTIGRLTDRAPLKDLSLCHGESGVLDVLCVL
                     AENGHTGAAAAVRRRTGHLLAAIDQRGARCGTPGAVPSPGLLSGLAGIGYGLLRLGFGD
                     RVPSALLLRPDRPHPAATVFRR"
     gene            13117..14349
                     /locus_tag="BLU53_RS08185"
                     /old_locus_tag="SAMN04489733_1690"
     CDS             13117..14349
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334464.1"
                     /locus_tag="BLU53_RS08185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1690"
                     /product="acetyl-CoA hydrolase/transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_063273920.1"
                     /transl_table=11
                     /translation="MRVLSESQLGSVLAGVPATCPRVVVSGNFATPMRALKVLDAALAE
                     YRLFALNAQAGMPDREGVLLETPFVGAGMRGRPGLRYFPSRLSLVPQLLKHSLPPDVVL
                     LHTSAPVDGVVSLGTEVNILPAAIEAVRARGGLVIAQLNPEMPFTYGDGLVPVDEIDYG
                     IEVVEALLSPVPRPVGETARTIGERVAGLVEDGATLQLGIGGIPDATLAAVTGRRGLAI
                     WSEMFSDGVLALDRAGALDPAEPVTASFVFGSADLYRWLDRNPRIRLLRTEKTNDPAVI
                     ARQRGLVSVNSALEVDLYAQANASRVRGAIYSGFGGQTDFVVGALHSPGGRAIIALPSW
                     HPKADVSTVVPRLTGPVTSFQHSFVVSEHGVATIWGNDASEQARQIVGQVAHPSAREEL
                     VARGRELGFAL"
     gene            complement(14987..15937)
                     /locus_tag="BLU53_RS08190"
                     /old_locus_tag="SAMN04489733_1692"
     CDS             complement(14987..15937)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634733.1"
                     /locus_tag="BLU53_RS08190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1692"
                     /product="aldo/keto reductase"
                     /protein_id="WP_072030903.1"
                     /transl_table=11
                     /translation="MLARHPLGNSGLTVSSLCLGGNVFGWTADGRESFEVLDAYVAGGG
                     NFVDTADSYMFHFPGNEAGQSETIIGEWLASRRGRDDVVVATKVGDHPRYKGLAPSNIK
                     AAAEESLRRLGTDRIDLYYTHFDDESVPVEDIITALDDLVKAGKVRAIAASNIGPERLS
                     ASLAFSDREGLARYVALQPPYNLVSRDTYEGDLRNVARSEGLACIPYFALASGFLTGKY
                     RPGKPVDSVRDLPGLAGGYADTERGTKVLAALEKIASAKGVEMATVALAWVARQPTVLA
                     PIASARTLEQLPSLLAFEELRLSDAELQALTAASA"
     gene            complement(16031..17140)
                     /locus_tag="BLU53_RS08195"
                     /old_locus_tag="SAMN04489733_1693"
     CDS             complement(16031..17140)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157434.1"
                     /locus_tag="BLU53_RS08195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1693"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_072027056.1"
                     /transl_table=11
                     /translation="MQRKLSRPSLRIRLVAALTTAGLIATTGTALADSGADRKVVQEAL
                     DQLTTSGGALGVQARVTDGHQRFTARSGKAELGSNRPVPENGRFRVGSITKTFVSTVLL
                     QLEGEGRLDLDAPVVRYLPGLIDGRITVRQVLQHTSGLYNYTDALPLDPAEFEKIRYKH
                     WTPRELLKISTGRPLDFDPGTRWSYSNTNYVVAGLLVERLTGKPYEKAVEQRILKPLRL
                     HDTEVPGDDVGISGPHAHGYVSVAGKPVDITRLNPSVAWAAGEIISTTRDLDTFGVALA
                     GGRLLEPAQQKEISKTTAVSPEYGLGLQVQTLPCGTRVWGHGGGIPGYSSQLLTTPDTH
                     KRLELSATSAPTGGDSNPAFVKLLTEVFC"
     misc_feature    complement(17290..17306)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     misc_feature    17295..17309
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            17375..18955
                     /locus_tag="BLU53_RS08200"
                     /old_locus_tag="SAMN04489733_1694"
     CDS             17375..18955
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013661.4"
                     /locus_tag="BLU53_RS08200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1694"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_083715255.1"
                     /transl_table=11
                     /translation="MKRSLATSLAVVGVLTTSLIPVTASDAALLARPDYPAARWVAADP
                     GNWGSRNGDTITGIALHTFDPVPPAVPDYDSTIRFFANPNAAQTSAHYVIRSRDGDITQ
                     MVQNQDRANHLRGHNGNTIGIEHEATSREEKWYTDIMMRSSAALVRDLCERYLIPRTGS
                     SDPDGQSGGIRGHNQFSGHEGNSDPGRFWYERHDAYLQKVRGGKRDAAVPFGGQYQIFQ
                     RQRDHSVHQRVWDGSAWRGWADLGGSFAGEPAAVAFGRQMHVFGIDRATRQLRTRYWDP
                     SGGWSNWAEPGGTPARLRGNPSAVVIGQNLHVFARGENNQVYEARWSDGAWRWTNLGGT
                     VVGDPAALDFGGQAQVYALGSDQRLYSNVLGGSGWGGWAKSGEPGARLNGTPSVIRFGG
                     QAQAFVQGLNGNVYQAVWNREGGWTWHNLGGAIFGDPSATVVGSTVRVTALGTDNQLWT
                     DSWSANGWTGWQKAAGGPAGGLTGTPTAMAFGNQLQVTVQGLNGRAHQAAWQPGSNWWW
                     ADLGGTAAN"
     misc_feature    18978..18992
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            19087..20061
                     /locus_tag="BLU53_RS08205"
                     /old_locus_tag="SAMN04489733_1695"
     CDS             19087..20061
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="BLU53_RS08205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1695"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_072027058.1"
                     /transl_table=11
                     /translation="MLRIHFTDADISRITIAEDVDASWETLFSLHLLQEPDEILSFDHW
                     RRRIRAELPAWIPLLLELAPPRGYSADFLTPGRGDADSDTVIDRIMSTPRRRLRDDVAC
                     LVDRRPPTPWTRKLANGDVTALRQLGTALDRYYQRAVAPYRGRLRAHVEADRSRRGKAL
                     LTGGVDRLLATLHPRVEWRPPVLRVLDYVDQDLHLDGRGLVLLPSHFCRHHPVTLKDAD
                     LPPVLAYPVSSSFAWLTPDRPATQDPVTSLLGRTRAATLRASTTAVTTTDLARRIGLSP
                     PSASKHARVLREAGLITTRRDGGAVVHQVSGLGVAVLNGELPA"
     misc_feature    19183..19185
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20130..21452
                     /locus_tag="BLU53_RS08210"
                     /old_locus_tag="SAMN04489733_1696"
     CDS             20130..21452
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005164792.1"
                     /locus_tag="BLU53_RS08210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1696"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_016334451.1"
                     /transl_table=11
                     /translation="MTEPNLIEAAAEEAVTLTSELIRIDTTNTGDPDTLVGERAAAEYV
                     AEKLTDAGYEITYVESGGKNRHNVIVRLPGADPSRGALLIHGHLDAVPADASEWSVHPF
                     SGAIQDDYVWGRGAVDMKDMCAMTLALARHYKINGIVPPRDLVFAFLADEEAGGKYGAQ
                     WLVENRPELFEGVTEAISEVGGFSITLKDNVRAYLIETAEKGIRWMKLRVRGTAGHGSM
                     IHRDNAVTKLSEAVARLGNHRFPLVMTDSVREFLDGVTEITGWDFPEDDIEGSVAKLGN
                     ISRMIGATLRDTANPTMLTAGYKSNVIPSVAEASVDCRILPGRLEAFNAELDEILGPDI
                     EKEWMELPPVETTFDGALVDAMTNAVLAEDPGARTLPYMLSGGTDAKSFQSLGIRNFGF
                     APLQLPADLDFSALFHGVDERVPVDALKFGVRVLDRFLRSA"
     gene            21452..22255
                     /locus_tag="BLU53_RS08215"
                     /old_locus_tag="SAMN04489733_1697"
     CDS             21452..22255
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-186). E-value:
                     2.8e-20. Score: 64.9. Matches aSDomain:
                     nrpspksdomains_BLU53_RS08215_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334450.1"
                     /locus_tag="BLU53_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04489733_1697"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_072027059.1"
                     /sec_met_domain="PF00561 (E-value: 2.9e-14, bitscore: 52.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-17, bitscore:
                     64.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGLLAADGTPLHFERWGDPSAPVTVVLLHGYALDRRSWRAIAPV
                     LAEAAEKPVAVLAYDQRGHGESGEVRAASATMGHLADDLAEVLEKVIPDGKVVLVGHDM
                     GGLAILSLAQRHPEVFAARVAGIGLLAMSAGGVTPDAIWPNALGKLGRDLEMVFGTKLI
                     GLVREHTSKAVTAGLRWWLFGDDPVPADVELTVRMIRGNWPQTVSAFRPALDAYTRESA
                     LSQVGAVRNGTSVVLPGVGHVVPLEAAPQVVPRLLALANRAHRQD"
     aSDomain        21524..22009
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU53_RS08215_Abhydrolase_1.1"
                     /evalue="2.80E-20"
                     /label="BLU53_RS08215_Abhydrolase_1.1"
                     /locus_tag="BLU53_RS08215"
                     /protein_end="186"
                     /protein_start="24"
                     /score="64.9"
                     /tool="antismash"
                     /translation="TVVLLHGYALDRRSWRAIAPVLAEAAEKPVAVLAYDQRGHGESGE
                     VRAASATMGHLADDLAEVLEKVIPDGKVVLVGHDMGGLAILSLAQRHPEVFAARVAGIG
                     LLAMSAGGVTPDAIWPNALGKLGRDLEMVFGTKLIGLVREHTSKAVTAGLRWWLFGDD"
     misc_feature    22257..22270
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.32"
                     /tool="antismash"
ORIGIN
        1 cgacgtgaat cggatctttg tgcagcccaa gcgccggaaa ggggtccggg gcgcgctcgc
       61 cctcggcctt tccgcgctcc tgatcgcggc agggctcggc ggtgccaccg ccgcggccgc
      121 cgactacagc cagaacgccg cgtccttgaa tgcgacccag gcgcagttct ccttcacgcc
      181 ggcgactccg gcgcgttacg tcgacatcca ctacaccggc gttccgggtg tggggcagca
      241 gaacgtccgc atgaccgaca acggaggcac gtggcggcac accgtcggct cgctgtcggc
      301 gggcacggtg ctcgactact ggttcaccta cgagaagaac gggccgcaat acgacacccc
      361 gcacttcacg tacacccacg gcggcagcgg cacgaccgtc gcgtcgccga ccttcgatcc
      421 gccaggcggc agttacccga gcgcccgttc agtgaccctg acgagtgcga ccgccggagc
      481 gaccatccgg tacacagtgg acggttccac gccgacggcg tcgtccactg tgtacaccgg
      541 gccgatcacg gtctccgcgt cctcgacgat ctccgcgatc gcgctgaagg ccggctcggc
      601 gaattccccg gtgtcctcgg cgacctacac gatcggatcg acacagggga cctgcccggc
      661 tcaggccgag gtcccggact tcggcccgaa cgtgcggatc ttcgaccccg gtatgtccgc
      721 ggcgtcgatc cagtcccggc tcgacgcgga cttcaacgcg cagaaggaca ccctgaccgc
      781 gcagttcacc gagcgccggt acgcgcacct gttcaagccc ggtgtgtaca acggcatcca
      841 cgacaacgtc ggctactaca cgtcggtcgc gggtctcggg cagaacccgg gcgacgtggt
      901 gatcaacggt gacgtcaccg tcgacgcgtt caacgagtcg gacaagggcg tggcgctgca
      961 gaacttctgg cgctcggcgg agaacctcgc cgtcgtcccg agcagcggct cgacccgctg
     1021 ggccgtcgcg caggccgcgc cgttccgccg gatggacatc cgtggcgggc tacagctcta
     1081 tccggccagc tacggcttcg cgagcggcgg ctacaccgcc gacaccaagg tctccggtca
     1141 ggccgcgtcg atctcgcagc agcagtggta cacccgggac agcagctacg gcagctggga
     1201 cggcggcgtc tggaacatgg tcttctccgg cacgagcggc gctcccgcga acaccttccc
     1261 gaacccgccg gagacgacgc tcggcaccac gccggtgtcc cgcgacgtcc cgtatctcta
     1321 cctcgacggc tccggcaagt accgcgtgtt cctgccttcc ctgcgcacca acgcctccgg
     1381 gccgagctgg gccaacggcg gcacccaggg ttcctcgctg ccgatgagcc agttctacgt
     1441 cgtgaaggcg ggggacacgg cgtcgtcgat caacaacgcc ctctcccagg gctgcaacct
     1501 gttcttcacg ccgggcgtct atcacctgaa ccagacgctc aacgtgacca gggcgaacac
     1561 cgtcgtgctc ggtgtcggct acccgacgct ggtgccggac aacggcgtcg acgccatgaa
     1621 ggtcgccgac gtggacggcg tccggctgaa gggcctgctg ttcgatgccg gaacgaccaa
     1681 ttcgcagtcg ctgctcacgg tcggccaggc gggctcgacc gcgaaccacg cggcgaaccc
     1741 gacgaccttg caggacgtgt tcttccggat cggcggtcag atcgctggga aggcgacgaa
     1801 cagcctgatc gtcaacagcc gtgacacgat catcgaccac atctgggcct ggcgggccga
     1861 ccacggcaac gcgggcacct acggctggac gatcaacacc ggcgacaccg gcgtggtcgt
     1921 caacggcgac aacgtgctgg cgaccggcct gttcgtcgag cactaccaga agtaccaggt
     1981 gatctggaac ggccagaacg gcaggacgat cttcttccag aacgagatcc cgtacgacgt
     2041 cccggaccag gcgggctgga ggagtcccaa cgggctcaac ggctacgccg cctacaaggt
     2101 gggggacaac gtgaccacgc acgaggcgtg gggcctgggc agctactgct tcttcaacga
     2161 caacccgtcg gtgaacctgt atcacgcgtt cgaggtgccg aaccgctccg gcgtccggtt
     2221 ccacaatctg gtgaccgtgt cgttgaatta caaggggacc atcacccacg tgatcaacga
     2281 cgccggggcg gtgacgccgc cggacacgcg gccgagcaac ctggtgagct acccgtaacg
     2341 ccgggcggtc ggtacagctg ctcgtgagtg gcgtttcggg ttctaacccg aaacgccact
     2401 cacgacccgt atccagccgg gctgaaggct cctttcgctg cgtctgatgc gacgaaggga
     2461 gccttcagct tctcgtataa cgctctatac cacgcaacgt tgggcatcag ccacggtcca
     2521 tggctaggct cgaatccatg accagcagcg atgcctccgc cgtcgtcgaa gaactacgcg
     2581 cgctcttccg ttccggtgtc acgaagccgg tggagtggcg gcgaacgcag ctcaccggcc
     2641 tgcggaagct cctgtcggag caggccgacg tcttcctcaa ggcgctctac gccgatctgc
     2701 gcaagaacac cgccgaggcg aagcgcgcgg agatcgcgct cgtgcggagc gaaatcgacc
     2761 acacgctgga gaatctcgac tcctggctga gcccggagcc cgccggcctg ccgtacccgc
     2821 tgcgaccggc cgacggccgt gtcgttcgtg agccgctcgg ggtcgcgctg atcatcgggc
     2881 cgtggaacta cccgctgcag ctggtgctcg caccgctggt cggggcgctg gcggcgggca
     2941 actgcgcggt cgtgaagccg agtgagctgt ccccgaacac ctcggccgcg atcgcggagc
     3001 atctgccgaa ctacgtcgag ggtgtccgtg tcgtcgaagg cgcggtcccc gagacgacgg
     3061 cgttgctgga gcagaagttc gacaccatct tctacaccgg caacgggacg gtcggccgga
     3121 tcgtcatggc cgcggcggcg aagcatctca cgccggtcac gctggaactg ggcgggaaga
     3181 gccccgcgat cgtcgagccg ggggcggatc tcgccgtgac cgcccagcgg ctggcctacg
     3241 gcaagttcgc caacgccggc cagacctgcg tcgcgcccga ctacgtcctc gcgatcggcg
     3301 acaccggccc gaaactggcg gaacacctgg ccgagaccgt caaagcgatg ttcggcgaag
     3361 acccggccac cagcgaggct tacggccgca tcatctcgac ccggcaccac gaccggctca
     3421 ccgccttgct ggacaacgga accgtggtcg tcggcggcca ggccgaccgc gacgagaagt
     3481 acatcgcgcc gaccgtgctc acggacgtct cgccggacgc cccggtgatg cgggacgaga
     3541 tcttcgggcc gatcctgccg atcatcgacg tgcccgacgt cgacgcggcg ctggagttcg
     3601 tcaacgaacg cgacaagcct ctggcgctgt acgccttcac cgaatcggag gaaacgaagc
     3661 gcaggatcga gacggagacc tcgtcgggcg ggctggtgtt cggcgcggcg atcatccacc
     3721 tcgtggcgcc ggaactgccg ttcggcggcg tgggggagag cgggatgggc cgctatcacg
     3781 ggcgctactc gatcgagaac ttcagccacg tgaaggcggt gttggacaag ccgctcgcgg
     3841 gatgagtcag cggccctcgc ggctgccctc gtaggcgcgc tcgcgtaggc cggtgagcca
     3901 gcggggccgc agttcccagc ccggcggagc gttcagcatc ggatcgaagg ccggtcgtga
     3961 ggcgtcttcg tccacctcgt ggagggtcag cgtcgcgcag gacttccgat ggccgttcgc
     4021 gcggacggtt tcgaggagat aggtcaccgg cccttccttg accagccggc tcagggcgtc
     4081 cagcgacgct tcggcgtgcc gtggtgtttc cgcgcgggcc gacagccaga ccagttcgtc
     4141 gttcgtgcgg taaggcagca atgagctgta acggccggcg gtccaggatc gcgccggccg
     4201 cggcagcacg cggccggcgg aagtggtcag agtgaggtcc cacggggcgc cgtccgcggc
     4261 ggggatccgg acggcgagtc caagcgcgtc cggcacgcgc ccgggaagac cggccccttt
     4321 ggacatgcgc acggtgacgc gcaccggctc cggcggaagt gcgatctcgt cgctcctcaa
     4381 ggcgtgaagt tcacctttga gcagtaggcc gttcgggtgg aacgctcgcg cgccacggag
     4441 cgcggagagg gcgtggaaac cggcccggaa aagcctgccg gccggccctg cctgcggtgc
     4501 gtcgcgctcg gccacgattt ccgcctcctc gtcatgtgag tgctccgcgc tggctacccc
     4561 ggcagcaccg gattacacgg gaattcccgc gaattcgaaa tcgccgattc cccggtgtga
     4621 ccggctccgg cgcgggtact cgaccttccg gaagctcatt ccacctggat cggaggaaat
     4681 catgactgca tcgccggcca ccgttcggcg ggctccgcgc cagctcatcg ccctcggcgt
     4741 gggcgcggtc ttcctgctcg tcggcattct cggcttcatc cccggcatca ccacgaacta
     4801 cgagcagctg agcggtgccg ggcacgagtc cggcgcgctg ctgctgggcg tgttccaggt
     4861 gtcgatcctg cacaacatcg tccatctcgc gttcggtgtg gcgggcatcc tgctggcccg
     4921 gacggtgagc ggcgcgaagg cgttcctcgt cggcggcggg gtggtgtatc tcgtgctgtg
     4981 gctgtacgga ctgctgatcg accacgggtc ggcggcgaat ttcgtgccgg tcaacagcgc
     5041 cgacaactgg ctgcacctcg ggctcgccgt cgggatgatc gcgctcgggc tcattccgct
     5101 ctccggctcg aaggcgccga tagccgactc gcgctgatcc gttcgttccc cattattcgg
     5161 aggtaatcag tgttccgtca caccaaatcg ctccagttcg aggccaaacc ggaaaagccg
     5221 gacgccttgt acgcccgtaa gctccaggaa ctcatcggcg gcgcctacgg ggaaatgacc
     5281 gtcaccatgc agtacctctt ccagggctgg aattgccgga tcgagggcaa gtacaaggat
     5341 ttgatcatgg atacggcgac cgaggagatc gggcacgtcg agatgctcgc gaccatggtc
     5401 gcccgcctgc tggaaggggc acccgccacc acggtggcag aggcggcgaa ggatccggcc
     5461 accgcggcga tcctgggcgg gatggatccc cagcaggcga tcatctccgg cggcggcgcg
     5521 acgccgagcg acagccaggg ctacccctgg aacggccgct acgtcgtggc gtcgggcaac
     5581 ctgctggccg atttccgggc gaacgccgcg gccgaggcac agggccggtt gcagacggcc
     5641 cggctgtaca acatgaccga cgaccctggc gtgaaggcga tgctgcagtt caacctcgcc
     5701 cgcgacacgg tgcaccagaa gcagtggctc gccgcgatcg aggaactcaa ggccgacggc
     5761 ctggaaagcg acatcgcgcc gacggcgttg ttcgacgagg agaaccagga ccacaacaac
     5821 accgtgtggc atctgtccga cgggccggac ggcgcgaagg gcggctggag cttcggcgaa
     5881 gacgggatcg aatacctgat ggacccggag ccgctcggcg gtccgggcac cgctccgaaa
     5941 cccgatcccg cgctgtacgg cacgtacgcg ccgctgcagg acgccgtcgg gacgatcaag
     6001 gggaaggcga aggacgcgaa gaagaaggcc acgaagtcac ggaagagcta gcccgactcg
     6061 tgagtgggtg tcttggctac ccatcgggcc cggccacgac caacgttgcg aaagccactt
     6121 tcgcaacgtt gaaggttgcg aaagtggctt tcgcaacccc tcgggtcaag gccggcaccc
     6181 agcgggaccg gcgagtcgcc tagcccagag cgggccacgc gtgatcagac ggacgacaca
     6241 ctcacggcga agctttcgcc gtgagccgtc cgtctgatca cgcgtgtcgt ccgtccgatc
     6301 acgcgagatc gccagtaggt accaggacac ggttggctct aaccgtcttt accactcacg
     6361 aggcctgcgc ggagccggag gcggcgggac cgtcttcgcc aggacgatgt ccgccagccg
     6421 gatcgtcgcg aggccgcgtt tggtctccac cgtgcattcg gtctcgtcac gggagcgcag
     6481 gtagccgagg gcgtcggtga acccgccttc gatccggtac cgcacgacga ccctcgtgcc
     6541 gaccgggacg tccgggaggg tcaccggttc aggtgcgcgg tgagctcgtc gtcgctcggc
     6601 tcgaccaggt gggtgccgtc cggccagacg atggtcggga tccgccgctc accgttctgc
     6661 agcgcgcgca ccgtctcctc cgcgccggag tccgcttcga cgtcgatgta ggcgtactcg
     6721 acgcccttcg agtccagcag ggcccggctg cgtttgacgt cggggcacca gccggcgccg
     6781 tacacgatca ggtcgctcat ggctcacagc atgccaggtc gcggtccggc ggcgtgttcg
     6841 gcgagggcgg cacggtcggc gagcccggtc ttggcgagca ggctcgcgac atgcttctcg
     6901 accgtccggg gcgagatgtg caggcgggcg ccgatgtcct tgttccccat ccgctcggcg
     6961 agcagcacga gcacctcgta ttcgcgcacg gtgaccccgg ccgcgcgcag gtcgccggga
     7021 acccggtcga ccccggagcg ccgctgccgc acgggcgctc cgagcttgcg gagcagggtt
     7081 cggcaggcgg ccgctaccgc ctggatgtcc ctcccgtgga agtactcttc agctgctttg
     7141 agccagccgg ccggatcgcc ccagccgtcg gcggcggccg gttcggcgat cagccggagc
     7201 ccgagatggc gggccagggg atagggcgcc gacgtctcca gcgcggacgc caccgcacgt
     7261 tcggcttcgg ccgcgtcgcc gcgtctgccg tgctcgacgg cctgcgcgaa ttcgacgaac
     7321 tgccggttcc agcgcatccc gctcaccgcc gatccgccgt ccgggcaagg cgctccgccg
     7381 agggtgtcga cgagcgtcct gagcccgtgc tggccggcga ggtggaaccg gctcggccgc
     7441 cggtcctcca gctcgatgac ctggccgagt tcgcggcggg cccggtcgaa gtcctcttcg
     7501 agcagcgaac agaagacccg tgccagcccg atgctgagca ccatctcctg cgcgttctcg
     7561 ccgccgcttt cgcggaagtc gtcgagggcc tgctccatcg cgggacggtc cgcccggtgc
     7621 ccggccgaca tcgccctggt catatgcgcg tactgcagca acgcggtcaa ccggagcctg
     7681 ccgagcacgg cgaggttctc cgcgagcagc gtgtgcgcgg tgccgaagtc gcagcgcagg
     7741 atcgcgtgca tggtgcgcac ggaatcgacc gcgcaatgca gcgtgatcga cccggtccgc
     7801 tgggcgtccg cgcgggcgag cagcagagtc tgctcgtcgc cgttcatgag cacgcggtgt
     7861 ccgccgagcc ggaccagcgc ctgggtgcgg aggtgatgca gatggttgtc ctcggcggtc
     7921 cgccgcgcga gttgcatgta gtgctcggat tcactgaggt cccgggacag cgcgagcatc
     7981 ccgagcacct gcaacgcctg gcagacgacg aacggctgct cggtcgcctc ggccaccttc
     8041 catgcctgac gcgcgagccg ctcggccgtc ccggtccggc cggggacgtc gagccagagg
     8101 ttcgcctcga cggcatcgag cgcggcctgc tgagcgggtg agatcgccga ccccagggga
     8161 gcgcgggcgc gttcgatctg gccgaggcat tcatcgtgcc gtcccgcgat gtaggccgcc
     8221 caggccagct gggtgcgcag tttcgcggcc cgttcgagcg tgccgatctc gccgaacgcg
     8281 gcggaaagtt cgacggcgcg gtcgaactgg ccggtctgcc cgagcgcgtg gaccagcgtc
     8341 tccagcacct cggcccgatc acccgcgtcg gcaccggcga gcaggtcgag ggccttcgtg
     8401 agcatcgtga ccgcggagtc cgcggcgccg gcgtcgagcg cgcgacggcc ggtctccgcg
     8461 aacaaccggc ccgcagcccg ctcgtccagg gcggtcagcc ggagcgacgc gacgagcgcg
     8521 cacaggtcgc ccggcaggcc tgggtacagt tcctcgaccg cgtcggcggt ttgacgggcg
     8581 agttccgcct ttcgcgccgg tgactggcgg gccagcaacg cttccgcggt cagcggatga
     8641 cggaaggcgt accagccggg tgtcatctcg tcggtggtca ccaggttggc ggagaccgcg
     8701 gcgccaaggt gattgtgcag cgtccggtcg ttggtcccgg tgaccttctg caccaccgtc
     8761 agcgggaagc gacggccgat gatcgccgcg accgaaagca gttcacccgc ctgctcgccg
     8821 agttgctcca tccggacgcc gatactggtg accagcgcgg cggggacgcg ggcgcggagt
     8881 tcaccgatga cgcgccagcc gtcgcggccc tcgaccagca ggccgtcgtt caccatgccg
     8941 tgaagcagtt cctcgacgat gaacggaagg ccggcgctgt tgcgccacaa cagttccgtc
     9001 gcggccgacg gcagccgctc cggctcggtc tcgaggcagg cggcggcgag cgcgtgggtg
     9061 tcggcgaggc cgagcctgcc gagttcgacg acggcgcagc tcatccgttg tgctccggag
     9121 gtcgccaggc gcagcgcgtc ggagggttcg ctgcggagcg tgccgacgaa caaggtgtgc
     9181 gccgcgggca ggttgtcgac gaggtattcg aggatgaaca gcgtctcggc gtcggcgtcc
     9241 tggagatcgt cgagcaccag cagcgcaccg cggtcgcggc tggtgacggc cagcagccgg
     9301 aacaccgctt cggcgagcac catcagggag ccggactcgc gaggccggtc tcctcggctc
     9361 caatcgggga tgagctgggc gagcacgggg acgaacgggt cgagttcggt cgcctccggc
     9421 gggcctccgc cgcgaaaatg cgacagcagt gcctgggtga gcggccggaa cgggacgagc
     9481 gggccgatcg aactggccct gccctgcaac accgggacgt cggcggcgac cgctcgcgat
     9541 gcggcttcga tggcgagccg cgatttgccg acgccaccct cgcccacgag aaagatcgcg
     9601 ccgccgcgac ccgcgatggc gcgatcgaga gctccggaga gctcggccag ttcggcgtcg
     9661 cggccgatca tccgcgacga acggataccc accgccgtga ctatagcgag cggattccgc
     9721 tgtcacggcc aaaagtcgat cacgaaggcg ggcggcgcga acccgccttc gtgagcgtta
     9781 ctcagatcca gccgccggtg aagacgctga cgacggacgg agaaccggtg tccgtggaca
     9841 gggtggcgag cgggttggca ctcagccgcg gcttgctgcc cgccagcgcg tggttgcgcg
     9901 agccgacctc gagggcacgc ggcaggttca cggcgccgag gacgtcttcg gtggcgggca
     9961 gatctctttc gtacatgtgg ttcttctcct catactcggt ttaccggcgg aaaacggtgg
    10021 ccgcgggatg cggccggtcg gggcgtagca ggagcgcgga ggggacccgg tcgccgaatc
    10081 ccagccgcaa caggccgtag ccgatccccg ccaggccgct cagcagccct ggcgagggaa
    10141 ccgcgccggg tgtgccgcag cgggcaccgc gctggtcgat ggcggcgagc agatgaccgg
    10201 tccggcggcg taccgcggcc gcggcgccag tgtgcccgtt ctccgccagc acgcacaaca
    10261 cgtccagcac tccggactcg ccgtggcaga ggctgagatc cttcagcggt gccctgtcgg
    10321 tcagccgtcc gatcgtccgg tccagatccc tggcgtactc gggatccggc aggtgcgcgg
    10381 ccgttccgag ggcgtcgccc gtgaggccgt cacaccaccc gccggtgctt tccgtccgat
    10441 cgtccgcctt tccgggcggt tcttcgccgg gacgttcgtg tgcccgcagg acccagtcga
    10501 tcccggccga accgcgggcg aaggacttct ccacgggacg ttcgcgttcg agcagctgtg
    10561 tcgcgtagcg gtccgcccgt gccagcgccg tctccagtcc tgtttggaca tacaccgaac
    10621 gcatcgaggc gacgccaccc gcgagtccgg tcgtgaaacc ggagggtgtt tcggcggtgg
    10681 cctcgggcat caggtcgacg gcctgctcga tgagatcgcc cgcgggaagc ccgaccagcg
    10741 tgctgagccg ggcgatcgtg tacgcgacgc cgccgagccc gagcagcccg ccgcagccgg
    10801 cggtggcggc caattcgcgg tcggcgcgga gggtggcgaa aaggccgggg agcgggctga
    10861 tcgcgtacgc ggccagatcg cggtagcgcg cgatcccggt cagctcggcg agctgggcga
    10921 ggaacaacgc cacaccgcag tagccctcgc cgagcccggc gcccatcggg agaacggtcc
    10981 agtagcggtc gtcgacgagc tcgatgccga gccagttgga gcggtgctcg tcggagaagg
    11041 cgctggcgac gatctggtcg gcgatcccgc acgcggtgac cagtagccgc tccgcgtcgg
    11101 gcgcctgatt cggcaccgcc gtctccgcgg tctcgccgtc gccgtggtgg ccgtcggccg
    11161 ccgtgctgat ggcgagggtg gcggtgatca gccactcctg atcccgctga tcgagcggat
    11221 ccatgtcggc gaccttcgcc agcacggtgt ccagcgacgg ccgctcgacg accccttcga
    11281 cgctgtcgcc acgcgagtcc agcagcgacg tcgagccggg gttcgaggtg aacatcggca
    11341 cgtcgcccgc ccacaggtcg tcccgctcgt gcggcaccag ccggagcagc ttctcctccc
    11401 gcaccgagtc gtcttcgagc aggtcgaacg cgtggtcgcg gtcggcggcg tcgcgaagca
    11461 ggtcggggtg ggtggtctcg tccaggaggc gggagtagaa gttcgtcggc cggatgagca
    11521 cccggatggg atcctcggcg cagcgccgga ggagctcggc gagctcgtcc cgtccggagg
    11581 agatcgcgtc gtagccgagc cggaacccgg ccagcagcgc cgcgctgtgt tcggcgggag
    11641 cgacgtcgcg gccgtcgagg cgcggcaggt tgtggcttcc ggcgagttct ccgggcactc
    11701 ggaccaggcg catgcggtcg gtccccgcgt cggcccaatc gacccggtcg gtgggcagct
    11761 tgccgccgcg gccggcgaga ccggagatgt cgacggcacc gtgctcgccg gcgaagagct
    11821 gggggagcag cagcgtgcgc tgtaccgaac gcgccagcat cgccgccgcg gggtcgccct
    11881 ccggcggaac gggtggggac ggctggaaca gggtctcgat gtcgatcagc accggctggt
    11941 cgccgcaggc gatgatgttt tcgtagtgga cgtcggtggc gtcgagcgcg tggaggagcg
    12001 ccaggaggat gccctgcctg cggtagaagc ggtcgacgtc gccgaggtcg gcgcacggcc
    12061 ggtgctcgac gaaccggagc cagccgtagc cgtcacgcgg cagcgcgtcg gcggtccgca
    12121 gttcaaggcc cggcagccgc ttgttgagct gttcgacgac gtcggtgaaa cgctcgtgca
    12181 ggatcagcgg gcggggtttg tagatcacct tggcgccgct ggaaaagcgg agcagtttga
    12241 ccgaacgtcc acctgcgtgc gagtcaccga atccgcccgc gacctcgacg agcgtgccga
    12301 gttcgccgtc gacgaccgtg cagggcagca aggccgcgtc ggccgagaac cgggcgagcg
    12361 tttcggcgtg ggcttcggcg gcgtacaggc aggcctgggc gaggagcctg gccagcaccg
    12421 ggtattcgcc gaacaaccgg gtgagcccgg ccggcgtcga ttgacgccgc acgaaatccg
    12481 agaagcgttc ttcgggtgtc gcgccctcga gggttccggc cttgcgggca cggtggagtt
    12541 cgaggaccag cgtgcggacc gaaaggttga gcaggtgctg gtcgagattg gccgcgaaac
    12601 cctgacgaag cgcatcgacg tcggcgccgg ggagatcgtc cgggaccgcg tcgcgcgagg
    12661 cggcgtcgac gagagacctg aagaccccgg cgaacgccgc acgccagtca ccgactgggg
    12721 ggcgctccgg cagaagcgtg gtgatggcgt gttcggcgaa gtcggcccag agaggcttgt
    12781 ccgctgaccg ttcgcgcggg gtccggccgt gctcccacca cctcggcggc agggacgtcg
    12841 ccgatggttg gggcgtcacg gcggtaatgc tttcagctcg gcgcggtacg cacatggggg
    12901 cggcaccccc acattcagcg cacgcacgaa gatgtccgga gagtgaccac cgggcacgga
    12961 cggtggccgt ccgatgccgc accggaatat ggggtcccgg tacccatgtg cgggcaccgg
    13021 ccccgtcgca ccatggtgag gaggtgccgg gcgcgggccg gtttccctgg gggtccggcc
    13081 cgcgccggca aggggctcct cgggcatgat cggatcatgc gcgtcttgtc ggaaagccag
    13141 ctcggttccg ttctcgcggg cgtgcccgct acgtgcccgc gagtggtggt gagcggcaat
    13201 ttcgccacgc cgatgcgggc gctgaaggtg ctggacgcgg cgctggcgga gtaccgcttg
    13261 ttcgcgttga acgcccaggc gggcatgccg gaccgcgagg gtgttctgct ggagacgccg
    13321 ttcgtgggcg cggggatgcg cggccgtccc gggctgcggt acttcccgtc ccggctgtcg
    13381 ctggtgccgc agctgctcaa acactcgctg ccgccggacg tcgtcctgct gcacacctcg
    13441 gccccggtgg acggcgtggt gtcgctgggt acggaggtga acatcctgcc cgcggccatc
    13501 gaggcggtgc gggcccgcgg cggcctggtc atcgcgcagc tcaatcccga gatgccgttc
    13561 acctacggcg acggtctcgt gccggtcgac gagatcgact acggcatcga ggtcgtggaa
    13621 gcgctgctgt cgccggtccc gcggccggtg ggggagacgg cgcggaccat cggtgagcgg
    13681 gtggccgggc tggtcgagga cggcgcgacc ctgcagctgg gcatcggcgg gatccccgac
    13741 gcgaccctgg cagcggtgac cggacggcgt gggctcgcga tctggtcgga gatgttcagc
    13801 gacggtgtgc tcgcgctcga ccgcgcaggg gcactcgatc cggcggaacc ggtgacggcg
    13861 tcgttcgtgt tcggcagtgc ggacctgtac cgctggctcg accgcaatcc gcggattcgc
    13921 ttgctccgca cggaaaagac gaacgatccc gcggtgatcg cccgccagcg cggtctggtg
    13981 tcggtcaaca gcgccctcga ggtcgacctg tacgcccagg ccaacgcgag ccgggtgaga
    14041 ggggcgatct attccggatt cggcgggcag accgacttcg tggtcggggc gttgcattca
    14101 cccgggggcc gggcgatcat cgcgctgccg tcgtggcatc cgaaggccga cgtttcgacg
    14161 gtcgtgcccc ggctgaccgg tccggtgacc tcgttccagc acagtttcgt ggtcagcgag
    14221 cacggtgtcg cgacgatctg gggcaacgac gcgagcgagc aggcgcggca gatcgtcggc
    14281 caggtcgcgc atccgtcggc cagggaagaa ctcgtggcgc ggggccggga actggggttc
    14341 gcgctttagc ggtattccat tccggcgtga aaaccggaac ccggtaaagg gacacgaacg
    14401 tgccccttta ccgggtcgca aacacgaggg gccgacccgc gccaacagat tggcccccgt
    14461 caatccctgt gcttagagcg tcagaccagc catccgagca cgtgggccag gtgcgcgagc
    14521 agacccgaaa tgaggtcgtg accgtggtgc acgtgctggg tgaacatctg cattgagggg
    14581 ctccttgttc ggatttcgtg ttcggttgtg ctctcgcgag gagcgatcga agattttcac
    14641 cacattggca ccctgtcaaa aaacgatttc ccgggctttc gtcgggtcgt gaatcttcct
    14701 acgataaaca cgtaagtctt tcgtgttttg cgccaggggt gggtttcggg agcgatgaca
    14761 ccgtgcgtag cggggttgcg gcgggtcgat gtggacgctg agcctccgct acggcaagtg
    14821 ggcggcgggg tgacacgaac cggtgatcca cttgccacga atggtgaatc ggcgagtatc
    14881 accgatacgg gtgacgtgac gaggtcgtcc accacccatt cggccagaag acggacacct
    14941 ttgccgggcc cgcggacgtg cgcgaccggg gcacgacccg cggtggtcag gccgaggccg
    15001 cggtcagggc ctgaagttcg gcgtcggaca gtcgcagctc ctcgaaggcc agcagtgacg
    15061 gcaactgctc aagggtgcgc gcggaggcga tcggcgcgag caccgtcggc tgccgcgcga
    15121 cccaagccag agcgacggtc gccatctcga cgcccttggc cgacgcgatc ttctccaggg
    15181 cggcgagtac tttcgtgccg cgctcggtgt ctgcgtaacc accggcgagg ccaggcaggt
    15241 cgcgcacgct gtcgacgggc tttccggggc ggtacttacc ggtcaggaag ccggaagcaa
    15301 gagcgaagta ggggatgcag gccagccctt cgctgcgcgc gacgttccgc aggtcgccct
    15361 cgtaagtgtc gcgcgacacg aggttgtacg gcggctggag cgcgacgtag cgtgccaggc
    15421 cttcccggtc ggagaaggcc agcgaagccg acagtcgctc ggggccgatg ttggaggccg
    15481 cgatcgcgcg caccttgccc gccttcacga ggtcgtcgag cgcggtgatg atgtcttcga
    15541 ccgggacgga ttcgtcgtcg aaatgggtgt agtagagatc gatacggtcg gttcccagcc
    15601 gtcgcaggga ttcctcggcg gcggccttga tgttcgacgg tgcgaggccc ttgtaccggg
    15661 ggtggtcacc gaccttggtc gcgacgacca cgtcgtcccg gccgcggcgg gaggcgagcc
    15721 attcgccgat gatggtttcg gactggcctg cttcgttgcc gggaaagtga aacatgtacg
    15781 agtcggcggt gtcgacgaag ttgccgccgc cggcgacgta ggcgtcgagt acctcgaacg
    15841 attctcgtcc gtccgctgtc cagccgaaga cgttcccgcc caagcacagc gaggacacgg
    15901 tgagaccgga gttgccgagt gggtgacgtg caagcatgat cgattggacc acgatccgat
    15961 cgcgtgagtc cgtcggacgg gaaggtttgc acgttcgtac ggtacggagt gcacttccgt
    16021 cggcgaagca tcagcagaag acctctgtga ggagcttgac gaacgccggg ttcgagtcgc
    16081 ccccggtcgg cgcgctcgtg gccgaaagct ccagccgctt atgggtgtcc ggcgtggtca
    16141 gcagttgcga ggaatagccg gggataccgc cgccgtggcc ccacacccgg gtgccgcacg
    16201 gcagggtctg cacctgcagg ccgaggccgt actcggggct gaccgcggtg gtcttggaga
    16261 tttccttctg ctgcgcgggt tcgagcagcc ggccgcccgc cagcgccacg ccgaaggtgt
    16321 ccagatcgcg ggtcgtcgag atgatctcgc ccgccgccca cgcgaccgac gggttgaggc
    16381 gcgtgatgtc gaccggcttg cccgccacgg acacgtagcc gtgcgcgtgc gggccgctga
    16441 tgccgacgtc gtcgccgggg acctccgtgt cgtggaggcg caacggcttc agaatccgtt
    16501 gctcgaccgc cttctcgtac ggcttgccgg tcaatcgttc caccagcaga ccggcgacca
    16561 cgtagttggt gttcgagtaa ctccaccggg tgccgggatc gaagtcgagc ggcctgccgg
    16621 tcgagatctt gagcagttcc cgcggtgtcc agtgcttgta gcggatcttc tcgaactcgg
    16681 cagggtcgag cggcaacgcg tcggtgtagt tgtagaggcc gctggtgtgc tgcaggacct
    16741 gacggaccgt gatgcggccg tcgatcaggc cgggcaggta acggacgacc ggcgcgtcca
    16801 gatcgagccg gccttcgcct tcgagttgca gcaacaccgt cgacacgaac gtcttggtga
    16861 tgctcccgac gcggaaccgg ccgttctccg ggaccggccg attcgacccc agttccgcct
    16921 tgccggagcg cgcggtgaag cgctggtggc cgtcggtcac cctggcttgc acgccgagcg
    16981 ctcctccgct tgtggtgagc tggtccagcg cctcctgcac gaccttgcgg tcggcgccgg
    17041 agtcggccag cgcggtgcct gtggtggcga tcagcccggc agtggtgagc gcggcgacaa
    17101 gccggatcct cagcgaaggc cgcgagagtt ttctttgcat gatgcggaaa tcccccttag
    17161 acgcccgaag gctctcccca aaagaccgtg agccgacgct agcgtccgac gttcaccgcc
    17221 cgcagtatcc gaaaatcaca accacccgaa cagagcagat cacgcgggag cggctgatcc
    17281 gttcgcccca cgtttcctca tatcgaaaac cgtggaacgc cccttgtcgc tgctggtttg
    17341 ctcgacgcga ccagtgcgaa ccaggggagg tttcatgaag cgatcattgg ccacgtcact
    17401 ggcggtcgtg ggggtcttga cgacatcact gatcccggtg accgcgtccg atgccgcgct
    17461 gctcgccaga ccggactatc ccgccgcacg gtgggtagcg gccgatccgg gcaactgggg
    17521 cagccgaaac ggcgacacca tcacgggtat cgcactgcac accttcgatc ccgtaccgcc
    17581 ggcggtaccg gactacgaca gcacgatccg gttcttcgcc aacccgaacg cggcccagac
    17641 gagcgcgcac tacgtgatcc gctccagaga cggtgacatc acgcagatgg tgcagaatca
    17701 ggatcgggcc aatcatttgc gcggtcacaa cggcaatacg atcggcatcg agcacgaggc
    17761 gaccagccgc gaagagaagt ggtacaccga catcatgatg cgttcgtcgg ctgctttggt
    17821 gcgcgatctt tgcgaacggt atctgattcc gaggacaggc agttccgacc cggacgggca
    17881 gagcggcggg atcagagggc acaaccagtt ctccggccac gagggcaatt ccgaccccgg
    17941 caggttctgg tacgaacggc acgacgcgta tctgcagaag gtccgcgggg gcaagcggga
    18001 cgcggccgtg ccgttcggcg ggcagtatca gatcttccag cgtcagcggg accacagcgt
    18061 ccaccagcgg gtatgggacg gttcggcttg gcgtggctgg gccgacctcg gtggatcgtt
    18121 cgcgggcgag cccgccgccg tcgcgttcgg gcggcagatg cacgtgttcg ggatcgacag
    18181 ggccacccgt cagctgcgca cccggtattg ggatccgtcc ggcggttggt cgaactgggc
    18241 cgagcctggc ggaacaccgg cccggctgcg gggcaacccg tccgcggtcg tgatcggcca
    18301 gaacctccac gtcttcgccc gcggtgagaa caaccaggtc tacgaggcac gctggtccga
    18361 tggcgcgtgg cggtggacga acctcggggg tacggtcgtc ggcgacccgg ccgcactcga
    18421 tttcggcggc caggcccagg tgtacgcgct cggctccgac cagaggctgt acagcaacgt
    18481 cctcggtggc tcgggctggg gcggctgggc gaagagcgga gagcccggtg cgcggttgaa
    18541 cgggacgccc tcggtgatcc gtttcggcgg tcaggcgcag gcgttcgtgc aggggctcaa
    18601 cggcaacgtg tatcaggccg tgtggaaccg ggaaggtgga tggacgtggc acaacctcgg
    18661 cggtgcgatc ttcggtgacc cgtccgccac ggtcgtcgga tccacggtcc gggtgacggc
    18721 cctgggaacc gacaatcagc tctggaccga ctcctggtcg gcgaacggct ggaccggctg
    18781 gcaaaaggcg gcaggcgggc cggcgggcgg gctcaccggg acgccgaccg cgatggcctt
    18841 cgggaaccag ctccaggtca ccgtgcaggg gctgaacgga cgcgctcacc aagccgcgtg
    18901 gcagcccggc agcaactggt ggtgggccga cctgggtggc acggcggcga actagcggtg
    18961 agcgtgccct tgctacgcga ccgcttcggc caagcgggcg aagaacaccg gcctgcttga
    19021 tccgattggc gggtattccg tcccgcatat cggcaacatc atggaaagca acctcggggg
    19081 gccagggtgc tgcgaattca cttcaccgac gcggatattt ctcggatcac catcgcggag
    19141 gacgtcgatg cctcttggga gacgctgttc agtctccacc ttttacaaga acccgacgaa
    19201 atcctctcct tcgaccattg gcggcgccgg ataagagcgg aactgcccgc ctggattccg
    19261 ctcctgctgg agttggcgcc gcctcgcggc tattccgcgg actttctcac tccgggacgt
    19321 ggagatgccg actcggatac ggtgatcgat cggatcatgt ccactccacg ccgtcggttg
    19381 cgggacgacg tggcctgtct cgtggatcgc cggccgccga cgccgtggac acgcaagctg
    19441 gcgaacggcg acgtcaccgc cctgcggcaa ctcggtaccg ctctcgatcg gtactaccag
    19501 cgggcggtcg cgccgtatcg ggggcggctg cgcgcgcacg tcgaggcgga ccgatcgcgg
    19561 cgcggcaagg cgttgctgac cggtggggtc gaccggctcc tcgccaccct tcatccgcgg
    19621 gtcgagtggc ggccaccggt gttgcgggtg ctcgactacg tcgaccagga cctccatctg
    19681 gacggcagag gcctggtgct gcttccgtcg catttctgcc gccaccatcc ggtcaccctg
    19741 aaagacgccg atctgccccc ggtgctcgcc tatccggtga gctccagttt cgcctggctc
    19801 acgccggaca ggccggccac gcaggatccg gtcaccagcc tgctgggccg cacccgggcc
    19861 gccaccctcc gcgccagcac caccgcggtc accacgacgg acctggcccg ccggatcggg
    19921 ttgtcgccgc ccagcgcgag caaacacgca agggtgctcc gggaggccgg tctgatcacc
    19981 acccggcgcg atggcggcgc cgtcgtccat caggtgtccg gcctcggcgt ggcggttctc
    20041 aacggtgagt tgcccgcctg aatccccacc cgccgtccac gacctggtgg caacgggtcg
    20101 gcggactccg ccaatggtag gaatgcctgg tgaccgaacc gaatctgatc gaagcagccg
    20161 ccgaagaggc agtcaccctc accagtgaac tgatccgcat cgacaccacc aacaccggtg
    20221 accccgacac gctcgtcggt gaacgcgccg cggccgagta cgtcgccgag aagctcaccg
    20281 acgctggcta cgagatcacc tatgtcgagt ccggcggcaa gaaccgccac aacgtgatcg
    20341 tccggctgcc gggcgcggac ccctcgcgcg gcgcgctcct gatccacggt cacctcgacg
    20401 cggtccccgc cgacgcctcg gagtggtcgg tgcacccgtt ctccggcgcg atccaggacg
    20461 actacgtctg gggacgtggc gccgtggaca tgaaggacat gtgcgcgatg acgctcgcgc
    20521 tggcccgtca ctacaagatc aacggcatcg tcccgccgcg tgacctcgtc ttcgcgttcc
    20581 tggccgacga agaggccggc ggcaagtacg gcgcgcagtg gctggtcgag aaccggccgg
    20641 agctgttcga gggtgtcacc gaggcgatca gcgaggtcgg cggcttctcg atcacgctga
    20701 aggacaatgt ccgcgcgtac ctcatcgaga cggccgaaaa aggcatccgc tggatgaagc
    20761 tgcgggtgcg cggcacggca ggccacggct cgatgatcca ccgcgacaac gccgtcacca
    20821 agctgtccga ggccgtcgcc cggctcggca accaccgctt cccgctggtc atgaccgact
    20881 ccgtccgcga gttcctggac ggtgtcaccg agatcaccgg ctgggacttc cccgaggacg
    20941 acatcgaggg ctccgtcgcg aaactcggca acatctcccg gatgatcggc gcgaccctgc
    21001 gcgacacggc gaacccgacg atgctcaccg cgggctacaa gtcgaacgtc atcccgtcgg
    21061 tcgcggaggc ttcggtcgac tgccggatcc tgcccggccg tctggaggcg ttcaacgccg
    21121 agctggacga gatcctcggc ccggacatcg agaaggagtg gatggagctg ccgccggtcg
    21181 agacgacctt cgacggtgcc ctggtcgacg ccatgaccaa cgcggtcctc gccgaagacc
    21241 cgggcgcccg cacgctcccg tacatgctct ccggcggcac cgacgcgaag tccttccagt
    21301 cgctcggaat ccgcaacttc gggttcgccc cgctgcagct gcccgcggac ctcgacttct
    21361 cggccctgtt ccacggagtc gacgagcgcg tcccggtcga cgccctgaag ttcggtgtgc
    21421 gcgtgctcga ccgcttcctg cgctcggcct gatgcccggt ctgctggccg ccgacgggac
    21481 acccctgcac ttcgagcgct ggggtgatcc gtcggcgccg gtgaccgtgg tcctgctcca
    21541 cgggtacgcc ctcgacaggc ggagctggcg tgccatcgcg ccggtgctgg cggaagccgc
    21601 ggagaagccg gtcgcggtgc tcgcctacga ccagcgcggg cacggcgaat ccggtgaggt
    21661 ccgggcggcg tcggcgacca tgggacacct cgccgacgat ctggccgagg tgctggagaa
    21721 ggtgattccc gacggcaagg tcgtcctggt cggccacgac atgggcgggc tcgcgatcct
    21781 gtcgctcgcc cagcggcacc cggaggtctt cgcggcgaga gtggcgggaa tcggattgct
    21841 cgcgatgtcg gcgggaggtg tcaccccgga cgcgatctgg ccgaacgcgc tcgggaagct
    21901 cggtcgcgac ctggagatgg tcttcgggac gaaactcatc ggtctggtcc gggagcacac
    21961 gagcaaggcg gtgaccgccg ggctgcggtg gtggctcttc ggggacgacc cggtgcccgc
    22021 cgacgtcgaa ctgacggtgc ggatgatccg cggcaactgg ccgcagacgg tgtcggcgtt
    22081 ccgtccggca ttggacgcct acacacggga atccgcgttg tcgcaggtcg gcgcggtgcg
    22141 gaacgggacc tcggtggtgt tgcccggggt cgggcatgtc gtcccgctcg aagcggctcc
    22201 gcaggtggtg ccccgcctgc tggccctggc gaaccgggct caccgacaag actgaccttc
    22261 ttgacaaaaa ctcttttcgg tgacaccttc ttggcatgtt ctccgttgcg gtgatcgagg
    22321 acgcggaagc ggccgaagtg tcgctggatc cggtccgggc aaggttgctc gccgaactcg
    22381 ccgagccggc gtcggccacg atgctggccg cgcgggtgga cctgccgaga cagaaggtga
    22441 actaccacct tcgcgcgctg gagaagcacg ggctggtcga gctcgtcgag gagcggcgga
    22501 agggcaacgt caccgagcgc atgatgcgcg cgacggcgtc ctcgtacgtc atctcgccga
    22561 cggcgctctc ggccgtgcaa cccgatccgg cgcagtcacc ggaccgcctg tccgcgcgct
    22621 ggctgctcgc ggtggccggc aggctggtgc gcgacgtcgg cctgctgatc accggagcga
    22681 ccaaggcgcg caagcgggtc gcgaccttcg cgatcgacgg cgaggtgcga ttctcctccg
    22741 ccgcggaccg ggccgcgttc gccgaagagc tcaccgtggc gatcacgaat ctggtgagca
    22801 agtaccacga cgaaggcgcc gaacagggcc gcgatcaccg gatcgtcgtc gccgtccac
//
