LOCUS       NZ_FNHE01000003        11002 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Geodermatophilus siccatus strain DSM 45419, whole genome shotgun
            sequence.
ACCESSION   NZ_FNHE01000003
VERSION     NZ_FNHE01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Geodermatophilus siccatus
  ORGANISM  Geodermatophilus siccatus
            Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
            Geodermatophilaceae; Geodermatophilus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900103785.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:00:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,951
            CDSs (total)                      :: 4,891
            Genes (coding)                    :: 4,846
            CDSs (with protein)               :: 4,846
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 11 of 45
            Pseudo Genes (incomplete)         :: 37 of 45
            Pseudo Genes (internal stop)      :: 5 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:54:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 11002
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNHE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11002
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     gene            <1..695
                     /locus_tag="BLS21_RS05880"
                     /old_locus_tag="SAMN05660642_01190"
     cand_cluster    1..11002
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11002
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4541:6002](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4542..6002)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     CDS             <5..695
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003878491.1"
                     /locus_tag="BLS21_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01190"
                     /product="IS481 family transposase"
                     /protein_id="WP_139177030.1"
                     /transl_table=11
                     /translation="VHRVLVRCRINRLWHVDRVTGEPIRRYEMTRPGELVHVDVKKLGN
                     IPDGGGWRIHGRALGSRNSQAHRNPARPRKVHGRANLGYCYVHSAIDGYSRLAYSEALD
                     DESAATALAFWARARSFFAGHGITVERVLTDNGSAYCSHAWREEHRRLGIRHSRTRVRR
                     PQTNGKVERLNRTLLEEWAYRRLYTSETARRAALSAWLHHYNHHRPHTALGNLPPITHC
                     TNVSGQYS"
     gene            complement(692..994)
                     /locus_tag="BLS21_RS05885"
                     /old_locus_tag="SAMN05660642_01191"
     CDS             complement(692..994)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS21_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05660642_01191"
                     /product="hypothetical protein"
                     /protein_id="WP_091215155.1"
                     /transl_table=11
                     /translation="MADDDLQRLVQRRLMELSSSAQAASRRAQWAIAPETIARIAAGRH
                     SGMVSERLAAALARALDVPENRVRRVVGLPLVEDSRADVCTGPHLRVVRDDGRLA"
     gene            complement(1005..1673)
                     /locus_tag="BLS21_RS05890"
                     /old_locus_tag="SAMN05660642_01192"
     CDS             complement(1005..1673)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013053.4"
                     /locus_tag="BLS21_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01192"
                     /product="cysteine hydrolase"
                     /protein_id="WP_091215157.1"
                     /transl_table=11
                     /translation="MQQAFGMAVPETVGEMCRPTTSAVLVYDAQVGILAHVQDRDRLVE
                     RIGAVLRAARASGVPVLYVRHVSLPPTHMGVAALRTAMAWQRLGDAAAVTAAFPPDAPH
                     TQLAGELAPVDGEPVLDKLGMSAFVGTPVEQVLRDRGVTTLVLVGAVLEIGIEPTARHA
                     ADLGLLPVVVQDACGVVDPEAAQRSLASLDYSLLTYRCSSRDVVDAFGAVGVPRGAPSA
                     "
     gene            complement(1764..2486)
                     /locus_tag="BLS21_RS05895"
                     /old_locus_tag="SAMN05660642_01193"
     CDS             complement(1764..2486)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012947220.1"
                     /locus_tag="BLS21_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01193"
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_091215159.1"
                     /sec_met_domain="PIG-L (E-value: 2.1e-18, bitscore: 62.3,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLAVSPHLDDAAFSAGGTLAALAATGHEVTVVTCFTASVPDPA
                     GFALACQLDKGLPADVDYLALRRDEDAAAMAVLGASPVYLGLPEAPHRGYTSAADLFAG
                     AHEDDQVWRSLGAALEGHDADLWLAPQALGGHVDHLQVLRAVAGLDRPVLWWRDSPYVL
                     RDPAAVPGPALPGGLAEVHLPQDLDRRADACACYPTQLGFQFGGVEQMRTALAGLPEVL
                     LAGDRAREVLATAAVPAG"
     gene            complement(2483..3691)
                     /locus_tag="BLS21_RS05900"
                     /old_locus_tag="SAMN05660642_01194"
     CDS             complement(2483..3691)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012947221.1"
                     /locus_tag="BLS21_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01194"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_091215160.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.6e-31,
                     bitscore: 104.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTCFVSRRYWPAVSGMSVYAENLLRELVALGSEVTLVSQYRDDE
                     AGTRVYGGGPPPPDRVPAGVEVVALPSRGETVVPADWEGDIDEIVRTVVGLHAERPFDV
                     LHAQYGYPPGLAVLAAARETGLPAVVSIQGGDGHWLGTCCTTHAEAMRTVVDSSSAVLI
                     GSASFRDEVVGNLGSDPARFTIVPGATDTRRFTPAERPLGALREPPVLLFHGRVDRRKG
                     VLDLLEALPDGVRLVVSGIGPDLDEARARADERTTFLGYVPPDRAPEVYRSADVFVSPT
                     YSEGFSNTLLEAMASGLPTVSTDSVGVVDCLRHEENGLLHAPGDVPGLRAALTRLLDDG
                     ALRTRLATTALEEVRRLYSWPVLAASIDAVHRSVVGTTPSAGWSMPSDVDLSCRFRSAA
                     HLL"
     gene            complement(3688..4545)
                     /locus_tag="BLS21_RS05905"
                     /old_locus_tag="SAMN05660642_01195"
     CDS             complement(3688..4545)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012947222.1"
                     /locus_tag="BLS21_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01195"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_245700094.1"
                     /transl_table=11
                     /translation="MTELARSPRELRYAYNTNGLTSHRLSDALSLLADTGYAGVALTLD
                     VVHLDPFAPDALAQAEKTRARCDELGLGVVVETGARYLLDPRGKHEPTLVTPDAAGRAR
                     RLAYLRLACDLAEVLGAEAVSFWAGVPRPGVDRDEAWGWVVDGVRALVDSHGGRSYALA
                     VEPEPGMLVEDCDGWARLAEEAPGITLALDTGHCVVAGAYEPQEAVAAFAAHLGTVAVE
                     GMRRGVHDHLPLDEGDVDLPAVLRALRDVGYERLVTLELSRDGHRAHEMVPRAIATLRE
                     AERA"
     gene            complement(4542..6002)
                     /locus_tag="BLS21_RS05910"
                     /old_locus_tag="SAMN05660642_01196"
     CDS             complement(4542..6002)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="BLS21_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01196"
                     /product="YcaO-like family protein"
                     /protein_id="WP_217636014.1"
                     /sec_met_domain="YcaO (E-value: 9.2e-55, bitscore: 181.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTLTAAQRYLDSFPGTVEEFAIEGLDVLDVPLHSAVLPPGPRH
                     PGGSGLGYGATREEARTGALGEMAEMALSLRAHRGVEREQGSYAEMTRRHGRDRVADPR
                     TLCLEAGSAYDDDRPLQWLPMTRQRDGETVLVPAELVASAPDDLPGAPPPGGWLTTVIT
                     NGQGAAFDADRAVAHALLEVLQRDGNATSFRAMDRGVVVDLAGLRDPDALALLDRLDAA
                     GIDVVVKLAATEFGVADVYAVGCSRDLSEPVPVMATACGEAAHPDRDTAVRKALHEFAS
                     ARSRKAFMHGPFDVVLPATPPGYLDSWRGGHPPERLVEEDRALEAMLAWTRMGTGALVG
                     LLQGSVLSRRGTVALTDLPTWSGDDLHGTVVDALHAAGHDVLVELQPSVGDAVAAKVLV
                     PGLEVETMSYGRIGERGVRRLLERGDPLVAVGADPGGWAGVHLAAEAEDRLGGPAWFDR
                     AGADRRVGGLYALYREPGRHTVAEVLAQ"
     gene            complement(5999..6871)
                     /locus_tag="BLS21_RS05915"
                     /old_locus_tag="SAMN05660642_01197"
     CDS             complement(5999..6871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012947224.1"
                     /locus_tag="BLS21_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01197"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_091215162.1"
                     /transl_table=11
                     /translation="MTNPYRGLLPDLPAYACTNCGHWQRWPEPGPLVCPVCADVRNALP
                     ENGFEFVTPAQVEELVQGFCRPTAVEGVTEFGTHPRFGLDSRGWVIESDAGLVGFECAP
                     WYTADVLAQLRRMAEAKGGFDVLASSHVHGYGALWQLQQELEPRVVCVGVRDLEWTKAF
                     RVTWPADDELELAPDLTLHRTGGHFPGHSVLHDRRRGVLFCGDSLKVDLDEAGAPVALS
                     AHKAFHAQIPLSHGELREYLTVVGALDFEAVATPFELVRGVTTDHVVHLVQRLLSGPPD
                     AAPVALEEL"
     gene            complement(6868..7851)
                     /locus_tag="BLS21_RS05920"
                     /old_locus_tag="SAMN05660642_01198"
     CDS             complement(6868..7851)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012947225.1"
                     /locus_tag="BLS21_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01198"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_091215165.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3.6e-25, bitscore:
                     84.1, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 5.3e-24,
                     bitscore: 79.7, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGVGWGVAGCGWVARDHALPALAATPGARIVALHDRDPGALARM
                     PVDAPAHADLGAFLATPGLDAVYVAVPNAAHREVVEAVAAAGKAVLCEKPLAADVADAR
                     AMVTAARDAGVLLGTAYDQRWHPAHVRLRELLPELGTVTAVRIVYCCWLPADWTPDGRP
                     HDNWRVDRARAGGGAAIDLAPHGLDLAGVLLGEDVVELRALLQRRVQDYPVDDGALLSG
                     RTATGVLVDLHVAFNTPDALPRRRLEVVGTRGMAVAVDTMGQTAGGSLRLHRPDPVDVP
                     FADDSPFAAQFAAFTAAVAGRVPWPYDAARDLALHRLLLTALGDAR"
     gene            complement(7932..8957)
                     /locus_tag="BLS21_RS05925"
                     /old_locus_tag="SAMN05660642_01199"
     CDS             complement(7932..8957)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012947226.1"
                     /locus_tag="BLS21_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01199"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_091215168.1"
                     /transl_table=11
                     /translation="MSTAAPAVPVVDGIPYARAGRDELRAEVAGLLARGEVDRARVALL
                     ADADDWWTEPAPPPEQLARVPAARTLREAMDLLGMGRVADYFAHRWSDPTHLAGLALLQ
                     QHWPGSRPVVDVACGTGTHLRELARRGCTDLLGVDVVWAKLWLARRFVCPSARYVCADV
                     TGVPDLGVPAPAYVLCHDAFYFLRDKPAAAAAMHELAGDGGTVVVGHAHVADPHGEPLT
                     PEGYAAVLGTDLLYDDADLTGALLEGRPPRPAPAAALHRSEAVALVAGDPLSPAPADLG
                     EPLPPLRPNPLYADGELRWPSERYAGEYGPRSAYLPARWPDPLPADAARRRLLVDLPEA
                     W"
     gene            complement(8954..9853)
                     /locus_tag="BLS21_RS05930"
                     /old_locus_tag="SAMN05660642_01200"
     CDS             complement(8954..9853)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012947227.1"
                     /locus_tag="BLS21_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01200"
                     /product="hypothetical protein"
                     /protein_id="WP_091215170.1"
                     /transl_table=11
                     /translation="MTGGSPALAELRPLLTEVGDAKRVRVADAPGSLAERAFARAWGRL
                     VAGEDAAAVALSETAAAVARARLAGIDGAVLRTAGLTGDDARDVLRRGFDEVAGPLDAG
                     LRARLREALPLAVPTPQPPPLAERLNRQPRAGATAPGRPRVVVEPPESHGDHCLTVAVY
                     GVLVAPVFGADPVAPFLVGLAHHLHNVVLPDAGFAGEVLLGSALDRVVTTLEERELAAL
                     PGPLAERLRTVLRLRADAGAPESQAFHAADVLDRVLQVHHHARAAAFTASQALDDLELV
                     HAGPVQAFHLDVLAAAGL"
ORIGIN
        1 ccgtgcaccg ggtgttggtg cgctgccgga tcaatcggct ctggcatgtc gaccgggtca
       61 ccggcgaacc gatccgccgc tatgagatga cccggcccgg cgagctggtg cacgtcgatg
      121 tcaagaagct gggcaacatc cccgacggcg gcggctggcg catccacggc cgggcgctgg
      181 gcagccgcaa cagccaggcc catcgcaatc ccgcccgacc gcgcaaggtg cacggccgcg
      241 ccaacctggg ctactgctac gtgcactcgg ccatcgacgg ctacagccgg ctggcctact
      301 ccgaagccct cgacgacgag tcagccgcca ccgcactggc cttctgggcc cgcgcccgca
      361 gcttcttcgc cggccacggc atcaccgtcg agcgggtgct caccgacaac ggcagtgcct
      421 attgcagcca cgcctggcgc gaggaacacc ggcggctggg catccggcac tcccgcaccc
      481 gggtgcgccg accgcagacc aacggcaagg tcgagcggct caaccgcacc ctgctggagg
      541 aatgggccta ccgacggctc tacacctcag agaccgcccg ccgggcggcc ctgtcagcct
      601 ggctgcacca ctacaaccac caccggccac acaccgccct gggcaacctc ccgccgatca
      661 cccactgcac caacgtctca ggtcagtaca gctaggcgag ccggccgtcg tcacggacga
      721 cgcgcaggtg cgggccggtg cagacgtcgg cgcgggagtc ctcgacgagc ggcaggccga
      781 ccacgcggcg gacccggttc tccgggacgt cgagggcgcg ggccagcgcc gcagccaggc
      841 gctcgctcac catccccgag tgccggccgg ccgcgatgcg cgcgatggtc tcgggcgcga
      901 tcgcccactg ggccctccgc gatgccgcct gggcgctcga ggacagctcc atcaggcgtc
      961 gctgcaccag ccgctgcagg tcgtcgtccg ccacccggaa caggctaggc cgacggtgcc
     1021 ccccggggca ctccgaccgc gccgaaggcg tccacgacgt cccggctgct gcagcggtag
     1081 gtgagcaggc tgtagtcgag gctcgccagc gagcgctgcg ccgcctccgg gtcgaccacc
     1141 ccgcaggcgt cctgcaccac caccggcagg aggccgaggt cggcggcgtg ccgggcggtc
     1201 ggctcgatcc cgatctcgag gacggcgccg accaggacca gcgtggtcac accccggtcg
     1261 cgcagcacct gctcgaccgg ggtgccgacg aacgccgaca tgccgagctt gtcgagcacc
     1321 ggttcgccgt ccaccggcgc cagctcgccg gcgagctggg tgtgcggcgc gtccggcggg
     1381 aaggcggcgg tcaccgcggc cgcatcgccc agccgctgcc acgccatggc ggtgcgcagc
     1441 gccgccacgc ccatgtgcgt cggcgggagc gacacgtgcc gcacgtacag caccgggaca
     1501 cccgatgccc gggccgcccg caggaccgcg ccgatccgct cgaccaaccg gtccctgtcc
     1561 tggacgtggg ccaggatgcc cacctgcgcg tcgtacacga gcaccgccga cgtcgtcgga
     1621 cggcacatct cgcccaccgt ctcagggacg gccatgccga aggcctgctg catgcgcggc
     1681 agcctggcag cccccggcag ctccgcgagc ggtcgagcac gcggcgggtg gggacggccc
     1741 cgggtcggca ggatgccggc ggctcagccg gccgggacgg cggcggtcgc gagcacctcc
     1801 cgcgcccggt cgccggccag cagcacctcg ggcaggccgg ccagcgcggt gcgcatctgc
     1861 tccacgccgc cgaactggaa gcccagctgg gtggggtagc aggcgcaggc gtcggcgcgc
     1921 cggtcgaggt cctgcggcag gtgcacctcg gccagcccgc cgggcagcgc cgggccgggg
     1981 acggcggccg ggtcgcgcag cacgtagggg ctgtcgcgcc accacagcac cggccggtcc
     2041 aggcccgcca cggcccgcag cacctgcagg tggtcgacgt gcccgccgag cgcctgcggg
     2101 gccagccaga ggtcggcgtc gtgtccctcc agcgccgcgc cgagcgaccg ccacacctgg
     2161 tcgtcctcgt gcgcgccggc gaagaggtcg gcggcgctgg tgtagccgcg gtgcggcgcc
     2221 tcgggcaggc ccaggtagac cgggctggcg cccagcacgg ccatcgccgc ggcgtcctcg
     2281 tcgcggcgca gggccaggta gtcgacgtcg gccggcagcc ccttgtccag ctggcaggcc
     2341 agcgcgaagc cggccgggtc gggcacgctc gcggtgaagc aggtgaccac ggtgacctcg
     2401 tggccggtcg cggccagcgc cgcgagcgtg ccgccggcgg agaaggcggc gtcgtcgagg
     2461 tgcgggctga ccgcgagcac cctcacagca ggtgcgccgc ggagcggaac cggcaggaca
     2521 ggtcgacgtc cgagggcatc gaccagccgg cggacggcgt cgtccccacc accgagcggt
     2581 ggacggcgtc gatcgaggcc gccagcaccg gccaggagta gagccgccgc acctcctcga
     2641 gcgccgtcgt cgccagccgg gtgcgcagcg cgccgtcgtc cagcaggcgg gtcagcgcgg
     2701 cccgcagccc cgggacgtcc ccgggcgcgt gcagcagccc gttctcctcg tgccgcaggc
     2761 agtcgacgac gccgacgctg tcggtgctca ccgtcggcag cccgctggcc atcgcctcga
     2821 gcagcgtgtt gctgaacccc tcgctgtagg tggggctgac gaagacgtcg gccgagcggt
     2881 agacctccgg tgcccggtcg ggcgggacgt agccgaggaa cgtcgtccgc tcgtcggcgc
     2941 gggccctggc ctcgtcgagg tccgggccga tgcccgagac gaccaggcgg acgccgtcgg
     3001 gcagcgcctc gagcaggtcg agcacgccct tgcgccggtc cacccggccg tggaagagca
     3061 gcaccggcgg ctcgcgcagc gcgcccagcg ggcgctcggc cggcgtgaac cgccgggtgt
     3121 cggtggcgcc ggggacgatc gtgaaccgcg ccgggtcgct gccgaggttg ccgaccacct
     3181 cgtcgcggaa gctggcgctg ccgatcagca ccgcgctcga ggagtccacc accgtgcgca
     3241 tcgcctcggc gtgggtggtg cagcaggtgc ccaaccagtg gccgtcgccg ccctggatgc
     3301 tcaccacggc cggcagcccg gtctcccggg cggcggccag caccgccagg cccggcgggt
     3361 agccgtactg ggcgtgcagg acgtcgaagg gccgctcggc gtgcagcccg acgacggtgc
     3421 gcacgatctc gtcgatgtcg ccctcccagt cggcggggac gacggtctcg ccgcggctgg
     3481 gcagcgcgac gacctcgacg ccggccggga cgcggtcggg cgggggcggg ccgccgccgt
     3541 agacgcgggt gccggcctcg tcgtcgcggt actggctgac gagcgtgacc tcggagccga
     3601 gggcgaccag ctcgcgcagc aggttctccg cgtagacgct catgccgctg accgccggcc
     3661 agtagcggcg gctgacgaag caggtcctca tgcccgttcg gcctctctca gcgtcgcgat
     3721 cgcgcgcggc accatctcgt gcgcgcggtg cccgtcgcgg gagagctcga gggtgaccag
     3781 ccgctcgtag cccacgtccc gcagcgcccg cagcacggcg ggcaggtcga cgtccccctc
     3841 gtcgaggggc aggtggtcgt gcacgccgcg gcgcatgccc tcgacggcga ccgtgcccag
     3901 gtgcgcggcg aacgcggcga ccgcctcctg cggctcgtac gccccggcga cgacgcagtg
     3961 gccggtgtcg agcgccagcg tgatgcccgg cgcctcctcg gccagccggg cccagccgtc
     4021 gcagtcctcg accagcatcc cgggctcggg ctcgacggcc agggcgtagg aacgcccgcc
     4081 gtggctgtcg accagcgcgc gcacgccgtc gaccacccag ccccacgcct cgtcgcggtc
     4141 cacccccggc cgcggcacgc cggcccagaa gctgaccgcc tcggcgccca gcacctcggc
     4201 caggtcgcag gccagccgca ggtaggccag ccgccgcgcc cggcccgcgg cgtccggggt
     4261 gaccagcgtc ggctcgtgct ttccccgcgg gtcgagcagg tagcgggcgc cggtctcgac
     4321 gacgacaccc agccccagct cgtcgcagcg cgcccgcgtc ttctcggcct gcgcgagggc
     4381 gtcgggcgcg aacgggtcga ggtggacgac gtccagcgtg agcgcgaccc ccgcgtagcc
     4441 ggtgtcggcg aggagggaca gcgcgtcgga cagccggtgc gaggtcagcc cgttggtgtt
     4501 gtaggcgtac ctcagctccc tcggtgacct cgcgagctcg gtcactgcgc cagcacctcc
     4561 gcgaccgtgt gccggccggg ctcgcggtag agggcgtaga gcccgcccac ccgccggtcg
     4621 gcgcccgcgc ggtcgaacca ggccggcccc ccgagccgat cctcggcctc cgcggccagg
     4681 tgcacccccg cccagccgcc ggggtcggcg ccgacggcca ccagcgggtc gccgcgttcg
     4741 agcagccggc gcacaccgcg ctcgccgatc cgcccgtagg acatcgtctc gacctccagg
     4801 cccggcacca gcaccttggc cgcgaccgcg tcgccgacgg agggctgcag ctccaccagg
     4861 acgtcgtgcc ccgcggcgtg cagggcgtcg acgacggttc cgtgcaggtc gtcgccggac
     4921 caggtcggca ggtcggtcag cgcgacggtc ccccggcggg acagcacgct gccctgcagc
     4981 aggccgacca gcgcgccggt gcccatccgg gtccaggcca gcatcgcctc cagcgcgcgg
     5041 tcctcctcga ccagccgctc cggcgggtgc ccgccgcgcc aggagtcgag gtagcccggc
     5101 ggggtcgccg gcaggacgac gtcgaacgga ccgtgcatga acgccttgcg gctgcgcgcc
     5161 gaggcgaact cgtgcagcgc cttgcggacg gcggtgtcgc ggtcggggtg cgccgcctcg
     5221 ccgcacgccg tcgccatgac cggcaccggc tcggacaggt cgcgcgagca gccgaccgcg
     5281 tacacgtcgg ccacgccgaa ctccgtcgcc gccagcttca ccaccacgtc gatgcccgcg
     5341 gcgtcgagcc ggtcgagcag cgccagcgcg tcggggtcgc ggagcccggc gaggtccacc
     5401 acgacgccgc ggtccatcgc gcggaaggag gtggcgttcc cgtcgcgctg cagcacctcg
     5461 agcagcgcgt gcgcgaccgc ccggtcggcg tcgaacgccg cgccctgccc gttggtgatc
     5521 accgtggtca gccagccacc ggggggcggg gcgccgggca ggtcgtcggg cgcggaggcg
     5581 accagctccg cgggcaccag cacggtctcg ccgtcccgct gccgggtcat cggcagccac
     5641 tgcagcggcc ggtcgtcgtc gtaggcgctg ccggcctcca ggcagagggt gcgcgggtcg
     5701 gccacccggt cgcggccgtg cctccgggtc atctccgcgt aggagccctg ctcccgctcg
     5761 acgccccggt gcgcgcgcag cgacagtgcc atctcggcca tctcgcccag cgccccggtg
     5821 cgcgcctcct cgcgggtggc gccgtagccc agaccgctgc cgccggggtg ccgcgggccg
     5881 ggcggcagga ccgcgctgtg cagcggcacg tcgaggacgt cgaggccctc gatggcgaac
     5941 tcctcgacgg ttcccgggaa cgagtcgagg taccgctggg cggcggtcag ggtggacgtc
     6001 acagttcctc cagcgcgacg ggggcagcgt ccggcggccc ggacagcagc cgctgcacca
     6061 ggtggacgac gtggtcggtg gtcaccccgc ggaccagctc gaacggcgtc gcgacggcct
     6121 cgaagtccag tgcgccgacc acggtcaggt actcgcgcag ctcgccgtgc gacagcggga
     6181 tctgcgcgtg gaaggccttg tgcgcgctca gcgcgaccgg ggcgccggcc tcgtcgaggt
     6241 cgaccttgag cgagtcgccg cagaagagca cgccgcggcg gcggtcgtgc agcaccgagt
     6301 gcccggggaa gtggccgccg gtgcggtgca gggtgaggtc gggggccagc tccagctcgt
     6361 cgtccgccgg ccacgtgacc cggaaggcct tggtccactc caggtcccgg acgccgacgc
     6421 acaccacccg cggctcgagc tcctgctgca gctgccacag cgcgccgtag ccgtgcacgt
     6481 ggctggaggc cagcacgtcg aacccaccct tggcctcggc catccgccgc agctgggcga
     6541 gcacgtcggc ggtgtaccag ggggcgcact cgaagccgac caggccggcg tcgctctcga
     6601 tcacccagcc gcggctgtcc aggccgaagc gcgggtgcgt cccgaactcg gtgacgccct
     6661 cgacggcggt cggtcggcag aagccctgga ccagctcctc gacctgcgcg ggcgtcacga
     6721 actcgaagcc gttctcgggc agcgcgttgc ggacgtcggc gcagaccggg cagaccagcg
     6781 gcccgggctc tggccagcgc tgccagtgcc cgcagttggt gcaggcgtag gcgggcaggt
     6841 cgggcagcag cccgcggtag gggttggtca tctcgcgtct cccagggcgg tgaggaggag
     6901 gcggtgcagc gccaggtcgc gggcggcgtc gtacggccag ggcacccgcc cggcgaccgc
     6961 ggcggtgaag gcggcgaact gcgcggcgaa gggggagtcg tcggcgaagg ggacgtcgac
     7021 cgggtcgggc cggtgcagcc tgagcgaccc gcccgcggtc tggcccatcg tgtcgacggc
     7081 gacggccatc ccgcgtgtgc cgacgacctc gagccggcgg cgggggagcg cgtcgggggt
     7141 gttgaaggcg acgtgcaggt cgaccagcac gccggtggcg gtgcgcccgg acagcagcgc
     7201 gccgtcgtcc accgggtagt cctgcacccg ccgctgcagc agcgcgcgca gttccacgac
     7261 gtcctccccg agcagcacgc cggccaggtc gaggccgtgc ggggccaggt cgatggccgc
     7321 gccgccgccg gcccgcgccc ggtcgacccg ccagttgtcg tgcggccggc cgtcgggcgt
     7381 ccagtcggcg ggcagccagc agcagtagac gatccgcacc gcggtcaccg tgcccagctc
     7441 cggcagcagc tcgcgcagcc gcacgtgggc ggggtgccag cgctggtcgt acgccgtccc
     7501 gaggaggacg ccggcgtcgc gggcggcggt caccatcgcc cgcgcgtcgg cgacgtcggc
     7561 ggccagcggc ttctcgcaca gcaccgcctt gccggccgcg gccaccgcct cgaccacctc
     7621 gcggtgcgcg gcgttgggga cggcgacgta gaccgcgtcc aggcccggtg tggcgaggaa
     7681 ggcgccgagg tcggcgtgcg ccggggcgtc gacgggcatt cgggccagcg caccgggatc
     7741 gcggtcgtgc agcgcgacga tccgggcgcc cggtgtcgcg gcgagggcgg gcagcgcgtg
     7801 gtcacgggcc acccagccgc agccggcgac gccccacccg acgccgttca ccgcacacct
     7861 cctcggcgcc agatctgcac agtggcgccc atcagggcct cgatgggcgc cactgtgcag
     7921 atctcgcgtc ctcaccacgc ctccgggagg tcgacgagca gccggcggcg ggcggcgtcg
     7981 gcgggcagcg ggtcgggcca gcgggccggc aggtacgccg agcgcgggcc gtactcaccg
     8041 gcgtagcgct cgctcggcca gcgcagctcc ccgtcggcgt acagcgggtt ggggcgcagc
     8101 ggcggcagcg gctcgcccag gtcggccggg gcgggggaca gcgggtcgcc ggccaccagc
     8161 gccaccgcct cgctcctgtg cagcgcggcg gccggggcgg ggcgcggcgg ccggccctcg
     8221 agcagcgcgc cggtcagatc ggcgtcgtcg tagagcaggt cggtgccgag caccgctgcg
     8281 tagccctccg gcgtcagcgg ctccccgtgc gggtcggcga cgtgcgcgtg cccgacgacg
     8341 acggtgccac cgtccccggc gagctcgtgc atcgccgcgg cggcggccgg cttgtcgcgc
     8401 aggaagtaga aggcgtcgtg gcacagcacg taggccggcg caggcacgcc caggtcgggc
     8461 acgccggtca cgtcggcgca gacgtagcgc gccgacgggc agacgaagcg ccgcgccagc
     8521 cacagcttgg cccagacgac gtcgacgccc agcaggtcgg tgcagccgcg tcgggccagc
     8581 tcgcgcaggt gggtgcccgt gccgcaggcg acgtccacca ccggcctgct gcccggccag
     8641 tgctgctgca gcagcgccag cccggccagg tgggtggggt ccgaccagcg gtgggcgaag
     8701 tagtcggcga cccggcccat gccgagcagg tccatcgcct cgcgcagggt gcgcgccgcc
     8761 gggacgcggg ccagctgctc gggcggcggg gccggctcgg tccaccagtc gtcggcgtcg
     8821 gccagcagcg ccacgcgggc gcggtcgacc tcgccgcgcg ccagcaggcc ggccacctcc
     8881 gcgcgcagct cgtcgcgtcc ggcccgggcg tacgggatgc cgtcgaccac cgggaccgcc
     8941 ggagccgctg tgctcacagc ccggccgccg ccaggacgtc gaggtggaag gcctgcaccg
     9001 gccccgcgtg cacgagctcg aggtcgtcga gcgcctgcga cgcggtgaac gccgccgcgc
     9061 gcgcgtggtg gtgcacctgc agcacccggt cgaggacgtc ggcggcgtgg aaggcctgcg
     9121 actccggcgc gccggcgtcc gcccgcagcc tcagcaccgt gcgcagccgc tcggccagcg
     9181 ggccgggcag ggcggccagc tcgcgctcct ccagcgtcgt cacgacccgg tcgagcgccg
     9241 agccgagcag cacctcgccg gcgaacccgg cgtcgggcag caccacgttg tgcaggtggt
     9301 gggccagccc gacgaggaac ggcgccaccg ggtcggcacc gaacaccggg gcgacgagca
     9361 cgccgtagac ggcgacggtc aggcagtggt cgccgtggct ctccggcggc tcgacgacca
     9421 cccgcggcct ccccggggcg gtggccccgg cgcgcggctg gcggttgagc cgctcggcca
     9481 gcggaggcgg ctgcggcgtc gggacggcga gcggcagggc ctcgcgcagc cgggcccgca
     9541 ggccggcgtc cagcgggccg gcgacctcgt cgaagccgcg gcgcagcacg tcgcgcgcgt
     9601 cgtcgccggt caggcccgcc gtccggagca ccgcaccgtc gatgccggcc agccgggcgc
     9661 gggcgacggc cgccgccgtc tccgacagcg cgaccgcggc cgcgtcctca cccgcgacca
     9721 gccgccccca ggcgcgggcg aaggcccgct cggccagcga cccgggagcg tcggcgacac
     9781 ggacccgctt ggcgtcgccg acctcggtca gcagcgggcg gagctcggcg agggcggggg
     9841 agccgcccgt caccggccgg ccggcgcgcc ggcgacccag tcgagcagca cacgttcctg
     9901 ccggtgcagg gcgtgctcgg gggtgctgcc gtccggggac atcggcgcct tgaagaacca
     9961 gccgaactgg gtctgcacgc cgccctcccc gcgctgctgg gccaggtcgg tcagccgggc
    10021 cagctcgatg gccagcggcg cggccaggat cgagtcgcgg cactggaagt cgaccttgac
    10081 ctgcatgcgc tggccgagga agccgaccag gtcgatggcg tcccaggcct ccttctggtc
    10141 gccgcgcggg cggtagtagt cgatccgcac gacgtggtcc tcgaccgggt agccgaggat
    10201 cgagtcgagc acgctgccct tggtgttcag cttgctggcc agcgagtccg ggtcgtcgag
    10261 ggcctggccg tcgcggttgc cgaggatgtt ggtggagtac cagccctcga cggtgagcga
    10321 gcggctgcgg aaggccgggg cgagcaccgt cttgagcatc gtctggccgg tcttgccgtc
    10381 cttgccggcg accgggacgc cgcggctccc ggccagggcc accagcgcgg ggacgtcggc
    10441 ggccagcgac ggcgtgaagt tgacgtagcc gacgccctcg gcgatcgcgg cgtaggcgta
    10501 gaccatcgcc ggggtgatgg cccggtcgtc ggcgtccagc ccggcctcga acgcctcgac
    10561 cgtctgcagc gcgggcgcct ccgggtccgg ccagcgctcg gtggaggcca ggttcaccag
    10621 cacgagcccg tcgaggtcgt gctcctcgcg gaaccggcgc aggtcggccc ggacggcgtc
    10681 gacctgggcg cggcgggtct cggccagcac cacgttgccg ccagtgacgt tgcggcagaa
    10741 gtcggcgtcg ccggcagcgg gccagggcgt caccgaggac aggtgcggcc cggcctgctc
    10801 cagctggtgg gggtcgagga cgccgtgcag ctcggcggcc ttgcgcagat ccgtgccgtc
    10861 gaggtcccag cccccgacga cgaggtcggc gtacccggcc atcccggtca cctcctcgag
    10921 ggggcggccc tcgacctcca gccccgccag tggcagcccg gtcgtgtcac ccgtgccgtt
    10981 gcggagcagt tccagccccg cc
//
